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Alain Bélanger

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Sophie Pâquet; Paul S Rennie; Bernard Têtu; Mélanie Verreault; Alain Bélanger; Ladan Fazli; Laurent Grosse; Olivier Barbier
Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.
Étienne Audet-Walsh; Johanie Lépine; Jean Grégoire; Marie Plante; Patrick Caron; Bernard Têtu; Pierre Ayotte; Jacques Brisson; Lyne Villeneuve; Alain Bélanger; Chantal Guillemette
Profiling of endogenous estrogens, their precursors, and metabolites in endometrial cancer patients: association with risk and relationship to clinical characteristics.
Johanie Lépine; Étienne Audet-Walsh; Jean Grégoire; Bernard Têtu; Marie Plante; Vincent Menard; Pierre Ayotte; Jacques Brisson; Patrick Caron; Lyne Villeneuve; Alain Bélanger; Chantal Guillemette
Circulating estrogens in endometrial cancer cases and their relationship with tissular expression of key estrogen biosynthesis and metabolic pathways.

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2012: Sophie Pâquet; Paul S Rennie; Bernard Têtu; Mélanie Verreault; Alain Bélanger; Ladan Fazli; Laurent Grosse; Olivier Barbier
Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.
The Journal of clinical endocrinology and metabolism 2012;97(3):E428-32.
2011: Étienne Audet-Walsh; Johanie Lépine; Jean Grégoire; Marie Plante; Patrick Caron; Bernard Têtu; Pierre Ayotte; Jacques Brisson; Lyne Villeneuve; Alain Bélanger; Chantal Guillemette
Profiling of endogenous estrogens, their precursors, and metabolites in endometrial cancer patients: association with risk and relationship to clinical characteristics.
The Journal of clinical endocrinology and metabolism 2011;96(2):E330-9.
2010: Johanie Lépine; Étienne Audet-Walsh; Jean Grégoire; Bernard Têtu; Marie Plante; Vincent Menard; Pierre Ayotte; Jacques Brisson; Patrick Caron; Lyne Villeneuve; Alain Bélanger; Chantal Guillemette
Circulating estrogens in endometrial cancer cases and their relationship with tissular expression of key estrogen biosynthesis and metabolic pathways.
The Journal of clinical endocrinology and metabolism 2010;95(6):2689-98.
2009: Patrick Caron; Étienne Audet-Walsh; Johanie Lépine; Alain Bélanger; Chantal Guillemette
Profiling endogenous serum estrogen and estrogen-glucuronides by liquid chromatography-tandem mass spectrometry.
Analytical chemistry 2009;81(24):10143-8.
2009: Fernand Labrie; Leonello Cusan; José Luis Gomez; Céline Martel; René Bérubé; Patrick Bélanger; Alain Bélanger; Liesbeth Vandenput; Dan Mellström; Claes Ohlsson
Comparable amounts of sex steroids are made outside the gonads in men and women: strong lesson for hormone therapy of prostate and breast cancer.
The Journal of steroid biochemistry and molecular biology 2009;113(1-2):52-6.
2008: Olivier Barbier; Alain Bélanger
Inactivation of androgens by UDP-glucuronosyltransferases in the human prostate.
Best practice & research. Clinical endocrinology & metabolism 2008;22(2):259-70.
2008: Van Luu-The; Alain Bélanger; Fernand Labrie
Androgen biosynthetic pathways in the human prostate.
Best practice & research. Clinical endocrinology & metabolism 2008;22(2):207-21.
2008: Sarah Chouinard; Mei-Fei Yueh; Robert H Tukey; Frank Giton; Jean Fiet; Georges Pelletier; Olivier Barbier; Alain Bélanger
Inactivation by UDP-glucuronosyltransferase enzymes: the end of androgen signaling.
The Journal of steroid biochemistry and molecular biology 2008;109(3-5):247-53.
2008: Jenny Kaeding; Emmanuel Bouchaert; Julie Bélanger; Patrick Caron; Sarah Chouinard; Mélanie Verreault; Olivier Larouche; Georges Pelletier; Bart Staels; Alain Bélanger; Olivier Barbier
Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.
The Biochemical journal 2008;410(2):245-53.
2008: Jenny Kaeding; Julie Bélanger; Patrick Caron; Mélanie Verreault; Alain Bélanger; Olivier Barbier
Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells.
Molecular cancer therapeutics 2008;7(2):380-90.
2007: Sarah Chouinard; Olivier Barbier; Alain Bélanger
UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.
The Journal of biological chemistry 2007;282(46):33466-74.
2007: Fernand Labrie; Alain Bélanger; Claude Labrie; Bernard Candas; Leonello Cusan; José Luis Gomez
Bioavailability and metabolism of oral and percutaneous dehydroepiandrosterone in postmenopausal women.
The Journal of steroid biochemistry and molecular biology 2007;107(1-2):57-69.
2007: Bertrand Caillier; Johanie Lépine; Jelena Tojcic; Vincent Menard; Louis Perusse; Alain Bélanger; Olivier Barbier; Chantal Guillemette
A pharmacogenomics study of the human estrogen glucuronosyltransferase UGT1A3.
Pharmacogenetics and genomics 2007;17(7):481-95.
2007: Fernand Labrie; Alain Bélanger; Patrick Bélanger; René Bérubé; Céline Martel; Leonello Cusan; José Gomez; Bernard Candas; Véronique Chaussade; Isabelle Castiel; Claire Deloche; Jacques Leclaire
Metabolism of DHEA in postmenopausal women following percutaneous administration.
The Journal of steroid biochemistry and molecular biology 2007;103(2):178-88.
2006: Sarah Chouinard; Georges Pelletier; Alain Bélanger; Olivier Barbier
Isoform-specific regulation of uridine diphosphate-glucuronosyltransferase 2B enzymes in the human prostate: differential consequences for androgen and bioactive lipid inactivation.
Endocrinology 2006;147(11):5431-42.
2006: Fernand Labrie; Alain Bélanger; Patrick Bélanger; René Bérubé; Céline Martel; Leonello Cusan; José Gomez; Bernard Candas; Isabelle Castiel; Véronique Chaussade; Claire Deloche; Jacques Leclaire
Androgen glucuronides, instead of testosterone, as the new markers of androgenic activity in women.
The Journal of steroid biochemistry and molecular biology 2006;99(4-5):182-8.
2006: Sarah Chouinard; Mélanie Tessier; Gabrielle Vernouillet; Sylvain Gauthier; Fernand Labrie; Olivier Barbier; Alain Bélanger
Inactivation of the pure antiestrogen fulvestrant and other synthetic estrogen molecules by UDP-glucuronosyltransferase 1A enzymes expressed in breast tissue.
Molecular pharmacology 2006;69(3):908-20.
2006: Jean Thibaudeau; Johanie Lépine; Jelena Tojcic; Yannick Duguay; Georges Pelletier; Marie Plante; Jacques Brisson; Bernard Têtu; Simon Jacob; Louis Perusse; Alain Bélanger; Chantal Guillemette
Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone.
Cancer research 2006;66(1):125-33.
2005: Fernand Labrie; Van Luu-The; Alain Bélanger; Sheng-Xiang Lin; Jacques Simard; Georges Pelletier; Claude Labrie
Is dehydroepiandrosterone a hormone?
The Journal of endocrinology 2005;187(2):169-96.
2005: Fernand Labrie; Alain Bélanger; Van Luu-The; Claude Labrie; Jacques Simard; Leonello Cusan; José Gomez; Bernard Candas
Gonadotropin-releasing hormone agonists in the treatment of prostate cancer.
Endocrine reviews 2005;26(3):361-79.
2004: Fernand Labrie; Leonello Cusan; José Gomez; Van Luu-The; Bernard Candas; Alain Bélanger; Claude Labrie
Major impact of hormonal therapy in localized prostate cancer--death can already be an exception.
The Journal of steroid biochemistry and molecular biology 2004;92(5):327-44.
2004: Sarah Chouinard; Georges Pelletier; Alain Bélanger; Olivier Barbier
Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium.
Endocrine research 2004;30(4):717-25.
2004: Johanie Lépine; Olivier Bernard; Marie Plante; Bernard Têtu; Georges Pelletier; Fernand Labrie; Alain Bélanger; Chantal Guillemette
Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium.
The Journal of clinical endocrinology and metabolism 2004;89(10):5222-32.
2004: Fernand Labrie; Bernard Candas; Leonello Cusan; José Luis Gomez; Alain Bélanger; Ghyslain Brousseau; Eric Chevrette; Jacques Lévesque
Screening decreases prostate cancer mortality: 11-year follow-up of the 1988 Quebec prospective randomized controlled trial.
The Prostate 2004;59(3):311-8.
2004: Mathias Leblanc; Marie-Claire Bélanger; Pierre Julien; André Tchernof; Claude Labrie; Alain Bélanger; Fernand Labrie
Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal, and combined androgen blockade conditions.
The Journal of clinical endocrinology and metabolism 2004;89(4):1849-57.
2004: Yannick Duguay; Monica McGrath; Johanie Lépine; Jean-François Gagné; Susan E Hankinson; GRaham Colditz; David J Hunter; Marie Plante; Bernard Têtu; Alain Bélanger; Chantal Guillemette; Immaculata DeVivo
The functional UGT1A1 promoter polymorphism decreases endometrial cancer risk.
Cancer research 2004;64(3):1202-7.
2004: Chantal Guillemette; Alain Bélanger; Johanie Lépine
Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview.
Breast cancer research : BCR 2004;6(6):246-54.
2003: Alain Bélanger; Georges Pelletier; Fernand Labrie; Olivier Barbier; Sarah Chouinard
Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.
Trends in endocrinology and metabolism: TEM 2003;14(10):473-9.
2003: david sullivan; Alain Bélanger; Jennifer M Cermak; René Bérubé; Athena S Papas; Rose Sullivan; Hiroko Yamagami; M Reza Dana; Fernand Labrie
Are women with Sjögren's syndrome androgen-deficient?
The Journal of rheumatology 2003;30(11):2413-9.
2003: Fernand Labrie; Mohamed El-Alfy; Louise Berger; Claude Labrie; Céline Martel; Alain Bélanger; Bernard Candas; Georges Pelletier
The combination of a novel selective estrogen receptor modulator with an estrogen protects the mammary gland and uterus in a rodent model: the future of postmenopausal women's health?
Endocrinology 2003;144(11):4700-6.
2003: Fernand Labrie; Leonello Cusan; José Luis Gomez; Bernard Candas; Alain Bélanger; Van Luu-The; Claude Labrie; Jacques Simard
[From the gene to the clinic: prostate cancer death can now be an exception?].
Médecine sciences : M/S 2003;19(10):910-9.
2003: Mathias Leblanc; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Bioavailability and pharmacokinetics of dehydroepiandrosterone in the cynomolgus monkey.
The Journal of clinical endocrinology and metabolism 2003;88(9):4293-302.
2003: Olivier Barbier; Alain Bélanger
The cynomolgus monkey (Macaca fascicularis) is the best animal model for the study of steroid glucuronidation.
The Journal of steroid biochemistry and molecular biology 2003;85(2-5):235-45.
2003: Caroline Girard; Olivier Barbier; Guy Veilleux; Mohamed El-Alfy; Alain Bélanger
Human uridine diphosphate-glucuronosyltransferase UGT2B7 conjugates mineralocorticoid and glucocorticoid metabolites.
Endocrinology 2003;144(6):2659-68.
2003: David Turgeon; Jean-Sébastien Carrier; Sarah Chouinard; Alain Bélanger
Glucuronidation activity of the UGT2B17 enzyme toward xenobiotics.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(5):670-6.
2003: Fernand Labrie; Van Luu-The; Claude Labrie; Alain Bélanger; Jacques Simard; Sheng-Xiang Lin; Georges Pelletier
Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone.
Endocrine reviews 2003;24(2):152-82.
2002: Caroline Girard; Olivier Barbier; David Turgeon; Alain Bélanger
Isolation and characterization of the monkey UGT2B30 gene that encodes a uridine diphosphate-glucuronosyltransferase enzyme active on mineralocorticoid, glucocorticoid, androgen and oestrogen hormones.
The Biochemical journal 2002;365(Pt 1):213-22.
2002: Mathias Leblanc; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Pharmacokinetics of oral dehydroepiandrosterone (DHEA) in the ovariectomised cynomolgus monkey.
The Journal of steroid biochemistry and molecular biology 2002;81(2):159-64.
2001: Fernand Labrie; Claude Labrie; Alain Bélanger; Jacques Simard; V Giguère; A Tremblay; G Tremblay
EM-652 (SCH57068), a pure SERM having complete antiestrogenic activity in the mammary gland and endometrium.
The Journal of steroid biochemistry and molecular biology 2001;79(1-5):213-25.
2001: Georges Pelletier; Songyun Li; Van Luu-The; Y Tremblay; Alain Bélanger; Fernand Labrie
Immunoelectron microscopic localization of three key steroidogenic enzymes (cytochrome P450(scc), 3 beta-hydroxysteroid dehydrogenase and cytochrome P450(c17)) in rat adrenal cortex and gonads.
The Journal of endocrinology 2001;171(2):373-83.
2001: Jacques R Rouleau; Anne Dagnault; Denis Simard; Bernard Lavallée; Alain Bélanger; André Blouin; John G Kingma
Effect of estrogen replacement therapy on distribution of myocardial blood flow in female anesthetized rabbits.
American journal of physiology. Heart and circulatory physiology 2001;281(3):H1407-12.
2001: Marie-Hélène Vallée; C Albert; G Beaudry; Dean W Hum; Alain Bélanger
Isolation and characterization of the monkey UDP-glucuronosyltransferase cDNA clone monUGT1A01 active on bilirubin and estrogens.
The Journal of steroid biochemistry and molecular biology 2001;77(4-5):239-49.
2001: Olivier Barbier; Caroline Girard; Louise Berger; Mohamed El-Alfy; Alain Bélanger; Dean W Hum
The androgen-conjugating uridine diphosphoglucuronosyltransferase-2B enzymes are differentially expressed temporally and spatially in the monkey follicle throughout the menstrual cycle.
Endocrinology 2001;142(6):2499-507.
2001: Eric Lévesque; David Turgeon; Jean-Sébastien Carrier; Valerie Montminy; M Beaulieu; Alain Bélanger
Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase.
Biochemistry 2001;40(13):3869-81.
2001: Olivier Barbier; C Albert; Isabelle Martineau; Marie-Hélène Vallée; K High; Fernand Labrie; Dean W Hum; Claude Labrie; Alain Bélanger
Glucuronidation of the nonsteroidal antiestrogen EM-652 (SCH 57068), by human and monkey steroid conjugating UDP-glucuronosyltransferase enzymes.
Molecular pharmacology 2001;59(3):636-45.
2001: David Turgeon; Jean-Sébastien Carrier; Eric Lévesque; Dean W Hum; Alain Bélanger
Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members.
Endocrinology 2001;142(2):778-87.
2001: Fernand Labrie; Claude Labrie; Alain Bélanger; V Giguere; Jacques Simard; Yves Mérand; Sylvain Gauthier; Van Luu-The; Bernard Candas; Céline Martel; S Luo
Pure selective estrogen receptor modulators, new molecules having absolute cell specificity ranging from pure antiestrogenic to complete estrogen-like activities.
Advances in protein chemistry 2001;56():293-368.
2000: Olivier Barbier; H Lapointe; Mohamed El-Alfy; Dean W Hum; Alain Bélanger
Cellular localization of uridine diphosphoglucuronosyltransferase 2B enzymes in the human prostate by in situ hybridization and immunohistochemistry.
The Journal of clinical endocrinology and metabolism 2000;85(12):4819-26.
2000: Olivier Barbier; Caroline Girard; Rock Breton; Alain Bélanger; Dean W Hum
N-glycosylation and residue 96 are involved in the functional properties of UDP-glucuronosyltransferase enzymes.
Biochemistry 2000;39(38):11540-52.
2000: Bernard Candas; Leonello Cusan; José Luis Gomez; Pierre Diamond; RE Suburu; Jacques Lévesque; Ghyslain Brousseau; Alain Bélanger; Fernand Labrie
Evaluation of prostatic specific antigen and digital rectal examination as screening tests for prostate cancer.
The Prostate 2000;45(1):19-35.
2000: Fernand Labrie; Van Luu-The; Sheng-Xiang Lin; Jacques Simard; Claude Labrie; Mohamed El-Alfy; Georges Pelletier; Alain Bélanger
Intracrinology: role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease.
Journal of molecular endocrinology 2000;25(1):1-16.
2000: C Albert; Olivier Barbier; Marie-Hélène Vallée; G Beaudry; Alain Bélanger; Dean W Hum
Distribution of uridine diphosphate-glucuronosyltransferase (UGT) expression and activity in cynomolgus monkey tissues: evidence for differential expression of steroid-conjugating UGT enzymes in steroid target tissues.
Endocrinology 2000;141(7):2472-80.
2000: Jean-Sébastien Carrier; David Turgeon; K Journault; Dean W Hum; Alain Bélanger
Isolation and characterization of the human UGT2B7 gene.
Biochemical and biophysical research communications 2000;272(2):616-21.
2000: Pascale Mauriège; Dominique Langin; Valerie Montminy; C Martel; J P Després; Alain Bélanger; F Labrie; Y Deshaies
Effect of a long-term percutaneous adrenal steroid treatment on rat adipose tissue metabolism.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24 Suppl 2():S148-50.
2000: Olivier Barbier; David Turgeon; Caroline Girard; M D Green; Thomas R Tephly; Dean W Hum; Alain Bélanger
3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7).
Drug metabolism and disposition: the biological fate of chemicals 2000;28(5):497-502.
2000: David Turgeon; Jean-Sébastien Carrier; Eric Lévesque; Barbara G Beatty; Alain Bélanger; Dean W Hum
Isolation and characterization of the human UGT2B15 gene, localized within a cluster of UGT2B genes and pseudogenes on chromosome 4.
Journal of molecular biology 2000;295(3):489-504.
1999: Olivier Barbier; Eric Lévesque; Alain Bélanger; Dean W Hum
UGT2B23, a novel uridine diphosphate-glucuronosyltransferase enzyme expressed in steroid target tissues that conjugates androgen and estrogen metabolites.
Endocrinology 1999;140(12):5538-48.
1999: C Albert; Marie-Hélène Vallée; G Beaudry; Alain Bélanger; Dean W Hum
The monkey and human uridine diphosphate-glucuronosyltransferase UGT1A9, expressed in steroid target tissues, are estrogen-conjugating enzymes.
Endocrinology 1999;140(7):3292-302.
1999: SG Dubois; M Beaulieu; Eric Lévesque; Dean W Hum; Alain Bélanger
Alteration of human UDP-glucuronosyltransferase UGT2B17 regio-specificity by a single amino acid substitution.
Journal of molecular biology 1999;289(1):29-39.
1999: André Tchernof; Eric Lévesque; M Beaulieu; P Couture; J P Després; Dean W Hum; Alain Bélanger
Expression of the androgen metabolizing enzyme UGT2B15 in adipose tissue and relative expression measurement using a competitive RT-PCR method.
Clinical endocrinology 1999;50(5):637-42.
1999: Dean W Hum; Alain Bélanger; Eric Lévesque; Olivier Barbier; M Beaulieu; C Albert; Marie-Hélène Vallée; Chantal Guillemette; André Tchernof; David Turgeon; SG Dubois
Characterization of UDP-glucuronosyltransferases active on steroid hormones.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):413-23.
1999: Fernand Labrie; Claude Labrie; Alain Bélanger; Jacques Simard; Sylvain Gauthier; Van Luu-The; Yves Mérand; V Giguere; Bernard Candas; S Luo; Céline Martel; SM Singh; M Fournier; A Coquet; V Richard; R Charbonneau; G Charpenet; A Tremblay; G Tremblay; Leonello Cusan; R Veilleux
EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):51-84.
1999: Eric Lévesque; M Beaulieu; Dean W Hum; Alain Bélanger
Characterization and substrate specificity of UGT2B4 (E458): a UDP-glucuronosyltransferase encoded by a polymorphic gene.
Pharmacogenetics 1999;9(2):207-16.
1999: Geoffroy Bélanger; Olivier Barbier; Dean W Hum; Alain Bélanger
Molecular cloning, expression and characterization of a monkey steroid UDP-glucuronosyltransferase, UGT2B19, that conjugates testosterone.
European journal of biochemistry / FEBS 1999;260(3):701-8.
1999: Olivier Barbier; Alain Bélanger; Dean W Hum
Cloning and characterization of a simian UDP-glucuronosyltransferase enzyme UGT2B20, a novel C19 steroid-conjugating protein.
The Biochemical journal 1999;337 ( Pt 3)():567-74.
1998: Claude Beaudoin; Bernard Lavallée; Yves Tremblay; Dean W Hum; Rock Breton; Y de Launoit; Alain Bélanger
Modulation of 17alpha-hydroxylase/17,20-lyase activity of guinea pig cytochrome P450c17 by site-directed mutagenesis.
DNA and cell biology 1998;17(8):707-15.
1998: M Beaulieu; Eric Lévesque; Dean W Hum; Alain Bélanger
Isolation and characterization of a human orphan UDP-glucuronosyltransferase, UGT2B11.
Biochemical and biophysical research communications 1998;248(1):44-50.
1998: Steeve Couillard; Claude Labrie; Alain Bélanger; Bernard Candas; Frédéric Pouliot; Fernand Labrie
Effect of dehydroepiandrosterone and the antiestrogen EM-800 on growth of human ZR-75-1 breast cancer xenografts.
Journal of the National Cancer Institute 1998;90(10):772-8.
1998: S Luo; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Prevention of development of dimethylbenz(a)anthracene (DMBA)-induced mammary tumors in the rat by the new nonsteroidal antiestrogen EM-800 (SCH57050).
Breast cancer research and treatment 1998;49(1):1-11.
1998: Fernand Labrie; Alain Bélanger; Van Luu-The; Claude Labrie; Jacques Simard; Leonello Cusan; José Luis Gomez; Bernard Candas
DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging.
Steroids 1998;63(5-6):322-8.
1998: Céline Martel; Claude Labrie; Alain Bélanger; Sylvain Gauthier; Yves Mérand; X Li; Louise Provencher; Bernard Candas; Fernand Labrie
Comparison of the effects of the new orally active antiestrogen EM-800 with ICI 182 780 and toremifene on estrogen-sensitive parameters in the ovariectomized mouse.
Endocrinology 1998;139(5):2486-92.
1998: Eric Lévesque; M Beaulieu; Chantal Guillemette; Dean W Hum; Alain Bélanger
Effect of interleukins on UGT2B15 and UGT2B17 steroid uridine diphosphate-glucuronosyltransferase expression and activity in the LNCaP cell line.
Endocrinology 1998;139(5):2375-81.
1998: Alain Bélanger; Dean W Hum; M Beaulieu; Eric Lévesque; Chantal Guillemette; André Tchernof; Geoffroy Bélanger; David Turgeon; SG Dubois
Characterization and regulation of UDP-glucuronosyltransferases in steroid target tissues.
The Journal of steroid biochemistry and molecular biology 1998;65(1-6):301-10.
1998: M Beaulieu; Eric Lévesque; Olivier Barbier; David Turgeon; Geoffroy Bélanger; Dean W Hum; Alain Bélanger
Isolation and characterization of a simian UDP-glucuronosyltransferase UGT2B18 active on 3-hydroxyandrogens.
Journal of molecular biology 1998;275(5):785-94.
1998: Eric Lévesque; M Beaulieu; Chantal Guillemette; Dean W Hum; Alain Bélanger
Effect of fibroblastic growth factors (FGF) on steroid UDP-glucuronosyltransferase expression and activity in the LNCaP cell line.
The Journal of steroid biochemistry and molecular biology 1998;64(1-2):43-8.
1998: Steeve Couillard; Mathieu Gutmann; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Comparison of the effects of the antiestrogens EM-800 and tamoxifen on the growth of human breast ZR-75-1 cancer xenografts in nude mice.
Cancer research 1998;58(1):60-4.
1997: MD Green; Geoffroy Bélanger; Dean W Hum; Alain Bélanger; Thomas R Tephly
Glucuronidation of opioids, carboxylic acid-containing drugs, and hydroxylated xenobiotics catalyzed by expressed monkey UDP-glucuronosyltransferase 2B9 protein.
Drug metabolism and disposition: the biological fate of chemicals 1997;25(12):1389-94.
1997: A Sourla; S Luo; Claude Labrie; Alain Bélanger; Fernand Labrie
Morphological changes induced by 6-month treatment of intact and ovariectomized mice with tamoxifen and the pure antiestrogen EM-800.
Endocrinology 1997;138(12):5605-17.
1997: S Luo; Céline Martel; Sylvain Gauthier; Yves Mérand; Alain Bélanger; Claude Labrie; Fernand Labrie
Long-term inhibitory effects of a novel anti-estrogen on the growth of ZR-75-1 and MCF-7 human breast cancer tumors in nude mice.
International journal of cancer. Journal international du cancer 1997;73(5):735-9.
1997: Geoffroy Bélanger; M Beaulieu; Eric Lévesque; Dean W Hum; Alain Bélanger
Expression and characterization of a novel UDP-glucuronosyltransferase, UGT2B9, from cynomolgus monkey.
DNA and cell biology 1997;16(10):1195-205.
1997: M Beaulieu; Eric Lévesque; André Tchernof; Barbara G Beatty; Alain Bélanger; Dean W Hum
Chromosomal localization, structure, and regulation of the UGT2B17 gene, encoding a C19 steroid metabolizing enzyme.
DNA and cell biology 1997;16(10):1143-54.
1997: Fernand Labrie; Pierre Diamond; Leonello Cusan; José Luis Gomez; Alain Bélanger; Bernard Candas
Effect of 12-month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women.
The Journal of clinical endocrinology and metabolism 1997;82(10):3498-505.
1997: S Luo; A Sourla; Claude Labrie; Alain Bélanger; Fernand Labrie
Combined effects of dehydroepiandrosterone and EM-800 on bone mass, serum lipids, and the development of dimethylbenz(A)anthracene-induced mammary carcinoma in the rat.
Endocrinology 1997;138(10):4435-44.
1997: Jacques Simard; Claude Labrie; Alain Bélanger; Sylvain Gauthier; SM Singh; Yves Mérand; Fernand Labrie
Characterization of the effects of the novel non-steroidal antiestrogen EM-800 on basal and estrogen-induced proliferation of T-47D, ZR-75-1 and MCF-7 human breast cancer cells in vitro.
International journal of cancer. Journal international du cancer 1997;73(1):104-12.
1997: Eric Lévesque; M Beaulieu; M D Green; Thomas R Tephly; Alain Bélanger; Dean W Hum
Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene.
Pharmacogenetics 1997;7(4):317-25.
1997: Fernand Labrie; Alain Bélanger; Leonello Cusan; Bernard Candas
Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology.
The Journal of clinical endocrinology and metabolism 1997;82(8):2403-9.
1997: Fernand Labrie; Alain Bélanger; Leonello Cusan; José Luis Gomez; Bernard Candas
Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging.
The Journal of clinical endocrinology and metabolism 1997;82(8):2396-402.
1997: S Luo; Claude Labrie; Alain Bélanger; Fernand Labrie
Effect of dehydroepiandrosterone on bone mass, serum lipids, and dimethylbenz(a)anthracene-induced mammary carcinoma in the rat.
Endocrinology 1997;138(8):3387-94.
1997: Sylvain Gauthier; B Caron; Julie Cloutier; Y L Dory; A Favre; D Larouche; J Mailhot; C Ouellet; A Schwerdtfeger; Gilles Leblanc; Céline Martel; Jacques Simard; Yves Mérand; Alain Bélanger; Claude Labrie; Fernand Labrie
(S)-(+)-4-[7-(2,2-dimethyl-1-oxopropoxy)-4-methyl-2-[4-[2-(1-piperidinyl)-ethoxy]phenyl]-2H-1-benzopyran-3-yl]-phenyl 2,2-dimethylpropanoate (EM-800): a highly potent, specific, and orally active nonsteroidal antiestrogen.
Journal of medicinal chemistry 1997;40(14):2117-22.
1997: Chantal Guillemette; Eric Lévesque; M Beaulieu; David Turgeon; Dean W Hum; Alain Bélanger
Differential regulation of two uridine diphospho-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells.
Endocrinology 1997;138(7):2998-3005.
1997: Fernand Labrie; Leonello Cusan; José Luis Gomez; P Diamond; RE Suburu; M Lemay; B Tetu; Y Fradet; Alain Bélanger; Bernard Candas
Neoadjuvant hormonal therapy: the Canadian experience.
Urology 1997;49(3A Suppl):56-64.
1997: B Lavallée; P R Provost; Z Kahwash; J E Nestler; Alain Bélanger
Effect of insulin on serum levels of dehydroepiandrosterone metabolites in men.
Clinical endocrinology 1997;46(1):93-100.
1997: Fernand Labrie; Van Luu-The; Sheng-Xiang Lin; Claude Labrie; Jacques Simard; Rock Breton; Alain Bélanger
The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology.
Steroids 1997;62(1):148-58.
1997: P R Provost; B Lavallée; Alain Bélanger
Transfer of dehydroepiandrosterone- and pregnenolone-fatty acid esters between human lipoproteins.
The Journal of clinical endocrinology and metabolism 1997;82(1):182-7.
1996: M Beaulieu; Eric Lévesque; Dean W Hum; Alain Bélanger
Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids.
The Journal of biological chemistry 1996;271(37):22855-62.
1996: B Lavallée; P R Provost; R Roy; M C Gauthier; Alain Bélanger
Dehydroepiandrosterone-fatty acid esters in human plasma: formation, transport and delivery to steroid target tissues.
The Journal of endocrinology 1996;150 Suppl():S119-24.
1996: Pierre Diamond; Leonello Cusan; José Luis Gomez; Alain Bélanger; Fernand Labrie
Metabolic effects of 12-month percutaneous dehydroepiandrosterone replacement therapy in postmenopausal women.
The Journal of endocrinology 1996;150 Suppl():S43-50.
1996: Chantal Guillemette; Dean W Hum; Alain Bélanger
Levels of plasma C19 steroids and 5 alpha-reduced C19 steroid glucuronides in primates, rodents, and domestic animals.
The American journal of physiology 1996;271(2 Pt 1):E348-53.
1996: Chantal Guillemette; Dean W Hum; Alain Bélanger
Regulation of steroid glucuronosyltransferase activities and transcripts by androgen in the human prostatic cancer LNCaP cell line.
Endocrinology 1996;137(7):2872-9.
1996: I Dufort; Yves Tremblay; Alain Bélanger; Fernand Labrie; Van Luu-The
Isolation and characterization of a stereospecific 3beta-hydroxysteriod sulfotransferase (pregnenolone sulfotransferase) cDNA.
DNA and cell biology 1996;15(6):481-7.
1996: Chantal Guillemette; Dean W Hum; Alain Bélanger
Evidence for a role of glucuronosyltransferase in the regulation of androgen action in the human prostatic cancer cell line LNCaP.
The Journal of steroid biochemistry and molecular biology 1996;57(3-4):225-31.
1995: Fernand Labrie; Alain Bélanger; Jacques Simard; Claude Labrie
DHEA and peripheral androgen and estrogen formation: intracinology.
Annals of the New York Academy of Sciences 1995;774():16-28.
1995: Chantal Guillemette; Dean W Hum; Alain Bélanger
Specificity of glucuronosyltransferase activity in the human cancer cell line LNCaP, evidence for the presence of at least two glucuronosyltransferase enzymes.
The Journal of steroid biochemistry and molecular biology 1995;55(3-4):355-62.
1995: Alain Bélanger; H van Halbeek; H C Graves; K Grandbois; Thomas A Stamey; L Huang; I Poppe; Fernand Labrie
Molecular mass and carbohydrate structure of prostate specific antigen: studies for establishment of an international PSA standard.
The Prostate 1995;27(4):187-97.
1995: Geoffroy Bélanger; M Beaulieu; B Marcotte; Eric Lévesque; Chantal Guillemette; Dean W Hum; Alain Bélanger
Expression of transcripts encoding steroid UDP-glucuronosyltransferases in human prostate hyperplastic tissue and the LNCaP cell line.
Molecular and cellular endocrinology 1995;113(2):165-73.
1995: Marie-Hélène Vallée; S Perron; Yves Tremblay; Alain Bélanger
Regulation of guinea pig adrenal P450c21 messenger RNA, protein and activity by RU486.
The Journal of steroid biochemistry and molecular biology 1995;54(1-2):31-8.
1995: P R Provost; Yves Tremblay; Moustapha El-Amine; Alain Bélanger
Guinea pig apolipoprotein D RNA diversity, and developmental and gestational modulation of mRNA levels.
Molecular and cellular endocrinology 1995;109(2):225-36.
1995: Chantal Guillemette; Alain Bélanger
Glucuronosyltransferase activity in human cancer cell line LNCaP.
Molecular and cellular endocrinology 1995;107(2):131-9.
1995: Yves Tremblay; Alain Bélanger; A Fleury; Claude Beaudoin; P Provost; Isabelle Martineau
Studies of the guinea pig adrenal cytochrome P450c17 cDNA.
Endocrine research 1995;21(1-2):495-507.
1995: Alain Bélanger; Yves Tremblay; Marie-Hélène Vallée; P H Provencher; S Perron
Regulation of 21-hydroxylase activity by steroids.
Endocrine research 1995;21(1-2):329-41.
1994: Yves Tremblay; A Fleury; Claude Beaudoin; Marie-Hélène Vallée; Alain Bélanger
Molecular cloning and expression of guinea pig cytochrome P450c17 cDNA (steroid 17 alpha-hydroxylase/17,20 lyase): tissue distribution, regulation, and substrate specificity of the expressed enzyme.
DNA and cell biology 1994;13(12):1199-212.
1994: Alain Bélanger; Bernard Candas; A Dupont; Leonello Cusan; Pierre Diamond; José Luis Gomez; Fernand Labrie
Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80-year-old men.
The Journal of clinical endocrinology and metabolism 1994;79(4):1086-90.
1994: R Sanchez; Y de Launoit; Francine Durocher; Alain Bélanger; Fernand Labrie; Jacques Simard
Formation and degradation of dihydrotestosterone by recombinant members of the rat 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase family.
Molecular and cellular endocrinology 1994;103(1-2):29-38.
1994: S Perron; Alain Bélanger
Effects of 4-MA, a potent inhibitor of 5 alpha-reductase, on 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase activity in guinea pig adrenals.
Steroids 1994;59(6):371-6.
1994: S Li; Céline Martel; S Dauvois; Alain Bélanger; Fernand Labrie
Effect of estrone on the growth of 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in the rat: a model of postmenopausal breast cancer.
Endocrinology 1994;134(3):1352-7.
1993: Fernand Labrie; Alain Bélanger; A Dupont; Van Luu-The; J Simard; C Labrie
Science behind total androgen blockade: from gene to combination therapy.
Clinical and investigative medicine. Médecine clinique et experimentale 1993;16(6):475-92.
1993: Alain Bélanger; P M Rong; S Liu; L Lavoie; Fernand Labrie
Characterization and measurement of prostate-specific antigen using monoclonal antibodies.
Clinical and investigative medicine. Médecine clinique et experimentale 1993;16(6):409-14.
1993: R Roy; Alain Bélanger
ZR-75-1 breast cancer cells generate nonconjugated steroids from low density lipoprotein-incorporated lipoidal dehydroepiandrosterone.
Endocrinology 1993;133(2):683-9.
1993: Céline Martel; C Trudel; J Couet; Claude Labrie; Alain Bélanger; Fernand Labrie
Blockade of androstenedione-induced stimulation of androgen-sensitive parameters in the rat prostate by combination of Flutamide and 4-MA.
Molecular and cellular endocrinology 1993;91(1-2):43-9.
1993: B Bélanger; J Fiet; Alain Bélanger
Effects of adrenocorticotropin on adrenal and plasma 11 beta-hydroxyandrostenedione in the guinea pig and determination of its relative androgen potency.
Steroids 1993;58(1):29-34.
1993: Fernand Labrie; A Dupont; Jacques Simard; Van Luu-The; Alain Bélanger
Intracrinology: the basis for the rational design of endocrine therapy at all stages of prostate cancer.
European urology 1993;24 Suppl 2():94-105.
1993: Fernand Labrie; Shi-Hua Li; Alain Bélanger; J Côté; Yves Mérand; M Lepage
Controlled release low dose medroxyprogesterone acetate (MPA) inhibits the development of mammary tumors induced by dimethyl-benz(a) anthracene in the rat.
Breast cancer research and treatment 1993;26(3):253-65.
1992: G Pelletier; E Dupont; Jacques Simard; Van Luu-The; Alain Bélanger; Fernand Labrie
Ontogeny and subcellular localization of 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) in the human and rat adrenal, ovary and testis.
The Journal of steroid biochemistry and molecular biology 1992;43(5):451-67.
1992: R Roy; Alain Bélanger
Elevated levels of endogenous pregnenolone fatty acid esters in follicular fluid high density lipoproteins support progesterone synthesis in porcine granulosa cells.
Endocrinology 1992;131(3):1390-6.
1992: B Bélanger; R Roy; Alain Bélanger
Administration of pregnenolone and dehydroepiandrosterone to guinea pigs and rats causes the accumulation of fatty acid esters of pregnenolone and dehydroepiandrosterone in plasma lipoproteins.
Steroids 1992;57(9):430-6.
1992: P H Provencher; Yves Tremblay; B Bélanger; Alain Bélanger
Studies of adrenal steroidogenic enzymes in guinea pigs.
The American journal of physiology 1992;262(6 Pt 1):E869-74.
1992: P H Provencher; R Roy; Alain Bélanger
Pregnenolone fatty acid esters incorporated into lipoproteins: substrates in adrenal steroidogenesis.
Endocrinology 1992;130(5):2717-24.
1992: Y de Launoit; H F Zhao; Alain Bélanger; Fernand Labrie; Jacques Simard
Expression of liver-specific member of the 3 beta-hydroxysteroid dehydrogenase family, an isoform possessing an almost exclusive 3-ketosteroid reductase activity.
The Journal of biological chemistry 1992;267(7):4513-7.
1992: Fernand Labrie; Jacques Simard; Van Luu-The; Georges Pelletier; Alain Bélanger; Y Lachance; H F Zhao; Claude Labrie; N Breton; Y de Launoit
Structure and tissue-specific expression of 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues.
The Journal of steroid biochemistry and molecular biology 1992;41(3-8):421-35.
1992: B Bélanger; S Caron; P Boudou; J Fiet; Alain Bélanger
Adrenal steroidogenesis in the guinea pig: effects of androgens.
Steroids 1992;57(2):76-81.
1992: P H Provencher; Yves Tremblay; Alain Bélanger
Effects of C19 steroids on adrenal steroidogenic enzyme activities and their mRNA levels in guinea-pig fasciculata-glomerulosa cells in primary culture.
The Journal of endocrinology 1992;132(2):269-76.
1991: R Roy; Alain Bélanger
Lipoprotein-incorporated pregnenolone fatty acid esters act as substrate for ovarian progestin synthesis.
Biochemical and biophysical research communications 1991;179(3):1576-81.
1991: P H Provencher; Alain Bélanger; J Fiet
Effects of RU 486 on adrenal steroidogenesis in the guinea-pig.
The Journal of endocrinology 1991;130(1):71-8.
1991: Alain Bélanger; M Brochu; D Lacoste; C Noël; Fernand Labrie; A Dupont; Leonello Cusan; S Caron; J Couture
Steroid glucuronides: human circulatory levels and formation by LNCaP cells.
The Journal of steroid biochemistry and molecular biology 1991;40(4-6):593-8.
1990: B Bélanger; S Caron; Alain Bélanger; A Dupont
Steroid fatty acid esters in adrenals and plasma: effects of ACTH.
The Journal of endocrinology 1990;127(3):505-11.
1990: Fernand Labrie; A Dupont; Alain Bélanger; Y Lacourcière; L Béland; Leonello Cusan; R Lachance
Complete response to combination therapy with an LHRH agonist and flutamide in metastatic male breast cancer: a case report.
Clinical and investigative medicine. Médecine clinique et experimentale 1990;13(5):275-8.
1990: L Cusan; A Dupont; Alain Bélanger; R R Tremblay; G Manhes; Fernand Labrie
Treatment of hirsutism with the pure antiandrogen flutamide.
Journal of the American Academy of Dermatology 1990;23(3 Pt 1):462-9.
1990: B Bélanger; J Couture; S Caron; P Bodou; J Fiet; Alain Bélanger
Production and secretion of C-19 steroids by rat and guinea pig adrenals.
Steroids 1990;55(8):360-5.
1990: R Poulin; Donald Poirier; C Thériault; J Couture; Alain Bélanger; Fernand Labrie
Wide spectrum of steroids serving as substrates for the formation of lipoidal derivatives in ZR-75-1 human breast cancer cells.
Journal of steroid biochemistry 1990;35(2):237-47.
1990: Alain Bélanger; J Couture; S Caron; R Roy
Determination of nonconjugated and conjugated steroid levels in plasma and prostate after separation on C-18 columns.
Annals of the New York Academy of Sciences 1990;595():251-9.
1990: Alain Bélanger; Fernand Labrie; A Angeli
Unconjugated and glucuronide steroid levels in human breast cyst fluid.
Annals of the New York Academy of Sciences 1990;586():93-100.
1989: D Lacoste; D Dubé; Alain Bélanger; Fernand Labrie
Effect of 2-week combination therapy with the luteinizing hormone-releasing hormone (LHRH) agonist [D-Trp6, des-Gly-NH2(10)]LHRH ethylamide and the antiandrogen flutamide on prostate structure and steroid levels in the dog.
Molecular and cellular endocrinology 1989;67(2-3):131-8.
1989: D Lacoste; D Dubé; C Trudel; Alain Bélanger; Fernand Labrie
Normal gonadal functions and fertility after 23 months of treatment of prepubertal male and female dogs with the GnRh agonist [D-Trp6, des-Gly-NH2(10)]GnRH ethylamide.
Journal of andrology 1989;10(6):456-65.
1989: D Lacoste; Fernand Labrie; D Dubé; Alain Bélanger; T Tice; R M Gilley; K L Pledger
Reversible inhibition of testicular androgen secretion by 3-, 5- and 6-month controlled-release microsphere formulations of the LH-RH agonist [D-Trp6, des-Gly-NH10(2)] LH-RH ethylamide in the dog.
Journal of steroid biochemistry 1989;33(5):1007-11.
1989: Fernand Labrie; A Dupont; Leonello Cusan; G Manhès; N Bergeron; Y Lacourcière; S Pineault; Alain Bélanger; G Monfette; J Emond
Combination therapy with castration and flutamide: today's treatment of choice for prostate cancer.
Journal of steroid biochemistry 1989;33(4B):817-21.
1989: R Roy; Alain Bélanger
Presence of fatty acid esters of pregnenolone in follicular fluid from women undergoing follicle stimulation.
Steroids 1989;54(4):385-400.
1989: R Roy; Alain Bélanger
Formation of lipoidal steroids in follicular fluid.
Journal of steroid biochemistry 1989;33(2):257-62.
1989: D Lacoste; S Caron; Alain Bélanger; Fernand Labrie
Effect of 3-week treatment with [D-Trp6, des-Gly-NH10(2)]LHRH ethylamide, aminoglutethimide, ketoconazole or flutamide alone or in combination on testicular, serum, adrenal and prostatic steroid levels in the dog.
Journal of steroid biochemistry 1989;33(2):233-42.
1989: Richard Poulin; Donald Poirier; Y Merand; C Thériault; Alain Bélanger; Fernand Labrie
Extensive esterification of adrenal C19-delta 5-sex steroids to long-chain fatty acids in the ZR-75-1 human breast cancer cell line.
The Journal of biological chemistry 1989;264(16):9335-43.
1989: Fernand Labrie; A Dupont; Alain Bélanger; Leonello Cusan; M Brochu; E Turina; S Pinault; Y Lacourciere; J Emond
Anti-hormone treatment for prostate cancer relapsing after treatment with flutamide and castration. Addition of aminoglutethimide and low dose hydrocortisone to combination therapy.
British journal of urology 1989;63(6):634-8.
1989: Alain Bélanger; A Locong; C Noel; Leonello Cusan; A Dupont; J Prévost; S Caron; J Sévigny
Influence of diet on plasma steroids and sex hormone-binding globulin levels in adult men.
Journal of steroid biochemistry 1989;32(6):829-33.
1989: B Bélanger; Alain Bélanger; Fernand Labrie; A Dupont; Leonello Cusan; G Monfette
Comparison of residual C-19 steroids in plasma and prostatic tissue of human, rat and guinea pig after castration: unique importance of extratesticular androgens in men.
Journal of steroid biochemistry 1989;32(5):695-8.
1989: Fernand Labrie; A Dupont; Leonello Cusan; G Manhès; N Bergeron; Y Lacourcière; S Pineault; Alain Bélanger; G Monfette; J Emond
Combination therapy with flutamide and castration: its benefits at various stages of prostate cancer.
Progress in clinical and biological research 1989;303():161-7.
1989: R Roy; Alain Bélanger
Lipoproteins: carriers of dehydroepiandrosterone fatty acid esters in human serum.
Journal of steroid biochemistry 1989;34(1-6):559-61.
1988: P G Spinola; Bianca Marchetti; Yves Mérand; Alain Bélanger; Fernand Labrie
Effects of the aromatase inhibitor 4-hydroxyandrostenedione and the antiandrogen flutamide on growth and steroid levels in DMBA-induced rat mammary tumors.
Breast cancer research and treatment 1988;12(3):287-96.
1988: Alain Bélanger; Fernand Labrie; A Dupont; M Brochu; Leonello Cusan
Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma.
Clinical and investigative medicine. Médecine clinique et experimentale 1988;11(5):321-6.
1988: J Prévost; Alain Bélanger
Formation of estrogen glucuronides by human granulosa-luteal cells isolated from human menopausal gonadotropin-stimulated cycles for in vitro fertilization.
Biology of reproduction 1988;38(5):975-9.
1988: D Lacoste; R St-Arnaud; Alain Bélanger; Fernand Labrie
A pure antiandrogen does not interfere with the LHRH agonist-induced blockade of testicular androgen secretion in the dog.
Molecular and cellular endocrinology 1988;56(1-2):141-7.
1988: Sital Moorjani; A Dupont; Fernand Labrie; Paul J Lupien; Claude Gagné; D Brun; M Giguère; Alain Bélanger; Leonello Cusan
Changes in plasma lipoproteins during various androgen suppression therapies in men with prostatic carcinoma: effects of orchiectomy, estrogen, and combination treatment with luteinizing hormone-releasing hormone agonist and flutamide.
The Journal of clinical endocrinology and metabolism 1988;66(2):314-22.
1988: Fernand Labrie; A Dupont; Leonello Cusan; Alain Bélanger; M Giguère; Claude Labrie; Y Lacourcière; G Monfette; J Emond
Combination therapy with flutamide and [D-Trp6, des-Gly-NH2(10)]LHRH ethylamide in stage C and D prostate cancer: today's therapy of choice--rationale and 5-year clinical experience.
Progress in clinical and biological research 1988;262():11-63.
1988: Fernand Labrie; A Dupont; M Giguère; J P Borsanyi; Y Lacourciere; Alain Bélanger; R Lachance; J Emond; G Monfette
Combination therapy with flutamide and castration (orchiectomy or LHRH agonist): the minimal endocrine therapy in both untreated and previously treated patients with advanced prostate cancer.
Progress in clinical and biological research 1988;260():41-62.
1988: Alain Bélanger; M Giasson; J Couture; A Dupont; Leonello Cusan; F Labrie
Plasma levels of hydroxy-flutamide in patients with prostatic cancer receiving the combined hormonal therapy: an LHRH agonist and flutamide.
The Prostate 1988;12(1):79-84.
1987: J Prévost; M Brochu; Alain Bélanger; R Lambert
Conjugated and unconjugated C-21, C-19 and C-18 steroid concentrations in human follicular fluid from hyperstimulated follicles.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 1987;1(4):331-8.
1987: M Brochu; Alain Bélanger; A Dupont; Leonello Cusan; Fernand Labrie
Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate.
Journal of steroid biochemistry 1987;28(6):619-22.
1987: M Brochu; Alain Bélanger; R R Tremblay
Plasma levels of C-19 steroids and 5 alpha-reduced steroid glucuronides in hyperandrogenic and idiopathic hirsute women.
Fertility and sterility 1987;48(6):948-53.
1987: I Luthy; S Caron; Alain Bélanger; F Labrie
Effects of flutamide, a pure antiandrogen, on endocrine parameters, in the adult female rat.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 1987;1(2):151-68.
1987: Sital Moorjani; A Dupont; Fernand Labrie; Paul J Lupien; D Brun; Claude Gagné; M Giguère; Alain Bélanger
Increase in plasma high-density lipoprotein concentration following complete androgen blockage in men with prostatic carcinoma.
Metabolism: clinical and experimental 1987;36(3):244-50.
1987: Fernand Labrie; A Dupont; Alain Bélanger; Leonello Cusan; M Giguère; Y Lacourcière; I Luthy; D Bégin; Claude Labrie; J Simard
Combination therapy in stage C and D prostatic cancer: rationale and five year clinical experience.
Cancer metastasis reviews 1987;6(4):615-36.
1987: M Brochu; Alain Bélanger
Comparative study of plasma steroid and steroid glucuronide levels in normal men and in men with benign prostatic hyperplasia.
The Prostate 1987;11(1):33-40.
1986: Fernand Labrie; A Dupont; Alain Bélanger; R St-Arnaud; M Giguère; Y Lacourcière; J Emond; G Monfette
Treatment of prostate cancer with gonadotropin-releasing hormone agonists.
Endocrine reviews 1986;7(1):67-74.
1986: Fernand Labrie; A Dupont; Alain Bélanger; Y Lacourcière; J E Monfette; G Monfette
[Combined anti-androgen treatment in adenocarcinoma of the prostate: first use of a new therapeutically efficacious principle in hormone-dependent cancer].
Annales d'urologie 1986;20(2):98-106.
1984: F Labrie; A Dupont; Alain Bélanger; J Emond; G Monfette
Simultaneous administration of pure antiandrogens, a combination necessary for the use of luteinizing hormone-releasing hormone agonists in the treatment of prostate cancer.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(12):3861-3.
1982: N Faure; F Labrie; André Lemay; Alain Bélanger; Y Gourdeau; B Laroche; G Robert
Inhibition of serum androgen levels by chronic intranasal and subcutaneous administration of a potent luteinizing hormone-releasing hormone (LH-RH) agonist in adult men.
Fertility and sterility 1982;37(3):416-24.
1982: F A Lefebvre; C Séguin; Alain Bélanger; S Caron; M R Sairam; J P Raynaud; F Labrie
Combined long-term treatment with an LHRH agonist and a pure antiandrogen blocks androgenic influence in the rat.
The Prostate 1982;3(6):569-78.
1982: F Labrie; C Séguin; F A Lefebvre; J Massicotte; G Pelletier; J P Borgus; P A Kelly; J J Reeves; Alain Bélanger
Intraovarian actions of GnRH.
Advances in experimental medicine and biology 1982;147():211-22.
1981: F Labrie; C Séguin; Alain Bélanger; F A Lefebvre; J Massicotte; P A Kelly; G Pelletier; J J Reeves; André Lemay; Leonello Cusan; J P Raynaud
Contraception with LHRH agonists, a new physiological approach.
Reproducción 1981;5(4):229-41.
1981: C Séguin; Alain Bélanger; Leonello Cusan; G Pelletier; J J Reeves; F A Lefebvre; P A Kelly; F Labrie
Relative importance of the adenohypophyseal and gonadal sites in inhibitory action of LHRH agonists.
Biology of reproduction 1981;24(4):889-901.
1981: Alain Bélanger; Leonello Cusan; S Caron; N Barden; A Dupont
Ovarian progestins, androgens and estrogen throughout the 4-day estrous cycle in the rat.
Biology of reproduction 1981;24(3):591-6.
1981: F Labrie; Alain Bélanger; P A Kelly; C Séguin; Leonello Cusan; F A Lefebvre; J J Reeves; André Lemay; N Faure; Y Gourdeau; J P Raynaud
Antifertility effects of luteinizing hormone-releasing hormone (LHRH) agonists.
Progress in clinical and biological research 1981;74():273-91.
1980: R Carmichael; Alain Bélanger; Leonello Cusan; C Séguin; S Caron; F Labrie
Increased testicular 5 alpha-androstane-3 alpha, 17 beta-diol formation induced by treatment with [D-Ser (TBU) 6, des-Gly-NH2(10)] LHRH ethylamide in the rat.
Steroids 1980;36(4):383-91.
1980: Alain Bélanger; Leonello Cusan; C Auclair; C Séguin; S Caron; F Labrie
Effect of an LHRH agonist and hCG on testicular steroidogenesis in the adult rat.
Biology of reproduction 1980;22(5):1094-101.