Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
Florian Nachon
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Chemicals & Drugs
Concepts & Ideas
Phenomena
Procedures
Genes & Molecular Sequences
Living Beings
Sign-in to see full Profile
Network (preview)
26
Masson, Patrick
20
Lockridge, Oksana
16
Schopfer, Lawrence
10
Froment, Marie-Thérèse
7
Nicolet, Yvain
4
Fontecilla-Camps, Juan
3
Rochu, Daniel
3
Li, Bin
3
Gillon, Emilie
3
Goeldner, Maurice
3
Debouzy, Jean-Claude
2
Asojo, Oluwatoyin
2
Bartels, Cynthia
2
Borgstahl, Gloria
2
Colletier, Jacques-Philippe
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of Florian Nachon (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2009: Gilley Cynthia; MacDonald Mary; Nachon Florian; Schopfer Lawrence M; Zhang Jun; Cashman John R; Lockridge Oksana
Nerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase.
Chemical research in toxicology 2009;22(10):1680-8.
-
2009: Follot Sébastien; Debouzy Jean-Claude; Crouzier David; Enguehard-Gueiffier Cécile; Gueiffier Alain; Nachon Florian; Lefebvre Bertrand; Fauvelle Florence
Physicochemical properties and membrane interactions of anti-apoptotic derivatives 2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine depending on the hydroxyalkylamino side chain length and conformation: an NMR and ESR study.
European journal of medicinal chemistry 2009;44(9):3509-18.
-
2009: Carletti Eugénie; Jacquamet Lilian; Loiodice Mélanie; Rochu Daniel; Masson Patrick; Nachon Florian
Update on biochemical properties of recombinant Pseudomonas diminuta phosphotriesterase.
Journal of enzyme inhibition and medicinal chemistry 2009;24(4):1045-55.
-
2009: Grigoryan Hasmik; Li Bin; Anderson Erica K; Xue Weihua; Nachon Florian; Lockridge Oksana; Schopfer Lawrence M
Covalent binding of the organophosphorus agent FP-biotin to tyrosine in eight proteins that have no active site serine.
Chemico-biological interactions 2009;180(3):492-8.
-
2009: Ronco Cyril; Sorin Geoffroy; Nachon Florian; Foucault Richard; Jean Ludovic; Romieu Anthony; Renard Pierre-Yves
Synthesis and structure-activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors.
Bioorganic & medicinal chemistry 2009;17(13):4523-36.
-
2009: Carletti Eugénie; Aurbek Nadine; Gillon Emilie; Loiodice Mélanie; Nicolet Yvain; Fontecilla-Camps Juan-Carlos; Masson Patrick; Thiermann Horst; Nachon Florian; Worek Franz
Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
The Biochemical journal 2009;421(1):97-106.
-
2009: Masson Patrick; Carletti Eugénie; Nachon Florian
Structure, activities and biomedical applications of human butyrylcholinesterase.
Protein and peptide letters 2009;16(10):1215-24.
-
2008: Carletti Eugénie; Li He; Li Bin; Ekström Fredrik; Nicolet Yvain; Loiodice Mélanie; Gillon Emilie; Froment Marie T; Lockridge Oksana; Schopfer Lawrence M; Masson Patrick; Nachon Florian
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation.
Journal of the American Chemical Society 2008;130(47):16011-20.
-
2008: Ding Shi-Jian; Carr John; Carlson James E; Tong Larry; Xue Weihua; Li Yifeng; Schopfer Lawrence M; Li Bin; Nachon Florian; Asojo Oluwatoyin; Thompson Charles M; Hinrichs Steven H; Masson Patrick; Lockridge Oksana
Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin.
Chemical research in toxicology 2008;21(9):1787-94.
-
2008: Masson Patrick; Nachon Florian; Broomfield Clarence A; Lenz David E; Verdier Laurent; Schopfer Lawrence M; Lockridge Oksana
A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters.
Chemico-biological interactions 2008;175(1-3):273-80.
-
2008: Masson Patrick; Froment Marie-Thérèse; Gillon Emilie; Nachon Florian; Lockridge Oksana; Schopfer Lawrence M
Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters.
The FEBS journal 2008;275(10):2617-31.
-
2008: Nachon Florian; Stojan Jure; Fournier Didier
Insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge by enlarging a back channel.
The FEBS journal 2008;275(10):2659-64.
-
2008: Mikami Liya R; Wieseler Stacy; Souza Ricardo L R; Schopfer Lawrence M; Nachon Florian; Lockridge Oksana; Chautard-Freire-Maia Eleidi A
Five new naturally occurring mutations of the BCHE gene and frequencies of 12 butyrylcholinesterase alleles in a Brazilian population.
Pharmacogenetics and genomics 2008;18(3):213-8.
-
2008: Li Bin; Nachon Florian; Froment Marie-Thérèse; Verdier Laurent; Debouzy Jean-Claude; Brasme Bernardo; Gillon Emilie; Schopfer Lawrence M; Lockridge Oksana; Masson Patrick
Binding and hydrolysis of soman by human serum albumin.
Chemical research in toxicology 2008;21(2):421-31.
-
2007: Colletier Jacques-Philippe; Royant Antoine; Specht Alexandre; Sanson Benoît; Nachon Florian; Masson Patrick; Zaccai Giuseppe; Sussman Joel L; Goeldner Maurice; Silman Israel; Bourgeois Dominique; Weik Martin
Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 11):1115-28.
-
2007: Li He; Schopfer Lawrence M; Nachon Florian; Froment Marie-Thérèse; Masson Patrick; Lockridge Oksana
Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry.
Toxicological sciences : an official journal of the Society of Toxicology 2007;100(1):136-45.
-
2007: Masson Patrick; Froment Marie-Thérèse; Gillon Emilie; Nachon Florian; Darvesh Sultan; Schopfer Lawrence M
Kinetic analysis of butyrylcholinesterase-catalyzed hydrolysis of acetanilides.
Biochimica et biophysica acta 2007;1774(9):1139-47.
-
2007: Poyot T; Nachon F; Rochu D; Fournier D; Masson P
[Enzyme optimization, mutagenesis and directed evolution]
Annales pharmaceutiques françaises 2007;65(2):119-25.
-
2007: Masson Patrick; Nachon Florian; Rochu Daniel
[Engineering of catalytic bioscavengers of organophosphorus compounds]
Bulletin de l'Académie nationale de médecine 2007;191(1):95-111; discussion 112.
-
2007: Masson Patrick; Froment Marie-Thérèse; Gillon Emilie; Nachon Florian; Lockridge Oksana; Schopfer Lawrence M
Hydrolysis of oxo- and thio-esters by human butyrylcholinesterase.
Biochimica et biophysica acta 2007;1774(1):16-34.
-
2006: Poyot Thomas; Nachon Florian; Froment Marie-Thérèse; Loiodice Mélanie; Wieseler Stacy; Schopfer Lawrence M; Lockridge Oksana; Masson Patrick
Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters.
Biochimica et biophysica acta 2006;1764(9):1470-8.
-
2006: Colletier Jacques Ph; Sanson Benoît; Nachon Florian; Gabellieri Emanuele; Fattorusso Caterina; Campiani Giuseppe; Weik Martin
Conformational flexibility in the peripheral site of Torpedo californica acetylcholinesterase revealed by the complex structure with a bifunctional inhibitor.
Journal of the American Chemical Society 2006;128(14):4526-7.
-
2005: Nachon F; Asojo O A; Borgstahl G; Masson P; Lockridge O
Structural data on the aging of diethylphosphoryl-butyrylcholinesterase.
Chemico-biological interactions 2005;157-158():408-9.
-
2005: Masson Patrick; Schopfer Lawrence M; Froment Marie-Thérèse; Debouzy Jean-Claude; Nachon Florian; Gillon Emilie; Lockridge Oksana; Hrabovska Anna; Goldstein Boris N
Hysteresis of butyrylcholinesterase in the approach to steady-state kinetics.
Chemico-biological interactions 2005;157-158():143-52.
-
2005: Tormos Jose R; Wiley Kenneth L; Seravalli Javier; Nachon Florian; Masson Patrick; Nicolet Yvain; Quinn Daniel M
The reactant state for substrate-activated turnover of acetylthiocholine by butyrylcholinesterase is a tetrahedral intermediate.
Journal of the American Chemical Society 2005;127(42):14538-9.
-
2005: Nachon Fl; Nicolet Y; Masson P
[Butyrylcholinesterase: 3D structure, catalytic mechanisms]
Annales pharmaceutiques françaises 2005;63(3):194-206.
-
2005: Nachon Florian; Asojo Oluwatoyin A; Borgstahl Gloria E O; Masson Patrick; Lockridge Oksana
Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging.
Biochemistry 2005;44(4):1154-62.
-
2004: Wang Yuxia; Schopfer Lawrence M; Duysen Ellen G; Nachon Florian; Masson Patrick; Lockridge Oksana
Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants.
Analytical biochemistry 2004;329(1):131-8.
-
2004: Masson Patrick; Bec Nicole; Froment Marie-Thérèse; Nachon Florian; Balny Claude; Lockridge Oksana; Schopfer Lawrence M
Rate-determining step of butyrylcholinesterase-catalyzed hydrolysis of benzoylcholine and benzoylthiocholine. Volumetric study of wild-type and D70G mutant behavior.
European journal of biochemistry / FEBS 2004;271(10):1980-90.
-
2003: Nicolet Yvain; Lockridge Oksana; Masson Patrick; Fontecilla-Camps Juan C; Nachon Florian
Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products.
The Journal of biological chemistry 2003;278(42):41141-7.
-
2003: Loudwig Sandra; Nicolet Yvain; Masson Patrick; Fontecilla-Camps Juan C; Bon Suzanne; Nachon Florian; Goeldner Maurice
Photoreversible inhibition of cholinesterases: catalytic serine-labeled caged butyrylcholinesterase.
Chembiochem : a European journal of chemical biology 2003;4(8):762-7.
-
2003: Masson Patrick; Nachon Florian; Bartels Cynthia F; Froment Marie-Therese; Ribes Fabien; Matthews Cedric; Lockridge Oksana
High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine.
European journal of biochemistry / FEBS 2003;270(2):315-24.
-
2002: Masson Patrick; Schopfer Lawrence M; Bartels Cynthia F; Froment Marie-Thérèse; Ribes Fabien; Nachon Florian; Lockridge Oksana
Substrate activation in acetylcholinesterase induced by low pH or mutation in the pi-cation subsite.
Biochimica et biophysica acta 2002;1594(2):313-24.
-
2002: Nachon Florian; Nicolet Yvain; Viguié Nathalie; Masson Patrick; Fontecilla-Camps Juan C; Lockridge Oksana
Engineering of a monomeric and low-glycosylated form of human butyrylcholinesterase: expression, purification, characterization and crystallization.
European journal of biochemistry / FEBS 2002;269(2):630-7.
-
1998: Nachon F; Ehret-Sabatier L; Loew D; Colas C; van Dorsselaer A; Goeldner M
Trp82 and Tyr332 are involved in two quaternary ammonium binding domains of human butyrylcholinesterase as revealed by photoaffinity labeling with [3H]DDF.
Biochemistry 1998;37(29):10507-13.
Sign-in to see more
