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T Nadai

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Takeyuki Kohno; H Tanaka; Kazuhito Watabe; Shinji Yamashita; Hitoshi Sezaki; T Nadai; Yohko Sugie; T Ogouchi
Assessment of mucosal immune response in genitourinary tract using urine.
Y Taki; Toshiyasu Sakane; T Nadai; Hitoshi Sezaki; Gordon L Amidon; P Langguth; Shinji Yamashita
First-pass metabolism of peptide drugs in rat perfused liver.
M Takagi; Y Taki; Toshiyasu Sakane; T Nadai; Hitoshi Sezaki; N Oku; Shinji Yamashita
A new interpretation of salicylic acid transport across the lipid bilayer: implications of pH-dependent but not carrier-mediated absorption from the gastrointestinal tract.

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All Publications

1999: Takeyuki Kohno; H Tanaka; Kazuhito Watabe; Shinji Yamashita; Hitoshi Sezaki; T Nadai; Yohko Sugie; T Ogouchi
Assessment of mucosal immune response in genitourinary tract using urine.
Microbiology and immunology 1999;43(3):253-8.
1998: Y Taki; Toshiyasu Sakane; T Nadai; Hitoshi Sezaki; Gordon L Amidon; P Langguth; Shinji Yamashita
First-pass metabolism of peptide drugs in rat perfused liver.
The Journal of pharmacy and pharmacology 1998;50(9):1013-8.
1998: M Takagi; Y Taki; Toshiyasu Sakane; T Nadai; Hitoshi Sezaki; N Oku; Shinji Yamashita
A new interpretation of salicylic acid transport across the lipid bilayer: implications of pH-dependent but not carrier-mediated absorption from the gastrointestinal tract.
The Journal of pharmacology and experimental therapeutics 1998;285(3):1175-80.
1997: Shinji Yamashita; Y Tanaka; Y Endoh; Y Taki; Toshiyasu Sakane; T Nadai; Hitoshi Sezaki
Analysis of drug permeation across Caco-2 monolayer: implication for predicting in vivo drug absorption.
Pharmaceutical research 1997;14(4):486-91.
1997: K Nakanishi; T Masukawa; T Nadai; K Yoshii; S Okada; K Miyajima
Sustained release of flufenamic acid from a drug-triacetyl-beta-cyclodextrin complex.
Biological & pharmaceutical bulletin 1997;20(1):66-70.
1996: Y Tsume; Y Taki; T Sakane; T Nadai; H Sezaki; K Watabe; T Kohno; S Yamashita
Quantitative evaluation of the gastrointestinal absorption of protein into the blood and lymph circulation.
Biological & pharmaceutical bulletin 1996;19(10):1332-7.
1995: Y Taki; Toshiyasu Sakane; T Nadai; Hitoshi Sezaki; Gordon L Amidon; P Langguth; Shinji Yamashita
Gastrointestinal absorption of peptide drug: quantitative evaluation of the degradation and the permeation of metkephamid in rat small intestine.
The Journal of pharmacology and experimental therapeutics 1995;274(1):373-7.
1995: Toshiyasu Sakane; M Akizuki; Y Taki; Shinji Yamashita; Hitoshi Sezaki; T Nadai
Direct drug transport from the rat nasal cavity to the cerebrospinal fluid: the relation to the molecular weight of drugs.
The Journal of pharmacy and pharmacology 1995;47(5):379-81.
1995: Y Tanaka; Y Taki; Toshiyasu Sakane; T Nadai; Hitoshi Sezaki; Shinji Yamashita
Characterization of drug transport through tight-junctional pathway in Caco-2 monolayer: comparison with isolated rat jejunum and colon.
Pharmaceutical research 1995;12(4):523-8.
1994: Shinji Yamashita; M Yoshida; Y Taki; Toshiyasu Sakane; T Nadai
Kinetic analysis of the drug permeation process across the intestinal epithelium.
Pharmaceutical research 1994;11(11):1646-51.
1994: K Nakanishi; Tohru Masukawa; M Masada; T Nadai
Improvement of the rectal bioavailability of latamoxef sodium by adjuvants following administration of a suppository.
Biological & pharmaceutical bulletin 1994;17(11):1496-500.
1994: Toshiyasu Sakane; M Akizuki; Shinji Yamashita; Hitoshi Sezaki; T Nadai
Direct drug transport from the rat nasal cavity to the cerebrospinal fluid: the relation to the dissociation of the drug.
The Journal of pharmacy and pharmacology 1994;46(5):378-9.
1992: K Nakanishi; T Nadai; M Masada; K Miyajima
Effect of cyclodextrins on biological membrane. II. Mechanism of enhancement on the intestinal absorption of non-absorbable drug by cyclodextrins.
Chemical & pharmaceutical bulletin 1992;40(5):1252-6.
1991: Toshiyasu Sakane; M Akizuki; Shinji Yamashita; T Nadai; M Hashida; Hitoshi Sezaki
The transport of a drug to the cerebrospinal fluid directly from the nasal cavity: the relation to the lipophilicity of the drug.
Chemical & pharmaceutical bulletin 1991;39(9):2456-8.
1991: Toshiyasu Sakane; M Nakatsu; A Yamamoto; M Hashida; Hitoshi Sezaki; Shinji Yamashita; T Nadai
Assessment of drug disposition in the perfused rat brain by statistical moment analysis.
Pharmaceutical research 1991;8(6):683-9.
1991: Toshiyasu Sakane; M Akizuki; M Yoshida; Shinji Yamashita; T Nadai; M Hashida; Hitoshi Sezaki
Transport of cephalexin to the cerebrospinal fluid directly from the nasal cavity.
The Journal of pharmacy and pharmacology 1991;43(6):449-51.
1990: K Nakanishi; M Masada; T Nadai
Improvement by adjuvants on the rectal bioavailability of non-absorbable drugs following administration of suppository.
Journal of pharmacobio-dynamics 1990;13(12):760-5.
1990: Shinji Yamashita; M Masada; T Nadai; T Kimura
Effect of adjuvants on charge-selective permeability and electrical resistance of rat jejunal membrane.
Journal of pharmaceutical sciences 1990;79(7):579-83.
1990: K Nakanishi; T Nadai; M Masada; K Miyajima
Effect of cyclodextrins on biological membrane. I. Effect of cyclodextrins on the absorption of a non-absorbable drug from rat small intestine and rectum.
Chemical & pharmaceutical bulletin 1990;38(6):1684-7.
1989: S Yamashita; Y Suda; M Masada; T Nadai; M Sumi
5-Fluorouracil derivatives with serum protein binding potencies.
Chemical & pharmaceutical bulletin 1989;37(10):2861-3.
1989: K Nakanishi; M Masada; T Nadai; K Miyajima
Effect of the interaction of drug-beta-cyclodextrin complex with bile salts on the drug absorption from rat small intestinal lumen.
Chemical & pharmaceutical bulletin 1989;37(1):211-4.
1988: S Yamashita; M Takahashi; M Masada; T Nadai; A Kobayashi; Y Kurosaki; T Nakayama; T Kimura
Effect of experimental acute renal failure on barriers to permeation of a polar drug in rat jejunum: an electrophysiological analysis.
Chemical & pharmaceutical bulletin 1988;36(7):2538-43.
1987: S Yamashita; H Saitoh; K Abe; K Nakanishi; M Masada; T Nadai; T Kimura
Effects of sodium or glucose exclusion from the incubation medium on drug transfer across rat jejunal membrane in vitro: an electrophysiological study.
Chemical & pharmaceutical bulletin 1987;35(8):3382-9.
1987: Shinji Yamashita; H Saitoh; K Nakanishi; M Masada; T Nadai; T Kimura
Effects of diclofenac sodium and disodium ethylenediaminetetraacetate on electrical parameters of the mucosal membrane and their relation to the permeability enhancing effects in the rat jejunum.
The Journal of pharmacy and pharmacology 1987;39(8):621-6.
1986: K Nakanishi; M Masada; T Nadai
Effect of nonsteroidal anti-inflammatory drugs on the absorption of macromolecular drugs in rat rectum.
Chemical & pharmaceutical bulletin 1986;34(6):2628-31.
1986: M Masada; K Suzuki; S Kikuta; S Yamashita; K Nakanishi; T Nadai; Y Igarashi; T Noguchi
Regional distribution and elimination kinetics of imipramine in rat brain after a single intraperitoneal administration.
Chemical & pharmaceutical bulletin 1986;34(5):2173-7.
1986: S Yamashita; Y Yamazaki; M Masada; T Nadai; T Kimura; H Sezaki
Investigations of influx and accumulation processes of beta-lactam antibiotics and their role in the transmural transfer across rat jejunum.
Journal of pharmacobio-dynamics 1986;9(4):368-74.
1986: M Masada; K Suzuki; S Kikuta; S Yamashita; K Nakanishi; T Nadai; Y Igarashi; T Noguchi
Regional distribution and elimination kinetics of imipramine in rat brain after multiple dosages.
Chemical & pharmaceutical bulletin 1986;34(2):927-30.
1985: S Yamashita; H Saitoh; K Nakanishi; M Masada; T Nadai; T Kimura
Characterization of enhanced intestinal permeability; electrophysiological study on the effects of diclofenac and ethylenediaminetetraacetic acid.
The Journal of pharmacy and pharmacology 1985;37(7):512-3.
1984: M Masada; K Suzuki; S Kikuta; S Yamashita; K Nakanishi; T Nadai; Y Igarashi; T Noguchi
Regional distribution and elimination kinetics of imipramine in rat brain.
Chemical & pharmaceutical bulletin 1984;32(11):4678-81.
1984: K Nakanishi; H Saitoh; M Masada; A Tatematsu; T Nadai
Mechanism of the enhancement of rectal permeability of drugs by nonsteroidal anti-inflammatory drugs.
Chemical & pharmaceutical bulletin 1984;32(8):3187-93.
1984: K Nakanishi; A Ogata; M Masada; T Nadai
Effect of nonsteroidal anti-inflammatory drugs on the permeability of the rectal mucosa.
Chemical & pharmaceutical bulletin 1984;32(5):1956-66.
1984: S Yamashita; Y Yamazaki; M Mizuno; M Masada; T Nadai; T Kimura; H Sezaki
Further investigations on the transport mechanism of cephalexin and ampicillin across rat jejunum.
Journal of pharmacobio-dynamics 1984;7(4):227-33.
1984: K Nakanishi; M Masada; T Nadai
Effect of pharmaceutical adjuvants on the rectal permeability to drugs. IV. Effect of pharmaceutical adjuvants on the rectal permeability to macromolecular compounds in the rat.
Chemical & pharmaceutical bulletin 1984;32(4):1628-32.
1983: K Nakanishi; M Masada; T Nadai
Effect of pharmaceutical adjuvants on the rectal permeability of drugs. III. Effect of repeated administration and recovery of the permeability.
Chemical & pharmaceutical bulletin 1983;31(11):4161-6.
1983: K Nakanishi; M Masada; T Nadai
Effect of pharmaceutical adjuvants on the rectal permeability of drugs. II. Effect of Tween-type surfactants on the permeability of drugs in the rat rectum.
Chemical & pharmaceutical bulletin 1983;31(9):3255-63.
1982: K Nakanishi; S Miyazaki; M Masada; T Nadai
[Effect of pharmaceutical adjuvants on the rectal permeability of drugs. I. Effect of pharmaceutical additives on the permeability of sulfaguanidine from the rat rectum].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1982;102(12):1133-40.