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Gregory Mullen

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Alexander S G O'Neill; Timo K van den Berg; Gregory E D Mullen
Sialoadhesin - a macrophage-restricted marker of immunoregulation and inflammation.
Richard Tavaré; Jennifer Williams; Philip J Blower; Kevin Howland; Gregory E D Mullen
[Re(CO)(3)](+) labelling of a novel cysteine/hexahistidine tag: insights into binding mode by liquid chromatography-mass spectrometry.
Feng Qian; Kelly Rausch; Karine Reiter; Richard L Shimp; Yanling Zhang; Daming Zhu; Joan A Aebig; Lynn Lambert; Carole A Long; Laura B Martin; Louis H Miller; Gregory E D Mullen; Vu Nguyen; David Narum
Immunogenicity of self-associated aggregates and chemically cross-linked conjugates of the 42 kDa Plasmodium falciparum merozoite surface protein-1.

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All Publications

2013: Alexander S G O'Neill; Timo K van den Berg; Gregory E D Mullen
Sialoadhesin - a macrophage-restricted marker of immunoregulation and inflammation.
Immunology 2013;138(3):198-207.
2012: Richard Tavaré; Jennifer Williams; Philip J Blower; Kevin Howland; Gregory E D Mullen
[Re(CO)(3)](+) labelling of a novel cysteine/hexahistidine tag: insights into binding mode by liquid chromatography-mass spectrometry.
Journal of inorganic biochemistry 2012;114():24-7.
2012: Feng Qian; Kelly Rausch; Karine Reiter; Richard L Shimp; Yanling Zhang; Daming Zhu; Joan A Aebig; Lynn Lambert; Carole A Long; Laura B Martin; Louis H Miller; Gregory E D Mullen; Vu Nguyen; David Narum
Immunogenicity of self-associated aggregates and chemically cross-linked conjugates of the 42 kDa Plasmodium falciparum merozoite surface protein-1.
PloS one 2012;7(6):e36996.
2011: David J Berry; James R Ballinger; Robert C Hider; Alexander Koers; Yongmin Ma; Gregory E D Mullen; Saima Nawaz; Kavitha Sunassee; Richard Tavaré; Tao Zhou; Philip J Blower
Efficient bifunctional gallium-68 chelators for positron emission tomography: tris(hydroxypyridinone) ligands.
Chemical communications (Cambridge, England) 2011;47(25):7068-70.
2011: Maite Jauregui-Osoro; Peter A Williamson; Arnaud Glaria; Kavitha Sunassee; Putthiporn Charoenphun; Mark A Green; Gregory E D Mullen; Philip J Blower
Biocompatible inorganic nanoparticles for [18F]-fluoride binding with applications in PET imaging.
Dalton transactions (Cambridge, England : 2003) 2011;40(23):6226-37.
2011: Richard Tavaré; Pervinder Sagoo; Gopal Varama; Yakup Tanriver; Alice Warely; Sandra S Diebold; Richard Southworth; Tobias Schaeffter; Robert I Lechler; Reza Razavi; Giovanna Lombardi; Gregory E D Mullen
Monitoring of in vivo function of superparamagnetic iron oxide labelled murine dendritic cells during anti-tumour vaccination.
PloS one 2011;6(5):e19662.
2011: Adam Badar; Sarah DeFreitas; James M McDonnell; Norhakim Yahya; David Thakor; Reza Razavi; Richard Smith; Steven Sacks; Gregory E D Mullen
Recombinant complement receptor 2 radiolabeled with [99mTc(CO)3]+: a potential new radiopharmaceutical for imaging activated complement.
PloS one 2011;6(4):e18275.
2010: Mark A Pierce; Ruth D Ellis; Laura B Martin; Elissa Malkin; Eveline Tierney; Kazutoyo Miura; Michael P Fay; Joanne Marjason; Suzanne L Elliott; Gregory E D Mullen; Kelly Rausch; Daming Zhu; Carole A Long; Louis H Miller
Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults.
Vaccine 2010;28(10):2236-42.
2010: Ruth D Ellis; Laura B Martin; Donna Shaffer; Carole A Long; Kazutoyo Miura; Michael P Fay; David Narum; Daming Zhu; Gregory E D Mullen; Siddhartha Mahanty; Louis H Miller; Anna P Durbin
Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42)-C1/Alhydrogel with and without CPG 7909 in malaria naïve adults.
PloS one 2010;5(1):e8787.
2009: Issaka Sagara; Ruth D Ellis; Alassane Dicko; Mohamed B Niambele; Beh Kamate; Ousmane Guindo; Mady Sissoko; Michael P Fay; Merepen A Guindo; Ousmane Kante; SAYE Renion; Kazutoyo Miura; Carole A Long; Gregory E D Mullen; Mark Pierce; Laura B Martin; Kelly Rausch; Amagana Dolo; Dapa A Diallo; Louis H Miller; Ogobara K Doumbo
A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults.
Vaccine 2009;27(52):7292-8.
2009: Richard Tavaré; Rafael Torres Martin De Rosales; Philip J Blower; Gregory E D Mullen
Efficient site-specific radiolabeling of a modified C2A domain of synaptotagmin I with [99mTc(CO)3]+: a new radiopharmaceutical for imaging cell death.
Bioconjugate chemistry 2009;20(11):2071-81.
2009: Maria Cecilia Huaman; Gregory E D Mullen; Carole A Long; Siddhartha Mahanty
Plasmodium falciparum apical membrane antigen 1 vaccine elicits multifunctional CD4 cytokine-producing and memory T cells.
Vaccine 2009;27(38):5239-46.
2009: Kazutoyo Miura; Hong Zhou; Ababacar Diouf; Samuel E Moretz; Michael P Fay; Louis H Miller; Laura B Martin; Mark A Pierce; Ruth D Ellis; Gregory E D Mullen; Carole A Long
Anti-apical-membrane-antigen-1 antibody is more effective than anti-42-kilodalton-merozoite-surface-protein-1 antibody in inhibiting plasmodium falciparum growth, as determined by the in vitro growth inhibition assay.
Clinical and vaccine immunology : CVI 2009;16(7):963-8.
2009: Ruth D Ellis; Gregory E D Mullen; Mark Pierce; Laura B Martin; Kazutoyo Miura; Michael P Fay; Carole A Long; Donna Shaffer; Allan Saul; Louis H Miller; Anna P Durbin
A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel with CPG 7909, using two different formulations and dosing intervals.
Vaccine 2009;27(31):4104-9.
2009: Issaka Sagara; Alassane Dicko; Ruth D Ellis; Michael P Fay; Sory I Diawara; Mahamadoun H Assadou; Mady Sissoko; Mamady Kone; Abdoulbaki I Diallo; SAYE Renion; Merepen A Guindo; Ousmane Kante; Mohamed B Niambele; Kazutoyo Miura; Gregory E D Mullen; Mark Pierce; Laura B Martin; Amagana Dolo; Dapa A Diallo; Ogobara K Doumbo; Louis H Miller; Allan Saul
A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali.
Vaccine 2009;27(23):3090-8.
2009: Peter D Crompton; Marko Mircetic; Greta Weiss; Amy Baughman; Chiung-Yu Huang; David J Topham; John Treanor; Iñaki Sanz; F Eun-Hyung Lee; Anna P Durbin; Kazutoyo Miura; David Narum; Ruth D Ellis; Elissa Malkin; Gregory E D Mullen; Louis H Miller; Laura B Martin; Susan K Pierce
The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparum-specific memory B cells in malaria-naive individuals.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):3318-26.
2009: Feng Qian; Joan A Aebig; Karine Reiter; Emma Barnafo; Yanling Zhang; Richard L Shimp; Kelly M Rausch; David S Jones; Daming Zhu; Lynn Lambert; Gregory E D Mullen; David Narum; Louis H Miller; Yimin Wu
Enhanced antibody responses to Plasmodium falciparum Pfs28 induced in mice by conjugation to ExoProtein A of Pseudomonas aeruginosa with an improved procedure.
Microbes and infection / Institut Pasteur 2009;11(3):408-12.
2008: Kazutoyo Miura; Hong Zhou; Samuel E Moretz; Ababacar Diouf; Mahamadou A Thera; Amagana Dolo; Ogobara K Doumbo; Elissa Malkin; David Diemert; Louis H Miller; Gregory E D Mullen; Carole A Long
Comparison of biological activity of human anti-apical membrane antigen-1 antibodies induced by natural infection and vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(12):8776-83.
2008: Feng Qian; Kelly Rausch; Olga Muratova; Hong Zhou; Guanhong Song; Ababacar Diouf; Lynn Lambert; David Narum; Yimin Wu; Allan Saul; Louis H Miller; Carole A Long; Gregory E D Mullen
Addition of CpG ODN to recombinant Pseudomonas aeruginosa ExoProtein A conjugates of AMA1 and Pfs25 greatly increases the number of responders.
Vaccine 2008;26(20):2521-7.
2008: Gregory E D Mullen; Ruth D Ellis; Kazutoyo Miura; Elissa Malkin; Caroline Nolan; Mhorag Hay; Michael P Fay; Allan Saul; Daming Zhu; Kelly Rausch; Samuel Moretz; Hong Zhou; Carole A Long; Louis H Miller; John Treanor
Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria.
PloS one 2008;3(8):e2940.
2008: Alassane Dicko; Issaka Sagara; Ruth D Ellis; Kazutoyo Miura; Ousmane Guindo; Beh Kamate; Moussa Sogoba; Mohamed Balla Niambelé; Mady Sissoko; Mounirou Baby; Amagana Dolo; Gregory E D Mullen; Michael P Fay; Mark Pierce; Dapa A Diallo; Allan Saul; Louis H Miller; Ogobara K Doumbo
Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.
PloS one 2008;3(2):e1563.
2007: Gregory E D Mullen; Joan A Aebig; Gelu Dobrescu; Kelly Rausch; Lynn Lambert; Carole A Long; Aaron P Miles; Allan Saul
Enhanced antibody production in mice to the malaria antigen AMA1 by CPG 7909 requires physical association of CpG and antigen.
Vaccine 2007;25(29):5343-7.
2007: Joan A Aebig; Gregory E D Mullen; Gelu Dobrescu; Kelly Rausch; Lynn Lambert; Olubunmi Ajose-Popoola; Carole A Long; Allan Saul; Aaron P Miles
Formulation of vaccines containing CpG oligonucleotides and alum.
Journal of immunological methods 2007;323(2):139-46.
2007: Feng Qian; Yimin Wu; Olga Muratova; Hong Zhou; Gelu Dobrescu; Peter Duggan; Lambert Lynn; Guanhong Song; Yanling Zhang; Karine Reiter; Nicholas MacDonald; David Narum; Carole A Long; Louis H Miller; Allan Saul; Gregory E D Mullen
Conjugating recombinant proteins to Pseudomonas aeruginosa ExoProtein A: a strategy for enhancing immunogenicity of malaria vaccine candidates.
Vaccine 2007;25(20):3923-33.
2007: Alassane Dicko; David J Diemert; Issaka Sagara; Moussa Sogoba; Mohamed B Niambele; Mahamadoun H Assadou; Ousmane Guindo; Beh Kamate; Mounirou Baby; Mady Sissoko; Elissa Malkin; Michael P Fay; Mahamadou A Thera; Kazutoyo Miura; Amagana Dolo; Dapa A Diallo; Gregory E D Mullen; Carole A Long; Allan Saul; Ogobara K Doumbo; Louis H Miller
Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians.
PloS one 2007;2(10):e1045.
2006: Elke Bergmann-Leitner; Elizabeth H Duncan; Gregory E D Mullen; J Robert Burge; Farhat Khan; Carole A Long; Evelina Angov; Jeffrey A Lyon
Critical evaluation of different methods for measuring the functional activity of antibodies against malaria blood stage antigens.
The American journal of tropical medicine and hygiene 2006;75(3):437-42.
2006: Gregory E D Mullen; Birgitte K Giersing; Olubunmi Ajose-Popoola; Heather L Davis; Cheryl Kothe; Hong Zhou; Joan A Aebig; Gelu Dobrescu; Allan Saul; Carole A Long
Enhancement of functional antibody responses to AMA1-C1/Alhydrogel, a Plasmodium falciparum malaria vaccine, with CpG oligodeoxynucleotide.
Vaccine 2006;24(14):2497-505.
2005: Elissa Malkin; David J Diemert; Julie H McArthur; John R Perreault; Aaron P Miles; Birgitte K Giersing; Gregory E D Mullen; Andrew C Orcutt; Olga Muratova; May Awkal; Hong Zhou; Jin Wang; Anthony W Stowers; Carole A Long; Siddhartha Mahanty; Louis H Miller; Allan Saul; Anna P Durbin
Phase 1 clinical trial of apical membrane antigen 1: an asexual blood-stage vaccine for Plasmodium falciparum malaria.
Infection and immunity 2005;73(6):3677-85.
2004: Margaret N Kennedy; Gregory E D Mullen; Cynthia A Leifer; ChangWoo Lee; Alessandra Mazzoni; Kottarappat N Dileepan; David M Segal
A complex of soluble MD-2 and lipopolysaccharide serves as an activating ligand for Toll-like receptor 4.
The Journal of biological chemistry 2004;279(33):34698-704.
2003: Jessica K Bell; Gregory E D Mullen; Cynthia A Leifer; Alessandra Mazzoni; David Davies; David M Segal
Leucine-rich repeats and pathogen recognition in Toll-like receptors.
Trends in immunology 2003;24(10):528-33.
2003: Gregory E D Mullen; Margaret N Kennedy; Alberto Visintin; Alessandra Mazzoni; Cynthia A Leifer; David Davies; David M Segal
The role of disulfide bonds in the assembly and function of MD-2.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3919-24.
2003: Alessandra Mazzoni; Cynthia A Leifer; Gregory E D Mullen; Margaret N Kennedy; Dennis M Klinman; David M Segal
Cutting edge: histamine inhibits IFN-alpha release from plasmacytoid dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2269-73.
2002: Richard I Maurer; Philip J Blower; Jonathan R Dilworth; Christopher A Reynolds; Yifan Zheng; Gregory E D Mullen
Studies on the mechanism of hypoxic selectivity in copper bis(thiosemicarbazone) radiopharmaceuticals.
Journal of medicinal chemistry 2002;45(7):1420-31.
2002: Jason L J Dearling; Jason S Lewis; Gregory E D Mullen; Michael J Welch; Philip J Blower
Copper bis(thiosemicarbazone) complexes as hypoxia imaging agents: structure-activity relationships.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2002;7(3):249-59.
2000: Gregory E D Mullen; Philip J Blower; D J Price; Annie Powell; Mark J Howard; Michael J Went
Trithiacyclononane as a ligand for potential technetium and rhenium radiopharmaceuticals: synthesis of [M(9S3)(SC2H4SC2H4S)][BF4] (M = 99Tc, Re, 188Re) via C-S bond cleavage.
Inorganic chemistry 2000;39(18):4093-8.
1998: Jason L J Dearling; Jason S Lewis; Gregory E D Mullen; M T Rae; J Zweit; Philip J Blower
Design of hypoxia-targeting radiopharmaceuticals: selective uptake of copper-64 complexes in hypoxic cells in vitro.
European journal of nuclear medicine 1998;25(7):788-92.