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Najib Naamane

Research Profile

Anatomy

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Oligonucleotide Array Sequence Analysis

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Physiology

Chemicals & Drugs

Disorders

Type 1 Diabetes Mellitus

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Publications

TOP 3
Daniel A Cunha; Décio L Eizirik; Makiko Fukaya; Carla M Germano; Esteban N Gurzov; Conny Gysemans; Heather P Harding; Mariana Igoillo-Esteve; Piero Marchetti; Ihsane Marhfour; Lorella Marselli; Chantal Mathieu; Najib Naamane; David Ron; Jean-Marie Vanderwinden; Miriam Cnop
Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
Esteban N Gurzov; Conny Gysemans; Mariana Igoillo-Esteve; S Kitajima; P Marchetti; I Marhfour; Chantal Mathieu; Najib Naamane; Fernanda Ortis; Erwin F Wagner; Torben F Orntoft; Latifa Bakiri; J Barthson; Decio L Eizirik
Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation.
Michael Volkmar; Ute Volkmar; Mariana Igoillo-Esteve; Piero Marchetti; Matilde Masini; Najib Naamane; Matladi N Ndlovu; Marco Bugliani; Emilie Calonne; Miriam Cnop; Daniel A Cunha; Sarah Dedeurwaerder; Matthieu Defrance; Silvia Del Guerra; Rachel Deplus; Decio L Eizirik; François Fuks
DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.

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All Publications

2012: Daniel A Cunha; Décio L Eizirik; Makiko Fukaya; Carla M Germano; Esteban N Gurzov; Conny Gysemans; Heather P Harding; Mariana Igoillo-Esteve; Piero Marchetti; Ihsane Marhfour; Lorella Marselli; Chantal Mathieu; Najib Naamane; David Ron; Jean-Marie Vanderwinden; Miriam Cnop
Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
Diabetes 2012;61(11):2763-75.
2012: Esteban N Gurzov; Conny Gysemans; Mariana Igoillo-Esteve; S Kitajima; P Marchetti; I Marhfour; Chantal Mathieu; Najib Naamane; Fernanda Ortis; Erwin F Wagner; Torben F Orntoft; Latifa Bakiri; J Barthson; Decio L Eizirik
Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation.
Oncogene 2012;31(13):1723-32.
2012: Michael Volkmar; Ute Volkmar; Mariana Igoillo-Esteve; Piero Marchetti; Matilde Masini; Najib Naamane; Matladi N Ndlovu; Marco Bugliani; Emilie Calonne; Miriam Cnop; Daniel A Cunha; Sarah Dedeurwaerder; Matthieu Defrance; Silvia Del Guerra; Rachel Deplus; Decio L Eizirik; François Fuks
DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.
The EMBO journal 2012;31(6):1405-26.
2011: Fabrice Moore; Najib Naamane; Maikel L Colli; Thomas Bouckenooghe; Fernanda Ortis; Esteban N Gurzov; Mariana Igoillo-Esteve; Chantal Mathieu; Gianluca Bontempi; Thomas Thykjaer; Torben F Ørntoft; Decio L Eizirik
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.
The Journal of biological chemistry 2011;286(2):929-41.
2010: Fernanda Ortis; Najib Naamane; Daisy Flamez; Laurence Ladrière; Fabrice Moore; Daniel Cunha; Maikel L Colli; Thomas Thykjaer; Kasper Thorsen; Torben F Orntoft; Decio L Eizirik
Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells.
Diabetes 2010;59(2):358-74.
2010: Robin Liechti; Gábor Csárdi; Sven Bergmann; Frédéric Schütz; Thierry Sengstag; Sylvia F Boj; Joan-Marc Servitja; Jorge Ferrer; Leentje Van Lommel; Frans Schuit; Sonia Klinger; Bernard Thorens; Najib Naamane; Decio L Eizirik; Lorella Marselli; Marco Bugliani; Piero Marchetti; Stephanie Lucas; Cecilia Holm; C Victor Jongeneel; Ioannis Xenarios
EuroDia: a beta-cell gene expression resource.
Database : the journal of biological databases and curation 2010;2010():baq024.
2008: Fernanda Ortis; Pierre Pirot; Najib Naamane; A Y Kreins; Joanne Rasschaert; Fabrice Moore; E Théâtre; C Verhaeghe; Nils E Magnusson; Alain Chariot; Torben F Orntoft; Decio L Eizirik
Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells.
Diabetologia 2008;51(7):1213-25.
2007: Pierre Pirot; Najib Naamane; F Libert; Nils E Magnusson; Torben F Ørntoft; Alessandra K Cardozo; Decio L Eizirik
Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs.
Diabetologia 2007;50(5):1006-14.
2007: Najib Naamane; Jacques van Helden; Decio L Eizirik
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells.
BMC bioinformatics 2007;8():55.
2004: Burak Kutlu; Najib Naamane; Laurence Berthou; Decio L Eizirik
New approaches for in silico identification of cytokine-modified beta cell gene networks.
Annals of the New York Academy of Sciences 2004;1037():41-58.