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Ralph Müller

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TOP 3
D Ruffoni; Leah Rae Donahue; T Kohler; Ralph Müller; Romain Voide; A J Wirth; Harry van Lenthe
High-throughput quantification of the mechanical competence of murine femora - A highly automated approach for large-scale genetic studies.
Luc Nimeskern; Paul Gatenholm; Héctor Martínez Ávila; Ralph Müller; Johan Sundberg; Kathryn S Stok
Mechanical evaluation of bacterial nanocellulose as an implant material for ear cartilage replacement.
Duncan J Webster; Philipp Schneider; Sarah L Dallas; Ralph Müller
Studying osteocytes within their environment.

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All Publications

2013: D Ruffoni; Leah Rae Donahue; T Kohler; Ralph Müller; Romain Voide; A J Wirth; Harry van Lenthe
High-throughput quantification of the mechanical competence of murine femora - A highly automated approach for large-scale genetic studies.
Bone 2013;55(1):216-21.
2013: Luc Nimeskern; Paul Gatenholm; Héctor Martínez Ávila; Ralph Müller; Johan Sundberg; Kathryn S Stok
Mechanical evaluation of bacterial nanocellulose as an implant material for ear cartilage replacement.
Journal of the mechanical behavior of biomedical materials 2013;22():12-21.
2013: Duncan J Webster; Philipp Schneider; Sarah L Dallas; Ralph Müller
Studying osteocytes within their environment.
Bone 2013;54(2):285-95.
2013: Adi Cohen; Serge Cremers; David W Dempster; Joan M Lappe; Donald J McMahon; Ralph Müller; Thomas L Nickolas; Robert R Recker; Emily M Stein; Julie Stubby; Polly Young; Hua Zhou; Alexander Zwahlen; Elizabeth Shane
Teriparatide for idiopathic osteoporosis in premenopausal women: a pilot study.
The Journal of clinical endocrinology and metabolism 2013;98(5):1971-81.
2013: Thomas L Mueller; Ralph Müller; Samuel E Basler; Harry van Lenthe
Time-lapsed imaging of implant fixation failure in human femoral heads.
Medical engineering & physics 2013;35(5):636-43.
2013: Roberto Carretta; Benoit Luisier; Ralph Müller; Edgar Stüssi; Daniel Bernoulli; silvio lorenzetti
Novel method to analyze post-yield mechanical properties at trabecular bone tissue level.
Journal of the mechanical behavior of biomedical materials 2013;20():6-18.
2013: Philipp Schneider; Marco Stampanoni; Romain Voide; Leah Rae Donahue; Ralph Müller
The importance of the intracortical canal network for murine bone mechanics.
Bone 2013;53(1):120-8.
2013: Elad Wasserman; Duncan Webster; Malka Attar-Namdar; Gisela Kuhn; Ralph Müller; Itai Bab
Differential load-regulated global gene expression in mouse trabecular osteocytes.
Bone 2013;53(1):14-23.
2013: S Rigozzi; Ralph Müller; A Stemmer; Jess Snedeker
Tendon glycosaminoglycan proteoglycan sidechains promote collagen fibril sliding-AFM observations at the nanoscale.
Journal of biomechanics 2013;46(4):813-8.
2013: Roberto Carretta; silvio lorenzetti; Ralph Müller
Towards patient-specific material modeling of trabecular bone post-yield behavior.
International journal for numerical methods in biomedical engineering 2013;29(2):250-72.
2013: F M Lambers; K Koch; G Kuhn; J Ripoll; M Rudin; F A Schulte; F Stuker; C Weigt; Ralph Müller
Longitudinal in vivo imaging of bone formation and resorption using fluorescence molecular tomography.
Bone 2013;52(2):587-95.
2013: A Butscher; N Doebelin; L Galea; O Loeffel; Marc Bohner; Ralph Müller
Moisture based three-dimensional printing of calcium phosphate structures for scaffold engineering.
Acta biomaterialia 2013;9(2):5369-78.
2013: Friederike A Schulte; Duncan J Webster; Davide Ruffoni; David Christen; Gisela Kuhn; Floor M Lambers; Ralph Müller
Local mechanical stimuli regulate bone formation and resorption in mice at the tissue level.
PloS one 2013;8(4):e62172.
2013: Farhad Rikhtegar; Kathryn S Stok; Christophe Wyss; Ralph Müller; Fernando Pacheco; Dimos Poulikakos; Ryan J Choo; Aldo Ferrari; Heng Ge; Vartan Kurtcuoglu
Compound ex vivo and in silico method for hemodynamic analysis of stented arteries.
PloS one 2013;8(3):e58147.
2013: Friederike A Schulte; Duncan J Webster; Alexander Zwahlen; Davide Ruffoni; Duncan Betts; Gisela Kuhn; Floor M Lambers; Ralph Müller
Strain-adaptive in silico modeling of bone adaptation--a computer simulation validated by in vivo micro-computed tomography data.
Bone 2013;52(1):485-92.
2012: Gadi Pelled; Samuela Rigozzi; Jess G Snedeker; Yoram Zilberman; Ayelet Ben-Arav; Zulma Gazit; Nadav Kimelman-Bleich; Ralph Müller; Dan Gazit
Smad8/BMP2-engineered mesenchymal stem cells induce accelerated recovery of the biomechanical properties of the Achilles tendon.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2012;30(12):1932-9.
2012: Andreas Trüssel; Ralph Müller; Duncan Webster
Toward mechanical systems biology in bone.
Annals of biomedical engineering 2012;40(11):2475-87.
2012: Elena Schuh; Kathryn S Stok; Sandra Hofmann; Ralph Müller; Holger Notbohm; Nicole Rotter
The influence of matrix elasticity on chondrocyte behavior in 3D.
Journal of tissue engineering and regenerative medicine 2012;6(10):e31-42.
2012: Adi Cohen; David W Dempster; Thomas Kohler; Joan M Lappe; Donald J McMahon; Ralph Müller; Thomas L Nickolas; Robert R Recker; Emily M Stein; Polly Young; Hua Zhou; Alexander Zwahlen; Elizabeth Shane
Increased marrow adiposity in premenopausal women with idiopathic osteoporosis.
The Journal of clinical endocrinology and metabolism 2012;97(8):2782-91.
2012: Andreas J Wirth; Ralph Müller; G Harry van Lenthe
The discrete nature of trabecular bone microarchitecture affects implant stability.
Journal of biomechanics 2012;45(6):1060-7.
2012: David Christen; Alina Levchuk; Philipp Schneider; Stefan Schori; Steven K Boyd; Ralph Müller
Deformable image registration and 3D strain mapping for the quantitative assessment of cortical bone microdamage.
Journal of the mechanical behavior of biomedical materials 2012;8():184-93.
2012: Davide Ruffoni; Juri A Steiner; Ralph Müller; Ian H Parkinson; Andreas J Wirth; Harry van Lenthe
The different contributions of cortical and trabecular bone to implant anchorage in a human vertebra.
Bone 2012;50(3):733-8.
2012: Benjamin BW Thimm; Philipp Schneider; Roberto Carretta; Sandra Hofmann; Ralph Müller
Imaging of cellular spread on a three-dimensional scaffold by means of a novel cell-labeling technique for high-resolution computed tomography.
Tissue engineering. Part C, Methods 2012;18(3):167-75.
2012: D Ruffoni; Ralph Müller; Harry van Lenthe
Mechanisms of reduced implant stability in osteoporotic bone.
Biomechanics and modeling in mechanobiology 2012;11(3-4):313-23.
2012: Floor M Lambers; Kathleen Koch; Gisela Kuhn; Friederike A Schulte; Ralph Müller
Longitudinal assessment of in vivo bone dynamics in a mouse tail model of postmenopausal osteoporosis.
Calcified tissue international 2012;90(2):108-19.
2012: Elena Schuh; Kathryn Stok; Sandra Hofmann; Ralph Müller; Holger Notbohm; Nicole Rotter
Chondrocyte redifferentiation in 3D: the effect of adhesion site density and substrate elasticity.
Journal of biomedical materials research. Part A 2012;100(1):38-47.
2012: Andre Butscher; Nicola Doebelin; Annika Ernstberger; Roman Heuberger; Christian Roth; Philipp Rudolf von Rohr; Marc Bohner; Ralph Müller
Printability of calcium phosphate powders for three-dimensional printing of tissue engineering scaffolds.
Acta biomaterialia 2012;8(1):373-85.
2011: Romain Voide; Philipp Schneider; Marco Stampanoni; Martin Stauber; Harry van Lenthe; Ralph Müller
The importance of murine cortical bone microstructure for microcrack initiation and propagation.
Bone 2011;49(6):1186-93.
2011: Adi Cohen; Serge Cremers; David W Dempster; Thomas Kohler; Joan M Lappe; Jeanette LeMaster; Donald J McMahon; Ralph Müller; Thomas L Nickolas; Robert R Recker; Halley Rogers; Clifford J Rosen; Ronald B Staron; Emily M Stein; Harry van Lenthe; Andreas J Wirth; Hua Zhou; Alexander Zwahlen; Elizabeth Shane
Abnormal bone microarchitecture and evidence of osteoblast dysfunction in premenopausal women with idiopathic osteoporosis.
The Journal of clinical endocrinology and metabolism 2011;96(10):3095-105.
2011: silvio lorenzetti; Ralph Müller; Roberto Carretta; Edgar Stüssi
A new device and method for measuring the elastic modulus of single trabeculae.
Medical engineering & physics 2011;33(8):993-1000.
2011: Andreas J Wirth; Peter Arbenz; Cyril Flaig; Jörg Goldhahn; Ralph Müller; Harry van Lenthe
Implant stability is affected by local bone microstructural quality.
Bone 2011;49(3):473-8.
2011: Philipp Schneider; Roger Wepf; Matias Meier; Ralph Müller
Serial FIB/SEM imaging for quantitative 3D assessment of the osteocyte lacuno-canalicular network.
Bone 2011;49(2):304-11.
2011: Thomas L Mueller; David Christen; Steve Sandercott; Steven K Boyd; Bert Van Rietbergen; Felix Eckstein; Eva-Maria Lochmüller; Ralph Müller; Harry van Lenthe
Computational finite element bone mechanics accurately predicts mechanical competence in the human radius of an elderly population.
Bone 2011;48(6):1232-8.
2011: Benjamin BW Thimm; Silke Wüst; Sandra Hofmann; Henri Hagenmüller; Ralph Müller
Initial cell pre-cultivation can maximize ECM mineralization by human mesenchymal stem cells on silk fibroin scaffolds.
Acta biomaterialia 2011;7(5):2218-28.
2011: Thomas L Mueller; Andreas J Wirth; Harry van Lenthe; Joerg Goldhahn; Jason Schense; Virginia Jamieson; Peter Messmer; Daniel Uebelhart; Dominik Weishaupt; Marcus Egermann; Ralph Müller
Mechanical stability in a human radius fracture treated with a novel tissue-engineered bone substitute: a non-invasive, longitudinal assessment using high-resolution pQCT in combination with finite element analysis.
Journal of tissue engineering and regenerative medicine 2011;5(5):415-20.
2011: A Butscher; Marc Bohner; S Hofmann; Ludwig J Gauckler; Ralph Müller
Structural and material approaches to bone tissue engineering in powder-based three-dimensional printing.
Acta biomaterialia 2011;7(3):907-20.
2011: Duncan Webster; Ralph Müller
In silico models of bone remodeling from macro to nano--from organ to cell.
Wiley interdisciplinary reviews. Systems biology and medicine 2011;3(2):241-51.
2011: Nora Hild; Oliver D Schneider; Dirk Mohn; Norman A Luechinger; Fabian M Koehler; Sandra Hofmann; Jolanda R Vetsch; Benjamin BW Thimm; Ralph Müller; Wendelin J Stark
Two-layer membranes of calcium phosphate/collagen/PLGA nanofibres: in vitro biomineralisation and osteogenic differentiation of human mesenchymal stem cells.
Nanoscale 2011;3(2):401-9.
2010: Duncan Webster; Elad Wasserman; Martin Ehrbar; Franz Weber; Itai Bab; Ralph Müller
Mechanical loading of mouse caudal vertebrae increases trabecular and cortical bone mass-dependence on dose and genotype.
Biomechanics and modeling in mechanobiology 2010;9(6):737-47.
2010: Philipp Schneider; Matias Meier; Roger Wepf; Ralph Müller
Towards quantitative 3D imaging of the osteocyte lacuno-canalicular network.
Bone 2010;47(5):848-58.
2010: Ilan Kallai; Harry van Lenthe; Davide Ruffoni; Yoram Zilberman; Ralph Müller; Gadi Pelled; Dan Gazit
Quantitative, structural, and image-based mechanical analysis of nonunion fracture repaired by genetically engineered mesenchymal stem cells.
Journal of biomechanics 2010;43(12):2315-20.
2010: Thomas P Kraehenbuehl; Martin Stauber; Martin Ehrbar; Franz Weber; Heike Hall; Ralph Müller
Effects of μCT radiation on tissue engineered bone-like constructs.
Biomedizinische Technik. Biomedical engineering 2010;55(4):245-50.
2010: Mary L Bouxsein; Stephen K Boyd; Blaine A Christiansen; Robert E Guldberg; Karl Jepsen; Ralph Müller
Guidelines for assessment of bone microstructure in rodents using micro-computed tomography.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(7):1468-86.
2010: Kathryn S Stok; Danièle Noël; Florence Apparailly; David Gould; Yuti Chernajovsky; Christian Jorgensen; Ralph Müller
Quantitative imaging of cartilage and bone for functional assessment of gene therapy approaches in experimental arthritis.
Journal of tissue engineering and regenerative medicine 2010;4(5):387-94.
2010: David Christen; Duncan James Webster; Ralph Müller
Multiscale modelling and nonlinear finite element analysis as clinical tools for the assessment of fracture risk.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2010;368(1920):2653-68.
2010: S Rigozzi; Ralph Müller; Jess Snedeker
Collagen fibril morphology and mechanical properties of the Achilles tendon in two inbred mouse strains.
Journal of anatomy 2010;216(6):724-31.
2010: Kathryn S Stok; Gina Lisignoli; Sandra Cristino; Andrea Facchini; Ralph Müller
Mechano-functional assessment of human mesenchymal stem cells grown in three-dimensional hyaluronan-based scaffolds for cartilage tissue engineering.
Journal of biomedical materials research. Part A 2010;93(1):37-45.
2010: Esther Cory; Ara Nazarian; entezari vahid; Vartan Vartanians; Ralph Müller; Brian D Snyder
Compressive axial mechanical properties of rat bone as functions of bone volume fraction, apparent density and micro-ct based mineral density.
Journal of biomechanics 2010;43(5):953-60.
2010: Yankel Gabet; David Kohavi; Romain Voide; Thomas L Mueller; Ralph Müller; Itai Bab
Endosseous implant anchorage is critically dependent on mechanostructural determinants of peri-implant bone trabeculae.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(3):575-83.
2010: Adi Cohen; David W Dempster; Ralph Müller; X Edward Guo; Thomas L Nickolas; Xiaole (Shirley) Liu; X H Zhang; A J Wirth; Harry van Lenthe; T Kohler; Donald J McMahon; Hua Zhou; Mishaela R Rubin; John P Bilezikian; J M Lappe; R R Recker; Elizabeth Shane
Assessment of trabecular and cortical architecture and mechanical competence of bone by high-resolution peripheral computed tomography: comparison with transiliac bone biopsy.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2010;21(2):263-73.
2010: Henri Hagenmüller; Marco Hitz; Hans P Merkle; Lorenz Meinel; Ralph Müller
Design and validation of a novel bioreactor principle to combine online micro-computed tomography monitoring and mechanical loading in bone tissue engineering.
The Review of scientific instruments 2010;81(1):014303.
2009: Ara Nazarian; Dieter Meier; Ralph Müller; Brian D Snyder
Functional dependence of cancellous bone shear properties on trabecular microstructure evaluated using time-lapsed micro-computed tomographic imaging and torsion testing.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2009;27(12):1667-74.
2009: Thomas L Mueller; Harry van Lenthe; Martin Stauber; Christian Gratzke; Felix Eckstein; Ralph Müller
Regional, age and gender differences in architectural measures of bone quality and their correlation to bone mechanical competence in the human radius of an elderly population.
Bone 2009;45(5):882-91.
2009: Kathryn S Stok; Gadi Pelled; Yoram Zilberman; Ilan Kallai; Jörg Goldhahn; Dan Gazit; Ralph Müller
Revealing the interplay of bone and cartilage in osteoarthritis through multimodal imaging of murine joints.
Bone 2009;45(3):414-22.
2009: Philipp Schneider; Thomas Krucker; Eric Meyer; Alexandra Ulmann-Schuler; Bruno Weber; Marco Stampanoni; Ralph Müller
Simultaneous 3D visualization and quantification of murine bone and bone vasculature using micro-computed tomography and vascular replica.
Microscopy research and technique 2009;72(9):690-701.
2009: Kathryn S Stok; Ralph Müller
Morphometric characterization of murine articular cartilage--novel application of confocal laser scanning microscopy.
Microscopy research and technique 2009;72(9):650-8.
2009: Ara Nazarian; entezari vahid; Vartan Vartanians; Ralph Müller; Brian D Snyder
An improved method to assess torsional properties of rodent long bones.
Journal of biomechanics 2009;42(11):1720-5.
2009: Romain Voide; Philipp Schneider; Martin Stauber; P Wyss; Marco Stampanoni; U Sennhauser; Harry van Lenthe; Ralph Müller
Time-lapsed assessment of microcrack initiation and propagation in murine cortical bone at submicrometer resolution.
Bone 2009;45(2):164-73.
2009: S Rigozzi; Ralph Müller; Jess Snedeker
Local strain measurement reveals a varied regional dependence of tensile tendon mechanics on glycosaminoglycan content.
Journal of biomechanics 2009;42(10):1547-52.
2009: Ralph Müller
Hierarchical microimaging of bone structure and function.
Nature reviews. Rheumatology 2009;5(7):373-81.
2009: Friederike A Gerhard; Duncan J Webster; Harry van Lenthe; Ralph Müller
In silico biology of bone modelling and remodelling: adaptation.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2009;367(1895):2011-30.
2009: Philipp Schneider; Romain Voide; Marco Stampanoni; Ralph Müller
Post-processing technique for improved assessment of hard tissues in the submicrometer domain using local synchrotron radiation-based computed tomography.
Biomedizinische Technik. Biomedical engineering 2009;54(1):48-54.
2009: Thomas L Mueller; Martin Stauber; Thomas Kohler; Felix Eckstein; Ralph Müller; Harry van Lenthe
Non-invasive bone competence analysis by high-resolution pQCT: an in vitro reproducibility study on structural and mechanical properties at the human radius.
Bone 2009;44(2):364-71.
2009: Tommy Noh; Yankel Gabet; Jon Cogan; Yunfan Shi; Archana Tank; Tomoyo Sasaki; Braden Criswell; Alexis Dixon; Christopher Lee; Joseph Tam; Thomas Kohler; Eran Segev; Lisa Kockeritz; James Woodgett; Ralph Müller; Yang Chai; Elisheva Smith; Itai Bab; Baruch Frenkel
Lef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific manner.
PloS one 2009;4(5):e5438.
2009: Jess Snedeker; G Pelled; Yoram Zilberman; A Ben Arav; E Huber; Ralph Müller; Dan Gazit
An analytical model for elucidating tendon tissue structure and biomechanical function from in vivo cellular confocal microscopy images.
Cells, tissues, organs 2009;190(2):111-9.
2009: Ara Nazarian; E Cory; Ralph Müller; Brian D Snyder
Shortcomings of DXA to assess changes in bone tissue density and microstructure induced by metabolic bone diseases in rat models.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2009;20(1):123-32.
2008: Ara Nazarian; Michael Bauernschmitt; Christian Eberle; Dieter Meier; Ralph Müller; Brian D Snyder
Design and validation of a testing system to assess torsional cancellous bone failure in conjunction with time-lapsed micro-computed tomographic imaging.
Journal of biomechanics 2008;41(16):3496-501.
2008: Ara Nazarian; Dietrich von Stechow; David Zurakowski; Ralph Müller; Brian D Snyder
Bone volume fraction explains the variation in strength and stiffness of cancellous bone affected by metastatic cancer and osteoporosis.
Calcified tissue international 2008;83(6):368-79.
2008: Vanessa Fritz; Danièle Noël; Céline Bouquet; Paule Opolon; Romain Voide; Florence Apparailly; Pascale Louis-Plence; Carine Bouffi; Hicham Drissi; Chao Xie; Michel Perricaudet; Ralph Müller; Edward Schwarz; Christian Jorgensen
Antitumoral activity and osteogenic potential of mesenchymal stem cells expressing the urokinase-type plasminogen antagonist amino-terminal fragment in a murine model of osteolytic tumor.
Stem cells (Dayton, Ohio) 2008;26(11):2981-90.
2008: Harry van Lenthe; Romain Voide; Steven K Boyd; Ralph Müller
Tissue modulus calculated from beam theory is biased by bone size and geometry: implications for the use of three-point bending tests to determine bone tissue modulus.
Bone 2008;43(4):717-23.
2008: Harry van Lenthe; Thomas L Mueller; Andreas J Wirth; Ralph Müller
Quantification of bone structural parameters and mechanical competence at the distal radius.
Journal of orthopaedic trauma 2008;22(8 Suppl):S66-72.
2008: Ara Nazarian; Brian D Snyder; David Zurakowski; Ralph Müller
Quantitative micro-computed tomography: a non-invasive method to assess equivalent bone mineral density.
Bone 2008;43(2):302-11.
2008: Romain Voide; Harry van Lenthe; Ralph Müller
Bone morphometry strongly predicts cortical bone stiffness and strength, but not toughness, in inbred mouse models of high and low bone mass.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008;23(8):1194-203.
2008: Romain Voide; Harry van Lenthe; Ralph Müller
Differential effects of bone structural and material properties on bone competence in C57BL/6 and C3H/He inbred strains of mice.
Calcified tissue international 2008;83(1):61-9.
2008: Romain Voide; Harry van Lenthe; Ralph Müller
Femoral stiffness and strength critically depend on loading angle: a parametric study in a mouse-inbred strain.
Biomedizinische Technik. Biomedical engineering 2008;53(3):122-9.
2008: Stefan Heinzer; Gisela Kuhn; Thomas Krucker; Eric Meyer; Alexandra Ulmann-Schuler; Marco Stampanoni; Max Gassmann; Hugo H Marti; Ralph Müller; Johannes Vogel
Novel three-dimensional analysis tool for vascular trees indicates complete micro-networks, not single capillaries, as the angiogenic endpoint in mice overexpressing human VEGF(165) in the brain.
NeuroImage 2008;39(4):1549-58.
2008: Martin Stauber; Ralph Müller
Micro-computed tomography: a method for the non-destructive evaluation of the three-dimensional structure of biological specimens.
Methods in molecular biology (Clifton, N.J.) 2008;455():273-92.
2007: Susanne Schweizer; Bodo Hattendorf; Philipp Schneider; Beat Aeschlimann; Ludwig Gauckler; Ralph Müller; Detlef Günther
Preparation and characterization of calibration standards for bone density determination by micro-computed tomography.
The Analyst 2007;132(10):1040-5.
2007: Thomas Kohler; Martin Stauber; Leah Rae Donahue; Ralph Müller
Automated compartmental analysis for high-throughput skeletal phenotyping in femora of genetic mouse models.
Bone 2007;41(4):659-67.
2007: Philipp Schneider; Martin Stauber; Romain Voide; Marco Stampanoni; Leah Rae Donahue; Ralph Müller
Ultrastructural properties in cortical bone vary greatly in two inbred strains of mice as assessed by synchrotron light based micro- and nano-CT.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22(10):1557-70.
2007: Henri Hagenmüller; Sandra Hofmann; Thomas Kohler; Hans P Merkle; David L Kaplan; Gordana Vunjak-Novakovic; Ralph Müller; Lorenz Meinel
Non-invasive time-lapsed monitoring and quantification of engineered bone-like tissue.
Annals of biomedical engineering 2007;35(10):1657-67.
2007: Chi Hyun Kim; Henry Zhang; George Mikhail; Dietrich von Stechow; Ralph Müller; Han Sung Kim; X Edward Guo
Effects of thresholding techniques on microCT-based finite element models of trabecular bone.
Journal of biomechanical engineering 2007;129(4):481-6.
2007: Harry van Lenthe; Henri Hagenmüller; Marc Bohner; Scott J Hollister; Lorenz Meinel; Ralph Müller
Nondestructive micro-computed tomography for biological imaging and quantification of scaffold-bone interaction in vivo.
Biomaterials 2007;28(15):2479-90.
2007: Roberto J Fajardo; Ralph Müller; Rich A Ketcham; Matthew Colbert
Nonhuman anthropoid primate femoral neck trabecular architecture and its relationship to locomotor mode.
Anatomical record (Hoboken, N.J. : 2007) 2007;290(4):422-36.
2007: Vanessa Fritz; Pascale Louis-Plence; Florence Apparailly; Danièle Noël; Romain Voide; Arnaud Pillon; Jean-Claude Nicolas; Ralph Müller; Christian Jorgensen
Micro-CT combined with bioluminescence imaging: a dynamic approach to detect early tumor-bone interaction in a tumor osteolysis murine model.
Bone 2007;40(4):1032-40.
2007: Sandra Hofmann; Henri Hagenmüller; Annette M Koch; Ralph Müller; Gordana Vunjak-Novakovic; David L Kaplan; Hans P Merkle; Lorenz Meinel
Control of in vitro tissue-engineered bone-like structures using human mesenchymal stem cells and porous silk scaffolds.
Biomaterials 2007;28(6):1152-62.
2007: G Kuhn; M Schultz; Ralph Müller; Frank J Rühli
Diagnostic value of micro-CT in comparison with histology in the qualitative assessment of historical human postcranial bone pathologies.
Homo : internationale Zeitschrift für die vergleichende Forschung am Menschen 2007;58(2):97-115.
2007: Andreas A Kurth; Soo-Zin Kim; Marie Shea; Frieder Bauss; Wilson C Hayes; Ralph Müller
Preventative ibandronate treatment has the most beneficial effect on the microstructure of bone in experimental tumor osteolysis.
Journal of bone and mineral metabolism 2007;25(2):86-92.
2007: Ara Nazarian; John Muller; David Zurakowski; Ralph Müller; Brian D Snyder
Densitometric, morphometric and mechanical distributions in the human proximal femur.
Journal of biomechanics 2007;40(11):2573-9.
2006: Lorenz uebersax; Henri Hagenmüller; Sandra Hofmann; Emanuel Gruenblatt; Ralph Müller; Gordana Vunjak-Novakovic; David L Kaplan; Hans P Merkle; Lorenz Meinel
Effect of scaffold design on bone morphology in vitro.
Tissue engineering 2006;12(12):3417-29.
2006: Harry van Lenthe; Martin Stauber; Ralph Müller
Specimen-specific beam models for fast and accurate prediction of human trabecular bone mechanical properties.
Bone 2006;39(6):1182-9.
2006: Ara Nazarian; Martin Stauber; David Zurakowski; Brian D Snyder; Ralph Müller
The interaction of microstructure and volume fraction in predicting failure in cancellous bone.
Bone 2006;39(6):1196-202.
2006: Jess Snedeker; Gadi Pelled; Yoram Zilberman; Friederike Gerhard; Ralph Müller; Dan Gazit
Endoscopic cellular microscopy for in vivo biomechanical assessment of tendon function.
Journal of biomedical optics 2006;11(6):064010.
2006: Simone C Rizzi; Martin Ehrbar; Sven Halstenberg; George Raeber; Hugo G Schmoekel; Henri Hagenmüller; Ralph Müller; Franz Weber; Jeffrey A Hubbell
Recombinant protein-co-PEG networks as cell-adhesive and proteolytically degradable hydrogel matrixes. Part II: biofunctional characteristics.
Biomacromolecules 2006;7(11):3019-29.
2006: Marie-Cécile von Doernberg; Brigitte von Rechenberg; Marc Bohner; Sonja Grünenfelder; Harry van Lenthe; Ralph Müller; Beat Gasser; Robert Mathys; Gamal Baroud; Jörg Auer
In vivo behavior of calcium phosphate scaffolds with four different pore sizes.
Biomaterials 2006;27(30):5186-98.
2006: Stefan Heinzer; Thomas Krucker; Marco Stampanoni; Rafael Abela; Eric P Meyer; Alexandra Schuler; Philipp Schneider; Ralph Müller
Hierarchical microimaging for multiscale analysis of large vascular networks.
NeuroImage 2006;32(2):626-36.
2006: Philipp Thurner; P Wyss; Romain Voide; Martin Stauber; Marco Stampanoni; U Sennhauser; Ralph Müller
Time-lapsed investigation of three-dimensional failure and damage accumulation in trabecular bone using synchrotron light.
Bone 2006;39(2):289-99.
2006: Ralph Müller; Harry van Lenthe
Trabecular bone failure at the microstructural level.
Current osteoporosis reports 2006;4(2):80-6.
2006: Martin Stauber; Laurent Rapillard; Harry van Lenthe; Philippe K Zysset; Ralph Müller
Importance of individual rods and plates in the assessment of bone quality and their contribution to bone stiffness.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(4):586-95.
2006: Martin Stauber; Ralph Müller
Volumetric spatial decomposition of trabecular bone into rods and plates--a new method for local bone morphometry.
Bone 2006;38(4):475-84.
2006: Martin Stauber; Ralph Müller
Age-related changes in trabecular bone microstructures: global and local morphometry.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2006;17(4):616-26.
2006: Jess Snedeker; Felix Walz; M H Muser; G Schroeder; T L Mueller; Ralph Müller
Microstructural insight into pedestrian pelvic fracture as assessed by high-resolution computed tomography.
Journal of biomechanics 2006;39(14):2709-13.
2006: Steven K Boyd; Ralph Müller
Smooth surface meshing for automated finite element model generation from 3D image data.
Journal of biomechanics 2006;39(7):1287-95.
2005: T Kohler; M Beyeler; D Webster; Ralph Müller
Compartmental bone morphometry in the mouse femur: reproducibility and resolution dependence of microtomographic measurements.
Calcified tissue international 2005;77(5):281-90.
2005: Olivier Gauthier; Ralph Müller; Dietrich von Stechow; Bernard Lamy; Pierre WEISS; Jean-Michel Bouler; Eric Aguado; Guy Daculsi
In vivo bone regeneration with injectable calcium phosphate biomaterial: a three-dimensional micro-computed tomographic, biomechanical and SEM study.
Biomaterials 2005;26(27):5444-53.
2005: Ara Nazarian; Martin Stauber; Ralph Müller
Design and implementation of a novel mechanical testing system for cellular solids.
Journal of biomedical materials research. Part B, Applied biomaterials 2005;73(2):400-11.
2005: Philipp Thurner; Ralph Müller; G Raeber; U Sennhauser; Jeffrey A Hubbell
3D morphology of cell cultures: a quantitative approach using micrometer synchrotron light tomography.
Microscopy research and technique 2005;66(6):289-98.
2005: Ralph Müller
Long-term prediction of three-dimensional bone architecture in simulations of pre-, peri- and post-menopausal microstructural bone remodeling.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2005;16 Suppl 2():S25-35.
2005: Elisheva Smith; Todd E Meyerrose; Thomas Kohler; Malka Namdar-Attar; Natti Bab; Olga Lahat; Tommy Noh; Jingjing Li; Mazen W Karaman; Joseph G Hacia; Ting T Chen; Jan A Nolta; Ralph Müller; Itai Bab; Baruch Frenkel
Leaky ribosomal scanning in mammalian genomes: significance of histone H4 alternative translation in vivo.
Nucleic acids research 2005;33(4):1298-308.
2004: Ralph Müller; Mary Hannan; Susan Y Smith; Frieder Bauss
Intermittent ibandronate preserves bone quality and bone strength in the lumbar spine after 16 months of treatment in the ovariectomized cynomolgus monkey.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(11):1787-96.
2004: Alison B Pratt; Franz Weber; Hugo G Schmoekel; Ralph Müller; Jeffrey A Hubbell
Synthetic extracellular matrices for in situ tissue engineering.
Biotechnology and bioengineering 2004;86(1):27-36.
2004: Mary L Bouxsein; Toru Uchiyama; Clifford J Rosen; Kathryn L Shultz; Leah Rae Donahue; Charles H Turner; Saunak Sen; Gary Churchill; Ralph Müller; Wesley G Beamer
Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(4):587-99.
2004: Hugo G Schmoekel; Jason C Schense; Franz Weber; Klaus W Grätz; Dania Gnägi; Ralph Müller; Jeffrey A Hubbell
Bone healing in the rat and dog with nonglycosylated BMP-2 demonstrating low solubility in fibrin matrices.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2004;22(2):376-81.
2004: Martin Stauber; Martin Huber; Harry van Lenthe; Steven K Boyd; Ralph Müller
A finite element beam-model for efficient simulation of large-scale porous structures.
Computer methods in biomechanics and biomedical engineering 2004;7(1):9-16.
2004: Ara Nazarian; Ralph Müller
Time-lapsed microstructural imaging of bone failure behavior.
Journal of biomechanics 2004;37(1):55-65.
2003: Chi Hyun Kim; Erica Takai; Hua Zhou; Dietrich von Stechow; Ralph Müller; David W Dempster; X Edward Guo
Trabecular bone response to mechanical and parathyroid hormone stimulation: the role of mechanical microenvironment.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(12):2116-25.
2003: Matthias P Lutolf; Franz Weber; Hugo G Schmoekel; Jason C Schense; Thomas Kohler; Ralph Müller; Jeffrey A Hubbell
Repair of bone defects using synthetic mimetics of collagenous extracellular matrices.
Nature biotechnology 2003;21(5):513-8.
2003: Dietrich von Stechow; Susan Fish; Dror Yahalom; Itai Bab; Michael Chorev; Ralph Müller; Joseph M Alexander
Does simvastatin stimulate bone formation in vivo?
BMC musculoskeletal disorders 2003;4():8.
2003: Dietrich von Stechow; Khaled Balto; Philip Stashenko; Ralph Müller
Three-dimensional quantitation of periradicular bone destruction by micro-computed tomography.
Journal of endodontics 2003;29(4):252-6.
2002: Ralph Müller
The Zürich experience: one decade of three-dimensional high-resolution computed tomography.
Topics in magnetic resonance imaging : TMRI 2002;13(5):307-22.
2001: Allison R Pettit; H Ji; Dietrich von Stechow; Ralph Müller; Steven R Goldring; Y Choi; C Benoist; Ellen M Gravallese
TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis.
The American journal of pathology 2001;159(5):1689-99.
2001: Patrick H F Nicholson; Ralph Müller; XG Cheng; Peter Rüegsegger; Georges Van der Perre; Jan Dequeker; Steven Boonen
Quantitative ultrasound and trabecular architecture in the human calcaneus.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(10):1886-92.
2000: Andreas A Kurth; Soo-Zin Kim; Frieder Bauss; Ralph Müller; L Hovy
[Anti-osteolytic therapy preserves trabecular structure and mechanical properties of bone in tumor osteolysis].
Zeitschrift für Orthopädie und ihre Grenzgebiete 2000;138(2):146-51.
2000: E D Cindik; Marcus Maurer; M K Hannan; Ralph Müller; W C Hayes; L Hovy; A A Kurth
Phenotypical characterization of c-kit receptor deficient mouse femora using non-destructive high-resolution imaging techniques and biomechanical testing.
Technology and health care : official journal of the European Society for Engineering and Medicine 2000;8(5):267-75.
2000: Khaled Balto; Ralph Müller; D C Carrington; Justine Dobeck; Philip Stashenko
Quantification of periapical bone destruction in mice by micro-computed tomography.
Journal of dental research 2000;79(1):35-40.
1999: Tor Hildebrand; Andres Laib; Ralph Müller; Jan Dequeker; Peter Rüegsegger
Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(7):1167-74.
1999: Bert Van Rietbergen; Ralph Müller; D Ulrich; Peter Rüegsegger; Rik Huiskes
Tissue stresses and strain in trabeculae of a canine proximal femur can be quantified from computer reconstructions.
Journal of biomechanics 1999;32(4):443-51.
1999: Bert Van Rietbergen; Ralph Müller; D Ulrich; Peter Rüegsegger; Rik Huiskes
Tissue stresses and strain in trabeculae of a canine proximal femur can be quantified from computer reconstructions.
Journal of biomechanics 1999;32(2):165-73.
1998: Ralph Müller; S C Gerber; W C Hayes
Micro-compression: a novel technique for the nondestructive assessment of local bone failure.
Technology and health care : official journal of the European Society for Engineering and Medicine 1998;6(5-6):433-44.
1998: Patrick H F Nicholson; Ralph Müller; G Lowet; XG Cheng; Tor Hildebrand; Peter Rüegsegger; Georges Van der Perre; Jan Dequeker; Steven Boonen
Do quantitative ultrasound measurements reflect structure independently of density in human vertebral cancellous bone?
Bone 1998;23(5):425-31.
1998: Ralph Müller; H Van Campenhout; B Van Damme; Georges Van der Perre; Jan Dequeker; Tor Hildebrand; Peter Rüegsegger
Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography.
Bone 1998;23(1):59-66.
1997: XG Cheng; Patrick H F Nicholson; G Lowet; Steven Boonen; Y Sun; Peter Rüegsegger; Ralph Müller; Jan Dequeker
Prevalence of trabecular microcallus formation in the vertebral body and the femoral neck.
Calcified tissue international 1997;60(5):479-84.
1997: D Ulrich; Tor Hildebrand; Bert Van Rietbergen; Ralph Müller; Peter Rüegsegger
The quality of trabecular bone evaluated with micro-computed tomography, FEA and mechanical testing.
Studies in health technology and informatics 1997;40():97-112.
1997: Ralph Müller; Peter Rüegsegger
Micro-tomographic imaging for the nondestructive evaluation of trabecular bone architecture.
Studies in health technology and informatics 1997;40():61-79.
1996: Ralph Müller; Tor Hildebrand; Hans Jörg Häuselmann; Peter Rüegsegger
In vivo reproducibility of three-dimensional structural properties of noninvasive bone biopsies using 3D-pQCT.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(11):1745-50.
1996: Ralph Müller; Peter Rüegsegger
Analysis of mechanical properties of cancellous bone under conditions of simulated bone atrophy.
Journal of biomechanics 1996;29(8):1053-60.
1996: Ralph Müller; B Koller; Tor Hildebrand; Andres Laib; S Gianolini; Peter Rüegsegger
Resolution dependency of microstructural properties of cancellous bone based on three-dimensional mu-tomography.
Technology and health care : official journal of the European Society for Engineering and Medicine 1996;4(1):113-9.
1996: Ralph Müller; M Hahn; M Vogel; G Delling; Peter Rüegsegger
Morphometric analysis of noninvasively assessed bone biopsies: comparison of high-resolution computed tomography and histologic sections.
Bone 1996;18(3):215-20.
1996: Peter Rüegsegger; B Koller; Ralph Müller
A microtomographic system for the nondestructive evaluation of bone architecture.
Calcified tissue international 1996;58(1):24-9.
1995: Ralph Müller; Peter Rüegsegger
Three-dimensional finite element modelling of non-invasively assessed trabecular bone structures.
Medical engineering & physics 1995;17(2):126-33.
1994: Markus Scheidegger; Ralph Müller; Peter Boesiger
Magnetic resonance angiography: methods and its applications to the coronary arteries.
Technology and health care : official journal of the European Society for Engineering and Medicine 1994;2(4):255-65.
1994: Ralph Müller; Tor Hildebrand; Peter Rüegsegger
Non-invasive bone biopsy: a new method to analyse and display the three-dimensional structure of trabecular bone.
Physics in medicine and biology 1994;39(1):145-64.