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Hiroaki Murata

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Yasushi Sawai; Yoshiro Tsuji; Eishi Ashihara; Naoyuki Horie; Motoyuki Horii; Kazutaka Koto; Toshikazu Kubo; Taira Maekawa; Takaaki Matsui; Hiroaki Murata; Shinji Fushiki
Effectiveness of sulforaphane as a radiosensitizer for murine osteosarcoma cells.
Kazutaka Koto; Toshikazu Kubo; Taira Maekawa; Takaaki Matsui; Hiroaki Murata; Kazuteru Ryu; Yasushi Sawai; Eishi Ashihara; Naoyuki Horie; Shinya Kimura; Shinji Fushiki
Zoledronic acid significantly enhances radiation‑induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling.
Kazutaka Koto; Naoyuki Horie; Toshihiro Ishida; Eiichi Konishi; Hiroaki Murata; Shinichiro Nakamura; Kazuteru Ryu; Tomoya Sakabe; Toshikazu Kubo
Chondrosarcoma from the sternum: reconstruction with titanium mesh and a transverse rectus abdominis myocutaneous flap after subtotal sternal excision.

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2013: Yasushi Sawai; Yoshiro Tsuji; Eishi Ashihara; Naoyuki Horie; Motoyuki Horii; Kazutaka Koto; Toshikazu Kubo; Taira Maekawa; Takaaki Matsui; Hiroaki Murata; Shinji Fushiki
Effectiveness of sulforaphane as a radiosensitizer for murine osteosarcoma cells.
Oncology reports 2013;29(3):941-5.
2013: Kazutaka Koto; Toshikazu Kubo; Taira Maekawa; Takaaki Matsui; Hiroaki Murata; Kazuteru Ryu; Yasushi Sawai; Eishi Ashihara; Naoyuki Horie; Shinya Kimura; Shinji Fushiki
Zoledronic acid significantly enhances radiation‑induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling.
International journal of oncology 2013;42(2):525-34.
2012: Kazutaka Koto; Naoyuki Horie; Toshihiro Ishida; Eiichi Konishi; Hiroaki Murata; Shinichiro Nakamura; Kazuteru Ryu; Tomoya Sakabe; Toshikazu Kubo
Chondrosarcoma from the sternum: reconstruction with titanium mesh and a transverse rectus abdominis myocutaneous flap after subtotal sternal excision.
Medical science monitor : international medical journal of experimental and clinical research 2012;18(10):CS77-81.
2012: Yasushi Sawai; Taira Maekawa; Takaaki Matsui; Hiroaki Murata; Eishi Ashihara; Shinji Fushiki; Naoyuki Horie; Kazutaka Koto; Toshikazu Kubo
Effects of low-intensity pulsed ultrasound on osteosarcoma and cancer cells.
Oncology reports 2012;28(2):481-6.
2012: Katsuyuki Kusuzaki; Eishi Ashihara; Nicola Baldini; Stefano Fais; Shigekuni Hosogi; Takao Matsubara; Akihiko Matsumine; Hiroaki Murata; Tomoki Nakamura; Haruhiko Satonaka; Akihiro Sudo; Atsumasa Uchida; Yoshinori Marunaka
Translational research of photodynamic therapy with acridine orange which targets cancer acidity.
Current pharmaceutical design 2012;18(10):1414-20.
2011: Tomoya Sakabe; Hiroaki Murata; Eiichi Konishi; Kazutaka Koto; Naoyuki Horie; Takaaki Matsui; Yasushi Sawai; Hideya Yamazaki; Tsutomu V Kagiya; Toshikazu Kubo
High Efficacy of Preoperative Low-Dose Radiotherapy with Sanazole (AK-2123) for Extraskeletal Ewing's Sarcoma: A Case Report.
Sarcoma 2011;2011():.
2010: Taka-Aki Matsui; Hiroaki Murata; Yoshihiro Sowa; Tomoya Sakabe; Kazutaka Koto; Naoyuki Horie; Yoshiro Tsuji; Toshiyuki Sakai; Toshikazu Kubo
A novel MEK1/2 inhibitor induces G1/S cell cycle arrest in human fibrosarcoma cells.
Oncology reports 2010;24(2):329-33.
2010: Kazuteru Ryu; Hiroaki Murata; Kazutaka Koto; Naoyuki Horie; Takaaki Matsui; Yasunori Nishigaki; Tomoya Sakabe; Hideyuki Takeshita; Megumi Itoi; Shinya Kimura; Eishi Ashihara; Taira Maekawa; Shinji Fushiki; Toshikazu Kubo
Combined effects of bisphosphonate and radiation on osteosarcoma cells.
Anticancer research 2010;30(7):2713-20.
2010: Kazutaka Koto; Hiroaki Murata; Shinya Kimura; Naoyuki Horie; Takaaki Matsui; Yasunori Nishigaki; Kazuteru Ryu; Tomoya Sakabe; Megumi Itoi; Eishi Ashihara; Taira Maekawa; Shinji Fushiki; Toshikazu Kubo
Zoledronic acid inhibits proliferation of human fibrosarcoma cells with induction of apoptosis, and shows combined effects with other anticancer agents.
Oncology reports 2010;24(1):233-9.
2009: Kazutaka Koto; Naoyuki Horie; Shinya Kimura; Hiroaki Murata; Tomoya Sakabe; Takaaki Matsui; Motonobu Watanabe; Souichi Adachi; Taira Maekawa; Shinji Fushiki; Toshikazu Kubo
Clinically relevant dose of zoledronic acid inhibits spontaneous lung metastasis in a murine osteosarcoma model.
Cancer letters 2009;274(2):271-8.
2008: Tomoya Sakabe; Hiroaki Murata; Eiichi Konishi; Hideyuki Takeshita; Hideki Ueda; Takaaki Matsui; Naoyuki Horie; Akio Yanagisawa; Toshikazu Kubo
Evaluation of clinical outcomes and prognostic factors for synovial sarcoma arising from the extremities.
Medical science monitor : international medical journal of experimental and clinical research 2008;14(6):CR305-310.
2008: Eiichi Konishi; Takako Okubo; Megumi Itoi; Yasukazu Katsumi; Hiroaki Murata; Akio Yanagisawa
Chondroblastoma of trapezium with metacarpal involvement.
Orthopedics 2008;31(4):395.
2008: Hiroaki Murata; Naoyuki Horie; Takaaki Matsui; Takanori Akai; Hideki Ueda; Yasushi Oshima; Eiichi Konishi; Toshikazu Kubo
Clinical usefulness of thallium-201 scintigraphy and magnetic resonance imaging in the diagnosis of chondromyxoid fibroma.
Annals of nuclear medicine 2008;22(3):221-4.
2007: Tomoya Sakabe; Hiroaki Murata; Yukiko Tokumoto; Kazutaka Koto; Takaaki Matsui; Naoyuki Horie; Toshikazu Kubo
Soft tissue mass of the thigh: presentation, diagnosis and discussion.
Skeletal radiology 2007;36(12):1177-1180.
2007: Taka-Aki Matsui; Hiroaki Murata; Tomoya Sakabe; Yoshihiro Sowa; Naoyuki Horie; Ryoko Nakanishi; Toshiyuki Sakai; Toshikazu Kubo
Sulforaphane induces cell cycle arrest and apoptosis in murine osteosarcoma cells in vitro and inhibits tumor growth in vivo.
Oncology reports 2007;18(5):1263-8.
2007: Taka-aki Matsui; Yoshihiro Sowa; Hiroaki Murata; Koichi Takagi; Ryoko Nakanishi; Shunji Aoki; Masayuki Yoshikawa; Motomasa Kobayashi; Tomoya Sakabe; Toshikazu Kubo; Toshiyuki Sakai
The plant alkaloid cryptolepine induces p21WAF1/CIP1 and cell cycle arrest in a human osteosarcoma cell line.
International journal of oncology 2007;31(4):915-22.
2007: Hiroaki Murata; Takaai Matsui; Naoyuki Horie; Tomoya Sakabe; Eiichi Konishi; Toshikazu Kubo
Angioleiomyoma with calcification of the heel: report of two cases.
Foot & ankle international. / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society 2007;28(9):1021-5.
2007: N Horie; Hiroaki Murata; S Kimura; Hideyuki Takeshita; T Sakabe; T Matsui; T Maekawa; T Kubo; S Fushiki
Combined effects of a third-generation bisphosphonate, zoledronic acid with other anticancer agents against murine osteosarcoma.
British journal of cancer 2007;96(2):255-61.
2006: M Hirata; Hiroaki Murata; Hideyuki Takeshita; T Sakabe; Y Tsuji; T Kubo
Use of purified beta-tricalcium phosphate for filling defects after curettage of benign bone tumours.
International orthopaedics 2006;30(6):510-3.
2006: Taka-aki Matsui; Yoshihiro Sowa; Tatsushi Yoshida; Hiroaki Murata; Mano Horinaka; Miki Wakada; Ryoko Nakanishi; Tomoya Sakabe; Toshikazu Kubo; Toshiyuki Sakai
Sulforaphane enhances TRAIL-induced apoptosis through the induction of DR5 expression in human osteosarcoma cells.
Carcinogenesis 2006;27(9):1768-77.
2006: Naoyuki Horie; Hiroaki Murata; Yasunori Nishigaki; Takaaki Matsui; Hidekazu Segawa; Masaki Nogawa; Takeshi Yuasa; Shinya Kimura; Taira Maekawa; Shinji Fushiki; Toshikazu Kubo
The third-generation bisphosphonates inhibit proliferation of murine osteosarcoma cells with induction of apoptosis.
Cancer letters 2006;238(1):111-8.
2006: Tomoya Sakabe; Ryo Imai; Hiroaki Murata; Mikihiro Fujioka; Noriyuki Iwamoto; Toshihiko Ono; Toshikazu Kubo
Life expectancy and functional prognosis after femoral neck fractures in hemodialysis patients.
Journal of orthopaedic trauma 2006;20(5):330-6.
2005: Hideki Ueda; Hiroaki Murata; Hideyuki Takeshita; Ginjiro Minami; Shin Hashiguchi; Toshikazu Kubo
Unfiltered xenon light is useful for photodynamic therapy with acridine orange.
Anticancer research 2005;25(6B):3979-83.
2002: Shin Hashiguchi; Katsuyuki Kusuzaki; Hiroaki Murata; Hideyuki Takeshita; Mitsuoki Hashiba; Tsunehiko Nishimura; Tsukasa Ashihara; Yasusuke Hirasawa
Acridine orange excited by low-dose radiation has a strong cytocidal effect on mouse osteosarcoma.
Oncology 2002;62(1):85-93.
2001: Katsuyuki Kusuzaki; S Sugimoto; Hideyuki Takeshita; Hiroaki Murata; S Hashiguchi; T Nozaki; K Emoto; Tsukasa Ashihara; Yasusuke Hirasawa
DNA cytofluorometric analysis of chondrocytes in human articular cartilages under normal aging or arthritic conditions.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(7):664-70.
2001: T Nozaki; Katsuyuki Kusuzaki; H Takeshita; S Nakamura; S Hashiguchi; Hiroaki Murata; Y Hirasawa
Effectiveness of activated vitamin D3 on improving prognosis of osteosarcoma patients.
Oncology reports 2001;8(2):321-4.
2001: Katsuyuki Kusuzaki; Hideyuki Takeshita; Hiroaki Murata; Shin Hashiguchi; T Nozaki; K Emoto; Tsukasa Ashihara; Yasusuke Hirasawa
Acridine orange induces binucleation in chondrocytes.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(2):147-51.
2001: S Nakamura; Katsuyuki Kusuzaki; Hiroaki Murata; Hideyuki Takeshita; M Hirata; Shin Hashiguchi; Yasusuke Hirasawa
Ceramic endoprosthesis for aggressive giant cell tumors near the knee: eight cases followed for more than 10 years.
International orthopaedics 2001;25(2):104-6.
2000: Katsuyuki Kusuzaki; N Kageyama; H Shinjo; Hideyuki Takeshita; Hiroaki Murata; Shin Hashiguchi; Tsukasa Ashihara; Yasusuke Hirasawa
Development of bone canaliculi during bone repair.
Bone 2000;27(5):655-9.
2000: Hiroaki Murata; Katsuyuki Kusuzaki; Hideyuki Takeshita; M Hirata; Shin Hashiguchi; K Emoto; Tsukasa Ashihara; Yasusuke Hirasawa
Assessment of chemosensitivity in patients with malignant bone and soft tissue tumors using thallium-201 scintigraphy and doxorubicin binding assay.
Anticancer research 2000;20(5C):3967-70.
2000: Hiroaki Murata; Katsuyuki Kusuzaki; M Hirata; Shin Hashiguchi; Yasusuke Hirasawa
Extraabdominal desmoid tumor with dissemination detected by thallium-201 scintigraphy.
Anticancer research 2000;20(5C):3963-6.
2000: Katsuyuki Kusuzaki; H Shinjo; Hiroaki Murata; Hideyuki Takeshita; Shin Hashiguchi; T Nozaki; K Emoto; Tsukasa Ashihara; Yasusuke Hirasawa
Relationship between doxorubicin binding ability and tumor volume decrease after chemotherapy in adult malignant soft tissue tumors in the extremities.
Anticancer research 2000;20(5C):3813-6.
2000: Katsuyuki Kusuzaki; K Emoto; Hiroaki Murata; K Katsura; H Sugihara; Y Tsuchihashi; Yasusuke Hirasawa
Nerve contact with muscle component in neuromuscular hamartoma.
Anticancer research 2000;20(5C):3807-11.
2000: Katsuyuki Kusuzaki; T Suginoshita; Ginjiro Minami; K Aomori; Hideyuki Takeshita; Hiroaki Murata; Shin Hashiguchi; Tsukasa Ashihara; Yasusuke Hirasawa
Fluorovisualization effect of acridine orange on mouse osteosarcoma.
Anticancer research 2000;20(5A):3019-24.
2000: Katsuyuki Kusuzaki; Hideyuki Takeshita; Hiroaki Murata; Shin Hashiguchi; T Nozaki; K Emoto; Tsukasa Ashihara; Yasusuke Hirasawa
Binuclear cells induced by acridine orange in giant cell tumor of bone.
Anticancer research 2000;20(5A):3013-7.
2000: Katsuyuki Kusuzaki; K Aomori; T Suginoshita; Ginjiro Minami; Hideyuki Takeshita; Hiroaki Murata; Shin Hashiguchi; Tsukasa Ashihara; Yasusuke Hirasawa
Total tumor cell elimination with minimum damage to normal tissues in musculoskeletal sarcomas following photodynamic therapy with acridine orange.
Oncology 2000;59(2):174-80.
2000: Katsuyuki Kusuzaki; Hideyuki Takeshita; Hiroaki Murata; Shin Hashiguchi; T Nozaki; K Emoto; Tsukasa Ashihara; Yasusuke Hirasawa
Relationship between binuclear and multinuclear cells in giant cell tumor of bone.
Anticancer research 2000;20(4):2463-7.
2000: Katsuyuki Kusuzaki; Ginjiro Minami; Hideyuki Takeshita; Hiroaki Murata; Shin Hashiguchi; T Nozaki; Tsukasa Ashihara; Yasusuke Hirasawa
Photodynamic inactivation with acridine orange on a multidrug-resistant mouse osteosarcoma cell line.
Japanese journal of cancer research : Gann 2000;91(4):439-45.
2000: Hideyuki Takeshita; Katsuyuki Kusuzaki; Hiroaki Murata; T Suginoshita; M Hirata; Shin Hashiguchi; Tsukasa Ashihara; M C Gebhardt; H J Mankin; Yasusuke Hirasawa
Osteoblastic differentiation and P-glycoprotein multidrug resistance in a murine osteosarcoma model.
British journal of cancer 2000;82(7):1327-31.
2000: Katsuyuki Kusuzaki; Hiroaki Murata; Hideyuki Takeshita; Shin Hashiguchi; T Nozaki; K Emoto; Tsukasa Ashihara; Yasusuke Hirasawa
Intracellular binding sites of acridine orange in living osteosarcoma cells.
Anticancer research 2000;20(2A):971-5.
2000: Katsuyuki Kusuzaki; Hideyuki Takeshita; Hiroaki Murata; M C Gebhardt; D S Springfield; H J Mankin; Tsukasa Ashihara; Yasusuke Hirasawa
Polyploidization induced by acridine orange in mouse osteosarcoma cells.
Anticancer research 2000;20(2A):965-70.
2000: S Nakamura; Katsuyuki Kusuzaki; Hiroaki Murata; Hideyuki Takeshita; M Hirata; Shin Hashiguchi; Yasusuke Hirasawa
More than 10 years of follow-up of two patients after total femur replacement for malignant bone tumor.
International orthopaedics 2000;24(3):176-8.
2000: T Suginoshita; Katsuyuki Kusuzaki; T Nagaoka; Hiroaki Murata; M Hirata; Shin Hashiguchi; Yasusuke Hirasawa
Case report: natural development of osteosarcoma from precancerous lesion.
Anticancer research 2000;20(1B):511-4.
1999: Hideyuki Takeshita; Katsuyuki Kusuzaki; Hiroaki Murata; S Nakamura; Tsukasa Ashihara; Yasusuke Hirasawa
Improving the cytometric detection of doxorubicin resistance in osteosarcoma cells by determining cellular doxorubicin/DNA ratio.
Anticancer research 1999;19(6B):5235-8.
1999: Katsuyuki Kusuzaki; M Hirata; Shin Hashiguchi; Hideyuki Takeshita; Hiroaki Murata; Tsukasa Ashihara; Yasusuke Hirasawa
Acquisition of multidrug resistance in osteosarcomas, analyzed by doxorubicin binding assay, and histologic response to chemotherapy.
Anticancer research 1999;19(6B):5159-62.
1999: Katsuyuki Kusuzaki; Hiroaki Murata; Hideyuki Takeshita; M Hirata; Shin Hashiguchi; Y Tsuji; S Nakamura; Tsukasa Ashihara; Yasusuke Hirasawa
Usefulness of cytofluorometric DNA ploidy analysis in distinguishing benign cartilaginous tumors from chondrosarcomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1999;12(9):863-72.
1999: Katsuyuki Kusuzaki; Hideyuki Takeshita; Hiroaki Murata; M Hirata; Shin Hashiguchi; Tsukasa Ashihara; Yasusuke Hirasawa
Prognostic value of DNA ploidy response to chemotherapy in human osteosarcomas.
Cancer letters 1999;141(1-2):131-8.
1999: Hiroaki Murata; Katsuyuki Kusuzaki; Yasusuke Hirasawa; Tsukasa Ashihara; T Abe; J Inazawa
Relationship between chromosomal aberrations by fluorescence in situ hybridization and DNA ploidy by cytofluorometry in osteosarcoma.
Cancer letters 1999;139(2):221-6.
1999: Katsuyuki Kusuzaki; M Hirata; Hideyuki Takeshita; Hiroaki Murata; Shin Hashiguchi; Tsukasa Ashihara; Yasusuke Hirasawa
Relationship between P-glycoprotein positivity, doxorubicin binding ability and histologic response to chemotherapy in osteosarcomas.
Cancer letters 1999;138(1-2):203-8.
1999: Katsuyuki Kusuzaki; Shin Hashiguchi; M Hirata; Hideyuki Takeshita; Hiroaki Murata; Tsukasa Ashihara; Yasusuke Hirasawa
Response of DNA ploidy to chemotherapy in primary and metastatic lesions in human osteosarcomas.
Cancer letters 1999;138(1-2):159-65.
1999: Katsuyuki Kusuzaki; Hideyuki Takeshita; Hiroaki Murata; M Hirata; Shin Hashiguchi; Tsukasa Ashihara; Yasusuke Hirasawa
Prognostic significance of DNA ploidy pattern in osteosarcomas in association with chemotherapy.
Cancer letters 1999;137(1):27-33.
1999: Hiroaki Murata; Katsuyuki Kusuzaki; Hideyuki Takeshita; M Hirata; Shin Hashiguchi; Tsukasa Ashihara; Yasusuke Hirasawa
Cytofluorometric DNA ploidy analysis in giant cell tumor of bone: histologic and prognostic value.
Cancer letters 1999;136(2):223-9.
1998: Katsuyuki Kusuzaki; H Shinjo; W Kim; S Nakamura; Hiroaki Murata; Yasusuke Hirasawa
Resection hip arthroplasty for malignant pelvic tumor. Outcome in 5 patients followed more than 2 years.
Acta orthopaedica Scandinavica 1998;69(6):617-21.
1998: Katsuyuki Kusuzaki; Hideyuki Takeshita; Hiroaki Murata; M Hirata; Shin Hashiguchi; Tsukasa Ashihara; Yasusuke Hirasawa
Relation between cellular doxorubicin binding ability to nuclear DNA and histologic response to preoperative chemotherapy in patients with osteosarcoma.
Cancer 1998;82(12):2343-9.
1998: Hideyuki Takeshita; Katsuyuki Kusuzaki; Y Tsuji; M Hirata; Shin Hashiguchi; S Nakamura; Hiroaki Murata; Tsukasa Ashihara; Yasusuke Hirasawa
Avoidance of doxorubicin resistance in osteosarcoma cells using a new quinoline derivative, MS-209.
Anticancer research 1998;18(2A):739-42.
1997: Hiroaki Murata; Katsuyuki Kusuzaki; Yasusuke Hirasawa; J Inazawa; T Abe; Tsukasa Ashihara
Ploidy analysis in paraffin-embedded malignant fibrous histiocytoma by DNA cytofluorometry and flourescence in situ hybridization.
Cancer letters 1997;118(1):123-8.