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Rainer Müller

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Jaime Salazar; Rainer H Müller; Jan P Möschwitzer
Performance comparison of two novel combinative particle-size-reduction technologies.
Jan P Möschwitzer; Rainer H Müller
Factors influencing the release kinetics of drug nanocrystal-loaded pellet formulations.
M Jansch; ANIL B JINDAL; A Samad; B Majee Sharmila; P V Devarajan; Rainer H Müller
Influence of particle shape on plasma protein adsorption and macrophage uptake.

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All Publications

2013: Jaime Salazar; Rainer H Müller; Jan P Möschwitzer
Performance comparison of two novel combinative particle-size-reduction technologies.
Journal of pharmaceutical sciences 2013;102(5):1636-49.
2013: Jan P Möschwitzer; Rainer H Müller
Factors influencing the release kinetics of drug nanocrystal-loaded pellet formulations.
Drug development and industrial pharmacy 2013;39(5):762-9.
2013: M Jansch; ANIL B JINDAL; A Samad; B Majee Sharmila; P V Devarajan; Rainer H Müller
Influence of particle shape on plasma protein adsorption and macrophage uptake.
Die Pharmazie 2013;68(1):27-33.
2013: Heni Rachmawati; Loaye Al Shaal; Rainer H Müller; Cornelia M Keck
Development of curcumin nanocrystal: physical aspects.
Journal of pharmaceutical sciences 2013;102(1):204-14.
2012: M Jansch; Eckart Rühl; P Stumpf; C Graf; Rainer H Müller
Adsorption kinetics of plasma proteins on ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles.
International journal of pharmaceutics 2012;428(1-2):125-33.
2012: Jaime Salazar; Rainer H Müller; Antoine Ghanem; Jan P Möschwitzer
Nanocrystals: comparison of the size reduction effectiveness of a novel combinative method with conventional top-down approaches.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012;81(1):82-90.
2012: Kasongo Wa Kasongo; Rainer H Müller; Roderick B Walker
The use of hot and cold high pressure homogenization to enhance the loading capacity and encapsulation efficiency of nanostructured lipid carriers for the hydrophilic antiretroviral drug, didanosine for potential administration to paediatric patients.
Pharmaceutical development and technology 2012;17(3):353-62.
2012: S Doktorovova; C M Lopes; P Martins-Lopes; Rainer H Müller; R Shegokar; A M Silva; Eliana B. Souto
Modified Rose Bengal assay for surface hydrophobicity evaluation of cationic solid lipid nanoparticles (cSLN).
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;45(5):606-12.
2012: Rainer H Müller; D Harden; C M Keck
Development of industrially feasible concentrated 30% and 40% nanoemulsions for intravenous drug delivery.
Drug development and industrial pharmacy 2012;38(4):420-30.
2011: S Kobierski; Rainer H Müller; K Ofori-Kwakye; C M Keck
Resveratrol nanosuspensions: interaction of preservatives with nanocrystal production.
Die Pharmazie 2011;66(12):942-7.
2011: Kasongo Wa Kasongo; Rainer H Müller; Jana Pardeike; Roderick B Walker
Selection and characterization of suitable lipid excipients for use in the manufacture of didanosine-loaded solid lipid nanoparticles and nanostructured lipid carriers.
Journal of pharmaceutical sciences 2011;100(12):5185-96.
2011: Jaime Salazar; Rainer H Müller; Oliver Heinzerling; Jan P Möschwitzer
Process optimization of a novel production method for nanosuspensions using design of experiments (DoE).
International journal of pharmaceutics 2011;420(2):395-403.
2011: Khalil Mitri; Cecilia Anselmi; Sven Gohla; Ranjita Shegokar; Rainer H Müller
Lutein nanocrystals as antioxidant formulation for oral and dermal delivery.
International journal of pharmaceutics 2011;420(1):141-6.
2011: Loaye Al Shaal; Ranjita Shegokar; Rainer H Müller
Production and characterization of antioxidant apigenin nanocrystals as a novel UV skin protective formulation.
International journal of pharmaceutics 2011;420(1):133-40.
2011: R Shegokar; K K Singh; Rainer H Müller
Production & stability of stavudine solid lipid nanoparticles--from lab to industrial scale.
International journal of pharmaceutics 2011;416(2):461-70.
2011: Rainer H Müller; Ranjita Shegokar; Cornelia M Keck
20 years of lipid nanoparticles (SLN and NLC): present state of development and industrial applications.
Current drug discovery technologies 2011;8(3):207-27.
2011: Kasongo Wa Kasongo; Rainer H Müller; Mirko Jansch; Roderick B Walker
Evaluation of the in vitro differential protein adsorption patterns of didanosine-loaded nanostructured lipid carriers (NLCs) for potential targeting to the brain.
Journal of liposome research 2011;21(3):245-54.
2011: S Nikolić; Cecilia Anselmi; C M Keck; Rainer H Müller
Skin photoprotection improvement: synergistic interaction between lipid nanoparticles and organic UV filters.
International journal of pharmaceutics 2011;414(1-2):276-84.
2011: Khalil Mitri; Cecilia Anselmi; Sven Gohla; Ranjita Shegokar; Rainer H Müller
Lipid nanocarriers for dermal delivery of lutein: preparation, characterization, stability and performance.
International journal of pharmaceutics 2011;414(1-2):267-75.
2011: J Pardeike; C Schmidt; I Volz; Rainer H Müller
Nanostructured lipid carriers as delivery system for the phopholipase A2 inhibitors PX-18 and PX-13 for dermal application.
Die Pharmazie 2011;66(5):357-61.
2011: Rainer H Müller; SH Gohla; Cornelia M Keck
State of the art of nanocrystals--special features, production, nanotoxicology aspects and intracellular delivery.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2011;78(1):1-9.
2011: Kasongo Wa Kasongo; Ranjita Shegokar; Rainer H Müller; Roderick B Walker
Formulation development and in vitro evaluation of didanosine-loaded nanostructured lipid carriers for the potential treatment of AIDS dementia complex.
Drug development and industrial pharmacy 2011;37(4):396-407.
2011: M Muchow; Philippe Maincent; Rainer H Müller; C M Keck
Production and characterization of testosterone undecanoate-loaded NLC for oral bioavailability enhancement.
Drug development and industrial pharmacy 2011;37(1):8-14.
2010: L Al Shaal; Rainer H Müller; R Shegokar
smartCrystal combination technology--scale up from lab to pilot scale and long term stability.
Die Pharmazie 2010;65(12):877-84.
2010: Ranjita Shegokar; Rainer H Müller
Nanocrystals: industrially feasible multifunctional formulation technology for poorly soluble actives.
International journal of pharmaceutics 2010;399(1-2):129-39.
2010: Jana Pardeike; Kay Schwabe; Rainer H Müller
Influence of nanostructured lipid carriers (NLC) on the physical properties of the Cutanova Nanorepair Q10 cream and the in vivo skin hydration effect.
International journal of pharmaceutics 2010;396(1-2):166-73.
2010: Jana Pardeike; Rainer H Müller
Nanosuspensions: a promising formulation for the new phospholipase A2 inhibitor PX-18.
International journal of pharmaceutics 2010;391(1-2):322-9.
2010: Rainer H Müller; Cornelia M Keck
Pharmaceutical nanoparticles--from their innovative origin to their future.
International journal of pharmaceutics 2010;390(1):1-2.
2010: L Al Shaal; Rainer H Müller; C M Keck
Preserving hesperetin nanosuspensions for dermal application.
Die Pharmazie 2010;65(2):86-92.
2009: S Kobierski; K Ofori-Kwakye; Rainer H Müller; C M Keck
Resveratrol nanosuspensions for dermal application--production, characterization, and physical stability.
Die Pharmazie 2009;64(11):741-7.
2009: Jana Pardeike; Rainer H Müller
Dermal and ocular safety of the new phospholipase A2 inhibitors PX-18 and PX-13 formulated as drug nanosuspension.
Journal of biomedical nanotechnology 2009;5(4):437-44.
2009: M Muchow; E I Schmitz; N Despatova; P Maincent; Rainer H Müller
Omega-3 fatty acids-loaded lipid nanoparticles for patient-convenient oral bioavailability enhancement.
Die Pharmazie 2009;64(8):499-504.
2009: Varaporn Buraphacheep Junyaprasert; Veerawat Teeranachaideekul; Eliana B. Souto; Prapaporn Boonme; Rainer H Müller
Q10-loaded NLC versus nanoemulsions: stability, rheology and in vitro skin permeation.
International journal of pharmaceutics 2009;377(1-2):207-14.
2009: Hend M Shubar; Ildiko R Dunay; Sabrina Lachenmaier; Margitta Dathe; Faris Nadiem Bushrab; Rachmat Mauludin; Rainer H Müller; Rudolf Fitzner; Klaus Borner; Oliver Liesenfeld
The role of apolipoprotein E in uptake of atovaquone into the brain in murine acute and reactivated toxoplasmosis.
Journal of drug targeting 2009;17(4):257-67.
2009: Prabhat Mishra; Loaye Al Shaal; Rainer H Müller; Cornelia M Keck
Production and characterization of Hesperetin nanosuspensions for dermal delivery.
International journal of pharmaceutics 2009;371(1-2):182-9.
2009: Rachmat Mauludin; Rainer H Müller; Cornelia M Keck
Development of an oral rutin nanocrystal formulation.
International journal of pharmaceutics 2009;370(1-2):202-9.
2009: Rachmat Mauludin; Rainer H Müller; Cornelia M Keck
Kinetic solubility and dissolution velocity of rutin nanocrystals.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;36(4-5):502-10.
2009: Medha Joshi; Rainer H Müller
Lipid nanoparticles for parenteral delivery of actives.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2009;71(2):161-72.
2009: Jana Pardeike; Aiman Hommoss; Rainer H Müller
Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products.
International journal of pharmaceutics 2009;366(1-2):170-84.
2008: Veerawat Teeranachaideekul; Prapaporn Boonme; Eliana B. Souto; Rainer H Müller; Varaporn Buraphacheep Junyaprasert
Influence of oil content on physicochemical properties and skin distribution of Nile red-loaded NLC.
Journal of controlled release : official journal of the Controlled Release Society 2008;128(2):134-41.
2008: Cornelia M Keck; Rainer H Müller
Size analysis of submicron particles by laser diffractometry--90% of the published measurements are false.
International journal of pharmaceutics 2008;355(1-2):150-63.
2008: Veerawat Teeranachaideekul; Varaporn Buraphacheep Junyaprasert; Eliana B. Souto; Rainer H Müller
Development of ascorbyl palmitate nanocrystals applying the nanosuspension technology.
International journal of pharmaceutics 2008;354(1-2):227-34.
2008: Veerawat Teeranachaideekul; Eliana B. Souto; Rainer H Müller; Varaporn Buraphacheep Junyaprasert
Physicochemical characterization and in vitro release studies of ascorbyl palmitate-loaded semi-solid nanostructured lipid carriers (NLC gels).
Journal of microencapsulation 2008;25(2):111-20.
2008: Rainer H Müller; S A Runge; V Ravelli; A F Thünemann; Wolfgang Mehnert; Eliana B. Souto
Cyclosporine-loaded solid lipid nanoparticles (SLN): drug-lipid physicochemical interactions and characterization of drug incorporation.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;68(3):535-44.
2008: Jens-Uwe A H Junghanns; Rainer H Müller
Nanocrystal technology, drug delivery and clinical applications.
International journal of nanomedicine 2008;3(3):295-309.
2007: Veerawat Teeranachaideekul; Rainer H Müller; Varaporn Buraphacheep Junyaprasert
Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC)--effects of formulation parameters on physicochemical stability.
International journal of pharmaceutics 2007;340(1-2):198-206.
2007: Veerawat Teeranachaideekul; Eliana B. Souto; Varaporn Buraphacheep Junyaprasert; Rainer H Müller
Cetyl palmitate-based NLC for topical delivery of Coenzyme Q(10) - development, physicochemical characterization and in vitro release studies.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;67(1):141-8.
2007: Rainer H Müller; R D Petersen; A Hommoss; J Pardeike
Nanostructured lipid carriers (NLC) in cosmetic dermal products.
Advanced drug delivery reviews 2007;59(6):522-30.
2007: Eliana B. Souto; Rainer H Müller
Rheological and in vitro release behaviour of clotrimazole-containing aqueous SLN dispersions and commercial creams.
Die Pharmazie 2007;62(7):505-9.
2006: Jan Möschwitzer; Rainer H Müller
New method for the effective production of ultrafine drug nanocrystals.
Journal of nanoscience and nanotechnology 2006;6(9-10):3145-53.
2006: Rainer H Müller; S Runge; V Ravelli; Wolfgang Mehnert; A F Thünemann; Eliana B. Souto
Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLN) versus drug nanocrystals.
International journal of pharmaceutics 2006;317(1):82-9.
2006: Eliana B. Souto; Wolfgang Mehnert; Rainer H Müller
Polymorphic behaviour of Compritol888 ATO as bulk lipid and as SLN and NLC.
Journal of microencapsulation 2006;23(4):417-33.
2006: Eliana B. Souto; Rainer H Müller
Investigation of the factors influencing the incorporation of clotrimazole in SLN and NLC prepared by hot high-pressure homogenization.
Journal of microencapsulation 2006;23(4):377-88.
2006: H Weyhers; S Ehlers; Helmut Hahn; Eliana B. Souto; Rainer H Müller
Solid lipid nanoparticles (SLN)--effects of lipid composition on in vitro degradation and in vivo toxicity.
Die Pharmazie 2006;61(6):539-44.
2006: Eliana B. Souto; Rainer H Müller
The use of SLN and NLC as topical particulate carriers for imidazole antifungal agents.
Die Pharmazie 2006;61(5):431-7.
2006: Andrea Gessner; Bernd-R Paulke; Rainer H Müller; Torsten M Göppert
Protein rejecting properties of PEG-grafted nanoparticles: influence of PEG-chain length and surface density evaluated by two-dimensional electrophoresis and bicinchoninic acid (BCA)-proteinassay.
Die Pharmazie 2006;61(4):293-7.
2006: Jan Möschwitzer; Rainer H Müller
Spray coated pellets as carrier system for mucoadhesive drug nanocrystals.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2006;62(3):282-7.
2005: Torsten M Göppert; Rainer H Müller
Adsorption kinetics of plasma proteins on solid lipid nanoparticles for drug targeting.
International journal of pharmaceutics 2005;302(1-2):172-86.
2005: Eliana B. Souto; Rainer H Müller; SH Gohla
A novel approach based on lipid nanoparticles (SLN) for topical delivery of alpha-lipoic acid.
Journal of microencapsulation 2005;22(6):581-92.
2005: Norma Hernández-Trejo; Oliver Kayser; Hartwig Steckel; Rainer H Müller
Characterization of nebulized buparvaquone nanosuspensions--effect of nebulization technology.
Journal of drug targeting 2005;13(8-9):499-507.
2005: Eliana B. Souto; SH Gohla; Rainer H Müller
Rheology of nanostructured lipid carriers (NLC) suspended in a viscoelastic medium.
Die Pharmazie 2005;60(9):671-3.
2005: Eliana B. Souto; Rainer H Müller
SLN and NLC for topical delivery of ketoconazole.
Journal of microencapsulation 2005;22(5):501-10.
2005: Torsten M Göppert; Rainer H Müller
Protein adsorption patterns on poloxamer- and poloxamine-stabilized solid lipid nanoparticles (SLN).
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2005;60(3):361-72.
2005: Franziska Rank; Hans-Jörg Scheuermann; Thomas Wozniewski; Rainer H Müller
Managing compliance in production-insights and comparisons in chemical-pharmaceutical companies.
PDA journal of pharmaceutical science and technology / PDA 2005;59(4):233-9.
2005: E Zimmermann; Eliana B. Souto; Rainer H Müller
Physicochemical investigations on the structure of drug-free and drug-loaded solid lipid nanoparticles (SLN) by means of DSC and 1H NMR.
Die Pharmazie 2005;60(7):508-13.
2005: Eliana B. Souto; Cecilia Anselmi; Marisanna Centini; Rainer H Müller
Preparation and characterization of n-dodecyl-ferulate-loaded solid lipid nanoparticles (SLN).
International journal of pharmaceutics 2005;295(1-2):261-8.
2005: Torsten M Göppert; Rainer H Müller
Polysorbate-stabilized solid lipid nanoparticles as colloidal carriers for intravenous targeting of drugs to the brain: comparison of plasma protein adsorption patterns.
Journal of drug targeting 2005;13(3):179-87.
2005: Anne Saupe; Sylvia A Wissing; Andreas Lenk; Corinna Schmidt; Rainer H Müller
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) -- structural investigations on two different carrier systems.
Bio-medical materials and engineering 2005;15(5):393-402.
2004: Ildiko R Dunay; Markus M Heimesaat; Faris Nadiem Bushrab; Rainer H Müller; Hartmut Stocker; Keikawus Arastéh; Michael Kurowski; Rudolf Fitzner; Klaus Borner; Oliver Liesenfeld
Atovaquone maintenance therapy prevents reactivation of toxoplasmic encephalitis in a murine model of reactivated toxoplasmosis.
Antimicrobial agents and chemotherapy 2004;48(12):4848-54.
2004: Jan Möschwitzer; Georg Achleitner; Herbert Pomper; Rainer H Müller
Development of an intravenously injectable chemically stable aqueous omeprazole formulation using nanosuspension technology.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(3):615-9.
2004: A Lippacher; Rainer H Müller; Karsten Mäder
Liquid and semisolid SLN dispersions for topical application: rheological characterization.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(3):561-7.
2004: Eliana B. Souto; Sylvia A Wissing; CM Barbosa; Rainer H Müller
Comparative study between the viscoelastic behaviors of different lipid nanoparticle formulations.
Journal of cosmetic science 2004;55(5):463-71.
2004: Carsten Rudolph; Ulrike Schillinger; Aurora Ortiz; Kerstin Tabatt; Christian Plank; Rainer H Müller; Joseph Rosenecker
Application of novel solid lipid nanoparticle (SLN)-gene vector formulations based on a dimeric HIV-1 TAT-peptide in vitro and in vivo.
Pharmaceutical research 2004;21(9):1662-9.
2004: Carsten Olbrich; Nadja Schöler; Kerstin Tabatt; Oliver Kayser; Rainer H Müller
Cytotoxicity studies of Dynasan 114 solid lipid nanoparticles (SLN) on RAW 264.7 macrophages-impact of phagocytosis on viability and cytokine production.
The Journal of pharmacy and pharmacology 2004;56(7):883-91.
2004: Eliana B. Souto; Sylvia A Wissing; CM Barbosa; Rainer H Müller
Evaluation of the physical stability of SLN and NLC before and after incorporation into hydrogel formulations.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(1):83-90.
2004: Kerstin Tabatt; Carsten Kneuer; Mohammad Sameti; Carsten Olbrich; Rainer H Müller; Claus-Michael Lehr; Udo Bakowsky
Transfection with different colloidal systems: comparison of solid lipid nanoparticles and liposomes.
Journal of controlled release : official journal of the Controlled Release Society 2004;97(2):321-32.
2004: Eliana B. Souto; Sylvia A Wissing; CM Barbosa; Rainer H Müller
Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery.
International journal of pharmaceutics 2004;278(1):71-7.
2004: Carsten Olbrich; Andrea Gessner; Werner Schröder; Oliver Kayser; Rainer H Müller
Lipid-drug conjugate nanoparticles of the hydrophilic drug diminazene-cytotoxicity testing and mouse serum adsorption.
Journal of controlled release : official journal of the Controlled Release Society 2004;96(3):425-35.
2004: Rainer H Müller; Cornelia M Keck
Drug delivery to the brain--realization by novel drug carriers.
Journal of nanoscience and nanotechnology 2004;4(5):471-83.
2004: Aslihan Akkar; Pawel Namsolleck; Michael Blaut; Rainer H Müller
Solubilizing poorly soluble antimycotic agents by emulsification via a solvent-free process.
AAPS PharmSciTech 2004;5(1):E24.
2004: Sylvia A Wissing; Rainer H Müller; Lars Manthei; Christian Mayer
Structural characterization of Q10-loaded solid lipid nanoparticles by NMR spectroscopy.
Pharmaceutical research 2004;21(3):400-5.
2004: Kerstin Tabatt; Mohammad Sameti; Carsten Olbrich; Rainer H Müller; Claus-Michael Lehr
Effect of cationic lipid and matrix lipid composition on solid lipid nanoparticle-mediated gene transfer.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;57(2):155-62.
2004: Rainer H Müller; Sven Schmidt; I Buttle; Aslihan Akkar; J Schmitt; S Brömer
SolEmuls-novel technology for the formulation of i.v. emulsions with poorly soluble drugs.
International journal of pharmaceutics 2004;269(2):293-302.
2004: Torsten M Göppert; Rainer H Müller
Alternative sample preparation prior to two-dimensional electrophoresis protein analysis on solid lipid nanoparticles.
Electrophoresis 2004;25(1):134-40.
2003: Adrian Peter Funke; Clemens Günther; Rainer H Müller; Ralph Lipp
Development of matrix patches for transdermal delivery of a highly lipophilic antiestrogen.
Drug development and industrial pharmacy 2003;29(7):785-93.
2003: Sylvia A Wissing; Rainer H Müller
The influence of solid lipid nanoparticles on skin hydration and viscoelasticity--in vivo study.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2003;56(1):67-72.
2003: Aslihan Akkar; Rainer H Müller
Intravenous itraconazole emulsions produced by SolEmuls technology.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2003;56(1):29-36.
2003: Andrea Gessner; Antje Lieske; Bernd-R Paulke; Rainer H Müller
Functional groups on polystyrene model nanoparticles: influence on protein adsorption.
Journal of biomedical materials research. Part A 2003;65(3):319-26.
2003: Torsten M Göppert; Rainer H Müller
Plasma protein adsorption of Tween 80- and poloxamer 188-stabilized solid lipid nanoparticles.
Journal of drug targeting 2003;11(4):225-31.
2003: Aslihan Akkar; Rainer H Müller
Formulation of intravenous carbamazepine emulsions by SolEmuls technology.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2003;55(3):305-12.
2003: Carsten Rudolph; Christian Plank; James Lausier; Ulrike Schillinger; Rainer H Müller; Joseph Rosenecker
Oligomers of the arginine-rich motif of the HIV-1 TAT protein are capable of transferring plasmid DNA into cells.
The Journal of biological chemistry 2003;278(13):11411-8.
2003: Sylvia A Wissing; Rainer H Müller
Cosmetic applications for solid lipid nanoparticles (SLN).
International journal of pharmaceutics 2003;254(1):65-8.
2003: Sven Schmidt; Rainer H Müller
Plasma protein adsorption patterns on surfaces of Amphotericin B-containing fat emulsions.
International journal of pharmaceutics 2003;254(1):3-5.
2003: Joseph Rosenecker; S Naundorf; Soeren Gersting; R W Hauck; A Gessner; Petra Nicklaus; Rainer H Müller; Carsten Rudolph
Interaction of bronchoalveolar lavage fluid with polyplexes and lipoplexes: analysing the role of proteins and glycoproteins.
The journal of gene medicine 2003;5(1):49-60.
2002: Rainer H Müller; M Radtke; Sylvia A Wissing
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations.
Advanced drug delivery reviews 2002;54 Suppl 1():S131-55.
2002: Rainer H Müller; M Radtke; Sylvia A Wissing
Nanostructured lipid matrices for improved microencapsulation of drugs.
International journal of pharmaceutics 2002;242(1-2):121-8.
2002: Carsten Olbrich; Andrea Gessner; Oliver Kayser; Rainer H Müller
Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate.
Journal of drug targeting 2002;10(5):387-96.
2002: Adrian Peter Funke; Clemens Günther; Rainer H Müller; Ralph Lipp
In-vitro release and transdermal fluxes of a highly lipophilic drug and of enhancers from matrix TDS.
Journal of controlled release : official journal of the Controlled Release Society 2002;82(1):63-70.
2002: Carsten Olbrich; Rainer H Müller; Kerstin Tabatt; Oliver Kayser; Christoph Schulze; Rüdiger Schade
Stable biocompatible adjuvants--a new type of adjuvant based on solid lipid nanoparticles: a study on cytotoxicity, compatibility and efficacy in chicken.
Alternatives to laboratory animals : ATLA 2002;30(4):443-58.
2002: Sylvia A Wissing; Rainer H Müller
Solid lipid nanoparticles as carrier for sunscreens: in vitro release and in vivo skin penetration.
Journal of controlled release : official journal of the Controlled Release Society 2002;81(3):225-33.
2002: Kathrin Lind; Mayk Kresse; Nils Debus; Rainer H Müller
A novel formulation for superparamagnetic iron oxide (SPIO) particles enhancing MR lymphography: comparison of physicochemical properties and the in vivo behaviour.
Journal of drug targeting 2002;10(3):221-30.
2002: Adrian Peter Funke; Roman Schiller; Hans W Motzkus; Clemens Günther; Rainer H Müller; Ralph Lipp
Transdermal delivery of highly lipophilic drugs: in vitro fluxes of antiestrogens, permeation enhancers, and solvents from liquid formulations.
Pharmaceutical research 2002;19(5):661-8.
2002: Rainer H Müller; Claudia Jacobs
Buparvaquone mucoadhesive nanosuspension: preparation, optimisation and long-term stability.
International journal of pharmaceutics 2002;237(1-2):151-61.
2002: Carsten Olbrich; Oliver Kayser; Rainer H Müller
Lipase degradation of Dynasan 114 and 116 solid lipid nanoparticles (SLN)--effect of surfactants, storage time and crystallinity.
International journal of pharmaceutics 2002;237(1-2):119-28.
2002: A Lippacher; Rainer H Müller; Karsten Mäder
Semisolid SLN dispersions for topical application: influence of formulation and production parameters on viscoelastic properties.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2002;53(2):155-60.
2002: Claudia Jacobs; Rainer H Müller
Production and characterization of a budesonide nanosuspension for pulmonary administration.
Pharmaceutical research 2002;19(2):189-94.
2002: Nadja Schöler; Helmut Hahn; Rainer H Müller; Oliver Liesenfeld
Effect of lipid matrix and size of solid lipid nanoparticles (SLN) on the viability and cytokine production of macrophages.
International journal of pharmaceutics 2002;231(2):167-76.
2002: S Harnisch; R Schuhmann; J F Harnisch; Rainer H Müller
Differences in the coalescence kinetics of fat emulsions in dependence on the amount of fat and age.
Die Pharmazie 2002;57(1):54-8.
2002: Carsten Rudolph; Rainer H Müller; Joseph Rosenecker
Jet nebulization of PEI/DNA polyplexes: physical stability and in vitro gene delivery efficiency.
The journal of gene medicine 2002;4(1):66-74.
2001: Carsten Olbrich; Udo Bakowsky; Claus-Michael Lehr; Rainer H Müller; Carsten Kneuer
Cationic solid-lipid nanoparticles can efficiently bind and transfect plasmid DNA.
Journal of controlled release : official journal of the Controlled Release Society 2001;77(3):345-55.
2001: Sylvia A Wissing; Rainer H Müller
Solid lipid nanoparticles (SLN)--a novel carrier for UV blockers.
Die Pharmazie 2001;56(10):783-6.
2001: K Lind; Mayk Kresse; Rainer H Müller
Comparison of protein adsorption patterns onto differently charged hydrophilic superparamagnetic iron oxide particles obtained in vitro and ex vivo.
Electrophoresis 2001;22(16):3514-21.
2001: K Lindl; Mayk Kresse; Rainer H Müller
Evaluation of desorption of proteins adsorbed to hydrophilic surfaces by two-dimensional electrophoresis.
Proteomics 2001;1(9):1059-66.
2001: E Zimmermann; Rainer H Müller
Electrolyte- and pH-stabilities of aqueous solid lipid nanoparticle (SLN) dispersions in artificial gastrointestinal media.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2001;52(2):203-10.
2001: Sylvia A Wissing; Rainer H Müller
A novel sunscreen system based on tocopherol acetate incorporated into solid lipid nanoparticles.
International journal of cosmetic science 2001;23(4):233-43.
2001: KP Krause; Rainer H Müller
Production of aqueous shellac dispersions by high pressure homogenisation.
International journal of pharmaceutics 2001;223(1-2):89-92.
2001: Nadja Schöler; Carsten Olbrich; Kerstin Tabatt; Rainer H Müller; Helmut Hahn; Oliver Liesenfeld
Surfactant, but not the size of solid lipid nanoparticles (SLN) influences viability and cytokine production of macrophages.
International journal of pharmaceutics 2001;221(1-2):57-67.
2001: Nadja Schöler; K Krause; Oliver Kayser; Rainer H Müller; Klaus Borner; Helmut Hahn; Oliver Liesenfeld
Atovaquone nanosuspensions show excellent therapeutic effect in a new murine model of reactivated toxoplasmosis.
Antimicrobial agents and chemotherapy 2001;45(6):1771-9.
2001: Rainer H Müller; Claudia Jacobs; Oliver Kayser
Nanosuspensions as particulate drug formulations in therapy. Rationale for development and what we can expect for the future.
Advanced drug delivery reviews 2001;47(1):3-19.
2001: Andrea Gessner; Carsten Olbrich; Werner Schröder; Oliver Kayser; Rainer H Müller
The role of plasma proteins in brain targeting: species dependent protein adsorption patterns on brain-specific lipid drug conjugate (LDC) nanoparticles.
International journal of pharmaceutics 2001;214(1-2):87-91.
2001: KP Krause; Rainer H Müller
Production and characterisation of highly concentrated nanosuspensions by high pressure homogenisation.
International journal of pharmaceutics 2001;214(1-2):21-4.
2001: A Lippacher; Rainer H Müller; Karsten Mäder
Preparation of semisolid drug carriers for topical application based on solid lipid nanoparticles.
International journal of pharmaceutics 2001;214(1-2):9-12.
2001: Claudia Jacobs; Oliver Kayser; Rainer H Müller
Production and characterisation of mucoadhesive nanosuspensions for the formulation of bupravaquone.
International journal of pharmaceutics 2001;214(1-2):3-7.
2000: K Thode; Rainer H Müller; Mayk Kresse
Two-time window and multiangle photon correlation spectroscopy size and zeta potential analysis--highly sensitive rapid assay for dispersion stability.
Journal of pharmaceutical sciences 2000;89(10):1317-24.
2000: Nadja Schöler; E Zimmermann; U Katzfey; Helmut Hahn; Rainer H Müller; Oliver Liesenfeld
Effect of solid lipid nanoparticles (SLN) on cytokine production and the viability of murine peritoneal macrophages.
Journal of microencapsulation 2000;17(5):639-50.
2000: Carsten Rudolph; James Lausier; S Naundorf; Rainer H Müller; Joseph Rosenecker
In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers.
The journal of gene medicine 2000;2(4):269-78.
2000: Andrea Gessner; Bernd-R Paulke; Rainer H Müller
Analysis of plasma protein adsorption onto polystyrene particles by two-dimensional electrophoresis: comparison of sample application and isoelectric focusing techniques.
Electrophoresis 2000;21(12):2438-42.
2000: Rainer H Müller; Karsten Mäder; SH Gohla
Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2000;50(1):161-77.
2000: Andrea Gessner; R Waicz; Antje Lieske; Bernd-R Paulke; Karsten Mäder; Rainer H Müller
Nanoparticles with decreasing surface hydrophobicities: influence on plasma protein adsorption.
International journal of pharmaceutics 2000;196(2):245-9.
2000: Nadja Schöler; E Zimmermann; U Katzfey; Helmut Hahn; Rainer H Müller; Oliver Liesenfeld
Preserved solid lipid nanoparticles (SLN) at low concentrations do cause neither direct nor indirect cytotoxic effects in peritoneal macrophages.
International journal of pharmaceutics 2000;196(2):235-9.
2000: K Seehof; Mayk Kresse; Karsten Mäder; Rainer H Müller
Interactions of nanoparticles with body proteins--improvement of 2D-PAGE-analysis by internal standard.
International journal of pharmaceutics 2000;196(2):231-4.
2000: A Lippacher; Rainer H Müller; Karsten Mäder
Investigation on the viscoelastic properties of lipid based colloidal drug carriers.
International journal of pharmaceutics 2000;196(2):227-30.
2000: E Zimmermann; Rainer H Müller; Karsten Mäder
Influence of different parameters on reconstitution of lyophilized SLN.
International journal of pharmaceutics 2000;196(2):211-3.
2000: S Liedtke; Sylvia A Wissing; Rainer H Müller; Karsten Mäder
Influence of high pressure homogenisation equipment on nanodispersions characteristics.
International journal of pharmaceutics 2000;196(2):183-5.
2000: KP Krause; Oliver Kayser; Karsten Mäder; R Gust; Rainer H Müller
Heavy metal contamination of nanosuspensions produced by high-pressure homogenisation.
International journal of pharmaceutics 2000;196(2):169-72.
2000: Claudia Jacobs; Oliver Kayser; Rainer H Müller
Nanosuspensions as a new approach for the formulation for the poorly soluble drug tarazepide.
International journal of pharmaceutics 2000;196(2):161-4.
2000: M J Grau; Oliver Kayser; Rainer H Müller
Nanosuspensions of poorly soluble drugs--reproducibility of small scale production.
International journal of pharmaceutics 2000;196(2):155-9.
2000: K Peters; S Leitzke; J E Diederichs; Klaus Borner; Helmut Hahn; Rainer H Müller; S Ehlers
Preparation of a clofazimine nanosuspension for intravenous use and evaluation of its therapeutic efficacy in murine Mycobacterium avium infection.
The Journal of antimicrobial chemotherapy 2000;45(1):77-83.
2000: S Harnisch; Rainer H Müller
Adsorption kinetics of plasma proteins on oil-in-water emulsions for parenteral nutrition.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2000;49(1):41-6.
1999: A Dingler; R P Blum; H Niehus; Rainer H Müller; SH Gohla
Solid lipid nanoparticles (SLN/Lipopearls)--a pharmaceutical and cosmetic carrier for the application of vitamin E in dermal products.
Journal of microencapsulation 1999;16(6):751-67.
1999: S Anger; K Caldwell; H Niehus; Rainer H Müller
High resolution size determination of 20 nm colloidal gold particles by SedFFF.
Pharmaceutical research 1999;16(11):1743-7.
1999: M Lück; W Schröder; Bernd-R Paulke; T Blunk; Rainer H Müller
Complement activation by model drug carriers for intravenous application: determination by two-dimensional electrophoresis.
Biomaterials 1999;20(21):2063-8.
1999: K Peters; Rainer H Müller; D Q Craig
An investigation into the distribution of lecithins in nanosuspension systems using low frequency dielectric spectroscopy.
International journal of pharmaceutics 1999;184(1):53-61.
1999: Carsten Olbrich; Rainer H Müller
Enzymatic degradation of SLN-effect of surfactant and surfactant mixtures.
International journal of pharmaceutics 1999;180(1):31-9.
1999: C Freitas; Rainer H Müller
Correlation between long-term stability of solid lipid nanoparticles (SLN) and crystallinity of the lipid phase.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1999;47(2):125-32.
1999: Klaus Borner; H Hartwig; S Leitzke; Helmut Hahn; Rainer H Müller; S Ehlers
HPLC determination of clofazimine in tissues and serum of mice after intravenous administration of nanocrystalline or liposomal formulations.
International journal of antimicrobial agents 1999;11(1):75-9.
1999: C Freitas; Rainer H Müller
Stability determination of solid lipid nanoparticles (SLN) in aqueous dispersion after addition of electrolyte.
Journal of microencapsulation 1999;16(1):59-71.
1998: M Lück; K F Pistel; Y X Li; T Blunk; Rainer H Müller; T Kissel
Plasma protein adsorption on biodegradable microspheres consisting of poly(D,L-lactide-co-glycolide), poly(L-lactide) or ABA triblock copolymers containing poly(oxyethylene). Influence of production method and polymer composition.
Journal of controlled release : official journal of the Controlled Release Society 1998;55(2-3):107-20.
1998: M Lück; Bernd-R Paulke; W Schröder; T Blunk; Rainer H Müller
Analysis of plasma protein adsorption on polymeric nanoparticles with different surface characteristics.
Journal of biomedical materials research 1998;39(3):478-85.
1998: S Harnisch; Rainer H Müller
Plasma protein adsorption patterns on emulsions for parenteral administration: establishment of a protocol for two-dimensional polyacrylamide electrophoresis.
Electrophoresis 1998;19(2):349-54.
1998: K Thode; M Lück; W Schröder; T Blunk; Rainer H Müller; Mayk Kresse
The influence of the sample preparation on plasma protein adsorption patterns on polysaccharide-stabilized iron oxide particles and N-terminal microsequencing of unknown proteins.
Journal of drug targeting 1998;5(6):459-69.
1998: W E Bucke; S Leitzke; J E Diederichs; Klaus Borner; Helmut Hahn; S Ehlers; Rainer H Müller
Surface-modified amikacin-liposomes: organ distribution and interaction with plasma proteins.
Journal of drug targeting 1998;5(2):99-108.
1997: M Lück; W Schröder; S Harnisch; K Thode; T Blunk; Bernd-R Paulke; Mayk Kresse; Rainer H Müller
Identification of plasma proteins facilitated by enrichment on particulate surfaces: analysis by two-dimensional electrophoresis and N-terminal microsequencing.
Electrophoresis 1997;18(15):2961-7.
1997: K Thode; M Lück; Wolfhard Semmler; Rainer H Müller; Mayk Kresse
Determination of plasma protein adsorption on magnetic iron oxides: sample preparation.
Pharmaceutical research 1997;14(7):905-10.
1997: Rainer H Müller; D Rühl; S Runge; Kai Schulze-Forster; Wolfgang Mehnert
Cytotoxicity of solid lipid nanoparticles as a function of the lipid matrix and the surfactant.
Pharmaceutical research 1997;14(4):458-62.
1997: K Thode; M Lück; W Schröder; Wolfhard Semmler; T Blunk; Rainer H Müller; Mayk Kresse
The influence of the sample preparation on plasma protein adsorption patterns on polysaccharide-stabilized iron oxide particles and N-terminal microsequencing of unknown proteins.
Journal of drug targeting 1997;5(1):35-43.
1997: Rainer H Müller; D Rühl; M Lück; Bernd-R Paulke
Influence of fluorescent labelling of polystyrene particles on phagocytic uptake, surface hydrophobicity, and plasma protein adsorption.
Pharmaceutical research 1997;14(1):18-24.
1996: H Hedeman; M Lück; T Blunk; Sven Frokjaer; Rainer H Müller
Fat emulsions based on structured lipids (1,3-specific triglycerides): an investigation of the in vitro interaction with plasma proteins.
Clinical nutrition (Edinburgh, Scotland) 1996;15(4):175-8.
1996: Rainer H Müller; S Maassen; H Weyhers; Wolfgang Mehnert
Phagocytic uptake and cytotoxicity of solid lipid nanoparticles (SLN) sterically stabilized with poloxamine 908 and poloxamer 407.
Journal of drug targeting 1996;4(3):161-70.
1993: T Blunk; D F Hochstrasser; jean-charles sanchez; Bernd W Müller; Rainer H Müller
Colloidal carriers for intravenous drug targeting: plasma protein adsorption patterns on surface-modified latex particles evaluated by two-dimensional polyacrylamide gel electrophoresis.
Electrophoresis 1993;14(12):1382-7.
1991: Rainer H Müller; S Heinemann
Photon correlation spectroscopy and zeta potential characterization of model particles and colloidal drug carriers--essential information for the interpretation of cell culture studies.
Biochemical Society transactions 1991;19(2):502.
1984: B W Müller; Rainer H Müller
Particle size distributions and particle size alterations in microemulsions.
Journal of pharmaceutical sciences 1984;73(7):919-22.
1984: B W Müller; Rainer H Müller
Particle size analysis of latex suspensions and microemulsions by photon correlation spectroscopy.
Journal of pharmaceutical sciences 1984;73(7):915-8.