FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Sharon Murphy

Research Profile

Chemicals & Drugs

Activities & Behaviors

Phenomena

Hydroxylation

Concepts & Ideas

Anatomy

Procedures

High Pressure Liquid Chromatography

Disorders

Lung Neoplasms

Co-author Network

Publications

TOP 3
Dorothy K Hatsukami; Stephen J Heishman; Joni Jensen; Kristen M Mackowick; Sharon E Murphy; Astia N Roper-Batker; Brian F Thomas; Rachel Isaksson Vogel; Rachel L Denlinger; Eric C Donny
Dose-response effects of spectrum research cigarettes.
A Joseph Bloom; Oscar Harari; Maribel Martinez; Sandra A McDonald; Sharon E Murphy; Xiaochun Zhang; Alison Goate
A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
A Joseph Bloom; Maribel Martinez; Sharon E Murphy; Linda B von Weymarn; Laura J Bierut; Alison Goate
Effects upon in-vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Sharon Murphy (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Dorothy K Hatsukami; Stephen J Heishman; Joni Jensen; Kristen M Mackowick; Sharon E Murphy; Astia N Roper-Batker; Brian F Thomas; Rachel Isaksson Vogel; Rachel L Denlinger; Eric C Donny
Dose-response effects of spectrum research cigarettes.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2013;15(6):1113-21.
2013: A Joseph Bloom; Oscar Harari; Maribel Martinez; Sandra A McDonald; Sharon E Murphy; Xiaochun Zhang; Alison Goate
A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
Pharmacogenetics and genomics 2013;23(3):107-16.
2013: A Joseph Bloom; Maribel Martinez; Sharon E Murphy; Linda B von Weymarn; Laura J Bierut; Alison Goate
Effects upon in-vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption.
Pharmacogenetics and genomics 2013;23(2):62-8.
2012: Linda B von Weymarn; Cassandra Retzlaff; Sharon E Murphy
CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ion.
The Journal of pharmacology and experimental therapeutics 2012;343(2):307-15.
2012: Valerie M Kramlinger; Linda B von Weymarn; Sharon E Murphy
Inhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and menthol.
Chemico-biological interactions 2012;197(2-3):87-92.
2011: Joseph Bloom; Alison Goate; Anthony L Hinrichs; Evan D Kharasch; Linda B von Weymarn; Jen C Wang; Laura J Bierut; Sharon E Murphy
The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans.
Pharmacogenetics and genomics 2011;21(7):403-16.
2011: Michael Kotlyar; Louise A Hertsgaard; Bruce R Lindgren; Joni A Jensen; Steven G Carmella; Irina Stepanov; Sharon E Murphy; Stephen S Hecht; Dorothy K Hatsukami
Effect of oral snus and medicinal nicotine in smokers on toxicant exposure and withdrawal symptoms: a feasibility study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011;20(1):91-100.
2010: Dorothy K Hatsukami; Michael Kotlyar; Louise A Hertsgaard; Yan Zhang; Steven G Carmella; Joni A Jensen; Sharon S Allen; Peter G Shields; Sharon E Murphy; Irina Stepanov; Stephen S Hecht
Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation.
Addiction (Abingdon, England) 2010;105(2):343-55.
2010: Janet L Thomas; Lawrence C An; Xianghua Luo; Robyn M Scherber; Carla J Berg; Dave Golden; Edward P Ehlinger; Sharon E Murphy; Stephen S Hecht; Jasjit S Ahluwalia
Abstinence and relapse rates following a college campus-based quit & win contest.
Journal of American college health : J of ACH 2010;58(4):365-72.
2010: Jeannette Zinggeler Berg; Jesse Mason; Angela J Boettcher; Dorothy K Hatsukami; Sharon E Murphy
Nicotine metabolism in African Americans and European Americans: variation in glucuronidation by ethnicity and UGT2B10 haplotype.
The Journal of pharmacology and experimental therapeutics 2010;332(1):202-9.
2009: Kiersten S Derby; Kristine Cuthrell; Christian Caberto; Steven Carmella; Sharon E Murphy; Stephen S Hecht; Loïc Le Marchand
Exposure to the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers from 3 populations with different risks of lung cancer.
International journal of cancer. Journal international du cancer 2009;125(10):2418-24.
2009: Jian-Min Yuan; Woon-Puay Koh; Sharon E Murphy; Yunhua Fan; Renwei Wang; Steven G Carmella; Shaomei Han; Katie Wickham; Yu-Tang Gao; Mimi C Yu; Stephen S Hecht
Urinary levels of tobacco-specific nitrosamine metabolites in relation to lung cancer development in two prospective cohorts of cigarette smokers.
Cancer research 2009;69(7):2990-5.
2009: Kari E Schlicht; Jeannette Zinggeler Berg; Sharon E Murphy
Effect of CYP2A13 active site mutation N297A on metabolism of coumarin and tobacco-specific nitrosamines.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(3):665-71.
2008: Louise A Hertsgaard; Karen Hanson; Stephen S Hecht; Bruce R Lindgren; Xianghua Luo; Steven G Carmella; William T Riley; Emily B Zylla; Sharon E Murphy; Dorothy K Hatsukami
Exposure to a tobacco-specific lung carcinogen in adolescent versus adult smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(12):3337-43.
2008: Loïc Le Marchand; Kiersten S Derby; Sharon E Murphy; Stephen S Hecht; Dorothy Hatsukami; Steven G Carmella; Maarit Tiirikainen; Hansong Wang
Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine.
Cancer research 2008;68(22):9137-40.
2008: Marc E Mooney; Zhong-Ze Li; Sharon E Murphy; Paul R Pentel; Chap Le; Dorothy K Hatsukami
Stability of the nicotine metabolite ratio in ad libitum and reducing smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(6):1396-400.
2008: Stephen S Hecht; Steven G Carmella; A Edmonds; Sharon E Murphy; Irina Stepanov; X Luo; Dorothy K Hatsukami
Exposure to nicotine and a tobacco-specific carcinogen increase with duration of use of smokeless tobacco.
Tobacco control 2008;17(2):128-31.
2007: K E Schlicht; N Michno; B D Smith; E E Scott; Sharon E Murphy
Functional characterization of CYP2A13 polymorphisms.
Xenobiotica; the fate of foreign compounds in biological systems 2007;37(12):1439-49.
2007: Dorothy K Hatsukami; Anne M Joseph; Mark Lesage; Joni Jensen; Sharon E Murphy; Paul R Pentel; Michael Kotlyar; Eugene Borgida; Chap Le; Stephen S Hecht
Developing the science base for reducing tobacco harm.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2007;9 Suppl 4():S537-53.
2007: Sharon E Murphy; Peter W Villalta; Sing-Wei Ho; Linda B von Weymarn
Analysis of [3',3'-d(2)]-nicotine and [3',3'-d(2)]-cotinine by capillary liquid chromatography-electrospray tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;857(1):1-8.
2007: Stephen S Hecht; Steven G Carmella; Sharon E Murphy; William T Riley; Chap Le; Xianghua Luo; Marc Mooney; Dorothy K Hatsukami
Similar exposure to a tobacco-specific carcinogen in smokeless tobacco users and cigarette smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(8):1567-72.
2006: Stephen S Hecht; Steven G Carmella; Ky-Anh Le; Sharon E Murphy; Angela J Boettcher; Chap Le; Joseph Koopmeiners; Lawrence C An; Deborah J Hennrikus
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronides in the urine of infants exposed to environmental tobacco smoke.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(5):988-92.
2006: Linda B von Weymarn; Kathryn M Brown; Sharon E Murphy
Inactivation of CYP2A6 and CYP2A13 during nicotine metabolism.
The Journal of pharmacology and experimental therapeutics 2006;316(1):295-303.
2005: Anne M Joseph; Stephen S Hecht; Sharon E Murphy; Steven G Carmella; Chap T Le; Yan Zhang; Shaomei Han; Dorothy K Hatsukami
Relationships between cigarette consumption and biomarkers of tobacco toxin exposure.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(12):2963-8.
2005: Kathryn M Brown; Linda B von Weymarn; Sharon E Murphy
Identification of N-(hydroxymethyl) norcotinine as a major product of cytochrome P450 2A6, but not cytochrome P450 2A13-catalyzed cotinine metabolism.
Chemical research in toxicology 2005;18(12):1792-8.
2005: Kari E Dicke; Sara M Skrlin; Sharon E Murphy
Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-butanone metabolism by cytochrome P450 2B6.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(12):1760-4.
2005: Sharon E Murphy; Vytautas Raulinaitis; Kathryn M Brown
Nicotine 5'-oxidation and methyl oxidation by P450 2A enzymes.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(8):1166-73.
2005: Charlotte A Lemmonds; Stephen S Hecht; Joni A Jensen; Sharon E Murphy; Steven G Carmella; Yan Zhang; Dorothy K Hatsukami
Smokeless tobacco topography and toxin exposure.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2005;7(3):469-74.
2005: Hansen L Wong; Xiuling Zhang; Qing-Yu Zhang; Jun Gu; Xinxin Ding; Stephen S Hecht; Sharon E Murphy
Metabolic activation of the tobacco carcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone by cytochrome P450 2A13 in human fetal nasal microsomes.
Chemical research in toxicology 2005;18(6):913-8.
2005: Stephen S Hecht; Sharon E Murphy; Steven G Carmella; Shelby Li; Joni Jensen; Chap Le; Anne M Joseph; Dorothy K Hatsukami
Similar uptake of lung carcinogens by smokers of regular, light, and ultralight cigarettes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(3):693-8.
2005: Hansen L Wong; Sharon E Murphy; Stephen S Hecht
Cytochrome P450 2A-catalyzed metabolic activation of structurally similar carcinogenic nitrosamines: N'-nitrosonornicotine enantiomers, N-nitrosopiperidine, and N-nitrosopyrrolidine.
Chemical research in toxicology 2005;18(1):61-9.
2004: Sharon E Murphy; Carrie A Link; Joni Jensen; Chap Le; Susan Puumala; Stephen S Hecht; Steven G Carmella; London Losey; Dorothy K Hatsukami
A comparison of urinary biomarkers of tobacco and carcinogen exposure in smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(10):1617-23.
2004: Dorothy K Hatsukami; Charlotte A Lemmonds; Yan Zhang; Sharon E Murphy; Chap Le; Steven G Carmella; Stephen S Hecht
Evaluation of carcinogen exposure in people who used "reduced exposure" tobacco products.
Journal of the National Cancer Institute 2004;96(11):844-52.
2004: John R Hughes; Stephen S Hecht; Steven G Carmella; Sharon E Murphy; Peter W Callas
Smoking behaviour and toxin exposure during six weeks use of a potential reduced exposure product: Omni.
Tobacco control 2004;13(2):175-9.
2004: Stephen S Hecht; Steven G Carmella; Ky-Anh Le; Sharon E Murphy; Y Shelby Li; Chap Le; Joni Jensen; Dorothy K Hatsukami
Effects of reduced cigarette smoking on levels of 1-hydroxypyrene in urine.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(5):834-42.
2004: Stephen S Hecht; Sharon E Murphy; Steven G Carmella; Cheryl L Zimmerman; London Losey; Irene Kramarczuk; Mikel R Roe; Susan Puumala; Y Shelby Li; Chap Le; Joni Jensen; Dorothy K Hatsukami
Effects of reduced cigarette smoking on the uptake of a tobacco-specific lung carcinogen.
Journal of the National Cancer Institute 2004;96(2):107-15.
2003: Kristin E Anderson; Jen Kliris; Lois Murphy; Steven G Carmella; Shaomei Han; Carrie Link; Robin L Bliss; Susan Puumala; Sharon E Murphy; Stephen S Hecht
Metabolites of a tobacco-specific lung carcinogen in nonsmoking casino patrons.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(12):1544-6.
2003: Gwendolyn E Kuehl; Sharon E Murphy
N-glucuronidation of trans-3'-hydroxycotinine by human liver microsomes.
Chemical research in toxicology 2003;16(12):1502-6.
2003: Gwendolyn E Kuehl; Sharon E Murphy
N-glucuronidation of nicotine and cotinine by human liver microsomes and heterologously expressed UDP-glucuronosyltransferases.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(11):1361-8.
2003: Hansen L Wong; Sharon E Murphy; Stephen S Hecht
Preferential metabolic activation of N-nitrosopiperidine as compared to its structural homologue N-nitrosopyrrolidine by rat nasal mucosal microsomes.
Chemical research in toxicology 2003;16(10):1298-305.
2003: Hansen L Wong; Sharon E Murphy; Mingyao Wang; Stephen S Hecht
Comparative metabolism of N-nitrosopiperidine and N-nitrosopyrrolidine by rat liver and esophageal microsomes and cytochrome P450 2A3.
Carcinogenesis 2003;24(2):291-300.
2003: Linda B von Weymarn; Sharon E Murphy
CYP2A13-catalysed coumarin metabolism: comparison with CYP2A5 and CYP2A6.
Xenobiotica; the fate of foreign compounds in biological systems 2003;33(1):73-81.
2001: Linda B von Weymarn; Sharon E Murphy
Coumarin metabolism by rat esophageal microsomes and cytochrome P450 2A3.
Chemical research in toxicology 2001;14(10):1386-92.
2001: Sharon E Murphy; L M Johnson; London Losey; Steven G Carmella; Stephen S Hecht
Consumption of watercress fails to alter coumarin metabolism in humans.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(6):786-8.
2000: N D Felicia; G K Rekha; Sharon E Murphy
Characterization of cytochrome P450 2A4 and 2A5-catalyzed 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism.
Archives of biochemistry and biophysics 2000;384(2):418-24.
2000: Stephen S Hecht; J Bradley Hochalter; Peter W Villalta; Sharon E Murphy
2'-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: formation of a lung carcinogen precursor.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12493-7.
1999: Linda B von Weymarn; N D Felicia; Xinxin Ding; Sharon E Murphy
N-Nitrosobenzylmethylamine hydroxylation and coumarin 7-hydroxylation: catalysis by rat esophageal microsomes and cytochrome P450 2A3 and 2A6 enzymes.
Chemical research in toxicology 1999;12(12):1254-61.
1999: Stephen S Hecht; Steven G Carmella; Sharon E Murphy
Effects of watercress consumption on urinary metabolites of nicotine in smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(10):907-13.
1999: Sharon E Murphy; L M Johnson; D A Pullo
Characterization of multiple products of cytochrome P450 2A6-catalyzed cotinine metabolism.
Chemical research in toxicology 1999;12(7):639-45.
1999: Stephen S Hecht; Steven G Carmella; Menglan Chen; J F Dor Koch; A T Miller; Sharon E Murphy; Joni A Jensen; Cheryl L Zimmerman; Dorothy K Hatsukami
Quantitation of urinary metabolites of a tobacco-specific lung carcinogen after smoking cessation.
Cancer research 1999;59(3):590-6.