Akira Murakami

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Higuchi Maiko; Kobori Akio; Yamayoshi Asako; Murakami Akira
Synthesis of antisense oligonucleotides containing 2'-O-psoralenylmethoxyalkyl adenosine for photodynamic regulation of point mutations in RNA.
Waki Reiko; Ueda Takako; Yamayoshi Asako; Kobori Akio; Murakami Akira
Real-time monitoring of mRNAs with fluorescence-modified RNA probes in living cells.
Yamayoshi Asako; Momokawa Daiki; Kobori Akio; Murakami Akira
Development of peptide-oligonucleotide conjugates for regulation of small RNA function.

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All Publications

2009: Higuchi Maiko; Kobori Akio; Yamayoshi Asako; Murakami Akira
Synthesis of antisense oligonucleotides containing 2'-O-psoralenylmethoxyalkyl adenosine for photodynamic regulation of point mutations in RNA.
Bioorganic & medicinal chemistry 2009;17(2):475-83.
2009: Waki Reiko; Ueda Takako; Yamayoshi Asako; Kobori Akio; Murakami Akira
Real-time monitoring of mRNAs with fluorescence-modified RNA probes in living cells.
Nucleic acids symposium series (2004) 2009;(53):153-4.
2009: Yamayoshi Asako; Momokawa Daiki; Kobori Akio; Murakami Akira
Development of peptide-oligonucleotide conjugates for regulation of small RNA function.
Nucleic acids symposium series (2004) 2009;(53):53-4.
2008: Sakamoto Takashi; Kobori Akio; Murakami Akira
Microarray-based label-free detection of RNA using bispyrene-modified 2'-O-methyl oligoribonucleotide as capture and detection probe.
Bioorganic & medicinal chemistry letters 2008;18(8):2590-3.
2008: Higuchi Maiko; Yamayoshi Asako; Kobori Akio; Murakami Akira
Photodynamic antisense regulation of mRNA having a point mutation with psoralen-conjugated oligonucleotide.
Nucleic acids symposium series (2004) 2008;(52):515-6.
2008: Kobori Akio; Morita Junpei; Ikeda Masato; Yamayoshi Asako; Murakami Akira
Sequence-selective fluorophore formation by furan-conjugated oligodeoxyribonucleotides.
Nucleic acids symposium series (2004) 2008;(52):235-6.
2007: Sakamoto Takashi; Kobori Akio; Shigezawa Masako; Amitani Yasutaka; Higuchi Maiko; Murakami Akira
Homogeneous fluorescence assays for RNA diagnosis by pyrene-conjugated 2'-O-methyloligoribonucleotides.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1659-64.
2007: Higuchi Maiko; Yamayoshi Asako; Kobori Akio; Murakami Akira
Selective regulation of mutant K-ras mRNA expression by photo-cross-linking antisense oligonucleotide.
Nucleic acids symposium series (2004) 2007;(51):443-4.
2007: Kobori Akio; Mori Takashi; Yamayoshi Asako; Murakami Akira
Synthesis of naphthyridine-conjugated DNA probes and their application to SNPs typing.
Nucleic acids symposium series (2004) 2007;(51):309-10.
2007: Yamayoshi Asako; Shimazu Noriko; Higuchi Maiko; Kobori Akio; Murakami Akira
Gene regulation by decoy approach (II): Development of photo-cross-linked oligonucleotides duplex as a decoy DNA for estrogen receptor.
Nucleic acids symposium series (2004) 2007;(51):91-2.
2007: Higuchi Maiko; Yamayoshi Asako; Yamaguchi Takasei; Iwase Reiko; Yamaoka Tetsuji; Kobori Akio; Murakami Akira
Selective photo-cross-linking of 2'-O-psoralen-conjugated oligonucleotide with RNAs having point mutations.
Nucleosides, nucleotides & nucleic acids 2007;26(3):277-90.
2006: Kitagawa Tatsuya; Yamaoka Tetsuji; Iwase Reiko; Murakami Akira
Three-dimensional cell seeding and growth in radial-flow perfusion bioreactor for in vitro tissue reconstruction.
Biotechnology and bioengineering 2006;93(5):947-54.
2006: Higuchi Maiko; Sakamoto Takashi; Kobori Akio; Murakami Akira
Properties of novel antisense oligonucleotides containing 2'-O-modified adenosine with a photo-reactive group.
Nucleic acids symposium series (2004) 2006;(50):301-2.
2006: Sakamoto Takashi; Kobori Akio; Murakami Akira
Solid-phase detection of RNA using bispyrene-modified RNA probe.
Nucleic acids symposium series (2004) 2006;(50):215-6.
2006: Kobori Akio; Kobuchi Takashi; Ikeda Masato; Murakami Akira
Synthesis and cross-linking activities of oligodeoxynucleotides containing a 4-oxoalkenal group.
Nucleic acids symposium series (2004) 2006;(50):59-60.
2005: Sakamoto Takashi; Mahara Atsushi; Yamagata Koichi; Iwase Reiko; Yamaoka Tetsuji; Murakami Akira
Evaluation of dynamic features of Escherichia coli 16S ribosomal RNA in homogeneous physiological solution.
Biophysical journal 2005;89(6):4122-8.
2005: Sakamoto Takashi; Mahara Atsushi; Iwase Reiko; Yamaoka Tetsuji; Murakami Akira
Analytical method for estimation of kinetics of oligonucleotide/RNA hybridization using fluorescence depolarization spectroscopy.
Analytical biochemistry 2005;340(2):369-72.
2005: Higuchi Maiko; Yamayoshi Asako; Kobori Akio; Yamaoka Tetsuji; Murakami Akira
Synthesis and properties of photo-reactive antisense oligonucleotides containing 2'-O-psoralen-conjugated adenosine.
Nucleic acids symposium series (2004) 2005;(49):331-2.
2005: Sakamoto Takashi; Mahara Atsushi; Akio Kobori; Yamaoka Tetsuji; Murakami Akira
Luminescence anisotropy-based detection of nucleic acids and proteins using long-lifetime Ru(II) complex as a luminescent label.
Nucleic acids symposium series (2004) 2005;(49):203-4.
2005: Iwase Reiko; Fukui Udai; Kobori Akio; Yamaoka Tetsuji; Murakami Akira
Synthesis of antisense oligonucleotides containing a photocleavable protecting group on a guanine base and their photoinduced duplex formation.
Nucleic acids symposium series (2004) 2005;(49):151-2.
2004: Sakamoto Takashi; Mahara Atsushi; Munaka Tatsuya; Yamagata Koich; Iwase Reiko; Yamaoka Tetsuji; Murakami Akira
Time-resolved luminescence anisotropy-based detection of immunoglobulin G using long-lifetime Ru(II) complex-labeled protein A.
Analytical biochemistry 2004;329(1):142-4.
2004: Shimada Naohiko; Mahara Atsushi; Sakamoto Takashi; Yamaoka Tetsuji; Murakami Akira
Transcriptome analysis using fluorescence-labeled oligonucleotide.
Nucleic acids symposium series (2004) 2004;(48):301-2.
2004: Hashimoto Tomoko; Murakami Akira; Yamaoka Tetsuji
An enhanced site-specific transcription efficiency of DNA/polypeptide-vector polyplexes.
Nucleic acids symposium series (2004) 2004;(48):235-6.
2004: Iwase Reiko; Namie Yuji; Yamaoka Tetsuji; Murakami Akira
Synthesis and properties of fluorescent-labeled oligonucleotides containing amide-linked dinucleoside with pyrene.
Nucleic acids symposium series (2004) 2004;(48):75-6.
2003: Mahara Atsushi; Iwase Reiko; Sakamoto Takashi; Yamaoka Tetsuji; Yamana Kazushige; Murakami Akira
Detection of acceptor sites for antisense oligonucleotides on native folded RNA by fluorescence spectroscopy.
Bioorganic & medicinal chemistry 2003;11(13):2783-90.
2003: Yamayoshi Asako; Iwase Reiko; Yamaoka Tetsuji; Murakami Akira
Psoralen-conjugated oligonucleotide with hairpin structure as a novel photo-sensitive antisense molecule.
Chemical communications (Cambridge, England) 2003;(12):1370-1.
2003: Yamayoshi Asako; Kato Kiyoko; Iwase Reiko; Yamaoka Tetsuji; Wake Norio; Murakami Akira
Photodynamic antisense therapy: regulation of cervical carcinoma cells by psoralen-conjugated oligonucleotides.
Nucleic acids research. Supplement (2001) 2003;(3):75-6.
2003: Mahara Atsushi; Sakamoto Takashi; Munaka Tatsuya; Iwase Reiko; Yamaoka Tetsuji; Murakami Akira
Detection of acceptor sites for antisense oligonucleotides on native folded RNA by fluorescence-labeled oligonucleotide.
Nucleic acids research. Supplement (2001) 2003;(3):73-4.
2003: Iwase Reiko; Kitani Aki; Yamaoka Tetsuji; Murakami Akira
Synthesis of antisense oligonucleotides containing photocleavable protecting groups on the thymine bases and their photoinduced duplex formation.
Nucleic acids research. Supplement (2001) 2003;(3):61-2.
2002: Mahara Atsushi; Iwase Reiko; Sakamoto Takashi; Yamana Kazushige; Yamaoka Tetsuji; Murakami Akira
Bispyrene-conjugated 2'-O-methyloligonucleotide as a highly specific RNA-recognition probe.
Angewandte Chemie (International ed. in English) 2002;41(19):3648-50, 3518.
2002: Shimada Naohiko; Oniwa Keiichiro; Iwase Reiko; Yamaoka Tetsuji; Murakami Akira
Selection of RNA-binding peptides containing Arg-rich motif.
Nucleic acids research. Supplement (2001) 2002;(2):281-2.
2001: Murakami A
Making sense of antisense.
Trends in molecular medicine 2001;7(10):430-1.
2001: Murakami A; Yamayoshi A; Iwase R; Nishida J; Yamaoka T; Wake N
Photodynamic antisense regulation of human cervical carcinoma cell growth using psoralen-conjugated oligo(nucleoside phosphorothioate).
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;13(1):25-34.
2001: Kimura T; Yamaoka T; Iwase R; Murakami A
Structure/function relationship in the polyplexes containing cationic polypeptides for gene delivery.
Nucleic acids research. Supplement (2001) 2001;(1):203-4.
2001: Sakamoto T; Mahara A; Iwase R; Yamaoka T; Murakami A
Study on structure of ribosomal RNA by time-resolved luminescence anisotropy analysis.
Nucleic acids research. Supplement (2001) 2001;(1):143-4.
2000: Kimura T; Yamaoka T; Iwase R; Murakami A
Effect of serine residue on the effectiveness of cationic polypeptide-based gene delivery.
Nucleic acids symposium series 2000;(44):299-300.
2000: Mahara A; Iwase R; Yamana K; Yamaoka T; Murakami A
Characterization of RNA structure by bis-pyrene-labeled 2'-O-methyloligonucleotides.
Nucleic acids symposium series 2000;(44):199-200.
1999: Iwase R; Yamayoshi A; Nishida J; Yamaoka T; Wake N; Murakami A
Photodynamic antisense regulation using psoralen-conjugated oligo(nucleoside phosphorothioate)s (I). Growth regulation of cervical carcinoma cells.
Nucleic acids symposium series 1999;(42):223-4.
1999: Iwase R; Mahara A; Yamana K; Yamaoka T; Murakami A
Study on RNA structure by pyrene-labeled 2'-O-methyloligoribonucleotides.
Nucleic acids symposium series 1999;(42):115-6.
1998: Murakami A; Yamaoka T; Iwase R
[Recent development of nucleic acid drug]
Nippon rinsho. Japanese journal of clinical medicine 1998;56(3):563-72.
1998: Tamura Y; Miyoshi H; Yokota T; Makino K; Murakami A
Preparation of stereoregulated antisense oligodeoxyribonucleoside phosphorothioate and interaction with its complementary DNA and RNA.
Nucleosides & nucleotides 1998;17(1-3):269-82.
1997: Iwase R; Tsuchida H; Yamaoka T; Yamana K; Murakami A
Study of RNA structure by pyrene-labeled oligonucleotides.
Nucleic acids symposium series 1997;(37):205-6.
1997: Iwase R; Namba M; Yamaoka T; Murakami A
Gene regulation by decoy approach (I): synthesis and properties of photo-crosslinked oligonucleotides.
Nucleic acids symposium series 1997;(37):203-4.
1995: Murakami A; Yoshimoto A; Furumoto A; Namba M; Yamaoka T
Mechanism of antisense effect studied by functionalized oligonucleotides.
Nucleic acids symposium series 1995;(34):229-30.
1994: Murakami A; Tamura Y; Wada H; Makino K
Separation and characterization of diastereoisomers of antisense oligodeoxyribonucleoside phosphorothioates.
Analytical biochemistry 1994;223(2):285-90.
1993: Murakami A; Mukae M; Nagahara S; Konishi Y; Ide H; Makino K
Oligonucleotides site-specifically spin-labeled at 5'-terminal or internucleotide linkage and their use in gene analyses.
Free radical research communications 1993;19 Suppl 1():S117-28.
1993: Makino K; Nagahara S; Konishi Y; Mukae M; Ide H; Murakami A
Detection of specific base sequences in solution using DNA probes labeled with d- and/or 15N-substituted spin-labels.
Free radical research communications 1993;19 Suppl 1():S109-16.
1993: Murakami A; Tamura Y; Takeguchi S; Miyoshi H; Morii T; Maekawa T; Abe T; Makino K
Mechanistic aspects of the interaction of antisense DNA.
Nucleic acids symposium series 1993;(29):21-2.
1993: Makino K; Nishi M; Suzuki T; Ohsumi S; Morii T; Ide H; Murakami A
Loop-like structure of dGTTG in solution.
Nucleic acids symposium series 1993;(29):191-3.
1992: Ide H; Hagi A; Ohsumi S; Murakami A; Makino K
Monomer-dimer equilibrium of nitroso-aromatic spin trap 3,5-dibromo-4-nitrosobenzenesulfonic acid, sodium salt (DBNBS), in aqueous solution.
Biochemistry international 1992;27(3):367-72.
1992: Morii T; Shimomura M; Saito I; Ide H; Murakami A; Makino K
Sequence-specific DNA recognition by basic peptides.
Nucleic acids symposium series 1992;(27):177-8.
1992: Murakami A; Suzuki T; Tamura Y; Nishi M; Morii T; Ide H; Makino K
NMR studies on solution structure of single-stranded oligonucleotides causing line broadening.
Nucleic acids symposium series 1992;(27):55-6.
1992: Ide H; Murayama H; Murakami A; Morii T; Makino K
Effects of base damages on DNA replication--mechanism of preferential purine nucleotide insertion opposite abasic site in template DNA.
Nucleic acids symposium series 1992;(27):167-8.
1992: Murakami A; Tamura Y; Nishi M; Morii T; Ide H; Makino K
Separation and characterization of diastereoisomeric oligonucleotide.
Nucleic acids symposium series 1992;(27):137-8.
1992: Murakami A; Otoi K; Fujimura N; Morii T; Ide H; Makino K
Syntheses and properties of fluorescent labeled oligonucleotides containing deoxyethenoadenosine at 5' end.
Nucleic acids symposium series 1992;(27):125-6.
1992: Murakami A; Nagahara S; Uematsu H; Otoi K; Haruna T; Ide H; Makino K
Interaction of antisense DNA with nucleic acids/proteins.
Nucleic acids symposium series 1992;(27):123-4.
1991: Murakami A; Nakaura M; Nakatsuji Y; Nagahara S; Tran-Cong Q; Makino K
Fluorescent-labeled oligonucleotide probes: detection of hybrid formation in solution by fluorescence polarization spectroscopy.
Nucleic acids research 1991;19(15):4097-102.
1991: Makino K; Nishi M; Suzuki T; Tamura Y; Ide H; Murakami A
Unusual signal broadening in NMR of oligonucleotides.
Nucleic acids symposium series 1991;(25):179-80.
1991: Ide H; Kimura Y; Murakami A; Wallace S S; Makino K
Effects of base damages on DNA replication.
Nucleic acids symposium series 1991;(25):161-2.
1991: Murakami A; Uematsu H; Tamura Y; Nagahara S; Ide H; Makino K
Characterization of antisense DNA derivatives having stereoisomeric linkages.
Nucleic acids symposium series 1991;(25):133-4.
1990: Makino K; Hagiwara T; Hagi A; Nishi M; Murakami A
Cautionary note for DMPO spin trapping in the presence of iron ion.
Biochemical and biophysical research communications 1990;172(3):1073-80.
1990: Makino K; Hagiwara T; Imaishi H; Nishi M; Fujii S; Ohya H; Murakami A
DMPO spin trapping in the presence of Fe ion.
Free radical research communications 1990;9(3-6):233-40.
1990: Murakami A; Nagahara S; Nakaura M; Uematsu H; Mukae M; Makino K
Structural analysis of nucleic acids by labeled oligonucleotides.
Nucleic acids symposium series 1990;(22):27-8.
1989: Murakami A; Nagahara S; Takeuchi T; Makino K
ESR behaviour of spin-labelled oligoDNAs.
Nucleic acids symposium series 1989;(21):89-90.
1989: Makino K; Murakami A; Nagahara S; Nakatsuji Y; Takeuchi T
A study on spin-labelled oligonucleotide synthesis and its electron spin resonance behavior in solution.
Free radical research communications 1989;6(5):311-6.
1989: Makino K; Imaishi H; Morinishi S; Hagiwara T; Takeuchi T; Murakami A; Nishi M
An artifact in the ESR spectrum obtained by spin trapping with DMPO.
Free radical research communications 1989;6(1):19-28.

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Akira Murakami

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