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Gerald Münch

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Tanja Sauer; Martin Raithel; Jürgen Kressel; Gerald Münch; Monika Pischetsrieder
Activation of the transcription factor Nrf2 in macrophages, Caco-2 cells and intact human gut tissue by Maillard reaction products and coffee.
Megan L Steele; Nikolaus J Sucher; John Truong; Suresh Govindaraghavan; Lezanne Ooi; Gerald Münch
Cytoprotective properties of traditional Chinese medicinal herbal extracts in hydrogen peroxide challenged human U373 astroglia cells.
Megan L Steele; Lezanne Ooi; Stacey Fuller; Cindy Kersaitis; Annette E Maczurek; Gerald Münch
Chronic inflammation alters production and release of glutathione and related thiols in human U373 astroglial cells.

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2013: Tanja Sauer; Martin Raithel; Jürgen Kressel; Gerald Münch; Monika Pischetsrieder
Activation of the transcription factor Nrf2 in macrophages, Caco-2 cells and intact human gut tissue by Maillard reaction products and coffee.
Amino acids 2013;44(6):1427-39.
2013: Megan L Steele; Nikolaus J Sucher; John Truong; Suresh Govindaraghavan; Lezanne Ooi; Gerald Münch
Cytoprotective properties of traditional Chinese medicinal herbal extracts in hydrogen peroxide challenged human U373 astroglia cells.
Neurochemistry international 2013;62(5):522-9.
2013: Megan L Steele; Lezanne Ooi; Stacey Fuller; Cindy Kersaitis; Annette E Maczurek; Gerald Münch
Chronic inflammation alters production and release of glutathione and related thiols in human U373 astroglial cells.
Cellular and molecular neurobiology 2013;33(1):19-30.
2013: Lezanne Ooi; Anne Poljak; Perminder Sachdev; Kuldip Sidhu; Greg Sutherland; Michael D O'Connor; Gerald Münch
Induced pluripotent stem cells as tools for disease modelling and drug discovery in Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2013;120(1):103-11.
2012: Megan L Steele; Lezanne Ooi; Gerald Münch
Development of a high-performance liquid chromatography method for the simultaneous quantitation of glutathione and related thiols.
Analytical biochemistry 2012;429(1):45-52.
2012: Rebekka Wild; Lezanne Ooi; Velandai Srikanth; Gerald Münch
A quick, convenient and economical method for the reliable determination of methylglyoxal in millimolar concentrations: the N-acetyl-L-cysteine assay.
Analytical and bioanalytical chemistry 2012;403(9):2577-81.
2011: Tanja Sauer; Martin Raithel; Jürgen Kressel; Gerald Münch; Sonja Muscat; Monika Pischetsrieder
Nuclear translocation of NF-κB in intact human gut tissue upon stimulation with coffee and roasting products.
Food & function 2011;2(9):529-40.
2011: Velandai Srikanth; Annette Maczurek; Thanh Phan; Megan Steele; Bernadette Westcott; Damian Juskiw; Gerald Münch
Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease.
Neurobiology of aging 2011;32(5):763-77.
2011: Anton Rahmadi; Nicole Steiner; Gerald Münch
Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2011;49(3):385-91.
2010: Martina Krautwald; Gerald Münch
Advanced glycation end products as biomarkers and gerontotoxins - A basis to explore methylglyoxal-lowering agents for Alzheimer's disease?
Experimental gerontology 2010;45(10):744-51.
2010: Stacey Fuller; Megan Steele; Gerald Münch
Activated astroglia during chronic inflammation in Alzheimer's disease--do they neglect their neurosupportive roles?
Mutation research 2010;690(1-2):40-9.
2010: Dave Chandler; Ameha Woldu; Anton Rahmadi; Kirubakaran Shanmugam; Nicole Steiner; Elise Wright; Obdulio Benavente-García; Oliver Schulz; Julián Castillo; Gerald Münch
Effects of plant-derived polyphenols on TNF-alpha and nitric oxide production induced by advanced glycation endproducts.
Molecular nutrition & food research 2010;54 Suppl 2():S141-50.
2010: Grant Stuchbury; Gerald Münch
Optimizing the generation of stable neuronal cell lines via pre-transfection restriction enzyme digestion of plasmid DNA.
Cytotechnology 2010;62(3):189-94.
2010: Elizabeth Hansen; Martina Krautwald; Annette E Maczurek; Grant Stuchbury; Phillip Fromm; Megan Steele; Oliver Schulz; Obdulio Benavente Garcia; Julian Castillo; Heinrich Korner; Gerald Münch
A versatile high throughput screening system for the simultaneous identification of anti-inflammatory and neuroprotective compounds.
Journal of Alzheimer's disease : JAD 2010;19(2):451-64.
2009: Stacey Fuller; Gerald Münch; Megan Steele
Activated astrocytes: a therapeutic target in Alzheimer's disease?
Expert review of neurotherapeutics 2009;9(11):1585-94.
2009: Sonja Muscat; Monika Pischetsrieder; Annette Maczurek; Sven Rothemund; Gerald Münch
Cytotoxicity of Maillard reaction products determined with a peptide spot library.
Molecular nutrition & food research 2009;53(8):1019-29.
2009: Jörg Hegele; Gerald Münch; Monika Pischetsrieder
Identification of hydrogen peroxide as a major cytotoxic component in Maillard reaction mixtures and coffee.
Molecular nutrition & food research 2009;53(6):760-9.
2008: Katrin Bigl; Frank Gaunitz; Annett Schmitt; Sven Rothemund; Reinhard Schliebs; Gerald Münch; Thomas Arendt
Cytotoxicity of advanced glycation endproducts in human micro- and astroglial cell lines depends on the degree of protein glycation.
Journal of neural transmission (Vienna, Austria : 1996) 2008;115(11):1545-56.
2008: Annette Maczurek; Klaus Hager; Marlene Kenklies; Matt Sharman; Ralph Martins; Jürgen Engel; David Carlson; Gerald Münch
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease.
Advanced drug delivery reviews 2008;60(13-14):1463-70.
2008: Annette Maczurek; Kirubakaran Shanmugam; Gerald Münch
Inflammation and the redox-sensitive AGE-RAGE pathway as a therapeutic target in Alzheimer's disease.
Annals of the New York Academy of Sciences 2008;1126():147-51.
2008: Kirubakaran Shanmugam; Lina Holmquist; Megan Steele; Grant Stuchbury; Katrin Berbaum; Oliver Schulz; Obdulio Benavente-García; Julián Castillo; James Burnell; Vernon Garcia Rivas; Geoff Dobson; Gerald Münch
Plant-derived polyphenols attenuate lipopolysaccharide-induced nitric oxide and tumour necrosis factor production in murine microglia and macrophages.
Molecular nutrition & food research 2008;52(4):427-38.
2008: Katrin Berbaum; Kirubakaran Shanmugam; Grant Stuchbury; Florian Wiede; Heinrich Korner; Gerald Münch
Induction of novel cytokines and chemokines by advanced glycation endproducts determined with a cytometric bead array.
Cytokine 2008;41(3):198-203.
2007: Katrin Bigl; Annett Schmitt; Ina Meiners; Gerald Münch; Thomas Arendt
Comparison of results of the CellTiter Blue, the tetrazolium (3-[4,5-dimethylthioazol-2-yl]-2,5-diphenyl tetrazolium bromide), and the lactate dehydrogenase assay applied in brain cells after exposure to advanced glycation endproducts.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(5):962-71.
2007: Susana Garcia de Arriba; Grant Stuchbury; Jennifer Yarin; James Burnell; Claudia Loske; Gerald Münch
Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers.
Neurobiology of aging 2007;28(7):1044-50.
2007: Sonja Muscat; Joana Pelka; Jörg Hegele; Bernd Weigle; Gerald Münch; Monika Pischetsrieder
Coffee and Maillard products activate NF-kappaB in macrophages via H2O2 production.
Molecular nutrition & food research 2007;51(5):525-35.
2007: Björn Kuhla; Cathleen Haase; Katharina Flach; Hans-Joachim Lüth; Thomas Arendt; Gerald Münch
Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on tau aggregation and filament formation.
The Journal of biological chemistry 2007;282(10):6984-91.
2007: K Hager; M Kenklies; J McAfoose; J Engel; Gerald Münch
Alpha-lipoic acid as a new treatment option for Alzheimer's disease--a 48 months follow-up analysis.
Journal of neural transmission. Supplementum 2007;(72):189-93.
2007: L Holmquist; Grant Stuchbury; M Steele; Gerald Münch
Hydrogen peroxide is a true first messenger.
Journal of neural transmission. Supplementum 2007;(72):39-41.
2007: Angela Schmidt; Björn Kuhla; Katrin Bigl; Gerald Münch; Thomas Arendt
Cell cycle related signaling in Neuro2a cells proceeds via the receptor for advanced glycation end products.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(11):1413-24.
2007: Lina Holmquist; Grant Stuchbury; Katrin Berbaum; Sonja Muscat; Simon Young; Klaus Hager; Jürgen Engel; Gerald Münch
Lipoic acid as a novel treatment for Alzheimer's disease and related dementias.
Pharmacology & therapeutics 2007;113(1):154-64.
2007: Megan Steele; Grant Stuchbury; Gerald Münch
The molecular basis of the prevention of Alzheimer's disease through healthy nutrition.
Experimental gerontology 2007;42(1-2):28-36.
2007: Björn Kuhla; Katharina Boeck; Angela Schmidt; Vera Ogunlade; Thomas Arendt; Gerald Münch; Hans-Joachim Lüth
Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains.
Neurobiology of aging 2007;28(1):29-41.
2006: André K Langer; H Fai Poon; Gerald Münch; Bert C Lynn; Thomas Arendt; D Allan Butterfield
Identification of AGE-modified proteins in SH-SY5Y and OLN-93 cells.
Neurotoxicity research 2006;9(4):255-68.
2006: Björn Kuhla; Hans-Joachim Lüth; Dietrich Haferburg; Michael Weick; Andreas Reichenbach; Thomas Arendt; Gerald Münch
Pathological effects of glyoxalase I inhibition in SH-SY5Y neuroblastoma cells.
Journal of neuroscience research 2006;83(8):1591-600.
2006: Björn Kuhla; Katharina Boeck; Hans-Joachim Lüth; Angela Schmidt; Bernd Weigle; Marc Schmitz; Vera Ogunlade; Gerald Münch; Thomas Arendt
Age-dependent changes of glyoxalase I expression in human brain.
Neurobiology of aging 2006;27(6):815-22.
2006: Susana Garcia de Arriba; Ute Krügel; Ralf Regenthal; Zacharie Vissiennon; Ester Verdaguer; Anne Lewerenz; Elvira García-Jordá; Mercè Pallas; Antoni Camins; Gerald Münch; Karen Nieber; Clemens Allgaier
Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity.
Free radical biology & medicine 2006;40(5):779-90.
2006: Anke Huber; Grant Stuchbury; Alexander Bürkle; James Burnell; Gerald Münch
Neuroprotective therapies for Alzheimer's disease.
Current pharmaceutical design 2006;12(6):705-17.
2005: Annett Schmitt; Ina Meiners; Johannes Schmitt; Joachim Nöller; Christian Ihling; Gerald Münch; Andrea Sinz; Karen Nieber
Two analytical methods to study the interaction of AGEs with cell surface proteins.
Journal of biochemical and biophysical methods 2005;65(2-3):121-36.
2005: Julie Webster; M Wilke; Peter Stahl; Rosemarie Kientsch-Engel; Gerald Münch
[Maillard reaction products in food as pro-inflammatory and pro-arteriosclerotic factors of degenerative diseases].
Zeitschrift für Gerontologie und Geriatrie 2005;38(5):347-53.
2005: C Wihler; S Schäfer; K Schmid; Elizabeth K Deemer; Gerald Münch; M Bleich; Andreas E Busch; T Dingermann; Veronika Somoza; John W Baynes; Jochen Huber
Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition.
Diabetologia 2005;48(8):1645-53.
2005: Gerald Münch; Katrin Berbaum; Christin Urban; Reinhard Schinzel
Proteins of Thermus thermophilus are resistant to glycation-induced protein precipitation: an evolutionary adaptation to life at extreme temperatures?
Annals of the New York Academy of Sciences 2005;1043():865-75.
2005: Björn Kuhla; Hans-Joachim Lüth; Dietrich Haferburg; Katharina Boeck; Thomas Arendt; Gerald Münch
Methylglyoxal, glyoxal, and their detoxification in Alzheimer's disease.
Annals of the New York Academy of Sciences 2005;1043():211-6.
2005: Torsten Richter; Gerald Münch; Hans-Joachim Lüth; Thomas Arendt; Rosemarie Kientsch-Engel; Peter Stahl; Dörte Fengler; Björn Kuhla
Immunochemical crossreactivity of antibodies specific for "advanced glycation endproducts" with "advanced lipoxidation endproducts".
Neurobiology of aging 2005;26(4):465-74.
2005: Annett Schmitt; Johannes Schmitt; Gerald Münch; Jovana Gasic-Milencovic
Characterization of advanced glycation end products for biochemical studies: side chain modifications and fluorescence characteristics.
Analytical biochemistry 2005;338(2):201-15.
2005: Grant Stuchbury; Gerald Münch
Alzheimer's associated inflammation, potential drug targets and future therapies.
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(3):429-53.
2005: Hans-Joachim Lüth; Vera Ogunlade; Björn Kuhla; Rosemarie Kientsch-Engel; Peter Stahl; Julie Webster; Thomas Arendt; Gerald Münch
Age- and stage-dependent accumulation of advanced glycation end products in intracellular deposits in normal and Alzheimer's disease brains.
Cerebral cortex (New York, N.Y. : 1991) 2005;15(2):211-20.
2005: Naila Ahmed; Usman Ahmed; Paul J Thornalley; Klaus Hager; Gerd Fleischer; Gerald Münch
Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment.
Journal of neurochemistry 2005;92(2):255-63.
2005: Julie Webster; Christin Urban; Katrin Berbaum; Claudia Loske; Alán Alpár; Ulrich Gärtner; Susana Garcia de Arriba; Thomas Arendt; Gerald Münch
The carbonyl scavengers aminoguanidine and tenilsetam protect against the neurotoxic effects of methylglyoxal.
Neurotoxicity research 2005;7(1-2):95-101.
2004: Feng Chen; M Axel Wollmer; Frederic Hoerndli; Gerald Münch; Björn Kuhla; Evgeny I Rogaev; Magdalini Tsolaki; Andreas Papassotiropoulos; Jürgen Götz
Role for glyoxalase I in Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(20):7687-92.
2004: Stephen R Robinson; Glenda M Bishop; Hyoung-gon Lee; Gerald Münch
Lessons from the AN 1792 Alzheimer vaccine: lest we forget.
Neurobiology of aging 2004;25(5):609-15.
2004: Ina Meiners; Sunna Hauschildt; Karen Nieber; Gerald Münch
Pentoxyphylline and propentophylline are inhibitors of TNF-alpha release in monocytes activated by advanced glycation endproducts.
Journal of neural transmission (Vienna, Austria : 1996) 2004;111(3):441-7.
2004: Björn Kuhla; Claudia Loske; S Garcia De Arriba; Reinhard Schinzel; J Huber; Gerald Münch
Differential effects of "Advanced glycation endproducts" and beta-amyloid peptide on glucose utilization and ATP levels in the neuronal cell line SH-SY5Y.
Journal of neural transmission (Vienna, Austria : 1996) 2004;111(3):427-39.
2003: Gerald Münch; Björn Kuhla; Hans-Joachim Lüth; Thomas Arendt; S R Robinson
Anti-AGEing defences against Alzheimer's disease.
Biochemical Society transactions 2003;31(Pt 6):1397-9.
2003: Susana Garcia de Arriba; Claudia Loske; Ina Meiners; Gerd Fleischer; Michael Lobisch; Klaus Wessel; Hans Tritschler; Reinhard Schinzel; Gerald Münch
Advanced glycation endproducts induce changes in glucose consumption, lactate production, and ATP levels in SH-SY5Y neuroblastoma cells by a redox-sensitive mechanism.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(11):1307-13.
2003: Sladjana Dukic-Stefanovic; Jovana Gasic-Milenkovic; Winnie Deuther-Conrad; Gerald Münch
Signal transduction pathways in mouse microglia N-11 cells activated by advanced glycation endproducts (AGEs).
Journal of neurochemistry 2003;87(1):44-55.
2003: Angela Galler; Grit Müller; Reinhard Schinzel; Jürgen Kratzsch; Wieland Kiess; Gerald Münch
Impact of metabolic control and serum lipids on the concentration of advanced glycation end products in the serum of children and adolescents with type 1 diabetes, as determined by fluorescence spectroscopy and nepsilon-(carboxymethyl)lysine ELISA.
Diabetes care 2003;26(9):2609-15.
2003: Gerald Münch; Jenny Apelt; Peter Stahl; Hans-Joachim Lüth; Reinhard Schliebs
Advanced glycation endproducts and pro-inflammatory cytokines in transgenic Tg2576 mice with amyloid plaque pathology.
Journal of neurochemistry 2003;86(2):283-9.
2003: Thomas Braun; Gerald Münch; Bettina Windmüller; Olaf Gevert; Matthias Laubender; Helmut Werner
Synthesis, molecular structure, and C-C coupling reactions of carbeneruthenium(II) complexes with C5H5Ru(=CRR') and C5Me5Ru(=CRR') as molecular units.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(11):2516-30.
2003: Gerald Münch; Jovana Gasic-Milenkovic; Sladjana Dukic-Stefanovic; Björn Kuhla; Katrin Heinrich; Peter Riederer; Henri Huttunen; Hank Founds; Gangadharan Sajithlal
Microglial activation induces cell death, inhibits neurite outgrowth and causes neurite retraction of differentiated neuroblastoma cells.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2003;150(1):1-8.
2003: Stephen R Robinson; Glenda M Bishop; Gerald Münch
Alzheimer vaccine: amyloid-beta on trial.
BioEssays : news and reviews in molecular, cellular and developmental biology 2003;25(3):283-8.
2003: Jovana Gasic-Milenkovic; Sladjana Dukic-Stefanovic; Winnie Deuther-Conrad; Ulrich Gärtner; Gerald Münch
Beta-amyloid peptide potentiates inflammatory responses induced by lipopolysaccharide, interferon -gamma and 'advanced glycation endproducts' in a murine microglia cell line.
The European journal of neuroscience 2003;17(4):813-21.
2003: Jovana Gasic-Milenkovic; Claudia Loske; Gerald Münch
Advanced glycation endproducts cause lipid peroxidation in the human neuronal cell line SH-SY5Y.
Journal of Alzheimer's disease : JAD 2003;5(1):25-30.
2003: Gerald Münch; Jovana Gasic-Milenkovic; Thomas Arendt
Effect of advanced glycation endproducts on cell cycle and their relevance for Alzheimer's disease.
Journal of neural transmission. Supplementum 2003;(65):63-71.
2002: Hans-Joachim Lüth; Gerald Münch; Thomas Arendt
Aberrant expression of NOS isoforms in Alzheimer's disease is structurally related to nitrotyrosine formation.
Brain research 2002;953(1-2):135-43.
2002: Sladjana Dukic-Stefanovic; Dorothee Schicktanz; Amanda Wong; Dieter Palm; Peter Riederer; Toshimitsu Niwa; Reinhard Schinzel; Gerald Münch
Characterization of antibody affinities using an AGE-modified dipeptide spot library.
Journal of immunological methods 2002;266(1-2):45-52.
2002: Gerald Münch; S R Robinson
Potential neurotoxic inflammatory responses to Abeta vaccination in humans.
Journal of neural transmission (Vienna, Austria : 1996) 2002;109(7-8):1081-7.
2002: D Allan Butterfield; Sue Griffin; Gerald Münch; Giulio Maria Pasinetti
Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists.
Journal of Alzheimer's disease : JAD 2002;4(3):193-201.
2002: Gerald Münch; Stephen R Robinson
Comment on Vicki Brower's article 'Harnessing the immune system to battle Alzheimer's' in EMBO reports, March 2002.
EMBO reports 2002;3(5):392.
2002: Gerald Münch; Claire E Shepherd; Heather McCann; William S Brooks; John B J Kwok; Thomas Arendt; Marianne Hallupp; Peter R Schofield; Ralph N Martins; Linda Truong
Intraneuronal advanced glycation endproducts in presenilin-1 Alzheimer's disease.
Neuroreport 2002;13(5):601-4.
2002: Gerald Münch; S R Robinson
Alzheimer's vaccine: a cure as dangerous as the disease?
Journal of neural transmission (Vienna, Austria : 1996) 2002;109(4):537-9.
2002: Gangadharan Sajithlal; Henri Huttunen; Heikki Rauvala; Gerald Münch
Receptor for advanced glycation end products plays a more important role in cellular survival than in neurite outgrowth during retinoic acid-induced differentiation of neuroblastoma cells.
The Journal of biological chemistry 2002;277(9):6888-97.
2002: Gerald Münch; Winnie Deuther-Conrad; Jovana Gasic-Milenkovic
Glycoxidative stress creates a vicious cycle of neurodegeneration in Alzheimer's disease--a target for neuroprotective treatment strategies?
Journal of neural transmission. Supplementum 2002;(62):303-7.
2001: Amanda Wong; Sladjana Dukic-Stefanovic; Jovana Gasic-Milenkovic; Reinhard Schinzel; H Wiesinger; Peter Riederer; Gerald Münch
Anti-inflammatory antioxidants attenuate the expression of inducible nitric oxide synthase mediated by advanced glycation endproducts in murine microglia.
The European journal of neuroscience 2001;14(12):1961-7.
2001: Jovana Gasic-Milenkovic; Claudia Loske; Winnie Deuther-Conrad; Gerald Münch
Protein "AGEing"--cytotoxicity of a glycated protein increases with its degree of AGE-modification.
Zeitschrift für Gerontologie und Geriatrie 2001;34(6):457-60.
2001: Amanda Wong; Hans-Joachim Lüth; Winnie Deuther-Conrad; Sladjana Dukic-Stefanovic; Jovana Gasic-Milenkovic; Thomas Arendt; Gerald Münch
Advanced glycation endproducts co-localize with inducible nitric oxide synthase in Alzheimer's disease.
Brain research 2001;920(1-2):32-40.
2001: Winnie Deuther-Conrad; Claudia Loske; Reinhard Schinzel; R Dringen; Peter Riederer; Gerald Münch
Advanced glycation endproducts change glutathione redox status in SH-SY5Y human neuroblastoma cells by a hydrogen peroxide dependent mechanism.
Neuroscience letters 2001;312(1):29-32.
2001: G Xiang; Reinhard Schinzel; Andreas Simm; Gerald Münch; Katarina Sebekova; M Kasper; Toshimitsu Niwa; C Schmitz; August Heidland
Advanced glycation end products (AGEs)-induced expression of TGF-beta 1 is suppressed by a protease in the tubule cell line LLC-PK1.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2001;16(8):1562-9.
2001: K Hager; A Marahrens; M Kenklies; Peter Riederer; Gerald Münch
Alpha-lipoic acid as a new treatment option for Alzheimer [corrected] type dementia.
Archives of gerontology and geriatrics 2001;32(3):275-82.
2001: Reinhard Schinzel; Gerald Münch; August Heidland; Katarina Sebekova
Advanced glycation end products in end-stage renal disease and their removal.
Nephron 2001;87(4):295-303.
2001: Sladjana Dukic-Stefanovic; Reinhard Schinzel; Peter Riederer; Gerald Münch
AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs?
Biogerontology 2001;2(1):19-34.
2000: Gerald Münch; Hans-Joachim Lüth; Amanda Wong; Thomas Arendt; E Hirsch; Rivka Ravid; Peter Riederer
Crosslinking of alpha-synuclein by advanced glycation endproducts--an early pathophysiological step in Lewy body formation?
Journal of chemical neuroanatomy 2000;20(3-4):253-7.
2000: Andrea Gerdemann; Horst-Dieter Lemke; A Nothdurft; August Heidland; Gerald Münch; Udo Bahner; Reinhard Schinzel
Low-molecular but not high-molecular advanced glycation end products (AGEs) are removed by high-flux dialysis.
Clinical nephrology 2000;54(4):276-83.
2000: Claudia Loske; Andrea Gerdemann; W Schepl; Matthias Wycislo; Reinhard Schinzel; Dieter Palm; Peter Riederer; Gerald Münch
Transition metal-mediated glycoxidation accelerates cross-linking of beta-amyloid peptide.
European journal of biochemistry / FEBS 2000;267(13):4171-8.
1999: Gerald Münch; D Schicktanz; A Behme; Manfred Gerlach; Peter Riederer; Dieter Palm; Reinhard Schinzel
Amino acid specificity of glycation and protein-AGE crosslinking reactivities determined with a dipeptide SPOT library.
Nature biotechnology 1999;17(10):1006-10.
1999: Michael Kasper; R Schinzel; T Niwa; Gerald Münch; Martin Witt; Heinz Fehrenbach; Michaela Wilsch-Bräuninger; K Pehlke; A Hofer; Richard H W Funk
Experimental induction of AGEs in fetal L132 lung cells changes the level of intracellular cathepsin D.
Biochemical and biophysical research communications 1999;261(1):175-82.
1999: Katarína Sebeková; Reinhard Schinzel; Gerald Münch; Z Krivosíková; R Dzúrik; August Heidland
Advanced glycation end-product levels in subtotally nephrectomized rats: beneficial effects of angiotensin II receptor 1 antagonist losartan.
Mineral and electrolyte metabolism 1999;25(4-6):380-3.
1999: A Neumann; Reinhard Schinzel; Dieter Palm; Peter Riederer; Gerald Münch
High molecular weight hyaluronic acid inhibits advanced glycation endproduct-induced NF-kappaB activation and cytokine expression.
FEBS letters 1999;453(3):283-7.
1999: Nuria Durany; Gerald Münch; Tanja M Michel; Peter Riederer
Investigations on oxidative stress and therapeutical implications in dementia.
European archives of psychiatry and clinical neuroscience 1999;249 Suppl 3():68-73.
1998: Katarína Sebeková; Reinhard Schinzel; H Ling; Andreas Simm; G Xiang; M Gekle; Gerald Münch; Spyros Vamvakas; August Heidland
Advanced glycated albumin impairs protein degradation in the kidney proximal tubules cell line LLC-PK1.
Cellular and molecular biology (Noisy-le-Grand, France) 1998;44(7):1051-60.
1998: Gerald Münch; C Colaco
Towards a new "AGE" of the chemistry and pathophysiology of the Maillard reaction.
Cellular and molecular biology (Noisy-le-Grand, France) 1998;44(7):ix-x.
1998: Gerald Münch; Manfred Gerlach; jeswinder sian; A Wong; Peter Riederer
Advanced glycation end products in neurodegeneration: more than early markers of oxidative stress?
Annals of neurology 1998;44(3 Suppl 1):S85-8.
1998: jeswinder sian; R Hensiek; Dieter Senitz; Gerald Münch; Kurt A Jellinger; Peter Riederer; Manfred Gerlach
A novel technique for the isolation of Lewy bodies in brain.
Acta neuropathologica 1998;96(2):111-5.
1998: Gerald Münch; A M Cunningham; Peter Riederer; Eva Braak
Advanced glycation endproducts are associated with Hirano bodies in Alzheimer's disease.
Brain research 1998;796(1-2):307-10.
1998: Jan Galle; R Schneider; Beate Winner; C Lehmann-Bodem; R Schinzel; Gerald Münch; E Conzelmann; Christoph Wanner
Glyc-oxidized LDL impair endothelial function more potently than oxidized LDL: role of enhanced oxidative stress.
Atherosclerosis 1998;138(1):65-77.
1998: K Weber; W Schmahl; Gerald Münch
Distribution of advanced glycation end products in the cerebellar neurons of dogs.
Brain research 1998;791(1-2):11-7.
1998: Claudia Loske; A Neumann; A M Cunningham; K Nichol; Reinhard Schinzel; Peter Riederer; Gerald Münch
Cytotoxicity of advanced glycation endproducts is mediated by oxidative stress.
Journal of neural transmission (Vienna, Austria : 1996) 1998;105(8-9):1005-15.
1998: August Heidland; Reinhard Schinzel; Katarina Sebekova; G Xiang; Gerald Münch; Andreas Simm
Advanced glycation endproducts and the kidney.
Przegla̧d lekarski 1998;55 Suppl 1():29-31.
1998: Wolfgang Retz; W Gsell; Gerald Münch; Michael Rösler; Peter Riederer
Free radicals in Alzheimer's disease.
Journal of neural transmission. Supplementum 1998;54():221-36.
1998: Gerald Münch; Reinhard Schinzel; Claudia Loske; A Wong; Nuria Durany; J J Li; H Vlassara; Mark A. Smith; George Perry; Peter Riederer
Alzheimer's disease--synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts.
Journal of neural transmission (Vienna, Austria : 1996) 1998;105(4-5):439-61.
1997: Gerald Münch; R Keis; A Wessels; Peter Riederer; Udo Bahner; August Heidland; T Niwa; Horst-Dieter Lemke; Reinhard Schinzel
Determination of advanced glycation end products in serum by fluorescence spectroscopy and competitive ELISA.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1997;35(9):669-77.
1997: Andreas Simm; Gerald Münch; F Seif; O Schenk; August Heidland; H Richter; Spyros Vamvakas; Reinhard Schinzel
Advanced glycation endproducts stimulate the MAP-kinase pathway in tubulus cell line LLC-PK1.
FEBS letters 1997;410(2-3):481-4.
1997: Gerald Münch; S Mayer; J Michaelis; Alan R Hipkiss; Peter Riederer; R Müller; A Neumann; Reinhard Schinzel; A M Cunningham
Influence of advanced glycation end-products and AGE-inhibitors on nucleation-dependent polymerization of beta-amyloid peptide.
Biochimica et biophysica acta 1997;1360(1):17-29.
1997: Gerald Münch; Johannes Thome; P Foley; Reinhard Schinzel; Peter Riederer
Advanced glycation endproducts in ageing and Alzheimer's disease.
Brain research. Brain research reviews 1997;23(1-2):134-43.
1996: Johannes Thome; J Kornhuber; Gerald Münch; Reinhard Schinzel; Y Taneli; B Zielke; Michael Rösler; Peter Riederer
[New hypothesis on etiopathogenesis of Alzheimer syndrome. Advanced glycation end products (AGEs)].
Der Nervenarzt 1996;67(11):924-9.
1996: Johannes Thome; Gerald Münch; R Müller; Reinhard Schinzel; J Kornhuber; D Blum-Degen; L Sitzmann; Michael Rösler; August Heidland; Peter Riederer
Advanced glycation endproducts-associated parameters in the peripheral blood of patients with Alzheimer's disease.
Life sciences 1996;59(8):679-85.
1994: Gerald Münch; J Lincoln; K I Maynard; A Belai; G Burnstock
Effects of acrylamide on cotransmission in perivascular sympathetic and sensory nerves.
Journal of the autonomic nervous system 1994;49(3):197-205.
1994: Gerald Münch; Y Taneli; E Schraven; U Schindler; Reinhard Schinzel; D Palm; Peter Riederer
The cognition-enhancing drug tenilsetam is an inhibitor of protein crosslinking by advanced glycosylation.
Journal of neural transmission. Parkinson's disease and dementia section 1994;8(3):193-208.
1993: D Malek; Gerald Münch; D Palm
Two sites in the third inner loop of the dopamine D2 receptor are involved in functional G protein-mediated coupling to adenylate cyclase.
FEBS letters 1993;325(3):215-9.
1991: Gerald Münch; Christian Dees; M Hekman; D Palm
Multisite contacts involved in coupling of the beta-adrenergic receptor with the stimulatory guanine-nucleotide-binding regulatory protein. Structural and functional studies by beta-receptor-site-specific synthetic peptides.
European journal of biochemistry / FEBS 1991;198(2):357-64.
1990: D Palm; Gerald Münch; D Malek; Christian Dees; M Hekman
Identification of a Gs-protein coupling domain to the beta-adrenoceptor using site-specific synthetic peptides. Carboxyl terminus of Gs alpha is involved in coupling to beta-adrenoceptors.
FEBS letters 1990;261(2):294-8.
1989: F G Dunkel; Gerald Münch; Fritz Boege; R Cantrill; N P Kurstjens
Proteolytic degradation routes for turkey beta 1-adrenoceptor probed with antipeptide antibodies against the N-terminal sequence of the receptor.
Biochemical and biophysical research communications 1989;165(1):264-70.
1989: D Palm; Gerald Münch; Christian Dees; M Hekman
Mapping of beta-adrenoceptor coupling domains to Gs-protein by site-specific synthetic peptides.
FEBS letters 1989;254(1-2):89-93.
1989: M Hekman; M Baumann; M Köstler; H Heithier; Gerald Münch; D Palm; E J Helmreich
Interaction of components of the adenylate cyclase system in the course of hormonal signal transmission.
Journal of protein chemistry 1989;8(3):404-5.