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Kojiro Nagai

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Hideharu Abe; Naoko Abe; Toshikazu Araoka; Seiji Kishi; Takeshi Matsubara; Taichi Murakami; Kojiro Nagai; Tatsuya Tominaga; Toshio Doi
Scleraxis modulates bone morphogenetic protein 4 (BMP4)-Smad1 protein-smooth muscle α-actin (SMA) signal transduction in diabetic nephropathy.
Seiji Kishi; Motokazu Matsuura; Akira Mima; Kojiro Nagai; Eriko Shibata; Satoshi Yamada; Hideharu Abe; Fumi Kishi; Toshio Doi
Acute glomerulonephritis in an immunocompetent elderly woman after contact with a child who had been diagnosed as erythema infectiosum.
Seiji Kishi; Takeshi Matsubara; Motokazu Matsuura; Akira Mima; Taichi Murakami; Kojiro Nagai; Tatsuya Tominaga; Otoya Ueda; Naoshi Fukushima; Noriyuki Iehara; Kou-ichi Jishage; Fumi Kishi; Hideharu Abe; Haruhiko Akiyama; Toshio Doi
SOX9 protein induces a chondrogenic phenotype of mesangial cells and contributes to advanced diabetic nephropathy.

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All Publications

2012: Hideharu Abe; Naoko Abe; Toshikazu Araoka; Seiji Kishi; Takeshi Matsubara; Taichi Murakami; Kojiro Nagai; Tatsuya Tominaga; Toshio Doi
Scleraxis modulates bone morphogenetic protein 4 (BMP4)-Smad1 protein-smooth muscle α-actin (SMA) signal transduction in diabetic nephropathy.
The Journal of biological chemistry 2012;287(24):20430-42.
2012: Seiji Kishi; Motokazu Matsuura; Akira Mima; Kojiro Nagai; Eriko Shibata; Satoshi Yamada; Hideharu Abe; Fumi Kishi; Toshio Doi
Acute glomerulonephritis in an immunocompetent elderly woman after contact with a child who had been diagnosed as erythema infectiosum.
Internal medicine (Tokyo, Japan) 2012;51(16):2197-201.
2011: Seiji Kishi; Takeshi Matsubara; Motokazu Matsuura; Akira Mima; Taichi Murakami; Kojiro Nagai; Tatsuya Tominaga; Otoya Ueda; Naoshi Fukushima; Noriyuki Iehara; Kou-ichi Jishage; Fumi Kishi; Hideharu Abe; Haruhiko Akiyama; Toshio Doi
SOX9 protein induces a chondrogenic phenotype of mesangial cells and contributes to advanced diabetic nephropathy.
The Journal of biological chemistry 2011;286(37):32162-9.
2011: Tatsuya Tominaga; Hideharu Abe; Otoya Ueda; Chisato Goto; Kunihiko Nakahara; Taichi Murakami; Takeshi Matsubara; Akira Mima; Kojiro Nagai; Toshikazu Araoka; Seiji Kishi; Naoshi Fukushima; Kou-ichi Jishage; Toshio Doi
Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy.
The Journal of biological chemistry 2011;286(22):20109-16.
2011: Akira Mima; Taichi Murakami; Kojiro Nagai; Reiko Shigeta; Fumihiko Shiota; Kazuhiro Yoshikawa; Hideharu Abe; Taro Akagi; Toshikazu Araoka; Toshio Doi; Noriyuki Iehara; Fumi Kishi; Seiji Kishi; Toru Kita; Naoki Kondo; Takeshi Matsubara; Motokazu Matsuura; Atsushi Fukatsu
An autopsy case of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) with intestinal bleeding in chronic renal failure.
Renal failure 2011;33(6):622-5.
2011: Taichi Murakami; Kojiro Nagai; Tsutomu Sakiyama; Hideharu Abe; Toshikazu Araoka; Yoshimi Bando; Fumi Kishi; Seiji Kishi; Naoki Kondo; Motokazu Matsuura; Akira Mima; Toshio Doi
MPO-ANCA-positive anti-glomerular basement membrane antibody disease successfully treated by plasma exchange and immunosuppressive therapy.
Renal failure 2011;33(6):626-31.
2011: Akira Mima; Hideharu Abe; Kojiro Nagai; Hidenori Arai; Takeshi Matsubara; Makoto Araki; Kazuo Torikoshi; Tatsuya Tominaga; Noriyuki Iehara; Atsushi Fukatsu; Toru Kita; Toshio Doi
Activation of Src mediates PDGF-induced Smad1 phosphorylation and contributes to the progression of glomerulosclerosis in glomerulonephritis.
PloS one 2011;6(3):e17929.
2008: Akira Mima; Hidenori Arai; Takeshi Matsubara; Hideharu Abe; Kojiro Nagai; Yukinori Tamura; Kazuo Torikoshi; Makoto Araki; Hiroshi Kanamori; Toshikazu Takahashi; Tatsuya Tominaga; Motokazu Matsuura; Noriyuki Iehara; Atsushi Fukatsu; Toru Kita; Toshio Doi
Urinary Smad1 is a novel marker to predict later onset of mesangial matrix expansion in diabetic nephropathy.
Diabetes 2008;57(6):1712-22.
2008: Hidenori Arai; Kojiro Nagai; Toshio Doi
Role of growth arrest-specific gene 6 in diabetic nephropathy.
Vitamins and hormones 2008;78():375-92.
2007: Hiroshi Kanamori; Takeshi Matsubara; Akira Mima; Eriko Sumi; Kojiro Nagai; Toshikazu Takahashi; Hideharu Abe; Noriyuki Iehara; Atsushi Fukatsu; Hiroshi Okamoto; Toru Kita; Toshio Doi; Hidenori Arai
Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephropathy.
Biochemical and biophysical research communications 2007;360(4):772-7.
2007: Akari Inada; Hidenori Arai; Kojiro Nagai; Jun-ichi Miyazaki; Yuichiro Yamada; Yutaka Seino; Atsushi Fukatsu
Gender difference in ICER Igamma transgenic diabetic mouse.
Bioscience, biotechnology, and biochemistry 2007;71(8):1920-6.
2007: Keiko Nomura; Ning Liu; Kojiro Nagai; Takamichi Hasegawa; Ikei Kobayashi; Fumiaki Nogaki; Misa Tanaka; Hidenori Arai; Atsushi Fukatsu; Toru Kita; Takahiko Ono
Roles of coagulation pathway and factor Xa in rat mesangioproliferative glomerulonephritis.
Laboratory investigation; a journal of technical methods and pathology 2007;87(2):150-60.
2006: Akira Mima; Takeshi Matsubara; Hidenori Arai; Hideharu Abe; Kojiro Nagai; Hiroshi Kanamori; Eriko Sumi; Toshikazu Takahashi; Noriyuki Iehara; Atsushi Fukatsu; Toru Kita; Toshio Doi
Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy.
Laboratory investigation; a journal of technical methods and pathology 2006;86(9):927-39.
2006: Takeshi Matsubara; Hideharu Abe; Hidenori Arai; Kojiro Nagai; Akira Mima; Hiroshi Kanamori; Eriko Sumi; Toshikazu Takahashi; Motokazu Matsuura; Noriyuki Iehara; Atsushi Fukatsu; Toru Kita; Toshio Doi
Expression of Smad1 is directly associated with mesangial matrix expansion in rat diabetic nephropathy.
Laboratory investigation; a journal of technical methods and pathology 2006;86(4):357-68.
2005: Akari Inada; Kojiro Nagai; Hidenori Arai; Jun-ichi Miyazaki; Keiko Nomura; Hiroshi Kanamori; Shinya Toyokuni; Yuichiro Yamada; Susan Bonner-Weir; Gordon C Weir; Atsushi Fukatsu; Yutaka Seino
Establishment of a diabetic mouse model with progressive diabetic nephropathy.
The American journal of pathology 2005;167(2):327-36.
2005: Kojiro Nagai; Takeshi Matsubara; Akira Mima; Eriko Sumi; Hiroshi Kanamori; Noriyuki Iehara; Atsushi Fukatsu; Motoko Yanagita; Toru Nakano; Yoshikazu Ishimoto; Toru Kita; Toshio Doi; Hidenori Arai
Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy.
Kidney international 2005;68(2):552-61.
2004: Hirokazu Ohashi; Hitoshi Takagi; Shinji Koyama; Hideyasu Oh; Daisuke Watanabe; David Antonetti; Takeshi Matsubara; Kojiro Nagai; Hidenori Arai; Toru Kita; Yoshihito Honda
Alterations in expression of angiopoietins and the Tie-2 receptor in the retina of streptozotocin induced diabetic rats.
Molecular vision 2004;10():608-17.
2003: Kojiro Nagai; Hidenori Arai; Motoko Yanagita; Takeshi Matsubara; Hiroshi Kanamori; Toru Nakano; Noriyuki Iehara; Atsushi Fukatsu; Toru Kita; Toshio Doi
Growth arrest-specific gene 6 is involved in glomerular hypertrophy in the early stage of diabetic nephropathy.
The Journal of biological chemistry 2003;278(20):18229-34.
2002: Motoko Yanagita; Yoshikazu Ishimoto; Hidenori Arai; Kojiro Nagai; Tsuyoshi Ito; Toru Nakano; David J Salant; Atsushi Fukatsu; Toshio Doi; Toru Kita
Essential role of Gas6 for glomerular injury in nephrotoxic nephritis.
The Journal of clinical investigation 2002;110(2):239-46.
2002: Masanobu Katayama; Taizo Wada; Kojiro Nagai; Hajime Takechi; Yoshio Wakatsuki; Toru Kita; Atsushi Fukatsu; Yoshihiro Yamada
[POEMS syndrome with increased vascular endothelial growth factor (VEGF) and multiple osteosclerotic lesion].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2002;91(6):1864-6.