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Paul Naccache

Research Profile

Anatomy

Neutrophils

Chemicals & Drugs

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Phosphorylation

Physiology

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Louis Marois; Myriam Vaillancourt; Guillaume Paré; Valérie Gagné; Maria J G Fernandes; Emmanuelle Rollet-Labelle; Paul H Naccache
CIN85 modulates the down-regulation of Fc gammaRIIa expression and function by c-Cbl in a PKC-dependent manner in human neutrophils.
Louis Marois; Guillaume Paré; Myriam Vaillancourt; Emmanuelle Rollet-Labelle; Paul H Naccache
Fc gammaRIIIb triggers raft-dependent calcium influx in IgG-mediated responses in human neutrophils.
Mireille St-Onge; Stéphanie Lagarde; Cynthia Laflamme; Emmanuelle Rollet-Labelle; Louis Marois; Paul H Naccache; Marc Pouliot
Proteinase-activated receptor-2 up-regulation by Fcgamma-receptor activation in human neutrophils.

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All Publications

2011: Louis Marois; Myriam Vaillancourt; Guillaume Paré; Valérie Gagné; Maria J G Fernandes; Emmanuelle Rollet-Labelle; Paul H Naccache
CIN85 modulates the down-regulation of Fc gammaRIIa expression and function by c-Cbl in a PKC-dependent manner in human neutrophils.
The Journal of biological chemistry 2011;286(17):15073-84.
2011: Louis Marois; Guillaume Paré; Myriam Vaillancourt; Emmanuelle Rollet-Labelle; Paul H Naccache
Fc gammaRIIIb triggers raft-dependent calcium influx in IgG-mediated responses in human neutrophils.
The Journal of biological chemistry 2011;286(5):3509-19.
2010: Mireille St-Onge; Stéphanie Lagarde; Cynthia Laflamme; Emmanuelle Rollet-Labelle; Louis Marois; Paul H Naccache; Marc Pouliot
Proteinase-activated receptor-2 up-regulation by Fcgamma-receptor activation in human neutrophils.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(6):2116-25.
2010: Oana Popa-Nita; Paul H Naccache
Crystal-induced neutrophil activation.
Immunology and cell biology 2010;88(1):32-40.
2009: Oana Popa-Nita; Sophie Proulx; Guillaume Paré; Emmanuelle Rollet-Labelle; Paul H Naccache
Crystal-induced neutrophil activation: XI. Implication and novel roles of classical protein kinase C.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(3):2104-14.
2009: Louis Marois; Myriam Vaillancourt; Sébastien Marois; Sophie Proulx; Guillaume Paré; Emmanuelle Rollet-Labelle; Paul H Naccache
The ubiquitin ligase c-Cbl down-regulates FcgammaRIIa activation in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2374-84.
2008: Oana Popa-Nita; Louis Marois; Guillaume Paré; Paul H Naccache
Crystal-induced neutrophil activation: X. Proinflammatory role of the tyrosine kinase Tec.
Arthritis and rheumatism 2008;58(6):1866-76.
2007: Chantal Burelout; Nathalie Thibault; Danielle Harbour; Paul H Naccache; Sylvain G Bourgoin
The PGE2-induced inhibition of the PLD activation pathway stimulated by fMLP in human neutrophils is mediated by PKA at the PI3-Kgamma level.
Biochemical pharmacology 2007;74(5):730-41.
2007: Oana Popa-Nita; Emmanuelle Rollet-Labelle; Nathalie Thibault; Caroline Gilbert; Sylvain G Bourgoin; Paul H Naccache
Crystal-induced neutrophil activation. IX. Syk-dependent activation of class Ia phosphatidylinositol 3-kinase.
Journal of leukocyte biology 2007;82(3):763-73.
2007: Chantal Burelout; Paul H Naccache; Sylvain G Bourgoin
Dissociation between the translocation and the activation of Akt in fMLP-stimulated human neutrophils--effect of prostaglandin E2.
Journal of leukocyte biology 2007;81(6):1523-34.
2006: Myriam Vaillancourt; Sylvain Levasseur; Marie-Lisane Tremblay; Louis Marois; Emmanuelle Rollet-Labelle; Paul H Naccache
The Src homology 2-containing inositol 5-phosphatase 1 (SHIP1) is involved in CD32a signaling in human neutrophils.
Cellular signalling 2006;18(11):2022-32.
2006: Isaline Boulven; Sylvain Levasseur; Sébastien Marois; Guillaume Paré; Emmanuelle Rollet-Labelle; Paul H Naccache
Class IA phosphatidylinositide 3-kinases, rather than p110 gamma, regulate formyl-methionyl-leucyl-phenylalanine-stimulated chemotaxis and superoxide production in differentiated neutrophil-like PLB-985 cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7621-7.
2006: Philippe Desaulniers; Sébastien Marois; Guillaume Paré; Oana Popa-Nita; Caroline Gilbert; Paul H Naccache
Characterization of an activation factor released from human neutrophils after stimulation by triclinic monosodium urate crystals.
The Journal of rheumatology 2006;33(5):928-38.
2006: Maria J G Fernandes; Emmanuelle Rollet-Labelle; Guillaume Paré; Sébastien Marois; Marie-Lisane Tremblay; Jean-Luc Teillaud; Paul H Naccache
CD16b associates with high-density, detergent-resistant membranes in human neutrophils.
The Biochemical journal 2006;393(Pt 1):351-9.
2005: Maria J G Fernandes; Geneviève Lachance; Guillaume Paré; Emmanuelle Rollet-Labelle; Paul H Naccache
Signaling through CD16b in human neutrophils involves the Tec family of tyrosine kinases.
Journal of leukocyte biology 2005;78(2):524-32.
2004: Maritza Jaramillo; Marianne Godbout; Paul H Naccache; Martin Olivier
Signaling events involved in macrophage chemokine expression in response to monosodium urate crystals.
The Journal of biological chemistry 2004;279(50):52797-805.
2004: Chantal Burelout; Nathalie Thibault; Sylvain Levasseur; Sébastien Simard; Paul H Naccache; Sylvain G Bourgoin
Prostaglandin E2 inhibits the phospholipase D pathway stimulated by formyl-methionyl-leucyl-phenylalanine in human neutrophils. Involvement of EP2 receptors and phosphatidylinositol 3-kinase gamma.
Molecular pharmacology 2004;66(2):293-301.
2004: Emmanuelle Rollet-Labelle; Sébastien Marois; Kathy Barbeau; Stephen E Malawista; Paul H Naccache
Recruitment of the cross-linked opsonic receptor CD32A (FcgammaRIIA) to high-density detergent-resistant membrane domains in human neutrophils.
The Biochemical journal 2004;381(Pt 3):919-28.
2004: Maritza Jaramillo; Paul H Naccache; Martin Olivier
Monosodium urate crystals synergize with IFN-gamma to generate macrophage nitric oxide: involvement of extracellular signal-regulated kinase 1/2 and NF-kappa B.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5734-42.
2003: Caroline Gilbert; Sylvain Levasseur; Philippe Desaulniers; Andrée-Anne Dusseault; Nathalie Thibault; Sylvain G Bourgoin; Paul H Naccache
Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. II. Effects of LFM-A13, a specific Btk inhibitor.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):5235-43.
2003: Caroline Gilbert; Patrice E Poubelle; Pierre Borgeat; Marc Pouliot; Paul H Naccache
Crystal-induced neutrophil activation: VIII. Immediate production of prostaglandin E2 mediated by constitutive cyclooxygenase 2 in human neutrophils stimulated by urate crystals.
Arthritis and rheumatism 2003;48(4):1137-48.
2003: Sonya Grenier; Nicolas Flamand; Julie Pelletier; Paul H Naccache; Pierre Borgeat; Sylvain G Bourgoin
Arachidonic acid activates phospholipase D in human neutrophils; essential role of endogenous leukotriene B4 and inhibition by adenosine A2A receptor engagement.
Journal of leukocyte biology 2003;73(4):530-9.
2002: Caroline Gilbert; Emmanuelle Rollet-Labelle; Adriana C Caon; Paul H Naccache
Immunoblotting and sequential lysis protocols for the analysis of tyrosine phosphorylation-dependent signaling.
Journal of immunological methods 2002;271(1-2):185-201.
2002: Marc Pouliot; Marie-Elaine Fiset; Mireille Massé; Paul H Naccache; Pierre Borgeat
Adenosine up-regulates cyclooxygenase-2 in human granulocytes: impact on the balance of eicosanoid generation.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):5279-86.
2002: Line Bouchard; Paul H Naccache; Patrice E Poubelle
Promotion of neutrophil adherence to human osteoblasts by microcrystals and f-Met-Leu-Phe.
Biochemical and biophysical research communications 2002;296(3):759-64.
2002: Geneviève Lachance; Sylvain Levasseur; Paul H Naccache
Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. Implication of phosphatidynositol 3-kinases.
The Journal of biological chemistry 2002;277(24):21537-41.
2002: Line Bouchard; Rinaldo de Médicis; André Lussier; Paul H Naccache; Patrice E Poubelle
Inflammatory microcrystals alter the functional phenotype of human osteoblast-like cells in vitro: synergism with IL-1 to overexpress cyclooxygenase-2.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):5310-7.
2002: Frédéric Barabé; Guillaume Paré; Maria J G Fernandes; Sylvain G Bourgoin; Paul H Naccache
Cholesterol-modulating agents selectively inhibit calcium influx induced by chemoattractants in human neutrophils.
The Journal of biological chemistry 2002;277(16):13473-8.
2002: Frédéric Barabé; Emmanuelle Rollet-Labelle; Caroline Gilbert; Maria J G Fernandes; Samia N Naccache; Paul H Naccache
Early events in the activation of Fc gamma RIIA in human neutrophils: stimulated insolubilization, translocation to detergent-resistant domains, and degradation of Fc gamma RIIA.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4042-9.
2002: Caroline Gilbert; Emmanuelle Rollet-Labelle; Paul H Naccache
Preservation of the pattern of tyrosine phosphorylation in human neutrophil lysates. II. A sequential lysis protocol for the analysis of tyrosine phosphorylation-dependent signalling.
Journal of immunological methods 2002;261(1-2):85-101.
2002: Nathalie Thibault; Chantal Burelout; Danielle Harbour; Pierre Borgeat; Paul H Naccache; Sylvain G Bourgoin
Occupancy of adenosine A2a receptors promotes fMLP-induced cyclic AMP accumulation in human neutrophils: impact on phospholipase D activity and recruitment of small GTPases to membranes.
Journal of leukocyte biology 2002;71(2):367-77.
2001: Philippe Desaulniers; M Fernandes; Caroline Gilbert; Sylvain G Bourgoin; Paul H Naccache
Crystal-induced neutrophil activation. VII. Involvement of Syk in the responses to monosodium urate crystals.
Journal of leukocyte biology 2001;70(4):659-68.
2001: Caroline Gilbert; Frédéric Barabé; Emmanuelle Rollet-Labelle; Sylvain G Bourgoin; Shaun R McColl; B B Damaj; Paul H Naccache
Evidence for a role for SAM68 in the responses of human neutrophils to ligation of CD32 and to monosodium urate crystals.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(7):4664-71.
2001: V Garceau; Martin G Houle; F Chouinard; S Gagnon; Danielle Harbour; Paul H Naccache; Sylvain G Bourgoin
Characterization of cytohesin-1 monoclonal antibodies: expression in neutrophils and during granulocytic maturation of HL-60 cells.
Journal of immunological methods 2001;249(1-2):121-36.
2000: Paul H Naccache; Sylvain Levasseur; Geneviève Lachance; S Chakravarti; Sylvain G Bourgoin; Shaun R McColl
Stimulation of human neutrophils by chemotactic factors is associated with the activation of phosphatidylinositol 3-kinase gamma.
The Journal of biological chemistry 2000;275(31):23636-41.
2000: Nicolas Flamand; S Boudreault; Serge Picard; M Austin; Marc E Surette; Hendrick Plante; E Krump; M J Vallée; C Gilbert; Paul H Naccache; Michel Laviolette; Pierre Borgeat
Adenosine, a potent natural suppressor of arachidonic acid release and leukotriene biosynthesis in human neutrophils.
American journal of respiratory and critical care medicine 2000;161(2 Pt 2):S88-94.
2000: Nathalie Thibault; Danielle Harbour; Pierre Borgeat; Paul H Naccache; Sylvain G Bourgoin
Adenosine receptor occupancy suppresses chemoattractant-induced phospholipase D activity by diminishing membrane recruitment of small GTPases.
Blood 2000;95(2):519-27.
2000: Emmanuelle Rollet-Labelle; Caroline Gilbert; Paul H Naccache
Modulation of human neutrophil responses to CD32 cross-linking by serine/threonine phosphatase inhibitors: cross-talk between serine/threonine and tyrosine phosphorylation.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):1020-8.
1999: Martin G Houle; Paul H Naccache; Sylvain G Bourgoin
Tyrosine kinase-regulated small GTPase translocation and the activation of phospholipase D in HL60 granulocytes.
Journal of leukocyte biology 1999;66(6):1021-30.
1999: A al-Shami; Paul H Naccache
Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Involvement of Jak2 in the stimulation of phosphatidylinositol 3-kinase.
The Journal of biological chemistry 1999;274(9):5333-8.
1999: J Marcil; Danielle Harbour; Martin G Houle; Paul H Naccache; Sylvain G Bourgoin
Monosodium urate-crystal-stimulated phospholipase D in human neutrophils.
The Biochemical journal 1999;337 ( Pt 2)():185-92.
1998: Marc Pouliot; Caroline Gilbert; Pierre Borgeat; Patrice E Poubelle; Sylvain G Bourgoin; C Créminon; J Maclouf; Shaun R McColl; Paul H Naccache
Expression and activity of prostaglandin endoperoxide synthase-2 in agonist-activated human neutrophils.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(12):1109-23.
1998: Philippe A Tessier; Paul H Naccache; K R Diener; Ronald P Gladue; Kuldeep S Neote; Ian Clark-Lewis; Shaun R McColl
Induction of acute inflammation in vivo by staphylococcal superantigens. II. Critical role for chemokines, ICAM-1, and TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(3):1204-11.
1998: Marc Pouliot; Michael J James; Shaun R McColl; Paul H Naccache; Leslie G Cleland
Monosodium urate microcrystals induce cyclooxygenase-2 in human monocytes.
Blood 1998;91(5):1769-76.
1998: Frédéric Barabé; Caroline Gilbert; N Liao; Sylvain G Bourgoin; Paul H Naccache
Crystal-induced neutrophil activation VI. Involvment of FcgammaRIIIB (CD16) and CD11b in response to inflammatory microcrystals.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(2):209-20.
1998: A al-Shami; W Mahanna; Paul H Naccache
Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Selective activation of Jak2, Stat3, and Stat5b.
The Journal of biological chemistry 1998;273(2):1058-63.
1998: M Hachicha; P Rathanaswami; Paul H Naccache; Shaun R McColl
Regulation of chemokine gene expression in human peripheral blood neutrophils phagocytosing microbial pathogens.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):449-54.
1997: Paul H Naccache; Caroline Gilbert; Frédéric Barabé; A al-Shami; W Mahana; Sylvain G Bourgoin
Agonist-specific tyrosine phosphorylation of Cbl in human neutrophils.
Journal of leukocyte biology 1997;62(6):901-10.
1997: Philippe A Tessier; Paul H Naccache; Ian Clark-Lewis; Ronald P Gladue; Kuldeep S Neote; Shaun R McColl
Chemokine networks in vivo: involvement of C-X-C and C-C chemokines in neutrophil extravasation in vivo in response to TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3595-602.
1997: J Marcil; Danielle Harbour; Paul H Naccache; Sylvain G Bourgoin
Human phospholipase D1 can be tyrosine-phosphorylated in HL-60 granulocytes.
The Journal of biological chemistry 1997;272(33):20660-4.
1997: A al-Shami; Caroline Gilbert; Frédéric Barabé; M Gaudry; Paul H Naccache
Preservation of the pattern of tyrosine phosphorylation in human neutrophil lysates.
Journal of immunological methods 1997;202(2):183-91.
1997: A al-Shami; Sylvain G Bourgoin; Paul H Naccache
Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. I. Tyrosine phosphorylation-dependent stimulation of phosphatidylinositol 3-kinase and inhibition by phorbol esters.
Blood 1997;89(3):1035-44.
1997: Shaun R McColl; Paul H Naccache
Calcium mobilization assays.
Methods in enzymology 1997;288():301-9.
1996: B B Damaj; Shaun R McColl; Kuldeep S Neote; N Songqing; K T Ogborn; C A Hébert; Paul H Naccache
Identification of G-protein binding sites of the human interleukin-8 receptors by functional mapping of the intracellular loops.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(12):1426-34.
1996: B B Damaj; Shaun R McColl; Kuldeep S Neote; C A Hébert; Paul H Naccache
Diverging signal transduction pathways activated by interleukin 8 (IL-8) and related chemokines in human neutrophils. IL-8 and Gro-alpha differentially stimulate calcium influx through IL-8 receptors A and B.
The Journal of biological chemistry 1996;271(34):20540-4.
1996: C J Roberge; M Gaudry; Caroline Gilbert; S E Malawista; R de Médicis; A Lussier; Patrice E Poubelle; Paul H Naccache
Paradoxical effects of colchicine on the activation of human neutrophilis by chemotactic factors and inflammatory microcrystal.
Journal of leukocyte biology 1996;59(6):864-71.
1996: B B Damaj; Shaun R McColl; W Mahana; M F Crouch; Paul H Naccache
Physical association of Gi2alpha with interleukin-8 receptors.
The Journal of biological chemistry 1996;271(22):12783-9.
1996: A Richard; Sylvain G Bourgoin; Paul H Naccache; G P L'Heureux; E Krump; Shaun R McColl; G Pelletier
C2-ceramide primes specifically for the superoxide anion production induced by N-formylmethionylleucyl phenylalanine (fMLP) in human neutrophils.
Biochimica et biophysica acta 1996;1299(2):259-66.
1996: PH Reinhardt; Paul H Naccache; Patrice E Poubelle; R de Médicis; M E Kehrli; Paul Kubes
Monosodium urate crystals promote neutrophil adhesion via a CD18-independent and selectin-independent mechanism.
The American journal of physiology 1996;270(1 Pt 1):C31-9.
1995: M Hachicha; Paul H Naccache; Shaun R McColl
Inflammatory microcrystals differentially regulate the secretion of macrophage inflammatory protein 1 and interleukin 8 by human neutrophils: a possible mechanism of neutrophil recruitment to sites of inflammation in synovitis.
The Journal of experimental medicine 1995;182(6):2019-25.
1995: M Gaudry; Caroline Gilbert; Frédéric Barabé; Patrice E Poubelle; Paul H Naccache
Activation of Lyn is a common element of the stimulation of human neutrophils by soluble and particulate agonists.
Blood 1995;86(9):3567-74.
1995: Martin G Houle; Richard A Kahn; Paul H Naccache; Sylvain G Bourgoin
ADP-ribosylation factor translocation correlates with potentiation of GTP gamma S-stimulated phospholipase D activity in membrane fractions of HL-60 cells.
The Journal of biological chemistry 1995;270(39):22795-800.
1995: E Krump; Marc Pouliot; Paul H Naccache; Pierre Borgeat
Leukotriene synthesis in calcium-depleted human neutrophils: arachidonic acid release correlates with calcium influx.
The Biochemical journal 1995;310 ( Pt 2)():681-8.
1995: Reem Al-Daccak; B Damaj; Paul H Naccache; Walid Mourad
Superantigens initiate cognate CD4+ T cell/B cell interactions leading to early activation and proliferation of B cells.
European journal of immunology 1995;25(9):2539-43.
1995: G P L'Heureux; Sylvain G Bourgoin; N Jean; Shaun R McColl; Paul H Naccache
Diverging signal transduction pathways activated by interleukin-8 and related chemokines in human neutrophils: interleukin-8, but not NAP-2 or GRO alpha, stimulates phospholipase D activity.
Blood 1995;85(2):522-31.
1994: Paul H Naccache; N Jean; N W Liao; J M Bator; Shaun R McColl; P Kubes
Regulation of stimulated integrin surface expression in human neutrophils by tyrosine phosphorylation.
Blood 1994;84(2):616-24.
1994: E Rollet; A C Caon; C J Roberge; N W Liao; S E Malawista; Shaun R McColl; Paul H Naccache
Tyrosine phosphorylation in activated human neutrophils. Comparison of the effects of different classes of agonists and identification of the signaling pathways involved.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(1):353-63.
1994: C J Roberge; R de Médicis; J M Dayer; M Rola-Pleszczynski; Paul H Naccache; Patrice E Poubelle
Crystal-induced neutrophil activation. V. Differential production of biologically active IL-1 and IL-1 receptor antagonist.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(11):5485-94.
1993: C J Roberge; M Gaudry; R de Médicis; A Lussier; Patrice E Poubelle; Paul H Naccache
Crystal-induced neutrophil activation. IV. Specific inhibition of tyrosine phosphorylation by colchicine.
The Journal of clinical investigation 1993;92(4):1722-9.
1993: Paul H Naccache; A C Caon; Caroline Gilbert; M Gaudry; C J Roberge; Patrice E Poubelle; S Bourgoin
Inhibition of tyrosine phosphorylation by wortmannin in human neutrophils. Dissociation from its inhibitory effects on phospholipase D.
Laboratory investigation; a journal of technical methods and pathology 1993;69(1):19-23.
1993: M Gaudry; A C Caon; Paul H Naccache
Modulation of the activity and subcellular distribution of protein tyrosine kinases in human neutrophils by phorbol esters.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(8):687-93.
1993: M Gaudry; C J Roberge; R de Médicis; A Lussier; Patrice E Poubelle; Paul H Naccache
Crystal-induced neutrophil activation. III. Inflammatory microcrystals induce a distinct pattern of tyrosine phosphorylation in human neutrophils.
The Journal of clinical investigation 1993;91(4):1649-55.
1993: Paul H Naccache; S Bourgoin; E Plante; C J Roberge; R de Medicis; A Lussier; Patrice E Poubelle
Crystal-induced neutrophil activation. II. Evidence for the activation of a phosphatidylcholine-specific phospholipase D.
Arthritis and rheumatism 1993;36(1):117-25.
1992: S Bourgoin; Patrice E Poubelle; N W Liao; K Umezawa; Pierre Borgeat; Paul H Naccache
Granulocyte-macrophage colony-stimulating factor primes phospholipase D activity in human neutrophils in vitro: role of calcium, G-proteins and tyrosine kinases.
Cellular signalling 1992;4(5):487-500.
1992: B Damaj; Walid Mourad; Paul H Naccache
Superantigen-mediated human monocyte-T lymphocyte interactions are associated with an MHC class II-, TCR/CD3-, and CD4-dependent mobilization of calcium in monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(5):1497-503.
1992: P P McDonald; Shaun R McColl; Paul H Naccache; Pierre Borgeat
Activation of the human neutrophil 5-lipoxygenase by leukotriene B4.
British journal of pharmacology 1992;107(1):226-32.
1992: Caroline Gilbert; M Gaudry; Paul H Naccache
Rapid priming of calcium mobilization and superoxide anion production in human neutrophils by substimulatory concentrations of phorbol esters: a novel role for protein kinase C and tyrosine phosphorylation in the up-modulation of signal transduction.
Cellular signalling 1992;4(5):511-23.
1992: M Gaudry; A C Caon; Caroline Gilbert; S Lille; Paul H Naccache
Evidence for the involvement of tyrosine kinases in the locomotory responses of human neutrophils.
Journal of leukocyte biology 1992;51(2):103-8.
1991: P P McDonald; Shaun R McColl; Paul H Naccache; Pierre Borgeat
Studies on the activation of human neutrophil 5-lipoxygenase induced by natural agonists and Ca2+ ionophore A23187.
The Biochemical journal 1991;280 ( Pt 2)():379-85.
1991: Paul H Naccache; A C Caon; Caroline Gilbert; G Chouinard; Shaun R McColl
Pertussis toxin selectively interferes with the responses of the HL-60 human promyelocytic cell line to dimethylsulfoxide.
Blood 1991;78(10):2534-41.
1991: Shaun R McColl; J F DiPersio; A C Caon; P Ho; Paul H Naccache
Involvement of tyrosine kinases in the activation of human peripheral blood neutrophils by granulocyte-macrophage colony-stimulating factor.
Blood 1991;78(7):1842-52.
1991: C J Roberge; J Grassi; R De Médicis; Y Frobert; A Lussier; Paul H Naccache; Patrice E Poubelle
Crystal-neutrophil interactions lead to interleukin-1 synthesis.
Agents and actions 1991;34(1-2):38-41.
1991: Paul H Naccache; M Grimard; C J Roberge; Caroline Gilbert; A Lussier; R de Médicis; Patrice E Poubelle
Crystal-induced neutrophil activation. I. Initiation and modulation of calcium mobilization and superoxide production by microcrystals.
Arthritis and rheumatism 1991;34(3):333-42.
1991: Shaun R McColl; E Krump; Paul H Naccache; Patrice E Poubelle; P Braquet; M Braquet; Pierre Borgeat
Granulocyte-macrophage colony-stimulating factor increases the synthesis of leukotriene B4 by human neutrophils in response to platelet-activating factor. Enhancement of both arachidonic acid availability and 5-lipoxygenase activation.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(4):1204-11.
1990: Paul H Naccache; Caroline Gilbert; A C Caon; M Gaudry; C K Huang; V A Bonak; K Umezawa; Shaun R McColl
Selective inhibition of human neutrophil functional responsiveness by erbstatin, an inhibitor of tyrosine protein kinase.
Blood 1990;76(10):2098-104.
1990: Shaun R McColl; D Beauseigle; C Gilbert; Paul H Naccache
Priming of the human neutrophil respiratory burst by granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha involves regulation at a post-cell surface receptor level. Enhancement of the effect of agents which directly activate G proteins.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(9):3047-53.
1990: S Bourgoin; E Plante; M Gaudry; Paul H Naccache; Pierre Borgeat; Patrice E Poubelle
Involvement of a phospholipase D in the mechanism of action of granulocyte-macrophage colony-stimulating factor (GM-CSF): priming of human neutrophils in vitro with GM-CSF is associated with accumulation of phosphatidic acid and diradylglycerol.
The Journal of experimental medicine 1990;172(3):767-77.
1990: Shaun R McColl; E Krump; P P McDonald; M Braquet; Paul H Naccache; Pierre Borgeat
Enhancement of platelet-activating factor-induced leukotriene synthesis in neutrophils by granulocyte-macrophage colony-stimulating factor (GM-CSF): studies on the mechanism of action of GM-CSF.
Journal of lipid mediators 1990;2 Suppl():S119-27.
1989: S Therrien; Paul H Naccache
Guanine nucleotide-induced polymerization of actin in electropermeabilized human neutrophils.
The Journal of cell biology 1989;109(3):1125-32.
1989: Shaun R McColl; E Krump; Paul H Naccache; A C Caon; Pierre Borgeat
Activation of the human neutrophil 5-lipoxygenase by exogenous arachidonic acid: involvement of pertussis toxin-sensitive guanine nucleotide-binding proteins.
British journal of pharmacology 1989;97(4):1265-73.
1989: Shaun R McColl; E Krump; Paul H Naccache; Pierre Borgeat
Enhancement of human neutrophil leukotriene synthesis by human granulocyte-macrophage colony-stimulating factor.
Agents and actions 1989;27(3-4):465-8.
1989: Patrice E Poubelle; S Bourgoin; Paul H Naccache; Pierre Borgeat
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and opsonization synergistically enhance leukotriene B4 (LTB4) synthesis induced by phagocytosis in human neutrophils.
Agents and actions 1989;27(3-4):388-90.
1989: Paul H Naccache; Shaun R McColl; A C Caon; Pierre Borgeat
Arachidonic acid-induced mobilization of calcium in human neutrophils: evidence for a multicomponent mechanism of action.
British journal of pharmacology 1989;97(2):461-8.
1989: Paul H Naccache; S Therrien; A C Caon; N Liao; Caroline Gilbert; Shaun R McColl
Chemoattractant-induced cytoplasmic pH changes and cytoskeletal reorganization in human neutrophils. Relationship to the stimulated calcium transients and oxidative burst.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(7):2438-44.
1988: Paul H Naccache; N Faucher; A C Caon; Shaun R McColl
Propionic acid-induced calcium mobilization in human neutrophils.
Journal of cellular physiology 1988;136(1):118-24.
1988: Paul H Naccache; N Faucher; Pierre Borgeat; J C Gasson; J F DiPersio
Granulocyte-macrophage colony-stimulating factor modulates the excitation-response coupling sequence in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(10):3541-6.
1988: Paul H Naccache; N Faucher; S Therrien; Pierre Borgeat
Calcium mobilization, actin polymerization and right-angle light scatter responses to leukotriene B4, 12(R)- and 12(S)-hydroxyeicosatetraenoic acid in human neutrophils.
Life sciences 1988;42(6):727-33.
1987: Patrice E Poubelle; R De Medicis; Paul H Naccache
Monosodium urate and calcium pyrophosphate crystals differentially activate the excitation-response coupling sequence of human neutrophils.
Biochemical and biophysical research communications 1987;149(2):649-57.
1987: Paul H Naccache
Signals for actin polymerization in neutrophils.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1987;41(6):297-304.