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Judith Murray-Rust

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Svend Kjær; Phillip P Knowles; Brenda Kostelecky; Mark Linch; Caroline Barton; Christian Dillon; Sarah Kaye; Judith Murray-Rust; Peter J Parker; Bhavisha Patel; Andrew Purkiss; Philippe Riou; Jon Roffey; Carine Rosse; Erika Soriano; Christelle Soudy; Neil Q McDonald
Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes.
Batiste Boëda; Phillip P Knowles; David Briggs; Judith Murray-Rust; Erika Soriano; Boyan K Garvalov; Neil Q McDonald; Michael Way
Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A.
Lila Mayahi; Lydia Mason; Katherine Bleasdale-Barr; Ann Donald; Iris Trender-Gerhard; Mary G Sweeney; Mary B Davis; Nicholas Wood; Christopher J Mathias; Laura Watson; Denis Pellerin; Simon Heales; John E Deanfield; Kailash Bhatia; Judith Murray-Rust; Aroon D Hingorani
Endothelial, sympathetic, and cardiac function in inherited (6R)-L-erythro-5,6,7,8-tetrahydro-L-biopterin deficiency.

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All Publications

2013: Svend Kjær; Phillip P Knowles; Brenda Kostelecky; Mark Linch; Caroline Barton; Christian Dillon; Sarah Kaye; Judith Murray-Rust; Peter J Parker; Bhavisha Patel; Andrew Purkiss; Philippe Riou; Jon Roffey; Carine Rosse; Erika Soriano; Christelle Soudy; Neil Q McDonald
Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes.
The Biochemical journal 2013;451(2):329-42.
2011: Batiste Boëda; Phillip P Knowles; David Briggs; Judith Murray-Rust; Erika Soriano; Boyan K Garvalov; Neil Q McDonald; Michael Way
Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A.
The Journal of biological chemistry 2011;286(13):11543-54.
2010: Lila Mayahi; Lydia Mason; Katherine Bleasdale-Barr; Ann Donald; Iris Trender-Gerhard; Mary G Sweeney; Mary B Davis; Nicholas Wood; Christopher J Mathias; Laura Watson; Denis Pellerin; Simon Heales; John E Deanfield; Kailash Bhatia; Judith Murray-Rust; Aroon D Hingorani
Endothelial, sympathetic, and cardiac function in inherited (6R)-L-erythro-5,6,7,8-tetrahydro-L-biopterin deficiency.
Circulation. Cardiovascular genetics 2010;3(6):513-22.
2010: Luca Mologni; Roberta Rostagno; Stefania Brussolo; Phillip P Knowles; Svend Kjaer; Judith Murray-Rust; Enrico Rosso; Alfonso Zambon; Leonardo Scapozza; Neil McDonald; Vittorio Lucchini; Carlo Gambacorti-Passerini
Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors.
Bioorganic & medicinal chemistry 2010;18(4):1482-96.
2008: Sadaf Shadan; Roman Holic; Nicolas Carvou; Patrick Ee; Michelle Li; Judith Murray-Rust; Shamshad Cockcroft
Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells.
Traffic (Copenhagen, Denmark) 2008;9(10):1743-56.
2008: Rebecca Kirk; Heike Laman; Philip P Knowles; Judith Murray-Rust; Mikhail Lomonosov; El Kahina Meziane; Neil McDonald
Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor.
The Journal of biological chemistry 2008;283(32):22325-35.
2007: James M Leiper; Manasi Nandi; Belen Torondel; Judith Murray-Rust; Mohammed Malaki; Bernard O'Hara; Sharon Rossiter; Shelagh Anthony; Melanie Madhani; David L Selwood; Caroline Smith; Beata Wojciak-Stothard; Alain Rudiger; Ray Stidwill; Neil McDonald; Patrick Vallance
Disruption of methylarginine metabolism impairs vascular homeostasis.
Nature medicine 2007;13(2):198-203.
2006: Philip P Knowles; Judith Murray-Rust; Svend Kjaer; Rizaldy P Scott; Sarah Hanrahan; Massimo Santoro; Carlos F Ibáñez; Neil McDonald
Structure and chemical inhibition of the RET tyrosine kinase domain.
The Journal of biological chemistry 2006;281(44):33577-87.
2005: Matthew Newman; Judith Murray-Rust; John Lally; Jana Rudolf; Andrew Fadden; Philip P Knowles; Malcolm White; Neil McDonald
Structure of an XPF endonuclease with and without DNA suggests a model for substrate recognition.
The EMBO journal 2005;24(5):895-905.
2004: Clive P Morgan; Alison Skippen; Bruno Segui; Andrew Ball; Victoria Allen-Baume; Banafshé Larijani; Judith Murray-Rust; Neil McDonald; Gopal P Sapkota; Nick Morrice; Shamshad Cockcroft
Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes.
The Journal of biological chemistry 2004;279(45):47159-71.
2004: John Lally; Matthew Newman; Judith Murray-Rust; Andrew Fadden; Yutaka Kawarabayasi; Neil McDonald
Crystallization of the xeroderma pigmentosum group F endonuclease from Aeropyrum pernix.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 9):1658-61.
2004: Sarah J Tilley; Alison Skippen; Judith Murray-Rust; Philip Swigart; Albert Stewart; Clive P Morgan; Shamshad Cockcroft; Neil McDonald
Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol.
Structure (London, England : 1993) 2004;12(2):317-26.
2004: Farahnaz Movahedzadeh; Debbie A Smith; Richard A Norman; Premkumar Dinadayala; Judith Murray-Rust; David G Russell; Sharon L Kendall; Stuart C G Rison; Mark S B McAlister; Gregory J Bancroft; Neil McDonald; Mamadou Daffe; Yossef Av-Gay; neil stoker
The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence.
Molecular microbiology 2004;51(4):1003-14.
2004: Peter J Parker; Judith Murray-Rust
PKC at a glance.
Journal of cell science 2004;117(Pt 2):131-2.
2002: James M Leiper; Judith Murray-Rust; Neil McDonald; Patrick Vallance
S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13527-32.
2002: Richard A Norman; Mark S B McAlister; Judith Murray-Rust; Farahnaz Movahedzadeh; neil stoker; Neil McDonald
Crystal structure of inositol 1-phosphate synthase from Mycobacterium tuberculosis, a key enzyme in phosphatidylinositol synthesis.
Structure (London, England : 1993) 2002;10(3):393-402.
2001: Judith Murray-Rust; James M Leiper; Mark S B McAlister; J Phelan; S Tilley; J Santa Maria; Patrick Vallance; Neil McDonald
Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase.
Nature structural biology 2001;8(8):679-83.
2001: Gert De Wilde; Judith Murray-Rust; Elke Boone; D Olerenshaw; Neil McDonald; C Ibanez; Guy Haegeman; Axel Wollmer; M Federwisch
Structure-activity relationship of the p55 TNF receptor death domain and its lymphoproliferation mutants.
European journal of biochemistry / FEBS 2001;268(5):1382-91.
1999: Susanna Eketjäll; Mike Fainzilber; Judith Murray-Rust; Carlos F Ibáñez
Distinct structural elements in GDNF mediate binding to GFRalpha1 and activation of the GFRalpha1-c-Ret receptor complex.
The EMBO journal 1999;18(21):5901-10.
1998: H Pappa; Judith Murray-Rust; Lodewijk Dekker; Peter J Parker; Neil McDonald
Crystal structure of the C2 domain from protein kinase C-delta.
Structure (London, England : 1993) 1998;6(7):885-94.
1997: B Bax; Tom L Blundell; Judith Murray-Rust; Neil McDonald
Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins.
Structure (London, England : 1993) 1997;5(10):1275-85.
1996: R Gill; B Wallach; C Verma; Birgitte Uraø; E De Wolf; Joachim Grötzinger; Judith Murray-Rust; J Pitts; Axel Wollmer; Pierre De Meyts; S Wood
Engineering the C-region of human insulin-like growth factor-1: implications for receptor binding.
Protein engineering 1996;9(11):1011-9.
1995: M Rydén; Judith Murray-Rust; D Glass; Leodevico L Ilag; M Trupp; George D Yancopoulos; N Q McDonald; Carlos F Ibáñez
Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling.
The EMBO journal 1995;14(9):1979-90.
1995: Neil McDonald; Judith Murray-Rust; Tom L Blundell
The first structure of a receptor tyrosine kinase domain: a further step in understanding the molecular basis of insulin action.
Structure (London, England : 1993) 1995;3(1):1-6.
1994: Ralph A Bradshaw; Judith Murray-Rust; Carlos F Ibáñez; N Q McDonald; R Lapatto; Tom L Blundell
Nerve growth factor: structure/function relationships.
Protein science : a publication of the Protein Society 1994;3(11):1901-13.
1993: Judith Murray-Rust; Neil McDonald; Tom L Blundell; M Hosang; Christian Oefner; F Winkler; R A Bradshaw
Topological similarities in TGF-beta 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors.
Structure (London, England : 1993) 1993;1(2):153-9.
1993: Carlos F Ibáñez; Leodevico L Ilag; Judith Murray-Rust; H Persson
An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin.
The EMBO journal 1993;12(6):2281-93.
1993: Ralph A Bradshaw; Tom L Blundell; R Lapatto; N Q McDonald; Judith Murray-Rust
Nerve growth factor revisited.
Trends in biochemical sciences 1993;18(2):48-52.
1993: Judith Murray-Rust
Do specific interactions between transmembrane helices play a part in signalling transduction? Exploration with the insulin receptor.
BioEssays : news and reviews in molecular, cellular and developmental biology 1993;15(1):61-2.
1992: Judith Murray-Rust; A N McLeod; Tom L Blundell; Steve P Wood
Structure and evolution of insulins: implications for receptor binding.
BioEssays : news and reviews in molecular, cellular and developmental biology 1992;14(5):325-31.
1992: Carlos F Ibáñez; Ted Ebendal; G Barbany; Judith Murray-Rust; Tom L Blundell; H Persson
Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product.
Cell 1992;69(2):329-41.
1991: Neil McDonald; R Lapatto; Judith Murray-Rust; J Gunning; A Wlodawer; Tom L Blundell
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor.
Nature 1991;354(6352):411-4.
1990: Neil McDonald; R Lapatto; Judith Murray-Rust; Tom L Blundell
X-ray crystallographic studies on murine nerve growth factor.
Journal of cell science. Supplement 1990;13():19-30.