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Anne Murphy

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Publications

TOP 3
Jonathan A Kirk; Anne M Murphy; Pingbo Zhang; Jennifer E Van Eyk
Troponin I alterations detected by multiple-reaction monitoring: how might this impact the study of heart failure?
Paul J M Wijnker; Cristobal G dos Remedios; Darren Foster; Aisha H Frazier; Anne M Murphy; Ger J M Stienen; Allison L Tsao; Jolanda van der Velden
Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes.
Jill A Fahrner; Anne M Murphy; Meral Gunay-Aygun
Hypertrophic cardiomyopathy: how far should we go with genetic testing?

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All Publications

2013: Jonathan A Kirk; Anne M Murphy; Pingbo Zhang; Jennifer E Van Eyk
Troponin I alterations detected by multiple-reaction monitoring: how might this impact the study of heart failure?
Expert review of proteomics 2013;10(1):5-8.
2013: Paul J M Wijnker; Cristobal G dos Remedios; Darren Foster; Aisha H Frazier; Anne M Murphy; Ger J M Stienen; Allison L Tsao; Jolanda van der Velden
Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 2013;304(2):H260-8.
2013: Jill A Fahrner; Anne M Murphy; Meral Gunay-Aygun
Hypertrophic cardiomyopathy: how far should we go with genetic testing?
American journal of medical genetics. Part A 2013;161A(1):232-3.
2012: Anne M Murphy
Healing hearts and minds: can antidepressants repair the heart?
Journal of molecular and cellular cardiology 2012;53(6):749-50.
2012: Pingbo Zhang; Jennifer E Van Eyk; Cristobal G dos Remedios; Weihua Ji; David A Kass; Jonathan A Kirk; Anne M Murphy
Multiple reaction monitoring to identify site-specific troponin I phosphorylated residues in the failing human heart.
Circulation 2012;126(15):1828-37.
2012: Steven R Houser; David A Kass; Walter Koch; Walter J Koch; Kenneth B Margulies; Jeffery D Molkentin; Anne M Murphy; Sumanth D Prabhu; Howard A Rockman; Francis G Spinale; Mark A Sussman; Gary S Francis
Animal models of heart failure: a scientific statement from the American Heart Association.
Circulation research 2012;111(1):131-50.
2012: Jill A Fahrner; Aisha Frazier; Carolyn D Applegate; Suha Bachir; Marc K Halushka; Anne M Murphy; W Reid Thompson; Michael F Walsh; Meral Gunay-Aygun
A rasopathy phenotype with severe congenital hypertrophic obstructive cardiomyopathy associated with a PTPN11 mutation and a novel variant in SOS1.
American journal of medical genetics. Part A 2012;158A(6):1414-21.
2010: William Reardon; Veronica Donoghue; Anne M Murphy; Mary D King; Philip D Mayne; Nina Horn; Lisbeth Birk Møller
Progressive cerebellar degenerative changes in the severe mental retardation syndrome caused by duplication of MECP2 and adjacent loci on Xq28.
European journal of pediatrics 2010;169(8):941-9.
2010: Genaro A Ramirez Correa; Sonia Cortassa; Brian Stanley; Wei Dong Gao; Anne M Murphy
Calcium sensitivity, force frequency relationship and cardiac troponin I: critical role of PKA and PKC phosphorylation sites.
Journal of molecular and cellular cardiology 2010;48(5):943-53.
2010: Viola Kooij; Martina Saes; Kornelia Jaquet; Ruud Zaremba; Darren Foster; Anne M Murphy; Cris Dos Remedios; Jolanda van der Velden; Ger J M Stienen
Effect of troponin I Ser23/24 phosphorylation on Ca2+-sensitivity in human myocardium depends on the phosphorylation background.
Journal of molecular and cellular cardiology 2010;48(5):954-63.
2010: Agnieszka Galińska; Victoria Hatch; Roger Craig; Anne M Murphy; Jennifer E Van Eyk; C-L Albert Wang; William Lehman; Darren Foster
The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments.
Circulation research 2010;106(4):705-11.
2010: Anne M Murphy
Mammography screening for breast cancer: a view from 2 worlds.
JAMA : the journal of the American Medical Association 2010;303(2):166-7.
2009: Anne M Murphy
Early childhood development: One developmental paediatrician's story.
Paediatrics & child health 2009;14(10):669-70.
2008: Genaro A Ramirez Correa; Wenhai Jin; Zihao Wang; Xin Zhong; Wei Dong Gao; Wagner B Dias; Cecilia Vecoli; Gerald W Hart; Anne M Murphy
O-linked GlcNAc modification of cardiac myofilament proteins: a novel regulator of myocardial contractile function.
Circulation research 2008;103(12):1354-8.
2008: Anne M Murphy; Duke E Cameron
The Blalock-Taussig-Thomas collaboration: a model for medical progress.
JAMA : the journal of the American Medical Association 2008;300(3):328-30.
2008: Aisha Frazier; Daniel P Judge; Steven P Schulman; Nicole Johnson; Kathryn W Holmes; Anne M Murphy
Familial hypertrophic cardiomyopathy associated with cardiac beta-myosin heavy chain and troponin I mutations.
Pediatric cardiology 2008;29(4):846-50.
2008: Wenhai Jin; Anna T Brown; Anne M Murphy
Cardiac myofilaments: from proteome to pathophysiology.
Proteomics. Clinical applications 2008;2(6):800-10.
2007: Genaro A Ramirez Correa; Anne M Murphy
Is phospholamban or troponin I the "prima donna" in beta-adrenergic induced lusitropy?
Circulation research 2007;101(4):326-7.
2007: Aisha Frazier; Anne M Murphy
Repairing the myofilaments to heal the heart.
American journal of physiology. Heart and circulatory physiology 2007;293(2):H907-8.
2007: Tieying Dai; Ye Tian; Carlo G Tocchetti; Tatsuo Katori; Anne M Murphy; David A Kass; Nazareno Paolocci; Wei Dong Gao
Nitroxyl increases force development in rat cardiac muscle.
The Journal of physiology 2007;580(Pt.3):951-60.
2007: Wei Dong Gao; Anne M Murphy
Local control in thin filament activation of cardiac muscle.
The Journal of physiology 2007;580(Pt. 2):358.
2007: Kenneth C Bilchick; Jennifer G Duncan; Rajashree Ravi; Eiki Takimoto; Hunter C Champion; Wei Dong Gao; Linda B Stull; David A Kass; Anne M Murphy
Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function.
American journal of physiology. Heart and circulatory physiology 2007;292(1):H318-25.
2006: Nadiya A Narolska; Nicoletta Piroddi; Alexandra Belus; Nicky M Boontje; Beatrice Scellini; Sascha Deppermann; Ruud Zaremba; René J P Musters; Cris dos Remedios; Kornelia Jaquet; Darren Foster; Anne M Murphy; Jennifer E Van Eyk; Chiara Tesi; Corrado Poggesi; Jolanda van der Velden; Ger J M Stienen
Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle.
Circulation research 2006;99(9):1012-20.
2006: D. Kent Arrell; Steven T Elliott; Lesley A Kane; Yurong Guo; Young H Ko; Peter L Pedersen; John Robinson; Mitsushige Murata; Anne M Murphy; Eduardo Marban; Jennifer E Van Eyk
Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways.
Circulation research 2006;99(7):706-14.
2006: Chao Yuan; Yurong Guo; Rajashree Ravi; Karin Przyklenk; Nicole A Shilkofski; roberto diez; Robert N Cole; Anne M Murphy
Myosin binding protein C is differentially phosphorylated upon myocardial stunning in canine and rat hearts-- evidence for novel phosphorylation sites.
Proteomics 2006;6(14):4176-86.
2006: Anne M Murphy
Heart failure, myocardial stunning, and troponin: a key regulator of the cardiac myofilament.
Congestive heart failure (Greenwich, Conn.) 2006;12(1):32-8; quiz 39-40.
2005: Jennifer G Duncan; Rajashree Ravi; Linda B Stull; Anne M Murphy
Chronic xanthine oxidase inhibition prevents myofibrillar protein oxidation and preserves cardiac function in a transgenic mouse model of cardiomyopathy.
American journal of physiology. Heart and circulatory physiology 2005;289(4):H1512-8.
2005: Chao Yuan; Rajashree Ravi; Anne M Murphy
Discovery of disease-induced post-translational modifications in cardiac contractile proteins.
Current opinion in molecular therapeutics 2005;7(3):234-9.
2004: Anne M Murphy
Another new kinase targets troponin I.
Circulation research 2004;95(11):1043-5.
2004: David G Soergel; Gerasimos F. Kremmydas; Linda B Stull; David A Kass; Anne M Murphy
Augmented systolic response to the calcium sensitizer EMD-57033 in a transgenic model with troponin I truncation.
American journal of physiology. Heart and circulatory physiology 2004;286(5):H1785-92.
2004: Eiki Takimoto; David G Soergel; Paul Janssen; Linda B Stull; David A Kass; Anne M Murphy
Frequency- and afterload-dependent cardiac modulation in vivo by troponin I with constitutively active protein kinase A phosphorylation sites.
Circulation research 2004;94(4):496-504.
2003: Darren Foster; Teruo Noguchi; Peter VanBuren; Anne M Murphy; Jennifer E Van Eyk
C-terminal truncation of cardiac troponin I causes divergent effects on ATPase and force: implications for the pathophysiology of myocardial stunning.
Circulation research 2003;93(10):917-24.
2003: Hein J Verberne; Gerrit W Sloof; Arnold L Beets; Anne M Murphy; Berthe L F van Eck-Smit; Furn F Knapp
125I-BMIPP and 18F-FDG uptake in a transgenic mouse model of stunned myocardium.
European journal of nuclear medicine and molecular imaging 2003;30(3):431-9.
2002: Anne M Murphy
Troponin I: in sickness and in health-and normal development.
Circulation research 2002;91(6):449-50.
2002: Irene L Ennis; Ronald A Li; Anne M Murphy; Eduardo Marban; H Bradley Nuss
Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility.
The Journal of clinical investigation 2002;109(3):393-400.
2001: Jennifer E Van Eyk; Anne M Murphy
The role of troponin abnormalities as a cause for stunned myocardium.
Coronary artery disease 2001;12(5):343-7.
2001: Harald Kögler; David G Soergel; Anne M Murphy; Eduardo Marban
Maintained contractile reserve in a transgenic mouse model of myocardial stunning.
American journal of physiology. Heart and circulatory physiology 2001;280(6):H2623-30.
2001: A B Hirshfeld; W Reid Thompson; Ankita Patel; L B Boone; Anne M Murphy
Proximal trisomy of 1q mosaicism in a girl with hypertrophic cardiomyopathy associated with Wolff-Parkinson-White syndrome and multiple congenital anomalies.
American journal of medical genetics 2001;100(4):264-8.
2001: Wendy R Kates; Courtney P Burnette; Ethylin Jabs; Julie Rutberg; Anne M Murphy; Grados Marco; Michael T Geraghty; Walter E Kaufmann; Godfrey D Pearlson
Regional cortical white matter reductions in velocardiofacial syndrome: a volumetric MRI analysis.
Biological psychiatry 2001;49(8):677-84.
2000: Anne M Murphy; Harald Kögler; Eduardo Marban
A mouse model of myocardial stunning.
Molecular medicine today 2000;6(8):330-1.
2000: Anne M Murphy; Harald Kögler; Gerasimos F. Kremmydas; Jason L McDonough; David A Kass; Jennifer E Van Eyk; Eduardo Marban
Transgenic mouse model of stunned myocardium.
Science (New York, N.Y.) 2000;287(5452):488-91.
1998: V Lemes; Anne M Murphy; F A Osterman; JC Laschinger; J S Kan
Fenestration of extracardiac fontan and reversal of protein-losing enteropathy: case report.
Pediatric cardiology 1998;19(4):355-7.
1997: Anne M Murphy; W Reid Thompson; L F Peng; L Jones
Regulation of the rat cardiac troponin I gene by the transcription factor GATA-4.
The Biochemical journal 1997;322 ( Pt 2)():393-401.
1997: Wei Dong Gao; D Atar; Yongge Liu; N G Perez; Anne M Murphy; Eduardo Marban
Role of troponin I proteolysis in the pathogenesis of stunned myocardium.
Circulation research 1997;80(3):393-9.
1996: J A Oski; C E Canter; T L Spray; J S Kan; Duke E Cameron; Anne M Murphy
Embolic stroke after ligation of the pulmonary artery in patients with functional single ventricle.
American heart journal 1996;132(4):836-40.
1996: Anne M Murphy; Denise Montell
Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis.
The Journal of cell biology 1996;133(3):617-30.
1996: Anne M Murphy
Contractile protein phenotypic variation during development.
Cardiovascular research 1996;31 Spec No():E25-33.
1995: Anne M Murphy; T Lee; C M Andrews; B Z Shilo; Denise Montell
The breathless FGF receptor homolog, a downstream target of Drosophila C/EBP in the developmental control of cell migration.
Development (Cambridge, England) 1995;121(8):2255-63.
1995: D Begley; Anne M Murphy; C Hiu; S I Tsubota
Modifier of rudimentary p1, mod(r)p1, a trans-acting regulatory mutation of rudimentary.
Molecular & general genetics : MGG 1995;248(1):69-78.
1994: E Wojcik; Anne M Murphy; H Fares; K Dang-Vu; S I Tsubota
Enhancer of rudimentaryp1, e(r)p1, a highly conserved enhancer of the rudimentary gene.
Genetics 1994;138(4):1163-70.
1994: Marci Surpin; F Moshiri; Anne M Murphy; Robert J Maier
Genetic evidence for a fourth terminal oxidase in Bradyrhizobium japonicum.
Gene 1994;143(1):73-7.
1994: X Guo; Jonggonnee Wattanapermpool; K A Palmiter; Anne M Murphy; R John Solaro
Mutagenesis of cardiac troponin I. Role of the unique NH2-terminal peptide in myofilament activation.
The Journal of biological chemistry 1994;269(21):15210-6.
1994: V Averyhart-Fullard; L D Fraker; Anne M Murphy; R John Solaro
Differential regulation of slow-skeletal and cardiac troponin I mRNA during development and by thyroid hormone in rat heart.
Journal of molecular and cellular cardiology 1994;26(5):609-16.
1994: Lawrence M Nogee; G Garnier; Harry C Dietz; L Singer; Anne M Murphy; Daphne E Demello; HR Colten
A mutation in the surfactant protein B gene responsible for fatal neonatal respiratory disease in multiple kindreds.
The Journal of clinical investigation 1994;93(4):1860-3.
1992: Péter P Nánási; T K Knilans; András Varró; Anne M Murphy; A Fujiki; Arnold Schwartz; David Austin Lathrop
Active and passive electrical properties of isolated canine cardiac Purkinje fibers under conditions simulating ischaemia: effect of diltiazem.
Pharmacology & toxicology 1992;71(1):52-6.
1992: M C Johnson; S So; J W Marsh; Anne M Murphy
QT prolongation and Torsades de Pointes after administration of FK506.
Transplantation 1992;53(4):929-30.
1991: N M Hunkeler; J Kullman; Anne M Murphy
Troponin I isoform expression in human heart.
Circulation research 1991;69(5):1409-14.
1991: Anne M Murphy; L Jones; H F Sims; Arnold W Strauss
Molecular cloning of rat cardiac troponin I and analysis of troponin I isoform expression in developing rat heart.
Biochemistry 1991;30(3):707-12.
1990: Anne M Murphy; R John Solaro
Developmental difference in the stimulation of cardiac myofibrillar Mg2(+)-ATPase activity by calmidazolium.
Pediatric research 1990;28(1):46-9.
1989: Anne M Murphy; M Blades; S Daniels; F W James
Blood pressure and cardiac output during exercise: a longitudinal study of children undergoing repair of coarctation.
American heart journal 1989;117(6):1327-32.
1987: Anne M Murphy; W E Gaum; David Austin Lathrop; Ajaz Hussain; W A Ritschel; S Kaplan
Age-related digoxin effects in an intact canine model.
American heart journal 1987;114(3):583-8.
1985: David Austin Lathrop; Anne M Murphy; T Humphreys; A Schwartz
Effects of bepridil on force development and transmembrane electrical activity of adult canine Purkinje strands: comparison with nisoldipine and lidocaine.
European journal of pharmacology 1985;118(3):283-92.