FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

George Muller

Research Profile

Chemicals & Drugs

Living Beings

Mouse

Anatomy

Physiology

Concepts & Ideas

Co-author Network

Publications

TOP 3
Alexander L Ruchelman; Peter H Schafer; Michael A Shirley; Yang Tang; Weihong Zhang; Anastasia Parton; Darius Babusis; Lori Capone; Roger Chen; Laura G Corral; Jian Kang; Hon-Wah Man; Mehran F Moghaddam; George W Muller
Isosteric analogs of lenalidomide and pomalidomide: synthesis and biological activity.
Alexander L Ruchelman; Ling Zhang; Rama Krishna Narla; Heather K Raymon; Dorota Cedzik; Roger Chen; Alice Collette; Jim Leisten; Wei Liu; Ling Lu; Hon-Wah Man; George W Muller
1,1-Diarylalkenes as anticancer agents: dual inhibitors of tubulin polymerization and phosphodiesterase 4.
Huan N Vu; Walter J Miller; Sarah A O'Connor; Mei He; Peter H Schafer; Faribourz Payvandi; George W Muller; David I Stirling; Steven Libutti
CC-5079: a small molecule with MKP1, antiangiogenic, and antitumor activity.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of George Muller (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Alexander L Ruchelman; Peter H Schafer; Michael A Shirley; Yang Tang; Weihong Zhang; Anastasia Parton; Darius Babusis; Lori Capone; Roger Chen; Laura G Corral; Jian Kang; Hon-Wah Man; Mehran F Moghaddam; George W Muller
Isosteric analogs of lenalidomide and pomalidomide: synthesis and biological activity.
Bioorganic & medicinal chemistry letters 2013;23(1):360-5.
2011: Alexander L Ruchelman; Ling Zhang; Rama Krishna Narla; Heather K Raymon; Dorota Cedzik; Roger Chen; Alice Collette; Jim Leisten; Wei Liu; Ling Lu; Hon-Wah Man; George W Muller
1,1-Diarylalkenes as anticancer agents: dual inhibitors of tubulin polymerization and phosphodiesterase 4.
Bioorganic & medicinal chemistry 2011;19(21):6356-74.
2010: Huan N Vu; Walter J Miller; Sarah A O'Connor; Mei He; Peter H Schafer; Faribourz Payvandi; George W Muller; David I Stirling; Steven Libutti
CC-5079: a small molecule with MKP1, antiangiogenic, and antitumor activity.
The Journal of surgical research 2010;164(1):116-25.
2009: Ling Lu; Faribourz Payvandi; Lei Wu; Ling-Hua Zhang; Robert J Hariri; Hon-Wah Man; Roger S Chen; George W Muller; Christopher C W Hughes; David I Stirling; Peter H Schafer; J Blake Bartlett
The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions.
Microvascular research 2009;77(2):78-86.
2009: Petros X E Mouratidis; Kay W Colston; Jake Blake Bartlett; George W Muller; Hon-Wah Man; David Stirling; Angus G Dalgleish
Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells.
Pancreas 2009;38(1):78-84.
2007: Dominique Verhelle; Laura G Corral; Kevin Wong; Jessica H Mueller; Laure Moutouh-de Parseval; Kristen Jensen-Pergakes; Peter H Schafer; Roger Chen; Emilia Glezer; Gregory D Ferguson; Antonia Lopez-Girona; George W Muller; Helen A Brady; Kyle W H Chan
Lenalidomide and CC-4047 inhibit the proliferation of malignant B cells while expanding normal CD34+ progenitor cells.
Cancer research 2007;67(2):746-55.
2007: David P Mangiameli; Joseph A Blansfield; Stephan Kachala; Dominique Lorang; Peter H Schafer; George W Muller; David I Stirling; Steven Libutti
Combination therapy targeting the tumor microenvironment is effective in a model of human ocular melanoma.
Journal of translational medicine 2007;5():38.
2006: Mahmoud Kiaei; Susanne Petri; Khatuna Kipiani; Gabrielle Gardian; Dong-Kug Choi; Junyu Chen; Noel Y Calingasan; Peter H Schafer; George W Muller; Charles Stewart; Kenneth Hensley; M Flint Beal
Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(9):2467-73.
2006: Ling-Hua Zhang; Lei Wu; Heather K Raymon; Roger S Chen; Laura G Corral; Michael A Shirley; Rama Krishna Narla; Jim Gamez; George W Muller; David I Stirling; J Blake Bartlett; Peter H Schafer; Faribourz Payvandi
The synthetic compound CC-5079 is a potent inhibitor of tubulin polymerization and tumor necrosis factor-alpha production with antitumor activity.
Cancer research 2006;66(2):951-9.
2005: Faribourz Payvandi; Lei Wu; Syedah D Naziruddin; Maura Haley; Anastasia Parton; Peter H Schafer; Roger S Chen; George W Muller; Christopher C W Hughes; David I Stirling
Immunomodulatory drugs (IMiDs) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kappaB, OCT-1, or NF-AT.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2005;25(10):604-16.
2004: Faribourz Payvandi; Lei Wu; Maura Haley; Peter H Schafer; Ling-Hua Zhang; Roger S Chen; George W Muller; David I Stirling
Immunomodulatory drugs inhibit expression of cyclooxygenase-2 from TNF-alpha, IL-1beta, and LPS-stimulated human PBMC in a partially IL-10-dependent manner.
Cellular immunology 2004;230(2):81-8.
2004: J Blake Bartlett; A Michael; Ian A Clarke; Keith Dredge; Steve Nicholson; H Kristeleit; A Polychronis; Hardev Pandha; George W Muller; David I Stirling; Jerome B Zeldis; Angus G Dalgleish
Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers.
British journal of cancer 2004;90(5):955-61.
2003: Michael S Gee; Sosina Makonnen; Khalid A Al-Kofahi; Badrinath Roysam; Faribourz Payvandi; Hon-Wah Man; George W Muller; William M F Lee
Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition.
Cancer research 2003;63(23):8073-8.
2003: Hon-Wah Man; Laura G Corral; David I Stirling; George W Muller
Alpha-fluoro-substituted thalidomide analogues.
Bioorganic & medicinal chemistry letters 2003;13(20):3415-7.
2003: Peter H Schafer; Anita K Gandhi; Michelle A Loveland; Roger S Chen; Hon-Wah Man; Paul P M Schnetkamp; Gregor Wolbring; Sowmya Govinda; Laura G Corral; Faribourz Payvandi; George W Muller; David I Stirling
Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs.
The Journal of pharmacology and experimental therapeutics 2003;305(3):1222-32.
2003: Steve K Teo; Yong Chen; George W Muller; Roger S Chen; Steve D Thomas; David I Stirling; Reddy S Chandula
Chiral inversion of the second generation IMiD CC-4047 (ACTIMID ) in human plasma and phosphate-buffered saline.
Chirality 2003;15(4):348-51.
2003: J Blake Marriott; Ian A Clarke; Anna Czajka; Keith Dredge; Kay Childs; Hon-Wah Man; Peter H Schafer; Sowmya Govinda; George W Muller; David I Stirling; Angus G Dalgleish
A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins.
Cancer research 2003;63(3):593-9.
2003: Francisco Chung; Brian Palmer; George W Muller; Hon-Wah Man; Philip Kestell; Bruce C Baguley; Lai-Ming Ching
Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
Oncology research 2003;14(2):75-82.
2002: Keith Dredge; J Blake Marriott; C D Macdonald; Hon-Wah Man; R Chen; George W Muller; David Stirling; Angus G Dalgleish
Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects.
British journal of cancer 2002;87(10):1166-72.
2002: Keith Dredge; J Blake Marriott; Stephen Todryk; George W Muller; Roger Chen; David I Stirling; Angus G Dalgleish
Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Th1-type immunity.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):4914-9.
2001: John L Prehn; Carol J Landers; George W Muller; Hon-Wah Man; David I Stirling; Stephan R Targan
Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues.
Journal of clinical immunology 2001;21(5):357-64.
2001: Faith E Davies; Noopur Raje; Teru Hideshima; Suzanne Lentzsch; Gloria Young; Yu-Tzu Tai; Boris Lin; klaus podar; Deepak Gupta; Dharminder Chauhan; Steve P Treon; Paul G Richardson; Robert Schlossman; G J Morgan; George W Muller; David I Stirling; Kenneth C Anderson
Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma.
Blood 2001;98(1):210-6.
1999: Laura G Corral; Patrick A J Haslett; George W Muller; Roger Chen; LM Wong; C J Ocampo; RT Patterson; David I Stirling; Gilla Kaplan
Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):380-6.
1999: George W Muller; Roger Chen; S Y Huang; Laura G Corral; LM Wong; RT Patterson; Y Chen; Gilla Kaplan; David I Stirling
Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production.
Bioorganic & medicinal chemistry letters 1999;9(11):1625-30.
1998: George W Muller; M G Shire; LM Wong; Laura G Corral; RT Patterson; Y Chen; David I Stirling
Thalidomide analogs and PDE4 inhibition.
Bioorganic & medicinal chemistry letters 1998;8(19):2669-74.
1997: Andre L Moreira; Laura G Corral; W Ye; B Johnson; David Stirling; George W Muller; Victoria Freedman; Gilla Kaplan
Thalidomide and thalidomide analogs reduce HIV type 1 replication in human macrophages in vitro.
AIDS research and human retroviruses 1997;13(10):857-63.
1996: George W Muller; Laura G Corral; M G Shire; H Wang; A Moreira; Gilla Kaplan; D I Stirling
Structural modifications of thalidomide produce analogs with enhanced tumor necrosis factor inhibitory activity.
Journal of medicinal chemistry 1996;39(17):3238-40.
1996: Laura G Corral; George W Muller; Andre L Moreira; Y Chen; M Wu; D Stirling; Gilla Kaplan
Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity.
Molecular medicine (Cambridge, Mass.) 1996;2(4):506-15.