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Parimala Nacharaju

Research Profile

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Missense Mutation

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Publications

TOP 3
Surapong Chatpun; Parimala Nacharaju; Pedro Cabrales
Improving cardiac function with new-generation plasma volume expanders.
Jason Chouake; Karin Blecher-Paz; Joel M Friedman; Philip Gialanella; Allison Kutner; Joy Makdisi; Parimala Nacharaju; Joshua D Nosanchuk; David A Sanchez; David Schairer; Chaim Tuckman-Vernon; Adam J Friedman
Nitrosoglutathione generating nitric oxide nanoparticles as an improved strategy for combating Pseudomonas aeruginosa-infected wounds.
Karin Blecher; Jason Chouake; Alan Alfieri; Joel M Friedman; Chandan Guha; Luis R Martinez; Parimala Nacharaju; Joshua D Nosanchuk; David Schairer; Chaim Tuckman-Vernon; Adam J Friedman
Nitric oxide-releasing nanoparticles accelerate wound healing in NOD-SCID mice.

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All Publications

2013: Surapong Chatpun; Parimala Nacharaju; Pedro Cabrales
Improving cardiac function with new-generation plasma volume expanders.
The American journal of emergency medicine 2013;31(1):54-63.
2012: Jason Chouake; Karin Blecher-Paz; Joel M Friedman; Philip Gialanella; Allison Kutner; Joy Makdisi; Parimala Nacharaju; Joshua D Nosanchuk; David A Sanchez; David Schairer; Chaim Tuckman-Vernon; Adam J Friedman
Nitrosoglutathione generating nitric oxide nanoparticles as an improved strategy for combating Pseudomonas aeruginosa-infected wounds.
Journal of drugs in dermatology : JDD 2012;11(12):1471-7.
2012: Karin Blecher; Jason Chouake; Alan Alfieri; Joel M Friedman; Chandan Guha; Luis R Martinez; Parimala Nacharaju; Joshua D Nosanchuk; David Schairer; Chaim Tuckman-Vernon; Adam J Friedman
Nitric oxide-releasing nanoparticles accelerate wound healing in NOD-SCID mice.
Nanomedicine : nanotechnology, biology, and medicine 2012;8(8):1364-71.
2012: Parimala Nacharaju; Chaim Tuckman-Vernon; Keith E Maier; Pedro Cabrales; Jason Chouake; Adam Friedman; Joel M Friedman
A nanoparticle delivery vehicle for S-nitroso-N-acetyl cysteine: sustained vascular response.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2012;27(3):150-60.
2012: David Schairer; Karin Blecher; Jason Chouake; Joel M Friedman; Philip Gialanella; Luis R Martinez; Parimala Nacharaju; Joshua D Nosanchuk; Adam J Friedman
Nitric oxide nanoparticles: pre-clinical utility as a therapeutic for intramuscular abscesses.
Virulence 2012;3(1):62-7.
2011: Adam J Friedman; Joel Mitchel Friedman; Philip Gialanella; Luis R Martinez; Parimala Nacharaju; David Sanchez; David Schairer; Chaim Tuckman-Vernon; Karin Blecher; Joshua D Nosanchuk
Improved antimicrobial efficacy with nitric oxide releasing nanoparticle generated S-nitrosoglutathione.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2011;25(4):381-6.
2011: Pedro Cabrales; George Han; Parimala Nacharaju; Adam J Friedman; Joel Mitchel Friedman
Reversal of hemoglobin-induced vasoconstriction with sustained release of nitric oxide.
American journal of physiology. Heart and circulatory physiology 2011;300(1):H49-56.
2010: Pedro Cabrales; George Han; Camille Roche; Parimala Nacharaju; Adam J Friedman; Joel Mitchel Friedman
Sustained release nitric oxide from long-lived circulating nanoparticles.
Free radical biology & medicine 2010;49(4):530-8.
2009: ranjit sahu; Parimala Nacharaju; Belur N Manjula; Seetharama A Acharya
Induced plasma expander-like properties as a function of PEG-chains on extension arm facilitated PEGylation of albumin: "mushroom to brush-like" conformational transition of the PEG-albumin conjugate.
Artificial cells, blood substitutes, and immobilization biotechnology 2009;37(6):245-56.
2008: K Ananda; Parimala Nacharaju; Paul K Smith; Seetharama A Acharya; Belur N Manjula
Analysis of functionalization of methoxy-PEG as maleimide-PEG.
Analytical biochemistry 2008;374(2):231-42.
2007: Parimala Nacharaju; Joel Mitchel Friedman; Muthuchidambaram Prabhakaran; Seetharama A Acharya; Belur N Manjula
Combining the influence of two low O2 affinity-inducing chemical modifications of the central cavity of hemoglobin.
Biochemistry 2007;46(15):4554-64.
2007: Parimala Nacharaju; Belur N Manjula; Seetharama A Acharya
Thiolation mediated pegylation platform to generate functional universal red blood cells.
Artificial cells, blood substitutes, and immobilization biotechnology 2007;35(1):107-18.
2006: Nanae Hangai-Hoger; Parimala Nacharaju; Belur N Manjula; Pedro Cabrales; Amy Tsai; Seetharama A Acharya; Marcos Intaglietta
Microvascular effects following treatment with polyethylene glycol-albumin in lipopolysaccharide-induced endotoxemia.
Critical care medicine 2006;34(1):108-17.
2005: Pedro Cabrales; Parimala Nacharaju; Belur N Manjula; Amy Tsai; Seetharama A Acharya; Marcos Intaglietta
Early difference in tissue pH and microvascular hemodynamics in hemorrhagic shock resuscitation using polyethylene glycol-albumin- and hydroxyethyl starch-based plasma expanders.
Shock (Augusta, Ga.) 2005;24(1):66-73.
2005: Parimala Nacharaju; Fouad N Boctor; Belur N Manjula; Seetharama A Acharya
Surface decoration of red blood cells with maleimidophenyl-polyethylene glycol facilitated by thiolation with iminothiolane: an approach to mask A, B, and D antigens to generate universal red blood cells.
Transfusion 2005;45(3):374-83.
2001: Eileen H Bigio; Anne M Lipton; Shu-Hui C. Yen; Michael Hutton; M Baker; Parimala Nacharaju; Charles L White; Peter Davies; W Lin; dennis dickson
Frontal lobe dementia with novel tauopathy: sporadic multiple system tauopathy with dementia.
Journal of neuropathology and experimental neurology 2001;60(4):328-41.
2000: Jada Lewis; Eileen McGowan; J Rockwood; Heather L Melrose; Parimala Nacharaju; M van Slegtenhorst; Katrina Gwinn-Hardy; M Paul Murphy; Matt Baker; X Yu; karen duff; John Hardy; A Corral; Wen-Lang Lin; Shu-Hui C. Yen; dennis dickson; Peter Davies; Michael Hutton
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein.
Nature genetics 2000;25(4):402-5.
2000: Michael DeTure; Li-Wen Ko; S Yen; Parimala Nacharaju; Colin Easson; Jada Lewis; M van Slegtenhorst; Michael Hutton; Shu-Hui C. Yen
Missense tau mutations identified in FTDP-17 have a small effect on tau-microtubule interactions.
Brain research 2000;853(1):5-14.
1999: S Yen; Colin Easson; Parimala Nacharaju; Michael Hutton; Shu-Hui C. Yen
FTDP-17 tau mutations decrease the susceptibility of tau to calpain I digestion.
FEBS letters 1999;461(1-2):91-5.
1999: Shu-Hui C. Yen; Michael Hutton; Michael DeTure; Li-Wen Ko; Parimala Nacharaju
Fibrillogenesis of tau: insights from tau missense mutations in FTDP-17.
Brain pathology (Zurich, Switzerland) 1999;9(4):695-705.
1999: Li-Wen Ko; E C Ko; Parimala Nacharaju; W K Liu; E Chang; A Kenessey; Shu-Hui C. Yen
An immunochemical study on tau glycation in paired helical filaments.
Brain research 1999;830(2):301-13.
1999: Parimala Nacharaju; Jada Lewis; Colin Easson; S Yen; J Hackett; Michael Hutton; Shu-Hui C. Yen
Accelerated filament formation from tau protein with specific FTDP-17 missense mutations.
FEBS letters 1999;447(2-3):195-9.
1997: A Kenessey; Parimala Nacharaju; Li-Wen Ko; Shu-Hui C. Yen
Degradation of tau by lysosomal enzyme cathepsin D: implication for Alzheimer neurofibrillary degeneration.
Journal of neurochemistry 1997;69(5):2026-38.
1997: Parimala Nacharaju; R P Roy; S P White; Ronald L Nagel; Seetharama A Acharya
Inhibition of sickle beta-chain (betaS)-dependent polymerization by nonhuman alpha-chains. A superinhibitory mouse-horse chimeric alpha-chain.
The Journal of biological chemistry 1997;272(44):27869-76.
1997: Parimala Nacharaju; Li-Wen Ko; Shu-Hui C. Yen
Characterization of in vitro glycation sites of tau.
Journal of neurochemistry 1997;69(4):1709-19.
1995: R P Roy; Parimala Nacharaju; Ronald L Nagel; Seetharama A Acharya
Symmetric interspecies hybrids of mouse and human hemoglobin: molecular basis of their abnormal oxygen affinity.
Journal of protein chemistry 1995;14(2):81-8.
1992: Parimala Nacharaju; Seetharama A Acharya
Amadori rearrangement potential of hemoglobin at its glycation sites is dependent on the three-dimensional structure of protein.
Biochemistry 1992;31(50):12673-9.