FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Robert Munford

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Phenomena

Acylation

Concepts & Ideas

Procedures

Disorders

Co-author Network

Publications

TOP 3
Baomei Shao; Richard L Kitchens; Robert S Munford; Alan W Varley
Hepatic uptake and deacylation of the LPS in bloodborne LPS-lipoprotein complexes.
Noredia Ojogun; Tang-Yong Kuang; Baomei Shao; David Greaves; Robert S Munford; Alan W Varley
Overproduction of acyloxyacyl hydrolase by macrophages and dendritic cells prevents prolonged reactions to bacterial lipopolysaccharide in vivo.
Mingfang Lu; Alan W Varley; Shoichiro Ohta; John Hardwick; Robert S Munford
Host inactivation of bacterial lipopolysaccharide prevents prolonged tolerance following gram-negative bacterial infection.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Robert Munford (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Baomei Shao; Richard L Kitchens; Robert S Munford; Alan W Varley
Hepatic uptake and deacylation of the LPS in bloodborne LPS-lipoprotein complexes.
Innate immunity 2012;18(6):825-33.
2009: Noredia Ojogun; Tang-Yong Kuang; Baomei Shao; David Greaves; Robert S Munford; Alan W Varley
Overproduction of acyloxyacyl hydrolase by macrophages and dendritic cells prevents prolonged reactions to bacterial lipopolysaccharide in vivo.
The Journal of infectious diseases 2009;200(11):1685-93.
2008: Mingfang Lu; Alan W Varley; Shoichiro Ohta; John Hardwick; Robert S Munford
Host inactivation of bacterial lipopolysaccharide prevents prolonged tolerance following gram-negative bacterial infection.
Cell host & microbe 2008;4(3):293-302.
2008: Robert S Munford
Sensing gram-negative bacterial lipopolysaccharides: a human disease determinant?
Infection and immunity 2008;76(2):454-65.
2007: Baomei Shao; Mingfang Lu; Steven C Katz; Alan W Varley; John Hardwick; Thomas E Rogers; Noredia Ojogun; Donald C Rockey; Ronald P DeMatteo; Robert S Munford
A host lipase detoxifies bacterial lipopolysaccharides in the liver and spleen.
The Journal of biological chemistry 2007;282(18):13726-35.
2007: Theresa L Gioannini; Athmane Teghanemt; DeSheng Zhang; Polonca Prohinar; Erika N Levis; Robert S Munford; Jerrold P Weiss
Endotoxin-binding proteins modulate the susceptibility of bacterial endotoxin to deacylation by acyloxyacyl hydrolase.
The Journal of biological chemistry 2007;282(11):7877-84.
2007: Jean-Marc Cavaillon; Robert S Munford
A tribute to Ernst Th. Rietschel: the gentleman scientist.
Journal of endotoxin research 2007;13(1):3-5.
2006: Robert S Munford; Alan W Varley
Shield as signal: lipopolysaccharides and the evolution of immunity to gram-negative bacteria.
PLoS pathogens 2006;2(6):e67.
2006: Robert S Munford
Severe sepsis and septic shock: the role of gram-negative bacteremia.
Annual review of pathology 2006;1():467-96.
2005: Mingfang Lu; Mei Zhang; Akira Takashima; Jerrold Weiss; Michael A Apicella; Xiang-Hong Li; Dorothy Yuan; Robert S Munford
Lipopolysaccharide deacylation by an endogenous lipase controls innate antibody responses to Gram-negative bacteria.
Nature immunology 2005;6(10):989-94.
2005: James P Luby; Paul M Southern; Charles E Haley; Kirby L Vahle; Robert S Munford; Robert W Haley
Recurrent exposure to Histoplasma capsulatum in modern air-conditioned buildings.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;41(2):170-6.
2005: Robert S Munford
Detoxifying endotoxin: time, place and person.
Journal of endotoxin research 2005;11(2):69-84.
2004: Fernando A Rivera-Chavez; Dixie L Peters-Hybki; Robert C Barber; Guy Lindberg; Ishwarlal Jialal; Robert S Munford; Grant E O'Keefe
Innate immunity genes influence the severity of acute appendicitis.
Annals of surgery 2004;240(2):269-77.
2004: J Amelia Feulner; Mingfang Lu; John M Shelton; Mei Zhang; James A Richardson; Robert S Munford
Identification of acyloxyacyl hydrolase, a lipopolysaccharide-detoxifying enzyme, in the murine urinary tract.
Infection and immunity 2004;72(6):3171-8.
2003: Richard L Kitchens; Patricia A Thompson; Robert S Munford; Grant E O'Keefe
Acute inflammation and infection maintain circulating phospholipid levels and enhance lipopolysaccharide binding to plasma lipoproteins.
Journal of lipid research 2003;44(12):2339-48.
2003: Mingfang Lu; Mei Zhang; Richard L Kitchens; Susan P Fosmire; Akira Takashima; Robert S Munford
Stimulus-dependent deacylation of bacterial lipopolysaccharide by dendritic cells.
The Journal of experimental medicine 2003;197(12):1745-54.
2003: Fernando A Rivera-Chavez; Herbert Wheeler; Guy Lindberg; Robert S Munford; Grant E O'Keefe
Regional and systemic cytokine responses to acute inflammation of the vermiform appendix.
Annals of surgery 2003;237(3):408-16.
2002: H Shaw Warren; Anthony F Suffredini; Peter Q Eichacker; Robert S Munford
Risks and benefits of activated protein C treatment for severe sepsis.
The New England journal of medicine 2002;347(13):1027-30.
2002: Robert S Munford; Kevin Tracey
Is severe sepsis a neuroendocrine disease?
Molecular medicine (Cambridge, Mass.) 2002;8(8):437-42.
2002: Andrew C Bakker; Fons A J van de Loo; Leo A B Joosten; Onno J Arntz; Alan W Varley; Robert S Munford; Wim B van den Berg
C3-Tat/HIV-regulated intraarticular human interleukin-1 receptor antagonist gene therapy results in efficient inhibition of collagen-induced arthritis superior to cytomegalovirus-regulated expression of the same transgene.
Arthritis and rheumatism 2002;46(6):1661-70.
2002: Alexei Miagkov; Alan W Varley; Robert S Munford; Sergei S Makarov
Endogenous regulation of a therapeutic transgene restores homeostasis in arthritic joints.
The Journal of clinical investigation 2002;109(9):1223-9.
2002: Grant E O'Keefe; Dixie L Hybki; Robert S Munford
The G-->A single nucleotide polymorphism at the -308 position in the tumor necrosis factor-alpha promoter increases the risk for severe sepsis after trauma.
The Journal of trauma 2002;52(5):817-25; discussion 825-6.
2001: Richard L Kitchens; Patricia A Thompson; Suganya Viriyakosol; Grant E O'Keefe; Robert S Munford
Plasma CD14 decreases monocyte responses to LPS by transferring cell-bound LPS to plasma lipoproteins.
The Journal of clinical investigation 2001;108(3):485-93.
2001: M Rygg; CM Uhlar; Caroline Thorn; Liselotte E Jensen; DJ Gaughan; Alan W Varley; Robert S Munford; Rüdiger Göke; Y Chen; Alexander S Whitehead
In vitro evaluation of an enhanced human serum amyloid A (SAA2) promoter-regulated soluble TNF receptor fusion protein for anti-inflammatory gene therapy.
Scandinavian journal of immunology 2001;53(6):588-95.
2001: J Cowan; Christopher M Sinton; Alan W Varley; Frank H Wians; Robert W Haley; Robert S Munford
Gene therapy to prevent organophosphate intoxication.
Toxicology and applied pharmacology 2001;173(1):1-6.
2001: Robert S Munford; Jérôme Pugin
Normal responses to injury prevent systemic inflammation and can be immunosuppressive.
American journal of respiratory and critical care medicine 2001;163(2):316-21.
2001: Robert S Munford; Jérôme Pugin
The crucial role of systemic responses in the innate (non-adaptive) host defense.
Journal of endotoxin research 2001;7(4):327-32.
2000: C J Vesy; Richard L Kitchens; Gertrud Wolfbauer; John J Albers; Robert S Munford
Lipopolysaccharide-binding protein and phospholipid transfer protein release lipopolysaccharides from gram-negative bacterial membranes.
Infection and immunity 2000;68(5):2410-7.
2000: Richard L Kitchens; Patricia A Thompson; Grant E O'Keefe; Robert S Munford
Plasma constituents regulate LPS binding to, and release from, the monocyte cell surface.
Journal of endotoxin research 2000;6(6):477-82.
1999: Richard L Kitchens; Gertrud Wolfbauer; John J Albers; Robert S Munford
Plasma lipoproteins promote the release of bacterial lipopolysaccharide from the monocyte cell surface.
The Journal of biological chemistry 1999;274(48):34116-22.
1999: P Y Wang; Robert S Munford
CD14-dependent internalization and metabolism of extracellular phosphatidylinositol by monocytes.
The Journal of biological chemistry 1999;274(33):23235-41.
1999: C R Gregg; Thomas E Rogers; Robert S Munford
Xanthogranulomatous pyelonephritis.
Current clinical topics in infectious diseases 1999;19():287-304.
1998: Richard L Kitchens; P Wang; Robert S Munford
Bacterial lipopolysaccharide can enter monocytes via two CD14-dependent pathways.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(10):5534-45.
1998: Alan W Varley; Robert S Munford
Physiologically responsive gene therapy.
Molecular medicine today 1998;4(10):445-51.
1998: P Y Wang; Richard L Kitchens; Robert S Munford
Phosphatidylinositides bind to plasma membrane CD14 and can prevent monocyte activation by bacterial lipopolysaccharide.
The Journal of biological chemistry 1998;273(38):24309-13.
1998: Richard L Kitchens; Robert S Munford
CD14-dependent internalization of bacterial lipopolysaccharide (LPS) is strongly influenced by LPS aggregation but not by cellular responses to LPS.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(4):1920-8.
1997: Alan W Varley; S M Geiszler; R B Gaynor; Robert S Munford
A two-component expression system that responds to inflammatory stimuli in vivo.
Nature biotechnology 1997;15(10):1002-6.
1996: M G Coulthard; J Swindle; Robert S Munford; Robert D Gerard; Robert S Meidell
Adenovirus-mediated transfer of a gene encoding acyloxyacyl hydrolase (AOAH) into mice increases tissue and plasma AOAH activity.
Infection and immunity 1996;64(5):1510-5.
1995: Robert S Munford; P O Sheppard; P J O'Hara
Saposin-like proteins (SAPLIP) carry out diverse functions on a common backbone structure.
Journal of lipid research 1995;36(8):1653-63.
1995: Alan W Varley; M G Coulthard; Robert S Meidell; Robert D Gerard; Robert S Munford
Inflammation-induced recombinant protein expression in vivo using promoters from acute-phase protein genes.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5346-50.
1995: Richard L Kitchens; Robert S Munford
Enzymatically deacylated lipopolysaccharide (LPS) can antagonize LPS at multiple sites in the LPS recognition pathway.
The Journal of biological chemistry 1995;270(17):9904-10.
1995: P Y Wang; Richard L Kitchens; Robert S Munford
Bacterial lipopolysaccharide binds to CD14 in low-density domains of the monocyte-macrophage plasma membrane.
Journal of inflammation 1995;47(3):126-37.
1995: Richard L Kitchens; Robert S Munford
Modulation of protein tyrosine phosphorylation in human cells by LPS and enzymatically deacylated LPS.
Progress in clinical and biological research 1995;392():353-63.
1994: Janet F. Staab; D L Ginkel; G B Rosenberg; Robert S Munford
A saposin-like domain influences the intracellular localization, stability, and catalytic activity of human acyloxyacyl hydrolase.
The Journal of biological chemistry 1994;269(38):23736-42.
1993: M Luchi; Robert S Munford
Binding, internalization, and deacylation of bacterial lipopolysaccharide by human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(2):959-69.
1992: Richard L Kitchens; R J Ulevitch; Robert S Munford
Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway.
The Journal of experimental medicine 1992;176(2):485-94.
1992: Robert S Munford; J P Hunter
Acyloxyacyl hydrolase, a leukocyte enzyme that deacylates bacterial lipopolysaccharides, has phospholipase, lysophospholipase, diacylglycerollipase, and acyltransferase activities in vitro.
The Journal of biological chemistry 1992;267(14):10116-21.
1992: Robert S Munford; L C DeVeaux; John E Cronan; P D Rick
Biosynthetic radiolabeling of bacterial lipopolysaccharide to high specific activity.
Journal of immunological methods 1992;148(1-2):115-20.
1992: Robert S Munford; Alice L Erwin
Eukaryotic lipopolysaccharide deacylating enzyme.
Methods in enzymology 1992;209():485-92.
1991: Alice L Erwin; Robert S Munford
Plasma lipopolysaccharide-deacylating activity (acyloxyacyl hydrolase) increases after lipopolysaccharide administration to rabbits.
Laboratory investigation; a journal of technical methods and pathology 1991;65(2):138-44.
1991: J Mertsola; Leslie D Cope; Robert S Munford; George H McCracken; E J Hansen
Detection of experimental Haemophilus influenzae type b bacteremia and endotoxemia by means of an immunolimulus assay.
The Journal of infectious diseases 1991;164(2):353-8.
1991: Alice L Erwin; Robert Mandrell; Robert S Munford
Enzymatically deacylated Neisseria lipopolysaccharide (LPS) inhibits murine splenocyte mitogenesis induced by LPS.
Infection and immunity 1991;59(6):1881-7.
1990: J Mertsola; Robert S Munford; Octavio Ramilo; Xavier Sáez-Llorens; Mahmoud M Mustafa; George H McCracken; E J Hansen
Specific detection of Haemophilus influenzae type b lipooligosaccharide by immunoassay.
Journal of clinical microbiology 1990;28(12):2700-6.
1990: Alice L Erwin; Robert S Munford
Deacylation of structurally diverse lipopolysaccharides by human acyloxyacyl hydrolase.
The Journal of biological chemistry 1990;265(27):16444-9.
1990: F X Riedo; Robert S Munford; W B Campbell; J S Reisch; K R Chien; Robert D Gerard
Deacylated lipopolysaccharide inhibits plasminogen activator inhibitor-1, prostacyclin, and prostaglandin E2 induction by lipopolysaccharide but not by tumor necrosis factor-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3506-12.
1989: Robert S Munford; C L Hall
Purification of acyloxyacyl hydrolase, a leukocyte enzyme that removes secondary acyl chains from bacterial lipopolysaccharides.
The Journal of biological chemistry 1989;264(26):15613-9.
1989: Alice L Erwin; Robert S Munford
Comparison of lipopolysaccharides from Brazilian purpuric fever isolates and conjunctivitis isolates of Haemophilus influenzae biogroup aegyptius. Brazilian Purpuric Fever Study Group.
Journal of clinical microbiology 1989;27(4):762-7.
1988: G A Syrogiannopoulos; E J Hansen; Alice L Erwin; Robert S Munford; J Rutledge; J S Reisch; George H McCracken
Haemophilus influenzae type b lipooligosaccharide induces meningeal inflammation.
The Journal of infectious diseases 1988;157(2):237-44.
1987: Robert S Munford; C L Hall
A comparison of two quantitative assays for bacterial lipopolysaccharides.
Progress in clinical and biological research 1987;231():93-102.
1986: Robert S Munford; C L Hall
Detoxification of bacterial lipopolysaccharides (endotoxins) by a human neutrophil enzyme.
Science (New York, N.Y.) 1986;234(4773):203-5.
1985: Robert S Munford; C L Hall
Uptake and deacylation of bacterial lipopolysaccharides by macrophages from normal and endotoxin-hyporesponsive mice.
Infection and immunity 1985;48(2):464-73.
1984: Robert S Munford; C L Hall; L Grimm
Detection of free endotoxin in cerebrospinal fluid by the Limulus lysate test.
Infection and immunity 1984;45(2):531-3.
1983: C L Hall; Robert S Munford
Enzymatic deacylation of the lipid A moiety of Salmonella typhimurium lipopolysaccharides by human neutrophils.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(21):6671-5.
1982: Robert S Munford; C L Hall; J M Lipton; J M Dietschy
Biological activity, lipoprotein-binding behavior, and in vivo disposition of extracted and native forms of Salmonella typhimurium lipopolysaccharides.
The Journal of clinical investigation 1982;70(4):877-88.
1981: Robert S Munford; C L Hall; J M Dietschy
Binding of Salmonella typhimurium lipopolysaccharides to rat high-density lipoproteins.
Infection and immunity 1981;34(3):835-43.
1980: Robert S Munford; C L Hall; P D Rick
Size heterogeneity of Salmonella typhimurium lipopolysaccharides in outer membranes and culture supernatant membrane fragments.
Journal of bacteriology 1980;144(2):630-40.