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GM Murphy

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LA Thomas; MJ Veysey; GM Murphy; D Russell-Jones; Gary L French; J A H Wass; RH Dowling
Octreotide induced prolongation of colonic transit increases faecal anaerobic bacteria, bile acid metabolising enzymes, and serum deoxycholic acid in patients with acromegaly.
LA Thomas; MJ Veysey; Gary L French; Phillip B Hylemon; GM Murphy; RH Dowling
Bile acid metabolism by fresh human colonic contents: a comparison of caecal versus faecal samples.
MJ Veysey; PN Malcolm; AI Mallet; PJ Jenkins; GM Besser; GM Murphy; RH Dowling
Effects of cisapride on gall bladder emptying, intestinal transit, and serum deoxycholate: a prospective, randomised, double blind, placebo controlled trial.

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All Publications

2005: LA Thomas; MJ Veysey; GM Murphy; D Russell-Jones; Gary L French; J A H Wass; RH Dowling
Octreotide induced prolongation of colonic transit increases faecal anaerobic bacteria, bile acid metabolising enzymes, and serum deoxycholic acid in patients with acromegaly.
Gut 2005;54(5):630-5.
2001: LA Thomas; MJ Veysey; Gary L French; Phillip B Hylemon; GM Murphy; RH Dowling
Bile acid metabolism by fresh human colonic contents: a comparison of caecal versus faecal samples.
Gut 2001;49(6):835-42.
2001: MJ Veysey; PN Malcolm; AI Mallet; PJ Jenkins; GM Besser; GM Murphy; RH Dowling
Effects of cisapride on gall bladder emptying, intestinal transit, and serum deoxycholate: a prospective, randomised, double blind, placebo controlled trial.
Gut 2001;49(6):828-34.
2001: MJ Veysey; LA Thomas; AI Mallet; PJ Jenkins; GM Besser; GM Murphy; RH Dowling
Colonic transit influences deoxycholic acid kinetics.
Gastroenterology 2001;121(4):812-22.
2001: Stephen P Pereira; SH Hussaini; GM Murphy; J A H Wass; RH Dowling
Octreotide increases the proportions of arachidonic acid-rich phospholipids in gall-bladder bile.
Alimentary pharmacology & therapeutics 2001;15(9):1435-43.
2001: LA Thomas; MJ Veysey; GM Murphy; RH Dowling
Influence of pH on the phase distribution of nascent deoxycholic acid in fresh human cecal aspirates.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(2):G371-4.
2000: LA Thomas; MJ Veysey; T Bathgate; A King; Gary L French; N C Smeeton; GM Murphy; RH Dowling
Mechanism for the transit-induced increase in colonic deoxycholic acid formation in cholesterol cholelithiasis.
Gastroenterology 2000;119(3):806-15.
2000: V Milovic; J Stein; G Odera; S Gilani; GM Murphy
Low-dose deoxycholic acid stimulates putrescine uptake in colon cancer cells (Caco-2).
Cancer letters 2000;154(2):195-200.
1999: MJ Veysey; LA Thomas; AI Mallet; PJ Jenkins; GM Besser; J A H Wass; GM Murphy; RH Dowling
Prolonged large bowel transit increases serum deoxycholic acid: a risk factor for octreotide induced gallstones.
Gut 1999;44(5):675-81.
1998: Stephen P Pereira; J M Rhodes; B J Campbell; D Kumar; I M Bain; GM Murphy; RH Dowling
Biliary lactoferrin concentrations are increased in active inflammatory bowel disease: a factor in the pathogenesis of primary sclerosing cholangitis?
Clinical science (London, England : 1979) 1998;95(5):637-44.
1997: LA Thomas; A King; Gary L French; GM Murphy; RH Dowling
Cholylglycine hydrolase and 7alpha-dehydroxylase optimum assay conditions in vitro and caecal enzyme activities ex vivo.
Clinica chimica acta; international journal of clinical chemistry 1997;268(1-2):61-72.
1997: Stephen P Pereira; MJ Veysey; C Kennedy; SH Hussaini; GM Murphy; RH Dowling
Gallstone dissolution with oral bile acid therapy. Importance of pretreatment CT scanning and reasons for nonresponse.
Digestive diseases and sciences 1997;42(8):1775-82.
1997: RH Dowling; MJ Veysey; Stephen P Pereira; SH Hussaini; LA Thomas; J A H Wass; GM Murphy
Role of intestinal transit in the pathogenesis of gallbladder stones.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1997;11(1):57-64.
1996: Stephen P Pereira; T B Cassell; J L Engelman; G E Sladen; GM Murphy; RH Dowling
Plasma arachidonic acid-rich phospholipids in Crohn's disease: response to treatment.
Clinical science (London, England : 1979) 1996;91(4):509-12.
1996: S H Hussaini; Stephen P Pereira; MJ Veysey; C Kennedy; P Jenkins; GM Murphy; J A H Wass; RH Dowling
Roles of gall bladder emptying and intestinal transit in the pathogenesis of octreotide induced gall bladder stones.
Gut 1996;38(5):775-83.
1995: S H Hussaini; Stephen P Pereira; GM Murphy; RH Dowling
Deoxycholic acid influences cholesterol solubilization and microcrystal nucleation time in gallbladder bile.
Hepatology (Baltimore, Md.) 1995;22(6):1735-44.
1995: S S Sequeira; H G Parkes; JP Ellul; GM Murphy
In vitro determination by 1H-NMR studies that bile with shorter nucleation times contain cholesterol-enriched vesicles.
Biochimica et biophysica acta 1995;1256(3):360-6.
1995: D Gleeson; GM Murphy; RH Dowling
Effect of acute bile acid pool depletion on total and ionized calcium concentrations in human bile.
European journal of clinical investigation 1995;25(4):225-34.
1995: S H Hussaini; Stephen P Pereira; GM Murphy; C Kennedy; J A H Wass; G M Besser; RH Dowling
Composition of gall bladder stones associated with octreotide: response to oral ursodeoxycholic acid.
Gut 1995;36(1):126-32.
1994: D Gleeson; GM Murphy; RH Dowling
Changes in serum calcium levels influence biliary calcium levels in humans.
Gastroenterology 1994;107(6):1812-8.
1994: S H Hussaini; GM Murphy; C Kennedy; G M Besser; J A H Wass; RH Dowling
The role of bile composition and physical chemistry in the pathogenesis of octreotide-associated gallbladder stones.
Gastroenterology 1994;107(5):1503-13.
1994: Y Sawada; Stephen P Pereira; GM Murphy; RH Dowling
Polyamines in the intestinal lumen of patients with small bowel bacterial overgrowth.
Biochemical Society transactions 1994;22(4):392S.
1994: A A Santos; A P Stubbs; M Maghsoudloo; GM Murphy; M L Wilkinson
Polyamine metabolism in human hepatocellular cancer cells (Hep-G2).
Biochemical Society transactions 1994;22(4):385S.
1994: A P Stubbs; J L Engelman; J I Walker; P Faik; GM Murphy; M L Wilkinson
Measurement of androgen receptor expression in adult liver, fetal liver, and Hep-G2 cells by the polymerase chain reaction.
Gut 1994;35(5):683-6.
1994: T B Cassell; Stephen P Pereira; D N Prashad; GM Murphy
Molecular species of phosphatidylcholine in bile, plasma and red blood cell membranes.
Biochemical Society transactions 1994;22(2):115S.
1994: S S Sequeira; H G Parkes; JP Ellul; GM Murphy
One dimensional high resolution 1H NMR spectroscopy of human bile: lipid-derived resonance shifts.
Biochemical Society transactions 1994;22(2):114S.
1994: D Armstrong; E R Rytina; GM Murphy; RH Dowling
Gastric mucosal toxicity of duodenal juice constituents in the rat. Acute studies using ex vivo rat gastric chamber model.
Digestive diseases and sciences 1994;39(2):327-39.
1993: R J Suckling; GM Murphy; M J Higgins
Human liver bile acid sulphotransferase: characterisation of the partially purified enzyme.
Biochemical Society transactions 1993;21(4):447S.
1993: RH Dowling; S H Hussaini; GM Murphy; J A H Wass
Gallstones during octreotide therapy.
Digestion 1993;54 Suppl 1():107-20.
1992: RH Dowling; S H Hussaini; GM Murphy; G M Besser; J A H Wass
Gallstones during octreotide therapy.
Metabolism: clinical and experimental 1992;41(9 Suppl 2):22-33.
1992: D Gleeson; K A Hood; GM Murphy; RH Dowling
Calcium and carbonate ion concentrations in gallbladder and hepatic bile.
Gastroenterology 1992;102(5):1707-16.
1992: M Maghsoudloo; M J Higgins; GM Murphy
Purification of human foetal hepatic bile acid sulphotransferase (BAST).
Biochemical Society transactions 1992;20(2):167S.
1992: JP Ellul; Richard Groves; J R Walters; GM Murphy
Lichen planus associated with chenodeoxycholic acid and ursodeoxycholic acid for gallstone dissolution.
Digestive diseases and sciences 1992;37(4):628-30.
1992: JP Ellul; GM Murphy; H G Parkes; R Z Slapa; RH Dowling
Nuclear magnetic resonance spectroscopy to determine the micellar cholesterol in human bile.
FEBS letters 1992;300(1):30-2.
1992: J R Walters; K A Hood; D Gleeson; JP Ellul; A Keightley; GM Murphy; RH Dowling
Combination therapy with oral ursodeoxycholic and chenodeoxycholic acids: pretreatment computed tomography of the gall bladder improves gall stone dissolution efficacy.
Gut 1992;33(3):375-80.
1991: P R Taylor; Robert C Mason; M I Filipe; S Vaja; D C Hanley; GM Murphy; RH Dowling; I McColl
Gastric carcinogenesis in the rat induced by duodenogastric reflux without carcinogens: morphology, mucin histochemistry, polyamine metabolism, and labelling index.
Gut 1991;32(12):1447-54.
1991: P J Howard; GM Murphy; R H Dowling
Gall bladder emptying patterns in response to a normal meal in healthy subjects and patients with gall stones: ultrasound study.
Gut 1991;32(11):1406-11.
1991: A P Stubbs; GM Murphy; M L Wilkinson
Isocratic high-performance liquid chromatographic measurement of optimal 5 alpha-steroid reductase activity in Hep-G2 cells.
Journal of chromatography 1991;570(2):293-9.
1991: C H Smith; M Maghsoudloo; K Himuna; GM Murphy
Pitfalls in the determination of diamine oxidase activity.
Clinica chimica acta; international journal of clinical chemistry 1991;201(1-2):89-94.
1990: A P Stubbs; S J Edmunds; GM Murphy; M L Wilkinson
Isocratic h.p.l.c. measurement of optimum 5-alpha steroid reductase activity.
Biochemical Society transactions 1990;18(6):1210.
1990: A P Stubbs; S E Edmunds; GM Murphy; M L Wilkinson
Testosterone metabolism in human hepatoma (Hep-G2) cells.
Biochemical Society transactions 1990;18(6):1210-1.
1990: D Gleeson; D C Ruppin; A Saunders; GM Murphy; RH Dowling
Final outcome of ursodeoxycholic acid treatment in 126 patients with radiolucent gallstones.
The Quarterly journal of medicine 1990;76(279):711-29.
1990: M H Lessof; Vanya Gant; K Hinuma; GM Murphy; RH Dowling
Recurrent urticaria and reduced diamine oxidase activity.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1990;20(4):373-6.
1990: T Rokkas; S Vaja; GM Murphy; RH Dowling
Postheparin plasma diamine oxidase in health and intestinal disease.
Gastroenterology 1990;98(6):1493-501.
1990: D Gleeson; GM Murphy; RH Dowling
Calcium binding by bile acids: in vitro studies using a calcium ion electrode.
Journal of lipid research 1990;31(5):781-91.
1990: T Rokkas; S Vaja; GM Murphy; RH Dowling
Aminoguanidine blocks intestinal diamine oxidase (DAO) activity and enhances the intestinal adaptive response to resection in the rat.
Digestion 1990;46 Suppl 2():447-57.
1990: T Rokkas; S Vaja; P Taylor; GM Murphy; RH Dowling
Is the intestine the sole source of heparin-stimulated plasma diamine oxidase? Acute effects of jejunectomy, ileectomy and total enterectomy.
Digestion 1990;46 Suppl 2():439-46.
1990: Tadao Bamba; S Vaja; GM Murphy; RH Dowling
Effect of fasting and feeding on polyamines and related enzymes along the villus: crypt axis.
Digestion 1990;46 Suppl 2():424-9.
1990: Tadao Bamba; S Vaja; GM Murphy; RH Dowling
Role of polyamines in the early adaptive response to jejunectomy in the rat: effect of DFMO on the ileal villus:crypt axis.
Digestion 1990;46 Suppl 2():410-23.
1990: T Rokkas; S Vaja; P Taylor; GM Murphy; RH Dowling
Effect of intestinal diamine oxidase (DAO) depletion by heparin on mucosal polyamine metabolism.
Digestion 1990;46 Suppl 2():378-82.
1989: P R Taylor; RH Dowling; T J Palmer; D C Hanley; GM Murphy; Robert C Mason; I McColl
Induction of pancreatic tumours by longterm duodenogastric reflux.
Gut 1989;30(11):1596-600.
1989: F Lirussi; S Vaja; GM Murphy; RH Dowling
Cholestasis of total parenteral nutrition: bile acid and bile lipid metabolism in parenterally nourished rats.
Gastroenterology 1989;96(2 Pt 1):493-502.
1989: P J Howard; D Gleeson; GM Murphy; RH Dowling
Ursocholic acid: bile acid and bile lipid dose response and clinical studies in patients with gall stones.
Gut 1989;30(1):97-103.
1988: D Armstrong; M Farrell; A Hanby; GM Murphy; RH Dowling
Is the ex vivo rat gastric chamber model suitable for studying the gastrotoxicity of refluxed duodenal contents? Initial results using deoxycholic acid.
Clinica chimica acta; international journal of clinical chemistry 1988;178(3):313-25.
1987: M Hosomi; N H Stace; F Lirussi; Stephen M Smith; GM Murphy; RH Dowling
Role of polyamines in intestinal adaptation in the rat.
European journal of clinical investigation 1987;17(5):375-85.
1987: M Hosomi; F Lirussi; N H Stace; S Vaja; GM Murphy; RH Dowling
Mucosal polyamine profile in normal and adapting (hypo and hyperplastic) intestine: effects of DFMO treatment.
Gut 1987;28 Suppl():103-7.
1986: D C Ruppin; GM Murphy; RH Dowling
Gall stone disease without gall stones--bile acid and bile lipid metabolism after complete gall stone dissolution.
Gut 1986;27(5):559-66.
1986: M Hosomi; S M Smith; GM Murphy; RH Dowling
Polyamine distribution in the rat intestinal mucosa.
Journal of chromatography 1986;375(2):267-75.
1985: RH Dowling; M Hosomi; N H Stace; F Lirussi; B Miazza; H Levan; GM Murphy
Hormones and polyamines in intestinal and pancreatic adaptation.
Scandinavian journal of gastroenterology. Supplement 1985;112():84-95.