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Robert Murphy

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Oxidation-Reduction

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Co-Publications
Name
13
Henson, Peter
12
Zarini, Simona
8
Zemski Berry, Karin
8
Travers, Jeffrey
7
Marathe, Gopal
7
Barkley, Robert
7
Harrison, Kathleen
6
Hankin, Joseph
6
McIntyre, Thomas
6
Voelker, Dennis
6
Zimmerman, Guy
5
Khaselev, N
5
Hevko, John
5
Folco, Giancarlo
5
Gijón, Miguel

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Publications

TOP 3
Poeckel Daniel; Zemski Berry Karin A; Murphy Robert C; Funk Colin D
Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.
Zarini Simona; Gijón Miguel A; Ransome Aaron E; Murphy Robert C; Sala Angelo
Transcellular biosynthesis of cysteinyl leukotrienes in vivo during mouse peritoneal inflammation.
Murphy Robert C; Hankin Joseph A; Barkley Robert M
Imaging of lipid species by MALDI mass spectrometry.

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All Publications

2009: Poeckel Daniel; Zemski Berry Karin A; Murphy Robert C; Funk Colin D
Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.
The Journal of biological chemistry 2009;284(31):21077-89.
2009: Zarini Simona; Gijón Miguel A; Ransome Aaron E; Murphy Robert C; Sala Angelo
Transcellular biosynthesis of cysteinyl leukotrienes in vivo during mouse peritoneal inflammation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(20):8296-301.
2009: Murphy Robert C; Hankin Joseph A; Barkley Robert M
Imaging of lipid species by MALDI mass spectrometry.
Journal of lipid research 2009;50 Suppl():S317-22.
2009: Bouvier Jérôme; Zemski Berry Karin A; Hullin-Matsuda Françoise; Makino Asami; Michaud Sabine; Geloën Alain; Murphy Robert C; Kobayashi Toshihide; Lagarde Michel; Delton-Vandenbroucke Isabelle
Selective decrease of bis(monoacylglycero)phosphate content in macrophages by high supplementation with docosahexaenoic acid.
Journal of lipid research 2009;50(2):243-55.
2008: Berry Karin A Zemski; Henson Peter M; Murphy Robert C
Effects of acrolein on leukotriene biosynthesis in human neutrophils.
Chemical research in toxicology 2008;21(12):2424-32.
2008: Frasch S Courtney; Berry Karin Zemski; Fernandez-Boyanapalli Ruby; Jin Hyun-Sun; Leslie Christina; Henson Peter M; Murphy Robert C; Bratton Donna L
NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A.
The Journal of biological chemistry 2008;283(48):33736-49.
2008: Gijón Miguel A; Riekhof Wayne R; Zarini Simona; Murphy Robert C; Voelker Dennis R
Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils.
The Journal of biological chemistry 2008;283(44):30235-45.
2008: Farias Santiago E; Basselin Mireille; Chang Lisa; Heidenreich Kim A; Rapoport Stanley I; Murphy Robert C
Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain.
Journal of lipid research 2008;49(9):1990-2000.
2008: Murphy Robert C; Johnson Kyle M
Cholesterol, reactive oxygen species, and the formation of biologically active mediators.
The Journal of biological chemistry 2008;283(23):15521-5.
2008: Hutchins Patrick M; Barkley Robert M; Murphy Robert C
Separation of cellular nonpolar neutral lipids by normal-phase chromatography and analysis by electrospray ionization mass spectrometry.
Journal of lipid research 2008;49(4):804-13.
2007: Riekhof Wayne R; Wu James; Gijón Miguel A; Zarini Simona; Murphy Robert C; Voelker Dennis R
Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation.
The Journal of biological chemistry 2007;282(51):36853-61.
2007: Farias Santiago E; Zarini Simona; Precht Thomas; Murphy Robert C; Heidenreich Kim A
Transcellular biosynthesis of cysteinyl leukotrienes in rat neuronal and glial cells.
Journal of neurochemistry 2007;103(4):1310-8.
2007: Hankin Joseph A; Barkley Robert M; Murphy Robert C
Sublimation as a method of matrix application for mass spectrometric imaging.
Journal of the American Society for Mass Spectrometry 2007;18(9):1646-52.
2007: Zemski Berry Karin A; Murphy Robert C
Characterization of acrolein-glycerophosphoethanolamine lipid adducts using electrospray mass spectrometry.
Chemical research in toxicology 2007;20(9):1342-51.
2007: Murphy Robert C; James Patrick F; McAnoy Andrew M; Krank Jessica; Duchoslav Eva; Barkley Robert M
Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry.
Analytical biochemistry 2007;366(1):59-70.
2007: Frasch S Courtney; Zemski-Berry Karin; Murphy Robert C; Borregaard Niels; Henson Peter M; Bratton Donna L
Lysophospholipids of different classes mobilize neutrophil secretory vesicles and induce redundant signaling through G2A.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6540-8.
2007: Fitzgerald Mark; Murphy Robert C
Electrospray mass spectrometry of human hair wax esters.
Journal of lipid research 2007;48(5):1231-46.
2007: Gijón Miguel A; Zarini Simona; Murphy Robert C
Biosynthesis of eicosanoids and transcellular metabolism of leukotrienes in murine bone marrow cells.
Journal of lipid research 2007;48(3):716-25.
2007: Krank Jessica; Murphy Robert C; Barkley Robert M; Duchoslav Eva; McAnoy Andrew
Qualitative analysis and quantitative assessment of changes in neutral glycerol lipid molecular species within cells.
Methods in enzymology 2007;432():1-20.
2006: Folco Giancarlo; Murphy Robert C
Eicosanoid transcellular biosynthesis: from cell-cell interactions to in vivo tissue responses.
Pharmacological reviews 2006;58(3):375-88.
2006: Zarini Simona; Gijón Miguel A; Folco Giancarlo; Murphy Robert C
Effect of arachidonic acid reacylation on leukotriene biosynthesis in human neutrophils stimulated with granulocyte-macrophage colony-stimulating factor and formyl-methionyl-leucyl-phenylalanine.
The Journal of biological chemistry 2006;281(15):10134-42.
2006: Zemski Berry Karin A; Murphy Robert C
Analysis of polyunsaturated aminophospholipid molecular species using isotope-tagged derivatives and tandem mass spectrometry/mass spectrometry/mass spectrometry.
Analytical biochemistry 2006;349(1):118-28.
2006: Chiba Hirofumi; Piboonpocanun Surapon; Mitsuzawa Hiroaki; Kuronuma Koji; Murphy Robert C; Voelker Dennis R
Pulmonary surfactant proteins and lipids as modulators of inflammation and innate immunity.
Respirology (Carlton, Vic.) 2006;11 Suppl():S2-6.
2006: Kirwan J Paul; Gould Ty A; Schweizer Herbert P; Bearden Scott W; Murphy Robert C; Churchill Mair E A
Quorum-sensing signal synthesis by the Yersinia pestis acyl-homoserine lactone synthase YspI.
Journal of bacteriology 2006;188(2):784-8.
2006: Gould Ty A; Herman Jake; Krank Jessica; Murphy Robert C; Churchill Mair E A
Specificity of acyl-homoserine lactone synthases examined by mass spectrometry.
Journal of bacteriology 2006;188(2):773-83.
2005: Murphy Robert C; Barkley Robert M; Zemski Berry Karin; Hankin Joseph; Harrison Kathleen; Johnson Chris; Krank Jessica; McAnoy Andrew; Uhlson Charis; Zarini Simona
Electrospray ionization and tandem mass spectrometry of eicosanoids.
Analytical biochemistry 2005;346(1):1-42.
2005: Marathe Gopal K; Johnson Christopher; Billings Steven D; Southall Michael D; Pei Yong; Spandau Dan; Murphy Robert C; Zimmerman Guy A; McIntyre Thomas M; Travers Jeffrey B
Ultraviolet B radiation generates platelet-activating factor-like phospholipids underlying cutaneous damage.
The Journal of biological chemistry 2005;280(42):35448-57.
2005: Murphy Robert C; Raetz Chris R H; Reynolds Clarence M; Barkley Robert M
Mass spectrometry advances in lipidomica: collision-induced decomposition of Kdo2-lipid A.
Prostaglandins & other lipid mediators 2005;77(1-4):131-40.
2005: McAnoy Andrew M; Wu Christine C; Murphy Robert C
Direct qualitative analysis of triacylglycerols by electrospray mass spectrometry using a linear ion trap.
Journal of the American Society for Mass Spectrometry 2005;16(9):1498-509.
2005: Berry Karin A Zemski; Murphy Robert C
Analysis of cell membrane aminophospholipids as isotope-tagged derivatives.
Journal of lipid research 2005;46(5):1038-46.
2005: Zemski Berry Karin A; Murphy Robert C
Free radical oxidation of plasmalogen glycerophosphocholine containing esterified docosahexaenoic acid: structure determination by mass spectrometry.
Antioxidants & redox signaling 2005;7(1-2):157-69.
2005: Zhang Qiwei; Southall Michael D; Mezsick Steven M; Johnson Christopher; Murphy Robert C; Konger Raymond L; Travers Jeffrey B
Epidermal peroxisome proliferator-activated receptor gamma as a target for ultraviolet B radiation.
The Journal of biological chemistry 2005;280(1):73-9.
2005: Piboonpocanun Surapon; Chiba Hirofumi; Mitsuzawa Hiroaki; Martin Wesley; Murphy Robert C; Harbeck Ronald J; Voelker Dennis R
Surfactant protein A binds Mycoplasma pneumoniae with high affinity and attenuates its growth by recognition of disaturated phosphatidylglycerols.
The Journal of biological chemistry 2005;280(1):9-17.
2005: Blaine Stacy A; Meyer Amy M; Hurteau Greg; Wick Marilee; Hankin Joseph A; Murphy Robert C; Dannenberg Andrew J; Geraci Mark W; Subbaramaiah Kotha; Nemenoff Raphael A
Targeted over-expression of mPGES-1 and elevated PGE2 production is not sufficient for lung tumorigenesis in mice.
Carcinogenesis 2005;26(1):209-17.
2005: Pulfer Melissa K; Taube Christian; Gelfand Erwin; Murphy Robert C
Ozone exposure in vivo and formation of biologically active oxysterols in the lung.
The Journal of pharmacology and experimental therapeutics 2005;312(1):256-64.
2004: Nick Jerry A; Coldren Christopher D; Geraci Mark W; Poch Katie R; Fouty Brian W; O'Brien James; Gruber Michael; Zarini Simona; Murphy Robert C; Kuhn Katherine; Richter Don; Kast Kelly R; Abraham Edward
Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis.
Blood 2004;104(13):3878-85.
2004: Zimmer Jennifer S Dickinson; Dyckes Douglas F; Bernlohr David A; Murphy Robert C
Fatty acid binding proteins stabilize leukotriene A4: competition with arachidonic acid but not other lipoxygenase products.
Journal of lipid research 2004;45(11):2138-44.
2004: Zemski Berry Karin A; Murphy Robert C
Electrospray ionization tandem mass spectrometry of glycerophosphoethanolamine plasmalogen phospholipids.
Journal of the American Society for Mass Spectrometry 2004;15(10):1499-508.
2004: Hankin Joseph A; Murphy Robert C
Mass spectrometric quantitation of deoxyguanosine and leukotriene A4-deoxyguanosine adducts of DNA.
Analytical biochemistry 2004;333(1):156-64.
2004: Choi Jae-Yeon; Martin Wesley E; Murphy Robert C; Voelker Dennis R
Phosphatidylcholine and N-methylated phospholipids are nonessential in Saccharomyces cerevisiae.
The Journal of biological chemistry 2004;279(40):42321-30.
2004: Fessler Michael B; Arndt Patrick G; Frasch S Courtney; Lieber Jonathan G; Johnson Christopher A; Murphy Robert C; Nick Jerry A; Bratton Donna L; Malcolm Kenneth C; Worthen G Scott
Lipid rafts regulate lipopolysaccharide-induced activation of Cdc42 and inflammatory functions of the human neutrophil.
The Journal of biological chemistry 2004;279(38):39989-98.
2004: Pulfer Melissa K; Murphy Robert C
Formation of biologically active oxysterols during ozonolysis of cholesterol present in lung surfactant.
The Journal of biological chemistry 2004;279(25):26331-8.
2004: Di Gennaro Antonio; Carnini Chiara; Buccellati Carola; Ballerio Rossana; Zarini Simona; Fumagalli Francesca; Viappiani Serena; Librizzi Laura; Hernandez Alicia; Murphy Robert C; Constantin Gabriela; De Curtis Marco; Folco Giancarlo; Sala Angelo
Cysteinyl-leukotrienes receptor activation in brain inflammatory reactions and cerebral edema formation: a role for transcellular biosynthesis of cysteinyl-leukotrienes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(7):842-4.
2004: Pulfer Melissa K; Harrison Kathleen; Murphy Robert C
Direct electrospray tandem mass spectrometry of the unstable hydroperoxy bishemiacetal product derived from cholesterol ozonolysis.
Journal of the American Society for Mass Spectrometry 2004;15(2):194-202.
2004: Dickinson Zimmer Jennifer S; Voelker Dennis R; Bernlohr David A; Murphy Robert C
Stabilization of leukotriene A4 by epithelial fatty acid-binding protein in the rat basophilic leukemia cell.
The Journal of biological chemistry 2004;279(9):7420-6.
2004: Ghosh Moumita; Stewart Allison; Tucker Dawn E; Bonventre Joseph V; Murphy Robert C; Leslie Christina C
Role of cytosolic phospholipase A(2) in prostaglandin E(2) production by lung fibroblasts.
American journal of respiratory cell and molecular biology 2004;30(1):91-100.
2003: Pulfer Melissa; Murphy Robert C
Electrospray mass spectrometry of phospholipids.
Mass spectrometry reviews 2003;22(5):332-64.
2003: Watanabe Junji; Marathe Gopal K; Neilsen Paul O; Weyrich Andrew S; Harrison Kathleen A; Murphy Robert C; Zimmerman Guy A; McIntyre Thomas M
Endotoxins stimulate neutrophil adhesion followed by synthesis and release of platelet-activating factor in microparticles.
The Journal of biological chemistry 2003;278(35):33161-8.
2003: Berry Karin A Zemski; Borgeat Pierre; Gosselin Jean; Flamand Louis; Murphy Robert C
Urinary metabolites of leukotriene B4 in the human subject.
The Journal of biological chemistry 2003;278(27):24449-60.
2003: Liu Yingfang; Hong Xia; Kappler John; Jiang Ling; Zhang Rongguang; Xu Liangguo; Pan Cheol-Ho; Martin Wesley E; Murphy Robert C; Shu Hong-Bing; Dai Shaodong; Zhang Gongyi
Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature 2003;423(6935):49-56.
2003: Hankin Joseph A; Jones David N M; Murphy Robert C
Covalent binding of leukotriene A4 to DNA and RNA.
Chemical research in toxicology 2003;16(4):551-61.
2003: Zarini Simona; Murphy Robert C
Biosynthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid from 5-hydroperoxyeicosatetraenoic acid in the murine macrophage.
The Journal of biological chemistry 2003;278(13):11190-6.
2003: Hankin Joseph A; Murphy Robert C
Covalent binding of leukotriene A4 to nucleosides, nucleotides, and nucleic acids.
Advances in experimental medicine and biology 2003;525():29-33.
2002: Stonehouse Martin J; Cota-Gomez Adela; Parker Sarah K; Martin Wesley E; Hankin Joseph A; Murphy Robert C; Chen Weibin; Lim Kheng B; Hackett Murray; Vasil Adriana I; Vasil Michael L
A novel class of microbial phosphocholine-specific phospholipases C.
Molecular microbiology 2002;46(3):661-76.
2002: Dickinson Jennifer S; Murphy Robert C
Mass spectrometric analysis of leukotriene A4 and other chemically reactive metabolites of arachidonic acid.
Journal of the American Society for Mass Spectrometry 2002;13(10):1227-34.
2002: Wilderman Paula J; Vasil Adriana I; Martin Wesley E; Murphy Robert C; Vasil Michael L
Pseudomonas aeruginosa synthesizes phosphatidylcholine by use of the phosphatidylcholine synthase pathway.
Journal of bacteriology 2002;184(17):4792-9.
2002: Murphy Robert C; Zarini Simona
Glutathione adducts of oxyeicosanoids.
Prostaglandins & other lipid mediators 2002;68-69():471-82.
2002: Uhlson Charis; Harrison Kathleen; Allen Corrie B; Ahmad Shama; White Carl W; Murphy Robert C
Oxidized phospholipids derived from ozone-treated lung surfactant extract reduce macrophage and epithelial cell viability.
Chemical research in toxicology 2002;15(7):896-906.
2002: Petersen Jeffrey E; Hiran Tejindervir S; Goebel W Scott; Johnson Christopher; Murphy Robert C; Azmi Farrukh H; Hood Antoinette F; Travers Jeffrey B; Dinauer Mary C
Enhanced cutaneous inflammatory reactions to Aspergillus fumigatus in a murine model of chronic granulomatous disease.
The Journal of investigative dermatology 2002;118(3):424-9.
2002: Hevko John M; Murphy Robert C
Formation of murine macrophage-derived 5-oxo-7-glutathionyl-8,11,14-eicosatrienoic acid (FOG7) is catalyzed by leukotriene C4 synthase.
The Journal of biological chemistry 2002;277(9):7037-43.
2001: Bauer A K; Dwyer-Nield L D; Hankin J A; Murphy R C; Malkinson A M
The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice.
Toxicology 2001;169(1):1-15.
2001: Storey M K; Clay K L; Kutateladze T; Murphy R C; Overduin M; Voelker D R
Phosphatidylethanolamine has an essential role in Saccharomyces cerevisiae that is independent of its ability to form hexagonal phase structures.
The Journal of biological chemistry 2001;276(51):48539-48.
2001: Fiedler J; Simon F R; Iwahashi M; Murphy R C
Effect of peroxisome proliferator-activated receptor alpha activation on leukotriene B4 metabolism in isolated rat hepatocytes.
The Journal of pharmacology and experimental therapeutics 2001;299(2):691-7.
2001: Hevko J M; Murphy R C
Electrospray ionization and tandem mass spectrometry of cysteinyl eicosanoids: leukotriene C4 and FOG7.
Journal of the American Society for Mass Spectrometry 2001;12(7):763-71.
2001: Murphy R C
Free-radical-induced oxidation of arachidonoyl plasmalogen phospholipids: antioxidant mechanism and precursor pathway for bioactive eicosanoids.
Chemical research in toxicology 2001;14(5):463-72.
2001: Davies S S; Pontsler A V; Marathe G K; Harrison K A; Murphy R C; Hinshaw J C; Prestwich G D; Hilaire A S; Prescott S M; Zimmerman G A; McIntyre T M
Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists.
The Journal of biological chemistry 2001;276(19):16015-23.
2001: Marathe G K; Harrison K A; Roberts L J; Morrow J D; Murphy R C; Tjoelker L W; Prescott S M; Zimmerman G A; McIntyre T M
Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver.
Journal of lipid research 2001;42(4):587-96.
2001: Murphy R C; Fiedler J; Hevko J
Analysis of nonvolatile lipids by mass spectrometry.
Chemical reviews 2001;101(2):479-526.
2001: Hevko J M; Bowers R C; Murphy R C
Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid and identification of novel omega-oxidized metabolites in the mouse macrophage.
The Journal of pharmacology and experimental therapeutics 2001;296(2):293-305.
2000: Khaselev N; Murphy R C
Peroxidation of arachidonate containing plasmenyl glycerophosphocholine: facile oxidation of esterified arachidonate at carbon-5.
Free radical biology & medicine 2000;29(7):620-32.
2000: Bowers R C; Hevko J; Henson P M; Murphy R C
A novel glutathione containing eicosanoid (FOG7) chemotactic for human granulocytes.
The Journal of biological chemistry 2000;275(39):29931-4.
2000: Reiber D C; Murphy R C
Covalent binding of LTA(4) to nucleosides and nucleotides.
Archives of biochemistry and biophysics 2000;379(1):119-26.
2000: Marathe G K; Harrison K A; Murphy R C; Prescott S M; Zimmerman G A; McIntyre T M
Bioactive phospholipid oxidation products.
Free radical biology & medicine 2000;28(12):1762-70.
2000: Khaselev N; Murphy R C
Electrospray ionization mass spectrometry of lysoglycerophosphocholine lipid subclasses.
Journal of the American Society for Mass Spectrometry 2000;11(4):283-91.
2000: Khaselev N; Murphy R C
Structural characterization of oxidized phospholipid products derived from arachidonate-containing plasmenyl glycerophosphocholine.
Journal of lipid research 2000;41(4):564-72.
2000: Harrison K A; Davies S S; Marathe G K; McIntyre T; Prescott S; Reddy K M; Falck J R; Murphy R C
Analysis of oxidized glycerophosphocholine lipids using electrospray ionization mass spectrometry and microderivatization techniques.
Journal of mass spectrometry : JMS 2000;35(2):224-36.
2000: Hankin J A; Murphy R C
The metabolism of leukotriene B4 in Lewis lung carcinoma porcine kidney cells.
American journal of respiratory and critical care medicine 2000;161(2 Pt 2):S81-7.
1999: Marathe G K; Davies S S; Harrison K A; Silva A R; Murphy R C; Castro-Faria-Neto H; Prescott S M; Zimmerman G A; McIntyre T M
Inflammatory platelet-activating factor-like phospholipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines.
The Journal of biological chemistry 1999;274(40):28395-404.
1999: Sala A; Zarini S; Folco G; Murphy R C; Henson P M
Differential metabolism of exogenous and endogenous arachidonic acid in human neutrophils.
The Journal of biological chemistry 1999;274(40):28264-9.
1999: Murphy R C; Khaselev N; Nakamura T; Hall L M
Oxidation of glycerophospholipids from biological membranes by reactive oxygen species: liquid chromatographic-mass spectrometric analysis of eicosanoid products.
Journal of chromatography. B, Biomedical sciences and applications 1999;731(1):59-71.
1999: Harrison K A; Clay K L; Murphy R C
Negative ion electrospray and tandem mass spectrometric analysis of platelet activating factor (PAF) (1-hexadecyl-2-acetyl-glycerophosphocholine).
Journal of mass spectrometry : JMS 1999;34(4):330-5.
1999: Khaselev N; Murphy R C
Susceptibility of plasmenyl glycerophosphoethanolamine lipids containing arachidonate to oxidative degradation.
Free radical biology & medicine 1999;26(3-4):275-84.
1999: Wheelan P; Hankin J A; Bilir B; Guenette D; Murphy R C
Metabolic transformations of leukotriene B4 in primary cultures of human hepatocytes.
The Journal of pharmacology and experimental therapeutics 1999;288(1):326-34.
1999: Nakamura T; Hall L; Murphy R C
Oxidation of arachidonate containing glycerophospholipids in intact red blood cells and red blood cell membranes with tert-butylhydroperoxide.
Advances in experimental medicine and biology 1999;469():539-45.
1998: Fiedler J; Wheelan P; Henson P M; Murphy R C
Exogenous leukotriene B4 (LTB4) inhibits human neutrophil generation of LTB4 from endogenous arachidonic acid during opsonized zymosan phagocytosis.
The Journal of pharmacology and experimental therapeutics 1998;287(1):150-6.
1998: Hall L M; Murphy R C
Activation of human polymorphonuclear leukocytes by products derived from the peroxidation of human red blood cell membranes.
Chemical research in toxicology 1998;11(9):1024-31.
1998: Travers J B; Murphy R C; Johnson C A; Pei Y; Morin S M; Clay K L; Barber L A; Hood A F; Morelli J G; Williams D A
Identification and pharmacological characterization of platelet-activating factor and related 1-palmitoyl species in human inflammatory blistering diseases.
Prostaglandins & other lipid mediators 1998;56(5-6):305-24.
1998: Nakamura T; Henson P M; Murphy R C
Occurrence of oxidized metabolites of arachidonic acid esterified to phospholipids in murine lung tissue.
Analytical biochemistry 1998;262(1):23-32.
1998: Pei Y; Barber L A; Murphy R C; Johnson C A; Kelley S W; Dy L C; Fertel R H; Nguyen T M; Williams D A; Travers J B
Activation of the epidermal platelet-activating factor receptor results in cytokine and cyclooxygenase-2 biosynthesis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1954-61.
1998: Barber L A; Spandau D F; Rathman S C; Murphy R C; Johnson C A; Kelley S W; Hurwitz S A; Travers J B
Expression of the platelet-activating factor receptor results in enhanced ultraviolet B radiation-induced apoptosis in a human epidermal cell line.
The Journal of biological chemistry 1998;273(30):18891-7.
1998: Hall L M; Murphy R C
Electrospray mass spectrometric analysis of 5-hydroperoxy and 5-hydroxyeicosatetraenoic acids generated by lipid peroxidation of red blood cell ghost phospholipids.
Journal of the American Society for Mass Spectrometry 1998;9(5):527-32.
1998: Hall L M; Murphy R C
Analysis of stable oxidized molecular species of glycerophospholipids following treatment of red blood cell ghosts with t-butylhydroperoxide.
Analytical biochemistry 1998;258(2):184-94.
1998: Hankin J A; Clay C E; Murphy R C
The effects of ethanol and acetaldehyde on the metabolism of prostaglandin E2 and leukotriene B4 in isolated rat hepatocytes.
The Journal of pharmacology and experimental therapeutics 1998;285(1):155-61.
1997: Nakamura T; Bratton D L; Murphy R C
Analysis of epoxyeicosatrienoic and monohydroxyeicosatetraenoic acids esterified to phospholipids in human red blood cells by electrospray tandem mass spectrometry.
Journal of mass spectrometry : JMS 1997;32(8):888-96.
1997: Travers J B; Johnson C; Clay K L; Harrison K; Zekman T; Morelli J G; Murphy R C
Identification of sn-2 acetyl glycerophosphocholines in human keratinocytes.
Journal of lipid mediators and cell signalling 1997;16(3):139-45.
1997: Hankin J A; Wheelan P; Murphy R C
Identification of novel metabolites of prostaglandin E2 formed by isolated rat hepatocytes.
Archives of biochemistry and biophysics 1997;340(2):317-30.
1997: Sala A; Folco G; Henson P M; Murphy R C
Pharmacological modulation of human platelet leukotriene C4-synthase.
Biochemical pharmacology 1997;53(6):905-8.
1997: Wheelan P; Murphy R C
Quantitation of 5-lipoxygenase products by electrospray mass spectrometry: effect of ethanol on zymosan-stimulated production of 5-lipoxygenase products by human neutrophils.
Analytical biochemistry 1997;244(1):110-5.
1997: Waugh R J; Morrow J D; Roberts L J; Murphy R C
Identification and relative quantitation of F2-isoprostane regioisomers formed in vivo in the rat.
Free radical biology & medicine 1997;23(6):943-54.
1996: Wheelan P; Murphy R C; Simon F R
Gas chromatographic/mass spectrometric analysis of oxo and chain-shortened leukotriene B4 metabolites. Leukotriene B4 metabolism in Ito cells.
Journal of mass spectrometry : JMS 1996;31(3):236-46.
1995: Travers J B; Huff J C; Rola-Pleszczynski M; Gelfand E W; Morelli J G; Murphy R C
Identification of functional platelet-activating factor receptors on human keratinocytes.
The Journal of investigative dermatology 1995;105(6):816-23.
1995: Wheelan P; Murphy R C
Metabolism of 6-trans-isomers of leukotriene B4 in cultured hepatoma cells and in human polymorphonuclear leukocytes. Identification of a delta 6-reductase metabolic pathway.
The Journal of biological chemistry 1995;270(34):19845-52.
1995: Wheelan P; Murphy R C
Metabolism of leukotriene B4 in cultured hepatoma cells.
Archives of biochemistry and biophysics 1995;321(2):381-9.
1995: Harrison K A; Murphy R C
Isoleukotrienes are biologically active free radical products of lipid peroxidation.
The Journal of biological chemistry 1995;270(29):17273-8.
1995: Hill E; MacMillan D; Sala A; Henson P M; Murphy R C
Properties of LTA4 synthase in human neutrophil preparations.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():155-7.
1994: Wheelan P; Sala A; Folco G; Nicosia S; Falck J R; Bhatt R K; Murphy R C
Stereochemical analysis and biological activity of 3-hydroxy-leukotriene B4: a metabolite from ethanol-treated rat hepatocytes.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1514-9.
1994: Wheelan P; Travers J B; Morelli J G; Murphy R C
Metabolism of leukotriene B4 (LTB4) and 12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HETE) in human keratinocytes.
Annals of the New York Academy of Sciences 1994;744():39-49.
1994: MacMillan D K; Hill E; Sala A; Sigal E; Shuman T; Henson P M; Murphy R C
Eosinophil 15-lipoxygenase is a leukotriene A4 synthase.
The Journal of biological chemistry 1994;269(43):26663-8.
1994: Kayganich-Harrison K A; Murphy R C
Incorporation of stable isotope-labeled arachidonic acid into cellular phospholipid molecular species and analysis by fast atom bombardment tandem mass spectrometry.
Biological mass spectrometry 1994;23(9):562-71.
1994: Kayganich-Harrison K A; Murphy R C
Characterization of chain-shortened oxidized glycerophosphocholine lipids using fast atom bombardment and tandem mass spectrometry.
Analytical biochemistry 1994;221(1):16-24.
1994: Murphy R C; FitzGerald G A
Current approaches to estimation of eicosanoid formation in vivo.
Advances in prostaglandin, thromboxane, and leukotriene research 1994;22():341-8.
1993: Wheelan P; Zirrolli J A; Morelli J G; Murphy R C
Metabolism of leukotriene B4 by cultured human keratinocytes. Formation of glutathione conjugates and dihydro metabolites.
The Journal of biological chemistry 1993;268(34):25439-48.
1993: Wheelan P; Zirrolli J A; Murphy R C
Low-energy fast atom bombardment tandem mass spectrometry of monohydroxy substituted unsaturated fatty acids.
Biological mass spectrometry 1993;22(8):465-73.
1993: Kayganich-Harrison K A; Rose D M; Murphy R C; Morrow J D; Roberts L J
Collision-induced dissociation of F2-isoprostane-containing phospholipids.
Journal of lipid research 1993;34(7):1229-35.
1993: Fruteau de Laclos B; Zirrolli J A; Murphy R C
Collision-induced dissociation of carboxylate anions from derivatized 5-lipoxygenase metabolites of arachidonic acid.
Biological mass spectrometry 1993;22(1):9-18.
1992: Kayganich K A; Murphy R C
Fast atom bombardment tandem mass spectrometric identification of diacyl, alkylacyl, and alk-1-enylacyl molecular species of glycerophosphoethanolamine in human polymorphonuclear leukocytes.
Analytical chemistry 1992;64(23):2965-71.
1992: Hill E; Maclouf J; Murphy R C; Henson P M
Reversible membrane association of neutrophil 5-lipoxygenase is accompanied by retention of activity and a change in substrate specificity.
The Journal of biological chemistry 1992;267(31):22048-53.
1992: Antoine C; Murphy R C; Henson P M; Maclouf J
Time-dependent utilization of platelet arachidonic acid by the neutrophil in formation of 5-lipoxygenase products in platelet-neutrophil co-incubations.
Biochimica et biophysica acta 1992;1128(2-3):139-46.
1992: Hill E; Fitzpatrick F; Murphy R C
Biological activity and metabolism of 20-hydroxyeicosatetraenoic acid in the human platelet.
British journal of pharmacology 1992;106(2):267-74.
1992: Shirley M A; Reidhead C T; Murphy R C
Chemotactic LTB4 metabolites produced by hepatocytes in the presence of ethanol.
Biochemical and biophysical research communications 1992;185(2):604-10.
1992: Hill E; Murphy R C
Quantitation of 20-hydroxy-5,8,11,14-eicosatetraenoic acid (20-HETE) produced by human polymorphonuclear leukocytes using electron capture ionization gas chromatography/mass spectrometry.
Biological mass spectrometry 1992;21(5):249-53.
1992: Voelkel N F; Czartolomna J; Simpson J; Murphy R C
FMLP causes eicosanoid-dependent vasoconstriction and edema in lungs from endotoxin-primed rats.
The American review of respiratory disease 1992;145(3):701-11.
1992: Bernstrom K; Kayganich K; Murphy R C; Fitzpatrick F A
Incorporation and distribution of epoxyeicosatrienoic acids into cellular phospholipids.
The Journal of biological chemistry 1992;267(6):3686-90.
1992: Morelli J G; Hake S S; Murphy R C; Norris D A
Leukotriene B4-induced human melanocyte pigmentation and leukotriene C4-induced human melanocyte growth are inhibited by different isoquinolinesulfonamides.
The Journal of investigative dermatology 1992;98(1):55-8.
1991: Zirrolli J A; Clay K L; Murphy R C
Tandem mass spectrometry of negative ions from choline phospholipid molecular species related to platelet activating factor.
Lipids 1991;26(12):1112-6.
1991: Nishimura M; Schwartzman M L; Falck J R; Lumin S; Zirrolli J A; Murphy R C
Metabolism of 12(R)-hydroxy-5,8,10,14-eicosatetraenoic acid (12(R)-HETE) in corneal tissues: formation of novel metabolites.
Archives of biochemistry and biophysics 1991;290(2):326-35.
1991: Bernstrom K; Kayganich K; Murphy R C
Collisionally induced dissociation of epoxyeicosatrienoic acids and epoxyeicosatrienoic acid-phospholipid molecular species.
Analytical biochemistry 1991;198(1):203-11.
1991: Sala A; Murphy R C; Voelkel N F
Direct airway injury results in elevated levels of sulfidopeptide leukotrienes, detectable in airway secretions.
Prostaglandins 1991;42(1):1-7.
1991: Carroll M A; Sala A; Dunn C E; McGiff J C; Murphy R C
Structural identification of cytochrome P450-dependent arachidonate metabolites formed by rabbit medullary thick ascending limb cells.
The Journal of biological chemistry 1991;266(19):12306-12.
1991: Schwartzman M L; Davis K L; Nishimura M; Abraham N G; Murphy R C
The cytochrome P450 metabolic pathway of arachidonic acid in the cornea.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():185-92.
1991: Sala A; Voelkel N; Maclouf J; Murphy R C
Metabolism of radioisotopic variants of LTE4 in human subjects and excretion of urinary metabolites.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():177-80.
1991: Murphy R C; Maclouf J; Henson P M
Interaction of platelets and neutrophils in the generation of sulfidopeptide leukotrienes.
Advances in experimental medicine and biology 1991;314():91-101.
1991: Murphy R C; Sala A; Voelkel N; Maclouf J
Appearance of urinary metabolites of LTE4 in human subjects.
Annals of the New York Academy of Sciences 1991;629():105-11.
1990: Sala A; Voelkel N; Maclouf J; Murphy R C
Leukotriene E4 elimination and metabolism in normal human subjects.
The Journal of biological chemistry 1990;265(35):21771-8.
1990: Shirley M A; Murphy R C
Metabolism of leukotriene B4 in isolated rat hepatocytes. Involvement of 2,4-dienoyl-coenzyme A reductase in leukotriene B4 metabolism.
The Journal of biological chemistry 1990;265(27):16288-95.
1990: Morelli J G; Norris D A; Lyons M B; Murphy R C
Metabolism of exogenous leukotrienes by cultured human keratinocytes.
The Journal of investigative dermatology 1990;94(5):681-4.
1990: Miadonna A; Tedeschi A; Brasca C; Folco G; Sala A; Murphy R C
Mediator release after endobronchial antigen challenge in patients with respiratory allergy.
The Journal of allergy and clinical immunology 1990;85(5):906-13.
1990: Bettazzoli L; Zirrolli J A; Reidhead C T; Shahgholi M; Murphy R C
Incorporation of arachidonic acid into glycerophospholipids of a murine bone marrow derived mast cell.
Advances in prostaglandin, thromboxane, and leukotriene research 1990;20():71-8.
1989: Morelli J G; Yohn J J; Lyons M B; Murphy R C; Norris D A
Leukotrienes C4 and D4 as potent mitogens for cultured human neonatal melanocytes.
The Journal of investigative dermatology 1989;93(6):719-22.
1989: Fradin A; Zirrolli J A; Maclouf J; Vausbinder L; Henson P M; Murphy R C
Platelet-activating factor and leukotriene biosynthesis in whole blood. A model for the study of transcellular arachidonate metabolism.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(11):3680-5.
1989: Maclouf J; Murphy R C; Henson P M
Transcellular sulfidopeptide leukotriene biosynthetic capacity of vascular cells.
Blood 1989;74(2):703-7.
1989: Chang S W; Westcott J Y; Pickett W C; Murphy R C; Voelkel N F
Endotoxin-induced lung injury in rats: role of eicosanoids.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;66(5):2407-18.
1989: Masferrer J L; Murphy R C; Pagano P J; Dunn M W; Laniado-Schwartzman M
Ocular effects of a novel cytochrome P-450-dependent arachidonic acid metabolite.
Investigative ophthalmology & visual science 1989;30(3):454-60.
1989: Masferrer J L; Murphy R C; Abraham N G; Laniado-Schwartzman M
Corneal arachidonate metabolism via cytochrome P450: characterization of two novel biologically active metabolites.
Advances in prostaglandin, thromboxane, and leukotriene research 1989;19():351-4.
1989: Stene D O; Murphy R C
Sequential formation of leukotriene E4 metabolites by isolated rat hepatocytes.
Advances in prostaglandin, thromboxane, and leukotriene research 1989;19():108-11.
1988: Fitzpatrick F A; Murphy R C
Cytochrome P-450 metabolism of arachidonic acid: formation and biological actions of "epoxygenase"-derived eicosanoids.
Pharmacological reviews 1988;40(4):229-41.
1988: Murphy R C; Falck J R; Lumin S; Yadagiri P; Zirrolli J A; Balazy M; Masferrer J L; Abraham N G; Schwartzman M L
12(R)-hydroxyeicosatrienoic acid: a vasodilator cytochrome P-450-dependent arachidonate metabolite from the bovine corneal epithelium.
The Journal of biological chemistry 1988;263(32):17197-202.
1988: Santoro T J; Morris D H; Murphy R C; Baker R C
Aberrant production of leukotriene C4 by macrophages from autoimmune-prone mice.
The Journal of experimental medicine 1988;168(2):783-8.
1988: Hadley J S; Fradin A; Murphy R C
Electron capture negative ion chemical ionization analysis of arachidonic acid.
Biomedical & environmental mass spectrometry 1988;15(3):175-8.
1988: Stene D O; Murphy R C
Metabolism of leukotriene E4 in isolated rat hepatocytes. Identification of beta-oxidation products of sulfidopeptide leukotrienes.
The Journal of biological chemistry 1988;263(6):2773-8.
1988: Maclouf J A; Murphy R C
Transcellular metabolism of neutrophil-derived leukotriene A4 by human platelets. A potential cellular source of leukotriene C4.
The Journal of biological chemistry 1988;263(1):174-81.
1988: Murphy R C; Stene D O
Oxidative metabolism of leukotriene E4 by rat hepatocytes.
Annals of the New York Academy of Sciences 1988;524():35-42.
1987: Westcott J Y; Murphy R C; Stenmark K
Eicosanoids in human ventricular cerebrospinal fluid following severe brain injury.
Prostaglandins 1987;34(6):877-87.
1987: Schwartzman M L; Balazy M; Masferrer J; Abraham N G; McGiff J C; Murphy R C
12(R)-hydroxyicosatetraenoic acid: a cytochrome-P450-dependent arachidonate metabolite that inhibits Na+,K+-ATPase in the cornea.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(22):8125-9.
1987: Haroldsen P E; Murphy R C
Analysis of phospholipid molecular species in rat lung as dinitrobenzoate diglycerides by electron capture negative chemical ionization mass spectrometry.
Biomedical & environmental mass spectrometry 1987;14(10):573-8.

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