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Eishi Nagai

Research Profile

Disorders

Chemicals & Drugs

Anatomy

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Physiology

Gene Expression Regulation, Neoplastic

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Eishi Nagai; Kohei Nakata; Kenoki Ohuchida; Shuji Shimizu; Ryo Maeyama; Yoshihiro Miyasaka; Hiroki Toma; Masao Tanaka
Feasibility and safety of intracorporeal esophagojejunostomy after laparoscopic total gastrectomy: Inverted T-shaped anastomosis using linear staplers.
Kenoki Ohuchida; Norihiro Sato; Hiroki Toma; Hiroshi Yamaguchi; Makoto Hashizume; Cui Lin; Kazuhiro Mizumoto; Eishi Nagai; Masafumi Nakamura; Takao Ohtsuka; Masao Tanaka
MicroRNA-10a is overexpressed in human pancreatic cancer and involved in its invasiveness partially via suppression of the HOXA1 gene.
Ritsuko Yanaru-Fujisawa; Motohiro Esaki; Masaki Gushima; Minako Hirahashi; Takayuki Matsumoto; Tomohiko Moriyama; Eishi Nagai; Shotaro Nakamura; Tadatoshi Tsuchigame; Takanari Kitazono
Familial fundic gland polyposis with gastric cancer.

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All Publications

2013: Eishi Nagai; Kohei Nakata; Kenoki Ohuchida; Shuji Shimizu; Ryo Maeyama; Yoshihiro Miyasaka; Hiroki Toma; Masao Tanaka
Feasibility and safety of intracorporeal esophagojejunostomy after laparoscopic total gastrectomy: Inverted T-shaped anastomosis using linear staplers.
Surgery 2013;153(5):732-8.
2012: Kenoki Ohuchida; Norihiro Sato; Hiroki Toma; Hiroshi Yamaguchi; Makoto Hashizume; Cui Lin; Kazuhiro Mizumoto; Eishi Nagai; Masafumi Nakamura; Takao Ohtsuka; Masao Tanaka
MicroRNA-10a is overexpressed in human pancreatic cancer and involved in its invasiveness partially via suppression of the HOXA1 gene.
Annals of surgical oncology 2012;19(7):2394-402.
2012: Ritsuko Yanaru-Fujisawa; Motohiro Esaki; Masaki Gushima; Minako Hirahashi; Takayuki Matsumoto; Tomohiko Moriyama; Eishi Nagai; Shotaro Nakamura; Tadatoshi Tsuchigame; Takanari Kitazono
Familial fundic gland polyposis with gastric cancer.
Gut 2012;61(7):1103-4.
2011: Yoshihiro Miyasaka; Kazuhiro Mizumoto; Eishi Nagai; Kohei Nakata; Kenoki Ohuchida; Hayato Fujita; Akifumi Hayashi; Masazumi Tsuneyoshi; Masao Tanaka
Senescence in intraductal papillary mucinous neoplasm of the pancreas.
Human pathology 2011;42(12):2010-7.
2011: Kohei Nakata; Yoshinao Oda; Kenoki Ohuchida; Takao Otsuka; Hiroshi Sakai; Shinichi Aishima; Hayato Fujita; Naoki Ikenaga; Tadashi Kayashima; Cui Lin; Kazuhiro Mizumoto; Eishi Nagai; Masao Tanaka
MicroRNA-10b is overexpressed in pancreatic cancer, promotes its invasiveness, and correlates with a poor prognosis.
Surgery 2011;150(5):916-22.
2011: Takao Ohtsuka; Kenoki Ohuchida; Shuji Shimizu; Hideki Takanami; Daiki Eguchi; Eishi Nagai; Seiichi Odate; Hiroki Toma; Takashi Ueki; Masao Tanaka
Single-incision laparoscopy-assisted surgery for bowel obstruction: report of three cases.
Surgery today 2011;41(11):1519-23.
2011: Hiroshi Sakai; Hiroki Toma; Lin Cui; Kazuhiro Mizumoto; Eishi Nagai; Kohei Nakata; Kenoki Ohuchida; Masao Tanaka
Inhibition of p600 expression suppresses both invasiveness and anoikis resistance of gastric cancer.
Annals of surgical oncology 2011;18(7):2057-65.
2010: Akifumi Hayashi; Shinichi Aishima; Yoshihiro Miyasaka; Kohei Nakata; Katsuya Morimatsu; Yasunori Oda; Eishi Nagai; Yoshinao Oda; Masao Tanaka; Masazumi Tsuneyoshi
Pdcd4 expression in intraductal papillary mucinous neoplasm of the pancreas: its association with tumor progression and proliferation.
Human pathology 2010;41(11):1507-15.
2010: Manabu Onimaru; Kenoki Ohuchida; Eishi Nagai; Kazuhiro Mizumoto; Takuya Egami; Lin Cui; Norihiro Sato; Junji Uchino; Koichi Takayama; Makoto Hashizume; Masao Tanaka
Combination with low-dose gemcitabine and hTERT-promoter-dependent conditionally replicative adenovirus enhances cytotoxicity through their crosstalk mechanisms in pancreatic cancer.
Cancer letters 2010;294(2):178-86.
2010: Mitsuho Onimaru; Kenoki Ohuchida; T Egami; Kazuhiro Mizumoto; Eishi Nagai; L Cui; H Toma; Kunihiro Matsumoto; M Hashizume; Masao Tanaka
Gemcitabine synergistically enhances the effect of adenovirus gene therapy through activation of the CMV promoter in pancreatic cancer cells.
Cancer gene therapy 2010;17(8):541-9.
2010: Akifumi Hayashi; Shinichi Aishima; Takahiro Inoue; Kohei Nakata; Katsuya Morimatsu; Eishi Nagai; Yoshinao Oda; Masao Tanaka; Masazumi Tsuneyoshi
Decreased expression of focal adhesion kinase is associated with a poor prognosis in extrahepatic bile duct carcinoma.
Human pathology 2010;41(6):859-66.
2010: Kohei Nakata; Eishi Nagai; Kenoki Ohuchida; Akifumi Hayashi; Yoshihiro Miyasaka; Shinichi Aishima; Yoshinao Oda; Kazuhiro Mizumoto; Masao Tanaka; Masazumi Tsuneyoshi
S100P is a novel marker to identify intraductal papillary mucinous neoplasms.
Human pathology 2010;41(6):824-31.
2010: Manabu Onimaru; Kenoki Ohuchida; Kazuhiro Mizumoto; Eishi Nagai; Lin Cui; Hiroki Toma; Koichi Takayama; Kunio Matsumoto; Makoto Hashizume; Masao Tanaka
hTERT-promoter-dependent oncolytic adenovirus enhances the transduction and therapeutic efficacy of replication-defective adenovirus vectors in pancreatic cancer cells.
Cancer science 2010;101(3):735-42.
2010: Yoshihiro Miyasaka; Eishi Nagai; Kenoki Ohuchida; Kohei Nakata; Akifumi Hayashi; Kazuhiro Mizumoto; Masazumi Tsuneyoshi; Masao Tanaka
CD44v6 expression in intraductal papillary mucinous neoplasms of the pancreas.
Pancreas 2010;39(1):31-5.
2009: Naoki Ikenaga; Kenoki Ohuchida; Kazuhiro Mizumoto; Jun Yu; Hayato Fujita; Kohei Nakata; Junji Ueda; Norihiro Sato; Eishi Nagai; Masao Tanaka
S100A4 mRNA is a diagnostic and prognostic marker in pancreatic carcinoma.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2009;13(10):1852-8.
2009: Kohei Nakata; Kenoki Ohuchida; Eishi Nagai; Akifumi Hayashi; Yoshihiro Miyasaka; Tadashi Kayashima; Jun Yu; Shinichi Aishima; Yoshinao Oda; Kazuhiro Mizumoto; Masao Tanaka; Masazumi Tsuneyoshi
LMO2 is a novel predictive marker for a better prognosis in pancreatic cancer.
Neoplasia (New York, N.Y.) 2009;11(7):712-9.
2009: Taiki Moriyama; Kenoki Ohuchida; Kazuhiro Mizumoto; Jun Yu; Norihiro Sato; Toshinaga Nabae; Shunichi Takahata; Hiroki Toma; Eishi Nagai; Masao Tanaka
MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance.
Molecular cancer therapeutics 2009;8(5):1067-74.
2009: Kohei Nakata; Eishi Nagai; Kenoki Ohuchida; Shinichi Aishima; Akifumi Hayashi; Yoshihiro Miyasaka; Jun Yu; Kazuhiro Mizumoto; Masao Tanaka; Masazumi Tsuneyoshi
REG4 is associated with carcinogenesis in the 'intestinal' pathway of intraductal papillary mucinous neoplasms.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009;22(3):460-8.
2008: Noriko Tokunaga; Soichi Itaba; Shigetaka Yoshinaga; Hiroyuki Murao; Hirotada Akiho; Kazuhiko Nakamura; Eishi Nagai; Ayako Goto; Yumiko Segawa; Ryoichi Takayanagi
[A case of early recurrence with multiple liver metastases after curative operation of gastric cancer successfully treated by S-1/CDDP combination chemotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2008;35(11):1927-9.
2008: Seiji Ohhashi; Kenoki Ohuchida; Kazuhiro Mizumoto; Hayato Fujita; Takuya Egami; Jun Yu; Hiroki Toma; Shoko Sadatomi; Eishi Nagai; Masao Tanaka
Down-regulation of deoxycytidine kinase enhances acquired resistance to gemcitabine in pancreatic cancer.
Anticancer research 2008;28(4B):2205-12.
2008: Kosuke Yanai; Masafumi Nakamura; Takashi Akiyoshi; Shuntaro Nagai; Junji Wada; Kenichiro Koga; Hirokazu Noshiro; Eishi Nagai; Masazumi Tsuneyoshi; Masao Tanaka; Mitsuo Katano
Crosstalk of hedgehog and Wnt pathways in gastric cancer.
Cancer letters 2008;263(1):145-56.
2008: Takuya Egami; Kenoki Ohuchida; Kazuhiro Mizumoto; Mitsuho Onimaru; Hiroki Toma; Shoko Nishio; Eishi Nagai; Kunio Matsumoto; Toshikazu Nakamura; Masao Tanaka
Radiation enhances adenoviral gene therapy in pancreatic cancer via activation of cytomegalovirus promoter and increased adenovirus uptake.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(6):1859-67.
2007: Kenoki Ohuchida; Kazuhiro Mizumoto; Yoshihiro Miyasaka; J Yu; L Cui; Hiroshi Yamaguchi; H Toma; Shunichi Takahata; Norihiro Sato; Eishi Nagai; Koji Yamaguchi; Masazumi Tsuneyoshi; Masao Tanaka
Over-expression of S100A2 in pancreatic cancer correlates with progression and poor prognosis.
The Journal of pathology 2007;213(3):275-82.
2007: Yoshihiro Miyasaka; Eishi Nagai; Hiroshi Yamaguchi; Kei Fujii; Takahiro Inoue; Kenoki Ohuchida; Tomomi Yamada; Kazuhiro Mizumoto; Masao Tanaka; Masazumi Tsuneyoshi
The role of the DNA damage checkpoint pathway in intraductal papillary mucinous neoplasms of the pancreas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(15 Pt 1):4371-7.
2007: Kenoki Ohuchida; Kazuhiro Mizumoto; Seiji Ohhashi; Hiroshi Yamaguchi; Hiroyuki Konomi; Eishi Nagai; Koji Yamaguchi; Masazumi Tsuneyoshi; Masao Tanaka
Twist, a novel oncogene, is upregulated in pancreatic cancer: clinical implication of Twist expression in pancreatic juice.
International journal of cancer. Journal international du cancer 2007;120(8):1634-40.
2007: Kenoki Ohuchida; Kazuhiro Mizumoto; Jun Yu; Hiroshi Yamaguchi; Hiroyuki Konomi; Eishi Nagai; Koji Yamaguchi; Masazumi Tsuneyoshi; Masao Tanaka
S100A6 is increased in a stepwise manner during pancreatic carcinogenesis: clinical value of expression analysis in 98 pancreatic juice samples.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(4):649-54.
2007: Daisuke Yamada; Kenoki Ohuchida; Kazuhiro Mizumoto; Seiji Ohhashi; Jun Yu; Takuya Egami; Hayato Fujita; Eishi Nagai; Masao Tanaka
Increased expression of ADAM 9 and ADAM 15 mRNA in pancreatic cancer.
Anticancer research 2007;27(2):793-9.
2006: Kenoki Ohuchida; Kazuhiro Mizumoto; Seiji Ohhashi; Hiroshi Yamaguchi; Hiroyuki Konomi; Eishi Nagai; Koji Yamaguchi; Masazumi Tsuneyoshi; Masao Tanaka
S100A11, a putative tumor suppressor gene, is overexpressed in pancreatic carcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(18):5417-22.
2006: Kenoki Ohuchida; Kazuhiro Mizumoto; Takuya Egami; Hiroshi Yamaguchi; Kei Fujii; Hiroyuki Konomi; Eishi Nagai; Koji Yamaguchi; Masazumi Tsuneyoshi; Masao Tanaka
S100P is an early developmental marker of pancreatic carcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(18):5411-6.
2006: Kenoki Ohuchida; Kazuhiro Mizumoto; H Fujita; Hiroshi Yamaguchi; Hiroyuki Konomi; Eishi Nagai; Koji Yamaguchi; Masazumi Tsuneyoshi; Masao Tanaka
Sonic hedgehog is an early developmental marker of intraductal papillary mucinous neoplasms: clinical implications of mRNA levels in pancreatic juice.
The Journal of pathology 2006;210(1):42-8.
2006: Yasuhiro Ogura; Kazuhiro Mizumoto; Masao Tanaka; Kenoki Ohuchida; Mitsuhiko Murakami; Daisuke Yamada; Nami Ishikawa; Eishi Nagai
Strategy for prevention of local recurrence of pancreatic cancer after pancreatectomy: antitumor effect of gemcitabine mixed with fibrin glue in an orthotopic nude mouse model.
Surgery 2006;140(1):66-71.
2006: Jun Yu; Kenoki Ohuchida; Kazuhiro Mizumoto; Nami Ishikawa; Yasuhiro Ogura; Daisuke Yamada; Takuya Egami; Hayato Fujita; Seiji Ohashi; Eishi Nagai; Masao Tanaka
Overexpression of c-met in the early stage of pancreatic carcinogenesis; altered expression is not sufficient for progression from chronic pancreatitis to pancreatic cancer.
World journal of gastroenterology : WJG 2006;12(24):3878-82.
2006: Yasuhiro Ogura; Kazuhiro Mizumoto; Eishi Nagai; Mitsuhiko Murakami; Naoki Inadome; Michiyo Saimura; Kunihiro Matsumoto; Tetsuya Nakamura; Makoto Maemondo; Toshihiro Nukiwa; Masao Tanaka
Peritumoral injection of adenovirus vector expressing NK4 combined with gemcitabine treatment suppresses growth and metastasis of human pancreatic cancer cells implanted orthotopically in nude mice and prolongs survival.
Cancer gene therapy 2006;13(5):520-9.
2006: Kenoki Ohuchida; Kazuhiro Mizumoto; Daisuke Yamada; Hiroshi Yamaguchi; Hiroyuki Konomi; Eishi Nagai; Koji Yamaguchi; Masazumi Tsuneyoshi; Masao Tanaka
Quantitative analysis of human telomerase reverse transcriptase in pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 1):2066-9.
2006: Kenoki Ohuchida; Kazuhiro Mizumoto; Daisuke Yamada; Kei Fujii; Nami Ishikawa; Hiroyuki Konomi; Eishi Nagai; Koji Yamaguchi; Masazumi Tsuneyoshi; Masao Tanaka
Quantitative analysis of MUC1 and MUC5AC mRNA in pancreatic juice for preoperative diagnosis of pancreatic cancer.
International journal of cancer. Journal international du cancer 2006;118(2):405-11.
2006: Reiko Tanabe; Shuji Shimizu; Hiroyuki Konomi; Eishi Nagai; Koji Yamaguchi; Masao Tanaka
[Laparoscopic approach for gallbladder cancer].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 1():503-7.
2005: Kenoki Ohuchida; Kazuhiro Mizumoto; Nami Ishikawa; Kei Fujii; Hiroyuki Konomi; Eishi Nagai; Koji Yamaguchi; Masazumi Tsuneyoshi; Masao Tanaka
The role of S100A6 in pancreatic cancer development and its clinical implication as a diagnostic marker and therapeutic target.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7785-93.
2005: Mitsuhiko Murakami; Eishi Nagai; Kazuhiro Mizumoto; Michiyo Saimura; Kenoki Ohuchida; Naoki Inadome; Kunio Matsumoto; Toshikazu Nakamura; Makoto Maemondo; Toshihiro Nukiwa; Masao Tanaka
Suppression of metastasis of human pancreatic cancer to the liver by transportal injection of recombinant adenoviral NK4 in nude mice.
International journal of cancer. Journal international du cancer 2005;117(1):160-5.
2005: Koji Yamaguchi; Kenji Nakano; Eishi Nagai; Kazuo Chijiiwa; Moritoshi Kinoshita; Masayuki Ohta; Masao Tanaka
Ki-ras mutations in codon 12 and p53 mutations (biomarkers) and cytology in bile in patients with hepatobiliary-pancreatic carcinoma.
Hepato-gastroenterology 2005;52(63):713-8.
2005: Kenoki Ohuchida; Kazuhiro Mizumoto; Yasuhiro Ogura; Nami Ishikawa; Eishi Nagai; Koji Yamaguchi; Masao Tanaka
Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(6):2285-92.
2004: Tatsuya Manabe; Hidenobu Okino; Ryo Maeyama; Kazuhiro Mizumoto; Eishi Nagai; Masao Tanaka; Takehisa Matsuda
Novel strategic therapeutic approaches for prevention of local recurrence of pancreatic cancer after resection: trans-tissue, sustained local drug-delivery systems.
Journal of controlled release : official journal of the Controlled Release Society 2004;100(3):317-30.
2004: Shigeo Nakamura; Takayuki Matsumoto; Shotaro Nakamura; Kazuoki Hizawa; Mitsuo Iida; Takashi Yao; Eishi Nagai; Ryuichi Mibu
t(11; 18)(q21; q21)-associated low-grade mucosa-associated lymphoid tissue lymphoma involving the gastrointestinal tract, the lungs, and the salivary glands.
Journal of gastroenterology 2004;39(12):1220-2.
2004: Kenoki Ohuchida; Kazuhiro Mizumoto; Nami Ishikawa; Norihiro Sato; Eishi Nagai; Koji Yamaguchi; Hideki Takaishi; Toshinori Ide; Masao Tanaka
A highly sensitive and quantitative telomerase activity assay with pancreatic juice is useful for diagnosis of pancreatic carcinoma without problems due to polymerase chain reaction inhibitors: analysis of 100 samples of pancreatic juice from consecutive patients.
Cancer 2004;101(10):2309-17.
2004: Kenoki Ohuchida; Kazuhiro Mizumoto; Mitsuhiko Murakami; Li-Wu Qian; Norihiro Sato; Eishi Nagai; Kunio Matsumoto; Toshikazu Nakamura; Masao Tanaka
Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions.
Cancer research 2004;64(9):3215-22.
2003: Hirokazu Noshiro; Shuji Shimizu; Eishi Nagai; Kenoki Ohuchida; Masao Tanaka
Laparoscopy-assisted distal gastrectomy for early gastric cancer: is it beneficial for patients of heavier weight?
Annals of surgery 2003;238(5):680-5.
2003: Shuji Shimizu; Hirokazu Noshiro; Eishi Nagai; Akihiko Uchiyama; Masao Tanaka
Laparoscopic gastric surgery in a Japanese institution: analysis of the initial 100 procedures.
Journal of the American College of Surgeons 2003;197(3):372-8.
2003: Tatsuya Manabe; Kazuhiro Mizumoto; Eishi Nagai; Kunio Matsumoto; Toshikazu Nakamura; Toshihiro Nukiwa; Masao Tanaka; Takehisa Matsuda
Cell-based protein delivery system for the inhibition of the growth of pancreatic cancer: NK4 gene-transduced oral mucosal epithelial cell sheet.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):3158-66.
2003: Yukio Sonoda; Koji Yamaguchi; Eishi Nagai; Makoto Nakamuta; Tetsuhide Ito; Takashi Eguchi; Kazuo Chijiiwa; Masao Tanaka
Small cell carcinoma of the cystic duct: a case report.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2003;7(5):631-4.
2003: Takao Ohtsuka; Koji Yamaguchi; Jiro Ohuchida; Ken Inoue; Eishi Nagai; Kazuo Chijiiwa; Masao Tanaka
Comparison of quality of life after pylorus-preserving pancreatoduodenectomy and Whipple resection.
Hepato-gastroenterology 2003;50(51):846-50.
2003: Li-Wu Qian; Kazuhiro Mizumoto; Naoki Inadome; Eishi Nagai; Norihiro Sato; Kunio Matsumoto; Toshikazu Nakamura; Masao Tanaka
Radiation stimulates HGF receptor/c-Met expression that leads to amplifying cellular response to HGF stimulation via upregulated receptor tyrosine phosphorylation and MAP kinase activity in pancreatic cancer cells.
International journal of cancer. Journal international du cancer 2003;104(5):542-9.
2003: Li-Wu Qian; Kazuhiro Mizumoto; Naoki Maehara; Kenoki Ohuchida; Naoki Inadome; Michiyo Saimura; Eishi Nagai; Kunio Matsumoto; Toshikazu Nakamura; Masao Tanaka
Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: fibroblasts stimulate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production.
Cancer letters 2003;190(1):105-12.
2002: Takashi Yao; Miyuki Takata; Shuichi Tustsumi; Ken-ichi Nishiyama; Ken-ichi Taguchi; Eishi Nagai; Masazumi Tsuneyoshi
Phenotypic expression of gastrointestinal differentiation markers in colorectal adenocarcinomas with liver metastasis.
Pathology 2002;34(6):556-60.
2002: Michiyo Saimura; Eishi Nagai; Kazuhiro Mizumoto; Naoki Maehara; Yoji Andrew MINAMISHIMA; Mitsuo Katano; Kunio Matsumoto; Toshikazu Nakamura; Masao Tanaka
Tumor suppression through angiogenesis inhibition by SUIT-2 pancreatic cancer cells genetically engineered to secrete NK4.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(10):3243-9.
2002: Michiyo Saimura; Eishi Nagai; Kazuhiro Mizumoto; Naoki Maehara; Hidenobu Okino; Mitsuo Katano; Kunio Matsumoto; Toshikazu Nakamura; Kou Narumi; Toshihiro Nukiwa; Masao Tanaka
Intraperitoneal injection of adenovirus-mediated NK4 gene suppresses peritoneal dissemination of pancreatic cancer cell line AsPC-1 in nude mice.
Cancer gene therapy 2002;9(10):799-806.
2002: Li-Wu Qian; Kazuhiro Mizumoto; Taro Urashima; Eishi Nagai; Naoki Maehara; Norihiro Sato; Motowo Nakajima; Masao Tanaka
Radiation-induced increase in invasive potential of human pancreatic cancer cells and its blockade by a matrix metalloproteinase inhibitor, CGS27023.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(4):1223-7.
2002: Kazuhiro Mizumoto; Li-Wu Qian; Li Zhang; Eishi Nagai; Shinobu Kura; Masao Tanaka
A nitroimidazole derivative, PR-350, enhances the killing of pancreatic cancer cells exposed to high-dose irradiation under hypoxia.
Journal of radiation research 2002;43(1):43-51.
2002: Eishi Nagai; Masahiro Shinohara; Hirotoshi Yonemasu; Hideki Kishikawa; Masazumi Tsuneyoshi
Undifferentiated carcinoma of the common bile duct: case report and review of the literature.
Journal of hepato-biliary-pancreatic surgery 2002;9(5):627-31.
2002: Norihiro Sato; Kazuhiro Mizumoto; Eishi Nagai; Masao Tanaka
Telomerase as a new target for pancreatic cancer treatment.
Journal of hepato-biliary-pancreatic surgery 2002;9(3):322-7.
2002: Naoki Maehara; Eishi Nagai; Kazuhiro Mizumoto; Norihiro Sato; Kunio Matsumoto; Toshikazu Nakamura; Ko Narumi; Toshihiro Nukiwa; Masao Tanaka
Gene transduction of NK4, HGF antagonist, inhibits in vitro invasion and in vivo growth of human pancreatic cancer.
Clinical & experimental metastasis 2002;19(5):417-26.
2001: M Shono; Norihiro Sato; Kazuhiro Mizumoto; Yoji Andrew MINAMISHIMA; Minoru Nakamura; Naoki Maehara; Taro Urashima; Michiyo Saimura; L Qian; S Nishio; Eishi Nagai; Masao Tanaka
Effect of serum depletion on centrosome overduplication and death of human pancreatic cancer cells after exposure to radiation.
Cancer letters 2001;170(1):81-9.
2001: Koji Yamaguchi; M Kishinaka; Eishi Nagai; Kenji Nakano; Takao Ohtsuka; K Chijiwa; Masao Tanaka
Pancreatoduodenectomy for pancreatic head carcinoma with or without pylorus preservation.
Hepato-gastroenterology 2001;48(41):1479-85.
2001: K Furugaki; H Satoh; M Shinohara; Michiyo Saimura; Eishi Nagai; Hirotoshi Yonemasu; Hideki Kishikawa
Benign pseudotumorous lesion (fibroangiomyomatous hyperplasia with elastosis) in the gallbladder.
Journal of gastroenterology 2001;36(7):504-7.
2001: M Shono; Norihiro Sato; Kazuhiro Mizumoto; Naoki Maehara; Minoru Nakamura; Eishi Nagai; Masao Tanaka
Stepwise progression of centrosome defects associated with local tumor growth and metastatic process of human pancreatic carcinoma cells transplanted orthotopically into nude mice.
Laboratory investigation; a journal of technical methods and pathology 2001;81(7):945-52.
2001: H Niiyama; Kazuhiro Mizumoto; Norihiro Sato; Eishi Nagai; Ryuichi Mibu; T Fukui; M Kinoshita; Masao Tanaka
Quantitative analysis of hTERT mRNA expression in colorectal cancer.
The American journal of gastroenterology 2001;96(6):1895-900.
2001: Kazuo Chijiiwa; Kenji Nakano; Junji Ueda; Hirokazu Noshiro; Eishi Nagai; Koji Yamaguchi; Masao Tanaka
Surgical treatment of patients with T2 gallbladder carcinoma invading the subserosal layer.
Journal of the American College of Surgeons 2001;192(5):600-7.
2001: Norihiro Sato; Kazuhiro Mizumoto; Minoru Nakamura; Naoki Maehara; Yoji Andrew MINAMISHIMA; S Nishio; Eishi Nagai; Masao Tanaka
Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells.
Cancer genetics and cytogenetics 2001;126(1):13-9.
2001: I Mizumoto; Yoshiaki Ogawa; H Niiyama; Eishi Nagai; I Sato; T Urashima; Toshio Matsumoto; Mitsuo Iida; I Tanaka
Possible role of telomerase activation in the multistep tumor progression of periampullary lesions in patients with familial adenomatous polyposis.
The American journal of gastroenterology 2001;96(4):1261-5.
2001: N Sato; Kazuhiro Mizumoto; Naoki Maehara; M Shono; Eishi Nagai; Masao Tanaka
Instability of chromosome 8 as an indicator of aggressive tumor phenotype in pancreatic cancer.
Journal of surgical oncology 2001;76(3):181-7.
2001: Norihiro Sato; Naoki Maehara; Kazuhiro Mizumoto; Eishi Nagai; T Yasoshima; K Hirata; Masao Tanaka
Telomerase activity of cultured human pancreatic carcinoma cell lines correlates with their potential for migration and invasion.
Cancer 2001;91(3):496-504.
2000: M Takashima; T Ueki; Eishi Nagai; Takashi Yao; Koji Yamaguchi; Masao Tanaka; Masazumi Tsuneyoshi
Carcinoma of the ampulla of Vater associated with or without adenoma: a clinicopathologic analysis of 198 cases with reference to p53 and Ki-67 immunohistochemical expressions.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2000;13(12):1300-7.
2000: T Ogawa; M Kusumoto; Kazuhiro Mizumoto; Norihiro Sato; Eishi Nagai; A Ikubo; Y Aoki; Masao Tanaka
GM-CSF gene therapy using adenoviral vector in hamster pancreatic cancer.
Journal of hepato-biliary-pancreatic surgery 2000;7(3):306-11.
1999: T Kielian; Eishi Nagai; A Ikubo; CA Rasmussen; T Suzuki
Granulocyte/macrophage-colony-stimulating factor released by adenovirally transduced CT26 cells leads to the local expression of macrophage inflammatory protein 1alpha and accumulation of dendritic cells at vaccination sites in vivo.
Cancer immunology, immunotherapy : CII 1999;48(2-3):123-31.
1999: A Ikubo; Y Aoki; Eishi Nagai; T Suzuki
Highly metastatic variant of a mouse colon carcinoma cell line, LM17 and its response to GM-CSF gene therapy.
Clinical & experimental metastasis 1999;17(10):849-55.
1998: Eishi Nagai; T Ogawa; T Kielian; A Ikubo; T Suzuki
Irradiated tumor cells adenovirally engineered to secrete granulocyte/macrophage-colony-stimulating factor establish antitumor immunity and eliminate pre-existing tumors in syngeneic mice.
Cancer immunology, immunotherapy : CII 1998;47(2):72-80.
1998: K Furugaki; Eishi Nagai; M Shinohara; Michiyo Saimura; T Ueki; Satoshi Toyoshima; Hideki Kishikawa
Secretory carcinoma of the breast in an elderly woman: report of a case.
Surgery today 1998;28(2):219-22.