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Hideki Murakami

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Chemicals & Drugs

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3T3 Cells

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Shinya Akatsuka; Eri Arai; Okio Hino; Masashi Izumiya; Li Jiang; Yae Kanai; Yu-Ting Liu; Hideki Murakami; Hirotaka Nagai; Hitoshi Nakagama; Masako Ochiai; Hiroki Ohara; Yasumasa Okazaki; Yoshitaka Sekido; Takashi Takahashi; Koichiro Abe; Yoriko Yamashita; Shinya Toyokuni
Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer.
Atsushi Enomoto; Hideki Murakami; Naoya Asai; Nobuhiro Morone; Takashi Watanabe; Kumi Kawai; Yoshiki Murakumo; Jiro Usukura; Kozo Kaibuchi; Masahide Takahashi
Akt/PKB regulates actin organization and cell motility via Girdin/APE.
Makoto Sugiura; Eisuke Sato; Tsutomu Nakashima; Junko Sugiura; Atsushi Furuhashi; Takahiko Yoshino; Atsuo Nakayama; Naoyoshi Mori; Hideki Murakami; Shinji Naganawa
Long-term follow-up in patients with Pendred syndrome: vestibular, auditory and other phenotypes.

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All Publications

2012: Shinya Akatsuka; Eri Arai; Okio Hino; Masashi Izumiya; Li Jiang; Yae Kanai; Yu-Ting Liu; Hideki Murakami; Hirotaka Nagai; Hitoshi Nakagama; Masako Ochiai; Hiroki Ohara; Yasumasa Okazaki; Yoshitaka Sekido; Takashi Takahashi; Koichiro Abe; Yoriko Yamashita; Shinya Toyokuni
Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer.
PloS one 2012;7(8):e43403.
2005: Atsushi Enomoto; Hideki Murakami; Naoya Asai; Nobuhiro Morone; Takashi Watanabe; Kumi Kawai; Yoshiki Murakumo; Jiro Usukura; Kozo Kaibuchi; Masahide Takahashi
Akt/PKB regulates actin organization and cell motility via Girdin/APE.
Developmental cell 2005;9(3):389-402.
2005: Makoto Sugiura; Eisuke Sato; Tsutomu Nakashima; Junko Sugiura; Atsushi Furuhashi; Takahiko Yoshino; Atsuo Nakayama; Naoyoshi Mori; Hideki Murakami; Shinji Naganawa
Long-term follow-up in patients with Pendred syndrome: vestibular, auditory and other phenotypes.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2005;262(9):737-43.
2005: Tetsuo Matsuura; Yohei Shimono; Kumi Kawai; Hideki Murakami; Takeshi Urano; Yasumasa Niwa; Hidemi Goto; Masahide Takahashi
PIAS proteins are involved in the SUMO-1 modification, intracellular translocation and transcriptional repressive activity of RET finger protein.
Experimental cell research 2005;308(1):65-77.
2004: Kengo Maeda; Hideki Murakami; Reiko Yoshida; Masatoshi Ichihara; Akihiro Abe; Makoto Hirai; Toyoaki Murohara; Masahide Takahashi
Biochemical and biological responses induced by coupling of Gab1 to phosphatidylinositol 3-kinase in RET-expressing cells.
Biochemical and biophysical research communications 2004;323(1):345-54.
2003: Yohei Shimono; Hideki Murakami; Kumi Kawai; Paul A Wade; Kaoru Shimokata; Masahide Takahashi
Mi-2 beta associates with BRG1 and RET finger protein at the distinct regions with transcriptional activating and repressing abilities.
The Journal of biological chemistry 2003;278(51):51638-45.
2003: Atsuo Nakayama; Hideki Murakami; Naomi Maeyama; Norie Yamashiro; Ayako Sakakibara; Naoyoshi Mori; Masahide Takahashi
Role for RFX transcription factors in non-neuronal cell-specific inactivation of the microtubule-associated protein MAP1A promoter.
The Journal of biological chemistry 2003;278(1):233-40.
2002: Hideki Murakami; Yumiko Yamamura; Yohei Shimono; Kumi Kawai; Kei Kurokawa; Masahide Takahashi
Role of Dok1 in cell signaling mediated by RET tyrosine kinase.
The Journal of biological chemistry 2002;277(36):32781-90.
2002: Tsuyoshi Watanabe; Masatoshi Ichihara; Mizuo Hashimoto; Keiko Shimono; Yoshie Shimoyama; Tetsuro Nagasaka; Yoshiki Murakumo; Hideki Murakami; Hideshi Sugiura; Hisashi Iwata; Naoki Ishiguro; Masahide Takahashi
Characterization of gene expression induced by RET with MEN2A or MEN2B mutation.
The American journal of pathology 2002;161(1):249-56.
2002: Naoko Iwahashi; Hideki Murakami; Yuji Nimura; Masahide Takahashi
Activation of RET tyrosine kinase regulates interleukin-8 production by multiple signaling pathways.
Biochemical and biophysical research communications 2002;294(3):642-9.
2001: Eisuke Sato; Tsutomu Nakashima; Yoshitaka Miura; Atsushi Furuhashi; Atsuo Nakayama; Naoyoshi Mori; Hideki Murakami; Shinji Naganawa; M Tadokoro
Phenotypes associated with replacement of His by Arg in the Pendred syndrome gene.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(6):697-703.
2001: Toshihide Iwashita; Kei Kurokawa; Shanlou Qiao; Hideki Murakami; Naoya Asai; Kumi Kawai; Mizuo Hashimoto; Tsuyoshi Watanabe; Masatoshi Ichihara; Masahide Takahashi
Functional analysis of RET with Hirschsprung mutations affecting its kinase domain.
Gastroenterology 2001;121(1):24-33.
2001: Kei Kurokawa; Toshihide Iwashita; Hideki Murakami; Hideo Hayashi; Kumi Kawai; Masahide Takahashi
Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction.
Oncogene 2001;20(16):1929-38.
2000: Yohei Shimono; Hideki Murakami; Yoshinori Hasegawa; Masahide Takahashi
RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions.
The Journal of biological chemistry 2000;275(50):39411-9.
2000: Kumi Kawai; Toshihide Iwashita; Hideki Murakami; Noriko Hiraiwa; Atsushi Yoshiki; Moriaki Kusakabe; Koichiro Ono; K Iida; A Nakayama; Masahide Takahashi
Tissue-specific carcinogenesis in transgenic mice expressing the RET proto-oncogene with a multiple endocrine neoplasia type 2A mutation.
Cancer research 2000;60(18):5254-60.
2000: Hideo Hayashi; Masatoshi Ichihara; Toshihide Iwashita; Hideki Murakami; Yohei Shimono; Kumi Kawai; Kei Kurokawa; Yoshiki Murakumo; Tsuneo Imai; Hiroomi Funahashi; Akimasa Nakao; Masahide Takahashi
Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor.
Oncogene 2000;19(39):4469-75.
2000: Toshihide Iwashita; Hideki Murakami; Kei Kurokawa; Kumi Kawai; A Miyauchi; H Futami; Shanlou Qiao; Masatoshi Ichihara; Masahide Takahashi
A two-hit model for development of multiple endocrine neoplasia type 2B by RET mutations.
Biochemical and biophysical research communications 2000;268(3):804-8.
1999: Y Ishiguro; Toshihide Iwashita; Hideki Murakami; Naoya Asai; K Iida; H Goto; Tetsuo Hayakawa; Masahide Takahashi
The role of amino acids surrounding tyrosine 1062 in ret in specific binding of the shc phosphotyrosine-binding domain.
Endocrinology 1999;140(9):3992-8.
1999: Hideki Murakami; Toshihide Iwashita; Naoya Asai; Yohei Shimono; Y Iwata; Kumi Kawai; Masahide Takahashi
Enhanced phosphatidylinositol 3-kinase activity and high phosphorylation state of its downstream signalling molecules mediated by ret with the MEN 2B mutation.
Biochemical and biophysical research communications 1999;262(1):68-75.
1999: Y Iwata; A Nakayama; Hideki Murakami; K Iida; Toshihide Iwashita; Naoya Asai; Masahide Takahashi
Characterization of the promoter region of the human RFP gene.
Biochemical and biophysical research communications 1999;261(2):381-4.
1999: Toshihide Iwashita; Masashi Kato; Hideki Murakami; Naoya Asai; Y Ishiguro; Shosuke Ito; Y Iwata; Kumi Kawai; M Asai; Kei Kurokawa; H Kajita; Masahide Takahashi
Biological and biochemical properties of Ret with kinase domain mutations identified in multiple endocrine neoplasia type 2B and familial medullary thyroid carcinoma.
Oncogene 1999;18(26):3919-22.
1999: Hideki Murakami; Toshihide Iwashita; Naoya Asai; Y Iwata; S Narumiya; Masahide Takahashi
Rho-dependent and -independent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130Cas mediated by Ret kinase.
Oncogene 1999;18(11):1975-82.
1999: Naoya Asai; Toshihide Iwashita; Hideki Murakami; H Takanari; K Ohmori; Masatoshi Ichihara; Masahide Takahashi
Mechanism of Ret activation by a mutation at aspartic acid 631 identified in sporadic pheochromocytoma.
Biochemical and biophysical research communications 1999;255(3):587-90.
1999: M Asai; Masashi Kato; Naoya Asai; Toshihide Iwashita; Hideki Murakami; Kumi Kawai; Izumi Nakashima; Masahide Takahashi
Differential regulation of MMP-9 and TIMP-2 expression in malignant melanoma developed in metallothionein/RET transgenic mice.
Japanese journal of cancer research : Gann 1999;90(1):86-92.
1998: Masahide Takahashi; Naoya Asai; Toshihide Iwashita; Hideki Murakami; Shosuke Ito
Molecular mechanisms of development of multiple endocrine neoplasia 2 by RET mutations.
Journal of internal medicine 1998;243(6):509-13.
1998: C Nozaki; Naoya Asai; Hideki Murakami; Toshihide Iwashita; Y Iwata; Keizo Horibe; RD Klein; Arnon Rosenthal; Masahide Takahashi
Calcium-dependent Ret activation by GDNF and neurturin.
Oncogene 1998;16(3):293-9.
1998: Masahide Takahashi; Naoya Asai; Toshihide Iwashita; Hideki Murakami; Shosuke Ito
Mechanisms of development of multiple endocrine neoplasia type 2 and Hirschsprung's disease by ret mutations.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;154():229-36.
1997: Mikinao Ohiwa; Hideki Murakami; Toshihide Iwashita; Naoya Asai; Y Iwata; Tsuneo Imai; Hiroomi Funahashi; Hiroyuki Takagi; Masahide Takahashi
Characterization of Ret-Shc-Grb2 complex induced by GDNF, MEN 2A, and MEN 2B mutations.
Biochemical and biophysical research communications 1997;237(3):747-51.
1997: Shosuke Ito; Toshihide Iwashita; Naoya Asai; Hideki Murakami; Y Iwata; Gen Sobue; Masahide Takahashi
Biological properties of Ret with cysteine mutations correlate with multiple endocrine neoplasia type 2A, familial medullary thyroid carcinoma, and Hirschsprung's disease phenotype.
Cancer research 1997;57(14):2870-2.
1996: Toshihide Iwashita; Hideki Murakami; Naoya Asai; M Takahashi
Mechanism of ret dysfunction by Hirschsprung mutations affecting its extracellular domain.
Human molecular genetics 1996;5(10):1577-80.
1996: N Hasegawa; Toshihide Iwashita; Naoya Asai; Hideki Murakami; Y Iwata; T Isomura; H Goto; T Hayakawa; M Takahashi
A RING finger motif regulates transforming activity of the rfp/ret fusion gene.
Biochemical and biophysical research communications 1996;225(2):627-31.
1996: Naoya Asai; Hideki Murakami; Toshihide Iwashita; M Takahashi
A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins.
The Journal of biological chemistry 1996;271(30):17644-9.
1996: Toshihide Iwashita; Naoya Asai; Hideki Murakami; M Matsuyama; M Takahashi
Identification of tyrosine residues that are essential for transforming activity of the ret proto-oncogene with MEN2A or MEN2B mutation.
Oncogene 1996;12(3):481-7.