Ferid Murad

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Murad Ferid; Barber Roger
A hypothesis about cellular signaling with nitric oxide in the earliest life forms in evolution.
Tanifum Eric A; Kots Alexander Y; Choi Byung-Kwon; Murad Ferid; Gilbertson Scott R
Novel pyridopyrimidine derivatives as inhibitors of stable toxin a (STa) induced cGMP synthesis.
Inaba Hiroaki; Hokamura Kazuya; Nakano Kazuhiko; Nomura Ryota; Katayama Kazufumi; Nakajima Atsushi; Yoshioka Hideo; Taniguchi Kazuhiro; Kamisaki Yoshinori; Ooshima Takashi; Umemura Kazuo; Murad Ferid; Wada Koichiro; Amano Atsuo
Upregulation of S100 calcium-binding protein A9 is required for induction of smooth muscle cell proliferation by a periodontal pathogen.

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All Publications

2009: Murad Ferid; Barber Roger
A hypothesis about cellular signaling with nitric oxide in the earliest life forms in evolution.
Free radical biology & medicine 2009;47(9):1325-7.
2009: Tanifum Eric A; Kots Alexander Y; Choi Byung-Kwon; Murad Ferid; Gilbertson Scott R
Novel pyridopyrimidine derivatives as inhibitors of stable toxin a (STa) induced cGMP synthesis.
Bioorganic & medicinal chemistry letters 2009;19(11):3067-71.
2009: Inaba Hiroaki; Hokamura Kazuya; Nakano Kazuhiko; Nomura Ryota; Katayama Kazufumi; Nakajima Atsushi; Yoshioka Hideo; Taniguchi Kazuhiro; Kamisaki Yoshinori; Ooshima Takashi; Umemura Kazuo; Murad Ferid; Wada Koichiro; Amano Atsuo
Upregulation of S100 calcium-binding protein A9 is required for induction of smooth muscle cell proliferation by a periodontal pathogen.
FEBS letters 2009;583(1):128-34.
2009: Bryan Nathan S; Bian Ka; Murad Ferid
Discovery of the nitric oxide signaling pathway and targets for drug development.
Frontiers in bioscience : a journal and virtual library 2009;14():1-18.
2008: Mujoo Kalpana; Sharin Vladislav G; Bryan Nathan S; Krumenacker Joshua S; Sloan Courtney; Parveen Shanaz; Nikonoff Lubov E; Kots Alexander Y; Murad Ferid
Role of nitric oxide signaling components in differentiation of embryonic stem cells into myocardial cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(48):18924-9.
2008: Zhu Haifeng; Wei Xiaofei; Bian Ka; Murad Ferid
Effects of nitric oxide on skin burn wound healing.
Journal of burn care & research : official publication of the American Burn Association 2008;29(5):804-14.
2008: Kots Alexander Y; Choi Byung-Kwon; Estrella-Jimenez Maria E; Warren Cirle A; Gilbertson Scott R; Guerrant Richard L; Murad Ferid
Pyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: Application for treatment of diarrhea.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(24):8440-5.
2008: Murad Ferid
Nitric oxide and cyclic guanosine monophosphate signaling in the eye.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 2008;43(3):291-4.
2008: Sharina Iraida G; Jelen Filip; Bogatenkova Elena P; Thomas Anthony; Martin Emil; Murad Ferid
Alpha1 soluble guanylyl cyclase (sGC) splice forms as potential regulators of human sGC activity.
The Journal of biological chemistry 2008;283(22):15104-13.
2008: Bian Ka; Doursout Marie-Françoise; Murad Ferid
Vascular system: role of nitric oxide in cardiovascular diseases.
Journal of clinical hypertension (Greenwich, Conn.) 2008;10(4):304-10.
2007: Rayala Suresh K; Martin Emil; Sharina Iraida G; Molli Poonam R; Wang Xiaoping; Jacobson Raymond; Murad Ferid; Kumar Rakesh
Dynamic interplay between nitration and phosphorylation of tubulin cofactor B in the control of microtubule dynamics.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19470-5.
2007: Seminara Aurora R; Ruvolo Peter P; Murad Ferid
LPS/IFNgamma-induced RAW 264.7 apoptosis is regulated by both nitric oxide-dependent and -independent pathways involving JNK and the Bcl-2 family.
Cell cycle (Georgetown, Tex.) 2007;6(14):1772-8.
2007: Zhu Haifeng; Ka Bian; Murad Ferid
Nitric oxide accelerates the recovery from burn wounds.
World journal of surgery 2007;31(4):624-31.
2007: Madhusoodanan K S; Murad Ferid
NO-cGMP signaling and regenerative medicine involving stem cells.
Neurochemical research 2007;32(4-5):681-94.
2006: Mujoo Kalpana; Krumenacker Joshua S; Wada Yoshiko; Murad Ferid
Differential expression of nitric oxide signaling components in undifferentiated and differentiated human embryonic stem cells.
Stem cells and development 2006;15(6):779-87.
2006: Murad Ferid
Shattuck Lecture. Nitric oxide and cyclic GMP in cell signaling and drug development.
The New England journal of medicine 2006;355(19):2003-11.
2006: Martin Emil; Berka Vladimir; Bogatenkova Elena; Murad Ferid; Tsai Ah-Lim
Ligand selectivity of soluble guanylyl cyclase: effect of the hydrogen-bonding tyrosine in the distal heme pocket on binding of oxygen, nitric oxide, and carbon monoxide.
The Journal of biological chemistry 2006;281(38):27836-45.
2006: Bian Ka; Ke Yan; Kamisaki Yoshinori; Murad Ferid
Proteomic modification by nitric oxide.
Journal of pharmacological sciences 2006;101(4):271-9.
2006: Krumenacker Joshua S; Murad Ferid
NO-cGMP signaling in development and stem cells.
Molecular genetics and metabolism 2006;87(4):311-4.
2006: Thompson Linda; Turko Illarion; Murad Ferid
Mass spectrometry-based relative quantification of human neutrophil peptides 1, 2, and 3 from biological samples.
Molecular immunology 2006;43(9):1485-9.
2006: Marcondes Sisi; Cardoso Marcia H M; Morganti Rafael P; Thomazzi Sara M; Lilla Sergio; Murad Ferid; De Nucci Gilberto; Antunes Edson
Cyclic GMP-independent mechanisms contribute to the inhibition of platelet adhesion by nitric oxide donor: a role for alpha-actinin nitration.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3434-9.
2006: Göçmen Cemil; Büyüknacar H Sinem; Kots Alexander Ya; Murad Ferid; Kiroglu Olcay; Kumcu Eda Karabal
The relaxant activity of 4,7-dimethyl-1,2,5-oxadiazolo[3,4-d]-pyridazine 1,5,6-trioxide in the mouse corpus cavernosum.
The Journal of pharmacology and experimental therapeutics 2006;316(2):753-61.
2006: Krumenacker Joshua S; Katsuki Shoji; Kots Alexander; Murad Ferid
Differential expression of genes involved in cGMP-dependent nitric oxide signaling in murine embryonic stem (ES) cells and ES cell-derived cardiomyocytes.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;14(1):1-11.
2006: Bhuiyan Md Badiul; Murad Ferid; Fant Michael E
The placental cholinergic system: localization to the cytotrophoblast and modulation of nitric oxide.
Cell communication and signaling : CCS 2006;4():4.
2005: Krumenacker Joshua S; Kots Alexander; Murad Ferid
Effects of the JNK inhibitor anthra[1,9-cd]pyrazol-6(2H)-one (SP-600125) on soluble guanylyl cyclase alpha1 gene regulation and cGMP synthesis.
American journal of physiology. Cell physiology 2005;289(4):C778-84.
2005: Martin Emil; Czarnecki Kazimierz; Jayaraman Vasanthi; Murad Ferid; Kincaid James
Resonance Raman and infrared spectroscopic studies of high-output forms of human soluble guanylyl cyclase.
Journal of the American Chemical Society 2005;127(13):4625-31.
2005: Bian Ka; Zhong Meng; Harari Yael; Lai Mildred; Weisbrodt Norman; Murad Ferid
Helminth regulation of host IL-4Ralpha/Stat6 signaling: mechanism underlying NOS-2 inhibition by Trichinella spiralis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):3936-41.
2005: Deng Weimin; Han Qin; Liao Lianming; Li Changhong; Ge Wei; Zhao Zhigang; You Shengguo; Deng Hongye; Murad Ferid; Zhao Robert C H
Engrafted bone marrow-derived flk-(1+) mesenchymal stem cells regenerate skin tissue.
Tissue engineering 2005;11(1-2):110-9.
2005: Murad Ferid
Some highlights of a 47 year career in research.
Cellular and molecular life sciences : CMLS 2005;62(1):1-3.
2005: Martin Emil; Berka Vladimir; Tsai Ah-Lim; Murad Ferid
Soluble guanylyl cyclase: the nitric oxide receptor.
Methods in enzymology 2005;396():478-92.
2005: Turko Illarion V; Murad Ferid
Mapping sites of tyrosine nitration by matrix-assisted laser desorption/ionization mass spectrometry.
Methods in enzymology 2005;396():266-75.
2004: Hanafy Khalid A; Martin Emil; Murad Ferid
CCTeta, a novel soluble guanylyl cyclase-interacting protein.
The Journal of biological chemistry 2004;279(45):46946-53.
2004: Murad Ferid
Discovery of some of the biological effects of nitric oxide and its role in cell signaling.
Bioscience reports 2004;24(4-5):452-74.
2004: Murad Ferid
Ferid Murad, MD, PhD: a conversation with the editor.
The American journal of cardiology 2004;94(1):75-91.
2004: Krumenacker Joshua S; Hanafy Khalid A; Murad Ferid
Regulation of nitric oxide and soluble guanylyl cyclase.
Brain research bulletin 2004;62(6):505-15.
2004: Ruiz-Stewart I; Tiyyagura S R; Lin J E; Kazerounian S; Pitari G M; Schulz S; Martin E; Murad F; Waldman S A
Guanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):37-42.
2003: Jurasz Paul; Alonso David; Castro-Blanco Susana; Murad Ferid; Radomski Marek W
Generation and role of angiostatin in human platelets.
Blood 2003;102(9):3217-23.
2003: Sharina Iraida G; Martin Emil; Thomas Anthony; Uray Karen L; Murad Ferid
CCAAT-binding factor regulates expression of the beta1 subunit of soluble guanylyl cyclase gene in the BE2 human neuroblastoma cell line.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11523-8.
2003: Turko Illarion V; Murad Ferid
Quantitative protein profiling in heart mitochondria from diabetic rats.
The Journal of biological chemistry 2003;278(37):35844-9.
2003: Turko Illarion V; Li Li; Aulak Kulwant S; Stuehr Dennis J; Chang Jui-Yoa; Murad Ferid
Protein tyrosine nitration in the mitochondria from diabetic mouse heart. Implications to dysfunctional mitochondria in diabetes.
The Journal of biological chemistry 2003;278(36):33972-7.
2003: Martin Emil; Sharina Iraida; Kots Alexander; Murad Ferid
A constitutively activated mutant of human soluble guanylyl cyclase (sGC): implication for the mechanism of sGC activation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9208-13.
2003: Irie Yasuyuki; Saeki Makio; Kamisaki Yoshinori; Martin Emil; Murad Ferid
Histone H1.2 is a substrate for denitrase, an activity that reduces nitrotyrosine immunoreactivity in proteins.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5634-9.
2003: Bian Ka; Gao Zhonghong; Weisbrodt Norman; Murad Ferid
The nature of heme/iron-induced protein tyrosine nitration.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5712-7.
2003: Murad Ferid
The excitement and rewards of research with our discovery of some of the biological effects of nitric oxide.
Circulation research 2003;92(4):339-41.
2003: Adewuya Oladapo; Irie Yasuyuki; Bian Ka; Onigu-Otite Edore; Murad Ferid
Mechanism of vasculitis and aneurysms in Kawasaki disease: role of nitric oxide.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2003;8(1):15-25.
2003: Bian Ka; Murad Ferid
Nitric oxide (NO)--biogeneration, regulation, and relevance to human diseases.
Frontiers in bioscience : a journal and virtual library 2003;8():d264-78.
2002: Turko Illarion V; Murad Ferid
Protein nitration in cardiovascular diseases.
Pharmacological reviews 2002;54(4):619-34.
2001: Turko I V; Marcondes S; Murad F
Diabetes-associated nitration of tyrosine and inactivation of succinyl-CoA:3-oxoacid CoA-transferase.
American journal of physiology. Heart and circulatory physiology 2001;281(6):H2289-94.
2001: Martin E; Lee Y C; Murad F
YC-1 activation of human soluble guanylyl cyclase has both heme-dependent and heme-independent components.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):12938-42.
2001: Bian K; Murad F
Diversity of endotoxin-induced nitrotyrosine formation in macrophage-endothelium-rich organs.
Free radical biology & medicine 2001;31(4):421-9.
2001: Mendes R V; Martins A R; de Nucci G; Murad F; Soares F A
Expression of nitric oxide synthase isoforms and nitrotyrosine immunoreactivity by B-cell non-Hodgkin's lymphomas and multiple myeloma.
Histopathology 2001;39(2):172-8.
2001: Ishii N; Patel K P; Lane P H; Taylor T; Bian K; Murad F; Pollock J S; Carmines P K
Nitric oxide synthesis and oxidative stress in the renal cortex of rats with diabetes mellitus.
Journal of the American Society of Nephrology : JASN 2001;12(8):1630-9.
2001: Hanafy K A; Krumenacker J S; Murad F
NO, nitrotyrosine, and cyclic GMP in signal transduction.
Medical science monitor : international medical journal of experimental and clinical research 2001;7(4):801-19.
2001: Marcondes S; Turko I V; Murad F
Nitration of succinyl-CoA:3-oxoacid CoA-transferase in rats after endotoxin administration.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(13):7146-51.
2001: Mailman D; Guntuku S; Bhuiyan M B; Murad F
Organ sites of lipopolysaccharide-induced nitric oxide production in the anesthetized rat.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2001;5(3):243-51.
2001: Bian K; Harari Y; Zhong M; Lai M; Castro G; Weisbrodt N; Murad F
Down-regulation of inducible nitric-oxide synthase (NOS-2) during parasite-induced gut inflammation: a path to identify a selective NOS-2 inhibitor.
Molecular pharmacology 2001;59(4):939-47.
2001: Krumenacker J S; Hyder S M; Murad F
Estradiol rapidly inhibits soluble guanylyl cyclase expression in rat uterus.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(2):717-22.
2001: Davis K L; Martin E; Turko I V; Murad F
Novel effects of nitric oxide.
Annual review of pharmacology and toxicology 2001;41():203-36.
2000: Chen Z J; Miao Z H; Vetter M; Dulin N; Liu S; Che D; Hughes B; Murad F; Douglas J; Chang C H
Molecular cloning of a regulatory protein for membrane-bound guanylate cyclase GC-A.
Biochemical and biophysical research communications 2000;278(1):106-11.
2000: Kildsgaard J; Hollmann T J; Matthews K W; Bian K; Murad F; Wetsel R A
Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5406-9.
2000: Lee Y C; Martin E; Murad F
Human recombinant soluble guanylyl cyclase: expression, purification, and regulation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(20):10763-8.
2000: Sharina I G; Krumenacker J S; Martin E; Murad F
Genomic organization of alpha1 and beta1 subunits of the mammalian soluble guanylyl cyclase genes.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(20):10878-83.
2000: Martin E; Davis K; Bian K; Lee Y C; Murad F
Cellular signaling with nitric oxide and cyclic guanosine monophosphate.
Seminars in perinatology 2000;24(1):2-6.
1999: Murad F
Cellular signaling with nitric oxide and cyclic GMP.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1999;32(11):1317-27.
1999: Balabanli B; Kamisaki Y; Martin E; Murad F
Requirements for heme and thiols for the nonenzymatic modification of nitrotyrosine.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13136-41.
1999: Bian K; Davis K; Kuret J; Binder L; Murad F
Nitrotyrosine formation with endotoxin-induced kidney injury detected by immunohistochemistry.
The American journal of physiology 1999;277(1 Pt 2):F33-40.
1999: Murad F
Discovery of some of the biological effects of nitric oxide and its role in cell signaling.
Bioscience reports 1999;19(3):133-54.
1998: Kamisaki Y; Wada K; Bian K; Balabanli B; Davis K; Martin E; Behbod F; Lee Y C; Murad F
An activity in rat tissues that modifies nitrotyrosine-containing proteins.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(20):11584-9.
1998: Murad F
Nitric oxide signaling: would you believe that a simple free radical could be a second messenger, autacoid, paracrine substance, neurotransmitter, and hormone?
Recent progress in hormone research 1998;53():43-59; discussion 59-60.
1997: Zanardo R C; Costa E; Ferreira H H; Antunes E; Martins A R; Murad F; De Nucci G
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):14111-4.
1997: Murad F
What are the molecular mechanisms for the antiproliferative effects of nitric oxide and cGMP in vascular smooth muscle?
Circulation 1997;95(5):1101-3.
1996: Murad F
The 1996 Albert Lasker Medical Research Awards. Signal transduction using nitric oxide and cyclic guanosine monophosphate.
JAMA : the journal of the American Medical Association 1996;276(14):1189-92.
1996: Papapetropoulos A; Abou-Mohamed G; Marczin N; Murad F; Caldwell R W; Catravas J D
Downregulation of nitrovasodilator-induced cyclic GMP accumulation in cells exposed to endotoxin or interleukin-1 beta.
British journal of pharmacology 1996;118(6):1359-66.
1996: Papapetropoulos A; Go C Y; Murad F; Catravas J D
Mechanisms of tolerance to sodium nitroprusside in rat cultured aortic smooth muscle cells.
British journal of pharmacology 1996;117(1):147-55.
1996: McDonald L J; Murad F
Nitric oxide and cyclic GMP signaling.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1996;211(1):1-6.
1995: Papapetropoulos A; Marczin N; Mora G; Milici A; Murad F; Catravas J D
Regulation of vascular smooth muscle soluble guanylate cyclase activity, mRNA, and protein levels by cAMP-elevating agents.
Hypertension 1995;26(4):696-704.
1995: Xie J; Roddy P; Rife T K; Murad F; Young A P
Two closely linked but separable promoters for human neuronal nitric oxide synthase gene transcription.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(4):1242-6.
1995: Young A P; Murad F; Vaessin H; Xie J; Rife T K
Transcription of the human neuronal nitric oxide synthase gene in the central nervous system is mediated by multiple promoters.
Advances in pharmacology (San Diego, Calif.) 1995;34():91-112.
1995: Buechler W A; Singh S; Aktas J; Müller S; Murad F; Gerzer R
High-level expression of biologically active soluble guanylate cyclase using the baculovirus system is strongly heme-dependent.
Advances in pharmacology (San Diego, Calif.) 1995;34():293-303.
1995: McDonald L J; Murad F
Nitric oxide and cGMP signaling.
Advances in pharmacology (San Diego, Calif.) 1995;34():263-75.
1995: Sheng H; Ishii K; Förstermann U; Murad F
Mechanism of bradykinin-induced cyclic GMP accumulation in bovine tracheal smooth muscle.
Lung 1995;173(6):373-83.
1994: Wendland B; Schweizer F E; Ryan T A; Nakane M; Murad F; Scheller R H; Tsien R W
Existence of nitric oxide synthase in rat hippocampal pyramidal cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2151-5.
1994: Tracey W R; Pollock J S; Murad F; Nakane M; Förstermann U
Identification of an endothelial-like type III NO synthase in LLC-PK1 kidney epithelial cells.
The American journal of physiology 1994;266(1 Pt 1):C22-8.
1994: Hirata M; Murad F
Interrelationships of cyclic GMP, inositol phosphates, and calcium.
Advances in pharmacology (San Diego, Calif.) 1994;26():195-216.
1994: Murad F
Cyclic GMP: synthesis, metabolism, and function. Introduction and some historical comments.
Advances in pharmacology (San Diego, Calif.) 1994;26():1-5.
1994: Nakane M; Murad F
Cloning of guanylyl cyclase isoforms.
Advances in pharmacology (San Diego, Calif.) 1994;26():7-18.
1994: Leitman D C; Waldman S A; Murad F
Regulation of particulate guanylate cyclase by natriuretic peptides and Escherichia coli heat-stable enterotoxin.
Advances in pharmacology (San Diego, Calif.) 1994;26():67-86.
1994: Murad F
Regulation of cytosolic guanylyl cyclase by nitric oxide: the NO-cyclic GMP signal transduction system.
Advances in pharmacology (San Diego, Calif.) 1994;26():19-33.
1994: Warner T D; Mitchell J A; Sheng H; Murad F
Effects of cyclic GMP on smooth muscle relaxation.
Advances in pharmacology (San Diego, Calif.) 1994;26():171-94.
1994: Murad F
The nitric oxide-cyclic GMP signal transduction system for intracellular and intercellular communication.
Recent progress in hormone research 1994;49():239-48.
1993: Pollock J S; Nakane M; Buttery L D; Martinez A; Springall D; Polak J M; Förstermann U; Murad F
Characterization and localization of endothelial nitric oxide synthase using specific monoclonal antibodies.
The American journal of physiology 1993;265(5 Pt 1):C1379-87.
1993: Sheng H; Gagne G D; Matsumoto T; Miller M F; Förstermann U; Murad F
Nitric oxide synthase in bovine superior cervical ganglion.
Journal of neurochemistry 1993;61(3):1120-6.
1993: Mitchell J A; Kohlhaas K L; Sorrentino R; Warner T D; Murad F; Vane J R
Induction by endotoxin of nitric oxide synthase in the rat mesentery: lack of effect on action of vasoconstrictors.
British journal of pharmacology 1993;109(1):265-70.
1993: Nakane M; Schmidt H H; Pollock J S; Förstermann U; Murad F
Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle.
FEBS letters 1993;316(2):175-80.
1993: Murad F; Forstermann U; Nakane M; Pollock J; Tracey R; Matsumoto T; Buechler W
The nitric oxide-cyclic GMP signal transduction system for intracellular and intercellular communication.
Advances in second messenger and phosphoprotein research 1993;28():101-9.
1992: Sheng H; Hughes M L; Murad F; Briggs C A
Evidence that nitric oxide mediates the cyclic GMP response to synaptic activity in the rat superior cervical ganglion.
Brain research 1992;597(2):343-5.
1992: Wilcox C S; Welch W J; Murad F; Gross S S; Taylor G; Levi R; Schmidt H H
Nitric oxide synthase in macula densa regulates glomerular capillary pressure.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):11993-7.
1992: Matsumoto T; Mitchell J A; Schmidt H H; Kohlhaas K L; Warner T D; Förstermann U; Murad F
Nitric oxide synthase in ferret brain: localization and characterization.
British journal of pharmacology 1992;107(3):849-52.
1992: Schmidt H H; Gagne G D; Nakane M; Pollock J S; Miller M F; Murad F
Mapping of neural nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not with soluble guanylyl cyclase, and novel paraneural functions for nitrinergic signal transduction.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992;40(10):1439-56.
1992: Pollock J S; Klinghofer V; Förstermann U; Murad F
Endothelial nitric oxide synthase is myristylated.
FEBS letters 1992;309(3):402-4.
1992: Yonemaru M; Ishii K; Murad F; Raffin T A
Atriopeptin-induced increases in endothelial cell permeability are associated with elevated cGMP levels.
The American journal of physiology 1992;263(3 Pt 1):L363-9.
1992: Warner T D; Budzik G P; Matsumoto T; Mitchell J A; Förstermann U; Murad F
Regional differences in endothelin converting enzyme activity in rat brain: inhibition by phosphoramidon and EDTA.
British journal of pharmacology 1992;106(4):948-52.
1992: Sheng H; Schmidt H H; Nakane M; Mitchell J A; Pollock J S; Föstermann U; Murad F
Characterization and localization of nitric oxide synthase in non-adrenergic non-cholinergic nerves from bovine retractor penis muscles.
British journal of pharmacology 1992;106(4):768-73.
1992: Hassall C J; Saffrey M J; Belai A; Hoyle C H; Moules E W; Moss J; Schmidt H H; Murad F; Förstermann U; Burnstock G
Nitric oxide synthase immunoreactivity and NADPH-diaphorase activity in a subpopulation of intrinsic neurones of the guinea-pig heart.
Neuroscience letters 1992;143(1-2):65-8.
1992: Belai A; Schmidt H H; Hoyle C H; Hassall C J; Saffrey M J; Moss J; Förstermann U; Murad F; Burnstock G
Colocalization of nitric oxide synthase and NADPH-diaphorase in the myenteric plexus of the rat gut.
Neuroscience letters 1992;143(1-2):60-4.
1992: Warner T D; Schmidt H H; Kuk J; Mitchell J A; Murad F
Human brain contains a metalloprotease that converts big endothelin-1 to endothelin-1 and is inhibited by phosphoramidon and EDTA.
British journal of pharmacology 1992;106(3):505-6.
1992: Schmidt H H; Pollock J S; Nakane M; Förstermann U; Murad F
Ca2+/calmodulin-regulated nitric oxide synthases.
Cell calcium 1992;13(6-7):427-34.
1992: Mitchell J A; Kohlhaas K L; Matsumoto T; Pollock J S; Förstermann U; Warner T D; Schmidt H H; Murad F
Induction of NADPH-dependent diaphorase and nitric oxide synthase activity in aortic smooth muscle and cultured macrophages.
Molecular pharmacology 1992;41(6):1163-8.
1992: Warner T D; Schmidt H H; Murad F
Interactions of endothelins and EDRF in bovine native endothelial cells: selective effects of endothelin-3.
The American journal of physiology 1992;262(5 Pt 2):H1600-5.
1992: Saffrey M J; Hassall C J; Hoyle C H; Belai A; Moss J; Schmidt H H; Förstermann U; Murad F; Burnstock G
Colocalization of nitric oxide synthase and NADPH-diaphorase in cultured myenteric neurones.
Neuroreport 1992;3(4):333-6.
1992: Schmidt H H; Warner T D; Nakane M; Förstermann U; Murad F
Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages.
Molecular pharmacology 1992;41(4):615-24.
1992: Schmidt H H; Warner T D; Murad F
Double-edged role of endogenous nitric oxide.
Lancet 1992;339(8799):986.
1992: Schmidt H H; Smith R M; Nakane M; Murad F
Ca2+/calmodulin-dependent NO synthase type I: a biopteroflavoprotein with Ca2+/calmodulin-independent diaphorase and reductase activities.
Biochemistry 1992;31(12):3243-9.
1992: Förstermann U; Schmidt H H; Kohlhaas K L; Murad F
Induced RAW 264.7 macrophages express soluble and particulate nitric oxide synthase: inhibition by transforming growth factor-beta.
European journal of pharmacology 1992;225(2):161-5.
1992: Schmidt H H; Warner T D; Ishii K; Sheng H; Murad F
Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides.
Science (New York, N.Y.) 1992;255(5045):721-3.
1992: Hu Z W; Honda K; Murad F; Hoffman B B
Prolonged exposure to catecholamines enhances sensitivity of smooth muscle relaxation induced by sodium nitroprusside and atriopeptin.
The Journal of pharmacology and experimental therapeutics 1992;260(2):756-61.
1992: Warner T D; Mitchell J A; D'Orleans-Juste P; Ishii K; Förstermann U; Murad F
Characterization of endothelin-converting enzyme from endothelial cells and rat brain: detection of the formation of biologically active endothelin-1 by rapid bioassay.
Molecular pharmacology 1992;41(2):399-403.
1992: Murad F; Forstermann U; Nakane M; Schmidt H; Pollock J; Sheng H; Matsumoto T; Warner T; Mitchell J; Tracey R
The nitric oxide-cyclic GMP signal transduction pathway in vascular smooth muscle preparations and other tissues.
Japanese journal of pharmacology 1992;58 Suppl 2():150P-157P.
1992: Pollock J S; Nakane M; Förstermann U; Murad F
Particulate and soluble bovine endothelial nitric oxide synthases are structurally similar proteins yet different from soluble brain nitric oxide synthase.
Journal of cardiovascular pharmacology 1992;20 Suppl 12():S50-3.
1992: Warner T D; Budzik G P; Mitchell J A; Huang Z J; Murad F
Detection by bioassay and specific enzyme-linked immunosorbent assay of phosphoramidon-inhibitable endothelin-converting activity in brain and endothelium.
Journal of cardiovascular pharmacology 1992;20 Suppl 12():S19-21.
1991: Schmidt H H; Murad F
Purification and characterization of a human NO synthase.
Biochemical and biophysical research communications 1991;181(3):1372-7.
1991: Pollock J S; Förstermann U; Mitchell J A; Warner T D; Schmidt H H; Nakane M; Murad F
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10480-4.
1991: Horio Y; Murad F
Purification of guanylyl cyclase from rod outer segments.
Biochimica et biophysica acta 1991;1133(1):81-8.
1991: Ishii K; Warner T D; Sheng H; Murad F
Endothelin increases cyclic GMP levels in LLC-PK1 porcine kidney epithelial cells via formation of an endothelium-derived relaxing factor-like substance.
The Journal of pharmacology and experimental therapeutics 1991;259(3):1102-8.
1991: Nakane M; Mitchell J; Förstermann U; Murad F
Phosphorylation by calcium calmodulin-dependent protein kinase II and protein kinase C modulates the activity of nitric oxide synthase.
Biochemical and biophysical research communications 1991;180(3):1396-402.
1991: Mitchell J A; Sheng H; Förstermann U; Murad F
Characterization of nitric oxide synthases in non-adrenergic non-cholinergic nerve containing tissue from the rat anococcygeus muscle.
British journal of pharmacology 1991;104(2):289-91.
1991: Förstermann U; Schmidt H H; Pollock J S; Sheng H; Mitchell J A; Warner T D; Nakane M; Murad F
Isoforms of nitric oxide synthase. Characterization and purification from different cell types.
Biochemical pharmacology 1991;42(10):1849-57.
1991: Fiscus R R; Zhou H L; Wang X; Han C; Ali S; Joyce C D; Murad F
Calcitonin gene-related peptide (CGRP)-induced cyclic AMP, cyclic GMP and vasorelaxant responses in rat thoracic aorta are antagonized by blockers of endothelium-derived relaxant factor (EDRF).
Neuropeptides 1991;20(2):133-43.
1991: Ishii K; Sheng H; Warner T D; Förstermann U; Murad F
A simple and sensitive bioassay method for detection of EDRF with RFL-6 rat lung fibroblasts.
The American journal of physiology 1991;261(2 Pt 2):H598-603.
1991: Sheng H; Ishii K; Murad F
Generation of an endothelium-derived relaxing factor-like substance in bovine tracheal smooth muscle.
The American journal of physiology 1991;260(6 Pt 1):L489-93.
1991: Mitchell J A; Förstermann U; Warner T D; Pollock J S; Schmidt H H; Heller M; Murad F
Endothelial cells have a particulate enzyme system responsible for EDRF formation: measurement by vascular relaxation.
Biochemical and biophysical research communications 1991;176(3):1417-23.
1991: Förstermann U; Pollock J S; Schmidt H H; Heller M; Murad F
Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(5):1788-92.
1991: Chen J; Chang B; Williams M; Murad F
Sodium nitroprusside degenerates cultured rat striatal neurons.
Neuroreport 1991;2(3):121-3.
1991: Horio Y; Murad F
Solubilization of guanylyl cyclase from bovine rod outer segments and effects of lowering Ca2+ and nitro compounds.
The Journal of biological chemistry 1991;266(6):3411-5.
1991: Schmidt H H; Pollock J S; Nakane M; Gorsky L D; Förstermann U; Murad F
Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(2):365-9.
1991: Buechler W A; Nakane M; Murad F
Expression of soluble guanylate cyclase activity requires both enzyme subunits.
Biochemical and biophysical research communications 1991;174(1):351-7.
1991: Ishii K; Chang B; Kerwin J F; Wagenaar F L; Huang Z J; Murad F
Formation of endothelium-derived relaxing factor in porcine kidney epithelial LLC-PK1 cells: an intra- and intercellular messenger for activation of soluble guanylate cyclase.
The Journal of pharmacology and experimental therapeutics 1991;256(1):38-43.
1991: Ishii K; Warner T D; Sheng H; Murad F
Endothelin-1 stimulates cyclic GMP formation in porcine kidney epithelial cells via activation of the L-arginine-dependent soluble guanylate cyclase pathway.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S246-50.
1991: Leitman D C; Waldman S A; Murad F
Identification of atrial natriuretic peptide receptors in cultured cells.
Methods in enzymology 1991;195():436-46.
1991: Waldman S A; Leitman D C; Murad F
Copurification of atrial natriuretic peptide receptor and particulate guanylyl cyclase.
Methods in enzymology 1991;195():397-404.
1991: Waldman S A; Leitman D C; Murad F
Immunoaffinity purification of soluble guanylyl cyclase.
Methods in enzymology 1991;195():391-6.
1990: Nakane M; Arai K; Saheki S; Kuno T; Buechler W; Murad F
Molecular cloning and expression of cDNAs coding for soluble guanylate cyclase from rat lung.
The Journal of biological chemistry 1990;265(28):16841-5.
1990: Förstermann U; Gorsky L D; Pollock J S; Ishii K; Schmidt H H; Heller M; Murad F
Hormone-induced biosynthesis of endothelium-derived relaxing factor/nitric oxide-like material in N1E-115 neuroblastoma cells requires calcium and calmodulin.
Molecular pharmacology 1990;38(1):7-13.
1990: Ishii K; Kerwin J F; Murad F
N omega-nitro-L-arginine: a potent inhibitor of the L-arginine-dependent soluble guanylate cyclase activation pathway in LLC-PK1 cells.
Canadian journal of physiology and pharmacology 1990;68(6):749-51.
1990: Chang C H; Kohse K P; Chang B; Hirata M; Jiang B; Douglas J E; Murad F
Characterization of ATP-stimulated guanylate cyclase activation in rat lung membranes.
Biochimica et biophysica acta 1990;1052(1):159-65.
1990: Förstermann U; Gorsky L D; Pollock J S; Schmidt H H; Heller M; Murad F
Regional distribution of EDRF/NO-synthesizing enzyme(s) in rat brain.
Biochemical and biophysical research communications 1990;168(2):727-32.
1990: Gorsky L D; Förstermann U; Ishii K; Murad F
Production of an EDRF-like activity in the cytosol of N1E-115 neuroblastoma cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990;4(5):1494-500.
1990: Saheki S; Kuno T; Tanaka C; Takeuchi N; Murad F
Radiation inactivation target-size analysis of soluble guanylate cyclase.
Biochimica et biophysica acta 1990;1051(3):306-9.
1990: Ishii K; Chang B; Kerwin J F; Huang Z J; Murad F
N omega-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation.
European journal of pharmacology 1990;176(2):219-23.
1990: Hirata M; Kohse K P; Chang C H; Ikebe T; Murad F
Mechanism of cyclic GMP inhibition of inositol phosphate formation in rat aorta segments and cultured bovine aortic smooth muscle cells.
The Journal of biological chemistry 1990;265(3):1268-73.
1990: Murad F; Ishii K; Förstermann U; Gorsky L; Kerwin J F; Pollock J; Heller M
EDRF is an intracellular second messenger and autacoid to regulate cyclic GMP synthesis in many cells.
Advances in second messenger and phosphoprotein research 1990;24():441-8.
1989: Förstermann U; Ishii K; Gorsky L D; Murad F
The cytosol of N1E-115 neuroblastoma cells synthesizes an EDRF-like substance that relaxes rabbit aorta.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(6 Pt 2):771-4.
1989: Waldman S A; Rapoport R M; Fiscus R R; Leitman D C; Chang L Y; Murad F
Regulation of particulate guanylate cyclase by atriopeptins: relation between peptide structure, receptor binding, and enzyme kinetics.
Biochimica et biophysica acta 1989;999(2):157-62.
1989: Waldman S A; Leitman D C; Chang L Y; Murad F
Comparison of particulate guanylate cyclase in cells with and without atrial natriuretic peptide receptor binding activity.
Molecular and cellular biochemistry 1989;90(1):19-25.
1989: Bennett B M; Leitman D C; Schröder H; Kawamoto J H; Nakatsu K; Murad F
Relationship between biotransformation of glyceryl trinitrate and cyclic GMP accumulation in various cultured cell lines.
The Journal of pharmacology and experimental therapeutics 1989;250(1):316-23.
1989: Hirata M; Chang C H; Murad F
Stimulatory effects of atrial natriuretic factor on phosphoinositide hydrolysis in cultured bovine aortic smooth muscle cells.
Biochimica et biophysica acta 1989;1010(3):346-51.
1989: Rapoport R M; Ashraf M; Murad F
Effects of melittin on endothelium-dependent relaxation and cyclic GMP levels in rat aorta.
Circulation research 1989;64(3):463-73.
1989: Ishii K; Murad F
ANP relaxes bovine tracheal smooth muscle and increases cGMP.
The American journal of physiology 1989;256(3 Pt 1):C495-500.
1988: Nakane M; Saheki S; Kuno T; Ishii K; Murad F
Molecular cloning of a cDNA coding for 70 kilodalton subunit of soluble guanylate cyclase from rat lung.
Biochemical and biophysical research communications 1988;157(3):1139-47.
1988: Bennett B M; Schröder H; Hayward L D; Waldman S A; Murad F
Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation, and guanylate cyclase activation by glyceryl trinitrate and the enantiomers of isoidide dinitrate.
Circulation research 1988;63(4):693-701.
1988: Murad F
Role of cyclic GMP in the mechanism of action of nitrovasodilators, endothelium-dependent agents and atrial natriuretic peptide.
Biochemical Society transactions 1988;16(4):490-2.
1988: Molina C R; Fowler M B; McCrory S; Peterson C; Myers B D; Schroeder J S; Murad F
Hemodynamic, renal and endocrine effects of atrial natriuretic peptide infusion in severe heart failure.
Journal of the American College of Cardiology 1988;12(1):175-86.
1988: Song D L; Kohse K P; Murad F
Brain natriuretic factor. Augmentation of cellular cyclic GMP, activation of particulate guanylate cyclase and receptor binding.
FEBS letters 1988;232(1):125-9.
1988: Waldman S A; Leitman D C; Andresen J; Murad F
Guanylate cyclase and the adrenal natriuretic factor receptor.
Science (New York, N.Y.) 1988;240(4853):805-6.
1988: Schröder H; Leitman D C; Bennett B M; Waldman S A; Murad F
Glyceryl trinitrate-induced desensitization of guanylate cyclase in cultured rat lung fibroblasts.
The Journal of pharmacology and experimental therapeutics 1988;245(2):413-8.
1988: Myers B D; Peterson C; Molina C; Tomlanovich S J; Newton L D; Nitkin R; Sandler H; Murad F
Role of cardiac atria in the human renal response to changing plasma volume.
The American journal of physiology 1988;254(4 Pt 2):F562-73.
1988: Leitman D C; Agnost V L; Catalano R M; Schröder H; Waldman S A; Bennett B M; Tuan J J; Murad F
Atrial natriuretic peptide, oxytocin, and vasopressin increase guanosine 3',5'-monophosphate in LLC-PK1 kidney epithelial cells.
Endocrinology 1988;122(4):1478-85.
1988: Leitman D C; Andresen J W; Catalano R M; Waldman S A; Tuan J J; Murad F
Atrial natriuretic peptide binding, cross-linking, and stimulation of cyclic GMP accumulation and particulate guanylate cyclase activity in cultured cells.
The Journal of biological chemistry 1988;263(8):3720-8.
1988: Fiscus R R; Murad F
cGMP-dependent protein kinase activation in intact tissues.
Methods in enzymology 1988;159():150-9.
1988: Murad F; Leitman D; Waldman S; Chang C H; Hirata M; Kohse K
Effects of nitrovasodilators, endothelium-dependent vasodilators, and atrial peptides on cGMP.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():1005-9.
1988: Rapoport R M; Murad F
Effects of ethacrynic acid and cystamine on sodium nitroprusside-induced relaxation, cyclic GMP levels and guanylate cyclase activity in rat aorta.
General pharmacology 1988;19(1):61-5.
1988: Waldman S A; Murad F
Biochemical mechanisms underlying vascular smooth muscle relaxation: the guanylate cyclase-cyclic GMP system.
Journal of cardiovascular pharmacology 1988;12 Suppl 5():S115-8.
1987: Molina C R; Andresen J W; Rapoport R M; Waldman S; Murad F
Effect of in vivo nitroglycerin therapy on endothelium-dependent and independent vascular relaxation and cyclic GMP accumulation in rat aorta.
Journal of cardiovascular pharmacology 1987;10(4):371-8.
1987: Murad F; Leitman D C; Bennett B M; Molina C; Waldman S A
Regulation of guanylate cyclase by atrial natriuretic factor and the role of cyclic GMP in vasodilation.
The American journal of the medical sciences 1987;294(3):139-43.
1987: Waldman S A; Murad F
Cyclic GMP synthesis and function.
Pharmacological reviews 1987;39(3):163-96.
1987: Rapoport R M; Waldman S A; Ginsburg R; Molina C R; Murad F
Effects of glyceryl trinitrate on endothelium-dependent and -independent relaxation and cyclic GMP levels in rat aorta and human coronary artery.
Journal of cardiovascular pharmacology 1987;10(1):82-9.
1987: Leitman D C; Agnost V L; Tuan J J; Andresen J W; Murad F
Atrial natriuretic factor and sodium nitroprusside increase cyclic GMP in cultured rat lung fibroblasts by activating different forms of guanylate cyclase.
The Biochemical journal 1987;244(1):69-74.
1987: Leitman D C; Murad F
Atrial natriuretic factor receptor heterogeneity and stimulation of particulate guanylate cyclase and cyclic GMP accumulation.
Endocrinology and metabolism clinics of North America 1987;16(1):79-105.
1987: Fiscus R R; Robles B T; Waldman S A; Murad F
Atrial natriuretic factors stimulate accumulation and efflux of cyclic GMP in C6-2B rat glioma and PC12 rat pheochromocytoma cell cultures.
Journal of neurochemistry 1987;48(2):522-8.
1987: Murad F; Waldman S; Molina C; Bennett B; Leitman D
Regulation and role of guanylate cyclase-cyclic GMP in vascular relaxation.
Progress in clinical and biological research 1987;249():65-76.
1986: Kamisaki Y; Waldman S A; Murad F
The involvement of catalytic site thiol groups in the activation of soluble guanylate cyclase by sodium nitroprusside.
Archives of biochemistry and biophysics 1986;251(2):709-14.
1986: Waldman S A; Rapoport R M; Ginsburg R; Murad F
Desensitization to nitroglycerin in vascular smooth muscle from rat and human.
Biochemical pharmacology 1986;35(20):3525-31.
1986: Leitman D C; Andresen J W; Kuno T; Kamisaki Y; Chang J K; Murad F
Identification of multiple binding sites for atrial natriuretic factor by affinity cross-linking in cultured endothelial cells.
The Journal of biological chemistry 1986;261(25):11650-5.
1986: Murad F
Cyclic guanosine monophosphate as a mediator of vasodilation.
The Journal of clinical investigation 1986;78(1):1-5.
1986: Kamisaki Y; Saheki S; Nakane M; Palmieri J A; Kuno T; Chang B Y; Waldman S A; Murad F
Soluble guanylate cyclase from rat lung exists as a heterodimer.
The Journal of biological chemistry 1986;261(16):7236-41.
1986: Rapoport R M; Ginsburg R; Waldman S A; Murad F
Effects of atriopeptins on relaxation and cyclic GMP levels in human coronary artery in vitro.
European journal of pharmacology 1986;124(1-2):193-6.
1986: Leitman D C; Fiscus R R; Murad F
Forskolin, phosphodiesterase inhibitors, and cyclic AMP analogs inhibit proliferation of cultured bovine aortic endothelial cells.
Journal of cellular physiology 1986;127(2):237-43.
1986: Kuno T; Andresen J W; Kamisaki Y; Waldman S A; Chang L Y; Saheki S; Leitman D C; Nakane M; Murad F
Co-purification of an atrial natriuretic factor receptor and particulate guanylate cyclase from rat lung.
The Journal of biological chemistry 1986;261(13):5817-23.
1986: Kuno T; Kamisaki Y; Waldman S A; Gariepy J; Schoolnik G; Murad F
Characterization of the receptor for heat-stable enterotoxin from Escherichia coli in rat intestine.
The Journal of biological chemistry 1986;261(3):1470-6.
1986: Rapoport R M; Winquist R J; Baskin E P; Faison E P; Waldman S A; Murad F
Effects of atriopeptins on relaxation and cyclic GMP levels in rat and rabbit aortas.
European journal of pharmacology 1986;120(1):123-6.
1986: Leitman D C; Murad F
Comparison of binding and cyclic GMP accumulation by atrial natriuretic peptides in endothelial cells.
Biochimica et biophysica acta 1986;885(1):74-9.
1986: Waldman S A; Kuno T; Kamisaki Y; Chang L Y; Gariepy J; O'Hanley P; Schoolnik G; Murad F
Intestinal receptor for heat-stable enterotoxin of Escherichia coli is tightly coupled to a novel form of particulate guanylate cyclase.
Infection and immunity 1986;51(1):320-6.
1986: Draznin M B; Rapoport R M; Murad F
Myosin light chain phosphorylation in contraction and relaxation of intact rat thoracic aorta.
The International journal of biochemistry 1986;18(10):917-28.
1986: Leitman D C; Andresen J W; Kuno T; Kamisaki Y; Chang J K; Murad F
Identification of two binding sites for atrial natriuretic factor in endothelial cells: evidence for a receptor subtype coupled to guanylate cyclase.
Transactions of the Association of American Physicians 1986;99():103-13.
1986: Murad F; Waldman S A; Fiscus R R; Rapoport R M
Regulation of cyclic GMP synthesis and the interactions with calcium.
Journal of cardiovascular pharmacology 1986;8 Suppl 8():S57-60.
1985: Rapoport R M; Waldman S A; Schwartz K; Winquist R J; Murad F
Effects of atrial natriuretic factor, sodium nitroprusside, and acetylcholine on cyclic GMP levels and relaxation in rat aorta.
European journal of pharmacology 1985;115(2-3):219-29.
1985: Fiscus R R; Rapoport R M; Waldman S A; Murad F
Atriopeptin II elevates cyclic GMP, activates cyclic GMP-dependent protein kinase and causes relaxation in rat thoracic aorta.
Biochimica et biophysica acta 1985;846(1):179-84.
1985: Rapoport R M; Schwartz K; Murad F
Effect of sodium-potassium pump inhibitors and membrane-depolarizing agents on sodium nitroprusside-induced relaxation and cyclic guanosine monophosphate accumulation in rat aorta.
Circulation research 1985;57(1):164-70.
1985: Waldman S A; Rapoport R M; Fiscus R R; Murad F
Effects of atriopeptin on particulate guanylate cyclase from rat adrenal.
Biochimica et biophysica acta 1985;845(2):298-303.
1985: Rapoport R M; Schwartz K; Murad F
Effects of Na+,K+-pump inhibitors and membrane depolarizing agents on acetylcholine-induced endothelium-dependent relaxation and cyclic GMP accumulation in rat aorta.
European journal of pharmacology 1985;110(2):203-9.
1985: Leitman D C; Waldman S A; Rapoport R M; Murad F
Specific atrial natriuretic factor receptors mediate increased cyclic GMP accumulation in cultured bovine aortic endothelial and smooth muscle cells.
Transactions of the Association of American Physicians 1985;98():243-52.
1985: Waldman S A; Chang L Y; Murad F
A two-step procedure for obtaining highly purified particulate guanylate cyclase from rat lung.
Preparative biochemistry 1985;15(3):103-19.
1985: Murad F; Rapoport R M; Fiscus R
Role of cyclic-GMP in relaxations of vascular smooth muscle.
Journal of cardiovascular pharmacology 1985;7 Suppl 3():S111-8.
1984: Winquist R J; Faison E P; Waldman S A; Schwartz K; Murad F; Rapoport R M
Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(23):7661-4.
1984: Waldman S A; Rapoport R M; Murad F
Atrial natriuretic factor selectively activates particulate guanylate cyclase and elevates cyclic GMP in rat tissues.
The Journal of biological chemistry 1984;259(23):14332-4.
1984: Pearl R G; Rosenthal M H; Murad F; Ashton J P
Aminophylline potentiates sodium nitroprusside-induced hypotension in the dog.
Anesthesiology 1984;61(6):712-5.
1984: Rapoport R M; Draznin M B; Murad F
Mechanisms of adenosine triphosphate-, thrombin-, and trypsin-induced relaxation of rat thoracic aorta.
Circulation research 1984;55(4):468-79.
1984: Rapoport R M; Murad F
Effect of cyanide on nitrovasodilator-induced relaxation, cyclic GMP accumulation and guanylate cyclase activation in rat aorta.
European journal of pharmacology 1984;104(1-2):61-70.
1984: Waldman S A; Sinacore M S; Lewicki J A; Chang L Y; Murad F
Selective activation of particulate guanylate cyclase by a specific class of porphyrins.
The Journal of biological chemistry 1984;259(7):4038-42.
1984: Waldman S A; O'Hanley P; Falkow S; Schoolnik G; Murad F
A simple, sensitive, and specific assay for the heat-stable enterotoxin of Escherichia coli.
The Journal of infectious diseases 1984;149(1):83-9.
1983: Rapoport R M; Draznin M B; Murad F
Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation.
Nature 1983;306(5939):174-6.
1983: Rapoport R M; Murad F
Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.
Circulation research 1983;52(3):352-7.
1983: Lewicki J A; Chang B; Murad F
Quantification of guanylate cyclase concentrations by a direct double determinant tandem immunoradiometric assay.
The Journal of biological chemistry 1983;258(6):3509-15.
1983: Rapoport R M; Murad F
Effect of ouabain and alterations in potassium concentration on relaxation induced by sodium nitroprusside.
Blood vessels 1983;20(5):255-64.
1983: Rapoport R M; Draznin M B; Murad F
Endothelium-dependent vasodilator-and nitrovasodilator-induced relaxation may be mediated through cyclic GMP formation and cyclic GMP-dependent protein phosphorylation.
Transactions of the Association of American Physicians 1983;96():19-30.
1983: Rapoport R M; Murad F
Endothelium-dependent and nitrovasodilator-induced relaxation of vascular smooth muscle: role of cyclic GMP.
Journal of cyclic nucleotide and protein phosphorylation research 1983;9(4-5):281-96.
1983: Waldman S A; Lewicki J A; Chang L Y; Murad F
Highly purified particulate guanylate cyclase from rat lung: characterization and comparison with soluble guanylate cyclase.
Molecular and cellular biochemistry 1983;57(2):155-66.
1983: Fiscus R R; Rapoport R M; Murad F
Endothelium-dependent and nitrovasodilator-induced activation of cyclic GMP-dependent protein kinase in rat aorta.
Journal of cyclic nucleotide and protein phosphorylation research 1983;9(6):415-25.
1982: Rapoport R M; Draznin M B; Murad F
Sodium nitroprusside-induced protein phosphorylation in intact rat aorta is mimicked by 8-bromo cyclic GMP.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(21):6470-4.
1982: Greenberg R N; Guerrant R L; Chang B; Robertson D C; Murad F
Inhibition of Escherichia coli heat-stable enterotoxin effects on intestinal guanylate cyclase and fluid secretion by quinacrine.
Biochemical pharmacology 1982;31(11):2005-9.
1982: Ariano M A; Lewicki J A; Brandwein H J; Murad F
Immunohistochemical localization of guanylate cyclase within neurons of rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(4):1316-20.
1982: Brandwein H J; Lewicki J A; Waldman S A; Murad F
Effect of GTP analogues on purified soluble guanylate cyclase.
The Journal of biological chemistry 1982;257(3):1309-11.
1982: Greenberg R N; Murad F; Guerrant R L
Lanthanum chloride inhibition of the secretory response to Escherichia coli heat-stable enterotoxin.
Infection and immunity 1982;35(2):483-8.
1982: Waldman S A; Lewicki J A; Brandwein H J; Murad F
Partial purification and characterization of particulate guanylate cyclase from rat liver after solubilization with trypsin.
Journal of cyclic nucleotide research 1982;8(6):359-70.
1982: Lewicki J A; Brandwein H J; Mittal C K; Arnold W P; Murad F
Properties of purified soluble guanylate cyclase activated by nitric oxide and sodium nitroprusside.
Journal of cyclic nucleotide research 1982;8(1):17-25.
1981: Brandwein H; Lewicki J; Murad F
Production and characterization of monoclonal antibodies to soluble rat lung guanylate cyclase.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(7):4241-5.
1981: Brandwein H J; Lewicki J A; Murad F
Reversible inactivation of guanylate cyclase by mixed disulfide formation.
The Journal of biological chemistry 1981;256(6):2958-62.
1981: Dohi T; Murad F
Effects of pyruvate and other metabolites on cyclic GMP levels in incubations of rat hepatocytes and kidney cortex.
Biochimica et biophysica acta 1981;673(1):14-25.
1981: Murad F; Lewicki J A; Brandwein H J; Mittal C K; Waldman S A
Guanylate cyclase: purification, properties, free radical activation, radiolabeling, and preparation of hybridoma antibodies.
Advances in cyclic nucleotide research 1981;14():229-39.
1980: Thorner M O; Hackett J T; Murad F; MacLeod R M
Calcium rather than cyclic AMP as the physiological intracellular regulator of prolactin release.
Neuroendocrinology 1980;31(6):390-402.
1980: Brooker G; Murad F
Automated "Gamma-flo" radioimmunoassay of urinary cyclic AMP.
Clinical chemistry 1980;26(12):1738-40.
1980: Greenberg R N; Murad F; Chang B; Robertson D C; Guerrant R L
Inhibition of Escherichia coli heat-stable enterotoxin by indomethacin and chlorpromazine.
Infection and immunity 1980;29(3):908-13.
1980: Guerrant R L; Hughes J M; Chang B; Robertson D C; Murad F
Activation of intestinal guanylate cyclase by heat-stable enterotoxin of Escherichia coli: studies of tissue specificity, potential receptors, and intermediates.
The Journal of infectious diseases 1980;142(2):220-8.
1980: Lewicki J A; Brandwein H J; Waldman S A; Murad F
Purified guanylate cyclase: characterization, iodination and preparation of monoclonal antibodies.
Journal of cyclic nucleotide research 1980;6(4):283-96.
1979: Braughler J M; Mittal C K; Murad F
Effects of thiols, sugars, and proteins on nitric oxide activation of guanylate cyclase.
The Journal of biological chemistry 1979;254(24):12450-4.
1979: Ichihara K; El-Zayat M; Mittal C K; Murad F
Fatty acid activation of guanylate cyclase from fibroblasts and liver.
Archives of biochemistry and biophysics 1979;197(1):44-51.
1979: Mittal C K; Braughler J M; Ichihara K; Murad F
Synthesis of adenosine 3',5'-monophosphate by guanylate cyclase, a new pathway for its formation.
Biochimica et biophysica acta 1979;585(3):333-42.
1979: Ichihara K; Murad F
Guanylate cyclase activity in rat liver and other tissues with starvation and streptozotocin-induced diabetes mellitus.
Archives of biochemistry and biophysics 1979;194(1):292-8.
1979: Neer E J; Murad F
Separation of soluble adenylate and guanylate cyclases from the mature rat testis.
Biochimica et biophysica acta 1979;583(4):531-4.
1979: Murad F; Arnold W P; Mittal C K; Braughler J M
Properties and regulation of guanylate cyclase and some proposed functions for cyclic GMP.
Advances in cyclic nucleotide research 1979;11():175-204.
1979: Garbers D L; Murad F
Guanylate cyclase assay methods.
Advances in cyclic nucleotide research 1979;10():57-67.
1978: Hughes J M; Murad F; Chang B; Guerrant R L
Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli.
Nature 1978;271(5647):755-6.
1978: Bergman M J; Guerrant R L; Murad F; Richardson S H; Weaver D; Mandell G L
Interaction of polymorphonuclear neutrophils with Escherichia coli. Effect of enterotoxin on phagocytosis, killing, chemotaxis, and cyclic AMP.
The Journal of clinical investigation 1978;61(2):227-34.
1978: Mittal C K; Arnold W P; Murad F
Characterization of protein inhibitors of guanylate cyclase activation from rat heart and bovine lung.
The Journal of biological chemistry 1978;253(4):1266-71.
1978: Murad F; Mittal C K; Arnold W P; Katsuki S; Kimura H
Guanylate cyclase: activation by azide, nitro compounds, nitric oxide, and hydroxyl radical and inhibition by hemoglobin and myoglobin.
Advances in cyclic nucleotide research 1978;9():145-58.
1977: Mittal C K; Murad F
Properties and oxidative regulation of guanylate cyclase.
Journal of cyclic nucleotide research 1977;3(6):381-91.
1977: Arnold W P; Aldred R; Murad F
Cigarette smoke activates guanylate cyclase and increases guanosine 3',5'-monophosphate in tissues.
Science (New York, N.Y.) 1977;198(4320):934-6.
1977: Mittal C K; Murad F
Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(10):4360-4.
1977: Katsuki S; Arnold W P; Murad F
Effects of sodium nitroprusside, nitroglycerin, and sodium azide on levels of cyclic nucleotides and mechanical activity of various tissues.
Journal of cyclic nucleotide research 1977;3(4):239-47.
1977: Arnold W P; Mittal C K; Katsuki S; Murad F
Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(8):3203-7.
1977: Mittal C K; Kimura H; Murad F
Purification and properties of a protein required for sodium azide activation of guanylate cyclase.
The Journal of biological chemistry 1977;252(12):4384-90.
1977: Mittal C K; Murad F
Formation of adenosine 3':5'-monophosphate by preparations of guanylate cyclase from rat liver and other tissues.
The Journal of biological chemistry 1977;252(10):3136-40.
1977: Ichihara K; Larner J; Kimura H; Murad F
Activation of liver guanylate cyclase by bile salts and contaminants in crude secretin and pancreozymin preparations.
Biochimica et biophysica acta 1977;481(2):734-40.
1977: Katsuki S; Murad F
Regulation of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate levels and contractility in bovine tracheal smooth muscle.
Molecular pharmacology 1977;13(2):330-41.
1977: Katsuki S; Arnold W; Mittal C; Murad F
Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine.
Journal of cyclic nucleotide research 1977;3(1):23-35.
1976: Kimura H; Mittal C K; Murad F
Appearance of magnesium guanylate cyclase activity in rat liver with sodium azide activation.
The Journal of biological chemistry 1976;251(24):7769-73.
1976: Criss W E; Murad F; Kimura H; Morris H P
Properties of guanylate cyclase in adult rat liver and several Morris hepatomas.
Biochimica et biophysica acta 1976;445(2):500-8.
1976: Criss W E; Murad F
Urinary excretion of cyclic guanosine 3':5'-monophosphate and cyclic adenosine 3':5'-monophosphate in rats bearing transplantable liver and kidney tumors.
Cancer research 1976;36(5):1714-6.
1976: Criss W E; Murad F; Kimura H
Properties of guanylate cyclase from rat kidney cortex and transplantable kidney tumors.
Journal of cyclic nucleotide research 1976;2(1):11-9.
1975: Kimura H; Mittal C K; Murad F
Increases in cyclic GMP levels in brain and liver with sodium azide an activator of guanylate cyclase.
Nature 1975;257(5528):700-2.
1975: Kimura H; Mittal C K; Murad F
Activation of guanylate cyclase from rat liver and other tissues by sodium azide.
The Journal of biological chemistry 1975;250(20):8016-22.
1975: Murad F; Kimura H; Hopkins H A; Looney W B; Kovacs C J
Increased urinary excretion of cyclic guanosine monophosphate in rats bearing Morris hepatoma 3924A.
Science (New York, N.Y.) 1975;190(4209):58-60.
1975: Kimura H; Murad F
Subcellular localization of guanylate cyclase.
Life sciences 1975;17(6):837-43.
1975: Kimura H; Murad F
Localization of particulate guanylate cyclase in plasma membranes and microsomes of rat liver.
The Journal of biological chemistry 1975;250(12):4810-7.
1975: Kimura H; Murad F
Increased particulate and decreased soluble guanylate cyclase activity in regenerating liver, fetal liver, and hepatoma.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(5):1965-9.
1975: Murad F; Moss W W; Johanson J; Selden R F
Urinary excretion of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate in normal children and those with cystic fibrosis.
The Journal of clinical endocrinology and metabolism 1975;40(4):552-9.
1975: Kimura H; Murad F
Two forms of guanylate cyclase in mammalian tissues and possible mechanisms for their regulation.
Metabolism: clinical and experimental 1975;24(3):439-45.
1975: McLean M J; Lapsley R A; Shigenobu K; Murad F; Sperelakis N
High cyclic AMP levels in young chick embryonic hearts.
Developmental biology 1975;42(1):196-201.
1975: Mittal C K; Kimura H; Murad F
Requirement for a macromolecular factor for sodium azide activation of guanulate cyclase.
Journal of cyclic nucleotide research 1975;1(6):261-9.
1974: Murad F
Mechanism of action of some bronchodilators. Cyclic nucleotide metabolism in tracheal preparations.
The American review of respiratory disease 1974;110(6 Pt 2):111-8.
1974: Kimura H; Murad F
Evidence for two different forms of guanylate cyclase in rat heart.
The Journal of biological chemistry 1974;249(21):6910-6.
1974: Kimura H; Thomas E; Murad F
Effects of decapitation, ether and pentobarbital on guanosine 3',5'-phosphate and adenosine 3',5'-phosphate levels in rat tissues.
Biochimica et biophysica acta 1974;343(3):519-28.
1974: Murad F; Kimura H
Cyclic nucleotide levels in incubations of guinea pig trachea.
Biochimica et biophysica acta 1974;343(2):275-86.
1974: Kimura H; Murad F
Nonenzymatic formation of guanosine 3':5'-monophosphate from guanosine triphosphate.
The Journal of biological chemistry 1974;249(1):329-31.
1974: Gilman A G; Murad F
Assay of cyclic nucleotides by receptor protein binding displacement.
Methods in enzymology 1974;38():49-61.
1974: Murad F
Techniques for the formation, partial purification, and assay of a cyclic AMP inhibitor.
Methods in enzymology 1974;38():273-83.
1973: Murad F
Beta-blockade of epinephrine-induced cyclic AMP formation in heart, liver, fat and trachea.
Biochimica et biophysica acta 1973;304(1):181-7.
1973: Thomas E W; Murad F; Looney W B; Morris H P
Adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate: concentrations in Morris hepatomas of different growth rates.
Biochimica et biophysica acta 1973;297(2):564-7.
1973: Murad F
Clinical studies and applications of cyclic nucleotides.
Advances in cyclic nucleotide research 1973;3():355-83.
1972: Murad F; Pak C Y
Urinary excretion of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate.
The New England journal of medicine 1972;286(26):1382-7.
1971: Murad F; Gilman A G
Adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate: a simultaneous protein binding assay.
Biochimica et biophysica acta 1971;252(2):397-400.
1971: Manganiello V C; Murad F; Vaughan M
Effects of lipolytic and antilipolytic agents on cyclic 3',5'-adenosine monophosphate in fat cells.
The Journal of biological chemistry 1971;246(7):2195-202.
1971: Murad F; Manganiello V; Vaughan M
A simple, sensitive protein-binding assay for guanosine 3':5'-monophosphate.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(4):736-9.
1970: Stossel T P; Murad F; Mason R J; Vaughan M
Regulation of glycogen metabolism in polymorphonuclear leukocytes.
The Journal of biological chemistry 1970;245(22):6228-34.
1970: Murad F; Manganiello V; Vaughan M
Effects of guanosine 3',5'-monophosphate on glycerol production and accumulation of adenosine 3',5'-monophosphate by fat cells.
The Journal of biological chemistry 1970;245(13):3352-60.
1969: Murad F; Rall T W; Vaughan M
Conditions for the formation, partial purification and assay of an inhibitor of adenosine 3',5'-monophosphate.
Biochimica et biophysica acta 1969;192(3):430-45.
1969: Vaughan M; Murad F
Adenyl cyclase activity in particles from fat cells.
Biochemistry 1969;8(7):3092-9.
1969: Murad F; Vaughan M
Effect of glucagon on rat heart adenyl cyclase.
Biochemical pharmacology 1969;18(5):1053-9.
1968: Murad F
Effect of glucagon on heart.
The New England journal of medicine 1968;279(8):434-5.
1962: MURAD F; CHI Y M; RALL T W; SUTHERLAND E W
Adenyl cyclase. III. The effect of catecholamines and choline esters on the formation of adenosine 3',5'-phosphate by preparations from cardiac muscle and liver.
The Journal of biological chemistry 1962;237():1233-8.

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