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James Mullins

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Morgane Rolland; J Victor Swain; Dylan H Westfall; Peter B Gilbert; Moon Kim; Erinn C Lanxon-Cookson; Brendan B Larsen; Siriphan Manocheewa; James I Mullins
HIV-1 conserved-element vaccines: relationship between sequence conservation and replicative capacity.
Yi Liu; Jan McClure; Ushnal Rao; J Victor Swain; Lennie Chen; Sarah Holte; Moon Kim; Philip Konopa; Erinn Lanxon-Cookson; James I Mullins
A sensitive real-time PCR based assay to estimate the impact of amino acid substitutions on the competitive replication fitness of human immunodeficiency virus type 1 in cell culture.
Thor A Wagner; Jen L McKernan; James I Mullins; Ken A Tapia; Nicole H Tobin; Lisa M Frenkel
An increasing proportion of monotypic HIV-1 DNA sequences during antiretroviral treatment suggests proliferation of HIV-infected cells.

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2013: Morgane Rolland; J Victor Swain; Dylan H Westfall; Peter B Gilbert; Moon Kim; Erinn C Lanxon-Cookson; Brendan B Larsen; Siriphan Manocheewa; James I Mullins
HIV-1 conserved-element vaccines: relationship between sequence conservation and replicative capacity.
Journal of virology 2013;87(10):5461-7.
2013: Yi Liu; Jan McClure; Ushnal Rao; J Victor Swain; Lennie Chen; Sarah Holte; Moon Kim; Philip Konopa; Erinn Lanxon-Cookson; James I Mullins
A sensitive real-time PCR based assay to estimate the impact of amino acid substitutions on the competitive replication fitness of human immunodeficiency virus type 1 in cell culture.
Journal of virological methods 2013;189(1):157-66.
2013: Thor A Wagner; Jen L McKernan; James I Mullins; Ken A Tapia; Nicole H Tobin; Lisa M Frenkel
An increasing proportion of monotypic HIV-1 DNA sequences during antiretroviral treatment suggests proliferation of HIV-infected cells.
Journal of virology 2013;87(3):1770-8.
2013: Jairam R Lingappa; James I Mullins; Katherine K Thomas; Anna Wald; Jared M Baeten; Mary S Campbell; Connie Celum; Guy de Bruyn; Carey Farquhar; Kenneth H Fife; James P Hughes; Saidi H Kapiga
Partner characteristics predicting HIV-1 set point in sexually acquired HIV-1 among African seroconverters.
AIDS research and human retroviruses 2013;29(1):164-71.
2012: Joshua T Herbeck; Lisa P Jacobson; bruno ledergerber; Brandon S Maust; Viktor Müller; James I Mullins; Carlo Torti; Simona Di Giambenedetto; Luuk Gras; Huldrych Günthard; Geoffrey S Gottlieb
Is the virulence of HIV changing? A meta-analysis of trends in prognostic markers of HIV disease progression and transmission.
AIDS (London, England) 2012;26(2):193-205.
2012: Robert A Smith; Papa Salif Sow; Geoffrey S Gottlieb; Brad Church; Matthew Coyne; Alexandra Hernandez; James I Mullins; Charlotte Pan; Kara Parker; Dana N Raugi
Three main mutational pathways in HIV-2 lead to high-level raltegravir and elvitegravir resistance: implications for emerging HIV-2 treatment regimens.
PloS one 2012;7(9):e45372.
2011: Joshua T Herbeck; Yi Liu; Brandon S Maust; M Juliana McElrath; Angela McKay; Sherry McLaughlin; John McNevin; Brian Birditt; Ann C Collier; Wenjie Deng; Kurt Diem; Indira Genowati; Dana Raugi; Morgane Rolland; Stephanie Sorensen; Joanne D Stekler; Julia N Stoddard; Kim Wong; Hong Zhao; James I Mullins
Demographic processes affect HIV-1 evolution in primary infection before the onset of selective processes.
Journal of virology 2011;85(15):7523-34.
2011: Jared M Baeten; Erin Kahle; Jaisri R Lingappa; Robert W Coombs; Sinead Delany-Moretlwe; Edith Nakku-Joloba; Nelly R Mugo; Anna Wald; Lawrence Corey; Deborah Donnell; Mary S Campbell; James I Mullins; Connie Celum
Genital HIV-1 RNA predicts risk of heterosexual HIV-1 transmission.
Science translational medicine 2011;3(77):77ra29.
2011: Jaisri R Lingappa; M Juliana McElrath; James I Mullins; Edith Nakku-Joloba; Slave Petrovski; Kevin Shianna; Katherine K Thomas; Anna Wald; Jared M Baeten; Connie Celum; Guy de Bruyn; Deborah Donnell; Max Essex; Carey Farquhar; Jacques Fellay; David Goldstein; Bart Haynes; Erin Kahle; James N Kiarie
Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure.
PloS one 2011;6(12):e28632.
2011: Geoffrey S Gottlieb; Stephen E Hawes; Moon Kim; Nancy B Kiviat; Airin Lam; Paul Lu; James I Mullins; Dana N Raugi; Fatima Sall; Robert A Smith; Alison K Starling; Joshua Stern; Macoumba Toure; Fatou Traore; Kim G Wong; Selly Ba; Stephen L Cherne; Ndeye Mery Dia Badiane
HIV-2 integrase variation in integrase inhibitor-naïve adults in Senegal, West Africa.
PloS one 2011;6(7):e22204.
2011: Morgane Rolland; Nicole Frahm; David C Nickle; Nebojsa Jojic; Wenjie Deng; Todd M Allen; Christian Brander; David E Heckerman; James I Mullins
Increased breadth and depth of cytotoxic T lymphocytes responses against HIV-1-B Nef by inclusion of epitope variant sequences.
PloS one 2011;6(3):e17969.
2011: Mary S Campbell; James I Mullins; James P Hughes; Connie Celum; Kim G Wong; Dana N Raugi; Stefanie Sorensen; Julia N Stoddard; Hong Zhao; Wenjie Deng; Erin Kahle; Dana D Panteleeff; Jared M Baeten; Francine E McCutchan; Jan Albert; Thomas Leitner; Anna Wald; Lawrence Corey; Jaisri R Lingappa
Viral linkage in HIV-1 seroconverters and their partners in an HIV-1 prevention clinical trial.
PloS one 2011;6(3):e16986.
2011: Yi Liu; John P McNevin; Sarah Holte; M Juliana McElrath; James I Mullins
Dynamics of viral evolution and CTL responses in HIV-1 infection.
PloS one 2011;6(1):e15639.
2011: James I Mullins; Laura Heath; James P Hughes; Jessica Kicha; Sheila Styrchak; Kim G Wong; Ushnal Rao; Alexis Hansen; Kevin S Harris; Jean-Pierre Laurent; Deyu Li; Jeffrey H Simpson; John M Essigmann; Lawrence A Loeb; Jeffrey Parkins
Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461.
PloS one 2011;6(1):e15135.
2010: Laura Heath; Lisa M Frenkel; Brian Thomas Foley; James I Mullins
Comment on "The origins of sexually transmitted HIV among men who have sex with men".
Science translational medicine 2010;2(50):50le1; author reply 50lr1.
2010: Joshua T Herbeck; Geoffrey S Gottlieb; Cheryl A Winkler; George W Nelson; Ping An; Brandon S Maust; Kim G Wong; Jennifer L Troyer; James J Goedert; Bailey D Kessing; Roger Detels; Steven M Wolinsky; Jeremy Martinson; Susan Buchbinder; Gregory D Kirk; Lisa P Jacobson; Joseph B Margolick; Richard A Kaslow; Stephen J O'Brien; James I Mullins
Multistage genomewide association study identifies a locus at 1q41 associated with rate of HIV-1 disease progression to clinical AIDS.
The Journal of infectious diseases 2010;201(4):618-26.
2010: Marcel E Curlin; Rafael Zioni; Stephen E Hawes; Yi Liu; Wenjie Deng; Geoffrey S Gottlieb; Tuofu Zhu; James I Mullins
HIV-1 envelope subregion length variation during disease progression.
PLoS pathogens 2010;6(12):e1001228.
2010: Xiao-Li Huang; Zheng Fan; Luann Borowski; Robbie B Mailliard; Morgane Rolland; James I Mullins; Richard D Day; Charles Rinaldo
Dendritic cells reveal a broad range of MHC class I epitopes for HIV-1 in persons with suppressed viral load on antiretroviral therapy.
PloS one 2010;5(9):e12936.
2010: Morgane Rolland; Jonathan M Carlson; Siriphan Manocheewa; J Victor Swain; Erinn Lanxon-Cookson; Wenjie Deng; Christine M Rousseau; Dana N Raugi; Gerald Learn; Brandon S Maust; Hoosen Coovadia; Thumbi Ndung'u; Philip J R Goulder; Bruce D Walker; Christian Brander; David E Heckerman; James I Mullins
Amino-acid co-variation in HIV-1 Gag subtype C: HLA-mediated selection pressure and compensatory dynamics.
PloS one 2010;5(9):.
2010: Laura Heath; Susan Conway; Laura Jones; Katherine Semrau; Kyle Nakamura; Jan Walter; W Don Decker; Jason Hong; Thomas Chen; Marintha Heil; Moses Sinkala; Chipepo Kankasa; Donald M Thea; Louise Kuhn; James I Mullins; Grace M Aldrovandi
Restriction of HIV-1 genotypes in breast milk does not account for the population transmission genetic bottleneck that occurs following transmission.
PloS one 2010;5(4):e10213.
2009: Yi Liu; John McNevin; Morgane Rolland; Hong Zhao; Wenjie Deng; Janine Maenza; Claire E Stevens; Ann C Collier; M Juliana McElrath; James I Mullins
Conserved HIV-1 epitopes continuously elicit subdominant cytotoxic T-lymphocyte responses.
The Journal of infectious diseases 2009;200(12):1825-33.
2009: Uma Malhotra; J Nolin; Helen Horton; Fusheng Li; L Corey; James I Mullins; M Juliana McElrath
Functional properties and epitope characteristics of T-cells recognizing natural HIV-1 variants.
Vaccine 2009;27(48):6678-87.
2009: Yi Liu; Amanda Woodward; Haiying Zhu; Thomas Andrus; John McNevin; Jean Lee; James I Mullins; Lawrence Corey; M Juliana McElrath; Tuofu Zhu
Preinfection human immunodeficiency virus (HIV)-specific cytotoxic T lymphocytes failed to prevent HIV type 1 infection from strains genetically unrelated to viruses in long-term exposed partners.
Journal of virology 2009;83(20):10821-9.
2009: Ryan M Troyer; John McNevin; Yi Liu; Shao Chong Zhang; Randall W Krizan; Awet Abraha; Denis M Tebit; Hong Zhao; Santiago Avila; Michael A Lobritz; M Juliana McElrath; Sylvie Le Gall; James I Mullins; Eric J Arts
Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response.
PLoS pathogens 2009;5(4):e1000365.
2009: Christine M Rousseau; David W Lockhart; Jennifer Listgarten; Stephen N Maley; Carl Kadie; Gerald Learn; David C Nickle; David E Heckerman; Wenjie Deng; Christian Brander; Thumbi Ndung'u; Hoosen Coovadia; Philip J R Goulder; Bette T Korber; Bruce D Walker; James I Mullins
Rare HLA drive additional HIV evolution compared to more frequent alleles.
AIDS research and human retroviruses 2009;25(3):297-303.
2009: Geoffrey S Gottlieb; Ndeye Mery Dia Badiane; Stephen E Hawes; Louise Fortes; Macoumba Toure; Cheikh T Ndour; Alison K Starling; Fatou Traore; Fatima Sall; Kim G Wong; Stephen L Cherne; Donovan J Anderson; Stefanie A Dye; Robert Smith; James I Mullins; Nancy B Kiviat; Papa Salif Sow
Emergence of multiclass drug-resistance in HIV-2 in antiretroviral-treated individuals in Senegal: implications for HIV-2 treatment in resouce-limited West Africa.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009;48(4):476-83.
2009: Laura Heath; Alan Fox; Jan McClure; Kurt Diem; Angélique B van 't Wout; Hong Zhao; David R Park; Jeffrey T Schouten; Homer L Twigg; Lawrence Corey; James I Mullins; John E Mittler
Evidence for limited genetic compartmentalization of HIV-1 between lung and blood.
PloS one 2009;4(9):e6949.
2009: Joshua T Herbeck; Geoffrey S Gottlieb; Kim Wong; Roger Detels; John P Phair; Charles Rinaldo; Lisa P Jacobson; Joseph B Margolick; James I Mullins
Fidelity of SNP array genotyping using Epstein Barr virus-transformed B-lymphocyte cell lines: implications for genome-wide association studies.
PloS one 2009;4(9):e6915.
2008: Jonathan M Carlson; Zabrina L Brumme; Christine M Rousseau; Chanson J Brumme; Philippa Matthews; Carl Kadie; James I Mullins; Bruce D Walker; P Richard Harrigan; Philip J R Goulder; David Heckerman
Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.
PLoS computational biology 2008;4(11):e1000225.
2008: Philippa C Matthews; Andrew Prendergast; Alasdair Leslie; Hayley Crawford; Rebecca Payne; Christine M Rousseau; Morgane Rolland; Isobella Honeyborne; Jonathan Carlson; Carl Kadie; Christian Brander; Karen Bishop; Nonkululeko Mlotshwa; James I Mullins; Hoosen Coovadia; Thumbi Ndung'u; Bruce D Walker; David Heckerman; Philip J R Goulder
Central role of reverting mutations in HLA associations with human immunodeficiency virus set point.
Journal of virology 2008;82(17):8548-59.
2008: Christine M Rousseau; Marcus G Daniels; Jonathan M Carlson; Carl Kadie; Hayley Crawford; Andrew Prendergast; Philippa Matthews; Rebecca Payne; Morgane Rolland; Dana N Raugi; Brandon S Maust; Gerald Learn; David C Nickle; Hoosen Coovadia; Thumbi Ndung'u; Nicole Frahm; Christian Brander; Bruce D Walker; Philip J R Goulder; Tanmoy Bhattacharya; David E Heckerman; Bette T Korber; James I Mullins
HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load.
Journal of virology 2008;82(13):6434-46.
2008: Yi Liu; Marcel E Curlin; Kurt Diem; Hong Zhao; Ananta K Ghosh; Haiying Zhu; Amanda S Woodward; Janine Maenza; Claire E Stevens; Joanne Stekler; Ann C Collier; Indira Genowati; Wenjie Deng; Rafael Zioni; Lawrence Corey; Tuofu Zhu; James I Mullins
Env length and N-linked glycosylation following transmission of human immunodeficiency virus Type 1 subtype B viruses.
Virology 2008;374(2):229-33.
2008: Kurt Diem; David C Nickle; Alexis Motoshige; Alan Fox; Susan Ross; James I Mullins; Lawrence Corey; Robert W Coombs; John N Krieger
Male genital tract compartmentalization of human immunodeficiency virus type 1 (HIV).
AIDS research and human retroviruses 2008;24(4):561-71.
2008: Geoffrey S Gottlieb; Laura Heath; David C Nickle; Kim G Wong; Stephanie E Leach; Benjamin Jacobs; Surafel Gezahegne; Angélique B van 't Wout; Lisa P Jacobson; Joseph B Margolick; James I Mullins
HIV-1 variation before seroconversion in men who have sex with men: analysis of acute/early HIV infection in the multicenter AIDS cohort study.
The Journal of infectious diseases 2008;197(7):1011-5.
2008: Tae-Wook Chun; David C Nickle; J Shawn Justement; Jennifer H Meyers; Gregg Roby; Claire W Hallahan; Shyam Kottilil; Susan Moir; JoAnn M Mican; James I Mullins; Douglas J Ward; Joseph A Kovacs; Peter J Mannon; Anthony Fauci
Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy.
The Journal of infectious diseases 2008;197(5):714-20.
2008: Nicole Frahm; David C Nickle; Caitlyn H Linde; Daniel E Cohen; Rosario Zuñiga; Aldo Lucchetti; Timothy Roach; Bruce D Walker; Todd M Allen; Bette T Korber; James I Mullins; Christian Brander
Increased detection of HIV-specific T cell responses by combination of central sequences with comparable immunogenicity.
AIDS (London, England) 2008;22(4):447-56.
2008: Younong Xu; Haiying Zhu; Carrie K Wilcox; Angélique van't Wout; Thomas Andrus; Nicholas Llewellyn; Leonidas Stamatatos; James I Mullins; Lawrence Corey; Tuofu Zhu
Blood monocytes harbor HIV type 1 strains with diversified phenotypes including macrophage-specific CCR5 virus.
The Journal of infectious diseases 2008;197(2):309-18.
2008: David C Nickle; Nebojsa Jojic; David Heckerman; Vladimir Jojic; Darko Kirovski; Morgane Rolland; Sergei Kosakovsky Pond; James I Mullins
Comparison of immunogen designs that optimize peptide coverage: reply to Fischer et al.
PLoS computational biology 2008;4(1):e25.
2008: Joshua T Herbeck; Geoffrey S Gottlieb; Xiuhong Li; Zheng Hu; Roger Detels; John Phair; Charles Rinaldo; Lisa P Jacobson; Joseph B Margolick; James I Mullins
Lack of evidence for changing virulence of HIV-1 in North America.
PloS one 2008;3(2):e1525.
2008: Morgane Rolland; David Heckerman; Wenjie Deng; Christine M Rousseau; Hoosen Coovadia; Karen Bishop; Philip J R Goulder; Bruce D Walker; Christian Brander; James I Mullins
Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads.
PloS one 2008;3(1):e1424.
2008: Jianhong Cao; John McNevin; Matthew D McSweyn; Yi Liu; James I Mullins; M Juliana McElrath
Novel cytotoxic T-lymphocyte escape mutation by a three-amino-acid insertion in the human immunodeficiency virus type 1 p6Pol and p6Gag late domain associated with drug resistance.
Journal of virology 2008;82(1):495-502.
2007: Morgane Rolland; David C Nickle; James I Mullins
HIV-1 group M conserved elements vaccine.
PLoS pathogens 2007;3(11):e157.
2007: Yi Liu; John McNevin; Hong Zhao; Denis M Tebit; Ryan M Troyer; Matthew D McSweyn; Ananta K Ghosh; Daniel Shriner; Eric J Arts; M Juliana McElrath; James I Mullins
Evolution of human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitopes: fitness-balanced escape.
Journal of virology 2007;81(22):12179-88.
2007: Morgane Rolland; Christian Brander; David C Nickle; Joshua T Herbeck; Geoffrey S Gottlieb; Mary S Campbell; Brandon S Maust; James I Mullins
HIV-1 over time: fitness loss or robustness gain?
Nature reviews. Microbiology 2007;5(9):C1.
2007: Wenjie Deng; David C Nickle; Gerald Learn; Brandon Maust; James I Mullins
ViroBLAST: a stand-alone BLAST web server for flexible queries of multiple databases and user's datasets.
Bioinformatics (Oxford, England) 2007;23(17):2334-6.
2007: Geoffrey S Gottlieb; David C Nickle; Mark A Jensen; Kim G Wong; Richard A Kaslow; James Christopher Shepherd; Joseph B Margolick; James I Mullins
HIV type 1 superinfection with a dual-tropic virus and rapid progression to AIDS: a case report.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;45(4):501-9.
2007: Morgane Rolland; Mark A Jensen; David C Nickle; Jian Yan; Gerald Learn; Laura Heath; David Weiner; James I Mullins
Reconstruction and function of ancestral center-of-tree human immunodeficiency virus type 1 proteins.
Journal of virology 2007;81(16):8507-14.
2007: Hayley Crawford; Julia G Prado; Alasdair Leslie; Stéphane Hué; Isobella Honeyborne; Sharon Reddy; Mary van der Stok; Zenele Mncube; Christian Brander; Christine M Rousseau; James I Mullins; Richard A Kaslow; Paul A Goepfert; Susan Allen; Eric Hunter; Joseph Mulenga; Photini Kiepiela; Bruce D Walker; Philip J R Goulder
Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection.
Journal of virology 2007;81(15):8346-51.
2007: Tae-Wook Chun; J Shawn Justement; Susan Moir; Claire W Hallahan; Janine Maenza; James I Mullins; Ann C Collier; Lawrence Corey; Anthony Fauci
Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus.
The Journal of infectious diseases 2007;195(12):1762-4.
2007: Joshua T Herbeck; Frederick Lyagoba; Sarah W Moore; Nice Shindo; Benon Biryahwaho; Pontiano Kaleebu; James I Mullins
Prevalence and genetic diversity of HIV type 1 subtypes A and D in women attending antenatal clinics in Uganda.
AIDS research and human retroviruses 2007;23(5):755-60.
2007: Uma Malhotra; Fusheng Li; Jessica Nolin; Megan Allison; Hong Zhao; James I Mullins; Steven G Self; M Juliana McElrath
Enhanced detection of human immunodeficiency virus type 1 (HIV-1) Nef-specific T cells recognizing multiple variants in early HIV-1 infection.
Journal of virology 2007;81(10):5225-37.
2007: Christine M Rousseau; Gerald Learn; Tanmoy Bhattacharya; David C Nickle; David Heckerman; Senica Chetty; Christian Brander; Philip J R Goulder; Bruce D Walker; Photini Kiepiela; Bette T Korber; James I Mullins
Extensive intrasubtype recombination in South African human immunodeficiency virus type 1 subtype C infections.
Journal of virology 2007;81(9):4492-500.
2007: David C Nickle; Morgane Rolland; Mark A Jensen; Sergei L Kosakovsky Pond; Wenjie Deng; Mark Seligman; David Heckerman; James I Mullins; Nebojsa Jojic
Coping with viral diversity in HIV vaccine design.
PLoS computational biology 2007;3(4):e75.
2007: Isobella Honeyborne; Andrew Prendergast; Florencia Pereyra; Alasdair Leslie; Hayley Crawford; Rebecca Payne; Sharon Reddy; Karen Bishop; Eshia Stephany Moodley-Govender; Kriebashnie Nair; Mary van der Stok; Noel McCarthy; Christine M Rousseau; Marylyn M Addo; James I Mullins; Christian Brander; Photini Kiepiela; Bruce D Walker; Philip J R Goulder
Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes.
Journal of virology 2007;81(7):3667-72.
2007: Tanmoy Bhattacharya; Marcus Daniels; David Heckerman; Brian Foley; Nicole Frahm; Carl Kadie; Jonathan Carlson; Karina Yusim; Ben McMahon; Brian Gaschen; Simon Mallal; James I Mullins; David C Nickle; Joshua Herbeck; Christine M Rousseau; Gerald Learn; Toshiyuki Miura; Christian Brander; Bruce Walker; Bette Korber
Founder effects in the assessment of HIV polymorphisms and HLA allele associations.
Science (New York, N.Y.) 2007;315(5818):1583-6.
2007: Geoffrey S Gottlieb; Stephen E Hawes; David C Nickle; Joshua T Herbeck; Nancy B Kiviat; James I Mullins; Papa Salif Sow
Presenting plasma HIV RNA level and rate of CD4 T-cell decline.
JAMA : the journal of the American Medical Association 2007;297(8):805; author reply 806-7.
2007: Uma Malhotra; Jessica Nolin; James I Mullins; M Juliana McElrath
Comprehensive epitope analysis of cross-clade Gag-specific T-cell responses in individuals with early HIV-1 infection in the US epidemic.
Vaccine 2007;25(2):381-90.
2007: Morgane Rolland; David C Nickle; Wenjie Deng; Nicole Frahm; Christian Brander; Gerald Learn; David Heckerman; Nebojsa Jojic; Vladimir Jojic; Bruce D Walker; James I Mullins
Recognition of HIV-1 peptides by host CTL is related to HIV-1 similarity to human proteins.
PloS one 2007;2(9):e823.
2007: David C Nickle; Laura Heath; Mark A Jensen; Peter B Gilbert; James I Mullins; Sergei L Kosakovsky Pond
HIV-specific probabilistic models of protein evolution.
PloS one 2007;2(6):e503.
2007: Photini Kiepiela; Kholiswa Ngumbela; Christina Thobakgale; Danni Ramduth; Isobella Honeyborne; Eshia Stephany Moodley-Govender; Sharon Reddy; Chantal de Pierres; Zenele Mncube; Nompumelelo Mkhwanazi; Karen Bishop; Mary van der Stok; Kriebashnie Nair; Nasreen Khan; Hayley Crawford; Rebecca Payne; Alasdair Leslie; Julia G Prado; Andrew Prendergast; John Frater; Noel McCarthy; Christian Brander; Gerald Learn; David C Nickle; Christine M Rousseau; Hoosen Coovadia; James I Mullins; David Heckerman; Bruce D Walker; Philip J R Goulder
CD8+ T-cell responses to different HIV proteins have discordant associations with viral load.
Nature medicine 2007;13(1):46-53.
2006: Alasdair Leslie; David A Price; Pamela Mkhize; Karen Bishop; Almas Rathod; Cheryl Day; Hayley Crawford; Isobella Honeyborne; Tedi E Asher; Graz Luzzi; Anne Edwards; Christine M Rousseau; Christine M Rosseau; James I Mullins; Gareth Tudor-Williams; Vas Novelli; Christian Brander; Daniel C Douek; Photini Kiepiela; Bruce D Walker; Philip J R Goulder
Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4699-708.
2006: Yi Liu; John McNevin; Jianhong Cao; Hong Zhao; Indira Genowati; Kim Wong; Sherry McLaughlin; Matthew D McSweyn; Kurt Diem; Claire E Stevens; Janine Maenza; Hongxia He; David C Nickle; Daniel Shriner; Sarah Holte; Ann C Collier; Lawrence Corey; M Juliana McElrath; James I Mullins
Selection on the human immunodeficiency virus type 1 proteome following primary infection.
Journal of virology 2006;80(19):9519-29.
2006: Christine M Rousseau; Brian A Birditt; Angela R McKay; Julia N Stoddard; Tsan Chun Lee; Sherry McLaughlin; Sarah W Moore; Nice Shindo; Gerald Learn; Bette T Korber; Christian Brander; Philip J R Goulder; Photini Kiepiela; Bruce D Walker; James I Mullins
Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes.
Journal of virological methods 2006;136(1-2):118-25.
2006: Daniel Shriner; Yi Liu; David C Nickle; James I Mullins
Evolution of intrahost HIV-1 genetic diversity during chronic infection.
Evolution; international journal of organic evolution 2006;60(6):1165-76.
2006: Mark A Jensen; Mia Coetzer; Angélique B van 't Wout; Lynn Morris; James I Mullins
A reliable phenotype predictor for human immunodeficiency virus type 1 subtype C based on envelope V3 sequences.
Journal of virology 2006;80(10):4698-704.
2006: Javier Martinez-Picado; Julia G Prado; Elizabeth E Fry; Katja Pfafferott; Alasdair Leslie; Senica Chetty; Christina Thobakgale; Isobella Honeyborne; Hayley Crawford; Philippa Matthews; Tilly Pillay; Christine M Rousseau; James I Mullins; Christian Brander; Bruce D Walker; David I Stuart; Photini Kiepiela; Philip J R Goulder
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1.
Journal of virology 2006;80(7):3617-23.
2006: Yi Liu; James I Mullins; John E Mittler
Waiting times for the appearance of cytotoxic T-lymphocyte escape mutants in chronic HIV-1 infection.
Virology 2006;347(1):140-6.
2006: Sarah Holte; Ann J Melvin; James I Mullins; Nicole H Tobin; Lisa M Frenkel
Density-dependent decay in HIV-1 dynamics.
Journal of acquired immune deficiency syndromes (1999) 2006;41(3):266-76.
2006: Joshua T Herbeck; David C Nickle; Gerald Learn; Geoffrey S Gottlieb; Marcel E Curlin; Laura Heath; James I Mullins
Human immunodeficiency virus type 1 env evolves toward ancestral states upon transmission to a new host.
Journal of virology 2006;80(4):1637-44.
2006: Nicole Frahm; Photini Kiepiela; Sharon Adams; Caitlyn H Linde; Hannah S Hewitt; Kaori Sango; Margaret E Feeney; Marylyn M Addo; Mathias Lichterfeld; Matthew P Lahaie; Eunice Pae; Alysse Wurcel; Timothy Roach; M Anne St John; Marcus Altfeld; Francesco M Marincola; Corey Moore; Simon Mallal; Mary Carrington; David Heckerman; Todd M Allen; James I Mullins; Bette T Korber; Philip J R Goulder; Bruce D Walker; Christian Brander
Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.
Nature immunology 2006;7(2):173-8.
2006: James I Mullins; Mark A Jensen
Evolutionary dynamics of HIV-1 and the control of AIDS.
Current topics in microbiology and immunology 2006;299():171-92.
2005: Tae-Wook Chun; David C Nickle; J Shawn Justement; Danielle Large; Alice Semerjian; Marcel E Curlin; M Angeline O'Shea; Claire W Hallahan; Marybeth Daucher; Douglas J Ward; Susan Moir; James I Mullins; Colin Kovacs; Anthony Fauci
HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir.
The Journal of clinical investigation 2005;115(11):3250-5.
2005: Nicole A Doria-Rose; Gerald Learn; Allen Rodrigo; David C Nickle; F Li; Madhumita Mahalanabis; Michael T Hensel; S McLaughlin; Paul Edmonson; David Montefiori; Susan W Barnett; Nancy Haigwood; James I Mullins
Human immunodeficiency virus type 1 subtype B ancestral envelope protein is functional and elicits neutralizing antibodies in rabbits similar to those elicited by a circulating subtype B envelope.
Journal of virology 2005;79(17):11214-24.
2005: Angélique B van 't Wout; J Victor Swain; Michael Schindler; Ushnal Rao; Melissa S Pathmajeyan; James I Mullins; Frank Kirchhoff
Nef induces multiple genes involved in cholesterol synthesis and uptake in human immunodeficiency virus type 1-infected T cells.
Journal of virology 2005;79(15):10053-8.
2005: Nicole H Tobin; Gerald Learn; Sarah Holte; Yang Wang; Ann J Melvin; Jennifer L McKernan; Diane M Pawluk; Kathleen M Mohan; Paul F Lewis; James I Mullins; Lisa M Frenkel
Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: expression of archival virus and replication of virus.
Journal of virology 2005;79(15):9625-34.
2005: Ryan M Troyer; Kalonji R Collins; Awet Abraha; Erika Fraundorf; Dawn M Moore; Randall W Krizan; Zahra Toossi; Robert Colebunders; Mark A Jensen; James I Mullins; Guido Vanham; Eric J Arts
Changes in human immunodeficiency virus type 1 fitness and genetic diversity during disease progression.
Journal of virology 2005;79(14):9006-18.
2004: Yi Liu; David C Nickle; Daniel Shriner; Mark A Jensen; Gerald Learn; John E Mittler; James I Mullins
Molecular clock-like evolution of human immunodeficiency virus type 1.
Virology 2004;329(1):101-8.
2004: Marcel E Curlin; Geoffrey S Gottlieb; Stephen E Hawes; Papa Salif Sow; Ibrahima Ndoye; Cathy W Critchlow; Nancy B Kiviat; James I Mullins
No evidence for recombination between HIV type 1 and HIV type 2 within the envelope region in dually seropositive individuals from Senegal.
AIDS research and human retroviruses 2004;20(9):958-63.
2004: Daniel Shriner; Allen Rodrigo; David C Nickle; James I Mullins
Pervasive genomic recombination of HIV-1 in vivo.
Genetics 2004;167(4):1573-83.
2004: James I Mullins; David C Nickle; Laura Heath; Allen Rodrigo; Gerald Learn
Immunogen sequence: the fourth tier of AIDS vaccine design.
Expert review of vaccines 2004;3(4 Suppl):S151-9.
2004: Jennifer A Fulcher; Yon Hwangbo; Rafael Zioni; David C Nickle; Xudong Lin; Laura Heath; James I Mullins; Lawrence Corey; Tuofu Zhu
Compartmentalization of human immunodeficiency virus type 1 between blood monocytes and CD4+ T cells during infection.
Journal of virology 2004;78(15):7883-93.
2004: Tuofu Zhu; Shiu-Lok Hu; Feng Feng; Patricia Polacino; Huanliang Liu; Yon Hwangbo; Gerald Learn; James I Mullins; Lawrence Corey
Persistence of low levels of simian immunodeficiency virus in macaques that were transiently viremic by conventional testing.
Virology 2004;323(2):208-19.
2004: Xu G Yu; Marylyn M Addo; Beth A Perkins; Feili Wej; Almas Rathod; Shaun C Geer; Mark Parta; Daniel Cohen; David R Stone; Christopher J Russell; Giancarlo O Tanzi; Shan Mei; Alysse Wurcel; Nicole Frahm; Mathias Lichterfeld; Laura Heath; James I Mullins; Francesco M Marincola; Philip J R Goulder; Christian Brander; Todd Allen; Yunzhen Cao; Bruce D Walker; Marcus Altfeld
Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians.
AIDS research and human retroviruses 2004;20(5):557-64.
2004: Daniel Shriner; Raj Shankarappa; Mark A Jensen; David C Nickle; John E Mittler; Joseph B Margolick; James I Mullins
Influence of random genetic drift on human immunodeficiency virus type 1 env evolution during chronic infection.
Genetics 2004;166(3):1155-64.
2004: Geoffrey S Gottlieb; David C Nickle; Mark A Jensen; Kim G Wong; Jandre Grobler; Fusheng Li; Shan-Lu Liu; Cecilia Rademeyer; Gerald Learn; Salim S Abdool Karim; Carolyn Williamson; Lawrence Corey; Joseph B Margolick; James I Mullins
Dual HIV-1 infection associated with rapid disease progression.
Lancet 2004;363(9409):619-22.
2003: Mark A Jensen; Fu-Sheng Li; Angélique B van 't Wout; David C Nickle; Daniel Shriner; Hong-Xia He; Sherry McLaughlin; Raj Shankarappa; Joseph B Margolick; James I Mullins
Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences.
Journal of virology 2003;77(24):13376-88.
2003: David C Nickle; Daniel Shriner; John E Mittler; Lisa M Frenkel; James I Mullins
Importance and detection of virus reservoirs and compartments of HIV infection.
Current opinion in microbiology 2003;6(4):410-6.
2003: Geoffrey S Gottlieb; Papa Salif Sow; Stephen E Hawes; Ibrahima Ndoye; Awa M Coll-Seck; Marcel E Curlin; Cathy W Critchlow; Nancy B Kiviat; James I Mullins
Molecular epidemiology of dual HIV-1/HIV-2 seropositive adults from Senegal, West Africa.
AIDS research and human retroviruses 2003;19(7):575-84.
2003: Marcus Altfeld; Marylyn M Addo; Raj Shankarappa; Paul K Lee; Todd M Allen; Xu G Yu; Almas Rathod; Jason Harlow; Kristin M O'Sullivan; Mary N Johnston; Philip J R Goulder; James I Mullins; Eric S Rosenberg; Christian Brander; Bette Korber; Bruce D Walker
Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences.
Journal of virology 2003;77(13):7330-40.
2003: Jon P Anderson; Gerald Learn; Allen Rodrigo; Xi He; Yang Wang; Hillard Weinstock; Marcia L Kalish; Kenneth E Robbins; Leroy Hood; James I Mullins
Predicting demographic group structures based on DNA sequence data.
Molecular biology and evolution 2003;20(7):1168-80.
2003: Tuofu Zhu; Lawrence Corey; Yon Hwangbo; Jean M Lee; Gerald Learn; James I Mullins; M Juliana McElrath
Persistence of extraordinarily low levels of genetically homogeneous human immunodeficiency virus type 1 in exposed seronegative individuals.
Journal of virology 2003;77(11):6108-16.
2003: Lisa M Frenkel; Yang Wang; Gerald Learn; Jennifer L McKernan; Giovanina M Ellis; Kathleen M Mohan; Sarah Holte; Shannon M De Vange; Diane M Pawluk; Ann J Melvin; Paul F Lewis; Laura Heath; Ingrid A Beck; Madhumita Mahalanabis; Willscott E (Scott) Naugler; Nicole H Tobin; James I Mullins
Multiple viral genetic analyses detect low-level human immunodeficiency virus type 1 replication during effective highly active antiretroviral therapy.
Journal of virology 2003;77(10):5721-30.
2003: David C Nickle; Mark A Jensen; Daniel Shriner; Scott J Brodie; Lisa M Frenkel; John E Mittler; James I Mullins
Evolutionary indicators of human immunodeficiency virus type 1 reservoirs and compartments.
Journal of virology 2003;77(9):5540-6.
2003: Daniel Shriner; David C Nickle; Mark A Jensen; James I Mullins
Potential impact of recombination on sitewise approaches for detecting positive natural selection.
Genetical research 2003;81(2):115-21.
2003: David C Nickle; Mark A Jensen; Geoffrey S Gottlieb; Daniel Shriner; Gerald Learn; Allen Rodrigo; James I Mullins
Consensus and ancestral state HIV vaccines.
Science (New York, N.Y.) 2003;299(5612):1515-8; author reply 1515-8.
2003: Mark Dybul; Marybeth Daucher; Mark A Jensen; Claire W Hallahan; Tae-Wook Chun; Michael Belson; Bertha Hidalgo; David C Nickle; Christian Yoder; Julia A Metcalf; Richard Davey; Linda Ehler; Diane Kress-Rock; Elizabeth Nies-Kraske; Shuying Liu; James I Mullins; Anthony Fauci
Genetic characterization of rebounding human immunodeficiency virus type 1 in plasma during multiple interruptions of highly active antiretroviral therapy.
Journal of virology 2003;77(5):3229-37.
2003: Angélique B van 't Wout; Ginger K Lehrman; Svetlana A Mikheeva; Gemma C O'Keeffe; Michael G Katze; Roger Bumgarner; Gary K Geiss; James I Mullins
Cellular gene expression upon human immunodeficiency virus type 1 infection of CD4(+)-T-cell lines.
Journal of virology 2003;77(2):1392-402.
2002: Gerald Learn; David Muthui; Scott J Brodie; Tuofu Zhu; Kurt Diem; James I Mullins; Lawrence Corey
Virus population homogenization following acute human immunodeficiency virus type 1 infection.
Journal of virology 2002;76(23):11953-9.
2002: Shan-Lu Liu; John E Mittler; David C Nickle; Thera M Mulvania; Daniel Shriner; Allen Rodrigo; Barry Kosloff; Xi He; Lawrence Corey; James I Mullins
Selection for human immunodeficiency virus type 1 recombinants in a patient with rapid progression to AIDS.
Journal of virology 2002;76(21):10674-84.
2002: Angela Malaspina; Susan Moir; David C Nickle; Eileen T Donoghue; Kisani M Ogwaro; Linda Ehler; Shuying Liu; Jo Ann M Mican; Mark Dybul; Tae-Wook Chun; James I Mullins; Anthony Fauci
Human immunodeficiency virus type 1 bound to B cells: relationship to virus replicating in CD4+ T cells and circulating in plasma.
Journal of virology 2002;76(17):8855-63.
2002: Geoffrey S Gottlieb; Papa Salif Sow; Stephen E Hawes; Ibrahima Ndoye; Mary Redman; Awa M Coll-Seck; Mame A Faye-Niang; Aissatou Diop; Jane Kuypers; Cathy W Critchlow; Richard Respess; James I Mullins; Nancy B Kiviat
Equal plasma viral loads predict a similar rate of CD4+ T cell decline in human immunodeficiency virus (HIV) type 1- and HIV-2-infected individuals from Senegal, West Africa.
The Journal of infectious diseases 2002;185(7):905-14.
2002: Fusheng Li; James I Mullins
Site-directed mutagenesis facilitated by DpnI selection on hemimethylated DNA.
Methods in molecular biology (Clifton, N.J.) 2002;182():19-27.
2002: Tuofu Zhu; David Muthui; Sarah Holte; David C Nickle; Feng Feng; Scott J Brodie; Yon Hwangbo; James I Mullins; Lawrence Corey
Evidence for human immunodeficiency virus type 1 replication in vivo in CD14(+) monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy.
Journal of virology 2002;76(2):707-16.
2002: David C Nickle; Gerald Learn; Matthew W Rain; James I Mullins; John E Mittler
Curiously modern DNA for a "250 million-year-old" bacterium.
Journal of molecular evolution 2002;54(1):134-7.
2001: Raj Shankarappa; Ramdas Chatterjee; Gerald Learn; Dhruba K Neogi; M Ding; Pratima Roy; A Ghosh; L Kingsley; L Harrison; James I Mullins; Phalguni Gupta
Human immunodeficiency virus type 1 env sequences from Calcutta in eastern India: identification of features that distinguish subtype C sequences in India from other subtype C sequences.
Journal of virology 2001;75(21):10479-87.
2001: Jon P Anderson; Allen Rodrigo; Gerald Learn; Yang Wang; Hillard Weinstock; Marcia L Kalish; Kenneth E Robbins; Leroy Hood; James I Mullins
Substitution model of sequence evolution for the human immunodeficiency virus type 1 subtype B gp120 gene over the C2-V5 region.
Journal of molecular evolution 2001;53(1):55-62.
2001: S C Frey; E A Hoover; James I Mullins
Feline immunodeficiency virus cell entry.
Journal of virology 2001;75(11):5433-40.
2001: Marcus Altfeld; Eric S Rosenberg; Raj Shankarappa; Joia S Mukherjee; Frederick Hecht; Robert L Eldridge; Marylyn M Addo; S H Poon; Mary N Phillips; Gregory Robbins; PE Sax; SL Boswell; James O Kahn; Christian Brander; Philip J R Goulder; J A Levy; James I Mullins; Bruce D Walker
Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection.
The Journal of experimental medicine 2001;193(2):169-80.
2000: Tae-Wook Chun; Richard Davey; M Ostrowski; J Shawn Justement; D Engel; James I Mullins; Anthony Fauci
Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy.
Nature medicine 2000;6(7):757-61.
2000: D A Upchurch; Raj Shankarappa; James I Mullins
Position and degree of mismatches and the mobility of DNA heteroduplexes.
Nucleic acids research 2000;28(12):E69.
2000: Gary K Geiss; Roger Bumgarner; M C An; Michael B Agy; Angélique B van 't Wout; E Hammersmark; Victoria S Carter; D Upchurch; James I Mullins; Michael G Katze
Large-scale monitoring of host cell gene expression during HIV-1 infection using cDNA microarrays.
Virology 2000;266(1):8-16.
2000: L A Loeb; James I Mullins
Lethal mutagenesis of HIV by mutagenic ribonucleoside analogs.
AIDS research and human retroviruses 2000;16(1):1-3.
1999: Raj Shankarappa; Joseph B Margolick; Stephen J Gange; Allen Rodrigo; D Upchurch; Homayoon Farzadegan; Phalguni Gupta; Charles Rinaldo; Gerald Learn; X He; Xiao-Li Huang; James I Mullins
Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection.
Journal of virology 1999;73(12):10489-502.
1999: Fusheng Li; S L Liu; James I Mullins
Site-directed mutagenesis using uracil-containing double-stranded DNA templates and DpnI digestion.
BioTechniques 1999;27(4):734-8.
1999: Thera M Mulvania; JB Lynch; Michael N Robertson; Philip D Greenberg; William R Morton; James I Mullins
Antigen-specific cytokine responses in vaccinated Macaca nemestrina.
Journal of medical primatology 1999;28(4-5):181-9.
1999: Ann J Melvin; Allen Rodrigo; Kathleen M Mohan; P A Lewis; LA Manns-Arcuino; Robert W Coombs; James I Mullins; Lisa M Frenkel
HIV-1 dynamics in children.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1999;20(5):468-73.
1999: Allen Rodrigo; E G Shpaer; E L Delwart; A K Iversen; M V Gallo; Jurgen Brojatsch; M S Hirsch; Bruce D Walker; James I Mullins
Coalescent estimates of HIV-1 generation time in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2187-91.
1999: Lawrence A Loeb; J M Essigmann; F Kazazi; Jianhua Zhang; K D Rose; James I Mullins
Lethal mutagenesis of HIV with mutagenic nucleoside analogs.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1492-7.
1998: Charles Rinaldo; Phalguni Gupta; Xiao-Li Huang; Zheng Fan; James I Mullins; Stephen J Gange; Homayoon Farzadegan; Raj Shankarappa; ALVARO MUNOZ; Joseph B Margolick
Anti-HIV type 1 memory cytotoxic T lymphocyte responses associated with changes in CD4+ T cell numbers in progression of HIV type 1 infection.
AIDS research and human retroviruses 1998;14(16):1423-33.
1998: Lisa M Frenkel; James I Mullins; Gerald Learn; LA Manns-Arcuino; B L Herring; Marcia L Kalish; R W Steketee; Donald M Thea; Joan Nichols; S L Liu; ABDALLAH HARMACHE; X He; David Muthui; A Madan; L Hood; Ashley T Haase; Mary Zupancic; KA Staskus; Steven Wolinsky; Paul Krogstad; J Zhao; I Chen; R Koup; D Ho; Bette Korber; Raymond Apple; Robert W Coombs; Savita Pahwa; Norbert J Roberts
Genetic evaluation of suspected cases of transient HIV-1 infection of infants.
Science (New York, N.Y.) 1998;280(5366):1073-7.
1998: Stephen Polyak; Susan McArdle; Shan-Lu Liu; Daniel G Sullivan; Minjun Chung; WT Hofgärtner; Robert L Carithers; Brian J McMahon; James I Mullins; Lawrence Corey; David R Gretch
Evolution of hepatitis C virus quasispecies in hypervariable region 1 and the putative interferon sensitivity-determining region during interferon therapy and natural infection.
Journal of virology 1998;72(5):4288-96.
1998: Thera M Mulvania; E Coon; Lewis H Kuller; Michael B Agy; William R Morton; James I Mullins
Natural history of SIVmac BK28 and H824 infection in Macaca nemestrina.
Journal of medical primatology 1998;27(2-3):87-93.
1998: Raj Shankarappa; Phalguni Gupta; Gerald Learn; Allen Rodrigo; Charles Rinaldo; Michael C Gorry; James I Mullins; P L Nara; Garth D Ehrlich
Evolution of human immunodeficiency virus type 1 envelope sequences in infected individuals with differing disease progression profiles.
Virology 1998;241(2):251-9.
1998: Paul Edmonson; Michael Murphey-Corb; Louis N Martin; C Delahunty; Jonathan Luke Heeney; H Kornfeld; P R Donahue; Gerald Learn; L Hood; James I Mullins
Evolution of a simian immunodeficiency virus pathogen.
Journal of virology 1998;72(1):405-14.
1997: Allen Rodrigo; P C Goracke; K Rowhanian; James I Mullins
Quantitation of target molecules from polymerase chain reaction-based limiting dilution assays.
AIDS research and human retroviruses 1997;13(9):737-42.
1997: Shan-Lu Liu; Timothy W Schacker; Luwy Musey; Daniel Shriner; M Juliana McElrath; Lawrence Corey; James I Mullins
Divergent patterns of progression to AIDS after infection from the same source: human immunodeficiency virus type 1 evolution and antiviral responses.
Journal of virology 1997;71(6):4284-95.
1996: Allen Rodrigo; James I Mullins
Human immunodeficiency virus type 1 molecular evolution and the measure of selection.
AIDS research and human retroviruses 1996;12(18):1681-5.
1996: C Goulston; E Stevens; D Gallo; James I Mullins; Carl Hanson; David Katzenstein
Human immunodeficiency virus in plasma and genital secretions during the menstrual cycle.
The Journal of infectious diseases 1996;174(4):858-61.
1996: Sandra L Quackenbush; Gregg A Dean; James I Mullins; Edward A Hoover
Analysis of FeLV-FAIDS provirus burden and productive infection in lymphocyte subsets in vivo.
Virology 1996;223(1):1-9.
1996: Gerald Learn; B T Korber; Brian Foley; B H Hahn; Steven Wolinsky; James I Mullins
Maintaining the integrity of human immunodeficiency virus sequence databases.
Journal of virology 1996;70(8):5720-30.
1996: S L Liu; Allen Rodrigo; Raj Shankarappa; Gerald Learn; L Hsu; Ori Davidov; Lue Ping Zhao; James I Mullins
HIV quasispecies and resampling.
Science (New York, N.Y.) 1996;273(5274):415-6.
1996: Sandra L Quackenbush; James I Mullins; Edward A Hoover
Replication kinetics and cell tropism of an immunosuppressive feline leukaemia virus.
The Journal of general virology 1996;77 ( Pt 7)():1411-20.
1996: M Juliana McElrath; Lawrence Corey; Philip D Greenberg; T J Matthews; David C Montefiori; Lee Rowen; Leroy Hood; James I Mullins
Human immunodeficiency virus type 1 infection despite prior immunization with a recombinant envelope vaccine regimen.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):3972-7.
1996: Edward A Hoover; James I Mullins; H J Chu; T L Wasmoen
Efficacy of an inactivated feline leukemia virus vaccine.
AIDS research and human retroviruses 1996;12(5):379-83.
1996: S P Mossman; Françoise Bex; P Berglund; J Arthos; S P O'Neil; D Riley; D H Maul; Claudine Bruck; P Momin; Arsène Burny; P N Fultz; James I Mullins; Peter Liljeström; Edward A Hoover
Protection against lethal simian immunodeficiency virus SIVsmmPBj14 disease by a recombinant Semliki Forest virus gp160 vaccine and by a gp120 subunit vaccine.
Journal of virology 1996;70(3):1953-60.
1996: A K Iversen; Robert W Shafer; K Wehrly; M A Winters; James I Mullins; B Chesebro; Thomas C Merigan
Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy.
Journal of virology 1996;70(2):1086-90.
1996: C M de Noronha; T A Reinhart; James I Mullins
Generation and role of defective proviruses in cytopathic feline leukemia virus (FeLV-FAIDS) infections.
Journal of virology 1996;70(1):359-67.
1995: B T Korber; Gerald Learn; James I Mullins; B H Hahn; S Wolinsky
Protecting HIV databases.
Nature 1995;378(6554):242-4.
1995: Edward A Hoover; James I Mullins; H J Chu; T L Wasmoen
Development and testing of an inactivated feline leukemia virus vaccine.
Seminars in veterinary medicine and surgery (small animal) 1995;10(4):238-43.
1995: Christopher H Contag; Pamela R Contag; James I Mullins; Stan Spilman; David K Stevenson; David A Benaron
Photonic detection of bacterial pathogens in living hosts.
Molecular microbiology 1995;18(4):593-603.
1995: A K Ghosh; James I Mullins
cDNA encoding a functional feline liver/bone/kidney-type alkaline phosphatase.
Archives of biochemistry and biophysics 1995;322(1):240-9.
1995: A K Iversen; E G Shpaer; Allen Rodrigo; M S Hirsch; Bruce D Walker; H W Sheppard; Thomas C Merigan; James I Mullins
Persistence of attenuated rev genes in a human immunodeficiency virus type 1-infected asymptomatic individual.
Journal of virology 1995;69(9):5743-53.
1995: D L Sodora; Justin Courcelle; Jurgen Brojatsch; A Berson; Y C Wang; S W Dow; Edward A Hoover; James I Mullins
Analysis of a feline immunodeficiency virus provirus reveals patterns of gene sequence conservation distinct from human immunodeficiency virus type 1.
AIDS research and human retroviruses 1995;11(4):531-3.
1995: Eric L Delwart; B Herring; Allen Rodrigo; James I Mullins
Genetic subtyping of human immunodeficiency virus using a heteroduplex mobility assay.
PCR methods and applications 1995;4(5):S202-16.
1995: Rongfu Wang; James I Mullins
Mammalian cell/vaccinia virus expression vectors with increased stability of retroviral sequences in Escherichia coli: production of feline immunodeficiency virus envelope protein.
Gene 1995;153(2):197-202.
1994: E G Shpaer; Eric L Delwart; C L Kuiken; J Goudsmit; M H Bachmann; James I Mullins
Conserved V3 loop sequences and transmission of human immunodeficiency virus type 1.
AIDS research and human retroviruses 1994;10(12):1679-84.
1994: Aleksei F Bobkov; R Cheingsong-Popov; M Garaev; A Rzhaninova; Pontiano Kaleebu; Simon Beddows; M H Bachmann; James I Mullins; joost louwagie; Wouter Janssens
Identification of an env G subtype and heterogeneity of HIV-1 strains in the Russian Federation and Belarus.
AIDS (London, England) 1994;8(12):1649-55.
1994: M H Bachmann; Eric L Delwart; E G Shpaer; P Lingenfelter; R Singal; James I Mullins
Rapid genetic characterization of HIV type 1 strains from four World Health Organization-sponsored vaccine evaluation sites using a heteroduplex mobility assay. WHO Network for HIV Isolation and Characterization.
AIDS research and human retroviruses 1994;10(11):1345-53.
1994: Eric L Delwart; H W Sheppard; Bruce D Walker; J Goudsmit; James I Mullins
Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays.
Journal of virology 1994;68(10):6672-83.
1994: joost louwagie; Eric L Delwart; James I Mullins; Francine E McCutchan; G Eddy; Donald S. Burke
Genetic analysis of HIV-1 isolates from Brazil reveals presence of two distinct genetic subtypes.
AIDS research and human retroviruses 1994;10(5):561-7.
1994: D L Sodora; E G Shpaer; B E Kitchell; S W Dow; Edward A Hoover; James I Mullins
Identification of three feline immunodeficiency virus (FIV) env gene subtypes and comparison of the FIV and human immunodeficiency virus type 1 evolutionary patterns.
Journal of virology 1994;68(4):2230-8.
1994: Manuel Grez; Ursula Dietrich; P Balfe; Hagen von Briesen; J K Maniar; G Mahambre; Eric L Delwart; James I Mullins; Helga Rübsamen-Waigmann
Genetic analysis of human immunodeficiency virus type 1 and 2 (HIV-1 and HIV-2) mixed infections in India reveals a recent spread of HIV-1 and HIV-2 from a single ancestor for each of these viruses.
Journal of virology 1994;68(4):2161-8.
1993: Eric L Delwart; E G Shpaer; joost louwagie; Francine E McCutchan; Manuel Grez; Helga Rübsamen-Waigmann; James I Mullins
Genetic relationships determined by a DNA heteroduplex mobility assay: analysis of HIV-1 env genes.
Science (New York, N.Y.) 1993;262(5137):1257-61.
1993: Todd A Reinhart; A K Ghosh; Edward A Hoover; James I Mullins
Distinct superinfection interference properties yet similar receptor utilization by cytopathic and noncytopathic feline leukemia viruses.
Journal of virology 1993;67(9):5153-62.
1993: E G Shpaer; James I Mullins
Rates of amino acid change in the envelope protein correlate with pathogenicity of primate lentiviruses.
Journal of molecular evolution 1993;37(1):57-65.
1993: Bruce Kristal; Todd A Reinhart; Edward A Hoover; James I Mullins
Interference with superinfection and with cell killing and determination of host range and growth kinetics mediated by feline leukemia virus surface glycoproteins.
Journal of virology 1993;67(7):4142-53.
1993: Z R Israel; Gregg A Dean; D H Maul; S P O'Neil; M J Dreitz; James I Mullins; P N Fultz; Edward A Hoover
Early pathogenesis of disease caused by SIVsmmPBj14 molecular clone 1.9 in macaques.
AIDS research and human retroviruses 1993;9(3):277-86.
1992: C M de Noronha; James I Mullins
Amplimers with 3'-terminal phosphorothioate linkages resist degradation by vent polymerase and reduce Taq polymerase mispriming.
PCR methods and applications 1992;2(2):131-6.
1992: Jurgen Brojatsch; Bruce Kristal; G A Viglianti; R Khiroya; Edward A Hoover; James I Mullins
Feline leukemia virus subgroup C phenotype evolves through distinct alterations near the N terminus of the envelope surface glycoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(18):8457-61.
1992: Gregg A Dean; P M Groshek; James I Mullins; Edward A Hoover
Hematopoietic target cells of anemogenic subgroup C versus nonanemogenic subgroup A feline leukemia virus.
Journal of virology 1992;66(9):5561-8.
1992: Stephen Dewhurst; J E Embretson; P N Fultz; James I Mullins
Molecular clones from a non-acutely pathogenic derivative of SIVsmmPBj14: characterization and comparison to acutely pathogenic clones.
AIDS research and human retroviruses 1992;8(6):1179-87.
1992: Julie Overbaugh; Edward A Hoover; James I Mullins; D P Burns; L Rudensey; Sandra L Quackenbush; V Stallard; P R Donahue
Structure and pathogenicity of individual variants within an immunodeficiency disease-inducing isolate of FeLV.
Virology 1992;188(2):558-69.
1992: A K Ghosh; M H Bachmann; Edward A Hoover; James I Mullins
Identification of a putative receptor for subgroup A feline leukemia virus on feline T cells.
Journal of virology 1992;66(6):3707-14.
1991: Edward A Hoover; N A Perigo; Sandra L Quackenbush; C K Mathiason-DuBard; Julie Overbaugh; W S Kloetzer; J H Elder; James I Mullins
Protection against feline leukemia virus infection by use of an inactivated virus vaccine.
Journal of the American Veterinary Medical Association 1991;199(10):1392-401.
1991: Edward A Hoover; James I Mullins
Feline leukemia virus infection and diseases.
Journal of the American Veterinary Medical Association 1991;199(10):1287-97.
1991: P R Donahue; Sandra L Quackenbush; M V Gallo; C M deNoronha; Julie Overbaugh; Edward A Hoover; James I Mullins
Viral genetic determinants of T-cell killing and immunodeficiency disease induction by the feline leukemia virus FeLV-FAIDS.
Journal of virology 1991;65(8):4461-9.
1991: Edward A Hoover; J P Ebner; N S Zeidner; James I Mullins
Early therapy of feline leukemia virus infection (FeLV-FAIDS) with 9-(2-phosphonylmethoxyethyl)adenine (PMEA).
Antiviral research 1991;16(1):77-92.
1991: D Pardi; Edward A Hoover; Sandra L Quackenbush; James I Mullins; G N Callahan
Selective impairment of humoral immunity in feline leukemia virus-induced immunodeficiency.
Veterinary immunology and immunopathology 1991;28(3-4):183-200.
1991: James I Mullins; Edward A Hoover; Sandra L Quackenbush; P R Donahue
Disease progression and viral genome variants in experimental feline leukemia virus-induced immunodeficiency syndrome.
Journal of acquired immune deficiency syndromes 1991;4(6):547-57.
1990: Sandra L Quackenbush; P R Donahue; Gregg A Dean; Matthew Myles; C D Ackley; Max D Cooper; James I Mullins; Edward A Hoover
Lymphocyte subset alterations and viral determinants of immunodeficiency disease induction by the feline leukemia virus FeLV-FAIDS.
Journal of virology 1990;64(11):5465-74.
1990: E G Shpaer; James I Mullins
Selection against CpG dinucleotides in lentiviral genes: a possible role of methylation in regulation of viral expression.
Nucleic acids research 1990;18(19):5793-7.
1990: G A Viglianti; P L Sharma; James I Mullins
Simian immunodeficiency virus displays complex patterns of RNA splicing.
Journal of virology 1990;64(9):4207-16.
1990: N S Zeidner; Matthew Myles; C K Mathiason-DuBard; M J Dreitz; James I Mullins; Edward A Hoover
Alpha interferon (2b) in combination with zidovudine for the treatment of presymptomatic feline leukemia virus-induced immunodeficiency syndrome.
Antimicrobial agents and chemotherapy 1990;34(9):1749-56.
1990: Mary Poss; Sandra L Quackenbush; James I Mullins; Edward A Hoover
Characterization and significance of delayed processing of the feline leukemia virus FeLV-FAIDS envelope glycoprotein.
Journal of virology 1990;64(9):4338-45.
1990: Stephen Dewhurst; J E Embretson; D C Anderson; James I Mullins; P N Fultz
Sequence analysis and acute pathogenicity of molecularly cloned SIVSMM-PBj14.
Nature 1990;345(6276):636-40.
1990: James I Mullins; Edward A Hoover; P R Donahue; Stephen Dewhurst; Sandra L Quackenbush; Michael Murphey-Corb; Louis N Martin; P N Fultz; M V Gallo; Todd A Reinhart
The FeLV and SIV AIDS pathogenesis models: search for and analysis of molecularly defined pathogens.
Developments in biological standardization 1990;72():167-71.
1990: Edward A Hoover; Sandra L Quackenbush; Mary Poss; R E Dornsife; Julie Overbaugh; P R Donahue; N O Riedel; G A Vigilanti; R Khiroya; James I Mullins
Pathogenic mechanisms of immunodeficiency syndrome and aplastic anemia induced by feline leukemia viruses.
Developments in biological standardization 1990;72():163-6.
1990: N S Zeidner; L M Rose; C K Mathiason-DuBard; Matthew Myles; D L Hill; James I Mullins; Edward A Hoover
Zidovudine in combination with alpha interferon and interleukin-2 as prophylactic therapy for FeLV-induced immunodeficiency syndrome (FeLV-FAIDS).
Journal of acquired immune deficiency syndromes 1990;3(8):787-96.
1990: Edward A Hoover; N S Zeidner; James I Mullins
Therapy of presymptomatic FeLV-induced immunodeficiency syndrome with AZT in combination with alpha interferon.
Annals of the New York Academy of Sciences 1990;616():258-69.
1989: James I Mullins; Edward A Hoover; Julie Overbaugh; Sandra L Quackenbush; P R Donahue; Mary Poss
FeLV-FAIDS-induced immunodeficiency syndrome in cats.
Veterinary immunology and immunopathology 1989;21(1):25-37.
1989: D L Doggett; A L Drake; V Hirsch; M E Rowe; V Stallard; James I Mullins
Structure, origin, and transforming activity of feline leukemia virus-myc recombinant provirus FTT.
Journal of virology 1989;63(5):2108-17.
1989: N S Zeidner; J D Strobel; N A Perigo; D L Hill; James I Mullins; Edward A Hoover
Treatment of FeLV-induced immunodeficiency syndrome (FeLV-FAIDS) with controlled release capsular implantation of 2',3'-dideoxycytidine.
Antiviral research 1989;11(3):147-60.
1989: Sandra L Quackenbush; James I Mullins; Edward A Hoover
Colony forming T lymphocyte deficit in the development of feline retrovirus induced immunodeficiency syndrome.
Blood 1989;73(2):509-16.
1989: R E Dornsife; P W Gasper; James I Mullins; Edward A Hoover
In vitro erythrocytopathic activity of an aplastic anemia-inducing feline retrovirus.
Experimental hematology 1989;17(2):138-44.
1989: R E Dornsife; P W Gasper; James I Mullins; Edward A Hoover
Induction of aplastic anemia by intra-bone marrow inoculation of a molecularly cloned feline retrovirus.
Leukemia research 1989;13(9):745-55.
1989: Edward A Hoover; N S Zeidner; N A Perigo; Sandra L Quackenbush; J D Strobel; D L Hill; James I Mullins
Feline leukemia virus-induced immunodeficiency syndrome in cats as a model for evaluation of antiretroviral therapy.
Intervirology 1989;30 Suppl 1():12-25.
1989: Mary Poss; James I Mullins; Edward A Hoover
Posttranslational modifications distinguish the envelope glycoprotein of the immunodeficiency disease-inducing feline leukemia virus retrovirus.
Journal of virology 1989;63(1):189-95.
1988: G A Viglianti; James I Mullins
Functional comparison of transactivation by simian immunodeficiency virus from rhesus macaques and human immunodeficiency virus type 1.
Journal of virology 1988;62(12):4523-32.
1988: Julie Overbaugh; N Riedel; Edward A Hoover; James I Mullins
Transduction of endogenous envelope genes by feline leukaemia virus in vitro.
Nature 1988;332(6166):731-4.
1988: N Riedel; Edward A Hoover; R E Dornsife; James I Mullins
Pathogenic and host range determinants of the feline aplastic anemia retrovirus.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2758-62.
1988: P R Donahue; Edward A Hoover; G A Beltz; N Riedel; V M Hirsch; Julie Overbaugh; James I Mullins
Strong sequence conservation among horizontally transmissible, minimally pathogenic feline leukemia viruses.
Journal of virology 1988;62(3):722-31.
1988: Julie Overbaugh; P R Donahue; Sandra L Quackenbush; Edward A Hoover; James I Mullins
Molecular cloning of a feline leukemia virus that induces fatal immunodeficiency disease in cats.
Science (New York, N.Y.) 1988;239(4842):906-10.
1987: Klaus Strebhardt; James I Mullins; C Bruck; Helga Rübsamen-Waigmann
Additional member of the protein-tyrosine kinase family: the src- and lck-related protooncogene c-tkl.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):8778-82.
1987: Edward A Hoover; James I Mullins; Sandra L Quackenbush; P W Gasper
Experimental transmission and pathogenesis of immunodeficiency syndrome in cats.
Blood 1987;70(6):1880-92.