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Harald Murck

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Harald Murck
Ketamine, magnesium and major depression - From pharmacology to pathophysiology and back.
M Franklin; gaburro stefano; N Hlavacova; S Babic; Isabel Bermudez; Harald Murck; C Schmuckermair; Nicolas Singewald; D Jezova
Aldosterone increases earlier than corticosterone in new animal models of depression: is this an early marker?
Harald Murck; Petra Schüssler; Axel Steiger
Renin-angiotensin-aldosterone system: the forgotten stress hormone system: relationship to depression and sleep.

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All Publications

2013: Harald Murck
Ketamine, magnesium and major depression - From pharmacology to pathophysiology and back.
Journal of psychiatric research 2013;47(7):955-65.
2012: M Franklin; gaburro stefano; N Hlavacova; S Babic; Isabel Bermudez; Harald Murck; C Schmuckermair; Nicolas Singewald; D Jezova
Aldosterone increases earlier than corticosterone in new animal models of depression: is this an early marker?
Journal of psychiatric research 2012;46(11):1394-7.
2012: Harald Murck; Petra Schüssler; Axel Steiger
Renin-angiotensin-aldosterone system: the forgotten stress hormone system: relationship to depression and sleep.
Pharmacopsychiatry 2012;45(3):83-95.
2012: Natasa Hlavacova; Stanislav Babic; Marianne E Flynn; Harald Murck; Maria Ondrejcakova; Patricia K Poundstone; Paul D Wes; Daniela Jezova
Subchronic treatment with aldosterone induces depression-like behaviours and gene expression changes relevant to major depressive disorder.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2012;15(2):247-65.
2011: Heike E Künzel; Harald Murck; Günter K Stalla; Axel Steiger
Changes in the sleep electroencephalogram (EEG) during male to female transgender therapy.
Psychoneuroendocrinology 2011;36(7):1005-9.
2010: Marcus Mannel; Ulrike Kuhn; Ulrich Schmidt; Michael Ploch; Harald Murck
St. John's wort extract LI160 for the treatment of depression with atypical features - a double-blind, randomized, and placebo-controlled trial.
Journal of psychiatric research 2010;44(12):760-7.
2010: Mark A Stacy; Harald Murck; Kurt Kroenke
Responsiveness of motor and nonmotor symptoms of Parkinson disease to dopaminergic therapy.
Progress in neuro-psychopharmacology & biological psychiatry 2010;34(1):57-61.
2010: Michael E Thase; Harald Murck; Anke Post
Clinical relevance of disturbances of sleep and vigilance in major depressive disorder: a review.
Primary care companion to the Journal of clinical psychiatry 2010;12(6):.
2009: Harald Murck; Mirjam I Schubert; Dagmar Schmid; Petra Schüssler; Axel Steiger; Dorothee P Auer
The glutamatergic system and its relation to the clinical effect of therapeutic-sleep deprivation in depression - an MR spectroscopy study.
Journal of psychiatric research 2009;43(3):175-80.
2007: Harald Murck; Mehar Manku
Ethyl-EPA in Huntington disease: potentially relevant mechanism of action.
Brain research bulletin 2007;72(2-3):159-64.
2007: Harald Murck; Axel Steiger; Ralf-Michael Frieboes; Irina A Antonijevic
Pituitary adenylate cyclase-activating peptide affects homeostatic sleep regulation in healthy young men.
American journal of physiology. Endocrinology and metabolism 2007;292(3):E853-7.
2006: Robin Emsley; Dana J H Niehaus; Liezl Koen; Piet P Oosthuizen; H Jadri Turner; Paul Carey; Susan J van Rensburg; J Stephanus Maritz; Harald Murck
The effects of eicosapentaenoic acid in tardive dyskinesia: a randomized, placebo-controlled trial.
Schizophrenia research 2006;84(1):112-20.
2006: Harald Murck; Heidi Spitznagel; Michael Ploch; Klaus Seibel; Klaus Schaffler
Hypericum extract reverses S-ketamine-induced changes in auditory evoked potentials in humans - possible implications for the treatment of schizophrenia.
Biological psychiatry 2006;59(5):440-5.
2006: Harald Murck; Manfred Uhr; Marc Ziegenbein; Heike E Künzel; Katja Held; Irina A Antonijevic; Petra Schüssler; Axel Steiger
Renin-angiotensin-aldosterone system, HPA-axis and sleep-EEG changes in unmedicated patients with depression after total sleep deprivation.
Pharmacopsychiatry 2006;39(1):23-9.
2006: Katja Held; Irina A Antonijevic; Harald Murck; Heike E Kuenzel; Axel Steiger
Neuropeptide Y (NPY) shortens sleep latency but does not suppress ACTH and cortisol in depressed patients and normal controls.
Psychoneuroendocrinology 2006;31(1):100-7.
2005: Maurizio Fava; Jonathan Alpert; Andrew A Nierenberg; David Mischoulon; Michael W Otto; John M Zajecka; Harald Murck; Jerrold F Rosenbaum
A Double-blind, randomized trial of St John's wort, fluoxetine, and placebo in major depressive disorder.
Journal of clinical psychopharmacology 2005;25(5):441-7.
2005: Basant K Puri; Blair R Leavitt; Michael R Hayden; Christopher A Ross; Adam Rosenblatt; J Timothy Greenamyre; Steven M Hersch; Krishna S Vaddadi; A Sword; David F Horrobin; Mehar Manku; Harald Murck
Ethyl-EPA in Huntington disease: a double-blind, randomized, placebo-controlled trial.
Neurology 2005;65(2):286-92.
2005: Heike E Kuenzel; Axel Steiger; Katja Held; Irina A Antonijevic; Ralf-Michael Frieboes; Harald Murck
Changes in sleep electroencephalogram and nocturnal hormone secretion after administration of the antidyskinetic agent sarizotan in healthy young male volunteers.
Psychopharmacology 2005;180(2):327-32.
2005: Harald Murck; Maurizio Fava; Jonathan Alpert; Andrew A Nierenberg; David Mischoulon; Michael W Otto; John M Zajecka; Marcus Mannel; Jerrold F Rosenbaum
Hypericum extract in patients with MDD and reversed vegetative signs: re-analysis from data of a double-blind, randomized trial of hypericum extract, fluoxetine, and placebo.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2005;8(2):215-21.
2005: Katja Held; Irina A Antonijevic; Harald Murck; Heike E Künzel; Axel Steiger
Alpha-helical CRH exerts CRH agonistic effects on sleep-endocrine activity in humans.
Neuropsychobiology 2005;52(2):62-7.
2005: Harald Jörn Schneider; Heide Oertel; Harald Murck; Thomas Pollmächer; Günter K Stalla; Axel Steiger
Night sleep EEG and daytime sleep propensity in adult hypopituitary patients with growth hormone deficiency before and after six months of growth hormone replacement.
Psychoneuroendocrinology 2005;30(1):29-37.
2004: Nicolas Singewald; Catrin Sinner; Alfred Hetzenauer; Simone B Sartori; Harald Murck
Magnesium-deficient diet alters depression- and anxiety-related behavior in mice--influence of desipramine and Hypericum perforatum extract.
Neuropharmacology 2004;47(8):1189-97.
2004: Harald Murck; Katja Held; Marc Ziegenbein; Heike E Künzel; Florian Holsboer; Axel Steiger
Intravenous administration of the neuropeptide galanin has fast antidepressant efficacy and affects the sleep EEG.
Psychoneuroendocrinology 2004;29(9):1205-11.
2004: Heike E Kuenzel; Harald Murck; Katja Held; Marc Ziegenbein; Axel Steiger
Reboxetine induces similar sleep-EEG changes like SSRI's in patients with depression.
Pharmacopsychiatry 2004;37(5):193-5.
2004: Harald Murck; Cai Song; David F Horrobin; Manfred Uhr
Ethyl-eicosapentaenoate and dexamethasone resistance in therapy-refractory depression.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2004;7(3):341-9.
2004: Ralf-Michael Frieboes; Irina A Antonijevic; Katja Held; Harald Murck; Thomas Pollmächer; Manfred Uhr; Axel Steiger
Hexarelin decreases slow-wave sleep and stimulates the secretion of GH, ACTH, cortisol and prolactin during sleep in healthy volunteers.
Psychoneuroendocrinology 2004;29(7):851-60.
2004: Thomas Müller; Marcus Mannel; Harald Murck; Volker W Rahlfs
Treatment of somatoform disorders with St. John's wort: a randomized, double-blind and placebo-controlled trial.
Psychosomatic medicine 2004;66(4):538-47.
2004: Katja Held; Heike E Künzel; Marcus Ising; Dagmar A Schmid; Astrid Zobel; Harald Murck; Florian Holsboer; Axel Steiger
Treatment with the CRH1-receptor-antagonist R121919 improves sleep-EEG in patients with depression.
Journal of psychiatric research 2004;38(2):129-36.
2004: Harald Murck; Manfred Uhr; Klaus Schaffler; Klaus Seibel
Effects of Hypericum extract (LI160) on the change of auditory evoked potentials by cortisol administration.
Neuropsychobiology 2004;50(2):128-33.
2004: Mike Franklin; Alison Reed; Harald Murck
Sub-chronic treatment with an extract of Hypericum perforatum (St John's wort) significantly reduces cortisol and corticosterone in the rat brain.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2004;14(1):7-10.
2004: Marc Ziegenbein; Katja Held; Heike E Kuenzel; Harald Murck; Irina A Antonijevic; Axel Steiger
The somatostatin analogue octreotide impairs sleep and decreases EEG sigma power in young male subjects.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(1):146-51.
2003: Harald Murck; Katja Held; Marc Ziegenbein; Heike E Künzel; Kathrin Koch; Axel Steiger
The renin-angiotensin-aldosterone system in patients with depression compared to controls--a sleep endocrine study.
BMC psychiatry 2003;3():15.
2003: Mehar Manku; Iain Glen; Susan McGoldrick; Fiona Duffy; David Boal; Harald Murck; Amanda Green
Dr. David F. Horrobin.
Prostaglandins, leukotrienes, and essential fatty acids 2003;69(1):1-26.
2003: Thomas Nickel; Annette Sonntag; Julia Schill; Astrid Zobel; Nibal Ackl; Alexander Brunnauer; Harald Murck; Marcus Ising; Alexander Yassouridis; Axel Steiger; Josef Zihl; Florian Holsboer
Clinical and neurobiological effects of tianeptine and paroxetine in major depression.
Journal of clinical psychopharmacology 2003;23(2):155-68.
2003: Irina A Antonijevic; Harald Murck; Ralf-Michael Frieboes; Manfred Uhr; Axel Steiger
On the role of menopause for sleep-endocrine alterations associated with major depression.
Psychoneuroendocrinology 2003;28(3):401-18.
2003: Harald Murck; Thomas Nickel; Heike E Künzel; Irina A Antonijevic; Julia Schill; Astrid Zobel; Axel Steiger; Annette Sonntag; Florian Holsboer
State markers of depression in sleep EEG: dependency on drug and gender in patients treated with tianeptine or paroxetine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(2):348-58.
2002: Hans-Peter Volz; Harald Murck; Siegfried Kasper; Hans-Jürgen Möller
St John's wort extract (LI 160) in somatoform disorders: results of a placebo-controlled trial.
Psychopharmacology 2002;164(3):294-300.
2002: Katja Held; Irina A Antonijevic; Heike E Künzel; Manfred Uhr; Thomas C Wetter; I C Golly; Axel Steiger; Harald Murck
Oral Mg(2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humans.
Pharmacopsychiatry 2002;35(4):135-43.
2002: Christian Peteranderl; Irina A Antonijevic; Axel Steiger; Harald Murck; Katja Held; Ralf-Michael Frieboes; Manfred Uhr; Ludwig Schaaf
Nocturnal secretion of TSH and ACTH in male patients with depression and healthy controls.
Journal of psychiatric research 2002;36(3):189-96.
2002: Harald Murck; Tobias Struttmann; Michael Czisch; Thomas Wetter; Axel Steiger; Dorothee P Auer
Increase in amino acids in the pons after sleep deprivation: a pilot study using proton magnetic resonance spectroscopy.
Neuropsychobiology 2002;45(3):120-3.
2001: Harald Murck; Ralf-Michael Frieboes; Irina A Antonijevic; Axel Steiger
Distinct temporal pattern of the effects of the combined serotonin-reuptake inhibitor and 5-HT1A agonist EMD 68843 on the sleep EEG in healthy men.
Psychopharmacology 2001;155(2):187-92.
2000: Irina A Antonijevic; Harald Murck; S Bohlhalter; Ralf-Michael Frieboes; Florian Holsboer; Axel Steiger
Neuropeptide Y promotes sleep and inhibits ACTH and cortisol release in young men.
Neuropharmacology 2000;39(8):1474-81.
2000: Hirokuni Tagaya; Lorenz Trachsel; Harald Murck; Irina A Antonijevic; Axel Steiger; Florian Holsboer; Elisabeth Friess
Temporal EEG dynamics of non-REM sleep episodes in humans.
Brain research 2000;861(2):233-40.
2000: Irina A Antonijevic; Harald Murck; Ralf-Michael Frieboes; Axel Steiger
Sexually dimorphic effects of GHRH on sleep-endocrine activity in patients with depression and normal controls - part II: hormone secretion.
Sleep research online : SRO 2000;3(1):15-21.
2000: Irina A Antonijevic; Harald Murck; Ralf-Michael Frieboes; J Barthelmes; Axel Steiger
Sexually dimorphic effects of GHRH on sleep-endocrine activity in patients with depression and normal controls - part I: the sleep eeg.
Sleep research online : SRO 2000;3(1):5-13.
1999: Harald Murck; Irina A Antonijevic; T Schier; Ralf-Michael Frieboes; J Barthelmes; Axel Steiger
Aging does not affect the sleep endocrine response to total sleep deprivation in humans.
Neurobiology of aging 1999;20(6):665-8.
1999: Irina A Antonijevic; Harald Murck; Ralf-Michael Frieboes; Florian Holsboer; Axel Steiger
On the gender differences in sleep-endocrine regulation in young normal humans.
Neuroendocrinology 1999;70(4):280-7.
1999: Ralf-Michael Frieboes; Harald Murck; Irina A Antonijevic; Axel Steiger
Effects of growth hormone-releasing peptide-6 on the nocturnal secretion of GH, ACTH and cortisol and on the sleep EEG in man: role of routes of administration.
Journal of neuroendocrinology 1999;11(6):473-8.
1999: Harald Murck; Irina A Antonijevic; Ralf-Michael Frieboes; P Maier; T Schier; Axel Steiger
Galanin has REM-sleep deprivation-like effects on the sleep EEG in healthy young men.
Journal of psychiatric research 1999;33(3):225-32.
1999: Irina A Antonijevic; Harald Murck; Ralf-Michael Frieboes; T T Holsboer; Axel Steiger
Hyporesponsiveness of the pituitary to CRH during slow wave sleep is not mimicked by systemic GHRH.
Neuroendocrinology 1999;69(2):88-96.
1999: Ralf-Michael Frieboes; Ulrich Müller; Harald Murck; D Yves von Cramon; Florian Holsboer; Axel Steiger
Nocturnal hormone secretion and the sleep EEG in patients several months after traumatic brain injury.
The Journal of neuropsychiatry and clinical neurosciences 1999;11(3):354-60.
1999: Ralf-Michael Frieboes; Harald Murck; Irina A Antonijevic; T Kraus; Dunja Hinze-Selch; Thomas Pollmächer; Axel Steiger
Characterization of the sigma ligand panamesine, a potential antipsychotic, by immune response in patients with schizophrenia and by sleep-EEG changes in normal controls.
Psychopharmacology 1999;141(1):107-10.
1998: Irina A Antonijevic; Harald Murck; Ralf-Michael Frieboes; R Horn; G Brabant; Axel Steiger
Elevated nocturnal profiles of serum leptin in patients with depression.
Journal of psychiatric research 1998;32(6):403-10.
1998: Ralf-Michael Frieboes; Harald Murck; Günter K Stalla; Irina A Antonijevic; Axel Steiger
Enhanced slow wave sleep in patients with prolactinoma.
The Journal of clinical endocrinology and metabolism 1998;83(8):2706-10.
1998: Harald Murck; Axel Steiger
Mg2+ reduces ACTH secretion and enhances spindle power without changing delta power during sleep in men -- possible therapeutic implications.
Psychopharmacology 1998;137(3):247-52.
1998: Axel Steiger; Irina A Antonijevic; S Bohlhalter; Ralf-Michael Frieboes; Elisabeth Friess; Harald Murck
Effects of hormones on sleep.
Hormone research 1998;49(3-4):125-30.
1997: S Bohlhalter; Harald Murck; Florian Holsboer; Axel Steiger
Cortisol enhances non-REM sleep and growth hormone secretion in elderly subjects.
Neurobiology of aging 1997;18(4):423-9.
1997: Ralf-Michael Frieboes; Harald Murck; Klaus Wiedemann; Florian Holsboer; Axel Steiger
Open clinical trial on the sigma ligand panamesine in patients with schizophrenia.
Psychopharmacology 1997;132(1):82-8.
1997: Harald Murck; Ralf-Michael Frieboes; T Schier; Axel Steiger
Longtime administration of growth hormone-releasing hormone (GHRH) does not restore the reduced efficiency of GHRH on sleep endocrine activity in 2 old-aged subjects--a preliminary study.
Pharmacopsychiatry 1997;30(4):122-4.
1997: Ralf-Michael Frieboes; Harald Murck; T Schier; Florian Holsboer; Axel Steiger
Somatostatin impairs sleep in elderly human subjects.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;16(5):339-45.
1996: Harald Murck; J Guldner; M Colla-Müller; Ralf-Michael Frieboes; T Schier; Klaus Wiedemann; Florian Holsboer; Axel Steiger
VIP decelerates non-REM-REM cycles and modulates hormone secretion during sleep in men.
The American journal of physiology 1996;271(4 Pt 2):R905-11.
1996: Axel Steiger; M Colla-Müller; Ralf-Michael Frieboes; J Guldner; Harald Murck; T Schier
[The role of neuropeptides in normal and disordered sleep regulation].
Wiener medizinische Wochenschrift (1946) 1996;146(13-14):291-3.
1995: Ralf-Michael Frieboes; Harald Murck; P Maier; T Schier; Florian Holsboer; Axel Steiger
Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol release in normal man.
Neuroendocrinology 1995;61(5):584-9.
1995: Ralf-Michael Frieboes; T Schier; J Guldner; M Colla-Müller; Harald Murck; Axel Steiger
[Action of growth hormone releasing hormone (GHRH) on sleep EEG and nocturnal secretion of growth hormone, cortisol and ACTH in patients with major depression].
Wiener medizinische Wochenschrift (1946) 1995;145(17-18):499-500.