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Steven Mundt

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Chemicals & Drugs

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Liwen Zhang; Yuchen Zhou; Amber Ying Zhu; Martin S Springer; Magdalena Alonso-Galicia; Bruce L Daugherty; Ling Gao; Melba Hernandez; Xiang-qing Li; JeanMarie Lisnock; Steven S Mundt; Edward A O'Neill; Oscar Puig
Metabolic syndrome in mice induced by expressing a transcriptional activator in adipose tissue.
Milana Maletic; Aaron Leeman; Michael Szymonifka; Steven S Mundt; Hratch J Zokian; Kashmira Shah; Jasminka Dragovic; Kathy Lyons; Rolf Thieringer; Anne H Vosatka; James M Balkovec; Sherman Waddell
Bicyclo[2.2.2]octyltriazole inhibitors of 11β-hydoxysteroid dehydrogenase type 1. Pharmacological agents for the treatment of metabolic syndrome.
Wanying Sun; Milana Maletic; Steven S Mundt; Kashmira Shah; Hratch Zokian; Kathy Lyons; Sherman T Waddell; James M Balkovec
Substituted phenyl triazoles as selective inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1.

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All Publications

2012: Liwen Zhang; Yuchen Zhou; Amber Ying Zhu; Martin S Springer; Magdalena Alonso-Galicia; Bruce L Daugherty; Ling Gao; Melba Hernandez; Xiang-qing Li; JeanMarie Lisnock; Steven S Mundt; Edward A O'Neill; Oscar Puig
Metabolic syndrome in mice induced by expressing a transcriptional activator in adipose tissue.
Transgenic research 2012;21(3):633-44.
2011: Milana Maletic; Aaron Leeman; Michael Szymonifka; Steven S Mundt; Hratch J Zokian; Kashmira Shah; Jasminka Dragovic; Kathy Lyons; Rolf Thieringer; Anne H Vosatka; James M Balkovec; Sherman Waddell
Bicyclo[2.2.2]octyltriazole inhibitors of 11β-hydoxysteroid dehydrogenase type 1. Pharmacological agents for the treatment of metabolic syndrome.
Bioorganic & medicinal chemistry letters 2011;21(8):2568-72.
2011: Wanying Sun; Milana Maletic; Steven S Mundt; Kashmira Shah; Hratch Zokian; Kathy Lyons; Sherman T Waddell; James M Balkovec
Substituted phenyl triazoles as selective inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1.
Bioorganic & medicinal chemistry letters 2011;21(7):2141-5.
2008: Yuping Zhu; Steven H Olson; Donald Graham; Gool Patel; Anne Hermanowski-Vosatka; Steven S Mundt; Kashmira Shah; Marty Springer; Rolf Thieringer; Samuel Wright; Jianying Xiao; Hratch Zokian; Jasminka Dragovic; James M Balkovec
Phenylcyclobutyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
Bioorganic & medicinal chemistry letters 2008;18(11):3412-6.
2008: Yuping Zhu; Steven H Olson; Anne Hermanowski-Vosatka; Steven S Mundt; Kashmira Shah; Marty Springer; Rolf Thieringer; Samuel Wright; Jianying Xiao; Hratch Zokian; James M Balkovec
4-Methyl-5-phenyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
Bioorganic & medicinal chemistry letters 2008;18(11):3405-11.
2008: Susan D Aster; Donald W Graham; Divya Kharbanda; Gool Patel; Mitree Ponpipom; Gina M Santorelli; Michael J Szymonifka; Steven S Mundt; Kashmira Shah; Martin S Springer; Rolf Thieringer; Anne Hermanowski-Vosatka; Samuel D Wright; Jianying Xiao; Hratch Zokian; James M Balkovec
Bis-aryl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.
Bioorganic & medicinal chemistry letters 2008;18(9):2799-804.
2005: Xin Gu; Jasminka Dragovic; Gloria C Koo; Sam L Koprak; Cheryl LeGrand; Steven S Mundt; Kashmira Shah; Martin S Springer; Eugene Y Tan; Rolf Thieringer; Anne Hermanowski-Vosatka; Hratch J Zokian; James M Balkovec; Sherman T Waddell
Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11beta-HSD1: novel therapeutic agents for the treatment of metabolic syndrome.
Bioorganic & medicinal chemistry letters 2005;15(23):5266-9.
2005: Steven Olson; Susan D Aster; Kai Brown; Linda Carbin; Donald W Graham; Anne Hermanowski-Vosatka; Cheryl B LeGrand; Steven S Mundt; Michael A Robbins; James M Schaeffer; Llnon H Slossberg; Michael J Szymonifka; Rolf Thieringer; Samuel D Wright; James M Balkovec
Adamantyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.
Bioorganic & medicinal chemistry letters 2005;15(19):4359-62.
2005: Anne Hermanowski-Vosatka; James M Balkovec; Kang Cheng; Howard Y Chen; Melba Hernandez; Gloria C Koo; Cheryl B Le Grand; Zhihua Li; Joseph M Metzger; Steven S Mundt; Heather Noonan; Christian N Nunes; Steven H Olson; Bill Pikounis; Ning Ren; Nancy Robertson; James M Schaeffer; Kashmira Shah; Martin S Springer; Alison M Strack; Matthias Strowski; Kenneth Wu; Tsueiju Wu; Jianying Xiao; Bei B Zhang; Samuel D Wright; Rolf Thieringer
11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice.
The Journal of experimental medicine 2005;202(4):517-27.
2005: Kelli Solly; Steven S Mundt; Hratch J Zokian; Gloria Juy-Fang Ding; Anne Hermanowski-Vosatka; Berta Strulovici; Wei Zheng
High-throughput screening of 11beta-hydroxysteroid dehydrogenase type 1 in scintillation proximity assay format.
Assay and drug development technologies 2005;3(4):377-84.
2005: Steven S Mundt; Kelli Solly; Rolf Thieringer; Anne Hermanowski-Vosatka
Development and application of a scintillation proximity assay (SPA) for identification of selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.
Assay and drug development technologies 2005;3(4):367-75.
2002: Hélène Duez; Yu-Sheng Chao; Melba Hernandez; Gérard Torpier; Philippe Poulain; Steven S Mundt; Ziad Mallat; Elisabeth Teissier; Charlotte A Burton; Alain Tedgui; Jean-Charles Fruchart; Catherine Fiévet; Samuel D Wright; Bart Staels
Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice.
The Journal of biological chemistry 2002;277(50):48051-7.
2002: Charlotte A Burton; Sushma Patel; Steven S Mundt; Heide Hassing; Donghui Zhang; Anne Hermanowski-Vosatka; Samuel D Wright; Yu-Sheng Chao; Patricia A Detmers; Carl P Sparrow
Deficiency in sPLA(2) does not affect HDL levels or atherosclerosis in mice.
Biochemical and biophysical research communications 2002;294(1):88-94.
2001: Sushma Patel; E M Thelander; Melba Hernandez; J Montenegro; Heide Hassing; C Burton; Steven S Mundt; Anne Hermanowski-Vosatka; Samuel D Wright; Yu-Sheng Chao; Patricia A Detmers
ApoE(-/-) mice develop atherosclerosis in the absence of complement component C5.
Biochemical and biophysical research communications 2001;286(1):164-70.
2001: Tian-Quan Cai; Birming Wong; Steven S Mundt; Rolf Thieringer; Samuel D Wright; Anne Hermanowski-Vosatka
Induction of 11beta-hydroxysteroid dehydrogenase type 1 but not -2 in human aortic smooth muscle cells by inflammatory stimuli.
The Journal of steroid biochemistry and molecular biology 2001;77(2-3):117-22.
2001: Carl P Sparrow; Charlotte A Burton; Melba Hernandez; Steven S Mundt; Heide Hassing; S Patel; R Rosa; Anne Hermanowski-Vosatka; Pei-ran Wang; D Zhang; L Peterson; Patricia A Detmers; Yu-Sheng Chao; Samuel D Wright
Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(1):115-21.
2000: Anne Hermanowski-Vosatka; David Gerhold; Steven S Mundt; V A Loving; M Lu; Y Chen; Alex Elbrecht; M Wu; Thomas W Doebber; L Kelly; Denise P Milot; Qiu Guo; Pei-ran Wang; Marc C Ippolito; Yu-Sheng Chao; Samuel D Wright; Rolf Thieringer
PPARalpha agonists reduce 11beta-hydroxysteroid dehydrogenase type 1 in the liver.
Biochemical and biophysical research communications 2000;279(2):330-6.
2000: Patricia A Detmers; Melba Hernandez; John S Mudgett; Heide Hassing; Charlotte Burton; Steven S Mundt; S Chun; D Fletcher; Deborah Card; JeanMarie Lisnock; R Weikel; James Bergstrom; D E Shevell; Anne Hermanowski-Vosatka; Carl P Sparrow; Yu-Sheng Chao; D J Rader; Samuel D Wright; Ellen Puré
Deficiency in inducible nitric oxide synthase results in reduced atherosclerosis in apolipoprotein E-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3430-5.
2000: Samuel D Wright; C Burton; Melba Hernandez; Heide Hassing; J Montenegro; Steven S Mundt; S Patel; Deborah Card; Anne Hermanowski-Vosatka; James Bergstrom; Carl P Sparrow; Patricia A Detmers; Yu-Sheng Chao
Infectious agents are not necessary for murine atherogenesis.
The Journal of experimental medicine 2000;191(8):1437-42.
1999: Anne Hermanowski-Vosatka; Steven S Mundt; Julia Ayala; S Goyal; William A Hanlon; Robert M Czerwinski; S D Wright; Christian P Whitman
Enzymatically inactive macrophage migration inhibitory factor inhibits monocyte chemotaxis and random migration.
Biochemistry 1999;38(39):12841-9.