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Gregory Mundy

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James R Edwards; Linda Connelly; Nicole Fleming; Seint T Lwin; Megan M Moore; Gregory R Mundy; Jeffry S Nyman; Koichiro Ono; Daniel S Perrien; Fiona E Yull; Florent Elefteriou
Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling.
Toru Hiraga; Yoshihiro Morita; Gregory R Mundy; Akira Myoui; Clifford J Rosen; Akira Sasaki; Nobuyuki Hashimoto; Kenji Hata; Hideki Yoshikawa; Toshiyuki Yoneda
Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases.
Jessica A Fowler; Robert A Kyle; Seint T Lwin; Gregory R Mundy; Matthew T Drake; James R Edwards; Claire M Edwards
Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease.

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2013: James R Edwards; Linda Connelly; Nicole Fleming; Seint T Lwin; Megan M Moore; Gregory R Mundy; Jeffry S Nyman; Koichiro Ono; Daniel S Perrien; Fiona E Yull; Florent Elefteriou
Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013;28(4):960-9.
2012: Toru Hiraga; Yoshihiro Morita; Gregory R Mundy; Akira Myoui; Clifford J Rosen; Akira Sasaki; Nobuyuki Hashimoto; Kenji Hata; Hideki Yoshikawa; Toshiyuki Yoneda
Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases.
Cancer research 2012;72(16):4238-49.
2011: Jessica A Fowler; Robert A Kyle; Seint T Lwin; Gregory R Mundy; Matthew T Drake; James R Edwards; Claire M Edwards
Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease.
Blood 2011;118(22):5872-82.
2011: Rachelle W Johnson; Alyssa R Merkel; Gregory R Mundy; Mai P Nguyen; Sabrina Danilin; Julie A Sterling
6-Thioguanine inhibition of parathyroid hormone-related protein expression is mediated by GLI2.
Anticancer research 2011;31(9):2705-12.
2011: Jeffry S Nyman; Conor C Lynch; Daniel S Perrien; Sophie Thiolloy; Elizabeth C O'Quinn; Chetan A Patil; Xiaohong Bi; George M Pharr; Anita Mahadevan-Jansen; Gregory R Mundy
Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(6):1252-60.
2011: Rachelle W Johnson; Mai P Nguyen; Susan Padalecki; Barry Grubbs; Alyssa R Merkel; Babatunde Oyajobi; Lynn M Matrisian; Gregory R Mundy; Julie A Sterling
TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling.
Cancer research 2011;71(3):822-31.
2011: Lindsay C Johnson; Rachelle W Johnson; Steve A Munoz; Gregory R Mundy; Todd E Peterson; Julie A Sterling
Longitudinal live animal micro-CT allows for quantitative analysis of tumor-induced bone destruction.
Bone 2011;48(1):141-51.
2011: Julie A Sterling; James R Edwards; T John Martin; Gregory R Mundy
Advances in the biology of bone metastasis: how the skeleton affects tumor behavior.
Bone 2011;48(1):6-15.
2010: James R Edwards; Jeffry S Nyman; Seint T Lwin; Megan M Moore; Javier Esparza; Elizabeth C O'Quinn; Andrew J Hart; Swati Biswas; Chetan A Patil; Scott Lonning; Anita Mahadevan-Jansen; Gregory R Mundy
Inhibition of TGF-β signaling by 1D11 antibody treatment increases bone mass and quality in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(11):2419-26.
2010: Li Yang; Claire M Edwards; Gregory R Mundy
Gr-1+CD11b+ myeloid-derived suppressor cells: formidable partners in tumor metastasis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(8):1701-6.
2010: Toshitaka Yoshii; Andrea E Hafeman; Jeffry S Nyman; Javier M Esparza; Kenichi Shinomiya; Dan M Spengler; Gregory R Mundy; Gloria E Gutierrez; Scott A Guelcher
A sustained release of lovastatin from biodegradable, elastomeric polyurethane scaffolds for enhanced bone regeneration.
Tissue engineering. Part A 2010;16(7):2369-79.
2010: Weixi Wang; Jeffry S Nyman; Heather E Moss; Gloria Gutierrez; Gregory R Mundy; Xiangli Yang; Florent Elefteriou
Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(7):1658-67.
2010: Nazanin S Ruppender; Alyssa R Merkel; T John Martin; Gregory R Mundy; Julie A Sterling; Scott A Guelcher
Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells.
PloS one 2010;5(11):e15451.
2009: Jessica A Fowler; Gregory R Mundy; Seint T Lwin; Conor C Lynch; Claire M Edwards
A murine model of myeloma that allows genetic manipulation of the host microenvironment.
Disease models & mechanisms 2009;2(11-12):604-11.
2009: Sophie Thiolloy; Jennifer Halpern; Ginger E Holt; Herbert S Schwartz; Gregory R Mundy; Lynn M Matrisian; Conor C Lynch
Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis.
Cancer research 2009;69(16):6747-55.
2009: Jeffry S Nyman; Steve Munoz; Satyawan Jadhav; Alfred Mansour; Toshitaka Yoshii; Gregory R Mundy; Gloria E Gutierrez
Quantitative measures of femoral fracture repair in rats derived by micro-computed tomography.
Journal of biomechanics 2009;42(7):891-7.
2009: Claire M Edwards; Seint T Lwin; Jessica A Fowler; Babatunde Oyajobi; Junling Zhuang; Andreia L Bates; Gregory R Mundy
Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo.
American journal of hematology 2009;84(5):268-72.
2008: Claire M Edwards; Junling Zhuang; Gregory R Mundy
The pathogenesis of the bone disease of multiple myeloma.
Bone 2008;42(6):1007-13.
2008: Gregory R Mundy; xiangli yang
Hedgehog coordination of postnatal osteoclast and osteoblast activities.
Developmental cell 2008;14(5):637-8.
2008: Claire M Edwards; James R Edwards; Seint T Lwin; Javier Esparza; Babatunde Oyajobi; Brandon McCluskey; Steven Munoz; Barry Grubbs; Gregory R Mundy
Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo.
Blood 2008;111(5):2833-42.
2008: Claire M Edwards; Gregory R Mundy
Eph receptors and ephrin signaling pathways: a role in bone homeostasis.
International journal of medical sciences 2008;5(5):263-72.
2007: Babatunde Oyajobi; I Ross Garrett; Anjana Gupta; Alda Flores; Javier Esparza; Steve Muñoz; Ming Zhao; Gregory R Mundy
Stimulation of new bone formation by the proteasome inhibitor, bortezomib: implications for myeloma bone disease.
British journal of haematology 2007;139(3):434-8.
2007: I Ross Garrett; Gloria E Gutierrez; Gianni Rossini; J Nyman; B McCluskey; A Flores; Gregory R Mundy
Locally delivered lovastatin nanoparticles enhance fracture healing in rats.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2007;25(10):1351-7.
2007: Babatunde Oyajobi; Steve Muñoz; Rami Kakonen; Paul J Williams; Anjana Gupta; Christi L Wideman; Beryl Story; Barry Grubbs; Allison Armstrong; William C Dougall; I Ross Garrett; Gregory R Mundy
Detection of myeloma in skeleton of mice by whole-body optical fluorescence imaging.
Molecular cancer therapeutics 2007;6(6):1701-8.
2007: Yingpei Zhang; Susan Padalecki; Asish Chaudhuri; Eric De Waal; Beth Goins; Barry Grubbs; Yuji Ikeno; Arlan G Richardson; Gregory R Mundy; Brian Herman
Caspase-2 deficiency enhances aging-related traits in mice.
Mechanisms of ageing and development 2007;128(2):213-21.
2006: Julie A Sterling; Babatunde Oyajobi; Barry Grubbs; Susan Padalecki; Steve A Munoz; Anjana Gupta; Beryl Story; Ming Zhao; Gregory R Mundy
The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells.
Cancer research 2006;66(15):7548-53.
2006: Ming Zhao; Mei Qiao; Stephen E Harris; Di Chen; Babatunde Oyajobi; Gregory R Mundy
The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling.
Molecular and cellular biology 2006;26(16):6197-208.
2006: Abhik Bandyopadhyay; Joseph Agyin; Long Wang; Yuping Tang; Xiufen Lei; Beryl Story; John Cornell; Bradley Pollock; Gregory R Mundy; Luzhe Sun
Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor.
Cancer research 2006;66(13):6714-21.
2006: Gregory R Mundy
Nutritional modulators of bone remodeling during aging.
The American journal of clinical nutrition 2006;83(2):427S-430S.
2006: Gloria E Gutierrez; D Lalka; I Ross Garrett; Gianni Rossini; Gregory R Mundy
Transdermal application of lovastatin to rats causes profound increases in bone formation and plasma concentrations.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2006;17(7):1033-42.
2005: Claire M Shipman; Babatunde Oyajobi; Gregory R Mundy
Advances in the management of myeloma bone disease.
Expert opinion on pharmacotherapy 2005;6(16):2781-91.
2005: Gregory R Mundy
How can bone turnover markers be best utilized for prediction of skeletal events in patients with solid tumors?
Nature clinical practice. Oncology 2005;2(5):242-3.
2005: Peter S N Rowe; I Ross Garrett; Patricia M Schwarz; David L Carnes; Eileen M Lafer; Gregory R Mundy; Gloria E Gutierrez
Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP).
Bone 2005;36(1):33-46.
2004: Yoshihisa Mori; Nobuaki Shimizu; Mark Dallas; Maryla Niewolna; Beryl Story; Paul J Williams; Gregory R Mundy; Toshiyuki Yoneda
Anti-alpha4 integrin antibody suppresses the development of multiple myeloma and associated osteoclastic osteolysis.
Blood 2004;104(7):2149-54.
2004: Gregory R Mundy
The evolving role of bisphosphonates: cancer treatment-induced bone loss.
Oncology (Williston Park, N.Y.) 2004;18(5 Suppl 3):9-10.
2004: Ming Zhao; Mei Qiao; Stephen E Harris; Babatunde Oyajobi; Gregory R Mundy; Di Chen
Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo.
The Journal of biological chemistry 2004;279(13):12854-9.
2004: Peter S N Rowe; Y Kumagai; Gloria E Gutierrez; I Ross Garrett; R Blacher; D Rosen; J Cundy; S Navvab; Di Chen; Marc K Drezner; L D Quarles; Gregory R Mundy
MEPE has the properties of an osteoblastic phosphatonin and minhibin.
Bone 2004;34(2):303-19.
2003: Akira Myoui; Riko Nishimura; Paul J Williams; Toru Hiraga; Daisuke Tamura; Toshimi Michigami; Gregory R Mundy; Toshiyuki Yoneda
C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis.
Cancer research 2003;63(16):5028-33.
2003: Jian Q Feng; Lianping Xing; Jiang-Hong Zhang; Ming Zhao; Diane Horn; Jeannie Chan; Brendan F Boyce; Stephen E Harris; Gregory R Mundy; Di Chen
NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro.
The Journal of biological chemistry 2003;278(31):29130-5.
2003: Ming Zhao; Mei Qiao; Babatunde Oyajobi; Gregory R Mundy; Di Chen
E3 ubiquitin ligase Smurf1 mediates core-binding factor alpha1/Runx2 degradation and plays a specific role in osteoblast differentiation.
The Journal of biological chemistry 2003;278(30):27939-44.
2003: Babatunde Oyajobi; Giovanni Franchin; Paul J Williams; Donna Pulkrabek; Anjana Gupta; Steve Munoz; Barry Grubbs; Ming Zhao; Di Chen; Barbara Sherry; Gregory R Mundy
Dual effects of macrophage inflammatory protein-1alpha on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease.
Blood 2003;102(1):311-9.
2003: I Ross Garrett; Di Chen; Gloria E Gutierrez; Ming Zhao; A Escobedo; Gianni Rossini; Stephen E Harris; W Gallwitz; K B Kim; S Hu; C M Crews; Gregory R Mundy
Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro.
The Journal of clinical investigation 2003;111(11):1771-82.
2003: Sanna-Maria Käkönen; Gregory R Mundy
Mechanisms of osteolytic bone metastases in breast carcinoma.
Cancer 2003;97(3 Suppl):834-9.
2003: Babatunde Oyajobi; Gregory R Mundy
Receptor activator of NF-kappaB ligand, macrophage inflammatory protein-1alpha, and the proteasome: novel therapeutic targets in myeloma.
Cancer 2003;97(3 Suppl):813-7.
2002: Toshimi Michigami; Toru Hiraga; Paul J Williams; Maryla Niewolna; Riko Nishimura; Gregory R Mundy; Toshiyuki Yoneda
The effect of the bisphosphonate ibandronate on breast cancer metastasis to visceral organs.
Breast cancer research and treatment 2002;75(3):249-58.
2002: Gregory R Mundy
Metastasis to bone: causes, consequences and therapeutic opportunities.
Nature reviews. Cancer 2002;2(8):584-93.
2002: Sarah L Dallas; Jennifer L Rosser; Gregory R Mundy; Lynda F Bonewald
Proteolysis of latent transforming growth factor-beta (TGF-beta )-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix.
The Journal of biological chemistry 2002;277(24):21352-60.
2002: Ming Zhao; Stephen E Harris; Diane Horn; Zhaopo Geng; Riko Nishimura; Gregory R Mundy; Di Chen
Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation.
The Journal of cell biology 2002;157(6):1049-60.
2001: Nandini Ghosh-Choudhury; Goutam Ghosh Choudhury; Marie A Harris; John M Wozney; Gregory R Mundy; Sherry L Abboud; Stephen E Harris
Autoregulation of mouse BMP-2 gene transcription is directed by the proximal promoter element.
Biochemical and biophysical research communications 2001;286(1):101-8.
2001: Gregory R Mundy
Preclinical models of bone metastases.
Seminars in oncology 2001;28(4 Suppl 11):2-8.
2001: Toru Hiraga; Paul J Williams; Gregory R Mundy; Toshiyuki Yoneda
The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases.
Cancer research 2001;61(11):4418-24.
2001: I Ross Garrett; Gloria E Gutierrez; Gregory R Mundy
Statins and bone formation.
Current pharmaceutical design 2001;7(8):715-36.
2001: Gregory R Mundy; Toshiyuki Yoneda; T Hiraga
Preclinical studies with zoledronic acid and other bisphosphonates: impact on the bone microenvironment.
Seminars in oncology 2001;28(2 Suppl 6):35-44.
2001: Babatunde Oyajobi; D M Anderson; K Traianedes; Paul J Williams; Toshiyuki Yoneda; Gregory R Mundy
Therapeutic efficacy of a soluble receptor activator of nuclear factor kappaB-IgG Fc fusion protein in suppressing bone resorption and hypercalcemia in a model of humoral hypercalcemia of malignancy.
Cancer research 2001;61(6):2572-8.
2001: Gregory R Mundy; Di Chen; Ming Zhao; Sarah L Dallas; C Xu; Stephen E Harris
Growth regulatory factors and bone.
Reviews in endocrine & metabolic disorders 2001;2(1):105-15.
2000: Toshimi Michigami; N Shimizu; Paul J Williams; Maryla Niewolna; Sarah L Dallas; Gregory R Mundy; Toshiyuki Yoneda
Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4)beta(1)-integrin enhances production of osteoclast-stimulating activity.
Blood 2000;96(5):1953-60.
2000: Babatunde Oyajobi; Jian-Hong Deng; Sarah L Dallas; Hal B Jenson; Gregory R Mundy; Shou-Jiang Gao
Absence of herpesvirus DNA sequences in the 5T murine model of human multiple myeloma.
British journal of haematology 2000;109(2):413-9.
2000: Sarah L Dallas; Douglas R Keene; S P Bruder; J Saharinen; L Y Sakai; Gregory R Mundy; Lynda F Bonewald
Role of the latent transforming growth factor beta binding protein 1 in fibrillin-containing microfibrils in bone cells in vitro and in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(1):68-81.
1999: Gregory R Mundy; R Garrett; Stephen E Harris; J Chan; Di Chen; Gianni Rossini; B Boyce; Ming Zhao; Gloria E Gutierrez
Stimulation of bone formation in vitro and in rodents by statins.
Science (New York, N.Y.) 1999;286(5446):1946-9.
1999: Gregory R Mundy; Theresa A Guise
Hormonal control of calcium homeostasis.
Clinical chemistry 1999;45(8 Pt 2):1347-52.
1999: C R Dunstan; R Boyce; B F Boyce; I Ross Garrett; E Izbicka; W H Burgess; Gregory R Mundy
Systemic administration of acidic fibroblast growth factor (FGF-1) prevents bone loss and increases new bone formation in ovariectomized rats.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(6):953-9.
1999: Gregory R Mundy
Bisphosphonates as cancer drugs.
Hospital practice (1995) 1999;34(5):81-4, 88-9, 93-4.
1999: Gregory R Mundy
Cellular and molecular regulation of bone turnover.
Bone 1999;24(5 Suppl):35S-38S.
1999: Sarah L Dallas; I Ross Garrett; Babatunde Oyajobi; Mark Dallas; B F Boyce; F Bauss; J Radl; Gregory R Mundy
Ibandronate reduces osteolytic lesions but not tumor burden in a murine model of myeloma bone disease.
Blood 1999;93(5):1697-706.
1999: Gregory R Mundy
What can we learn from bone biology for the treatment for osteoporosis?
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1999;9 Suppl 2():S40-7.
1999: Juan Juan Yin; Katri S Selander; John M Chirgwin; Mark Dallas; Barry Grubbs; R Wieser; J Massagué; Gregory R Mundy; Theresa A Guise
TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development.
The Journal of clinical investigation 1999;103(2):197-206.
1998: Di Chen; X Ji; Marie A Harris; Jian Q Feng; Gerard Karsenty; Arkady Celeste; Vicki Rosen; Gregory R Mundy; Stephen E Harris
Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages.
The Journal of cell biology 1998;142(1):295-305.
1998: K Traianedes; Mark Dallas; I Ross Garrett; Gregory R Mundy; Lynda F Bonewald
5-Lipoxygenase metabolites inhibit bone formation in vitro.
Endocrinology 1998;139(7):3178-84.
1998: G Mbalaviele; Riko Nishimura; A Myoi; Maryla Niewolna; Sakamuri V Reddy; Di Chen; J Feng; D Roodman; Gregory R Mundy; Toshiyuki Yoneda
Cadherin-6 mediates the heterotypic interactions between the hemopoietic osteoclast cell lineage and stromal cells in a murine model of osteoclast differentiation.
The Journal of cell biology 1998;141(6):1467-76.
1998: Riko Nishimura; K Moriyama; K Yasukawa; Gregory R Mundy; Toshiyuki Yoneda
Combination of interleukin-6 and soluble interleukin-6 receptors induces differentiation and activation of JAK-STAT and MAP kinase pathways in MG-63 human osteoblastic cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(5):777-85.
1998: Gregory R Mundy
Myeloma bone disease.
European journal of cancer (Oxford, England : 1990) 1998;34(2):246-51.
1998: Theresa A Guise; Gregory R Mundy
Cancer and bone.
Endocrine reviews 1998;19(1):18-54.
1998: Riko Nishimura; Y Kato; Di Chen; Stephen E Harris; Gregory R Mundy; Toshiyuki Yoneda
Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12.
The Journal of biological chemistry 1998;273(4):1872-9.
1997: Y Kato; Jolene J Windle; BA Koop; Gregory R Mundy; Lynda F Bonewald
Establishment of an osteocyte-like cell line, MLO-Y4.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(12):2014-23.
1997: Gregory R Mundy
Mechanisms of bone metastasis.
Cancer 1997;80(8 Suppl):1546-56.
1997: Gregory R Mundy; T A Guise
Hypercalcemia of malignancy.
The American journal of medicine 1997;103(2):134-45.
1997: H L Uy; Gregory R Mundy; BF Boyce; Beryl Story; C R Dunstan; Juan Juan Yin; David G Roodman; Theresa A Guise
Tumor necrosis factor enhances parathyroid hormone-related protein-induced hypercalcemia and bone resorption without inhibiting bone formation in vivo.
Cancer research 1997;57(15):3194-9.
1997: I Ross Garrett; Sarah L Dallas; J Radl; Gregory R Mundy
A murine model of human myeloma bone disease.
Bone 1997;20(6):515-20.
1997: Toshiyuki Yoneda; Akira Sasaki; C Dunstan; Paul J Williams; F Bauss; Y A De Clerck; Gregory R Mundy
Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.
The Journal of clinical investigation 1997;99(10):2509-17.
1997: Gregory R Mundy
Malignancy and the skeleton.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1997;29(3):120-7.
1997: Di Chen; Marie A Harris; G Rossini; C R Dunstan; Sarah L Dallas; Jian Q Feng; Gregory R Mundy; Stephen E Harris
Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts.
Calcified tissue international 1997;60(3):283-90.
1997: Nandini Ghosh-Choudhury; Marie A Harris; John M Wozney; Gregory R Mundy; Stephen E Harris
Clonal osteoblastic cell lines from p53 null mouse calvariae are immortalized and dependent on bone morphogenetic protein 2 for mature osteoblastic phenotype.
Biochemical and biophysical research communications 1997;231(1):196-202.
1997: E Izbicka; C R Dunstan; D Horn; M Harris; Stephen E Harris; R Adams; Gregory R Mundy
Effects of human tumor cell lines on local new bone formation in vivo.
Calcified tissue international 1997;60(2):210-5.
1997: E Izbicka; C R Dunstan; D Horn; R Adams; Gregory R Mundy
Mitogenic lectin concanavalin A induces calvarial bone formation in vivo via indomethacin-sensitive pathway.
Calcified tissue international 1997;60(2):204-9.
1997: Lynda F Bonewald; R O Oreffo; C H Lee; S Park-Snyder; D Twardzik; Gregory R Mundy
Effects of retinol on activation of latent transforming growth factor-beta by isolated osteoclasts.
Endocrinology 1997;138(2):657-66.
1997: Jian Q Feng; D Chen; Nandini Ghosh-Choudhury; J Esparza; Gregory R Mundy; Stephen E Harris
Bone morphogenetic protein 2 transcripts in rapidly developing deer antler tissue contain an extended 5' non-coding region arising from a distal promoter.
Biochimica et biophysica acta 1997;1350(1):47-52.
1997: Lynda F Bonewald; M Flynn; M Qiao; Mark Dallas; Gregory R Mundy; B F Boyce
Mice lacking 5-lipoxygenase have increased cortical bone thickness.
Advances in experimental medicine and biology 1997;433():299-302.
1996: C Garcia; B F Boyce; J Gilles; Mark Dallas; M Qiao; Gregory R Mundy; Lynda F Bonewald
Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(11):1619-27.
1996: David Hughes; A Dai; John Tiffee; H H Li; Gregory R Mundy; B F Boyce
Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta.
Nature medicine 1996;2(10):1132-6.
1996: Theresa A Guise; Juan Juan Yin; S D Taylor; Y Kumagai; Mark Dallas; B F Boyce; Toshiyuki Yoneda; Gregory R Mundy
Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis.
The Journal of clinical investigation 1996;98(7):1544-9.
1996: Elzbieta Izbicka; Toshiyuki Yoneda; Y Takaoka; D Horn; P Williams; Gregory R Mundy
Identification of a novel bone/calcium metabolism-regulating factor in porcine pancreas.
The Journal of biological chemistry 1996;271(38):23230-4.
1996: G Mbalaviele; C R Dunstan; Akira Sasaki; Paul J Williams; Gregory R Mundy; Toshiyuki Yoneda
E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model.
Cancer research 1996;56(17):4063-70.
1996: Theresa A Guise; Gregory R Mundy
Physiological and pathological roles of parathyroid hormone-related peptide.
Current opinion in nephrology and hypertension 1996;5(4):307-15.
1996: K Moriyama; Paul J Williams; M Niewolna; Mark Dallas; Y Uehara; Gregory R Mundy; Toshiyuki Yoneda
Herbimycin A, a tyrosine kinase inhibitor, impairs hypercalcemia associated with a human squamous cancer producing interleukin-6 in nude mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(7):905-11.
1996: Gregory R Mundy
Osteoporosis into the year 2010.
British journal of obstetrics and gynaecology 1996;103 Suppl 13():32-7; discussion 37-8.
1996: C Garcia; M Qiao; D Chen; M Kirchen; W Gallwitz; Gregory R Mundy; Lynda F Bonewald
Effects of synthetic peptido-leukotrienes on bone resorption in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(4):521-9.
1996: Gregory R Mundy
Regulation of bone formation by bone morphogenetic proteins and other growth factors.
Clinical orthopaedics and related research 1996;(324):24-8.
1996: M Alsina; B Boyce; R D Devlin; J L Anderson; F Craig; Gregory R Mundy; David G Roodman
Development of an in vivo model of human multiple myeloma bone disease.
Blood 1996;87(4):1495-501.
1996: Elzbieta Izbicka; C Dunstan; J Esparza; C Jacobs; M Sabatini; Gregory R Mundy
Human amniotic tumor that induces new bone formation in vivo produces growth-regulatory activity in vitro for osteoblasts identified as an extended form of basic fibroblast growth factor.
Cancer research 1996;56(3):633-6.
1996: Nandini Ghosh-Choudhury; Jolene J Windle; BA Koop; Marie A Harris; D L Guerrero; John M Wozney; Gregory R Mundy; Stephen E Harris
Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic mice.
Endocrinology 1996;137(1):331-9.
1995: Jian Q Feng; D Chen; A J Cooney; M J Tsai; M A Harris; S Y Tsai; M Feng; Gregory R Mundy; Stephen E Harris
The mouse bone morphogenetic protein-4 gene. Analysis of promoter utilization in fetal rat calvarial osteoblasts and regulation by COUP-TFI orphan receptor.
The Journal of biological chemistry 1995;270(47):28364-73.
1995: David Hughes; Kenneth Wright; H L Uy; Akira Sasaki; Toshiyuki Yoneda; David G Roodman; Gregory R Mundy; B F Boyce
Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(10):1478-87.
1995: Sarah L Dallas; K Miyazono; T M Skerry; Gregory R Mundy; Lynda F Bonewald
Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein.
The Journal of cell biology 1995;131(2):539-49.
1995: Jian Q Feng; Di Chen; J Esparza; Marie A Harris; Gregory R Mundy; Stephen E Harris
Deer antler tissue contains two types of bone morphogenetic protein 4 mRNA transcripts.
Biochimica et biophysica acta 1995;1263(2):163-8.
1995: Akira Sasaki; B F Boyce; Beryl Story; Kenneth Wright; M Chapman; R Boyce; Gregory R Mundy; Toshiyuki Yoneda
Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice.
Cancer research 1995;55(16):3551-7.
1995: Gregory R Mundy; B Boyce; D Hughes; Kenneth Wright; Lynda F Bonewald; Sarah L Dallas; Stephen E Harris; Nandini Ghosh-Choudhury; Di Chen; C Dunstan
The effects of cytokines and growth factors on osteoblastic cells.
Bone 1995;17(2 Suppl):71S-75S.
1995: M Alsina; B F Boyce; Gregory R Mundy; David G Roodman
An in vivo model of human multiple myeloma bone disease.
Stem cells (Dayton, Ohio) 1995;13 Suppl 2():48-50.
1995: H L Uy; Theresa A Guise; J De La Mata; S D Taylor; Beryl Story; Mark Dallas; B F Boyce; Gregory R Mundy; David G Roodman
Effects of parathyroid hormone (PTH)-related protein and PTH on osteoclasts and osteoclast precursors in vivo.
Endocrinology 1995;136(8):3207-12.
1995: J de la Mata; H L Uy; Theresa A Guise; Beryl Story; B F Boyce; Gregory R Mundy; David G Roodman
Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivo.
The Journal of clinical investigation 1995;95(6):2846-52.
1995: G Mbalaviele; H Chen; B F Boyce; Gregory R Mundy; Toshiyuki Yoneda
The role of cadherin in the generation of multinucleated osteoclasts from mononuclear precursors in murine marrow.
The Journal of clinical investigation 1995;95(6):2757-65.
1995: Theresa A Guise; Gregory R Mundy
Clinical review 69: Evaluation of hypocalcemia in children and adults.
The Journal of clinical endocrinology and metabolism 1995;80(5):1473-8.
1995: Toshiyuki Yoneda; P Williams; C Rhine; B F Boyce; C Dunstan; Gregory R Mundy
Suramin suppresses hypercalcemia and osteoclastic bone resorption in nude mice bearing a human squamous cancer.
Cancer research 1995;55(9):1989-93.
1995: Gregory R Mundy
Local control of bone formation by osteoblasts.
Clinical orthopaedics and related research 1995;(313):19-26.
1995: D Chen; Jian Q Feng; M Feng; Marie A Harris; P Mahy; Gregory R Mundy; Stephen E Harris
Sequence and expression of bone morphogenetic protein 3 mRNA in prolonged cultures of fetal rat calvarial osteoblasts and in rat prostate adenocarcinoma PA III cells.
DNA and cell biology 1995;14(3):235-9.
1995: Gregory R Mundy; Toshiyuki Yoneda
Facilitation and suppression of bone metastasis.
Clinical orthopaedics and related research 1995;(312):34-44.
1995: H L Uy; Mark Dallas; J W Calland; B F Boyce; Gregory R Mundy; David G Roodman
Use of an in vivo model to determine the effects of interleukin-1 on cells at different stages in the osteoclast lineage.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(2):295-301.
1994: Gregory R Mundy
Peptides and growth regulatory factors in bone.
Rheumatic diseases clinics of North America 1994;20(3):577-88.
1994: Jian Q Feng; Marie A Harris; Nandini Ghosh-Choudhury; M Feng; Gregory R Mundy; Stephen E Harris
Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes.
Biochimica et biophysica acta 1994;1218(2):221-4.
1994: Gregory R Mundy
Evaluation and treatment of hypercalcemia.
Hospital practice (Office ed.) 1994;29(6):79-84; discussion 84-6.
1994: Stephen E Harris; Lynda F Bonewald; Marie A Harris; M Sabatini; Sarah L Dallas; Jian Q Feng; Nandini Ghosh-Choudhury; John M Wozney; Gregory R Mundy
Effects of transforming growth factor beta on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(6):855-63.
1994: Toshiyuki Yoneda; Y Takaoka; B F Boyce; L Scott; Gregory R Mundy
Extracts of porcine pancreas prevent progression of hypercalcemia and cachexia and prolong survival in nude mice bearing a human squamous carcinoma.
Cancer research 1994;54(9):2509-13.
1994: Stephen E Harris; Marie A Harris; P Mahy; John M Wozney; Jian Q Feng; Gregory R Mundy
Expression of bone morphogenetic protein messenger RNAs by normal rat and human prostate and prostate cancer cells.
The Prostate 1994;24(4):204-11.
1994: Sarah L Dallas; S Park-Snyder; K Miyazono; D Twardzik; Gregory R Mundy; Lynda F Bonewald
Characterization and autoregulation of latent transforming growth factor beta (TGF beta) complexes in osteoblast-like cell lines. Production of a latent complex lacking the latent TGF beta-binding protein.
The Journal of biological chemistry 1994;269(9):6815-21.
1994: Stephen E Harris; M Sabatini; Marie A Harris; Jian Q Feng; John M Wozney; Gregory R Mundy
Expression of bone morphogenetic protein messenger RNA in prolonged cultures of fetal rat calvarial cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(3):389-94.
1994: Nandini Ghosh-Choudhury; Marie A Harris; Jian Q Feng; Gregory R Mundy; Stephen E Harris
Expression of the BMP 2 gene during bone cell differentiation.
Critical reviews in eukaryotic gene expression 1994;4(2-3):345-55.
1994: Elzbieta Izbicka; M Niewolna; Toshiyuki Yoneda; C Lowe; B Boyce; Gregory R Mundy
pp60 c-src expression and activity in MG-63 osteoblastic cells modulated by PTH but not required for PTH-mediated adenylate cyclase response.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(1):127-32.
1993: Gregory R Mundy
Cytokines and growth factors in the regulation of bone remodeling.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8 Suppl 2():S505-10.
1993: Toshiyuki Yoneda; I Kato; L F Bonewald; W H Burgess; Gregory R Mundy
A novel cytokine with osteoclastopoietic activity.
Journal of periodontal research 1993;28(6 Pt 2):521-2.
1993: R O Oreffo; G J Marshall; M Kirchen; C Garcia; W E Gallwitz; J Chavez; Gregory R Mundy; Lynda F Bonewald
Characterization of a cell line derived from a human giant cell tumor that stimulates osteoclastic bone resorption.
Clinical orthopaedics and related research 1993;(296):229-41.
1993: C A Reasner; M D Stone; D J Hosking; A Ballah; Gregory R Mundy
Acute changes in calcium homeostasis during treatment of primary hyperparathyroidism with risedronate.
The Journal of clinical endocrinology and metabolism 1993;77(4):1067-71.
1993: Toshiyuki Yoneda; M Niewolna; C Lowe; Elzbieta Izbicka; Gregory R Mundy
Hormonal regulation of pp60c-src expression during osteoclast formation in vitro.
Molecular endocrinology (Baltimore, Md.) 1993;7(10):1313-8.
1993: Di Chen; Jian Q Feng; M Feng; Marie A Harris; Gregory R Mundy; Stephen E Harris
Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell.
Biochimica et biophysica acta 1993;1174(3):289-92.
1993: Mary H Samuels; J Veldhuis; C Cawley; R J Urban; M Luther; R Bauer; Gregory R Mundy
Pulsatile secretion of parathyroid hormone in normal young subjects: assessment by deconvolution analysis.
The Journal of clinical endocrinology and metabolism 1993;77(2):399-403.
1993: Theresa A Guise; Toshiyuki Yoneda; A J Yates; Gregory R Mundy
The combined effect of tumor-produced parathyroid hormone-related protein and transforming growth factor-alpha enhance hypercalcemia in vivo and bone resorption in vitro.
The Journal of clinical endocrinology and metabolism 1993;77(1):40-5.
1993: Toshiyuki Yoneda; C Lowe; C H Lee; G Gutierrez; M Niewolna; Paul J Williams; Elzbieta Izbicka; Y Uehara; Gregory R Mundy
Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic bone resorption in vitro and hypercalcemia in vivo.
The Journal of clinical investigation 1993;91(6):2791-5.
1993: I Ross Garrett; Theresa A Guise; Lynda F Bonewald; R Chizzonite; Gregory R Mundy
Evidence that interleukin-1 mediates its effects on bone resorption via the 80 kilodalton interleukin-1 receptor.
Calcified tissue international 1993;52(6):438-41.
1993: Gregory R Mundy
Factors which stimulate bone growth in vivo.
Growth regulation 1993;3(2):124-8.
1993: W E Gallwitz; Gregory R Mundy; C H Lee; M Qiao; David G Roodman; M Raftery; S J Gaskell; Lynda F Bonewald
5-Lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts to resorb calcified matrices.
The Journal of biological chemistry 1993;268(14):10087-94.
1993: C Lowe; Toshiyuki Yoneda; B F Boyce; H Chen; Gregory R Mundy; P Soriano
Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4485-9.
1993: Theresa A Guise; I Ross Garrett; Lynda F Bonewald; Gregory R Mundy
Interleukin-1 receptor antagonist inhibits the hypercalcemia mediated by interleukin-1.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(5):583-7.
1993: B F Boyce; H Chen; P Soriano; Gregory R Mundy
Histomorphometric and immunocytochemical studies of src-related osteopetrosis.
Bone 1993;14(3):335-40.
1993: Toshiyuki Yoneda; M Nakai; K Moriyama; L Scott; N Ida; T Kunitomo; Gregory R Mundy
Neutralizing antibodies to human interleukin 6 reverse hypercalcemia associated with a human squamous carcinoma.
Cancer research 1993;53(4):737-40.
1993: Gregory R Mundy
Visions for the future in osteoporosis research.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1993;3 Suppl 2():S29-34.
1993: Gregory R Mundy
Local control of osteoclast function.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1993;3 Suppl 1():126-7.
1992: Theresa A Guise; J M Chirgwin; G Favarato; B F Boyce; Gregory R Mundy
Chinese hamster ovarian cells transfected with human parathyroid hormone-related protein cDNA cause hypercalcemia in nude mice.
Laboratory investigation; a journal of technical methods and pathology 1992;67(4):477-85.
1992: M Nakai; Gregory R Mundy; Paul J Williams; B Boyce; Toshiyuki Yoneda
A synthetic antagonist to laminin inhibits the formation of osteolytic metastases by human melanoma cells in nude mice.
Cancer research 1992;52(19):5395-9.
1992: B F Boyce; Toshiyuki Yoneda; C Lowe; P Soriano; Gregory R Mundy
Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice.
The Journal of clinical investigation 1992;90(4):1622-7.
1992: Michael S Katz; G E Gutierrez; Gregory R Mundy; T K Hymer; M P Caulfield; R L McKee
Tumor necrosis factor and interleukin 1 inhibit parathyroid hormone-responsive adenylate cyclase in clonal osteoblast-like cells by down-regulating parathyroid hormone receptors.
Journal of cellular physiology 1992;153(1):206-13.
1992: A J Yates; B F Boyce; G Favarato; TB Aufdemorte; C Marcelli; M B Kester; R Walker; B C Langton; Lynda F Bonewald; Gregory R Mundy
Expression of human transforming growth factor alpha by Chinese hamster ovarian tumors in nude mice causes hypercalcemia and increased osteoclastic bone resorption.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(7):847-53.
1992: Kaladhar B Reddy; G L Mangold; A K Tandon; Toshiyuki Yoneda; Gregory R Mundy; Asher Zilberstein; C Kent Osborne
Inhibition of breast cancer cell growth in vitro by a tyrosine kinase inhibitor.
Cancer research 1992;52(13):3636-41.
1992: Gregory R Mundy; David G Roodman; Lynda F Bonewald; Toshiyuki Yoneda; M Sabatini
Effects of TNF and lymphotoxin on bone cells.
Immunology series 1992;56():483-98.
1991: Gregory R Mundy
Ectopic production of calciotropic peptides.
Endocrinology and metabolism clinics of North America 1991;20(3):473-87.
1991: Toshiyuki Yoneda; R M Lyall; M M Alsina; P E Persons; A P Spada; A Levitzki; Asher Zilberstein; Gregory R Mundy
The antiproliferative effects of tyrosine kinase inhibitors tyrphostins on a human squamous cell carcinoma in vitro and in nude mice.
Cancer research 1991;51(16):4430-5.
1991: K R Tuttle; R T Kunau; N Loveridge; Gregory R Mundy
Altered renal calcium handling in hypercalcemia of malignancy.
Journal of the American Society of Nephrology : JASN 1991;2(2):191-9.
1991: C A Reasner; Gregory R Mundy
Diagnosis and treatment of osteoporosis.
Comprehensive therapy 1991;17(8):14-9.
1991: Toshiyuki Yoneda; M M Alsina; J L Garcia; Gregory R Mundy
Differentiation of HL-60 cells into cells with the osteoclast phenotype.
Endocrinology 1991;129(2):683-9.
1991: Lynda F Bonewald; L Wakefield; R O Oreffo; A Escobedo; D R Twardzik; Gregory R Mundy
Latent forms of transforming growth factor-beta (TGF beta) derived from bone cultures: identification of a naturally occurring 100-kDa complex with similarity to recombinant latent TGF beta.
Molecular endocrinology (Baltimore, Md.) 1991;5(6):741-51.
1991: A J Yates; R O Oreffo; K Mayor; Gregory R Mundy
Inhibition of bone resorption by inorganic phosphate is mediated by both reduced osteoclast formation and decreased activity of mature osteoclasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6(5):473-8.
1991: K Black; I Ross Garrett; Gregory R Mundy
Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice.
Endocrinology 1991;128(5):2657-9.
1991: Toshiyuki Yoneda; M M Alsina; K Watatani; F Bellot; J Schlessinger; Gregory R Mundy
Dependence of a human squamous carcinoma and associated paraneoplastic syndromes on the epidermal growth factor receptor pathway in nude mice.
Cancer research 1991;51(9):2438-43.
1991: Gregory R Mundy
Inflammatory mediators and the destruction of bone.
Journal of periodontal research 1991;26(3 Pt 2):213-7.
1991: Toshiyuki Yoneda; M A Alsina; J B Chavez; Lynda F Bonewald; R Nishimura; Gregory R Mundy
Evidence that tumor necrosis factor plays a pathogenetic role in the paraneoplastic syndromes of cachexia, hypercalcemia, and leukocytosis in a human tumor in nude mice.
The Journal of clinical investigation 1991;87(3):977-85.
1991: Gregory R Mundy
Is prolonged stimulation of bone growth a therapeutic possibility?
Molecular and cellular endocrinology 1991;75(2):C19-25.
1991: Toshiyuki Yoneda; Y Takaoka; M M Alsina; J Garcia; Gregory R Mundy
Porcine pancreas extract decreases blood-ionized calcium in mice and inhibits osteoclast formation and bone resorption in culture.
FEBS letters 1991;278(2):171-4.
1991: Gregory R Mundy
The effects of TGF-beta on bone.
Ciba Foundation symposium 1991;157():137-43; discussion 143-51.
1991: Gregory R Mundy
Mechanisms of osteolytic bone destruction.
Bone 1991;12 Suppl 1():S1-6.
1991: Gregory R Mundy; David G Roodman; Lynda F Bonewald; R O Oreffo; B F Boyce
Assays for bone resorption and bone formation.
Methods in enzymology 1991;198():502-10.
1990: M Sabatini; A J Yates; I Ross Garrett; J Chavez; J F Dunn; Lynda F Bonewald; Gregory R Mundy
Increased production of tumor necrosis factor by normal immune cells in a model of the humoral hypercalcemia of malignancy.
Laboratory investigation; a journal of technical methods and pathology 1990;63(5):676-82.
1990: C Marcelli; A J Yates; Gregory R Mundy
In vivo effects of human recombinant transforming growth factor beta on bone turnover in normal mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(10):1087-96.
1990: G E Gutierrez; Gregory R Mundy; D R Manning; E L Hewlett; Michael S Katz
Transforming growth factor beta enhances parathyroid hormone stimulation of adenylate cyclase in clonal osteoblast-like cells.
Journal of cellular physiology 1990;144(3):438-47.
1990: A J Yates; G E Gutierrez; I Ross Garrett; J J Mencel; G W Nuss; A B Schreiber; Gregory R Mundy
A noncyclical analog of salmon calcitonin (N alpha-propionyl Di-Ala1,7,des-Leu19 sCT) retains full potency without inducing anorexia in rats.
Endocrinology 1990;126(6):2845-9.
1990: R O Oreffo; Lynda F Bonewald; A Kukita; I Ross Garrett; S M Seyedin; D Rosen; Gregory R Mundy
Inhibitory effects of the bone-derived growth factors osteoinductive factor and transforming growth factor-beta on isolated osteoclasts.
Endocrinology 1990;126(6):3069-75.
1990: M Sabatini; J Chavez; Gregory R Mundy; Lynda F Bonewald
Stimulation of tumor necrosis factor release from monocytic cells by the A375 human melanoma via granulocyte-macrophage colony-stimulating factor.
Cancer research 1990;50(9):2673-8.
1990: A Kukita; L Bonewald; D Rosen; S Seyedin; Gregory R Mundy; David G Roodman
Osteoinductive factor inhibits formation of human osteoclast-like cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(8):3023-6.
1990: Gregory R Mundy
Pathophysiology of cancer-associated hypercalcemia.
Seminars in oncology 1990;17(2 Suppl 5):10-5.
1990: I Ross Garrett; B F Boyce; R O Oreffo; Lynda F Bonewald; James W Poser; Gregory R Mundy
Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo.
The Journal of clinical investigation 1990;85(3):632-9.
1990: G E Gutierrez; James W Poser; Michael S Katz; A J Yates; H L Henry; Gregory R Mundy
Mechanisms of hypercalcaemia of malignancy.
Baillière's clinical endocrinology and metabolism 1990;4(1):119-38.
1990: C A Reasner; A J Yates; Gregory R Mundy
Parathyroid gland disease and hypercalcemia.
Current opinion in rheumatology 1990;2(1):20-5.
1990: Lynda F Bonewald; Gregory R Mundy
Role of transforming growth factor-beta in bone remodeling.
Clinical orthopaedics and related research 1990;(250):261-76.
1990: J Pfeilschifter; Lynda F Bonewald; Gregory R Mundy
Characterization of the latent transforming growth factor beta complex in bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(1):49-58.
1990: C A Reasner; J F Dunn; D A Fetchick; Y Liel; Bruce W Hollis; Solomon Epstein; J Shary; Gregory R Mundy; Norman H Bell
Alteration of vitamin D metabolism in Mexican-Americans.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(1):13-7.
1990: Gregory R Mundy; Lynda F Bonewald
Role of TGF beta in bone remodeling.
Annals of the New York Academy of Sciences 1990;593():91-7.
1989: B F Boyce; A J Yates; Gregory R Mundy
Bolus injections of recombinant human interleukin-1 cause transient hypocalcemia in normal mice.
Endocrinology 1989;125(5):2780-3.
1989: I Ross Garrett; Gregory R Mundy
Relationship between interleukin-1 and prostaglandins in resorbing neonatal calvaria.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1989;4(5):789-94.
1989: B F Boyce; T B Aufdemorte; I Ross Garrett; A J Yates; Gregory R Mundy
Effects of interleukin-1 on bone turnover in normal mice.
Endocrinology 1989;125(3):1142-50.
1989: Gregory R Mundy
Hypercalcemic factors other than parathyroid hormone-related protein.
Endocrinology and metabolism clinics of North America 1989;18(3):795-806.
1989: Gregory R Mundy; A J Yates
Recent advances in pathophysiology and treatment of hypercalcemia of malignancy.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1989;14(1):2-12.
1989: R O Oreffo; Gregory R Mundy; S M Seyedin; Lynda F Bonewald
Activation of the bone-derived latent TGF beta complex by isolated osteoclasts.
Biochemical and biophysical research communications 1989;158(3):817-23.
1989: J Pfeilschifter; C Chenu; A Bird; Gregory R Mundy; David G Roodman
Interleukin-1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1989;4(1):113-8.
1989: Lynda F Bonewald; Gregory R Mundy
Role of transforming growth factor beta in bone remodeling: a review.
Connective tissue research 1989;23(2-3):201-8.
1988: J Pfeilschifter; S M Seyedin; Gregory R Mundy
Transforming growth factor beta inhibits bone resorption in fetal rat long bone cultures.
The Journal of clinical investigation 1988;82(2):680-5.
1988: C Chenu; J Pfeilschifter; Gregory R Mundy; David G Roodman
Transforming growth factor beta inhibits formation of osteoclast-like cells in long-term human marrow cultures.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(15):5683-7.
1988: Gregory R Mundy
Hypercalcemia of malignancy revisited.
The Journal of clinical investigation 1988;82(1):1-6.
1988: M Sabatini; B Boyce; T Aufdemorte; Lynda F Bonewald; Gregory R Mundy
Infusions of recombinant human interleukins 1 alpha and 1 beta cause hypercalcemia in normal mice.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(14):5235-9.
1988: A J Yates; G E Gutierrez; P Smolens; P S Travis; Michael S Katz; TB Aufdemorte; B F Boyce; T K Hymer; James W Poser; Gregory R Mundy
Effects of a synthetic peptide of a parathyroid hormone-related protein on calcium homeostasis, renal tubular calcium reabsorption, and bone metabolism in vivo and in vitro in rodents.
The Journal of clinical investigation 1988;81(3):932-8.
1987: G E Gutierrez; Gregory R Mundy; R Derynck; E L Hewlett; Michael S Katz
Inhibition of parathyroid hormone-responsive adenylate cyclase in clonal osteoblast-like cells by transforming growth factor alpha and epidermal growth factor.
The Journal of biological chemistry 1987;262(33):15845-50.
1987: I Ross Garrett; B G Durie; G E Nedwin; A Gillespie; T Bringman; M Sabatini; D R Bertolini; Gregory R Mundy
Production of lymphotoxin, a bone-resorbing cytokine, by cultured human myeloma cells.
The New England journal of medicine 1987;317(9):526-32.
1987: Gregory R Mundy
Bone resorption and turnover in health and disease.
Bone 1987;8 Suppl 1():S9-16.
1986: M Gowen; G E Nedwin; Gregory R Mundy
Preferential inhibition of cytokine-stimulated bone resorption by recombinant interferon gamma.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1986;1(5):469-74.
1986: G E Gutierrez; Gregory R Mundy; Michael S Katz
Alterations in hormone-sensitive adenylate cyclase of cloned rat osteosarcoma cells during long-term culture.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1986;1(4):319-26.
1986: D R Bertolini; G E Nedwin; T S Bringman; D D Smith; Gregory R Mundy
Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors.
Nature 1986;319(6053):516-8.