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Ryozo Nagai

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Atsuko Nakayama; Hiroshi Ohtsu; Jiro Ando; Hideo Fujita; Hiroyuki Morita; Ryozo Nagai
Adverse cardiovascular outcomes associated with concurrent use of clopidogrel or ticlopidine and proton-pump inhibitors in patients undergoing percutaneous coronary intervention.
Jun-Ichi Okada; Teruyoshi Sasaki; Takumi Washio; Hiroshi Yamashita; Toshiaki Hisada; Yasushi Imai; Yoshimasa Kadooka; Taro Kariya; Ryozo Nagai; Machiko Nakagawa; Seiryo Sugiura
Patient specific simulation of body surface ECG using the finite element method.
Norihiko Ashigaki; Tomoya Hanatani; Yasunobu Hirata; Norio Aoyama; Yuichi Izumi; Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Asuka Sekinishi; Jun-Ichi Suzuki; Yuko Tada; Chisato Takamura; Kouji Wakayama; Ryo Watanabe; Hirofumi Zempo; Mitsuaki Isobe
Periodontal bacteria aggravate experimental autoimmune myocarditis in mice.

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2013: Atsuko Nakayama; Hiroshi Ohtsu; Jiro Ando; Hideo Fujita; Hiroyuki Morita; Ryozo Nagai
Adverse cardiovascular outcomes associated with concurrent use of clopidogrel or ticlopidine and proton-pump inhibitors in patients undergoing percutaneous coronary intervention.
Heart and vessels 2013;28(3):292-300.
2013: Jun-Ichi Okada; Teruyoshi Sasaki; Takumi Washio; Hiroshi Yamashita; Toshiaki Hisada; Yasushi Imai; Yoshimasa Kadooka; Taro Kariya; Ryozo Nagai; Machiko Nakagawa; Seiryo Sugiura
Patient specific simulation of body surface ECG using the finite element method.
Pacing and clinical electrophysiology : PACE 2013;36(3):309-21.
2013: Norihiko Ashigaki; Tomoya Hanatani; Yasunobu Hirata; Norio Aoyama; Yuichi Izumi; Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Asuka Sekinishi; Jun-Ichi Suzuki; Yuko Tada; Chisato Takamura; Kouji Wakayama; Ryo Watanabe; Hirofumi Zempo; Mitsuaki Isobe
Periodontal bacteria aggravate experimental autoimmune myocarditis in mice.
American journal of physiology. Heart and circulatory physiology 2013;304(5):H740-8.
2013: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Shun Minatsuki; Hironori Muraoka; Minoru Ono; Taro Shiga; Atsushi Yao; Masaru Hatano; Ryozo Nagai
Bosentan improved persistent pulmonary hypertension in a case after implantation of a left ventricular assist device.
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2013;16(1):101-4.
2013: Aiko Sakamoto; Minoru Yamakado; Yuko Ishizaka; Kazuhiko Koike; Ryozo Nagai; Nobukazu Ishizaka
Comparison of the impact of changes in waist circumference and body mass index in relation to changes in serum gamma-glutamyltransferase levels.
Journal of atherosclerosis and thrombosis 2013;20(2):142-51.
2013: Yumiko Yamamoto; Kenichi Ikeda; Hironobu Kikuchi; Toshihiro Morita; Toshiaki Nakajima; Fumitaka Nakamura; Gaku Oguri; Tomofumi Tanaka; Ryozo Nagai
Amiodarone inhibits tissue factor expression in monocytic THP-1 cells.
European journal of pharmacology 2013;701(1-3):14-9.
2013: Aiko Sakamoto; Mitsuhiro Fujishiro; Kazuhiko Koike; Ryozo Nagai; Nobukazu Ishizaka
The prevalence of malignant neoplastic and non-malignant gastrointestinal lesions in cardiology inpatients.
Journal of cardiology 2013;61(2):181-5.
2013: Yumiko Hosoya; Hironobu Hyodo; Eisuke Amiya; Jiro Ando; Tomoyuki Fujii; Akiko Hasegawa; Ryozo Nagai; Tomoko Nakao; Masahiro Terashima; Masafumi Watanabe; Issei Komuro
Cardiac magnetic resonance imaging in a patient with amniotic fluid embolism associated with severe cardiopulmonary complications.
International heart journal 2013;54(2):119-22.
2013: Atsuko Nakayama; Hiroaki Sugiyama; Masao Takahashi; Jiro Ando; Katsuhito Fujiu; Kazuyoshi Hina; Yasunobu Hirata; Yasushi Imai; Toshiya Kojima; Ryozo Nagai
Radiofrequency catheter ablation of the accessory pathway adversely affected the left ventricular outflow tract pressure gradient in a patient with hypertrophic obstructive cardiomyopathy.
International heart journal 2013;54(2):111-4.
2013: Kohro Takahide; Issei Komuro; Kazuhiko Ohe; Hiroki Sato; Tsutomu Yamazaki; Kenji Harada; Ryozo Nagai
Trends in antidiabetic prescription patterns in Japan from 2005 to 2011.
International heart journal 2013;54(2):93-7.
2013: Tatsuya Asanuma; Yasutomi Higashikuni; Toshiaki Hisada; Ryozo Nagai; Hiroshi Yamashita; Seiryo Sugiura
Discordance of the areas of peak wall shear stress and tissue stress in coronary artery plaques as revealed by fluid-structure interaction finite element analysis: a case study.
International heart journal 2013;54(1):54-8.
2013: Naomi Ogawa; Shinichi Takamoto; Norifumi Takeda; Tsuyoshi Taketani; Yasushi Imai; Masayoshi Kato; Tetsuro Morota; Ryozo Nagai; Kan Nawata; Hiroshi Nishimura; Yasunobu Hirata
Circulating transforming growth factor β-1 level in Japanese patients with Marfan syndrome.
International heart journal 2013;54(1):23-6.
2013: Naoko Kato; Koichiro Kinugawa; Issei Komuro; Hisataka Maki; Shun Minatsuki; Hironori Muraoka; Masaru Hatano; Teruhiko Imamura; Toshiro Inaba; Taro Shiga; Atsushi Yao; Ryozo Nagai
Trend of clinical outcome and surrogate markers during titration of β-blocker in heart failure patients with reduced ejection fraction: relevance of achieved heart rate and β-blocker dose.
Circulation journal : official journal of the Japanese Circulation Society 2013;77(4):1001-8.
2013: Shogo Watanabe; Eisuke Amiya; Yumiko Hosoya; Shuichi Kawarasaki; Issei Komuro; Koji Maemura; Tomoko Nakao; Kazuko Omori; Atsuko Ozeki; Munenori Takata; Aya Watanabe; Masafumi Watanabe; Ryozo Nagai
Simultaneous heart rate variability monitoring enhances the predictive value of flow-mediated dilation in ischemic heart disease.
Circulation journal : official journal of the Japanese Circulation Society 2013;77(4):1018-25.
2013: Toru Suzuki; Daigo Sawaki; Eduardo Bossone; Kim A Eagle; Raimund Erbel; Rolf Alexander Jánosi; Ryozo Nagai
Biomarkers of aortic diseases.
American heart journal 2013;165(1):15-25.
2013: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Shun Minatsuki; Hironori Muraoka; Taro Shiga; Atsushi Yao; Masaru Hatano; Ryozo Nagai
Novel criteria of urine osmolality effectively predict response to tolvaptan in decompensated heart failure patients--association between non-responders and chronic kidney disease.
Circulation journal : official journal of the Japanese Circulation Society 2013;77(2):397-404.
2012: Tetsu Tanaka; Yasunobu Hirata; Akiko Itai; Ryozo Nagai; Masahito Ogawa; Asuka Sekinishi; Jun-Ichi Suzuki; Mitsuaki Isobe
Inhibition of IκB phosphorylation prevents load-induced cardiac dysfunction in mice.
American journal of physiology. Heart and circulatory physiology 2012;303(12):H1435-45.
2012: Masahito Ogawa; Takaaki Senbonmatsu; Jun-Ichi Suzuki; Kiyoshi Takayama; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
Impaired post-infarction cardiac remodeling in chronic kidney disease is due to excessive renin release.
Laboratory investigation; a journal of technical methods and pathology 2012;92(12):1766-76.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Masaaki Akahane; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Ryozo Nagai
How to demonstrate the reversibility of end-organ function before implantation of left ventricular assist device in INTERMACS profile 2 patients?
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2012;15(4):395-8.
2012: Jun-Ichi Suzuki; Kiyoshi Takayama; Ryo Watanabe; Yasunobu Hirata; Keiichi Hishikari; Ryozo Nagai; Masahito Ogawa; Mitsuaki Isobe
Novel effects of macrolide antibiotics on cardiovascular diseases.
Cardiovascular therapeutics 2012;30(6):301-7.
2012: Taira Fukuda; Yasunobu Hirata; Haruko Iida; Kenichi Ikeda; Masayoshi Kato; Miwa Kurano; Koji Maemura; Nobuhito Masuda; Koshiro Monzen; Ryozo Nagai; Mika Nagasaki; Taro Shiga; Haruhito Takano; Tomofumi Tanaka; Kansei Uno; Yumiko Yamamoto; Hiroshi Yamashita; Toshiaki Nakajima
Cardiac rehabilitation decreases plasma pentraxin 3 in patients with cardiovascular diseases.
European journal of preventive cardiology 2012;19(6):1393-400.
2012: Takeya Minami; Ryozo Nagai; Yasuaki Nakagawa; Hiroyasu Nakano; Kazuhiro Nakao; Yutaka Kawahito; Akinori Kimura; Hideyuki Kinoshita; Yoshihiro Kuwabara; Koichiro Kuwahara; Toshio Nishikimi; Masataka Sata; Takahiro Seno; Junko Shibata; Kenji Sobue; Minoru Takaoka; Kenji Ueshima; Satoru Usami; Chinatsu Yamada; Yuko Yamada; Shinji Yasuno; Kazuwa Nakao
Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice.
The EMBO journal 2012;31(23):4428-40.
2012: Junichi Ishida; Ryozo Nagai
[Research on target therapy in cardiovascular diseases].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 8():378-82.
2012: Tomoko Nakao; Shuichiro Takanashi; Norihiko Takeda; Hiroyuki Watanabe; Ryozo Nagai
The efficacy of real-time three-dimensional transoesophageal echocardiography in detecting unicuspid aortic valve.
European heart journal cardiovascular Imaging 2012;13(11):966.
2012: Kentaro Yuda; Hiroyuki Aburatani; Tatsuya Inoue; Aya Iriyama; Kazuaki Kadonosono; Ryozo Nagai; Hidenori Takahashi; Yasuhiro Tamaki; Takashi Ueta; Yasuo Yanagi
Adrenomedullin inhibits choroidal neovascularization via CCL2 in the retinal pigment epithelium.
The American journal of pathology 2012;181(4):1464-72.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Ryozo Nagai
An elevated ratio of early to late diastolic filling velocity recovers after heart transplantation in a time-dependent manner.
Journal of cardiology 2012;60(4):295-300.
2012: Hajime Abe; Syuichiro Takanashi; Morimasa Takayama; Norihiko Takeda; Ryozo Nagai
Successful surgical repair of a giant coronary-pulmonary artery fistula: role of magnetic resonance imaging.
European heart journal cardiovascular Imaging 2012;13(10):826.
2012: Teruhiko Imamura; Toshiro Inaba; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Yasushi Imai; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Ryozo Nagai
Early decision for a left ventricular assist device implantation is necessary for patients with modifier A.
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2012;15(3):301-4.
2012: Jun-Ichi Suzuki; Yasunobu Hirata; Ryozo Nagai; Masahito Ogawa; Mitsuaki Isobe
Effects of immunoglobulin to prevent coronary allograft vasculopathy in heart transplantation.
Expert opinion on therapeutic targets 2012;16(8):783-9.
2012: Takehiro Takahashi; Zenshiro Tamaki; Takashi Taniguchi; Tetsuo Toyama; Aya Watanabe; Masafumi Watanabe; Eisuke Amiya; Yoshihide Asano; Masaru Hatano; Yasunobu Hirata; Yohei Ichimura; Shuichi Kawarasaki; Ryozo Nagai; Tomoko Nakao; Atsuko Ozeki; Shinichi Sato
Improvement of endothelial function in parallel with the amelioration of dry cough and dyspnea due to interstitial pneumonia by intravenous cyclophosphamide pulse therapy in patients with systemic sclerosis: a preliminary report of two cases.
Modern rheumatology / the Japan Rheumatism Association 2012;22(4):598-601.
2012: Naoko Kato; Keiko Kazuma; Koichiro Kinugawa; Taro Shiga; Norihiko Takeda; Masafumi Watanabe; Atsushi Yao; Masaru Hatano; Yasunobu Hirata; Yasushi Imai; Ryozo Nagai
Depressive symptoms are common and associated with adverse clinical outcomes in heart failure with reduced and preserved ejection fraction.
Journal of cardiology 2012;60(1):23-30.
2012: Teruhiko Imamura; Toshiro Inaba; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Ryozo Nagai
A case of late-onset right ventricular failure after implantation of a continuous-flow left ventricular assist device.
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2012;15(2):200-3.
2012: Atsuko Nakayama; Hiroshi Ohtsu; Tetsuya Sumiyoshi; Shuichiro Takanashi; Takafumi Akai; Jiro Ando; Hideo Fujita; Katsuyuki Hoshina; Tetsuro Miyata; Hiroyuki Morita; Masatoshi Nagayama; Ryozo Nagai
Inverse association between the existence of coronary artery disease and progression of abdominal aortic aneurysm.
Atherosclerosis 2012;222(1):278-83.
2012: Kosei Eguchi; Takashi Kadowaki; Masao Kimoto; Nozomu Kono; Ichiro Manabe; Kensuke Miyake; Fusa Ogata; Miho Ohsugi; Umeharu Ohto; Yumiko Oishi-Tanaka; Kazuyuki Tobe; Nobuhiro Yagi; Hiroyuki Arai; Ryozo Nagai
Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation.
Cell metabolism 2012;15(4):518-33.
2012: Aiko Sakamoto; Yasushi Imai; Nobukazu Ishizaka; Ryozo Nagai
Serum levels of IgG4 and soluble interleukin-2 receptor in patients with abdominal and thoracic aortic aneurysm who undergo coronary angiography.
Atherosclerosis 2012;221(2):602-3.
2012: Koichi Kimura; Hiroyuki Morita; Jiro Ando; Aya Ebihara; Hideo Fujita; Nobuaki Fukuda; Tomoko Okano; Katsu Takenaka; Kansei Uno; Yutaka Yatomi; Ryozo Nagai
Speckle tracking global strain rate E/E' predicts LV filling pressure more accurately than traditional tissue Doppler E/E'.
Echocardiography (Mount Kisco, N.Y.) 2012;29(4):404-10.
2012: Aiko Sakamoto; Kan Saito; Yasushi Imai; Nobukazu Ishizaka; Takahide Kohro; Kazuhiko Koike; Hiroyuki Morita; Ryozo Nagai
Serum levels of IgG4 and soluble interleukin-2 receptor in patients with coronary artery disease.
Clinica chimica acta; international journal of clinical chemistry 2012;413(5-6):577-81.
2012: Masahiro Myojo; Hiroki Sato; Daigo Sawaki; Masao Takahashi; Jiro Ando; Hideo Fujita; Yasunobu Hirata; Hiroshi Iwata; Arihiro Kiyosue; Kohro Takahide; Ryozo Nagai
Prognostic implication of macrocytosis on adverse outcomes after coronary intervention.
Atherosclerosis 2012;221(1):148-53.
2012: Aiko Sakamoto; Masao Takahashi; Norifumi Takeda; Hideomi Yamada; Kazuhiko Koike; Haruki Kume; Daichi Maeda; Ryozo Nagai; Kan Saito; Yutaka Enomoto; Masashi Fukayama; Kenji Hirano; Yasunobu Hirata; Yukio Homma; Yumiko Hosoya; Yasushi Imai; Nobukazu Ishizaka
Idiopathic retroperitoneal fibrosis, inflammatory aortic aneurysm, and inflammatory pericarditis--retrospective analysis of 11 case histories.
Journal of cardiology 2012;59(2):139-46.
2012: Yumiko Yoshiki; Masashi Fukayama; Junichi Ishida; Ryozo Nagai; Yasuhito Nannya; Yutaka Takazawa; Go Yamamoto; Mineo Kurokawa
AL amyloidosis with severe gastrointestinal invasion and acute obstructive suppurative cholangitis.
Annals of hematology 2012;91(3):467-8.
2012: Takeki Suzuki; Tsutomu Yamazaki; Doubun Hayashi; Takahide Kohro; Ryozo Nagai
Frequency and impact of lifestyle modification in patients with coronary artery disease: the Japanese Coronary Artery Disease (JCAD) study.
American heart journal 2012;163(2):268-73.
2012: Zenshiro Tamaki; Manabu Tomita; Atsushi Yao; Yoshihide Asano; Masaru Hatano; Tomohiko Kawashima; Koichiro Kinugawa; Ryozo Nagai; Shinichi Sato
Efficacy of low-dose imatinib mesylate for cutaneous involvement in systemic sclerosis: a preliminary report of three cases.
Modern rheumatology / the Japan Rheumatism Association 2012;22(1):94-9.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Ryozo Nagai
Correction of hyponatremia by tolvaptan before left ventricular assist device implantation.
International heart journal 2012;53(6):391-3.
2012: Junichi Ishida; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Masaru Hatano; Yasunobu Hirata; Teruhiko Imamura; Toshiro Inaba; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Ryozo Nagai
Rapidly progressive cardiac allograft vasculopathy in early onset regressed with everolimus treatment in an adult cardiac recipient.
International heart journal 2012;53(6):388-90.
2012: Asuka Sekinishi; Jun-Ichi Suzuki; Ryo Watanabe; Norio Aoyama; Norihiko Ashigaki; Tomoya Hanatani; Yasunobu Hirata; Yuichi Izumi; Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Mitsuaki Isobe
Periodontal pathogen Aggregatibacter actinomycetemcomitans deteriorates pressure overload-induced myocardial hypertrophy in mice.
International heart journal 2012;53(5):324-30.
2012: Junichi Ishida; Daigo Sawaki; Toru Suzuki; Kenichi Aizawa; Ryozo Nagai
Comparison of analytical performance of two single-step measurement devices of B-type natriuretic Peptide.
International heart journal 2012;53(5):320-3.
2012: Taira Fukuda; Yasunobu Hirata; Haruko Iida; Miwa Kurano; Akihiro Matsumoto; Toshihiro Morita; Ryozo Nagai; Haruhito Takano; Hiroshi Yamashita; Toshiaki Nakajima
Cardiac output response to exercise in chronic cardiac failure patients.
International heart journal 2012;53(5):293-8.
2012: Toshiro Inaba; Koichiro Kinugawa; Hisataka Maki; Masaru Hatano; Yasunobu Hirata; Teruhiko Imamura; Tomoko Nakao; Taro Shiga; Takahiro Shiota; Makoto Sonoda; Junichi Suzuki; Katsu Takenaka; Tadashi Yamazaki; Atsushi Yao; Ryozo Nagai
Volumetric and functional assessment of ventricles in pulmonary hypertension on 3-dimensional echocardiography.
Circulation journal : official journal of the Japanese Circulation Society 2012;77(1):198-206.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Ryozo Nagai
Preoperative levels of bilirubin or creatinine adjusted by age can predict their reversibility after implantation of left ventricular assist device.
Circulation journal : official journal of the Japanese Circulation Society 2012;77(1):96-104.
2012: Tomoya Hanatani; Yasunobu Hirata; Norio Aoyama; Yuichi Izumi; Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Jun-Ichi Suzuki; Mitsuaki Isobe
The periodontal pathogen Aggregatibacter actinomycetemcomitans deteriorates ventricular remodeling after myocardial infarction in mice.
International heart journal 2012;53(4):253-6.
2012: Hiroaki Semba; Katsura Soma; Norihiko Takeda; Tokuhisa Uejima; Takeshi Yamashita; Hajime Abe; Hitoshi Sawada; Ryozo Nagai
Basic echocardiographic features of patients with latent left ventricular outflow tract obstruction without left ventricular hypertrophy.
International heart journal 2012;53(4):230-3.
2012: Taro Shiga; Atsushi Yao; Takashi Nishimura; Minoru Ono; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Ryozo Nagai
Combination evaluation of preoperative risk indices predicts requirement of biventricular assist device.
Circulation journal : official journal of the Japanese Circulation Society 2012;76(12):2785-91.
2012: Katsura Soma; Masao Takahashi; Tomohiko Sato; Ryozo Nagai
Angina as a manifestation of constrictive pericarditis.
Internal medicine (Tokyo, Japan) 2012;51(14):1939.
2012: Kazuo Asada; Katsuhito Fujiu; Yasunobu Hirata; Yasushi Imai; Koichiro Kinugawa; Toshiya Kojima; Hiroaki Sugiyama; Takeki Suzuki; Ryozo Nagai
Intrathoracic impedance monitoring in patients with heart failure: correlation with dehydration and bleeding events.
Circulation journal : official journal of the Japanese Circulation Society 2012;76(11):2592-8.
2012: Teruhiko Imamura; Toshiro Inaba; Hiroyuki Isayama; Koichiro Kinugawa; Kazuhiko Koike; Hisataka Maki; Dai Mohri; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Taro Shiga; Atsushi Yao; Ryozo Nagai
A case of pancreatic cancer after heart transplantation.
International heart journal 2012;53(3):205-7.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Hisataka Maki; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Taro Shiga; Atsushi Yao; Ryozo Nagai
Successful conversion to everolimus after cytomegalovirus infection in a heart transplant recipient.
International heart journal 2012;53(3):199-201.
2012: Jun-Ichi Suzuki; Mitsuaki Isobe; Ryuichi Morishita; Ryozo Nagai
Applications of nucleic acid drugs for organ transplantation.
Current topics in medicinal chemistry 2012;12(15):1608-12.
2012: Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Jun-Ichi Suzuki; Norio Aoyama; Tomoya Hanatani; Yasunobu Hirata; Yuichi Izumi; Mitsuaki Isobe
Porphyromonas gingivalis accelerates neointimal formation after arterial injury.
Journal of vascular research 2012;49(5):417-24.
2012: Rikuta Hamaya; Yasunobu Hirata; Akiko Itai; Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Jun-Ichi Suzuki; Mitsuaki Isobe
A novel IKK inhibitor prevents progression of restenosis after arterial injury in mice.
International heart journal 2012;53(2):133-8.
2012: Hajime Abe; Hajime Aoki; Norihiko Takeda; Ryozo Nagai
Sinus of Valsalva aneurysm accompanying bicuspid aortic valve.
Internal medicine (Tokyo, Japan) 2012;51(10):1275.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Ryozo Nagai
Novel risk scoring system with preoperative objective parameters gives a good prediction of 1-year mortality in patients with a left ventricular assist device.
Circulation journal : official journal of the Japanese Circulation Society 2012;76(8):1895-903.
2012: Makoto Sahara; Masataka Sata; Yasunobu Hirata; Toshihiro Morita; Ryozo Nagai
Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension.
PloS one 2012;7(3):e33367.
2012: Katsura Soma; Yutaka Takazawa; Norihiko Takeda; Hiroshi Yamashita; Hajime Abe; Katsuhito Fujiu; Masashi Fukayama; Yasunobu Hirata; Toshiya Kojima; Hiroaki Semba; Yukako Shintani; Ryozo Nagai
Myocardial involvement in patients with osteogenesis imperfecta.
International heart journal 2012;53(1):75-7.
2012: Hiroaki Semba; Taro Shiga; Norihiko Takeda; Yumiko Terada; Yuichi Uchino; Akihiko Yonenaga; Hajime Abe; Eriko Hasumi; Yasunobu Hirata; Tsukasa Inajima; Hiroshi Iwata; Koichiro Kinugawa; Go Nishimura; Ryozo Nagai
Preliminary report of tolvaptan treatment in Japanese patients with heart failure.
International heart journal 2012;53(1):72-4.
2012: Jun-Ichi Suzuki; Yasunobu Hirata; Mitsuaki Isobe; Masahito Ogawa; Yoshiki Sakai; Ryozo Nagai
A prostacycline analog prevents chronic myocardial remodeling in murine cardiac allografts.
International heart journal 2012;53(1):64-7.
2012: Kohro Takahide; Masahiko Kurabayashi; Ichiro Manabe; Yoshihiro Morino; Hideo Fujita; Katsuhito Fujiu; Go Haraguchi; Yuji Ikari; Hiroshi Ikenouchi; Mitsuaki Isobe; Hiroshi Iwata; Atsushi Oguri; Kazuhiko Ohe; Ryozo Nagai
Development and implementation of an advanced coronary angiography and intervention database system.
International heart journal 2012;53(1):35-42.
2011: Naomi Ogawa; Yuji K Takahashi; Shinichi Takamoto; Norifumi Takeda; Tsuyoshi Taketani; Shoji Tsuji; Tsutomu Yamazaki; Jun Goto; Kazuo Hara; Yasushi Imai; Masayoshi Kato; Takahide Kohro; Hiroyuki Morita; Tetsuro Morota; Ryozo Nagai; Kan Nawata; Hiroshi Nishimura; Yasunobu Hirata
Evaluating Japanese patients with the Marfan syndrome using high-throughput microarray-based mutational analysis of fibrillin-1 gene.
The American journal of cardiology 2011;108(12):1801-7.
2011: Takeki Suzuki; Takeshi Yamashita; Tsutomu Yamazaki; Ryozo Nagai; Satoshi Ogawa
Echocardiographic predictors of frequency of paroxysmal atrial fibrillation (AF) and its progression to persistent AF in hypertensive patients with paroxysmal AF: results from the Japanese Rhythm Management Trial II for Atrial Fibrillation (J-RHYTHM II Study).
Heart rhythm : the official journal of the Heart Rhythm Society 2011;8(12):1831-6.
2011: Arihiro Kiyosue; Masahiro Myojo; Ryozo Nagai; Daisuke Nagata; Tomohiko Sato; Hiroshi Satonaka; Masao Takahashi; Yasunobu Hirata
Aldosterone-induced osteopontin gene transcription in vascular smooth muscle cells involves glucocorticoid response element.
Hypertension research : official journal of the Japanese Society of Hypertension 2011;34(12):1283-7.
2011: Koichi Kimura; Takahide Kohro; Hiroyuki Morita; Masataka Sata; Katsu Takenaka; Kansei Uno; Yutaka Yatomi; Aya Ebihara; Hiroshi Iwata; Ryozo Nagai
Reproducibility and diagnostic accuracy of three-layer speckle tracking echocardiography in a swine chronic ischemia model.
Echocardiography (Mount Kisco, N.Y.) 2011;28(10):1148-55.
2011: Jun-Ichi Suzuki; Ryo Watanabe; Yasunobu Hirata; Ryuichi Morishita; Ryozo Nagai; Masahito Ogawa; Mitsuaki Isobe
Autoimmune giant cell myocarditis: clinical characteristics, experimental models and future treatments.
Expert opinion on therapeutic targets 2011;15(10):1163-72.
2011: Ryozo Nagai
[108th Scientific Meeting of the Japanese Society of Internal Medicine: presidential lecture: medical research in elements and systems: from the standpoint of disease biology of the cardiovascular, metabolic and immune systems, and large-scale health record data systems].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(9):2383-401.
2011: Katsuhito Fujiu; Ichiro Manabe; Ryozo Nagai
Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice.
The Journal of clinical investigation 2011;121(9):3425-41.
2011: Takumi J Matsubara; Minoru Ono; Taro Shiga; Atsushi Yao; Masaru Hatano; Yasunobu Hirata; Hiroshi Iwata; Koichiro Kinugawa; Ryozo Nagai
Progressive coronary artery-pulmonary artery fistula after size-mismatch cardiac transplantation.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2011;57(4):346-7.
2011: Koichi Kimura; Katsu Takenaka; XiaoFang Pan; Aya Ebihara; Kansei Uno; Nobuaki Fukuda; Takahide Kohro; Hiroyuki Morita; Yutaka Yatomi; Ryozo Nagai
Prediction of coronary artery stenosis using strain imaging diastolic index at rest in patients with preserved ejection fraction.
Journal of cardiology 2011;57(3):311-5.
2011: Kensuke Tsushima; Tomoko Osawa; Hideyuki Yanai; Akira Nakajima; Akinori Takaoka; Ichiro Manabe; Yusuke Ohba; Yasushi Imai; Tadatsugu Taniguchi; Ryozo Nagai
IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(5):1531-43.
2011: Naoki Kobayashi; Kohjiro Ueki; Yukiko Okazaki; Aya Iwane; Naoto Kubota; Miho Ohsugi; Motoharu Awazawa; Masatoshi Kobayashi; Takayoshi Sasako; K Kaneko; Miho Suzuki; Yoshitaka Nishikawa; Kazuo Hara; Kotaro Yoshimura; Isao Koshima; Susumu Goyama; Koji Murakami; Junko Sasaki; Ryozo Nagai; Mineo Kurokawa; Takehiko Sasaki; Takashi Kadowaki
Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(14):5753-8.
2011: Kimie Tanaka; Daisuke Nagata; Yasunobu Hirata; Yasuhiko Tabata; Ryozo Nagai; Masataka Sata
Augmented angiogenesis in adventitia promotes growth of atherosclerotic plaque in apolipoprotein E-deficient mice.
Atherosclerosis 2011;215(2):366-73.
2011: Ryozo Nagai
[Overcoming intractable diseases. Preface].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(3):633-4.
2011: Jun-ichi Suzuki; Masahito Ogawa; Susumu Muto; Akiko Itai; Mitsuaki Isobe; Yasunobu Hirata; Ryozo Nagai
Novel IkB kinase inhibitors for treatment of nuclear factor-kB-related diseases.
Expert opinion on investigational drugs 2011;20(3):395-405.
2011: Jun-Ichi Suzuki; Masahito Ogawa; Susumu Muto; Akiko Itai; Yasunobu Hirata; Mitsuaki Isobe; Ryozo Nagai
Effects of specific chemical suppressors of plasminogen activator inhibitor-1 in cardiovascular diseases.
Expert opinion on investigational drugs 2011;20(2):255-64.
2011: Masahito Ogawa; Jun-ichi Suzuki; Yoichi Yamaguchi; Susumu Muto; Akiko Itai; Yasunobu Hirata; Mitsuaki Isobe; Ryozo Nagai
The effects of pharmacologic plasminogen activator inhibitor-1 inhibition in acute and chronic rejection in murine cardiac allografts.
Transplantation 2011;91(1):21-6.
2011: Tetsuya Saito; Masao Takahashi; Norihiko Takeda; Masafumi Watanabe; Hiroshi Yamashita; Kuni Ohtomo; Hideo Fujita; Yasunobu Hirata; Arihiro Kiyosue; Toshiya Kojima; Shuhei Komatsu; Koji Maemura; Takayoshi Matsumura; Ryozo Nagai
Successful blood sampling through azygos continuation with interrupted inferior vena cava. A case report and review of the literature.
International heart journal 2011;52(5):327-30.
2011: Hisataka Maki; Taro Shiga; Takeshi Yamashita; Atsushi Yao; Tadanori Aizawa; Masaru Hatano; Toshiro Inaba; Koichiro Kinugawa; Ryozo Nagai
Initial and programmed combination therapy with oral drugs for severe idiopathic pulmonary arterial hypertension.
International heart journal 2011;52(5):323-6.
2011: Jun-Ichi Suzuki; Kiyoshi Takayama; Ryo Watanabe; Yasunobu Hirata; Ryozo Nagai; Masahito Ogawa; Mitsuaki Isobe
Roles of prostaglandin E2 in cardiovascular diseases.
International heart journal 2011;52(5):266-9.
2011: Eriko Hasumi; Yasunobu Hirata; Yasushi Imai; Hiroshi Iwata; Jiro Ando; Hideo Fujita; Katsuhito Fujiu; Kan Saito; Ryozo Nagai
Diagnostic efficacy of coronary CT angiography as a follow-up modality for procedure-related coronary dissection.
International heart journal 2011;52(4):240-2.
2011: Masaru Hatano; Yasunobu Hirata; Koichiro Kinugawa; Atsushi Yao; Ryozo Nagai
Acute effect of sildenafil is maintained in pulmonary arterial hypertension patients chronically treated with bosentan.
International heart journal 2011;52(4):233-9.
2011: Kohro Takahide; Masahiko Kurabayashi; Katsumi Miyauchi; Ryozo Nagai; Taiki Tojo; Tsutomu Yamazaki; Hiroyuki Daida; Tohru Izumi
Intensively lowering both low-density lipoprotein cholesterol and blood pressure does not reduce cardiovascular risk in Japanese coronary artery disease patients.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(9):2062-70.
2011: Yumiko Oishi; Ichiro Manabe; Ryozo Nagai
[Krüppel-like family of transcription factor 5 (KLF5). KLF5 is a key regulator of adipocyte differentiation].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 1():264-8.
2011: Ryota Ochiai; Isao Shiraishi; Atsushi Yao; Koichiro Kinugawa; Ryozo Nagai; Koichiro Niwa
Status and future needs of regional adult congenital heart disease centers in Japan.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(9):2220-7.
2011: Tomofumi Tanaka; Yumiko Yamamoto; Tatsuya Yamasoba; Haruko Iida; Kenichi Ikeda; Hironobu Kikuchi; Toshihiro Morita; Ryozo Nagai; Toshiaki Nakajima
Effects of serum amyloid a and lysophosphatidylcholine on intracellular calcium concentration in human coronary artery smooth muscle cells.
International heart journal 2011;52(3):185-93.
2011: Takehiro Kamo; Takayoshi Matsumura; Yasunobu Hirata; Ryozo Nagai
Multiple pulmonary artery fistulas causing partial lung edema.
Internal medicine (Tokyo, Japan) 2011;50(11):1259-60.
2011: Naoko Kato; Keiko Kazuma; Koichiro Kinugawa; Masaru Hatano; Yasunobu Hirata; Satomi Seki; Taro Shiga; Atsushi Yao; Ryozo Nagai
Quality of life as an independent predictor for cardiac events and death in patients with heart failure.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(7):1661-9.
2011: Hideo Fujita; Ryozo Nagai
Glycemic control is another target of PCI in diabetic patients--to improve clinical outcome from outside the procedure.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(4):773-4.
2011: Masaru Hatano; Koichiro Kinugawa; Taro Shiga; Naoko Kato; Miyoko Endo; Motoyuki Hisagi; Takashi Nishimura; Atsushi Yao; Yasunobu Hirata; Shunei Kyo; Minoru Ono; Ryozo Nagai
Less frequent opening of the aortic valve and a continuous flow pump are risk factors for postoperative onset of aortic insufficiency in patients with a left ventricular assist device.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(5):1147-55.
2011: Dai Kawashima; Takayuki Ohno; Osamu Kinoshita; Noboru Motomura; Arihiro Kiyosue; Hideo Fujita; Jiro Ando; Kazuyoshi Ohtomo; Takashi Shigeeda; Satoshi Kato; Takashi Kadowaki; Ryozo Nagai; Shinichi Takamoto; Minoru Ono
Prevalence of vitreous hemorrhage following coronary revascularization in patients with diabetic retinopathy.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(2):329-35.
2011: Taro Shiga; Koichiro Kinugawa; Masaru Hatano; Atsushi Yao; Takashi Nishimura; Miyoko Endo; Naoko Kato; Yasunobu Hirata; Shunei Kyo; Minoru Ono; Ryozo Nagai
Age and preoperative total bilirubin level can stratify prognosis after extracorporeal pulsatile left ventricular assist device implantation.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(1):121-8.
2010: Aiko Sakamoto; Yuko Ishizaka; Ei-Ichi Toda; Ryozo Nagai; Kazuhiko Koike; Minoru Yamakado; Nobukazu Ishizaka
Impact of changes in obesity parameters on glucose metabolism and insulin resistance over a one-year period.
Journal of atherosclerosis and thrombosis 2010;17(12):1246-55.
2010: Naoya Takayama; Satoshi Nishimura; Sou Nakamura; Takafumi Shimizu; Ryoko Ohnishi; Hiroshi Endo; Tomoyuki Yamaguchi; Makoto Otsu; Ken Nishimura; Mahito Nakanishi; Akira Sawaguchi; Ryozo Nagai; Kazutoshi Takahashi; Shinya Yamanaka; Hiromitsu Nakauchi; Koji Eto
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells.
The Journal of experimental medicine 2010;207(13):2817-30.
2010: Daiju Fukuda; Soichiro Enomoto; Yoichiro Hirata; Ryozo Nagai; Masataka Sata
The angiotensin receptor blocker, telmisartan, reduces and stabilizes atherosclerosis in ApoE and AT1aR double deficient mice.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2010;64(10):712-7.
2010: Masatoshi Fujita; Shigetake Sasayama; Fumio Terasaki; Satoko Mitani; Tatsuya Morimoto; Tsutomu Yamazaki; Doubun Hayashi; Takahide Kohro; Yoshihiro Okada; Ryozo Nagai
Treatment effects of renin-angiotensin system inhibitor and calcium channel blocker in patients with coronary artery narrowing (from the Japanese Coronary Artery Disease Study).
Heart and vessels 2010;25(6):453-9.
2010: Arihiro Kiyosue; Yasunobu Hirata; Jiro Ando; Hideo Fujita; Toshihiro Morita; Masao Takahashi; Daisuke Nagata; Kohro Takahide; Yasushi Imai; Ryozo Nagai
Plasma cystatin C concentration reflects the severity of coronary artery disease in patients without chronic kidney disease.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(11):2441-7.
2010: Toshiaki Nakajima; Miwa Kurano; Takaaki Hasegawa; Haruhito Takano; Haruko Iida; Tomohiro Yasuda; Taira Fukuda; Haruhiko Madarame; Kansei Uno; Kentaro Meguro; Taro Shiga; Mina Sagara; Taiji Nagata; Koji Maemura; Yasunobu Hirata; Tatsuya Yamasoba; Ryozo Nagai
Pentraxin3 and high-sensitive C-reactive protein are independent inflammatory markers released during high-intensity exercise.
European journal of applied physiology 2010;110(5):905-13.
2010: K Kataoka; Yasuhito Nannya; H Iwata; S Seo; K Kumano; Tokiharu Takahashi; Ryozo Nagai; Mineo Kurokawa
Plasma brain natriuretic peptide is associated with hepatic veno-occlusive disease and early mortality after allogeneic hematopoietic stem cell transplantation.
Bone marrow transplantation 2010;45(11):1631-7.
2010: Jun-Ichi Suzuki; Norio Aoyama; Masahito Ogawa; Yasunobu Hirata; Yuichi Izumi; Ryozo Nagai; Mitsuaki Isobe
Periodontitis and cardiovascular diseases.
Expert opinion on therapeutic targets 2010;14(10):1023-7.
2010: Jun-Ichi Suzuki; Masahito Ogawa; Noriko Tamura; Yasuhiro Maejima; Kiyoshi Takayama; Koji Maemura; Kazuki Honda; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
A critical role of sympathetic nerve regulation for the treatment of impaired daily rhythm in hypertensive Dahl rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(10):1060-5.
2010: Takuya Nakajima; Keiichi Hishikari; Masahito Ogawa; Ryo Watanabe; Jun-Ichi Suzuki; Ayako Nagashima; Mayumi Masumura; Kiyoshi Takayama; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
Clarithromycin attenuates myocardial ischemia-reperfusion injury.
Expert opinion on therapeutic targets 2010;14(9):881-93.
2010: Nobukazu Ishizaka; Aiko Sakamoto; Kan Saito; Ryozo Nagai
The observation that risk increases according to the number of components does not necessarily indicate that each component is a risk factor.
Journal of atherosclerosis and thrombosis 2010;17(8):889-90.
2010: Hiroyuki Morita; Ryozo Nagai; J G Seidman; Christine E Seidman
Sarcomere gene mutations in hypertrophy and heart failure.
Journal of cardiovascular translational research 2010;3(4):297-303.
2010: Masaru Hatano; Atsushi Yao; Taro Shiga; Koichiro Kinugawa; Yasunobu Hirata; Ryozo Nagai
Imatinib mesylate has the potential to exert its efficacy by down-regulating the plasma concentration of platelet-derived growth factor in patients with pulmonary arterial hypertension.
International heart journal 2010;51(4):272-6.
2010: Makoto Sahara; Masataka Sata; Toshihiro Morita; Toshiaki Nakajima; Yasunobu Hirata; Ryozo Nagai
A phosphodiesterase-5 inhibitor vardenafil enhances angiogenesis through a protein kinase G-dependent hypoxia-inducible factor-1/vascular endothelial growth factor pathway.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(7):1315-24.
2010: Atsushi Oguri; Tomofumi Tanaka; Haruko Iida; Kentarou Meguro; Haruhito Takano; Hitoshi Oonuma; Satoshi Nishimura; Toshihiro Morita; Tatsuya Yamasoba; Ryozo Nagai; Toshiaki Nakajima
Involvement of CaV3.1 T-type calcium channels in cell proliferation in mouse preadipocytes.
American journal of physiology. Cell physiology 2010;298(6):C1414-23.
2010: Yumiko Oishi; Ichiro Manabe; Yasushi Imai; Kazuo Hara; Momoko Horikoshi; Katsuhito Fujiu; Toshihiro Tanaka; Tadanori Aizawa; Takashi Kadowaki; Ryozo Nagai
Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associated with human hypertension.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(6):1780-8.
2010: Taira Fukuda; Taketeru Maegawa; Akihiro Matsumoto; Yutaka Komatsu; Toshiaki Nakajima; Ryozo Nagai; Takashi Kawahara
Effects of acute hypoxia at moderate altitude on stroke volume and cardiac output during exercise.
International heart journal 2010;51(3):170-5.
2010: Hiroshi Iwata; Masataka Sata; Jiro Ando; Hideo Fujita; Toshihiro Morita; Daigo Sawaki; Masao Takahashi; Yoichiro Hirata; Shuichiro Takanashi; Minoru Tabata; Yasunobu Hirata; Ryozo Nagai
Impact of primitive cells in intracoronary thrombi on lesion prognosis: temporal analysis of cellular constituents of thrombotic material obtained from patients with acute coronary syndrome.
Heart (British Cardiac Society) 2010;96(10):748-55.
2010: Kohro Takahide; Doubun Hayashi; Tsutomu Yamazaki; Ryozo Nagai
Beta-blocker prescription among Japanese cardiologists and its effect on various outcomes.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(5):962-9.
2010: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Minoru Yamakado; Kazuhiko Koike; Ryozo Nagai
Association between gamma-glutamyltransferase levels and insulin resistance according to alcohol consumption and number of cigarettes smoked.
Journal of atherosclerosis and thrombosis 2010;17(5):476-85.
2010: Keiichi Hishikari; Ryo Watanabe; Masahito Ogawa; Jun-Ichi Suzuki; Mayumi Masumura; Tomoko Shimizu; Kiyoshi Takayama; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
Early treatment with clarithromycin attenuates rat autoimmune myocarditis via inhibition of matrix metalloproteinase activity.
Heart (British Cardiac Society) 2010;96(7):523-7.
2010: Arihiro Kiyosue; Yasunobu Hirata; Jiro Ando; Hideo Fujita; Toshihiro Morita; Masao Takahashi; Daisuke Nagata; Kohro Takahide; Yasushi Imai; Ryozo Nagai
Relationship between renal dysfunction and severity of coronary artery disease in Japanese patients.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(4):786-91.
2010: Jun-ichi Suzuki; Masahito Ogawa; Kiyoshi Takayama; Yoshiaki Taniyama; Ryuichi Morishita; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
Ultrasound-microbubble-mediated intercellular adhesion molecule-1 small interfering ribonucleic acid transfection attenuates neointimal formation after arterial injury in mice.
Journal of the American College of Cardiology 2010;55(9):904-13.
2010: Tsuyoshi Shimizu; Takayuki Ohno; Jiro Ando; Hideo Fujita; Ryozo Nagai; Noboru Motomura; Minoru Ono; Shunei Kyo; Shinichi Takamoto
Mid-term results and costs of coronary artery bypass vs drug-eluting stents for unprotected left main coronary artery disease.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(3):449-55.
2010: Nobukazu Ishizaka; Makiko Hongo; Gen Matsuzaki; Kyoko Furuta; Kan Saito; Ryota Sakurai; Aiko Sakamoto; Kazuhiko Koike; Ryozo Nagai
Effects of the AT(1) receptor blocker losartan and the calcium channel blocker benidipine on the accumulation of lipids in the kidney of a rat model of metabolic syndrome.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(3):263-8.
2010: Nobukazu Ishizaka; Yuko Ishizaka; Akiko Toda; Mizuki Tani; Kazuhiko Koike; Minoru Yamakado; Ryozo Nagai
Changes in waist circumference and body mass index in relation to changes in serum uric acid in Japanese individuals.
The Journal of rheumatology 2010;37(2):410-6.
2010: Jun-ichi Suzuki; Mitsuaki Isobe; Ryuichi Morishita; Ryozo Nagai
Characteristics of chronic rejection in heart transplantation: important elements of pathogenesis and future treatments.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(2):233-9.
2010: Masao Takahashi; Etsu Suzuki; Shigeyoshi Oba; Hiroaki Nishimatsu; Kenjiro Kimura; Tetsuo Nagano; Ryozo Nagai; Yasunobu Hirata
Adipose tissue-derived stem cells inhibit neointimal formation in a paracrine fashion in rat femoral artery.
American journal of physiology. Heart and circulatory physiology 2010;298(2):H415-23.
2010: Masaki Igarashi; Jun-ichi Osuga; Masashi Isshiki; Motohiro Sekiya; Hiroaki Okazaki; Satoru Takase; Mikio Takanashi; Keisuke Ohta; Masayoshi Kumagai; Makiko Nishi; Toshiro Fujita; Ryozo Nagai; Takashi Kadowaki; Shun Ishibashi
Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N-terminal sequence.
Journal of lipid research 2010;51(2):274-85.
2010: Yuichi Uchino; Masafumi Watanabe; Yasunobu Hirata; Kunihiro Shigematsu; Tetsuro Miyata; Ryozo Nagai
Efficacy of renal revascularization in a patient with fibromuscular renal artery stenosis and heart failure.
International heart journal 2010;51(6):432-5.
2010: Naomi Ogawa; Yasushi Imai; Hiroyuki Morita; Ryozo Nagai
Genome-wide association study of coronary artery disease.
International journal of hypertension 2010;2010():790539.
2010: Kohro Takahide; Masatoshi Fujita; Shigetake Sasayama; Satoko Mitani; Tsutomu Yamazaki; Dobun Hayashi; Yoshihiro Okada; Ryozo Nagai
Prognostic effects of combined treatment with calcium channel blockers and statins in patients with coronary narrowing: from the Japanese Coronary Artery Disease study.
International heart journal 2010;51(5):299-302.
2010: Yasunobu Hirata; Daisuke Nagata; Etsu Suzuki; Hiroaki Nishimatsu; Jun-Ichi Suzuki; Ryozo Nagai
Diagnosis and treatment of endothelial dysfunction in cardiovascular disease.
International heart journal 2010;51(1):1-6.
2010: Norifumi Takeda; Ichiro Manabe; Yuichi Uchino; Kosei Eguchi; Sahohime Matsumoto; Satoshi Nishimura; Takayuki Shindo; Motoaki Sano; Kinya Otsu; Paige Snider; Simon J Conway; Ryozo Nagai
Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload.
The Journal of clinical investigation 2010;120(1):254-65.
2010: Takayuki Ohno; Osamu Kinoshita; Hideo Fujita; Satoshi Kato; Akira Hirose; Takashi Sigeeda; Kazuyoshi Otomo; Jiro Ando; Takashi Kadowaki; Makoto Araie; Ryozo Nagai; Shinichi Takamoto
Detecting occult coronary artery disease followed by early coronary artery bypass surgery in patients with diabetic retinopathy: report from a diabetic retinocoronary clinic.
The Journal of thoracic and cardiovascular surgery 2010;139(1):92-7.
2009: Takayoshi Matsumura; Toru Suzuki; Kenichi Aizawa; Daigo Sawaki; Yoshiko Munemasa; Junichi Ishida; Ryozo Nagai
Regulation of transforming growth factor-beta-dependent cyclooxygenase-2 expression in fibroblasts.
The Journal of biological chemistry 2009;284(51):35861-71.
2009: Daiju Fukuda; Soichiro Enomoto; Ryozo Nagai; Masataka Sata
Inhibition of renin-angiotensin system attenuates periadventitial inflammation and reduces atherosclerotic lesion formation.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2009;63(10):754-61.
2009: Motohiro Sekiya; Naoya Yahagi; Yoshiaki Tamura; Hiroaki Okazaki; Masaki Igarashi; Keisuke Ohta; Mikio Takanashi; Masayoshi Kumagai; Satoru Takase; Makiko Nishi; Yoshinori Takeuchi; Yoshihiko Izumida; Midori Kubota; Ken Ohashi; Yoko Iizuka; Hiroaki Yagyu; Takanari Gotoda; Ryozo Nagai; Hitoshi Shimano; Nobuhiro Yamada; Takashi Kadowaki; Shun Ishibashi; Jun-ichi Osuga
Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.
Biochemical and biophysical research communications 2009;387(3):511-5.
2009: Motohiro Sekiya; Jun-ichi Osuga; Shuichi Nagashima; Taichi Ohshiro; Masaki Igarashi; Hiroaki Okazaki; Manabu Takahashi; Fumiko Tazoe; Taeko Wada; Keisuke Ohta; Mikio Takanashi; Masayoshi Kumagai; Makiko Nishi; Satoru Takase; Naoya Yahagi; Hiroaki Yagyu; Ken Ohashi; Ryozo Nagai; Takashi Kadowaki; Yusuke Furukawa; Shun Ishibashi
Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.
Cell metabolism 2009;10(3):219-28.
2009: Nobuhiro Yagi; Ichiro Manabe; Tsuneaki Tottori; Atsushi Ishihara; Fusa Ogata; Jong Heon Kim; Satoshi Nishimura; Katsuhito Fujiu; Yumiko Oishi; Keiji Itaka; Yasuki Kato; Masahiro Yamauchi; Ryozo Nagai
A nanoparticle system specifically designed to deliver short interfering RNA inhibits tumor growth in vivo.
Cancer research 2009;69(16):6531-8.
2009: Satoshi Nishimura; Ichiro Manabe; Ryozo Nagai
Adipose tissue inflammation in obesity and metabolic syndrome.
Discovery medicine 2009;8(41):55-60.
2009: Satoshi Nishimura; Ichiro Manabe; Mika Nagasaki; Koji Eto; Hiroshi Yamashita; Miho Ohsugi; Makoto Otsu; Kazuo Hara; Kohjiro Ueki; Seiryo Sugiura; Kotaro Yoshimura; Takashi Kadowaki; Ryozo Nagai
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity.
Nature medicine 2009;15(8):914-20.
2009: Hiroshi Iwata; Kazuto Nakamura; Makoto Sumi; Mikio Ninomiya; Yoshiki Sakai; Yoichiro Hirata; Masahi Akaike; Takashi Igarashi; Shinichi Takamoto; Ryozo Nagai; Masataka Sata
Local delivery of synthetic prostacycline agonist augments collateral growth and improves cardiac function in a swine chronic cardiac ischemia model.
Life sciences 2009;85(5-6):255-61.
2009: Masahito Ogawa; Jun-ichi Suzuki; Hisanori Kosuge; Kiyoshi Takayama; Ryozo Nagai; Mitsuaki Isobe
The mechanism of anti-inflammatory effects of prostaglandin E2 receptor 4 activation in murine cardiac transplantation.
Transplantation 2009;87(11):1645-53.
2009: Daiju Fukuda; Soichiro Enomoto; Ibuki Shirakawa; Ryozo Nagai; Masataka Sata
Fluvastatin accelerates re-endothelialization impaired by local sirolimus treatment.
European journal of pharmacology 2009;612(1-3):87-92.
2009: Hiroyuki Morita; Ryozo Nagai
[Genomic research in hypertension and cardiovascular diseases].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(6):1095-102.
2009: Nobukazu Ishizaka; Yuko Ishizaka; Minoru Yamakado; Ei-Ichi Toda; Kazuhiko Koike; Ryozo Nagai
Association between metabolic syndrome and carotid atherosclerosis in individuals without diabetes based on the oral glucose tolerance test.
Atherosclerosis 2009;204(2):619-23.
2009: Masahito Ogawa; Jun-Ichi Suzuki; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
A critical role of COX-2 in the progression of neointimal formation after wire injury in mice.
Expert opinion on therapeutic targets 2009;13(5):505-11.
2009: Motoharu Awazawa; Kohjiro Ueki; Kazunori Inabe; Toshimasa Yamauchi; Kazuma Kaneko; Yukiko Okazaki; Nabeel Bardeesy; Shin Ohnishi; Ryozo Nagai; Takashi Kadowaki
Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway.
Biochemical and biophysical research communications 2009;382(1):51-6.
2009: Toru Suzuki; Daigo Sawaki; Kenichi Aizawa; Yoshiko Munemasa; Takayoshi Matsumura; Junichi Ishida; Ryozo Nagai
Kruppel-like factor 5 shows proliferation-specific roles in vascular remodeling, direct stimulation of cell growth, and inhibition of apoptosis.
The Journal of biological chemistry 2009;284(14):9549-57.
2009: Hiroyuki Atsuta; Tsuyoshi Uchiyama; Hiroyoshi Kanai; Tatsuya Iso; Toru Tanaka; Tatsuo Suga; Toshitaka Maeno; Masashi Arai; Ryozo Nagai; Masahiko Kurabayashi
Effects of a stable prostacyclin analogue beraprost sodium on VEGF and PAI-1 gene expression in vascular smooth muscle cells.
International journal of cardiology 2009;132(3):411-8.
2009: Kansei Uno; Katsu Takenaka; Aya Ebihara; Kan Nawata; Naoto Hayashi; Mika Nagasaki; Makoto Sonoda; Ohno Takayuki; Minoru Ono; Shunei Kyo; Ryozo Nagai; Shinichi Takamoto
Value of live 3D transoesophageal echocardiography in the diagnosis of mitral valve lesions.
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 2009;10(2):350-1.
2009: Makiko Hongo; Nobukazu Ishizaka; Kyoko Furuta; Naoya Yahagi; Kan Saito; Ryota Sakurai; Gen Matsuzaki; Kazuhiko Koike; Ryozo Nagai
Administration of angiotensin II, but not catecholamines, induces accumulation of lipids in the rat heart.
European journal of pharmacology 2009;604(1-3):87-92.
2009: Daisuke Nagata; Arihiro Kiyosue; Masao Takahashi; Hiroshi Satonaka; Kimie Tanaka; Masataka Sata; Tetsuo Nagano; Ryozo Nagai; Yasunobu Hirata
A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(2):133-9.
2009: Akihiro Masuzawa; Takayuki Ohno; Shinichi Takamoto; Noboru Motomura; Minoru Ono; Hideo Fujita; Jiro Ando; Toshihiro Morita; Yasunobu Hirata; Ryozo Nagai; Akira Hirose; Takashi Shigeeda; Satoshi Kato; Makoto Araie
In early-stage diabetic retinopathy, risk of cardiac events after implantation of sirolimus-eluting stent is higher than after coronary artery bypass surgery.
Journal of cardiology 2009;53(1):86-93.
2009: Taku Watanabe; Naoto Kubota; Miho Ohsugi; Tetsuya Kubota; Iseki Takamoto; Masato Iwabu; Motoharu Awazawa; Hisayuki Katsuyama; Chiaki Hasegawa; Kumpei Tokuyama; Masao Moroi; Kaoru Sugi; Toshimasa Yamauchi; Tetsuo Noda; Ryozo Nagai; Yasuo Terauchi; Kazuyuki Tobe; Kohjiro Ueki; Takashi Kadowaki
Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways.
The Journal of biological chemistry 2009;284(3):1803-12.
2009: Jun-ichi Suzuki; Mitsuaki Isobe; Ryuichi Morishita; Ryozo Nagai
Nucleic acid drugs for prevention of cardiac rejection.
Journal of biomedicine & biotechnology 2009;2009():916514.
2009: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Kazuhiko Koike; Ryozo Nagai; Minoru Yamakado
Impact of changes in waist circumference and BMI over one-year period on serum lipid data in Japanese individuals.
Journal of atherosclerosis and thrombosis 2009;16(6):764-71.
2009: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Kazuhiko Koike; Minoru Yamakado; Ryozo Nagai
Impacts of changes in obesity parameters for the prediction of blood pressure change in Japanese individuals.
Kidney & blood pressure research 2009;32(6):421-7.
2009: Jun-Ichi Suzuki; Mitsuaki Isobe; Ryuichi Morishita; Ryozo Nagai
Tea polyphenols regulate key mediators on inflammatory cardiovascular diseases.
Mediators of inflammation 2009;2009():494928.
2009: Hiroaki Sugiyama; Makoto Sahara; Yasushi Imai; Minoru Ono; Koh Okamoto; Ken Kikuchi; Ryozo Nagai
Infective endocarditis by Bartonella quintana masquerading as antineutrophil cytoplasmic antibody-associated small vessel vasculitis.
Cardiology 2009;114(3):208-11.
2009: Yuko Ishizaka; Nobukazu Ishizaka; Mizuki Tani; Akiko Toda; Ei-Ichi Toda; Kazuhiko Koike; Ryozo Nagai; Minoru Yamakado
Association between changes in obesity parameters and incidence of chronic kidney disease in Japanese individuals.
Kidney & blood pressure research 2009;32(2):141-9.
2009: Soichiro Enomoto; Masataka Sata; Daiju Fukuda; Kazuto Nakamura; Ryozo Nagai
Rosuvastatin prevents endothelial cell death and reduces atherosclerotic lesion formation in ApoE-deficient mice.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2009;63(1):19-26.
2008: Hiroaki Okazaki; Masaki Igarashi; Makiko Nishi; Motohiro Sekiya; Makiko Tajima; Satoru Takase; Mikio Takanashi; Keisuke Ohta; Yoshiaki Tamura; Sachiko Okazaki; Naoya Yahagi; Ken Ohashi; Michiyo Amemiya-Kudo; Yoshimi Nakagawa; Ryozo Nagai; Takashi Kadowaki; Jun-ichi Osuga; Shun Ishibashi
Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages.
The Journal of biological chemistry 2008;283(48):33357-64.
2008: Yasutomi Higashikuni; Tamon Nagashima; Nobukazu Ishizaka; Koichiro Kinugawa; Yasunobu Hirata; Ryozo Nagai
Right aortic arch with mirror image branching and vascular ring.
International journal of cardiology 2008;130(1):e53-5.
2008: Kazuto Nakamura; Nobutaka Koibuchi; Hiroaki Nishimatsu; Yasutomi Higashikuni; Yasunobu Hirata; Kiyotaka Kugiyama; Ryozo Nagai; Masataka Sata
Candesartan ameliorates cardiac dysfunction observed in angiotensin-converting enzyme 2-deficient mice.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(10):1953-61.
2008: Yusuke Shinoda; Naoshi Ogata; Akiro Higashikawa; Ichiro Manabe; Takayuki Shindo; Takashi Yamada; Fumitaka Kugimiya; Toshiyuki Ikeda; Naohiro Kawamura; Yosuke Kawasaki; Kensuke Tsushima; Norifumi Takeda; Ryozo Nagai; Kazuto Hoshi; Kozo Nakamura; Ung-il Chung; Hiroshi Kawaguchi
Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.
The Journal of biological chemistry 2008;283(36):24682-9.
2008: Hiroshi Iwata; Junya Ako; Ryozo Nagai
Recurrence of late-acquired incomplete stent apposition following sirolimus-eluting stent implantation.
The Journal of invasive cardiology 2008;20(9):E265-8.
2008: Kohro Takahide; Doubun Hayashi; Yoshihiro Okada; Tsutomu Yamazaki; Ryozo Nagai
Demographics and changes in medical/interventional treatment of coronary artery disease patients over a 3.5-year period in Japan: the Japanese Coronary Artery Disease Study: trend examination.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(9):1397-402.
2008: Yukari Kamijima; Nobuhiro Ooba; Mitsunori Yagame; Kazuo Samizo; Yoshihiro Shimodozono; Shigeru Kageyama; Shingo Horiguchi; Ryozo Nagai; Tadashi Kusunoki; Kiyoshi Kubota
Hypertension management in diabetic patients: prescribing trends from 1999 to 2005 in three Japanese university hospitals.
Pharmacoepidemiology and drug safety 2008;17(9):904-11.
2008: T Kariya; Yasushi Imai; Arata Murakami; Sachito Minegishi; Tatsuo Katori; Hitoshi Kato; Kohsuke Ajiki; Yasunobu Hirata; Ryozo Nagai
Images in cardiovascular medicine. Markedly dilated right heart 17 years after initial treatment repaired by total right ventricular exclusion and total cavopulmonary connection.
Circulation 2008;118(9):e133-5.
2008: Yasunobu Hirata; Arihiro Kiyosue; Masao Takahashi; Hiroshi Satonaka; Daisuke Nagata; Masataka Sata; Etsu Suzuki; Ryozo Nagai
Progression of renal dysfunction in patients with cardiovascular disease.
Current cardiology reviews 2008;4(3):198-202.
2008: Motohiro Sekiya; Jun-ichi Osuga; Naoya Yahagi; Hiroaki Okazaki; Yoshiaki Tamura; Masaki Igarashi; Satoru Takase; Kenji Harada; Sachiko Okazaki; Yoko Iizuka; Ken Ohashi; Hiroaki Yagyu; Mitsuyo Okazaki; Takanari Gotoda; Ryozo Nagai; Takashi Kadowaki; Hitoshi Shimano; Nobuhiro Yamada; Shun Ishibashi
Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis.
Journal of lipid research 2008;49(8):1829-38.
2008: Nobukazu Ishizaka; Yuko Ishizaka; George Seki; Ryozo Nagai; Minoru Yamakado; Kazuhiko Koike
Association between hepatitis B/C viral infection, chronic kidney disease and insulin resistance in individuals undergoing general health screening.
Hepatology research : the official journal of the Japan Society of Hepatology 2008;38(8):775-83.
2008: Naoto Kubota; Tetsuya Kubota; Shinsuke Itoh; Hiroki Kumagai; Hideki Kozono; Iseki Takamoto; Tomoka Mineyama; Hitomi Ogata; Kumpei Tokuyama; Miho Ohsugi; Takayoshi Sasako; Masao Moroi; Kaoru Sugi; Shigeru Kakuta; Yoichiro Iwakura; Tetsuo Noda; Shin Ohnishi; Ryozo Nagai; Kazuyuki Tobe; Yasuo Terauchi; Kohjiro Ueki; Takashi Kadowaki
Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.
Cell metabolism 2008;8(1):49-64.
2008: Gen Matsuzaki; Nobukazu Ishizaka; Kyoko Furuta; Makiko Hongo; Kan Saito; Ryota Sakurai; Kazuhiko Koike; Ryozo Nagai
Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome.
European journal of pharmacology 2008;587(1-3):237-42.
2008: Toru Suzuki; Ryozo Nagai
Molecular markers for cardiovascular disease: cardiovascular biomarkers to proteomic discovery.
Nature clinical practice. Cardiovascular medicine 2008;5(6):295.
2008: Yumiko Oishi; Ichiro Manabe; Kazuyuki Tobe; Miho Ohsugi; Tetsuya Kubota; Katsuhito Fujiu; Koji Maemura; Naoto Kubota; Takashi Kadowaki; Ryozo Nagai
SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta.
Nature medicine 2008;14(6):656-66.
2008: Satoshi Nishimura; Kinya Seo; Mika Nagasaki; Yumiko Hosoya; Hiroshi Yamashita; Hideo Fujita; Ryozo Nagai; Seiryo Sugiura
Responses of single-ventricular myocytes to dynamic axial stretching.
Progress in biophysics and molecular biology 2008;97(2-3):282-97.
2008: Ryo Takeda; Etsu Suzuki; Masao Takahashi; Shigeyoshi Oba; Hiroaki Nishimatsu; Kenjiro Kimura; Tetsuo Nagano; Ryozo Nagai; Yasunobu Hirata
Calcineurin is critical for sodium-induced neointimal formation in normotensive and hypertensive rats.
American journal of physiology. Heart and circulatory physiology 2008;294(6):H2871-8.
2008: Masao Takahashi; Etsu Suzuki; Ryo Takeda; Shigeyoshi Oba; Hiroaki Nishimatsu; Kenjiro Kimura; Tetsuo Nagano; Ryozo Nagai; Yasunobu Hirata
Angiotensin II and tumor necrosis factor-alpha synergistically promote monocyte chemoattractant protein-1 expression: roles of NF-kappaB, p38, and reactive oxygen species.
American journal of physiology. Heart and circulatory physiology 2008;294(6):H2879-88.
2008: Nanae Kada; Toru Suzuki; Kenichi Aizawa; Yoshiko Munemasa; Takayoshi Matsumura; Daigo Sawaki; Ryozo Nagai
Acyclic retinoid inhibits functional interaction of transcription factors Krüppel-like factor 5 and retinoic acid receptor-alpha.
FEBS letters 2008;582(12):1755-60.
2008: Guoqin Wang; Masafumi Watanabe; Yasushi Imai; Kazuo Hara; Ichiro Manabe; Koji Maemura; Momoko Horikoshi; Kohro Takahide; Eisuke Amiya; Takao Sugiyama; T Fujita; Takashi Kadowaki; Tsutomu Yamazaki; Ryozo Nagai
Genetic variations of Mrf-2/ARID5B confer risk of coronary atherosclerosis in the Japanese population.
International heart journal 2008;49(3):313-27.
2008: Koshiro Monzen; Yuzuru Ito; Atsuhiko T Naito; Hiroki Kasai; Yukio Hiroi; Doubun Hayashi; Ichiro Shiojima; Tsutomu Yamazaki; Kohei Miyazono; Makoto Asashima; Ryozo Nagai; Issei Komuro
A crucial role of a high mobility group protein HMGA2 in cardiogenesis.
Nature cell biology 2008;10(5):567-74.
2008: M Okamoto; Mica Ohara-Imaizumi; Naoto Kubota; S Hashimoto; Kazuhiro Eto; T Kanno; Tetsuya Kubota; M Wakui; Ryozo Nagai; Mitsuhiko Noda; S Nagamatsu; Takashi Kadowaki
Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration.
Diabetologia 2008;51(5):827-35.
2008: Hajime Fujimoto; Jun-Ichi Taguchi; Yasushi Imai; Seiji Ayabe; Hideki Hashimoto; Hisae Kobayashi; Ken Ogasawara; Tadanori Aizawa; Minoru Yamakado; Ryozo Nagai; Minoru Ohno
Manganese superoxide dismutase polymorphism affects the oxidized low-density lipoprotein-induced apoptosis of macrophages and coronary artery disease.
European heart journal 2008;29(10):1267-74.
2008: Ryozo Nagai; Tohru Izumi; Masahiko Kurabayashi; Hiroyuki Daida; Taiki Tojo; Akira Hasegawa; Katsumi Miyauchi; Doubun Hayashi; Kohro Takahide; Yoshihiro Okada; Tsutomu Yamazaki
Rationale and design of a study to examine lower targets for low-density lipoprotein-cholesterol and blood pressure in coronary artery disease patients.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(4):515-20.
2008: Miwa Matsumoto; Masataka Sata; Daiju Fukuda; Kimie Tanaka; Masaaki Soma; Yasunobu Hirata; Ryozo Nagai
Orally administered eicosapentaenoic acid reduces and stabilizes atherosclerotic lesions in ApoE-deficient mice.
Atherosclerosis 2008;197(2):524-33.
2008: Norifumi Takeda; Yoshinori Seko; Noboru Oriuchi; Ryozo Nagai
Gamma-delta T-cell-mediated dilated cardiomyopathy.
International journal of cardiology 2008;125(1):130-2.
2008: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Hiroji Shimomura; Kazuhiko Koike; George Seki; Ryozo Nagai; Minoru Yamakado
Association between cigarette smoking and chronic kidney disease in Japanese men.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(3):485-92.
2008: Kohro Takahide; Yuji Furui; Naohiro Mitsutake; Ryo Fujii; Hiroyuki Morita; Shinya Oku; Kazuhiko Ohe; Ryozo Nagai
The Japanese national health screening and intervention program aimed at preventing worsening of the metabolic syndrome.
International heart journal 2008;49(2):193-203.
2008: Makoto Sonoda; Katsu Takenaka; Kansei Uno; Aya Ebihara; Ryozo Nagai
A larger aortic annulus causes aortic regurgitation and a smaller aortic annulus causes aortic stenosis in bicuspid aortic valve.
Echocardiography (Mount Kisco, N.Y.) 2008;25(3):242-8.
2008: Yasutomi Higashikuni; Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Ryozo Nagai; Minoru Yamakado
Relationship between blood pressure and chronic kidney disease in the Japanese population: the lower the better even in individuals without hypertension?
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(2):213-9.
2008: Satoshi Nishimura; Ichiro Manabe; Mika Nagasaki; Kinya Seo; Hiroshi Yamashita; Yumiko Hosoya; Miho Ohsugi; Kazuyuki Tobe; Takashi Kadowaki; Ryozo Nagai; Seiryo Sugiura
In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue.
The Journal of clinical investigation 2008;118(2):710-21.
2008: Yoshiko Munemasa; Toru Suzuki; Kenichi Aizawa; Saku Miyamoto; Yasushi Imai; Takayoshi Matsumura; Masami Horikoshi; Ryozo Nagai
Promoter region-specific histone incorporation by the novel histone chaperone ANP32B and DNA-binding factor KLF5.
Molecular and cellular biology 2008;28(3):1171-81.
2008: Kimie Tanaka; Masataka Sata; Takeshi Natori; Joo-ri Kim-Kaneyama; Kiyoshi Nose; Motoko Shibanuma; Yasunobu Hirata; Ryozo Nagai
Circulating progenitor cells contribute to neointimal formation in nonirradiated chimeric mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(2):428-36.
2008: Makoto Sonoda; Teruhiko Aoyagi; Katsu Takenaka; Kansei Uno; Ryozo Nagai
A one-year study of the antiatherosclerotic effect of the angiotensin-II receptor blocker losartan in hypertensive patients. A comparison with angiotension-converting enzyme inhibitors.
International heart journal 2008;49(1):95-103.
2008: Yuka Ichikawa-Shindo; Takayuki Sakurai; Akiko Kamiyoshi; Hisaka Kawate; Nobuyoshi Iinuma; Takahiro Yoshizawa; Teruhide Koyama; Junichi Fukuchi; Satoshi Iimuro; Nobuo Moriyama; Hayato Kawakami; Toshinori Murata; Kenji Kangawa; Ryozo Nagai; Takayuki Shindo
The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity.
The Journal of clinical investigation 2008;118(1):29-39.
2008: Yo Tanaka; Kae Sato; Tatsuya Shimizu; Masayuki Yamato; Teruo Okano; Ichiro Manabe; Ryozo Nagai; Takehiko Kitamori
Demonstration of a bio-microactuator powered by vascular smooth muscle cells coupled to polymer micropillars.
Lab on a chip 2008;8(1):58-61.
2008: Daiju Fukuda; Masataka Sata; Nobukazu Ishizaka; Ryozo Nagai
Critical role of bone marrow angiotensin II type 1 receptor in the pathogenesis of atherosclerosis in apolipoprotein E deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(1):90-6.
2008: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Kazuhiko Koike; Minoru Yamakado; Ryozo Nagai
Are serum carcinoembryonic antigen levels associated with carotid atherosclerosis in Japanese men?
Arteriosclerosis, thrombosis, and vascular biology 2008;28(1):160-5.
2008: Po-Hsun Huang; Masataka Sata; Hiroaki Nishimatsu; Makoto Sumi; Yasunobu Hirata; Ryozo Nagai
Pioglitazone ameliorates endothelial dysfunction and restores ischemia-induced angiogenesis in diabetic mice.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2008;62(1):46-52.
2007: Masatoshi Fujita; Tsutomu Yamazaki; Dobun Hayashi; Kohro Takahide; Yoshihiro Okada; Ryozo Nagai
Comparison of cardiovascular events in patients with angiographically documented coronary narrowing with combined renin-angiotensin system inhibitor plus statin versus renin-angiotensin system inhibitor alone versus statin alone (from the Japanese Coronary Artery Disease Study).
The American journal of cardiology 2007;100(12):1750-3.
2007: Kan Saito; Takafumi Ito; Nobuko Asashima; Minoru Ohno; Ryozo Nagai; Hiromi Fujita; Nobuo Koizumi; Ai Takano; Haruo Watanabe; Hiroki Kawabata
Case report: Borrelia valaisiana infection in a Japanese man associated with traveling to foreign countries.
The American journal of tropical medicine and hygiene 2007;77(6):1124-7.
2007: Kohro Takahide; Doubun Hayashi; Yoshihiro Okada; Tsutomu Yamazaki; Ryozo Nagai
Effects of medication on cardiovascular events in the Japanese coronary artery disease (JCAD) study.
Circulation journal : official journal of the Japanese Circulation Society 2007;71(12):1835-40.
2007: Momoko Horikoshi; Kazuo Hara; Chikako Ito; Nobuhiro Shojima; Ryozo Nagai; Keisuke Ueki; philippe froguel; Takashi Kadowaki
Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.
Diabetologia 2007;50(12):2461-6.
2007: Nobukazu Ishizaka; Ryozo Nagai; Yuko Ishizaka; Ei-Ichi Toda; Minoru Yamakado; Hideki Hashimoto
Comparison of several metabolic syndrome definitions with relation to early carotid atherosclerosis in Japanese men.
Atherosclerosis 2007;195(2):e216-7; author reply e218-9.
2007: Yoshinori Takeuchi; Naoya Yahagi; Yoshimi Nakagawa; Takashi Matsuzaka; Ritsuko Shimizu; Motohiro Sekiya; Yoko Iizuka; Ken Ohashi; Takanari Gotoda; Masayuki Yamamoto; Ryozo Nagai; Takashi Kadowaki; Nobuhiro Yamada; Jun-ichi Osuga; Hitoshi Shimano
In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression.
Biochemical and biophysical research communications 2007;363(2):329-35.
2007: Norihiko Takeda; Koji Maemura; Shuichi Horie; Katsutaka Oishi; Yasushi Imai; Tomohiro Harada; Tetsuya Saito; Taro Shiga; Eisuke Amiya; Ichiro Manabe; Norio Ishida; Ryozo Nagai
Thrombomodulin is a clock-controlled gene in vascular endothelial cells.
The Journal of biological chemistry 2007;282(45):32561-7.
2007: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Kazuhiko Koike; George Seki; Ryozo Nagai; Minoru Yamakado
Association between obesity and chronic kidney disease in Japanese: differences in gender and hypertensive status?
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(11):1059-64.
2007: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Kazuhiko Koike; George Seki; Ryozo Nagai; Minoru Yamakado
Association between chronic kidney disease and carotid intima-media thickening in individuals with hypertension and impaired glucose metabolism.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(11):1035-41.
2007: Tadashi Yamazaki; Jun-Ichi Suzuki; Ryoichi Shimamoto; Taeko Tsuji; Yuki Ohmoto-Sekine; Kuni Ohtomo; Ryozo Nagai
A new therapeutic strategy for hypertrophic nonobstructive cardiomyopathy in humans. A randomized and prospective study with an Angiotensin II receptor blocker.
International heart journal 2007;48(6):715-24.
2007: Takayuki Ohno; Shinichi Takamoto; Noboru Motomura; Minoru Ono; Jiro Ando; Toshihiro Morita; Hideo Fujita; Yasunobu Hirata; Ryozo Nagai; Takashi Shigeeda; Akira Hirose
Coronary artery bypass grafting versus coronary implantation of sirolimus-eluting stents in patients with diabetic retinopathy.
The Annals of thoracic surgery 2007;84(5):1474-8.
2007: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Ryozo Nagai; Kazuhiko Koike; Hideki Hashimoto; Minoru Yamakado
Relationship between smoking, white blood cell count and metabolic syndrome in Japanese women.
Diabetes research and clinical practice 2007;78(1):72-6.
2007: Yuki Ohmoto-Sekine; Jun-ichi Suzuki; Ryoichi Shimamoto; Tadashi Yamazaki; Taeko Tsuji; Ryozo Nagai; Kuni Ohtomo
Gender-specific clinical characteristics of deep Q waves in hypertrophic cardiomyopathy.
Gender medicine 2007;4(3):274-83.
2007: Taeko Tsuji; Jun-Ichi Suzuki; Ryoichi Shimamoto; Tadashi Yamazaki; Yuki Ohomoto; Kuniaki Iwasawa; Ryozo Nagai
Morbidity prevalence rate of kawasaki disease assessed by single cross-sectional history-taking.
International heart journal 2007;48(5):615-21.
2007: Yoshiyuki Takimoto; Shoichi Maeda; Brian Taylor Slingsby; Kenji Harada; Takashi Nagase; Hirokazu Nagawa; Ryozo Nagai; Ryozo Naga; Akira Akabayashi
A template for informed consent forms in medical examination and treatment: an intervention study.
Medical science monitor : international medical journal of experimental and clinical research 2007;13(8):PH15-8.
2007: Toru Suzuki; Ryozo Nagai
Cardiovascular proteomic analysis.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;855(1):28-34.
2007: Nobukazu Ishizaka; Yuko Ishizaka; Ryozo Nagai; Ei-Ichi Toda; Hideki Hashimoto; Minoru Yamakado
Association between serum albumin, carotid atherosclerosis, and metabolic syndrome in Japanese individuals.
Atherosclerosis 2007;193(2):373-9.
2007: Naoto Kubota; Wataru Yano; Tetsuya Kubota; Toshimasa Yamauchi; Shinsuke Itoh; Hiroki Kumagai; Hideki Kozono; Iseki Takamoto; Shiki Okamoto; Tetsuya Shiuchi; Ryo Suzuki; Hidemi Satoh; Atsushi Tsuchida; Masao Moroi; Kaoru Sugi; Tetsuo Noda; Hiroyuki Ebinuma; Yoichi Ueta; Tatsuya Kondo; Eiichi Araki; Osamu Ezaki; Ryozo Nagai; Kazuyuki Tobe; Yasuo Terauchi; Kohjiro Ueki; Yasuhiko Minokoshi; Takashi Kadowaki
Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.
Cell metabolism 2007;6(1):55-68.
2007: Tsutomu Yamazaki; Shinya Goto; Hiroshi Shigematsu; Kazuyuki Shimada; Shinichiro Uchiyama; Ryozo Nagai; Nobuhiro Yamada; Masayasu Matsumoto; Hideki Origasa; Deepak L Bhatt; Philippe Gabriel STEG; Yasuo Ikeda
Prevalence, awareness and treatment of cardiovascular risk factors in patients at high risk of atherothrombosis in Japan.
Circulation journal : official journal of the Japanese Circulation Society 2007;71(7):995-1003.
2007: Nanae Kada; Toru Suzuki; Kenichi Aizawa; Takayoshi Matsumura; Naoto Ishibashi; Naomi Suzuki; Norifumi Takeda; Yoshiko Munemasa; Daigo Sawaki; Takashi Ishikawa; Ryozo Nagai
Acyclic retinoid inhibits neointima formation through retinoic acid receptor beta-induced apoptosis.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(7):1535-41.
2007: Motohiro Sekiya; Naoya Yahagi; Takashi Matsuzaka; Yoshinori Takeuchi; Yoshimi Nakagawa; Haruka Takahashi; Hiroaki Okazaki; Yoko Iizuka; Ken Ohashi; Takanari Gotoda; Shun Ishibashi; Ryozo Nagai; Tsutomu Yamazaki; Takashi Kadowaki; Nobuhiro Yamada; Jun-ichi Osuga; Hitoshi Shimano
SREBP-1-independent regulation of lipogenic gene expression in adipocytes.
Journal of lipid research 2007;48(7):1581-91.
2007: Yoshinori Seko; Hideo Yagita; Ko Okumura; Miyuki Azuma; Ryozo Nagai
Roles of programmed death-1 (PD-1)/PD-1 ligands pathway in the development of murine acute myocarditis caused by coxsackievirus B3.
Cardiovascular research 2007;75(1):158-67.
2007: Satoshi Nishimura; Ichiro Manabe; Mika Nagasaki; Yumiko Hosoya; Hiroshi Yamashita; Hideo Fujita; Miho Ohsugi; Kazuyuki Tobe; Takashi Kadowaki; Ryozo Nagai; Seiryo Sugiura
Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels.
Diabetes 2007;56(6):1517-26.
2007: Kazuto Nakamura; Masataka Sata; Hiroshi Iwata; Yoshiki Sakai; Yasunobu Hirata; Kiyotaka Kugiyama; Ryozo Nagai
A synthetic small molecule, ONO-1301, enhances endogenous growth factor expression and augments angiogenesis in the ischaemic heart.
Clinical science (London, England : 1979) 2007;112(12):607-16.
2007: Yoshinori Seko; Akihiro Matsumoto; Taira Fukuda; Yasushi Imai; Tsutomu Fujimura; Hikari Taka; Reiko Mineki; Kimie Murayama; Yasunobu Hirata; Ryozo Nagai
A case of neonatal lupus erythematosus presenting delayed dilated cardiomyopathy with circulating autoantibody to annexin A6.
International heart journal 2007;48(3):407-15.
2007: Makoto Sumi; Masataka Sata; Ayako Hashimoto; Takashi Imaizumi; Katsuhiko Yanaga; Takao Ohki; Toyoki Mori; Ryozo Nagai
OPC-28326, a selective femoral arterial vasodilator, augments ischemia induced angiogenesis.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2007;61(4):209-15.
2007: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Hideki Hashimoto; Ryozo Nagai; Minoru Yamakado
Higher serum uric acid is associated with increased arterial stiffness in Japanese individuals.
Atherosclerosis 2007;192(1):131-7.
2007: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Ryozo Nagai; Minoru Yamakado
Is metabolic syndrome a risk factor for carotid atherosclerosis in normotensive and prehypertensive individuals?
Journal of atherosclerosis and thrombosis 2007;14(2):72-7.
2007: Takayuki Ohno; Shinichi Takamoto; Jiro Ando; Toshihiro Morita; Hideo Fujita; Yasunobu Hirata; Takashi Shigeeda; Akira Hirose; Ryozo Nagai
Diabetic retinopathy and coronary implantation of sirolimus-eluting stents.
Journal of interventional cardiology 2007;20(2):122-31.
2007: Makoto Sumi; Masataka Sata; Shin-ichiro Miura; Kerry-Anne Rye; Naoki Toya; Yuji Kanaoka; Katsuhiko Yanaga; Takao Ohki; Keijiro Saku; Ryozo Nagai
Reconstituted high-density lipoprotein stimulates differentiation of endothelial progenitor cells and enhances ischemia-induced angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):813-8.
2007: Momoko Horikoshi; Kazuo Hara; Chikako Ito; Ryozo Nagai; philippe froguel; Takashi Kadowaki
A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population.
Diabetologia 2007;50(4):747-51.
2007: Toru Suzuki; Toshiya Nishi; Tomoko Nagino; Kana Sasaki; Kenichi Aizawa; Nanae Kada; Daigo Sawaki; Yoshiko Munemasa; Takayoshi Matsumura; Shinsuke Muto; Masataka Sata; Kiyoshi Miyagawa; Masami Horikoshi; Ryozo Nagai
Functional interaction between the transcription factor Krüppel-like factor 5 and poly(ADP-ribose) polymerase-1 in cardiovascular apoptosis.
The Journal of biological chemistry 2007;282(13):9895-901.
2007: Kazuo Hara; Toshimasa Yamauchi; Yasushi Imai; Ichiro Manabe; Ryozo Nagai; Takashi Kadowaki
Reduced adiponectin level is associated with severity of coronary artery disease.
International heart journal 2007;48(2):149-53.
2007: Toshimasa Yamauchi; Yasunori Nio; Toshiyuki Maki; Masaki Kobayashi; Takeshi Takazawa; Masato Iwabu; Miki Okada-Iwabu; Sachiko Kawamoto; Naoto Kubota; Tetsuya Kubota; Yusuke Ito; Junji Kamon; Atsushi Tsuchida; Katsuyoshi Kumagai; Hideki Kozono; Yusuke Hada; Hitomi Ogata; Kumpei Tokuyama; Masaki Tsunoda; Tomohiro Ide; Kouji Murakami; Motoharu Awazawa; Iseki Takamoto; philippe froguel; Kazuo Hara; Kazuyuki Tobe; Ryozo Nagai; Kohjiro Ueki; Takashi Kadowaki
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.
Nature medicine 2007;13(3):332-9.
2007: Nobukazu Ishizaka; Kan Saito; Kyoko Furuta; Gen Matsuzaki; Kazuhiko Koike; Eisei Noiri; Ryozo Nagai
Angiotensin II-induced regulation of the expression and localization of iron metabolism-related genes in the rat kidney.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(2):195-202.
2007: Koji Maemura; Norihiko Takeda; Ryozo Nagai
Circadian rhythms in the CNS and peripheral clock disorders: role of the biological clock in cardiovascular diseases.
Journal of pharmacological sciences 2007;103(2):134-8.
2007: Ibuki Shirakawa; Masataka Sata; Akio Saiura; Yukari Kaneda; Hisako Yashiro; Yasunobu Hirata; Makuuchi Masatoshi; Ryozo Nagai
Atorvastatin attenuates transplant-associated coronary arteriosclerosis in a murine model of cardiac transplantation.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2007;61(2-3):154-9.
2007: Tsuyoshi Uchiyama; Hiroyuki Atsuta; Toshihiro Utsugi; Masato Oguri; Akira Hasegawa; Tetsuya Nakamura; Akira Nakai; Masanori Nakata; Ikuro Maruyama; Hideaki Tomura; Fumikazu Okajima; Shoichi Tomono; Shoji Kawazu; Ryozo Nagai; Masahiko Kurabayashi
HSF1 and constitutively active HSF1 improve vascular endothelial function (heat shock proteins improve vascular endothelial function).
Atherosclerosis 2007;190(2):321-9.
2007: Makoto Sahara; Masataka Sata; Toshihiro Morita; Kazuto Nakamura; Yasunobu Hirata; Ryozo Nagai
Diverse contribution of bone marrow-derived cells to vascular remodeling associated with pulmonary arterial hypertension and arterial neointimal formation.
Circulation 2007;115(4):509-17.
2007: Makoto Sumi; Masataka Sata; Naoki Toya; Katsuhiko Yanaga; Takao Ohki; Ryozo Nagai
Transplantation of adipose stromal cells, but not mature adipocytes, augments ischemia-induced angiogenesis.
Life sciences 2007;80(6):559-65.
2007: Kazuo Asada; Masaru Hatano; Norihiko Takeda; Yasutomi Higashikuni; Kan Saito; Nobukazu Ishizaka; Yasunobu Hirata; Ryozo Nagai
Giant left coronary artery aneurysm in a patient with mixed connective tissue disease.
Internal medicine (Tokyo, Japan) 2007;46(15):1267-8.
2007: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Ryozo Nagai; Minoru Yamakado
Association between cigarette smoking, white blood cell count, and metabolic syndrome as defined by the Japanese criteria.
Internal medicine (Tokyo, Japan) 2007;46(15):1167-70.
2007: Kensaku Nishihira; Takuroh Imamura; Kinta Hatakeyama; Atsushi Yamashita; Yoshisato Shibata; Haruhiko Date; Ichiro Manabe; Ryozo Nagai; Kazuo Kitamura; Yujiro Asada
Expression of interleukin-18 in coronary plaque obtained by atherectomy from patients with stable and unstable angina.
Thrombosis research 2007;121(2):275-9.
2007: Yasuo Terauchi; Iseki Takamoto; Naoto Kubota; Junji Matsui; Ryo Suzuki; Kajuro Komeda; Akemi Hara; Yukiyasu Toyoda; Ichitomo Miwa; Shinichi Aizawa; Shuichi Tsutsumi; Yoshiharu Tsubamoto; Shinji Hashimoto; Kazuhiro Eto; Akinobu Nakamura; Mitsuhiko Noda; Kazuyuki Tobe; Hiroyuki Aburatani; Ryozo Nagai; Takashi Kadowaki
Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.
The Journal of clinical investigation 2007;117(1):246-57.
2006: Takayoshi Matsumura; Toru Suzuki; Nanae Kada; Kenichi Aizawa; Yoshiko Munemasa; Ryozo Nagai
Differential serum proteomic analysis in a model of metabolic disease.
Biochemical and biophysical research communications 2006;351(4):965-71.
2006: Yumiko Oishi; Ichiro Manabe; Ryozo Nagai
[Krüppel-like transcription factor 5 (KLF5)].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 9():254-8.
2006: Satoshi Nishimura; Yasuo Kawai; Toshiaki Nakajima; Yumiko Hosoya; Hideo Fujita; Masayoshi Katoh; Hiroshi Yamashita; Ryozo Nagai; Seiryo Sugiura
Membrane potential of rat ventricular myocytes responds to axial stretch in phase, amplitude and speed-dependent manners.
Cardiovascular research 2006;72(3):403-11.
2006: Nobukazu Ishizaka; Gen Matsuzaki; Kan Saito; Eisei Noiri; Ichiro Mori; Ryozo Nagai
Expression and localization of PDGF-B, PDGF-D, and PDGF receptor in the kidney of angiotensin II-infused rat.
Laboratory investigation; a journal of technical methods and pathology 2006;86(12):1285-92.
2006: Kazuyuki Hanajiri; Toshiyuki Maruyama; Yukio Kaneko; Hiroshi Mitsui; Shunsuke Watanabe; Masataka Sata; Ryozo Nagai; Takeshi Kashima; Junji Shibahara; Masao Omata; Yoichiro Matsumoto
Microbubble-induced increase in ablation of liver tumors by high-intensity focused ultrasound.
Hepatology research : the official journal of the Japan Society of Hepatology 2006;36(4):308-14.
2006: Minami Abe; Masataka Sata; Etsu Suzuki; Ryo Takeda; Masao Takahashi; Hiroaki Nishimatsu; Daisuke Nagata; Kenji Kangawa; Hisayuki Matsuo; Ryozo Nagai; Yasunobu Hirata
Effects of adrenomedullin on acute ischaemia-induced collateral development and mobilization of bone-marrow-derived cells.
Clinical science (London, England : 1979) 2006;111(6):381-7.
2006: Kansei Uno; Katsu Takenaka; Kenichi Asada; Aya Ebihara; Kazuno Sasaki; Takako Komuro; Ryozo Nagai; Noboru Motomura; Minoru Ono; Shinichi Takamoto
Diagnosis of subacute cardiac rupture by contrast echocardiography.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2006;19(11):1401.e9-1401.e11.
2006: Makoto Sahara; Toshiyuki Takahashi; Yasushi Imai; Toshiaki Nakajima; Atsushi Yao; Toshihiro Morita; Yasunobu Hirata; Ryozo Nagai
New insights in the treatment strategy for pulmonary arterial hypertension.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2006;20(5):377-86.
2006: Tsuyoshi Uchiyama; Hiroyuki Atsuta; Toshihiro Utsugi; Yoshio Ohyama; Tetsuya Nakamura; Akira Nakai; Masanori Nakata; Ikuro Maruyama; Hideaki Tomura; Fumikazu Okajima; Shoichi Tomono; Shoji Kawazu; Ryozo Nagai; Masahiko Kurarbayashi
Simvastatin induces heat shock factor 1 in vascular endothelial cells.
Atherosclerosis 2006;188(2):265-73.
2006: Hiroshi Doi; Tatsuya Iso; Hiroko Sato; Miki Yamazaki; Hiroki Matsui; Toru Tanaka; Ichiro Manabe; Masashi Arai; Ryozo Nagai; Masahiko Kurabayashi
Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jkappa-dependent pathway.
The Journal of biological chemistry 2006;281(39):28555-64.
2006: Nozomu Kamei; Kazuyuki Tobe; Ryo Suzuki; Miho Ohsugi; Taku Watanabe; Naoto Kubota; Norie Ohtsuka-Kowatari; Katsuyoshi Kumagai; Kentaro Sakamoto; Masatoshi Kobayashi; Toshimasa Yamauchi; Kohjiro Ueki; Yumiko Oishi; Satoshi Nishimura; Ichiro Manabe; Haruo Hashimoto; Yasuyuki Ohnishi; Hitomi Ogata; Kumpei Tokuyama; Masaki Tsunoda; Tomohiro Ide; Koji Murakami; Ryozo Nagai; Takashi Kadowaki
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.
The Journal of biological chemistry 2006;281(36):26602-14.
2006: Shin-ichi Usui; Atsushi Yao; Masaru Hatano; Osami Kohmoto; Toshiyuki Takahashi; Ryozo Nagai; Koichiro Kinugawa
Upregulated neurohumoral factors are associated with left ventricular remodeling and poor prognosis in rats with monocrotaline-induced pulmonary arterial hypertension.
Circulation journal : official journal of the Japanese Circulation Society 2006;70(9):1208-15.
2006: Nobukazu Ishizaka; Yuko Ishizaka; Hideki Hashimoto; Ei-Ichi Toda; Ryozo Nagai; Minoru Yamakado
Metabolic syndrome may not associate with carotid plaque in subjects with optimal, normal, or high-normal blood pressure.
Hypertension 2006;48(3):411-7.
2006: Aiko Sakamoto; Koji Okamoto; Nobukazu Ishizaka; Kazuaki Tejima; Yasunobu Hirata; Ryozo Nagai
18F-fluorodeoxyglucose positron emission tomography in a case of retroperitoneal fibrosis.
International heart journal 2006;47(4):645-50.
2006: Yuichiro Saito; Masahiko Kurabayashi; Tetsuya Nakamura; Ryozo Nagai
[Klotho gene].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 5():403-6.
2006: Go Nishimura; Ichiro Manabe; Kensuke Tsushima; Katsuhito Fujiu; Yumiko Oishi; Yasushi Imai; Koji Maemura; Makoto Miyagishi; Yujiro Higashi; Hisato Kondoh; Ryozo Nagai
DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation.
Developmental cell 2006;11(1):93-104.
2006: Kazuo Hara; Momoko Horikoshi; Toshimasa Yamauchi; Hirokazu Yago; Osamu Miyazaki; Hiroyuki Ebinuma; Yasushi Imai; Ryozo Nagai; Takashi Kadowaki
Measurement of the high-molecular weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.
Diabetes care 2006;29(6):1357-62.
2006: Satoshi Nishimura; Shinya Nagai; Masataka Sata; Masayoshi Katoh; Hiroshi Yamashita; Yasutake Saeki; Ryozo Nagai; Seiryo Sugiura
Expression of green fluorescent protein impairs the force-generating ability of isolated rat ventricular cardiomyocytes.
Molecular and cellular biochemistry 2006;286(1-2):59-65.
2006: Ikuo Yokoyama; Yusuke Inoue; Toshiyuki Moritan; Kuni Ohtomo; Ryozo Nagai
Myocardial glucose utilisation in type II diabetes mellitus patients treated with sulphonylurea drugs.
European journal of nuclear medicine and molecular imaging 2006;33(6):703-8.
2006: Yuichiro Saito; Masahiko Kurabayashi; Tetsuya Nakamura; Ryozo Nagai
[Klotho gene and endothelial function].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2006;43(3):342-4.
2006: Takayoshi Matsumura; Akihiro Matsumoto; Minoru Ohno; Shinya Suzuki; Miki Ohta; Etsu Suzuki; Katsu Takenaka; Yasunobu Hirata; Toshiro Fujita; Ryozo Nagai
A case of cholesterol embolism confirmed by skin biopsy and successfully treated with statins and steroids.
The American journal of the medical sciences 2006;331(5):280-3.
2006: Kazuo Hara; Momoko Horikoshi; Hiroshi Kitazato; Chikako Ito; Mitsuhiko Noda; Jun Ohashi; philippe froguel; Katsushi Tokunaga; Kazuyuki Tobe; Ryozo Nagai; Takashi Kadowaki
Hepatocyte nuclear factor-4alpha P2 promoter haplotypes are associated with type 2 diabetes in the Japanese population.
Diabetes 2006;55(5):1260-4.
2006: Norifumi Takeda; Ichiro Manabe; Takayuki Shindo; Hiroshi Iwata; Satoshi Iimuro; Hiroyuki Kagechika; Koichi Shudo; Ryozo Nagai
Synthetic retinoid Am80 reduces scavenger receptor expression and atherosclerosis in mice by inhibiting IL-6.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(5):1177-83.
2006: Momoko Horikoshi; Kazuo Hara; Jun Ohashi; Kazuaki Miyake; Katsushi Tokunaga; Chikako Ito; Masato Kasuga; Ryozo Nagai; Takashi Kadowaki
A polymorphism in the AMPKalpha2 subunit gene is associated with insulin resistance and type 2 diabetes in the Japanese population.
Diabetes 2006;55(4):919-23.
2006: Naoto Kubota; Yasuo Terauchi; Tetsuya Kubota; Hiroki Kumagai; Shinsuke Itoh; Hidemi Satoh; Wataru Yano; Hitomi Ogata; Kumpei Tokuyama; Iseki Takamoto; Tomoka Mineyama; Michiro Ishikawa; Masao Moroi; Kaoru Sugi; Toshimasa Yamauchi; Kohjiro Ueki; Kazuyuki Tobe; Tetsuo Noda; Ryozo Nagai; Takashi Kadowaki
Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways.
The Journal of biological chemistry 2006;281(13):8748-55.
2006: Tadashi Yamazaki; Jun-ichi Suzuki; Ryoichi Shimamoto; Taeko Tsuji; Yuki Ohmoto; Teruhiko Toyo-Oka; Masao Omata; Kuni Ohtomo; Ryozo Nagai
Focalized contractile impairment at hypertrophied myocardium proven in consideration of wall stress in patients with hypertrophic cardiomyopathy.
International heart journal 2006;47(2):247-58.
2006: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Ryozo Nagai; Minoru Yamakado
Association between smoking, hematological parameters, and metabolic syndrome in Japanese men.
Diabetes care 2006;29(3):741.
2006: Daiji Kawanami; Koji Maemura; Norihiko Takeda; Tomohiro Harada; Takefumi Nojiri; Tetsuya Saito; Ichiro Manabe; Yasushi Imai; Ryozo Nagai
C-reactive protein induces VCAM-1 gene expression through NF-kappaB activation in vascular endothelial cells.
Atherosclerosis 2006;185(1):39-46.
2006: Ji Ma; Shinya Kishida; Guo Qin Wang; Kentarou Meguro; Hiroyuki Imuta; Hitoshi Oonuma; Haruko Iida; Taisuke Jo; Haruhito Takano; Toshihiro Morita; Ryozo Nagai; Toshiaki Nakajima
Comparative effects of azelnidipine and other Ca2+-channel blockers on the induction of inducible nitric oxide synthase in vascular smooth muscle cells.
Journal of cardiovascular pharmacology 2006;47(2):314-21.
2006: Satoshi Nishimura; Shinya Nagai; Masayoshi Katoh; Hiroshi Yamashita; Yasutake Saeki; Jun-ichi Okada; Toshiaki Hisada; Ryozo Nagai; Seiryo Sugiura
Microtubules modulate the stiffness of cardiomyocytes against shear stress.
Circulation research 2006;98(1):81-7.
2006: Tsutomu Shimizu; Norifumi Takeda; Masao Takahashi; Yasushi Imai; Nobukazu Ishizaka; Yasunobu Hirata; Ryozo Nagai
Subarachnoid hemorrhage from mycotic aneurysms.
Internal medicine (Tokyo, Japan) 2006;45(20):1189-90.
2006: Makoto Sahara; Toshiyuki Takahashi; Toshihiro Morita; Atsushi Yao; Yu Nagashima; Yasunobu Hirata; Ryozo Nagai
Three-vessel coronary artery disease complicated with congestive heart failure in a highly aged patient with tetralogy of Fallot having undergone palliative surgeries.
Internal medicine (Tokyo, Japan) 2006;45(20):1147-51.
2006: Koji Kawakami; Oumi Nakajima; Ryuichi Morishita; Ryozo Nagai
Targeted anticancer immunotoxins and cytotoxic agents with direct killing moieties.
TheScientificWorldJournal 2006;6():781-90.
2006: Shinya Kishida; Toshiaki Nakajima; Ji Ma; Taisuke Jo; Hiroyuki Imuta; Hitoshi Oonuma; Haruko Iida; Haruhito Takano; Toshihiro Morita; Ryozo Nagai
Amiodarone and N-desethylamiodarone enhance endothelial nitric oxide production in human endothelial cells.
International heart journal 2006;47(1):85-93.
2006: Ryo Takeda; Hiroaki Nishimatsu; Etsu Suzuki; Hiroshi Satonaka; Daisuke Nagata; Shigeyoshi Oba; Masataka Sata; Masao Takahashi; Yuji Yamamoto; Yasuo Terauchi; Takashi Kadowaki; Kenji Kangawa; Tadaichi Kitamura; Ryozo Nagai; Yasunobu Hirata
Ghrelin improves renal function in mice with ischemic acute renal failure.
Journal of the American Society of Nephrology : JASN 2006;17(1):113-21.
2005: Katsuhito Fujiu; Ichiro Manabe; Atsushi Ishihara; Yumiko Oishi; Hiroshi Iwata; Go Nishimura; Takayuki Shindo; Koji Maemura; Hiroyuki Kagechika; Koichi Shudo; Ryozo Nagai
Synthetic retinoid Am80 suppresses smooth muscle phenotypic modulation and in-stent neointima formation by inhibiting KLF5.
Circulation research 2005;97(11):1132-41.
2005: Koshiro Monzen; Toru Hosoda; Doubun Hayashi; Yasushi Imai; Yasuhiro Okawa; Kohro Takahide; Hiroshi Uozaki; Tomoki Nishiyama; Masashi Fukayama; Ryozo Nagai
The use of a supercooling refrigerator improves the preservation of organ grafts.
Biochemical and biophysical research communications 2005;337(2):534-9.
2005: Kan Saito; Nobukazu Ishizaka; Masumi Hara; Gen Matsuzaki; Masataka Sata; Ichiro Mori; Minoru Ohno; Ryozo Nagai
Lipid accumulation and transforming growth factor-beta upregulation in the kidneys of rats administered angiotensin II.
Hypertension 2005;46(5):1180-5.
2005: Nobukazu Ishizaka; Kan Saito; Ichiro Mori; Gen Matsuzaki; Minoru Ohno; Ryozo Nagai
Iron chelation suppresses ferritin upregulation and attenuates vascular dysfunction in the aorta of angiotensin II-infused rats.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(11):2282-8.
2005: Haruhito Takano; Toshihiro Morita; Haruko Iida; Ken-ichi Asada; Masayoshi Kato; Kansei Uno; Ken Hirose; Akihiro Matsumoto; Katsu Takenaka; Yasunobu Hirata; Fumio Eto; Ryozo Nagai; Yoshiaki Sato; Toshiaki Nakajima
Hemodynamic and hormonal responses to a short-term low-intensity resistance exercise with the reduction of muscle blood flow.
European journal of applied physiology 2005;95(1):65-73.
2005: Haruko Iida; Taisuke Jo; Kuniaki Iwasawa; Toshihiro Morita; Hisako Hikiji; Tsuyoshi Takato; Teruhiko Toyo-Oka; Ryozo Nagai; Toshiaki Nakajima
Molecular and pharmacological characteristics of transient voltage-dependent K+ currents in cultured human pulmonary arterial smooth muscle cells.
British journal of pharmacology 2005;146(1):49-59.
2005: Hiroko Sato; Mahito Sato; Hiroyoshi Kanai; Tsuyoshi Uchiyama; Tatsuya Iso; Yoshio Ohyama; Hironosuke Sakamoto; Jun'ichi Tamura; Ryozo Nagai; Masahiko Kurabayashi
Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells.
Cardiovascular research 2005;67(4):714-22.
2005: Ryozo Nagai; Takahiro Suzuki; Kenichi Aizawa; Takayuki Shindo; Ichiro Manabe
Significance of the transcription factor KLF5 in cardiovascular remodeling.
Journal of thrombosis and haemostasis : JTH 2005;3(8):1569-76.
2005: Yasushi Imai; Tsuyoshi Taketani; Koji Maemura; Norihiko Takeda; Tomohiro Harada; Takefumi Nojiri; Daiji Kawanami; Koshiro Monzen; Doubun Hayashi; Yuji Murakawa; Minoru Ohno; Yoshinobu Hirata; Tsutomu Yamazaki; Shinichi Takamoto; Ryozo Nagai
Genetic analysis in a patient with recurrent cardiac myxoma and endocrinopathy.
Circulation journal : official journal of the Japanese Circulation Society 2005;69(8):994-5.
2005: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Hideki Hashimoto; Ryozo Nagai; Minoru Yamakado
Association between cigarette smoking, metabolic syndrome, and carotid arteriosclerosis in Japanese individuals.
Atherosclerosis 2005;181(2):381-8.
2005: Makoto Sahara; Masataka Sata; Yumi Matsuzaki; Kimie Tanaka; Toshihiro Morita; Yasunobu Hirata; Hideyuki Okano; Ryozo Nagai
Comparison of various bone marrow fractions in the ability to participate in vascular remodeling after mechanical injury.
Stem cells (Dayton, Ohio) 2005;23(7):874-8.
2005: Satoshi Nishimura; Hiroshi Yamashita; Masayoshi Katoh; Kelly P Yamada; Kenji Sunagawa; Yasutake Saeki; Yosiki Ohnuki; Ryozo Nagai; Seiryo Sugiura
Contractile dysfunction of cardiomyopathic hamster myocytes is pronounced under high load conditions.
Journal of molecular and cellular cardiology 2005;39(2):231-9.
2005: Yuho Najima; Naoya Yahagi; Yoshinori Takeuchi; Takashi Matsuzaka; Motohiro Sekiya; Yoshimi Nakagawa; Michiyo Amemiya-Kudo; Hiroaki Okazaki; Sachiko Okazaki; Yoshiaki Tamura; Yoko Iizuka; Ken Ohashi; Kenji Harada; Takanari Gotoda; Ryozo Nagai; Takashi Kadowaki; Shun Ishibashi; Nobuhiro Yamada; Jun-ichi Osuga; Hitoshi Shimano
High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding.
The Journal of biological chemistry 2005;280(30):27523-32.
2005: Sahohime Matsumoto; Makoto Miyagishi; Hideo Akashi; Ryozo Nagai; Kazunari Taira
Analysis of double-stranded RNA-induced apoptosis pathways using interferon-response noninducible small interfering RNA expression vector library.
The Journal of biological chemistry 2005;280(27):25687-96.
2005: Kimie Tanaka; Masataka Sata; Daiju Fukuda; Yoshihiro Suematsu; Noboru Motomura; Shinichi Takamoto; Yasunobu Hirata; Ryozo Nagai
Age-associated aortic stenosis in apolipoprotein E-deficient mice.
Journal of the American College of Cardiology 2005;46(1):134-41.
2005: Tomohiro Harada; Ryozo Nagai
[The genetic disorders responsible for sudden cardiac death].
Nihon rinsho. Japanese journal of clinical medicine 2005;63(7):1273-83.
2005: Takashi Ishikawa; Yasushi Fukushima; Yujiro Shiobara; Tsuyoshi Kishimoto; Sakiko Tanno; Ikuo Shoji; Tetsuro Suzuki; Tamano Matsui; Yasushi Shimada; Takaaki Ohyama; Ryozo Nagai; Tatsuo Miyamura
Outbreak of hepatitis C virus infection in an outpatient clinic.
Journal of gastroenterology and hepatology 2005;20(7):1087-93.
2005: Kazuo Hara; Momoko Horikoshi; Hiroshi Kitazato; T Yamauchi; Chikako Ito; Mitsuhiko Noda; Jun Ohashi; philippe froguel; Katsushi Tokunaga; Ryozo Nagai; Takashi Kadowaki
Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes.
Diabetologia 2005;48(7):1307-14.
2005: Taisuke Jo; Haruko Iida; Shinya Kishida; Hiroyuki Imuta; Hitoshi Oonuma; Taiji Nagata; Hajime Hara; Kuniaki Iwasawa; Masaaki Soma; Yoshiaki Sato; Takashi Nagase; Ryozo Nagai; Toshiaki Nakajima
Acute and chronic effects of eicosapentaenoic acid on voltage-gated sodium channel expressed in cultured human bronchial smooth muscle cells.
Biochemical and biophysical research communications 2005;331(4):1452-9.
2005: Eisuke Amiya; Nobukazu Ishizaka; Airi Watanabe; Yoko Endo; Rei Itou; Shigetaka Yoshida; Masahumi Nangaku; Ryozo Nagai
Retroperitoneal fibrosis with periaortic and pericardial involvement.
Circulation journal : official journal of the Japanese Circulation Society 2005;69(6):760-2.
2005: Naoya Yahagi; Hitoshi Shimano; Kiyoshi Hasegawa; Ken Ohashi; Takashi Matsuzaka; Yuho Najima; Motohiro Sekiya; Sachiko Tomita; Hiroaki Okazaki; Yoshiaki Tamura; Yoko Iizuka; Kenichi Ohashi; Ryozo Nagai; Shun Ishibashi; Takashi Kadowaki; Makuuchi Masatoshi; Shin Ohnishi; Jun-ichi Osuga; Nobuhiro Yamada
Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma.
European journal of cancer (Oxford, England : 1990) 2005;41(9):1316-22.
2005: Toru Suzuki; Kenichi Aizawa; Takayoshi Matsumura; Ryozo Nagai
Vascular implications of the Krüppel-like family of transcription factors.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(6):1135-41.
2005: Toru Suzuki; Takayoshi Matsumura; Ryozo Nagai
Transcriptional regulation at the chromatin level in the cardiovasculature through protein-protein interactions and chemical modifications.
Trends in cardiovascular medicine 2005;15(4):125-9.
2005: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Ryozo Nagai; Minoru Yamakado
Association between serum uric acid, metabolic syndrome, and carotid atherosclerosis in Japanese individuals.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(5):1038-44.
2005: Hiroyuki Morita; Yuichiro Saito; Noriko Ohashi; Masayoshi Yoshikawa; Makoto Katoh; Terunao Ashida; Hiroki Kurihara; Tetsuya Nakamura; Masahiko Kurabayashi; Ryozo Nagai
Fluvastatin ameliorates the hyperhomocysteinemia-induced endothelial dysfunction: the antioxidative properties of fluvastatin.
Circulation journal : official journal of the Japanese Circulation Society 2005;69(4):475-80.
2005: Takayoshi Matsumura; Toru Suzuki; Kenichi Aizawa; Yoshiko Munemasa; Shinsuke Muto; Masami Horikoshi; Ryozo Nagai
The deacetylase HDAC1 negatively regulates the cardiovascular transcription factor Krüppel-like factor 5 through direct interaction.
The Journal of biological chemistry 2005;280(13):12123-9.
2005: Nobukazu Ishizaka; Kan Saito; Eisei Noiri; Masataka Sata; Hitoshi Ikeda; Akihiko Ohno; Jiro Ando; Ichiro Mori; Minoru Ohno; Ryozo Nagai
Administration of ANG II induces iron deposition and upregulation of TGF-beta1 mRNA in the rat liver.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;288(4):R1063-70.
2005: Kan Saito; Nobukazu Ishizaka; Tadanori Aizawa; Masataka Sata; Naoyuki Iso-o; Eisei Noiri; Ichiro Mori; Minoru Ohno; Ryozo Nagai
Iron chelation and a free radical scavenger suppress angiotensin II-induced upregulation of TGF-beta1 in the heart.
American journal of physiology. Heart and circulatory physiology 2005;288(4):H1836-43.
2005: Hiroaki Nishimatsu; Etsu Suzuki; Hiroshi Satonaka; Ryo Takeda; Masao Omata; Toshiro Fujita; Ryozo Nagai; Tadaichi Kitamura; Yasunobu Hirata
Endothelial dysfunction and hypercontractility of vascular myocytes are ameliorated by fluvastatin in obese Zucker rats.
American journal of physiology. Heart and circulatory physiology 2005;288(4):H1770-6.
2005: Ryo Takeda; Etsu Suzuki; Hiroshi Satonaka; Shigeyoshi Oba; Hiroaki Nishimatsu; Masao Omata; Toshiro Fujita; Ryozo Nagai; Yasunobu Hirata
Blockade of endogenous cytokines mitigates neointimal formation in obese Zucker rats.
Circulation 2005;111(11):1398-406.
2005: Norimichi Koitabashi; Masashi Arai; Koichi Tomaru; Takako Takizawa; Atai Watanabe; Kazuo Niwano; Tomoyuki Yokoyama; Frank Wuytack; Muthu Periasamy; Ryozo Nagai; Masahiko Kurabayashi
Carvedilol effectively blocks oxidative stress-mediated downregulation of sarcoplasmic reticulum Ca2+-ATPase 2 gene transcription through modification of Sp1 binding.
Biochemical and biophysical research communications 2005;328(1):116-24.
2005: Tsuyoshi Taketani; Yasushi Imai; Tetsuro Morota; Koji Maemura; Hiroyuki Morita; Doubun Hayashi; Tsutomu Yamazaki; Ryozo Nagai; Shinichi Takamoto
Altered patterns of gene expression specific to thoracic aortic aneurysms: microarray analysis of surgically resected specimens.
International heart journal 2005;46(2):265-77.
2005: Norifumi Takeda; Toshiyuki Takahashi; Yoshinori Seko; Koji Maemura; Hideki Nakasone; Kei Sakamoto; Yasunobu Hirata; Ryozo Nagai
Takayasu myocarditis mediated by cytotoxic T lymphocytes.
Internal medicine (Tokyo, Japan) 2005;44(3):256-60.
2005: Daiju Fukuda; Masataka Sata; Kimie Tanaka; Ryozo Nagai
Potent inhibitory effect of sirolimus on circulating vascular progenitor cells.
Circulation 2005;111(7):926-31.
2005: Yasutomi Higashikuni; Masataka Sata; Ryozo Nagai
Reversible left ventricular hypertrophy after tako-tsubo-like cardiomyopathy.
Acta cardiologica 2005;60(1):77-9.
2005: Mahito Sato; Keiko Kawai-Kowase; Hiroko Sato; Yuko Oyama; Hiroyoshi Kanai; Yoshio Ohyama; Tatsuo Suga; Toshitaka Maeno; Yasuhiro Aoki; Jun'ichi Tamura; Hironosuke Sakamoto; Ryozo Nagai; Masahiko Kurabayashi
c-Src and hydrogen peroxide mediate transforming growth factor-beta1-induced smooth muscle cell-gene expression in 10T1/2 cells.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(2):341-7.
2005: Yumiko Oishi; Ichiro Manabe; Kazuyuki Tobe; Kensuke Tsushima; Takayuki Shindo; Katsuhito Fujiu; Go Nishimura; Koji Maemura; Toshimasa Yamauchi; Naoto Kubota; Ryo Suzuki; Toshio Kitamura; Shizuo Akira; Takashi Kadowaki; Ryozo Nagai
Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation.
Cell metabolism 2005;1(1):27-39.
2005: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Hideki Hashimoto; Ryozo Nagai; Minoru Yamakado
Hypertension is the most common component of metabolic syndrome and the greatest contributor to carotid arteriosclerosis in apparently healthy Japanese individuals.
Hypertension research : official journal of the Japanese Society of Hypertension 2005;28(1):27-34.
2005: Takeshi Natori; Masataka Sata; Ryozo Nagai; Makuuchi Masatoshi
Cimetidine inhibits angiogenesis and suppresses tumor growth.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2005;59(1-2):56-60.
2005: Ikuo Yokoyama; Yusuke Inoue; Toshiyuki Moritan; Kuni Ohtomo; Ryozo Nagai
Measurement of skeletal muscle glucose utilization by dynamic 18F-FDG PET without arterial blood sampling.
Nuclear medicine communications 2005;26(1):31-7.
2004: Ji Ma; Haruko Iida; Taisuke Jo; Haruhito Takano; Hitoshi Oonuma; Toshihiro Morita; Teruhiko Toyo-Oka; Masao Omata; Ryozo Nagai; Yukichi Okuda; Nobuhiro Yamada; Toshiaki Nakajima
Ursodeoxycholic acid inhibits endothelin-1 production in human vascular endothelial cells.
European journal of pharmacology 2004;505(1-3):67-74.
2004: Yasushi Fukushima; Toshimitsu Matsui; Toshihito Saitoh; Masao Ichinose; Keisuke Tateishi; Takayuki Shindo; Midori Fujishiro; Hideyuki Sakoda; Nobuhiro Shojima; Akifumi Kushiyama; Satoru Fukuda; Motonobu Anai; Hiraku Ono; Masashi Oka; Yasuhito Shimizu; Hiroki Kurihara; Ryozo Nagai; Takashi Ishikawa; Tomoichiro Asano; Masao Omata
Unique roles of G protein-coupled histamine H2 and gastrin receptors in growth and differentiation of gastric mucosa.
European journal of pharmacology 2004;502(3):243-52.
2004: Susumu Sakurai; Katsu Takenaka; Ichiro Shiojima; Makoto Sonoda; Kansei Uno; Kazuhiko Nakahara; Ryozo Nagai
Close physical contact of the heart with diaphragm causes pseudo-asynergy of left ventricular inferior wall in normal subjects.
Echocardiography (Mount Kisco, N.Y.) 2004;21(7):573-9.
2004: Naoto Kubota; Yasuo Terauchi; Kazuyuki Tobe; Wataru Yano; Ryo Suzuki; Kohjiro Ueki; Iseki Takamoto; Hidemi Satoh; Toshiyuki Maki; Tetsuya Kubota; Masao Moroi; Miki Okada-Iwabu; Osamu Ezaki; Ryozo Nagai; Yoichi Ueta; Takashi Kadowaki; Tetsuo Noda
Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.
The Journal of clinical investigation 2004;114(7):917-27.
2004: Hajime Fujimoto; Minoru Ohno; Seiji Ayabe; Hisae Kobayashi; Nobukazu Ishizaka; Hiroko Kimura; Ken-ichi Yoshida; Ryozo Nagai
Carbon monoxide protects against cardiac ischemia--reperfusion injury in vivo via MAPK and Akt--eNOS pathways.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1848-53.
2004: Akio Saiura; Masataka Sata; Ken-ichi Hiasa; Shiro Kitamoto; Miwa Washida; Kensuke Egashira; Ryozo Nagai; Makuuchi Masatoshi
Antimonocyte chemoattractant protein-1 gene therapy attenuates graft vasculopathy.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1886-90.
2004: Doubun Hayashi; Sumiyo Kudoh; Ichiro Shiojima; Yunzeng Zou; Koichiro Harada; Masaki Shimoyama; Yasushi Imai; Koshiro Monzen; Tsutomu Yamazaki; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Atrial natriuretic peptide inhibits cardiomyocyte hypertrophy through mitogen-activated protein kinase phosphatase-1.
Biochemical and biophysical research communications 2004;322(1):310-9.
2004: Masayoshi Kato; Akihiro Matsumoto; Toshiaki Nakajima; Ken Hirose; Kuniaki Iwasawa; Katsu Takenaka; Hiroshi Yamashita; Seiryo Sugiura; Yasunobu Hirata; Ryozo Nagai
Amlodipine increases nitric oxide production in exhaled air during exercise in patients with essential hypertension.
American journal of hypertension 2004;17(9):729-33.
2004: Yuko Oyama; Keiko Kawai-Kowase; Kenichi Sekiguchi; Mahito Sato; Hiroko Sato; Miki Yamazaki; Yoshio Ohyama; Yasushi Aihara; Tatsuya Iso; Eichi Okamaoto; Ryozo Nagai; Masahiko Kurabayashi
Homeobox protein Hex facilitates serum responsive factor-mediated activation of the SM22alpha gene transcription in embryonic fibroblasts.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(9):1602-7.
2004: Satoshi Iimuro; Takayuki Shindo; Nobuo Moriyama; Toshihiro Amaki; Pei Niu; Norifumi Takeda; Hiroshi Iwata; Yuelan Zhang; Aya Ebihara; Ryozo Nagai
Angiogenic effects of adrenomedullin in ischemia and tumor growth.
Circulation research 2004;95(4):415-23.
2004: Kan Saito; Nobukazu Ishizaka; Tadanori Aizawa; Masataka Sata; Naoyuki Iso-o; Eisei Noiri; Minoru Ohno; Ryozo Nagai
Role of aberrant iron homeostasis in the upregulation of transforming growth factor-beta1 in the kidney of angiotensin II-induced hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2004;27(8):599-607.
2004: Hiroyuki Morita; Ikuo Yokoyama; Namie Yamada; Kansei Uno; Ryozo Nagai
Usefulness of 18FDG/13N-ammonia PET imaging for evaluation of the cardiac damage in Churg-Strauss syndrome.
European journal of nuclear medicine and molecular imaging 2004;31(8):1218.
2004: Tokuyuki Yamashita; Kazuhiro Eto; Yukiko Okazaki; Shigeo Yamashita; Toshimasa Yamauchi; Nobuo Sekine; Ryozo Nagai; Mitsuhiko Noda; Takashi Kadowaki
Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a beta-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c.
Endocrinology 2004;145(8):3566-77.
2004: Mahito Sato; Toru Tanaka; Koji Maemura; Tsuyoshi Uchiyama; Hiroko Sato; Toshitaka Maeno; Tatsuo Suga; Tatsuya Iso; Yoshio Ohyama; Masashi Arai; Jun'ichi Tamura; Hironosuke Sakamoto; Ryozo Nagai; Masahiko Kurabayashi
The PAI-1 gene as a direct target of endothelial PAS domain protein-1 in adenocarcinoma A549 cells.
American journal of respiratory cell and molecular biology 2004;31(2):209-15.
2004: Norihiko Takeda; Koji Maemura; Yasushi Imai; Tomohiro Harada; Daiji Kawanami; Takefumi Nojiri; Ichiro Manabe; Ryozo Nagai
Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1.
Circulation research 2004;95(2):146-53.
2004: Yuichi Ikeda; Yasushi Imai; Hidetoshi Kumagai; Tetsuya Nosaka; Yoshihiro Morikawa; Tomoko Hisaoka; Ichiro Manabe; Koji Maemura; Takashi Nakaoka; Takeshi Imamura; Kohei Miyazono; Issei Komuro; Ryozo Nagai; Toshio Kitamura
Vasorin, a transforming growth factor beta-binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10732-7.
2004: Atsushi Tsuchida; Toshimasa Yamauchi; Yusuke Ito; Yusuke Hada; Toshiyuki Maki; Sato Takekawa; Junji Kamon; Masaki Kobayashi; Ryo Suzuki; Kazuo Hara; Naoto Kubota; Yasuo Terauchi; philippe froguel; Jun Nakae; Masato Kasuga; Domenico Accili; Kazuyuki Tobe; Kohjiro Ueki; Ryozo Nagai; Takashi Kadowaki
Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity.
The Journal of biological chemistry 2004;279(29):30817-22.
2004: Etsu Suzuki; Hiroshi Satonaka; Hiroaki Nishimatsu; Shigeyoshi Oba; Ryo Takeda; Masao Omata; Toshiro Fujita; Ryozo Nagai; Yasunobu Hirata
Myocyte enhancer factor 2 mediates vascular inflammation via the p38-dependent pathway.
Circulation research 2004;95(1):42-9.
2004: Nobukazu Ishizaka; Yuko Ishizaka; Ei-Ichi Toda; Hideki Hashimoto; Ryozo Nagai; Minoru Yamakado
Association between white blood cell count and carotid arteriosclerosis in Japanese smokers.
Atherosclerosis 2004;175(1):95-100.
2004: Satoshi Nishimura; So-ichiro Yasuda; Masayoshi Katoh; Kelly P Yamada; Hiroshi Yamashita; Yasutake Saeki; Kenji Sunagawa; Ryozo Nagai; Toshiaki Hisada; Seiryo Sugiura
Single cell mechanics of rat cardiomyocytes under isometric, unloaded, and physiologically loaded conditions.
American journal of physiology. Heart and circulatory physiology 2004;287(1):H196-202.
2004: Ryo Suzuki; Kazuyuki Tobe; Masashi Aoyama; Atsushi Inoue; Kentaro Sakamoto; Toshimasa Yamauchi; Junji Kamon; Naoto Kubota; Yasuo Terauchi; Hironobu Yoshimatsu; Munehide Matsuhisa; Shoichiro Nagasaka; Hitomi Ogata; Kumpei Tokuyama; Ryozo Nagai; Takashi Kadowaki
Both insulin signaling defects in the liver and obesity contribute to insulin resistance and cause diabetes in Irs2(-/-) mice.
The Journal of biological chemistry 2004;279(24):25039-49.
2004: Taisuke Jo; Taiji Nagata; Haruko Iida; Hiroyuki Imuta; Kuniaki Iwasawa; Ji Ma; Kei Hara; Masao Omata; Ryozo Nagai; Hajime Takizawa; Takashi Nagase; Toshiaki Nakajima
Voltage-gated sodium channel expressed in cultured human smooth muscle cells: involvement of SCN9A.
FEBS letters 2004;567(2-3):339-43.
2004: Masataka Sata; Hiroaki Nishimatsu; Jun-ichi Osuga; Kimie Tanaka; Nobukazu Ishizaka; Shun Ishibashi; Yasunobu Hirata; Ryozo Nagai
Statins augment collateral growth in response to ischemia but they do not promote cancer and atherosclerosis.
Hypertension 2004;43(6):1214-20.
2004: Naoya Yahagi; Hitoshi Shimano; Takashi Matsuzaka; Motohiro Sekiya; Yuho Najima; Sachiko Okazaki; Hiroaki Okazaki; Yoshiaki Tamura; Yoko Iizuka; Noriyuki Inoue; Yoshimi Nakagawa; Yoshinori Takeuchi; Ken Ohashi; Kenji Harada; Takanari Gotoda; Ryozo Nagai; Takashi Kadowaki; Shun Ishibashi; Jun-ichi Osuga; Nobuhiro Yamada
p53 involvement in the pathogenesis of fatty liver disease.
The Journal of biological chemistry 2004;279(20):20571-5.
2004: Hironosuke Sakamoto; Tetsuo Sakamaki; Tsugiyasu Kanda; Yoko Tsuchiya; Mahito Sato; Hiroko Sato; Yuko Oyama; Yoshie Sawada; Jun'ichi Tamura; Ryozo Nagai; Masahiko Kurabayashi
Vascular endothelial growth factor is an autocrine growth factor for cardiac myxoma cells.
Circulation journal : official journal of the Japanese Circulation Society 2004;68(5):488-93.
2004: Yoshinori Seko; Shuichi Fukuda; Ryozo Nagai
Serum levels of endostatin, vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in patients with acute myocardial infarction undergoing early reperfusion therapy.
Clinical science (London, England : 1979) 2004;106(5):439-42.
2004: Yoshinori Seko; Tsutomu Fujimura; Hikari Taka; Reiko Mineki; Kimie Murayama; Ryozo Nagai
Hypoxia followed by reoxygenation induces secretion of cyclophilin A from cultured rat cardiac myocytes.
Biochemical and biophysical research communications 2004;317(1):162-8.
2004: Pei Niu; Takayuki Shindo; Hiroshi Iwata; Satoshi Iimuro; Norifumi Takeda; Yuelan Zhang; Aya Ebihara; Yoshihiro Suematsu; Kenji Kangawa; Yasunobu Hirata; Ryozo Nagai
Protective effects of endogenous adrenomedullin on cardiac hypertrophy, fibrosis, and renal damage.
Circulation 2004;109(14):1789-94.
2004: Motohiro Sekiya; Jun-ichi Osuga; Hiroaki Okazaki; Naoya Yahagi; Kenji Harada; Wen-Jun Shen; Yoshiaki Tamura; Sachiko Tomita; Yoko Iizuka; Ken Ohashi; Mitsuyo Okazaki; Masataka Sata; Ryozo Nagai; Toshiro Fujita; Hitoshi Shimano; Fredric B Kraemer; Nobuhiro Yamada; Shun Ishibashi
Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice.
The Journal of biological chemistry 2004;279(15):15084-90.
2004: Ikuo Yokoyama; Yusuke Inoue; Toshiyuki Moritan; Kuni Ohtomo; Ryozo Nagai
Impaired myocardial vasodilatation during hyperaemic stress is improved by simvastatin but not by pravastatin in patients with hypercholesterolaemia.
European heart journal 2004;25(8):671-9.
2004: Hiroshi Satonaka; Etsu Suzuki; Hiroaki Nishimatsu; Shigeyoshi Oba; Ryo Takeda; Atsuo Goto; Masao Omata; Toshiro Fujita; Ryozo Nagai; Yasunobu Hirata
Calcineurin promotes the expression of monocyte chemoattractant protein-1 in vascular myocytes and mediates vascular inflammation.
Circulation research 2004;94(5):693-700.
2004: Yuichiro Saito; Masahiko Kurabayashi; Tetsuya Nakamura; Hiroyuki Morita; Ryozo Nagai
[Involvement of homocysteine in the pathogenesis of hypertension and hypertensive target-organ damage].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 3():211-5.
2004: Yuichiro Saito; Tetsuya Nakamura; Ryozo Nagai
[Klotho gene and hypertension].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 3():112-5.
2004: Doubun Hayashi; Yasushi Imai; Hiroyuki Morita; Hideo Fujita; Koshiro Monzen; Tomohiro Harada; Takefumi Nojiri; Tadashi Yamazaki; Tsutomu Yamazaki; Ryozo Nagai
Development of a pioneering clinical support system utilizing information technology.
Japanese heart journal 2004;45(2):315-24.
2004: Hiroki Kasai; Atsushi Yao; Tomomi Oyama; Hiroshi Hasegawa; Hiroshi Akazawa; Haruhiro Toko; Toshio Nagai; Koichiro Kinugawa; Osami Kohmoto; Kei Maruyama; Toshiyuki Takahashi; Ryozo Nagai; Atsushi Miyawaki; Issei Komuro
Direct measurement of Ca2+ concentration in the SR of living cardiac myocytes.
Biochemical and biophysical research communications 2004;314(4):1014-20.
2004: Daiji Kawanami; Koji Maemura; Norihiko Takeda; Tomohiro Harada; Takefumi Nojiri; Yasushi Imai; Ichiro Manabe; Kazunori Utsunomiya; Ryozo Nagai
Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine-endothelial cell interactions.
Biochemical and biophysical research communications 2004;314(2):415-9.
2004: Makoto Sonoda; Katsunori Yonekura; Ikuo Yokoyama; Katsu Takenaka; Ryozo Nagai; Teruhiko Aoyagi
Common carotid intima-media thickness is correlated with myocardial flow reserve in patients with coronary artery disease: a useful non-invasive indicator of coronary atherosclerosis.
International journal of cardiology 2004;93(2-3):131-6.
2004: Kenichi Aizawa; Toru Suzuki; Nanae Kada; Atsushi Ishihara; Keiko Kawai-Kowase; Takayoshi Matsumura; Kana Sasaki; Yoshiko Munemasa; Ichiro Manabe; Masahiko Kurabayashi; Tucker Collins; Ryozo Nagai
Regulation of platelet-derived growth factor-A chain by Krüppel-like factor 5: new pathway of cooperative activation with nuclear factor-kappaB.
The Journal of biological chemistry 2004;279(1):70-6.
2004: Nobukazu Ishizaka; Kan Saito; Eisei Noiri; Masataka Sata; Ichiro Mori; Minoru Ohno; Ryozo Nagai
Iron dextran causes renal iron deposition but not renal dysfunction in angiotensin II-treated and untreated rats.
Nephron. Physiology 2004;98(4):p107-13.
2004: Yukio Hiroi; Katsuhito Fujiu; Shuhei Komatsu; Makoto Sonoda; Yasunari Sakomura; Yasushi Imai; Yumi Oishi; Fumitaka Nakamura; Kohsuke Ajiki; Noriyuki Hayami; Yuji Murakawa; Minoru Ohno; Yasunobu Hirata; Kuni Ohtomo; Ryozo Nagai
Carvedilol therapy improved left ventricular function in a patient with arrhythmogenic right ventricular cardiomyopathy.
Japanese heart journal 2004;45(1):169-77.
2004: Yoshinori Seko; Kazuyuki Sugishita; Osamu Sato; Atsuhiko Takagi; Yusuke Tada; Hiroshi Matsuo; Hideo Yagita; Ko Okumura; Ryozo Nagai
Expression of costimulatory molecules (4-1BBL and Fas) and major histocompatibility class I chain-related A (MICA) in aortic tissue with Takayasu's arteritis.
Journal of vascular research 2004;41(1):84-90.
2004: Yuichiro Saito; Masahiko Kurabayashi; Ryozo Nagai
[klotho gene].
Nihon rinsho. Japanese journal of clinical medicine 2004;62(1):65-70.
2003: Toshimasa Yamauchi; Kazuo Hara; Naoto Kubota; Yasuo Terauchi; Kazuyuki Tobe; philippe froguel; Ryozo Nagai; Takashi Kadowaki
Dual roles of adiponectin/Acrp30 in vivo as an anti-diabetic and anti-atherogenic adipokine.
Current drug targets. Immune, endocrine and metabolic disorders 2003;3(4):243-54.
2003: Takefumi Nojiri; Hiroyuki Morita; Yasushi Imai; Koji Maemura; Minoru Ohno; Ken Ogasawara; Tadanori Aizawa; Akira Saito; Doubun Hayashi; Yasunobu Hirata; Takao Sugiyama; Tsutomu Yamazaki; Ryozo Nagai
Genetic variations of matrix metalloproteinase-1 and -3 promoter regions and their associations with susceptibility to myocardial infarction in Japanese.
International journal of cardiology 2003;92(2-3):181-6.
2003: Hiroshi Yamashita; Seiryo Sugiura; Hideo Fujita; So ichiro Yasuda; Ryozo Nagai; Yasutake Saeki; Kenji Sunagawa; Haruo Sugi
Myosin light chain isoforms modify force-generating ability of cardiac myosin by changing the kinetics of actin-myosin interaction.
Cardiovascular research 2003;60(3):580-8.
2003: Motohiro Sekiya; Naoya Yahagi; Takashi Matsuzaka; Yuho Najima; Masanori Nakakuki; Ryozo Nagai; Shun Ishibashi; Jun-ichi Osuga; Nobuhiro Yamada; Hitoshi Shimano
Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression.
Hepatology (Baltimore, Md.) 2003;38(6):1529-39.
2003: Saku Miyamoto; Toru Suzuki; Shinsuke Muto; Kenichi Aizawa; Akatsuki Kimura; Yoshiko Mizuno; Tomoko Nagino; Yasushi Imai; Naruhiko Adachi; Masami Horikoshi; Ryozo Nagai
Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domain.
Molecular and cellular biology 2003;23(23):8528-41.
2003: Toshiaki Nakajima; Ji Ma; Haruko Iida; Kuniaki Iwasawa; Taisuke Jo; Masao Omata; Ryozo Nagai
Inhibitory effects of carvedilol on calcium channels in vascular smooth muscle cells.
Japanese heart journal 2003;44(6):963-78.
2003: Takashi Kadowaki; Kazuo Hara; Toshimasa Yamauchi; Yasuo Terauchi; Kazuyuki Tobe; Ryozo Nagai
Molecular mechanism of insulin resistance and obesity.
Experimental biology and medicine (Maywood, N.J.) 2003;228(10):1111-7.
2003: Takeshi Natori; Masataka Sata; Miwa Washida; Yasunobu Hirata; Ryozo Nagai; Makuuchi Masatoshi
Nicotine enhances neovascularization and promotes tumor growth.
Molecules and cells 2003;16(2):143-6.
2003: Ryo Suzuki; Kazuyuki Tobe; Yasuo Terauchi; Kajuro Komeda; Naoto Kubota; Kazuhiro Eto; Toshimasa Yamauchi; Kousuke Azuma; Hideaki Kaneto; Takashi Taguchi; Teiichiro Koga; Michael S German; Hirotaka Watada; Ryuzo Kawamori; Christopher V E Wright; Yoshitaka Kajimoto; Satoshi Kimura; Ryozo Nagai; Takashi Kadowaki
Pdx1 expression in Irs2-deficient mouse beta-cells is regulated in a strain-dependent manner.
The Journal of biological chemistry 2003;278(44):43691-8.
2003: Kimie Tanaka; Masataka Sata; Yasunobu Hirata; Ryozo Nagai
Diverse contribution of bone marrow cells to neointimal hyperplasia after mechanical vascular injuries.
Circulation research 2003;93(8):783-90.
2003: Keiko Fukino; Masataka Sata; Yoshinori Seko; Yasunobu Hirata; Ryozo Nagai
Genetic background influences therapeutic effectiveness of VEGF.
Biochemical and biophysical research communications 2003;310(1):143-7.
2003: Hironori Waki; Toshimasa Yamauchi; Junji Kamon; Yusuke Ito; Shoko Uchida; Shunbun Kita; Kazuo Hara; Yusuke Hada; Francis Vasseur; philippe froguel; Satoshi Kimura; Ryozo Nagai; Takashi Kadowaki
Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin.
The Journal of biological chemistry 2003;278(41):40352-63.
2003: Ikuo Yokoyama; Yusuke Inoue; Toshiyuki Moritan; Kuni Ohtomo; Ryozo Nagai
Simple quantification of skeletal muscle glucose utilization by static 18F-FDG PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(10):1592-8.
2003: Kazuo Hara; Toshimasa Yamauchi; Naoto Kubota; Kazuyuki Tobe; Tsutomu Yamazaki; Ryozo Nagai; Takashi Kadowaki
[The role of PPARgamma in the onset of type 2 diabetes].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2003;122(4):317-24.
2003: Kan Saito; Nobukazu Ishizaka; Haruo Mitani; Minoru Ohno; Ryozo Nagai
Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation of klotho, an anti-aging gene, in rat.
FEBS letters 2003;551(1-3):58-62.
2003: Pei Niu; Takayuki Shindo; Hiroshi Iwata; Aya Ebihara; Yoshihiro Suematsu; Yuelan Zhang; Norifumi Takeda; Satoshi Iimuro; Yasunobu Hirata; Ryozo Nagai
Accelerated cardiac hypertrophy and renal damage induced by angiotensin II in adrenomedullin knockout mice.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(9):731-6.
2003: Masataka Sata; Kimie Tanaka; Nobukazu Ishizaka; Yasunobu Hirata; Ryozo Nagai
Absence of p53 leads to accelerated neointimal hyperplasia after vascular injury.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(9):1548-52.
2003: Tomohiro Harada; Toshiaki Nakajima; Naoshi Kobayakawa; Seiryo Sugiura; Ryozo Nagai
Slowly developing heart failure associated with hormonal disorder. Late-stage acromegalic cardiomyopathy.
Journal of cardiology 2003;42(2):95-8.
2003: Akio Saiura; Masataka Sata; Miwa Washida; Yasuhiko Sugawara; Yasunobu Hirata; Ryozo Nagai; Makuuchi Masatoshi
Little evidence for cell fusion between recipient and donor-derived cells.
The Journal of surgical research 2003;113(2):222-7.
2003: Toru Suzuki; Shinsuke Muto; Saku Miyamoto; Kenichi Aizawa; Masami Horikoshi; Ryozo Nagai
Functional interaction of the DNA-binding transcription factor Sp1 through its DNA-binding domain with the histone chaperone TAF-I.
The Journal of biological chemistry 2003;278(31):28758-64.
2003: So-ichiro Yasuda; Seiryo Sugiura; Hiroshi Yamashita; Satoshi Nishimura; Yasutake Saeki; Shin-ichi Momomura; Kaoru Katoh; Ryozo Nagai; Haruo Sugi
Unloaded shortening increases peak of Ca2+ transients but accelerates their decay in rat single cardiac myocytes.
American journal of physiology. Heart and circulatory physiology 2003;285(2):H470-5.
2003: Naoya Yahagi; Hitoshi Shimano; Takashi Matsuzaka; Yuho Najima; Motohiro Sekiya; Yoshimi Nakagawa; Tomohiro Ide; Sachiko Tomita; Hiroaki Okazaki; Yoshiaki Tamura; Yoko Iizuka; Ken Ohashi; Takanari Gotoda; Ryozo Nagai; Satoshi Kimura; Shun Ishibashi; Jun-ichi Osuga; Nobuhiro Yamada
p53 Activation in adipocytes of obese mice.
The Journal of biological chemistry 2003;278(28):25395-400.
2003: Tomohiro Harada; Yasushi Imai; Takefumi Nojiri; Hiroyuki Morita; Doubun Hayashi; Koji Maemura; Keiko Fukino; Daiji Kawanami; Go Nishimura; Kensuke Tsushima; Koshiro Monzen; Tadashi Yamazaki; Satoshi Mitsuyama; Takahiko Shintani; Narimasa Watanabe; Kumiko Seto; Takao Sugiyama; Fumitaka Nakamura; Minoru Ohno; Yasunobu Hirata; Tsutomu Yamazaki; Ryozo Nagai
A common Ile 823 Met variant of ATP-binding cassette transporter A1 gene (ABCA1) alters high density lipoprotein cholesterol level in Japanese population.
Atherosclerosis 2003;169(1):105-12.
2003: Minami Abe; Masataka Sata; Hiroaki Nishimatsu; Daisuke Nagata; Etsu Suzuki; Yasuo Terauchi; Takashi Kadowaki; Naoto Minamino; Kenji Kangawa; Hisayuki Matsuo; Yasunobu Hirata; Ryozo Nagai
Adrenomedullin augments collateral development in response to acute ischemia.
Biochemical and biophysical research communications 2003;306(1):10-5.
2003: Toshiro Ogata; Masahiko Kurabayashi; Toshitaka Maeno; Ken-ichi Sekiguchi; Yo-ichi Hoshino; Susumu Ishikawa; Hiroyuki Takei; Ryozo Nagai; Yasuo Morishita
Angiogenesis inhibitor TNP-470 (AGM-1470) suppresses vascular smooth muscle cell proliferation after balloon injury in rats.
The Journal of surgical research 2003;112(2):117-21.
2003: Toshio Nagai; Mariko Tanaka-Ishikawa; Ryuichi Aikawa; Hisamitsu Ishihara; Weidung Zhu; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Cdc42 plays a critical role in assembly of sarcomere units in series of cardiac myocytes.
Biochemical and biophysical research communications 2003;305(4):806-10.
2003: Toshimasa Yamauchi; Junji Kamon; Yusuke Ito; Atsushi Tsuchida; Takehiko Yokomizo; Shunbun Kita; Takuya Sugiyama; Makoto Miyagishi; Kazuo Hara; Masaki Tsunoda; Koji Murakami; Toshiaki Ohteki; Shoko Uchida; Sato Takekawa; Hironori Waki; Nelson H Tsuno; Yoichi Shibata; Yasuo Terauchi; philippe froguel; Kazuyuki Tobe; Shigeo Koyasu; Kazunari Taira; Toshio Kitamura; Takao Shimizu; Ryozo Nagai; Takashi Kadowaki
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.
Nature 2003;423(6941):762-9.
2003: Yasushi Fukushima; Takayuki Shindo; Motonobu Anai; Toshihito Saitoh; Yuhui Wang; Midori Fujishiro; Yoshio Ohashi; Takehide Ogihara; Kouichi Inukai; Hiraku Ono; Hideyuki Sakoda; Yukiko Kurihara; Miho Honda; Nobuhiro Shojima; Harumi Fukushima; Yukiko Haraikawa-Onishi; Hideki Katagiri; Yasuhito Shimizu; Masao Ichinose; Takashi Ishikawa; Masao Omata; Ryozo Nagai; Hiroki Kurihara; Tomoichiro Asano
Structural and functional characterization of gastric mucosa and central nervous system in histamine H2 receptor-null mice.
European journal of pharmacology 2003;468(1):47-58.
2003: Tomohiro Harada; Hiroyuki Morita; Yasushi Imai; Doubun Hayashi; Norihiko Takeda; Koji Maemura; Yoshio Yazaki; Ryozo Nagai
Deficiency of protein S-mediated familial venous thrombophilia--a case report.
Angiology 2003;54(3):377-81.
2003: Toru Suzuki; Masamichi Nishida; Satoru Futami; Keiko Fukino; Toshihiro Amaki; Kenichi Aizawa; Shigeru Chiba; Hisamaru Hirai; Kazuhiko Maekawa; Ryozo Nagai
Neoendothelialization after peripheral blood stem cell transplantation in humans: a case report of a Tokaimura nuclear accident victim.
Cardiovascular research 2003;58(2):487-92.
2003: Koichiro Kinugawa; Toshiyuki Takahashi; Ryozo Nagai
[Treatment for diastolic failure].
Nihon rinsho. Japanese journal of clinical medicine 2003;61(5):857-61.
2003: Ichiro Manabe; Ryozo Nagai
Regulation of smooth muscle phenotype.
Current atherosclerosis reports 2003;5(3):214-22.
2003: Yasuo Terauchi; Junji Matsui; Ryo Suzuki; Naoto Kubota; Kajuro Komeda; Shinichi Aizawa; Kazuhiro Eto; Satoshi Kimura; Ryozo Nagai; Kazuyuki Tobe; Gustav E Lienhard; Takashi Kadowaki
Impact of genetic background and ablation of insulin receptor substrate (IRS)-3 on IRS-2 knock-out mice.
The Journal of biological chemistry 2003;278(16):14284-90.
2003: Yoshiaki Tamura; Hideki Adachi; Jun-ichi Osuga; Ken Ohashi; Naoya Yahagi; Motohiro Sekiya; Hiroaki Okazaki; Sachiko Tomita; Yoko Iizuka; Hitoshi Shimano; Ryozo Nagai; Satoshi Kimura; Masafumi Tsujimoto; Shun Ishibashi
FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.
The Journal of biological chemistry 2003;278(15):12613-7.
2003: Yasushi Imai; Ryozo Nagai
[New biochemical and genetic risk factors for coronary artery diseases].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 4():775-80.
2003: Nanae Kada; Hiroshi Nishimura; Ryozo Nagai
[Biochemical diagnosis, molecular genetics method].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 4():418-24.
2003: Ji Ma; Toshiaki Nakajima; Haruko Iida; Kuniaki Iwasawa; Kuniko Terasawa; Hitoshi Oonuma; Taisuke Jo; Toshihiro Morita; Hiroyuki Imuta; Jun ichi Suzuki; Ken Hirose; Yukichi Okuda; Nobuhiko Yamada; Ryozo Nagai; Masao Omata
Inhibitory effects of ursodeoxycholic acid on the induction of nitric oxide synthase in vascular smooth muscle cells.
European journal of pharmacology 2003;464(2-3):79-86.
2003: Ryozo Nagai
[Cardiovascular research in the era of genome medicine and EBM].
Rinsho byori. The Japanese journal of clinical pathology 2003;51(3):208-13.
2003: Masatoshi Suzuki; Naoyuki Iso-o; Satoshi Takeshita; Kazuhisa Tsukamoto; Ichiro Mori; Tomohide Sato; Minoru Ohno; Ryozo Nagai; Nobukazu Ishizaka
Facilitated angiogenesis induced by heme oxygenase-1 gene transfer in a rat model of hindlimb ischemia.
Biochemical and biophysical research communications 2003;302(1):138-43.
2003: Hiroaki Nishimatsu; Yasunobu Hirata; Takayuki Shindo; Hiroki Kurihara; Etsu Suzuki; Masataka Sata; Hiroshi Satonaka; Ryo Takeda; Daisuke Nagata; Masao Kakoki; Hiroshi Hayakawa; Kenji Kangawa; Hisayuki Matsuo; Tadaichi Kitamura; Ryozo Nagai
Endothelial responses of the aorta from adrenomedullin transgenic mice and knockout mice.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26 Suppl():S79-84.
2003: Nobukazu Ishizaka; Yuko Ishizaka; Eiko Takahashi; Tadao Unuma; Ei-ichi Tooda; Ryozo Nagai; Masako Togo; Kazuhisa Tsukamoto; Hideki Hashimoto; Minoru Yamakado
Association between insulin resistance and carotid arteriosclerosis in subjects with normal fasting glucose and normal glucose tolerance.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(2):295-301.
2003: Toshimasa Yamauchi; Junji Kamon; Hironori Waki; Yasushi Imai; Nobuhiro Shimozawa; Kyouji Hioki; Shoko Uchida; Yusuke Ito; Keisuke Takakuwa; Junji Matsui; Makoto Takata; Kazuhiro Eto; Yasuo Terauchi; Kajuro Komeda; Masaki Tsunoda; Koji Murakami; Yasuyuki Ohnishi; Takeshi Naitoh; Kenichi Yamamura; Yoshito Ueyama; philippe froguel; Satoshi Kimura; Ryozo Nagai; Takashi Kadowaki
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis.
The Journal of biological chemistry 2003;278(4):2461-8.
2003: Seiryo Sugiura; So-ichiro Yasuda; Hiroshi Yamashita; Kaoru Kato; Yasutake Saeki; Hiroko Kaneko; Yoshihisa Suda; Ryozo Nagai; Haruo Sugi
Measurement of force developed by a single cardiac myocyte using novel carbon fibers.
Advances in experimental medicine and biology 2003;538():381-6; discussion 386-7.
2003: Ryozo Nagai; Takayuki Shindo; Ichiro Manabe; Toru Suzuki; Masahiko Kurabayashi
KLF5/BTEB2, a Krüppel-like zinc-finger type transcription factor, mediates both smooth muscle cell activation and cardiac hypertrophy.
Advances in experimental medicine and biology 2003;538():57-65; discussion 66.
2003: Yasushi Fukushima; Takashi Ishikawa; Toshihito Saitoh; Keisuke Tateishi; Takehide Ogihara; Midori Fujishiro; Nobuhiro Shojima; Miho Honda; Akifumi Kushiyama; Motonobu Anai; Hideyuki Sakoda; Hiraku Ono; Yukiko Onishi; Hiroko Otsuka; Hideki Katagiri; Ryozo Nagai; Masao Omata; Tomoichiro Asano
Extremely early onset of ranitidine action on human histamine H2 receptors expressed in HEK293 cells.
Digestion 2003;68(2-3):145-52.
2003: Hironosuke Sakamoto; Tetsuo Sakamaki; Tsugiyasu Kanda; Yo-ichi Hoshino; Yoshie Sawada; Mahito Sato; Hiroko Sato; Yuko Oyama; Akihiko Nakano; Shin-ichi Takase; Akira Hasegawa; Ryozo Nagai; Masahiko Kurabayashi
Smooth muscle cell outgrowth from coronary atherectomy specimens in vitro is associated with less time to restenosis and expression of a key Transcription factor KLF5/BTEB2.
Cardiology 2003;100(2):80-5.
2003: Kazuo Hara; Kazuhiko Ohe; Takashi Kadowaki; Naoya Kato; Yasushi Imai; Katsushi Tokunaga; Ryozo Nagai; Masao Omata
Establishment of a method of anonymization of DNA samples in genetic research.
Journal of human genetics 2003;48(6):327-30.
2003: Yukio Hiroi; Tomoko Nakao; Naoyuki Tsuchiya; Norihiko Takeda; Koji Maemura; Fumitaka Nakamura; Minoru Ohno; Yasunobu Hirata; Ryozo Nagai
Exacerbation of Lambert-Eaton myasthenic syndrome caused by an L-type Ca2+ channel antagonist.
Japanese heart journal 2003;44(1):139-44.
2003: Yuji Murakawa; Takeshi Yamashita; Kohsuke Ajiki; Noriyuki Hayami; Masao Omata; Ryozo Nagai
Effect of cervical vagal nerve stimulation on defibrillation energy: a possible adjunct to efficient defibrillation.
Japanese heart journal 2003;44(1):91-100.
2003: Kazuyuki Tobe; Shohji Asai; Koozi Matuoka; Tadashi Yamamoto; Kazuhiro Chida; Yasushi Kaburagi; Yasuo Akanuma; Toshio Kuroki; Tadaomi Takenawa; Satoshi Kimura; Ryozo Nagai; Takashi Kadowaki
Cytoskeletal reorganization induced by insulin: involvement of Grb2/Ash, Ras and phosphatidylinositol 3-kinase signalling.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(1):29-40.
2003: Atsushi Yao; Osami Kohmoto; Tomomi Oyama; Yasuyuki Sugishita; Tatsuya Shimizu; Kazumasa Harada; Hiroshi Matsui; Issei Komuro; Ryozo Nagai; Hiroshi Matsuo; Takashi Serizawa; Takashi Maruyama; Toshiyuki Takahashi
Characteristic effects of alpha1-beta1,2-adrenergic blocking agent, carvedilol, on [Ca2+]i in ventricular myocytes compared with those of timolol and atenolol.
Circulation journal : official journal of the Japanese Circulation Society 2003;67(1):83-90.
2003: Yuko Ishizaka; Nobukazu Ishizaka; Eiko Takahashi; Tadao Unuma; Ei-ichi Tooda; Hideki Hashimoto; Ryozo Nagai; Minoru Yamakado
Association between hepatitis C virus core protein and carotid atherosclerosis.
Circulation journal : official journal of the Japanese Circulation Society 2003;67(1):26-30.
2002: Ichiro Manabe; Takayuki Shindo; Ryozo Nagai
Gene expression in fibroblasts and fibrosis: involvement in cardiac hypertrophy.
Circulation research 2002;91(12):1103-13.
2002: Kuniko Terasawa; Toshiaki Nakajima; Haruko Iida; Kuniaki Iwasawa; Hitoshi Oonuma; Taisuke Jo; Toshihiro Morita; Fumitaka Nakamura; Yoshiharu Fujimori; Teruhiko Toyo-Oka; Ryozo Nagai
Nonselective cation currents regulate membrane potential of rabbit coronary arterial cell: modulation by lysophosphatidylcholine.
Circulation 2002;106(24):3111-9.
2002: Koshiro Monzen; Weidong Zhu; Hiroki Kasai; Yukio Hiroi; Toru Hosoda; Hiroshi Akazawa; Yunzeng Zou; Doubun Hayashi; Tsutomu Yamazaki; Ryozo Nagai; Issei Komuro
Dual effects of the homeobox transcription factor Csx/Nkx2-5 on cardiomyocytes.
Biochemical and biophysical research communications 2002;298(4):493-500.
2002: Tomoko Aoki-Nagase; Takashi Nagase; Yoshio Oh-hashi; Takayuki Shindo; Yukiko Kurihara; Yasuhiro Yamaguchi; Hiroshi Yamamoto; Tetsuji Tomita; Eijiro Ohga; Ryozo Nagai; Hiroki Kurihara; Yasuyoshi Ouchi
Attenuation of antigen-induced airway hyperresponsiveness in CGRP-deficient mice.
American journal of physiology. Lung cellular and molecular physiology 2002;283(5):L963-70.
2002: Toshimasa Yamauchi; Junji Kamon; Yasuhiko Minokoshi; Yusuke Ito; Hironori Waki; Shoko Uchida; Shigeo Yamashita; Mitsuhiko Noda; Shunbun Kita; Keisuke Ueki; Kazuhiro Eto; Yasuo Akanuma; philippe froguel; Fabienne Foufelle; pascal ferre; David Carling; Satoshi Kimura; Ryozo Nagai; B B Kahn; Takashi Kadowaki
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase.
Nature medicine 2002;8(11):1288-95.
2002: Takeshi Natori; Masataka Sata; Miwa Washida; Yasunobu Hirata; Ryozo Nagai; Makuuchi Masatoshi
G-CSF stimulates angiogenesis and promotes tumor growth: potential contribution of bone marrow-derived endothelial progenitor cells.
Biochemical and biophysical research communications 2002;297(4):1058-61.
2002: Nobukazu Ishizaka; Haruo Mitani; Ryozo Nagai
[Angiotensin II regulates klotho gene expression].
Nihon rinsho. Japanese journal of clinical medicine 2002;60(10):1935-9.
2002: Hideaki Kaneda; Minoru Ohno; Junichi Taguchi; Masako Togo; Hideki Hashimoto; Ken Ogasawara; Tadanori Aizawa; Nobukazu Ishizaka; Ryozo Nagai
Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(10):1680-5.
2002: Nobukazu Ishizaka; Kan Saito; Haruo Mitani; Ieharu Yamazaki; Masataka Sata; Shin-ichi Usui; Ichiro Mori; Minoru Ohno; Ryozo Nagai
Iron overload augments angiotensin II-induced cardiac fibrosis and promotes neointima formation.
Circulation 2002;106(14):1840-6.
2002: Etsu Suzuki; Hiroaki Nishimatsu; Daisuke Nagata; Hiroshi Satonaka; Atsuo Goto; Masao Omata; Toshiro Fujita; Ryozo Nagai; Yasunobu Hirata
Constitutive activation of proto-oncogen protein p21 induces cell cycle arrest in the G1 phase in contact-inhibited vascular endothelial cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(5):773-8.
2002: Mariko Kamemori; Yoshio Ohyama; Masahiko Kurabayashi; Katumasa Takahashi; Ryozo Nagai; Nobuhiko Furuya
Expression of Klotho protein in the inner ear.
Hearing research 2002;171(1-2):103-110.
2002: Hiroaki Okazaki; Jun-ichi Osuga; Kazuhisa Tsukamoto; Noriko Isoo; Tetsuya Kitamine; Yoshiaki Tamura; Sachiko Tomita; Motohiro Sekiya; Naoya Yahagi; Yoko Iizuka; Ken Ohashi; Kenji Harada; Takanari Gotoda; Hitoshi Shimano; Satoshi Kimura; Ryozo Nagai; Nobuhiro Yamada; Shun Ishibashi
Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase.
The Journal of biological chemistry 2002;277(35):31893-9.
2002: Koshiro Monzen; Ryozo Nagai; Issei Komuro
A role for bone morphogenetic protein signaling in cardiomyocyte differentiation.
Trends in cardiovascular medicine 2002;12(6):263-9.
2002: Yasushi Imai; Takayuki Shindo; Koji Maemura; Masataka Sata; Yuichiro Saito; Yukiko Kurihara; Masahiro Akishita; Jun-ichi Osuga; Shun Ishibashi; Kazuyuki Tobe; Hiroyuki Morita; Yoshio Oh-hashi; Toru Suzuki; Hiromitsu Maekawa; Kenji Kangawa; Naoto Minamino; Yoshio Yazaki; Ryozo Nagai; Hiroki Kurihara
Resistance to neointimal hyperplasia and fatty streak formation in mice with adrenomedullin overexpression.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(8):1310-5.
2002: Masataka Sata; Akihiro Takahashi; Kimie Tanaka; Miwa Washida; Nobukazu Ishizaka; Junya Ako; Masao Yoshizumi; Yasuyoshi Ouchi; Takahiro Taniguchi; Yasunobu Hirata; Mitsuhiro Yokoyama; Ryozo Nagai; Kenneth Walsh
Mouse genetic evidence that tranilast reduces smooth muscle cell hyperplasia via a p21(WAF1)-dependent pathway.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(8):1305-9.
2002: Takayuki Shindo; Ichiro Manabe; Yasushi Fukushima; Kazuyuki Tobe; Kenichi Aizawa; Saku Miyamoto; Keiko Kawai-Kowase; Nobuo Moriyama; Yasushi Imai; Hayato Kawakami; Hiroaki Nishimatsu; Takashi Ishikawa; Toru Suzuki; Hiroyuki Morita; Koji Maemura; Masataka Sata; Yasunobu Hirata; Masayuki Komukai; Hiroyuki Kagechika; Takashi Kadowaki; Masahiko Kurabayashi; Ryozo Nagai
Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.
Nature medicine 2002;8(8):856-63.
2002: Naoto Kubota; Yasuo Terauchi; Toshimasa Yamauchi; Tetsuya Kubota; Masao Moroi; Junji Matsui; Kazuhiro Eto; Tokuyuki Yamashita; Junji Kamon; Hidemi Satoh; Wataru Yano; philippe froguel; Ryozo Nagai; Satoshi Kimura; Takashi Kadowaki; Tetsuo Noda
Disruption of adiponectin causes insulin resistance and neointimal formation.
The Journal of biological chemistry 2002;277(29):25863-6.
2002: Koichi Inoue; Koichi Matsuda; Makoto Itoh; Hiroshi Kawaguchi; Hitonobu Tomoike; Teruhiko Aoyagi; Ryozo Nagai; Masatsugu Hori; Yusuke Nakamura; Toshihiro Tanaka
Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
Human molecular genetics 2002;11(15):1775-84.
2002: Satoru Muto; Atsu Aiba; Yuichirou Saito; Kazuki Nakao; Kenji Nakamura; Kyoichi Tomita; Tadaichi Kitamura; Masahiko Kurabayashi; Ryozo Nagai; Eiji Higashihara; Peter C Harris; Motoya Katsuki; Shigeo Horie
Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant.
Human molecular genetics 2002;11(15):1731-42.
2002: Haruhiro Toko; Weidong Zhu; Eiki Takimoto; Ichiro Shiojima; Yukio Hiroi; Yunzeng Zou; Toru Oka; Hiroshi Akazawa; Miho Mizukami; Masaya Sakamoto; Fumio Terasaki; Yasushi Kitaura; Hiroyuki Takano; Toshio Nagai; Ryozo Nagai; Issei Komuro
Csx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart.
The Journal of biological chemistry 2002;277(27):24735-43.
2002: Masataka Sata; Yasunobu Hirata; Ryozo Nagai
Role of Fas/Fas ligand interaction in ischemia-induced collateral vessel growth.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(4):577-82.
2002: Toru Suzuki; Hiroaki Kohno; Akira Hasegawa; Shunichi Toshima; Toshihiro Amaki; Masahiko Kurabayashi; Ryozo Nagai; Toru Suzuki; Toshihiro Amaki; Ryozo Nagai; Akira Hasegawa; Shunichi Toshima; Masa-hiko Kurabayashi; Kazuyuki Shimada; Haruo Nakamura; Tamio Teramoto; Hiroshi Yamaguchi; Shin-ichiro Nishiyama; Hakuo Takahashi; Ichiro Michishita; Zinpei Sugano; Keiko Konoshi
Diagnostic implications of circulating oxidized low density lipoprotein levels as a biochemical risk marker of coronary artery disease.
Clinical biochemistry 2002;35(5):347-53.
2002: Tetsuya Nakamura; Yuichiro Saito; Yoshio Ohyama; Hiroaki Masuda; Hiroyuki Sumino; Makoto Kuro-o; Youichi Nabeshima; Ryozo Nagai; Masahiko Kurabayashi
Production of nitric oxide, but not prostacyclin, is reduced in klotho mice.
Japanese journal of pharmacology 2002;89(2):149-56.
2002: Yuichi Ikeda; Yukio Hiroi; Toru Hosoda; Toshinori Utsunomiya; Shuzo Matsuo; Tsuyoshi Ito; Jun-ichi Inoue; Tetsuya Sumiyoshi; Hiroyuki Takano; Ryozo Nagai; Issei Komuro
Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease.
Circulation journal : official journal of the Japanese Circulation Society 2002;66(6):561-3.
2002: Kou-ichi Tomaru Ki; Masashi Arai; Tomoyuki Yokoyama; Yasushi Aihara; Ken-ichi Sekiguchi Ki; Toru Tanaka; Ryozo Nagai; Masahiko Kurabayashi
Transcriptional activation of the BNP gene by lipopolysaccharide is mediated through GATA elements in neonatal rat cardiac myocytes.
Journal of molecular and cellular cardiology 2002;34(6):649-59.
2002: Naoya Yahagi; Hitoshi Shimano; Alyssa H Hasty; Takashi Matsuzaka; Tomohiro Ide; Tomohiro Yoshikawa; Michiyo Amemiya-Kudo; Sachiko Tomita; Hiroaki Okazaki; Yoshiaki Tamura; Yoko Iizuka; Ken Ohashi; Jun-ichi Osuga; Kenji Harada; Takanari Gotoda; Ryozo Nagai; Shun Ishibashi; Nobuhiro Yamada
Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.
The Journal of biological chemistry 2002;277(22):19353-7.
2002: Ryuichi Aikawa; Yuko Nitta-Komatsubara; Sumiyo Kudoh; Hiroyuki Takano; Toshio Nagai; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Reactive oxygen species induce cardiomyocyte apoptosis partly through TNF-alpha.
Cytokine 2002;18(4):179-83.
2002: Etsu Suzuki; Hiroaki Nishimatsu; Hiroshi Satonaka; Kenneth Walsh; Atsuo Goto; Masao Omata; Toshiro Fujita; Ryozo Nagai; Yasunobu Hirata
Angiotensin II induces myocyte enhancer factor 2- and calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes.
Circulation research 2002;90(9):1004-11.
2002: Yoshinori Seko; Shigeru Ishiyama; Toshiro Nishikawa; Takeshi Kasajima; Michiaki Hiroe; Shin Suzuki; Sugao Ishiwata; Sachio Kawai; Yuetsu Tanaka; Miyuki Azuma; Tetsuji Kobata; Hideo Yagita; Ko Okumura; Ryozo Nagai
Expression of tumor necrosis factor ligand superfamily costimulatory molecules CD27L, CD30L, OX40L and 4-1BBL in the heart of patients with acute myocarditis and dilated cardiomyopathy.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2002;11(3):166-70.
2002: Keiko Fukino; Toru Suzuki; Yuichiro Saito; Takayuki Shindo; Toshihiro Amaki; Masahiko Kurabayashi; Ryozo Nagai
Regulation of angiogenesis by the aging suppressor gene klotho.
Biochemical and biophysical research communications 2002;293(1):332-7.
2002: Yoshinori Seko; Nobuhiko Kayagaki; Ken-ichiro Seino; Hideo Yagita; Ko Okumura; Ryozo Nagai
Role of Fas/FasL pathway in the activation of infiltrating cells in murine acute myocarditis caused by Coxsackievirus B3.
Journal of the American College of Cardiology 2002;39(8):1399-403.
2002: Hiroaki Nishimatsu; Yasunobu Hirata; Takayuki Shindo; Hiroki Kurihara; Masao Kakoki; Daisuke Nagata; Hiroshi Hayakawa; Hiroshi Satonaka; Masataka Sata; Arinobu Tojo; Etsu Suzuki; Kenji Kangawa; Hisayuki Matsuo; Tadaichi Kitamura; Ryozo Nagai
Role of endogenous adrenomedullin in the regulation of vascular tone and ischemic renal injury: studies on transgenic/knockout mice of adrenomedullin gene.
Circulation research 2002;90(6):657-63.
2002: Yuji Murakawa; Takeshi Yamashita; Kohsuke Ajiki; Noriyuki Hayami; Ei-Ichi Fukui; Yuji Kasaoka; Masao Omata; Ryozo Nagai
Site of the arrhythmogenic focus and cardiac vulnerability to ventricular fibrillation.
Pacing and clinical electrophysiology : PACE 2002;25(4 Pt 1):446-56.
2002: Haruo Mitani; Nobukazu Ishizaka; Tadanori Aizawa; Minoru Ohno; Shin-ichi Usui; Toru Suzuki; Toshihiro Amaki; Ichiro Mori; Yasushi Nakamura; Misako Sato; Masaomi Nangaku; Yasunobu Hirata; Ryozo Nagai
In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage.
Hypertension 2002;39(4):838-43.
2002: Naobumi Mise; Kenjiro Kimura; Masahiko Kurabayashi; Ryozo Nagai; Toshihiro Okuda; Shigeyoshi Ohba; Naoe Suzuki; Kazuhisa Miyashita; Atsuko Kamijo; Arinobu Tojo; Atsuo Goto; Masao Omata
Angiotensin II enhances glomerular expression of a nonmuscle myosin heavy chain, SMemb, with extracellular matrix accumulation.
Nephron 2002;90(4):477-83.
2002: Masataka Sata; Akio Saiura; Atsushi Kunisato; Arinobu Tojo; Seiji Okada; Takeshi Tokuhisa; Hisamaru Hirai; Makuuchi Masatoshi; Yasunobu Hirata; Ryozo Nagai
Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis.
Nature medicine 2002;8(4):403-9.
2002: Taeko Tsuji; Jun-ichi Suzuki; Ryoichi Shimamoto; Tadashi Yamazaki; Toshiaki Nakajima; Ryozo Nagai; Shuhei Komatsu; Kuni Ohtomo; Teruhiko Toyo-Oka; Masao Omata
Vector analysis of the wall shear rate at the human aortoiliac bifurcation using cine MR velocity mapping.
AJR. American journal of roentgenology 2002;178(4):995-9.
2002: Atai Watanabe; Hiroyoshi Kanai; Masashi Arai; Kenichi Sekiguchi; Tsuyoshi Uchiyama; Ryozo Nagai; Masahiko Kurabayashi
Retinoids induce the PAI-1 gene expression through tyrosine kinase-dependent pathways in vascular smooth muscle cells.
Journal of cardiovascular pharmacology 2002;39(4):503-12.
2002: Norifumi Takeda; Ikuo Yokoyama; Yukio Hiroi; M Sakata; T Harada; Fumitaka Nakamura; Yuji Murakawa; Ryozo Nagai
Positron emission tomography predicted recovery of complete A-V nodal dysfunction in a patient with cardiac sarcoidosis.
Circulation 2002;105(9):1144-5.
2002: Nobukazu Ishizaka; Yuko Ishizaka; Eiko Takahashi; Ei-ichi Toda Ei; Hideki Hashimoto; Minoru Ohno; Ryozo Nagai; Minoru Yamakado
Increased prevalence of carotid atherosclerosis in hepatitis B virus carriers.
Circulation 2002;105(9):1028-30.
2002: Nobukazu Ishizaka; Yuko Ishizaka; Eiko Takahashi; Ei-ichi Tooda; Hideki Hashimoto; Ryozo Nagai; Minoru Yamakado
Serum calcium concentration and carotid artery plaque: a population-based study.
Journal of cardiology 2002;39(3):151-7.
2002: Eiki Takimoto; Atsushi Yao; Haruhiro Toko; Hiroyuki Takano; Masaki Shimoyama; Makoto Sonoda; Koji Wakimoto; Toshiyuki Takahashi; Hiroshi Akazawa; Miho Mizukami; Toshio Nagai; Ryozo Nagai; Issei Komuro
Sodium calcium exchanger plays a key role in alteration of cardiac function in response to pressure overload.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(3):373-8.
2002: Hitoshi Oonuma; Kuniaki Iwasawa; Haruko Iida; Taiji Nagata; Hiroyuki Imuta; Yutaka Morita; Kazuhiko Yamamoto; Ryozo Nagai; Masao Omata; Toshiaki Nakajima
Inward rectifier K(+) current in human bronchial smooth muscle cells: inhibition with antisense oligonucleotides targeted to Kir2.1 mRNA.
American journal of respiratory cell and molecular biology 2002;26(3):371-9.
2002: Yuko Oyama; Nobuhiro Akuzawa; Ryozo Nagai; Masahiko Kurabayashi
PPARgamma ligand inhibits osteopontin gene expression through interference with binding of nuclear factors to A/T-rich sequence in THP-1 cells.
Circulation research 2002;90(3):348-55.
2002: Takayuki Shindo; Hiroki Kurihara; Koji Maemura; Yukiko Kurihara; Otoya Ueda; Hiramitsu Suzuki; Tomoyuki Kuwaki; Kihwan Ju; Y Wang; Aya Ebihara; Hiroaki Nishimatsu; Nobuo Moriyama; M Fukuda; Y Akimoto; H Hirano; Hiroyuki Morita; Mamoru Kumada; Yoshio Yazaki; Ryozo Nagai; K Kimura
Renal damage and salt-dependent hypertension in aged transgenic mice overexpressing endothelin-1.
Journal of molecular medicine (Berlin, Germany) 2002;80(2):105-16.
2002: Ryuichi Aikawa; Toshio Nagai; Sumiyo Kudoh; Yunzeng Zou; Mariko Tanaka; Masahito Tamura; Hiroshi Akazawa; Hiroyuki Takano; Ryozo Nagai; Issei Komuro
Integrins play a critical role in mechanical stress-induced p38 MAPK activation.
Hypertension 2002;39(2):233-8.
2002: Toshimasa Yamauchi; Yuichi Oike; Junji Kamon; Hironori Waki; Kajuro Komeda; Atsushi Tsuchida; Yukari Date; Meng Xian Li; Hiroshi Miki; Yasuo Akanuma; Ryozo Nagai; Satoshi Kimura; Takeyori Saheki; Masamitsu Nakazato; Takeshi Naitoh; Kenichi Yamamura; Takashi Kadowaki
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice.
Nature genetics 2002;30(2):221-6.
2002: Kazuo Hara; Philippe Boutin; Yasumichi Mori; Kazuyuki Tobe; Christian Dina; Kazuki Yasuda; Toshimasa Yamauchi; Shuichi Otabe; Terumasa Okada; Kazuhiro Eto; Hiroko Kadowaki; Ryoko Hagura; Yasuo Akanuma; Yoshio Yazaki; Ryozo Nagai; Matsuo Taniyama; Koichi Matsubara; Madoka Yoda; Yasuko Nakano; Motowo Tomita; Satoshi Kimura; Chikako Ito; philippe froguel; Takashi Kadowaki
Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.
Diabetes 2002;51(2):536-40.
2002: Toshitaka Maeno; Toru Tanaka; Yoshichika Sando; Tatsuo Suga; Yuri Maeno; Junichi Nakagawa; Tatsuya Hosono; Mahito Sato; Hideo Akiyama; Shoji Kishi; Ryozo Nagai; Masahiko Kurabayashi
Stimulation of vascular endothelial growth factor gene transcription by all trans retinoic acid through Sp1 and Sp3 sites in human bronchioloalveolar carcinoma cells.
American journal of respiratory cell and molecular biology 2002;26(2):246-53.
2002: Nobukazu Ishizaka; Yuko Ishizaka; Eiko Takahashi; Ei-ichi Tooda; Hideki Hashimoto; Ryozo Nagai; Minoru Yamakado
Association between hepatitis C virus seropositivity, carotid-artery plaque, and intima-media thickening.
Lancet 2002;359(9301):133-5.
2002: Hiroyasu Iwasa; Masahiko Kurabayashi; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Twenty single-nucleotide polymorphisms in four genes encoding cardiac ion channels.
Journal of human genetics 2002;47(4):208-12.
2002: Yunzeng Zou; Tsutomu Yamazaki; Keiichi Nakagawa; Haruyasu Yamada; Norio Iriguchi; Haruhiro Toko; Hiroyuki Takano; Hiroshi Akazawa; Ryozo Nagai; Issei Komuro
Continuous blockade of L-type Ca2+ channels suppresses activation of calcineurin and development of cardiac hypertrophy in spontaneously hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(1):117-24.
2002: Tomohiro Harada; Teruhiko Aoyagi; Yoko Endo; Kansei Uno; Katsu Takenaka; Fumitaka Nakamura; Makoto Sonoda; Toshiyuki Takahashi; Tadashi Yamazaki; Yukio Hiroi; Minoru Ohno; Yasunobu Hirata; Ryozo Nagai
Effusive constrictive pericarditis due to rheumatoid arthritis revealed by pericardiocentesis with simultaneous pressure recording--a case report.
Angiology 2002;53(1):105-8.
2002: Katsunori Yonekura; Ikuo Yokoyama; Tohru Ohtake; Yusuke Inoue; Teruhiko Aoyagi; Seiryo Sugiura; Toshimitsu Momose; Kuni Otomo; Ryozo Nagai
Reduced myocardial flow reserve in anatomically normal coronary arteries due to elevated baseline myocardial blood flow in men with old myocardial infarction.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2002;9(1):62-7.
2002: Masataka Sata; Yasunobu Hirata; Ryozo Nagai
[Circulating recipient cells contribute to graft coronary arteriosclerosis].
Journal of cardiology 2002;39(1):48-9.
2002: Tadanori Aizawa; Nobukazu Ishizaka; Shin-Ichi Usui; Noriko Ohashi; Minoru Ohno; Ryozo Nagai
Angiotensin II and catecholamines increase plasma levels of 8-epi-prostaglandin F(2alpha) with different pressor dependencies in rats.
Hypertension 2002;39(1):149-54.
2002: Nobukazu Ishizaka; Tadanori Aizawa; Minoru Ohno; Shin-ichi Usui Si; Ichiro Mori; Shiow-Shih Tang; Julie R Ingelfinger; Satoshi Kimura; Ryozo Nagai
Regulation and localization of HSP70 and HSP25 in the kidney of rats undergoing long-term administration of angiotensin II.
Hypertension 2002;39(1):122-8.
2002: Nobukazu Ishizaka; Tadanori Aizawa; Ieharu Yamazaki; Shin-ichi Usui; Ichiro Mori; Kiyoshi Kurokawa; Shiow-Shih Tang; Julie R Ingelfinger; Minoru Ohno; Ryozo Nagai
Abnormal iron deposition in renal cells in the rat with chronic angiotensin II administration.
Laboratory investigation; a journal of technical methods and pathology 2002;82(1):87-96.
2002: Hiroyuki Morita; Yuichiro Saito; Masahiko Kurabayashi; Ryozo Nagai
Diet-induced mild hyperhomocysteinemia and increased salt intake diminish vascular endothelial function in a synergistic manner.
Journal of hypertension 2002;20(1):55-62.
2002: Mahito Sato; Toru Tanaka; Toshitaka Maeno; Yoshichika Sando; Tatsuo Suga; Yuri Maeno; Hiroko Sato; Ryozo Nagai; Masahiko Kurabayashi
Inducible expression of endothelial PAS domain protein-1 by hypoxia in human lung adenocarcinoma A549 cells. Role of Src family kinases-dependent pathway.
American journal of respiratory cell and molecular biology 2002;26(1):127-34.
2001: Akio Saiura; Masataka Sata; Yasunobu Hirata; Ryozo Nagai; Makuuchi Masatoshi
Tranilast inhibits transplant-associated coronary arteriosclerosis in a murine model of cardiac transplantation.
European journal of pharmacology 2001;433(2-3):163-8.
2001: Ryuichi Aikawa; Toshio Nagai; Masatsugu Tanaka; Yunzeng Zou; T Ishihara; Hiroyuki Takano; H Hasegawa; Hiroshi Akazawa; Miho Mizukami; Ryozo Nagai; Issei Komuro
Reactive oxygen species in mechanical stress-induced cardiac hypertrophy.
Biochemical and biophysical research communications 2001;289(4):901-7.
2001: Yuichi Kaji; Shiro Amano; Tomohiko Usui; Kaori Suzuki; Sumiyoshi Tanaka; Tetsuro Oshika; Ryozo Nagai; Seikoh Horiuchi
Advanced glycation end products in Descemet's membrane and their effect on corneal endothelial cell.
Current eye research 2001;23(6):469-77.
2001: Ryozo Nagai; Takahiro Suzuki; Kenichi Aizawa; Saku Miyamoto; Toshihiro Amaki; Keiko Kawai-Kowase; Kenichi Sekiguchi; Masahiko Kurabayashi
Phenotypic modulation of vascular smooth muscle cells: dissection of transcriptional regulatory mechanisms.
Annals of the New York Academy of Sciences 2001;947():56-66; discussion 66-7.
2001: Yasuharu Imai; T Shiindo; Koji Maemura; Yukiko Kurihara; Ryozo Nagai; Hiroki Kurihara
Evidence for the physiological and pathological roles of adrenomedullin from genetic engineering in mice.
Annals of the New York Academy of Sciences 2001;947():26-33; discussion 33-4.
2001: Yoshinori Seko; N Takahashi; H Oshima; O Shimozato; Hisaya Akiba; K Takeda; Tetsuji Kobata; Hideo Yagita; Ko Okumura; Masahiko Azuma; Ryozo Nagai
Expression of tumour necrosis factor (TNF) ligand superfamily co-stimulatory molecules CD30L, CD27L, OX40L, and 4-1BBL in murine hearts with acute myocarditis caused by Coxsackievirus B3.
The Journal of pathology 2001;195(5):593-603.
2001: Yoshio Oh-hashi; Takayuki Shindo; Yukiko Kurihara; Takasuke Imai; Yuhui Wang; Hiroyuki Morita; Yasushi Imai; Yuji Kayaba; Hiroaki Nishimatsu; Y Suematsu; Yasunobu Hirata; Yoshio Yazaki; Ryozo Nagai; Tomoyuki Kuwaki; Hiroki Kurihara
Elevated sympathetic nervous activity in mice deficient in alphaCGRP.
Circulation research 2001;89(11):983-90.
2001: Y Zou; Ryozo Nagai; T Yamazaki
Urotensin II induces hypertrophic responses in cultured cardiomyocytes from neonatal rats.
FEBS letters 2001;508(1):57-60.
2001: Toshimasa Yamauchi; Junji Kamon; Hironori Waki; Koji Murakami; Kiyoto Motojima; Kajuro Komeda; Tomohiro Ide; Naoto Kubota; Yasuo Terauchi; Kazuyuki Tobe; Hiroshi Miki; Atsushi Tsuchida; Yasuo Akanuma; Ryozo Nagai; Satoshi Kimura; Takashi Kadowaki
The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance.
The Journal of biological chemistry 2001;276(44):41245-54.
2001: T Yamagishi; Yuichiro Saito; Tetsuya Nakamura; S Takeda; H Kanai; Hiroyuki Sumino; Makoto Kuro-o; Yo-ichi Nabeshima; Masahiko Kurabayashi; Ryozo Nagai
Troglitazone improves endothelial function and augments renal klotho mRNA expression in Otsuka Long-Evans Tokushima Fatty (OLETF) rats with multiple atherogenic risk factors.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(6):705-9.
2001: Hiroaki Nishimatsu; Yasunobu Hirata; Hiroshi Hayakawa; Daisuke Nagata; Hiroshi Satonaka; Etsu Suzuki; S Horie; T Takeuchi; Nobutaka Ohta; Yukio Homma; Shigeru Minowada; Ryozo Nagai; K Kawabe; Tadaichi Kitamura
Effects of intracavernous administration of adrenomedullin on erectile function in rats.
Peptides 2001;22(11):1913-8.
2001: Masataka Sata; Seiryo Sugiura; Masao Yoshizumi; Yasuyoshi Ouchi; Yasunobu Hirata; Ryozo Nagai
Acute and chronic smooth muscle cell apoptosis after mechanical vascular injury can occur independently of the Fas-death pathway.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(11):1733-7.
2001: Masataka Sata; Hiroaki Nishimatsu; Etsu Suzuki; S Sugiura; M Yoshizumi; Y Ouchi; Yasunobu Hirata; Ryozo Nagai
Endothelial nitric oxide synthase is essential for the HMG-CoA reductase inhibitor cerivastatin to promote collateral growth in response to ischemia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2530-2.
2001: Kazuyuki Tobe; Ryo Suzuki; Masashi Aoyama; Toshimasa Yamauchi; Junji Kamon; Naoto Kubota; Yasuo Terauchi; Junji Matsui; Yasuo Akanuma; Satoshi Kimura; J Tanaka; Masato Abe; J Ohsumi; Ryozo Nagai; Takashi Kadowaki
Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver.
The Journal of biological chemistry 2001;276(42):38337-40.
2001: Takayuki Shindo; Yukiko Kurihara; Hiroaki Nishimatsu; Nobuo Moriyama; Masao Kakoki; Y Wang; Yasuharu Imai; Aya Ebihara; Tomoyuki Kuwaki; Kihwan Ju; Naoto Minamino; Kenji Kangawa; T Ishikawa; M Fukuda; Y Akimoto; H Kawakami; T Imai; Hiroyuki Morita; Yoshio Yazaki; Ryozo Nagai; Yasunobu Hirata; Hiroki Kurihara
Vascular abnormalities and elevated blood pressure in mice lacking adrenomedullin gene.
Circulation 2001;104(16):1964-71.
2001: Alyssa H Hasty; Hitoshi Shimano; Jun-ichi Osuga; I Namatame; Akimitsu Takahashi; Naoya Yahagi; S Perrey; Yoko Iizuka; Yoshiaki Tamura; Michiyo Amemiya-Kudo; Tomohiro Yoshikawa; Hiroaki Okazaki; Ken Ohashi; Kenji Harada; Takashi Matsuzaka; Hirohito Sone; Takanari Gotoda; Ryozo Nagai; Shun Ishibashi; Nobuhiro Yamada
Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor.
The Journal of biological chemistry 2001;276(40):37402-8.
2001: Tokiharu Takahashi; Yasuyuki Sugishita; Koichiro Kinugawa; Takao Shimizu; Atsushi Yao; Kenji Harada; Hiroshi Matsui; Ryozo Nagai
Ets-1 is involved in transcriptional regulation of the chick inducible nitric oxide synthase gene in embryonic ventricular myocytes.
Molecular and cellular biochemistry 2001;226(1-2):57-65.
2001: Kenji Harada; Takao Shimizu; Yasuyuki Sugishita; Atsushi Yao; Jun-Ichi Suzuki; Katsu Takenaka; Yasunobu Hirata; Ryozo Nagai; Tokiharu Takahashi
Hypertrophic cardiomyopathy with midventricular obstruction and apical aneurysm: a case report.
Japanese circulation journal 2001;65(10):915-9.
2001: Toshimasa Yamauchi; Hironori Waki; Junji Kamon; Koji Murakami; Kiyoto Motojima; Kajuro Komeda; Hiroshi Miki; Naoto Kubota; Yasuo Terauchi; Atsushi Tsuchida; Nobuyo Tsuboyama-Kasaoka; N Yamauchi; Tomohiro Ide; W Hori; Shigeaki Kato; Masashi Fukayama; Yasuo Akanuma; Osamu Ezaki; Akiko Itai; Ryozo Nagai; Satoshi Kimura; Kazuyuki Tobe; Hiroyuki Kagechika; Koichi Shudo; Takashi Kadowaki
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
The Journal of clinical investigation 2001;108(7):1001-13.
2001: Toru Hosoda; Koshiro Monzen; Yukio Hiroi; Toru Oka; Eiki Takimoto; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
A novel myocyte-specific gene Midori promotes the differentiation of P19CL6 cells into cardiomyocytes.
The Journal of biological chemistry 2001;276(38):35978-89.
2001: Tomohiro Harada; Fumitaka Nakamura; Yasuo Ikeda; S Usui; Naoyuki Tsuchiya; Minoru Ohno; Yasunobu Hirata; Ryozo Nagai
Successful catheter intervention for acute coronary syndrome in a patient with antiphospholipid syndrome.
Japanese heart journal 2001;42(5):627-31.
2001: So-ichiro Yasuda; Seiryo Sugiura; Naoshi Kobayakawa; Hiroshi Fujita; Hiroshi Yamashita; Kaoru Katoh; Yasutake Saeki; H Kaneko; Y Suda; Ryozo Nagai; Haruo Sugi
A novel method to study contraction characteristics of a single cardiac myocyte using carbon fibers.
American journal of physiology. Heart and circulatory physiology 2001;281(3):H1442-6.
2001: N Manabe; Hiroshi Kawaguchi; Hirotaka Chikuda; Chisato Miyaura; Masaki Inada; Ryozo Nagai; Yo-ichi Nabeshima; Kozo Nakamura; Angus M Sinclair; Richard Scheuermann; Makoto Kuro-o
Connection between B lymphocyte and osteoclast differentiation pathways.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(5):2625-31.
2001: Yasunobu Hirata; A Matsumoto; T Aoyagi; K Yamaoki; Issei Komuro; Takahiro Suzuki; T Ashida; T Sugiyama; Yusuke Hada; Iwao Kuwajima; M Nishinaga; H Akioka; O Nakajima; Ryozo Nagai; Yoshio Yazaki
Measurement of plasma brain natriuretic peptide level as a guide for cardiac overload.
Cardiovascular research 2001;51(3):585-91.
2001: Misako Hangaishi; Harushi Nakajima; Junichi Taguchi; R Igarashi; J Hoshino; Kiyoshi Kurokawa; Satoshi Kimura; Ryozo Nagai; Minoru Ohno
Lecithinized Cu, Zn-superoxide dismutase limits the infarct size following ischemia-reperfusion injury in rat hearts in vivo.
Biochemical and biophysical research communications 2001;285(5):1220-5.
2001: Toshimasa Yamauchi; Junji Kamon; Hironori Waki; Yasuo Terauchi; Naoto Kubota; Kazuo Hara; Yasumichi Mori; Tomohiro Ide; Koji Murakami; Nobuyo Tsuboyama-Kasaoka; Osamu Ezaki; Yasuo Akanuma; Oksana Gavrilova; C Vinson; Marc L Reitman; Hiroyuki Kagechika; Koichi Shudo; M Yoda; Y Nakano; Kazuyuki Tobe; Ryozo Nagai; Satoshi Kimura; Motowo Tomita; philippe froguel; Takashi Kadowaki
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.
Nature medicine 2001;7(8):941-6.
2001: Harushi Nakajima; Misako Hangaishi; Nobukazu Ishizaka; Junichi Taguchi; R Igarashi; Y Mizushima; Ryozo Nagai; Minoru Ohno
Lecithinized copper, zinc-superoxide dismutase ameliorates ischemia-induced myocardial damage.
Life sciences 2001;69(8):935-44.
2001: Yunzeng Zou; A Yao; Weidong Zhu; Sumiyo Kudoh; Yukio Hiroi; Masaki Shimoyama; Hiroki Uozumi; Osami Kohmoto; Tokiharu Takahashi; Futoshi Shibasaki; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Isoproterenol activates extracellular signal-regulated protein kinases in cardiomyocytes through calcineurin.
Circulation 2001;104(1):102-8.
2001: Yunzeng Zou; Yukio Hiroi; Hiroki Uozumi; Eiki Takimoto; Haruhiro Toko; Weidong Zhu; Sumiyo Kudoh; Miho Mizukami; Masaki Shimoyama; Futoshi Shibasaki; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Calcineurin plays a critical role in the development of pressure overload-induced cardiac hypertrophy.
Circulation 2001;104(1):97-101.
2001: T Kawamura; Yoshichika Sando; Syunji Tajima; Tatsuya Hosono; Mahito Sato; Yuri Maeno; Toshitaka Maeno; Tatsuo Suga; Masahiko Kurabayashi; Ryozo Nagai
Pulmonary intravascular lymphoma complicated with Pneumocystis carinii pneumonia: a case report.
Japanese journal of clinical oncology 2001;31(7):333-6.
2001: Yukio Hiroi; Junya Hiroi; Sumiyo Kudoh; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Two distinct mechanisms of angiotensin II-induced negative regulation of the mitogen-activated protein kinases in cultured cardiac myocytes.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(4):385-94.
2001: Ikuo Yokoyama; Katsunori Yonekura; Yusuke Inoue; Kuni Ohtomo; Ryozo Nagai
Long-term effect of simvastatin on the improvement of impaired myocardial flow reserve in patients with familial hypercholesterolemia without gender variance.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2001;8(4):445-51.
2001: Kenji Harada; Yasuyuki Sugishita; Takao Shimizu; Atsushi Yao; Hiroshi Matsui; Osami Kohmoto; Takashi Serizawa; Ryozo Nagai; Tokiharu Takahashi
Left ventricular relaxation abnormality is detectable by analysis of the relaxation time constant in patients with atrial fibrillation.
Japanese circulation journal 2001;65(7):610-6.
2001: Ikuo Yokoyama; Katsunori Yonekura; Toshiyuki Moritan; M Tateno; Toshimitsu Momose; Kuni Ohtomo; Yusuke Inoue; Ryozo Nagai
Troglitazone improves whole-body insulin resistance and skeletal muscle glucose use in type II diabetic patients.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(7):1005-10.
2001: Yukio Hiroi; S Kudoh; Koshiro Monzen; Y Ikeda; Yoshio Yazaki; Ryozo Nagai; I Komuro
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation.
Nature genetics 2001;28(3):276-80.
2001: Atai Watanabe; Masahiko Kurabayashi; Masashi Arai; Kenichi Sekiguchi; Ryozo Nagai
Combined effect of retinoic acid and basic FGF on PAI-1 gene expression in vascular smooth muscle cells.
Cardiovascular research 2001;51(1):151-9.
2001: Hiroki Uozumi; Yukio Hiroi; Yunzeng Zou; Eiki Takimoto; Haruhiro Toko; Pei Niu; Masaki Shimoyama; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
gp130 plays a critical role in pressure overload-induced cardiac hypertrophy.
The Journal of biological chemistry 2001;276(25):23115-9.
2001: Yasushi Fukushima; Tatsuya Saitoh; Motonobu Anai; Toshio Ogihara; Kouichi Inukai; Masako Funaki; Hideyuki Sakoda; Yukiko Onishi; Hiraku Ono; Midori Fujishiro; Takashi Ishikawa; K Takata; Ryozo Nagai; Masao Omata; Tomoichiro Asano
Palmitoylation of the canine histamine H2 receptor occurs at Cys(305) and is important for cell surface targeting.
Biochimica et biophysica acta 2001;1539(3):181-91.
2001: N Arai; A Matsumoto; N Nishikawa; K Yonekura; Y Eto; Yukihiro Kuwada; S Sugiura; Katsu Takenaka; Yasunobu Hirata; Ryozo Nagai; T Aoyagi
Beta-blocker therapy improved symptoms and exercise capacity in a patient with dynamic intra-right ventricular obstruction: an atypical Form of double-chambered right ventricle.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2001;14(6):650-3.
2001: Koshiro Monzen; Yukio Hiroi; Sumiyo Kudoh; Hiroshi Akazawa; Toru Oka; Eiki Takimoto; Doubun Hayashi; Toru Hosoda; M Kawabata; Kohei Miyazono; S Ishii; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation.
The Journal of cell biology 2001;153(4):687-98.
2001: K Chisaki; Toshiaki Nakajima; Kuniaki Iwasawa; Haruko Iida; A Matsumoto; M Tada; Y Komatsu; K Hirose; K Miyamoto; Yukichi Okuda; Y Shiratori; Atsuo Goto; Yasunobu Hirata; Ryozo Nagai; Masao Omata
Enhancement of endothelial nitric oxide production by chenodeoxycholic acids in patients with hepatobiliary diseases.
Japanese heart journal 2001;42(3):339-53.
2001: Susumu Sakurai; Katsu Takenaka; Ichiro Shiojima; F Watanabe; Makoto Sonoda; Kansei Uno; Yukihiro Kuwada; Kazuhiko Nakahara; Ryozo Nagai
Traumatic tricuspid insufficiency.
Echocardiography (Mount Kisco, N.Y.) 2001;18(4):303-4.
2001: Ryuichi Tozawa; Shun Ishibashi; Jun-ichi Osuga; Kazuhiko Yamamoto; Hiroaki Yagyu; Ken Ohashi; Yoshiaki Tamura; Naoya Yahagi; Yoko Iizuka; Hiroaki Okazaki; Kenji Harada; Takanari Gotoda; Hitoshi Shimano; Satoshi Kimura; Ryozo Nagai; Nobuhiro Yamada
Asialoglycoprotein receptor deficiency in mice lacking the major receptor subunit. Its obligate requirement for the stable expression of oligomeric receptor.
The Journal of biological chemistry 2001;276(16):12624-8.
2001: H Miki; T Yamauchi; R Suzuki; Kajuro Komeda; Atsushi Tsuchida; Naoto Kubota; Yasuo Terauchi; Junji Kamon; Yasushi Kaburagi; Junji Matsui; Yasuo Akanuma; Ryozo Nagai; Satoshi Kimura; Kazuyuki Tobe; T Kadowaki
Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation.
Molecular and cellular biology 2001;21(7):2521-32.
2001: Tokiharu Takahashi; Yasuyuki Sugishita; Takefumi Nojiri; Takao Shimizu; Atsushi Yao; Koichiro Kinugawa; Kenji Harada; Ryozo Nagai
Cloning of hypoxia-inducible factor 1alpha cDNA from chick embryonic ventricular myocytes.
Biochemical and biophysical research communications 2001;281(4):1057-62.
2001: K Aizawa; Yoriaki Kaneko; Toshiharu Yamagishi; T Utsugi; T Suzuki; Susumu Ishikawa; A Otaki; Yasuo Morishita; Akira Hasegawa; Masahiko Kurabayashi; Ryozo Nagai
Oozing from the pericardium as an etiology of cardiac tamponade associated with screw-in atrial leads.
Pacing and clinical electrophysiology : PACE 2001;24(3):381-3.
2001: Y Oishi; Yoshichika Sando; Syunji Tajima; Toshitaka Maeno; Yuri Maeno; Mahito Sato; Tatsuya Hosono; Tatsuo Suga; Masahiko Kurabayashi; Ryozo Nagai
Indomethacin induced bulky lymphadenopathy and eosinophilic pneumonia.
Respirology (Carlton, Vic.) 2001;6(1):57-60.
2001: Z Chen; Shun Ishibashi; S Perrey; Takanari Gotoda; Tetsuya Kitamine; Yoshiaki Tamura; Hiroaki Okazaki; Naoya Yahagi; Yoko Iizuka; Futoshi Shionoiri; Ken Ohashi; Kenji Harada; Hitoshi Shimano; Ryozo Nagai; Nobuhiro Yamada
Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(3):372-7.
2001: Mamoru Manita; Yoriaki Kaneko; Yasuhiro Taniguchi; Tadashi Nakajima; Toshio Ito; Masahiko Kurabayashi; Ryozo Nagai
Typical atrial flutterlike tachycardia developing after inferior vena cava-tricuspid annulus isthmus ablation.
Pacing and clinical electrophysiology : PACE 2001;24(2):231-4.
2001: Masaki Shimoyama; Doubun Hayashi; Yunzeng Zou; Eiki Takimoto; Miho Mizukami; Koshiro Monzen; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
[Calcineurin inhibitor attenuates the development and induces the regression of cardiac hypertrophy in rats with salt-sensitive hypertension].
Journal of cardiology 2001;37(2):114-8.
2001: Hiroyuki Morita; Hiroki Kurihara; Y Imai; T Sugiyama; C Hamada; E Sakai; M Mori; Ryozo Nagai
Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and myocardial infarction in Japanese. An approach entailing melting curve analysis with specific fluorescent hybridization probes.
Thrombosis and haemostasis 2001;85(2):226-30.
2001: Tadanori Aizawa; Nobukazu Ishizaka; Kiyoshi Kurokawa; Ryozo Nagai; H Nakajima; Junichi Taguchi; Minoru Ohno
Different effects of angiotensin II and catecholamine on renal cell apoptosis and proliferation in rats.
Kidney international 2001;59(2):645-53.
2001: Kenichi Sekiguchi; Masahiko Kurabayashi; Yuko Oyama; Y Aihara; Toru Tanaka; H Sakamoto; Y i Hoshino; T Kanda; T Yokoyama; Y Shimomura; H Iijima; Yoshio Ohyama; Ryozo Nagai
Homeobox protein Hex induces SMemb/nonmuscle myosin heavy chain-B gene expression through the cAMP-responsive element.
Circulation research 2001;88(1):52-8.
2001: Hiroyoshi Kanai; Toru Tanaka; Y Aihara; S Takeda; M Kawabata; K Miyazono; Ryozo Nagai; Masahiko Kurabayashi
Transforming growth factor-beta/Smads signaling induces transcription of the cell type-restricted ankyrin repeat protein CARP gene through CAGA motif in vascular smooth muscle cells.
Circulation research 2001;88(1):30-6.
2001: Hiroyuki Morita; Hiroki Kurihara; S Yoshida; Yuichiro Saito; Takayuki Shindo; Yoshio Oh-hashi; Yukiko Kurihara; Yoshio Yazaki; Ryozo Nagai
Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury.
Circulation 2001;103(1):133-9.
2001: Yasushi Fukushima; Tatsuya Saitoh; Motonobu Anai; K Tsukuda; Yukiko Onishi; Hideyuki Sakoda; Kouichi Inukai; Toshio Ogihara; Masako Funaki; Hiraku Ono; Midori Fujishiro; Takashi Ishikawa; Ryozo Nagai; Masao Omata; Tomoichiro Asano
G649, an allelic variant of the human H2 receptor with low basal activity, is resistant to upregulation upon antagonist exposure.
The pharmacogenomics journal 2001;1(1):78-83.
2001: Hiroyasu Iwasa; Masahiko Kurabayashi; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Genetic variations in five genes involved in the excitement of cardiomyocytes.
Journal of human genetics 2001;46(9):549-52.
2001: Katsu Takenaka; Yukihiro Kuwada; Makoto Sonoda; Kansei Uno; M Asakawa; Susumu Sakurai; T Takahashi; Kazuyoshi Sasaki; Masunori Matsuzaki; A Kikuchi; R Amagai; N Furudate; Ryozo Nagai
Anthracycline-induced cardiomyopathies evaluated by tissue Doppler tracking system and strain rate imaging.
Journal of cardiology 2001;37 Suppl 1():129-32.
2001: Hiroyasu Iwasa; Masahiko Kurabayashi; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Multiple single-nucleotide polymorphisms (SNPs) in the Japanese population in six candidate genes for long QT syndrome.
Journal of human genetics 2001;46(3):158-62.
2001: T Itoh; K Kikuchi; Y Odagawa; S Takata; K Yano; S Okada; N Haneda; Seishi Ogawa; O Nakano; Y Kawahara; H Kasai; T Nakayama; T Fukutomi; Harumizu Sakurada; A Shimizu; Yoshio Yazaki; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Correlation of genetic etiology with response to beta-adrenergic blockade among symptomatic patients with familial long-QT syndrome.
Journal of human genetics 2001;46(1):38-40.
2001: Tsutomu Iwasaki; T Iwasaki; Y Aihara; Tsugiyasu Kanda; Noboru Oriuchi; Keigo Endo; H Katoh; Takahiro Suzuki; Ryozo Nagai
Immunoscintigraphy of aortic dissection with 99mTc-labeled murine anti-smooth muscle myosin monoclonal antibody in rats.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(1):130-7.
2000: Misako Hangaishi; Nobukazu Ishizaka; Tadanori Aizawa; Yukiko Kurihara; Junichi Taguchi; Ryozo Nagai; Satoshi Kimura; Minoru Ohno
Induction of heme oxygenase-1 can act protectively against cardiac ischemia/reperfusion in vivo.
Biochemical and biophysical research communications 2000;279(2):582-8.
2000: T Ogata; Masahiko Kurabayashi; Y i Hoshino; Kenichi Sekiguchi; Keiko Kawai-Kowase; Susumu Ishikawa; Yasuo Morishita; Ryozo Nagai
Inducible expression of basic transcription factor-binding protein 2 (BTEB2), a member of zinc finger family of transcription factors, in cardiac allograft vascular disease.
Transplantation 2000;70(11):1653-6.
2000: Ryuichi Aikawa; Masao Nawano; Y Gu; Hideki Katagiri; Tomoichiro Asano; Weidong Zhu; Ryozo Nagai; Issei Komuro
Insulin prevents cardiomyocytes from oxidative stress-induced apoptosis through activation of PI3 kinase/Akt.
Circulation 2000;102(23):2873-9.
2000: Toshio Ito; Yoriaki Kaneko; Yasuhiro Taniguchi; Tadashi Nakajima; Mamoru Manita; Masahiko Suguta; Masahiko Kurabayashi; Ryozo Nagai
Long RP tachycardia with RR alternation.
Pacing and clinical electrophysiology : PACE 2000;23(12):2128-30.
2000: Yuri Maeno; Yoshichika Sando; M Ubukata; Toshitaka Maeno; Syunji Tajima; Tatsuya Hosono; Mahito Sato; M Tsukagoshi; Tatsuo Suga; Masahiko Kurabayashi; Ryozo Nagai
Pulmonary nocardiosis during immunosuppressive therapy for idiopathic pulmonary fibrosis.
Respirology (Carlton, Vic.) 2000;5(4):393-5.
2000: Hiroyuki Sumino; Tetsuya Nakamura; Tsugiyasu Kanda; K Sato; Tetsuo Sakamaki; Toru Takahashi; Yuichiro Saito; J Hoshino; Toshiaki Kurashina; Ryozo Nagai
Effect of enalapril on exhaled nitric oxide in normotensive and hypertensive subjects.
Hypertension 2000;36(6):934-40.
2000: Tsugiyasu Kanda; Toru Tanaka; Kenichi Sekiguchi; Y Seta; Masashi Kurimoto; J E Wilson McManus; Ryozo Nagai; Dawei Yang; Bruce M McManus; Isao Kobayashi
Effect of interleukin-18 on viral myocarditis: enhancement of interferon- gamma and natural killer cell activity.
Journal of molecular and cellular cardiology 2000;32(12):2163-71.
2000: Y i Hoshino; Masahiko Kurabayashi; Tsugiyasu Kanda; Akira Hasegawa; Hironosuke Sakamoto; Ei-ichi Okamoto; K Kowase; N Watanabe; Ichiro Manabe; Takahiro Suzuki; Akihiko Nakano; S Takase; Josiah N Wilcox; Ryozo Nagai
Regulated expression of the BTEB2 transcription factor in vascular smooth muscle cells: analysis of developmental and pathological expression profiles shows implications as a predictive factor for restenosis.
Circulation 2000;102(20):2528-34.
2000: Weidong Zhu; Ichiro Shiojima; Yukio Hiroi; Yunzeng Zou; Hiroshi Akazawa; Miho Mizukami; Haruhiro Toko; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease.
The Journal of biological chemistry 2000;275(45):35291-6.
2000: S Saito; Yukio Hiroi; Yunzeng Zou; Ryuichi Aikawa; Haruhiro Toko; Futoshi Shibasaki; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
beta-Adrenergic pathway induces apoptosis through calcineurin activation in cardiac myocytes.
The Journal of biological chemistry 2000;275(44):34528-33.
2000: Ei-Ichi Fukui; Takeshi Yamashita; K Sezaki; Kohsuke Ajiki; Masayasu Inoue; Noriyuki Hayami; Yuji Kasaoka; Masao Omata; Yuji Murakawa; Ryozo Nagai
Overdrive suppression of antegrade conduction over the accessory pathway.
Japanese heart journal 2000;41(6):767-72.
2000: Yuji Murakawa; Takeshi Yamashita; Kohsuke Ajiki; Jun-Ichi Suzuki; Noriyuki Hayami; Ei-Ichi Fukui; Yuji Kasaoka; Masao Omata; Ryozo Nagai
Is the QT interval an indicator of autonomic state?
Japanese heart journal 2000;41(6):713-21.
2000: T Ogata; Masahiko Kurabayashi; Y i Hoshino; Susumu Ishikawa; Izumi Takeyoshi; Yasuo Morishita; Ryozo Nagai
Inducible expression of BTEB2, a member of the zinc-finger family of transcription factors, in cardiac allograft arteriosclerosis.
Transplantation proceedings 2000;32(7):2032-3.
2000: Naoto Kubota; Kazuyuki Tobe; Yasuo Terauchi; Kazuhiro Eto; Toshimasa Yamauchi; Ryo Suzuki; Yoshiharu Tsubamoto; Kajuro Komeda; R Nakano; H Miki; Shinobu Satoh; Hisahiko Sekihara; S Sciacchitano; MA Lesniak; Shin Aizawa; Ryozo Nagai; Satoshi Kimura; Yasuo Akanuma; Simeon I Taylor; Takashi Kadowaki
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.
Diabetes 2000;49(11):1880-9.
2000: Masataka Sata; Yasuhiro Maejima; F Adachi; Keiko Fukino; Akio Saiura; Seiryo Sugiura; Teruhiko Aoyagi; Yasushi Imai; H Kurihara; K Kimura; M Omata; M Makuuchi; Yasunobu Hirata; Ryozo Nagai
A mouse model of vascular injury that induces rapid onset of medial cell apoptosis followed by reproducible neointimal hyperplasia.
Journal of molecular and cellular cardiology 2000;32(11):2097-104.
2000: Toru Tanaka; Hiroyoshi Kanai; Kenichi Sekiguchi; Yasushi Aihara; Tomoyuki Yokoyama; Masashi Arai; Tsugiyasu Kanda; Ryozo Nagai; Masahiko Kurabayashi
Induction of VEGF gene transcription by IL-1 beta is mediated through stress-activated MAP kinases and Sp1 sites in cardiac myocytes.
Journal of molecular and cellular cardiology 2000;32(11):1955-67.
2000: Toshimasa Yamauchi; N Yamauchi; Keisuke Ueki; Takashi Sugiyama; Hironori Waki; Hiroshi Miki; Kazuyuki Tobe; S Matsuda; T Tsushima; Tadashi Yamamoto; Tomoyuki Fujita; Y Taketani; Masashi Fukayama; Satoshi Kimura; Yoshio Yazaki; Ryozo Nagai; Takashi Kadowaki
Constitutive tyrosine phosphorylation of ErbB-2 via Jak2 by autocrine secretion of prolactin in human breast cancer.
The Journal of biological chemistry 2000;275(43):33937-44.
2000: Masaki Shimoyama; Doubun Hayashi; Yunzeng Zou; Eiki Takimoto; Miho Mizukami; Koshiro Monzen; Sumiyo Kudoh; Yukio Hiroi; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Calcineurin inhibitor attenuates the development and induces the regression of cardiac hypertrophy in rats with salt-sensitive hypertension.
Circulation 2000;102(16):1996-2004.
2000: Alyssa H Hasty; Hitoshi Shimano; Naoya Yahagi; Michiyo Amemiya-Kudo; S Perrey; Tomohiro Yoshikawa; Jun-ichi Osuga; Hiroaki Okazaki; Yoshiaki Tamura; Yoko Iizuka; Futoshi Shionoiri; Ken Ohashi; Kenji Harada; Takanari Gotoda; Ryozo Nagai; Shun Ishibashi; Nobuhiro Yamada
Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level.
The Journal of biological chemistry 2000;275(40):31069-77.
2000: Shunichi Toshima; Akira Hasegawa; Masahiko Kurabayashi; H Itabe; T Takano; J Sugano; K Shimamura; J Kimura; I Michishita; Toru Suzuki; Ryozo Nagai
Circulating oxidized low density lipoprotein levels. A biochemical risk marker for coronary heart disease.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(10):2243-7.
2000: Yuichiro Saito; Tetsuya Nakamura; Yoshio Ohyama; Takahiro Suzuki; A Iida; T Shiraki-Iida; Makoto Kuro-o; Yo-ichi Nabeshima; Masahiko Kurabayashi; Ryozo Nagai
In vivo klotho gene delivery protects against endothelial dysfunction in multiple risk factor syndrome.
Biochemical and biophysical research communications 2000;276(2):767-72.
2000: Takashi Nakajima; Masahiko Kurabayashi; Yoshio Ohyama; Yoshiaki Kaneko; T Furukawa; T Itoh; Y Taniguchi; Toru Tanaka; Y Nakamura; M Hiraoka; Ryozo Nagai
Characterization of S818L mutation in HERG C-terminus in LQT2. Modification of activation-deactivation gating properties.
FEBS letters 2000;481(2):197-203.
2000: H Ikeuchi; Yoshichika Sando; Syunji Tajima; Mahito Sato; Tatsuya Hosono; Toshitaka Maeno; Yuri Maeno; Tatsuo Suga; Masahiko Kurabayashi; Ryozo Nagai
[PL granule-induced pneumonia requiring mechanical ventilation].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2000;38(9):682-6.
2000: Ryuichi Aikawa; Issei Komuro; Ryozo Nagai; Yoshio Yazaki
Rho plays an important role in angiotensin II-induced hypertrophic responses in cardiac myocytes.
Molecular and cellular biochemistry 2000;212(1-2):177-82.
2000: Toshihiro Utsugi; T Ohno; Yoshio Ohyama; Tsuyoshi Uchiyama; Y Saito; Y Matsumura; H Aizawa; H Itoh; Masahiko Kurabayashi; Shoji Kawazu; Shoichi Tomono; Y Oka; T Suga; Makoto Kuro-o; Y Nabeshima; Ryozo Nagai
Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging.
Metabolism: clinical and experimental 2000;49(9):1118-23.
2000: Yoshinori Seko; N Takahashi; Yusuke Tada; Hideo Yagita; Ko Okumura; Ryozo Nagai
Restricted usage of T-cell receptor Vgamma-Vdelta genes and expression of costimulatory molecules in Takayasu's arteritis.
International journal of cardiology 2000;75 Suppl 1():S77-83; discussion S85-7.
2000: Masatoshi Suzuki; Nobukazu Ishizaka; W M Hwang; Kazuhisa Tsukamoto; K Minami; Tadanori Aizawa; Ichiro Mori; Junichi Taguchi; Ryozo Nagai; Minoru Ohno
Application of hydrostatic pressure facilitates ex vivo adenovirus gene transfer into rabbit aortas.
Biochemical and biophysical research communications 2000;274(2):422-6.
2000: Y Oishi; Masashi Arai; J Kiraku; H Doi; T Uchiyama; Akira Hasegawa; Masahiko Kurabayashi; Ryozo Nagai
Unclassified connective tissue disease presenting as cardiac tamponade: a case report.
Japanese circulation journal 2000;64(8):619-22.
2000: Ken Ohashi; Shun Ishibashi; Jun-ichi Osuga; Ryuichi Tozawa; Kenji Harada; Naoya Yahagi; Futoshi Shionoiri; Yoko Iizuka; Yoshiaki Tamura; Ryozo Nagai; D R Illingworth; Takanari Gotoda; Nobuhiro Yamada
Novel mutations in the microsomal triglyceride transfer protein gene causing abetalipoproteinemia.
Journal of lipid research 2000;41(8):1199-204.
2000: Yukiko Kurihara; Hiroki Kurihara; H Morita; WH Cao; GY Ling; Mamoru Kumada; S Kimura; Ryozo Nagai; Yoshio Yazaki; Tomoyuki Kuwaki
Role of endothelin-1 in stress response in the central nervous system.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(2):R515-21.
2000: I Murata; Makoto Sonoda; T Morita; F Nakamura; Katsu Takenaka; Ryozo Nagai
The clinical significance of reversed flow in the main pulmonary artery detected by doppler color flow imaging.
Chest 2000;118(2):336-41.
2000: Toshiaki Nakajima; Yukichi Okuda; K Chisaki; W S Shin; Kuniaki Iwasawa; Toshihiro Morita; A Matsumoto; J I Suzuki; S Suzuki; Nobuhiro Yamada; Teruhiko Toyo-Oka; Ryozo Nagai; Masao Omata
Bile acids increase intracellular Ca(2+) concentration and nitric oxide production in vascular endothelial cells.
British journal of pharmacology 2000;130(7):1457-67.
2000: Nobukazu Ishizaka; Tadanori Aizawa; Ichiro Mori; Junichi Taguchi; Yoshio Yazaki; Ryozo Nagai; Minoru Ohno
Heme oxygenase-1 is upregulated in the rat heart in response to chronic administration of angiotensin II.
American journal of physiology. Heart and circulatory physiology 2000;279(2):H672-8.
2000: Hitoshi Oonuma; Toshiaki Nakajima; Taiji Nagata; Kuniaki Iwasawa; Yuhui Wang; Hisanori Hazama; Yutaka Morita; Kazuhiko Yamamoto; Ryozo Nagai; Masao Omata
Endothelin-1 is a potent activator of nonselective cation currents in human bronchial smooth muscle cells.
American journal of respiratory cell and molecular biology 2000;23(2):213-21.
2000: Yasushi Aihara; Masahiko Kurabayashi; Toru Tanaka; Shinichi Takeda; Koichi Tomaru; Kenichi Sekiguchi; Yoshio Ohyama; Ryozo Nagai
Doxorubicin represses CARP gene transcription through the generation of oxidative stress in neonatal rat cardiac myocytes: possible role of serine/threonine kinase-dependent pathways.
Journal of molecular and cellular cardiology 2000;32(8):1401-14.
2000: Nobuo Kotajima; T Hirakata; Tsugiyasu Kanda; Tomoyuki Yokoyama; Y Hoshino; Toru Tanaka; Jun'ichi Tamura; Ryozo Nagai; I Kobayasii
Prolongation of QT interval and ventricular septal hypertrophy.
Japanese heart journal 2000;41(4):463-9.
2000: Jun-Ichi Suzuki; Ryozo Nagai; J Nishikawa; K Ohotomo; Teruhiko Toyo-Oka; Masao Omata
Evaluation of the heart with magnetic resonance imaging.
Japanese heart journal 2000;41(4):417-24.
2000: Harushi Nakajima; Nobukazu Ishizaka; Misako Hangaishi; Junichi Taguchi; J Itoh; R Igarashi; Y Mizushima; Ryozo Nagai; Minoru Ohno
Lecithinized copper, zinc-superoxide dismutase ameliorates prolonged hypoxia-induced injury of cardiomyocytes.
Free radical biology & medicine 2000;29(1):34-41.
2000: K Aizawa; Tetsuya Nakamura; Hiroyuki Sumino; Yuichiro Saito; J Hoshino; Toshiaki Kurashina; Hisao Kumakura; S Ichikawa; Ryozo Nagai
Renovascular hypertension observed in a patient with antiphospholipid-antibody syndrome.
Japanese circulation journal 2000;64(7):541-3.
2000: Shu Kasama; Takuji Toyama; Hiroshi Hoshizaki; Shigeru Oshima; Koichi Taniguchi; Tsutomu Iwasaki; Takahiro Suzuki; Ryozo Nagai
[Prediction of cardiac sympathetic nerve activity and cardiac functional outcome after treatment in patients with dilated cardiomyopathy: examination using dobutamine gated blood pool scintigraphy].
Journal of cardiology 2000;36(1):29-35.
2000: Hiroyuki Morita; Hiroki Kurihara; Tomoaki Kuwaki; C Hamada; M Kitaoka; S Suzuki; Yoshio Yazaki; Ryozo Nagai
Homocysteine as a risk factor for restenosis after coronary angioplasty.
Thrombosis and haemostasis 2000;84(1):27-31.
2000: Masataka Sata; Masao Kakoki; Daisuke Nagata; Hiroaki Nishimatsu; Etsu Suzuki; T Aoyagi; S Sugiura; H Kojima; Tetsuo Nagano; Kenji Kangawa; Hisayuki Matsuo; Masao Omata; Ryozo Nagai; Yasunobu Hirata
Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism.
Hypertension 2000;36(1):83-8.
2000: Yasushi Aihara; Masahiko Kurabayashi; Yuichiro Saito; Yoshio Ohyama; Toru Tanaka; Shinichi Takeda; Koichi Tomaru; Kenichi Sekiguchi; Masashi Arai; Tetsuya Nakamura; Ryozo Nagai
Cardiac ankyrin repeat protein is a novel marker of cardiac hypertrophy: role of M-CAT element within the promoter.
Hypertension 2000;36(1):48-53.
2000: Yukio Hiroi; R Chen; H Sawa; Toru Hosoda; Sumiyo Kudoh; Y Kobayashi; Hiroyuki Aburatani; K Nagashima; Ryozo Nagai; Yoshio Yazaki; M Edward Medof; Issei Komuro
Cloning of murine glycosyl phosphatidylinositol anchor attachment protein, GPAA1.
American journal of physiology. Cell physiology 2000;279(1):C205-12.
2000: Toshihiro Utsugi; A Yoshida; Tsugiyasu Kanda; Isao Kobayashi; Masahiko Kurabayashi; Shoichi Tomono; Shoji Kawazu; Y Tajima; Ryozo Nagai
Oral administration of branched chain amino acids improves virus-induced glucose intolerance in mice.
European journal of pharmacology 2000;398(3):409-14.
2000: Ichiro Shiojima; Toru Oka; Yukio Hiroi; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Transcriptional regulation of human cardiac homeobox gene CSX1.
Biochemical and biophysical research communications 2000;272(3):749-57.
2000: Yasuyuki Sugishita; Tokiharu Takahashi; Takao Shimizu; Atsushi Yao; Koichiro Kinugawa; Kazuro Sugishita; Kenji Harada; Hiroshi Matsui; Ryozo Nagai
Expression of genes encoding vascular endothelial growth factor and its Flk-1 receptor in the chick embryonic heart.
Journal of molecular and cellular cardiology 2000;32(6):1039-51.
2000: Ikuo Yokoyama; Katsunori Yonekura; Tohru Ohtake; W Yang; W S Shin; Nobuhiro Yamada; Kuni Ohtomo; Ryozo Nagai
Coronary microangiopathy in type 2 diabetic patients: relation to glycemic control, sex, and microvascular angina rather than to coronary artery disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(6):978-85.
2000: Weidong Zhu; Yunzeng Zou; Ichiro Shiojima; Sumiyo Kudoh; Ryuichi Aikawa; Doubun Hayashi; Miho Mizukami; Haruhiro Toko; Futoshi Shibasaki; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Ca2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy.
The Journal of biological chemistry 2000;275(20):15239-45.
2000: Takayuki Shindo; Hiroki Kurihara; Koji Maemura; Yukiko Kurihara; Tomoyuki Kuwaki; T Izumida; Naoto Minamino; Kihwan Ju; Hiroyuki Morita; Yoshio Oh-hashi; Mamoru Kumada; Kenji Kangawa; Ryozo Nagai; Yoshio Yazaki
Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature.
Circulation 2000;101(19):2309-16.
2000: Hiroyuki Sumino; Tetsuya Nakamura; Tsugiyasu Kanda; Tetsuo Sakamaki; K Sato; Yuichiro Saito; J Hoshino; Toshiaki Kurashina; Z Ono; Toru Takahashi; S Ichikawa; Masahiko Kurabayashi; Ryozo Nagai
Effects of antihypertensive therapy on blood pressure and left ventricular hypertrophy in patients with severe hypertension.
Japanese heart journal 2000;41(3):339-48.
2000: Kenichi Sekiguchi; Tsugiyasu Kanda; Z Ono; Toru Tanaka; Tomoyuki Yokoyama; Y Aihara; T Toyama; Tetsuo Sakamaki; Isao Kobayashi; Masahiko Kurabayashi; Ryozo Nagai
Augmented responses of angiotensin I and II in patients with ischemic heart disease: relation to left ventricular function.
Japanese heart journal 2000;41(3):269-78.
2000: Ryozo Nagai; Yuichiro Saito; Yoshio Ohyama; H Aizawa; Tatsuo Suga; Tetsuya Nakamura; Masahiko Kurabayashi; M Kuroo
Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases.
Cellular and molecular life sciences : CMLS 2000;57(5):738-46.
2000: Ikuo Yokoyama; Katsunori Yonekura; Tohru Ohtake; H Kawamura; A Matsumoto; Yusuke Inoue; Teruhiko Aoyagi; Seiryo Sugiura; M Omata; Kuni Ohtomo; Ryozo Nagai
Role of insulin resistance in heart and skeletal muscle F-18 fluorodeoxyglucose uptake in patients with non-insulin-dependent diabetes mellitus.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2000;7(3):242-8.
2000: Ryozo Nagai; K Kowase; Masahiko Kurabayashi
Transcriptional regulation of smooth muscle phenotypic modulation.
Annals of the New York Academy of Sciences 2000;902():214-22; discussion 222-3.
2000: Keisuke Ueki; Toshimasa Yamauchi; H Tamemoto; Kazuyuki Tobe; Ritsuko Yamamoto-Honda; Yasushi Kaburagi; Yasuo Akanuma; Yoshio Yazaki; Shin Aizawa; Ryozo Nagai; Takashi Kadowaki
Restored insulin-sensitivity in IRS-1-deficient mice treated by adenovirus-mediated gene therapy.
The Journal of clinical investigation 2000;105(10):1437-45.
2000: Takayuki Shindo; Hiroki Kurihara; K Kuno; H Yokoyama; T Wada; Yukiko Kurihara; Takasuke Imai; Yuhui Wang; M Ogata; Hiroaki Nishimatsu; Nobuo Moriyama; Yoshio Oh-hashi; Hiroyuki Morita; T Ishikawa; Ryozo Nagai; Yoshio Yazaki; Kouji Matsushima
ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function.
The Journal of clinical investigation 2000;105(10):1345-52.
2000: T Ogata; Masahiko Kurabayashi; Susumu Ishikawa; Yasuo Morishita; Y i Hoshino; Kenichi Sekiguchi; Ryozo Nagai
Inducible expression of basic transcription element-binding protein 2 in proliferating smooth muscle cells at the vascular anastomotic stricture.
The Journal of thoracic and cardiovascular surgery 2000;119(5):983-9.
2000: Eiki Takimoto; T Mizuno; Fumio Terasaki; Masaki Shimoyama; Hiroaki Honda; Ichiro Shiojima; Yukio Hiroi; Toru Oka; Doubun Hayashi; Hisamura Hirai; Sumiyo Kudoh; Haruhiro Toko; K Kawamura; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Up-regulation of natriuretic peptides in the ventricle of Csx/Nkx2-5 transgenic mice.
Biochemical and biophysical research communications 2000;270(3):1074-9.
2000: Tsuyoshi Uchiyama; Masahiko Kurabayashi; Yoshio Ohyama; Toshihiro Utsugi; Nobuhiro Akuzawa; Mahito Sato; Shoichi Tomono; Shoji Kawazu; Ryozo Nagai
Hypoxia induces transcription of the plasminogen activator inhibitor-1 gene through genistein-sensitive tyrosine kinase pathways in vascular endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):1155-61.
2000: T Oka; Ichiro Shiojima; Koshiro Monzen; S Kudoh; Yukio Hiroi; Koichiro Shiokawa; M Asashima; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Fibroblast growth factor plays a critical role in SM22alpha expression during Xenopus embryogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):907-14.
2000: Masatoshi Suzuki; Nobukazu Ishizaka; Kazuhisa Tsukamoto; K Minami; Junichi Taguchi; Ryozo Nagai; Minoru Ohno
Pressurization facilitates adenovirus-mediated gene transfer into vein graft.
FEBS letters 2000;470(3):370-4.
2000: Takahiro Suzuki; K Yamaoki; O Nakajima; Tadashi Yamazaki; Y Yamada; H Akioka; Yoshio Yazaki; Ryozo Nagai
Screening for cardiac dysfunction in asymptomatic patients by measuring B-type natriuretic peptide levels.
Japanese heart journal 2000;41(2):205-14.
2000: Toshitaka Maeno; Yoshichika Sando; M Tsukagoshi; Tatsuo Suga; M Endo; Ryotaro Seki; Y Ooyama; T Yamagishi; Y Kaneko; T Kanda; Tsutomu Iwasaki; Masahiko Kurabayashi; Ryozo Nagai
Pleural amyloidosis in a patient with intractable pleural effusion and multiple myeloma.
Respirology (Carlton, Vic.) 2000;5(1):79-80.
2000: Tadanori Aizawa; Nobukazu Ishizaka; Junichi Taguchi; Ryozo Nagai; Ichiro Mori; Shiow-Shih Tang; Julie R Ingelfinger; Minoru Ohno
Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotection.
Hypertension 2000;35(3):800-6.
2000: J Kiraku; T Sugiyama; T Ashida; N Takahashi; J Fujii; Makoto Kuro-o; Ryozo Nagai
Increases in intracellular calcium of arterial smooth muscle cells in transgenic mice overexpressing Na+/H+ exchanger.
Journal of cardiovascular pharmacology 2000;35(3):511-3.
2000: Tsugiyasu Kanda; I Kobayashi; Ryozo Nagai
Cardiac interleukin-6 in ischemic myocardium.
Circulation 2000;101(8):E86.
2000: Yasuyuki Sugishita; Takao Shimizu; Atsushi Yao; Koichiro Kinugawa; Takefumi Nojiri; Kenji Harada; Hiroshi Matsui; Ryozo Nagai; Tokiharu Takahashi
Lipopolysaccharide augments expression and secretion of vascular endothelial growth factor in rat ventricular myocytes.
Biochemical and biophysical research communications 2000;268(2):657-62.
2000: Toshitaka Maeno; Yuri Maeno; Yoshichika Sando; T Takahashi; H Yarita; M Tsukagoshi; Tatsuo Suga; Masahiko Kurabayashi; Ryozo Nagai
Nuclear hypersegmentation precedes the increase in blood eosinophils in acute eosinophilic pneumonia.
Internal medicine (Tokyo, Japan) 2000;39(2):157-9.
2000: Hiroshi Morita; Ryozo Nagai
[Genetic diagnosis and cardiovascular diseases].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(2):485-94.
2000: Yuichi Kaji; Tomohiko Usui; Tetsuro Oshika; M Matsubara; Hidetoshi Yamashita; Makoto Araie; T Murata; T Ishibashi; Ryozo Nagai; Seikoh Horiuchi; Shiro Amano
Advanced glycation end products in diabetic corneas.
Investigative ophthalmology & visual science 2000;41(2):362-8.
2000: Toru Tanaka; Masahiko Kurabayashi; Yasushi Aihara; Yoshio Ohyama; Ryozo Nagai
Inducible expression of manganese superoxide dismutase by phorbol 12-myristate 13-acetate is mediated by Sp1 in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):392-401.
2000: Nobuhiro Akuzawa; Masahiko Kurabayashi; Yoshio Ohyama; Masashi Arai; Ryozo Nagai
Zinc finger transcription factor Egr-1 activates Flt-1 gene expression in THP-1 cells on induction for macrophage differentiation.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):377-84.
2000: Masashi Arai; A Yoguchi; T Takizawa; T Yokoyama; T Kanda; Masahiko Kurabayashi; Ryozo Nagai
Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca(2+)-ATPase gene transcription.
Circulation research 2000;86(1):8-14.
2000: Y Hamada; Tsugiyasu Kanda; S Ishikawa; S Imai; Ryozo Nagai; K Matsui; N Ohashi; Y Morishita
Na+/H+ exchange inhibitor reduces vascular injury caused by ischemia-reperfusion in the rat hind limb.
Research communications in molecular pathology and pharmacology 2000;107(3-4):259-67.
2000: Yuko Oyama; Masahiko Kurabayashi; Nobuhiro Akuzawa; Ryozo Nagai
Troglitazone, a PPARgamma ligand, inhibits osteopontin gene expression in human monocytes/macrophage THP-1 cells.
Journal of atherosclerosis and thrombosis 2000;7(2):77-82.
2000: Hiroshi Morita; Ryozo Nagai
[Heart failure].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():763-5.
2000: Noriaki Takama; Tetsuya Nakamura; Ryozo Nagai
[Hypertensive hypertrophic cardiomyopathy].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():749-53.
2000: Masahiko Suguta; Tetsuya Nakamura; Masahiko Kurabayashi; Ryozo Nagai
[Prognostic significance of quantification of left ventricular mass in hypertensive patients].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():740-3.
2000: Yuichiro Saito; M Kuroo; Yo-ichi Nabeshima; Ryozo Nagai
[klotho gene].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():561-5.
2000: Yuichiro Saito; Tetsuya Nakamura; Ryozo Nagai
[Vascular endothelium and vascular smooth muscle cells].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():335-9.
2000: Yuichiro Saito; Tetsuya Nakamura; Ryozo Nagai
[Coronary microcirculation].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():317-20.
2000: Ryuichi Aikawa; Issei Komuro; Ryozo Nagai
[Cardiac gene therapy].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(1):79-85.
2000: Hiroyasu Iwasa; T Itoh; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Twenty single nucleotide polymorphisms (SNPs) and their allelic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population.
Journal of human genetics 2000;45(3):182-3.
2000: Y Seta; Tsugiyasu Kanda; Tomoyuki Yokoyama; Masazumi Arai; Kenichi Sekiguchi; Toru Tanaka; Isao Kobayashi; Masahiko Kurabayashi; Ryozo Nagai
Therapy with the nonpeptide endothelin receptor antagonist 97-139 in a murine model of congestive heart failure: reduction of cardiac mass and myofiber hypertrophy.
Japanese heart journal 2000;41(1):79-85.
2000: K Kaneko; Tsugiyasu Kanda; Akira Hasegawa; Takahiro Suzuki; Isao Kobayashi; Ryozo Nagai
C-reactive protein as a prognostic marker in lymphocytic myocarditis.
Japanese heart journal 2000;41(1):41-7.
2000: Yoshinori Seko; H Nishimura; N Takahashi; Terunao Ashida; Ryozo Nagai
Serum levels of vascular endothelial growth factor and transforming growth factor-beta1 in patients with atrial fibrillation undergoing defibrillation therapy.
Japanese heart journal 2000;41(1):27-32.
2000: K Aizawa; Tetsuya Nakamura; Yoshio Ohyama; Yuichiro Saito; J Hoshino; Tsugiyasu Kanda; Hiroyuki Sumino; Ryozo Nagai
Renal artery stenosis associated with epidermal nevus syndrome.
Nephron 2000;84(1):67-70.
2000: H Sato; Tsutomu Iwasaki; Takuji Toyama; Y Kaneko; Tomio Inoue; Keigo Endo; Ryozo Nagai
Prediction of functional recovery after revascularization in coronary artery disease using (18)F-FDG and (123)I-BMIPP SPECT.
Chest 2000;117(1):65-72.
2000: Yasuo Terauchi; Naoto Kubota; H Tamemoto; H Sakura; Ryozo Nagai; Yasuo Akanuma; Satoshi Kimura; Takashi Kadowaki
Insulin effect during embryogenesis determines fetal growth: a possible molecular link between birth weight and susceptibility to type 2 diabetes.
Diabetes 2000;49(1):82-6.
2000: Tatsuo Suga; Masahiko Kurabayashi; Yoshichika Sando; Yoshio Ohyama; Toshitaka Maeno; Yuri Maeno; H Aizawa; Y Matsumura; T Kuwaki; Makoto Kuro-o; Yo-ichi Nabeshima; Ryozo Nagai
Disruption of the klotho gene causes pulmonary emphysema in mice. Defect in maintenance of pulmonary integrity during postnatal life.
American journal of respiratory cell and molecular biology 2000;22(1):26-33.
1999: Masaki Shimoyama; Doubun Hayashi; Eiki Takimoto; Yunzeng Zou; Toru Oka; Hiroki Uozumi; Sumiyo Kudoh; Futoshi Shibasaki; Yoshio Yazaki; Ryozo Nagai; Issei Komuro
Calcineurin plays a critical role in pressure overload-induced cardiac hypertrophy.
Circulation 1999;100(24):2449-54.
1999: Nobukazu Ishizaka; Akihide Nakao; N Ohishi; Masatoshi Suzuki; Tadanori Aizawa; Junichi Taguchi; Ryozo Nagai; Takao Shimizu; Minoru Ohno
Increased leukotriene A(4) hydrolase expression in the heart of angiotensin II-induced hypertensive rat.
FEBS letters 1999;463(1-2):155-9.
1999: Naoya Yahagi; Hitoshi Shimano; Alyssa H Hasty; Michiyo Amemiya-Kudo; Hiroaki Okazaki; Yoshiaki Tamura; Yoko Iizuka; Futoshi Shionoiri; Ken Ohashi; Jun-ichi Osuga; Kenji Harada; Takanari Gotoda; Ryozo Nagai; Shun Ishibashi; Nobuhiro Yamada
A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids.
The Journal of biological chemistry 1999;274(50):35840-4.
1999: Y Hamada; S Ishikawa; Tsugiyasu Kanda; S Imai; Ryozo Nagai; K Matsui; N Ohashi; Y Morishita
Sodium/hydrogen ion exchange inhibitor ameliorates ischaemia-reperfusion injuries in the rat hind limb.
International angiology : a journal of the International Union of Angiology 1999;18(4):320-6.
1999: Y Hoshino; Ryozo Nagai
[Hereditary assessment of cardiovascular disease].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():718-25.
1999: Takako Takizawa; Masashi Arai; A Yoguchi; Koichi Tomaru; Masahiko Kurabayashi; Ryozo Nagai
Transcription of the SERCA2 gene is decreased in pressure-overloaded hearts: A study using in vivo direct gene transfer into living myocardium.
Journal of molecular and cellular cardiology 1999;31(12):2167-74.
1999: Akira Hasegawa; Shunichi Toshima; A Nakano; Ryozo Nagai
[Oxidized LDL in patients with coronary heart disease and normal subjects].
Nihon rinsho. Japanese journal of clinical medicine 1999;57(12):2754-8.
1999: Takashi Nagase; Hiroki Kurihara; Yukiko Kurihara; Tomoko Aoki-Nagase; Ryozo Nagai; Yasuyoshi Ouchi
Disruption of ET-1 gene enhances pulmonary responses to methacholine via functional mechanism in knockout mice.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;87(6):2020-4.
1999: Kenichi Sekiguchi; T Yokoyama; Masahiko Kurabayashi; Fumikazu Okajima; Ryozo Nagai
Sphingosylphosphorylcholine induces a hypertrophic growth response through the mitogen-activated protein kinase signaling cascade in rat neonatal cardiac myocytes.
Circulation research 1999;85(11):1000-8.
1999: Weidong Zhu; Yunzeng Zou; Ryuichi Aikawa; K Harada; Sumiyo Kudoh; Hiroki Uozumi; Doubun Hayashi; Y Gu; Tadashi Yamazaki; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
MAPK superfamily plays an important role in daunomycin-induced apoptosis of cardiac myocytes.
Circulation 1999;100(20):2100-7.
1999: Ichiro Shiojima; M Aikawa; Jun-Ichi Suzuki; Yoshio Yazaki; Ryozo Nagai
Embryonic smooth muscle myosin heavy chain SMemb is expressed in pressure-overloaded cardiac fibroblasts.
Japanese heart journal 1999;40(6):803-18.
1999: Jun-Ichi Suzuki; WS Shin; Ryoichi Shimamoto; Tadashi Yamazaki; Taeko Tsuji; Yuji Murakawa; Toshiaki Nakajima; Teruhiko Toyo-Oka; J Nishikawa; K Ohotomo; Ryozo Nagai; Masao Omata
Clinical implication of left precordial T wave inversions in the presence of complete right bundle branch block.
Japanese heart journal 1999;40(6):745-53.
1999: Keiko Kawai-Kowase; Masahiko Kurabayashi; Y i Hoshino; Yoshio Ohyama; Ryozo Nagai
Transcriptional activation of the zinc finger transcription factor BTEB2 gene by Egr-1 through mitogen-activated protein kinase pathways in vascular smooth muscle cells.
Circulation research 1999;85(9):787-95.
1999: Y Aihara; M Kurabayashi; M Arai; Larry Kedes; Ryozo Nagai
Molecular cloning of rabbit CARP cDNA and its regulated expression in adriamycin-cardiomyopathy.
Biochimica et biophysica acta 1999;1447(2-3):318-24.
1999: Takahiro Suzuki; H Katoh; Ryozo Nagai
Biochemical diagnosis of aortic dissection: from bench to bedside.
Japanese heart journal 1999;40(5):527-34.
1999: Yoshinori Seko; N Takahashi; H Sabe; Kazuyuki Tobe; Takashi Kadowaki; Ryozo Nagai
Hypoxia induces activation and subcellular translocation of focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes.
Biochemical and biophysical research communications 1999;262(1):290-6.
1999: Shitoshi Hiroi; H Harada; Hirofumi Nishi; M Satoh; Ryozo Nagai; Akinori Kimura
Polymorphisms in the SOD2 and HLA-DRB1 genes are associated with nonfamilial idiopathic dilated cardiomyopathy in Japanese.
Biochemical and biophysical research communications 1999;261(2):332-9.
1999: Hironosuke Sakamoto; Tetsuo Sakamaki; Tsugiyasu Kanda; Masahiko Kurabayashi; Ryozo Nagai; J Fujii
Loculated pericardial effusion due to congestive heart failure: an unusual case of vanishing tumor--a case report.
Angiology 1999;50(8):683-7.
1999: S Saito; Ryuichi Aikawa; Ichiro Shiojima; Ryozo Nagai; Yoshio Yazaki; Issei Komuro
Endothelin-1 induces expression of fetal genes through the interleukin-6 family of cytokines in cardiac myocytes.
FEBS letters 1999;456(1):103-7.
1999: N Watanabe; Masahiko Kurabayashi; Y Shimomura; Keiko Kawai-Kowase; Y i Hoshino; Ichiro Manabe; M Watanabe; M Aikawa; Makoto Kuro-o; Takahiro Suzuki; Y Yazaki; Ryozo Nagai
BTEB2, a Krüppel-like transcription factor, regulates expression of the SMemb/Nonmuscle myosin heavy chain B (SMemb/NMHC-B) gene.
Circulation research 1999;85(2):182-91.
1999: Hiroki Kurihara; Yukiko Kurihara; Ryozo Nagai; Yoshio Yazaki
Endothelin and neural crest development.
Cellular and molecular biology (Noisy-le-Grand, France) 1999;45(5):639-51.
1999: Norimichi Koitabashi; T Utsugi; Ryotaro Seki; Ei-ichi Okamoto; Yoshichika Sando; Y Kaneko; Ryozo Nagai
Biopsy-proven cardiomyopathy in heterozygous Fabry's disease.
Japanese circulation journal 1999;63(7):572-5.
1999: A Yoshida; Tsugiyasu Kanda; Hironosuke Sakamoto; H Masuda; T Iwasaki; T Nakajima; Isao Kobayashi; Ryozo Nagai
Sudden death with malignant hemangioendothelioma originating in the pericardium--a case report.
Angiology 1999;50(7):607-11.
1999: Yuichiro Saito; M Kuroo; Yo-ichi Nabeshima; Ryozo Nagai
[The protective role of Klotho gene on vascular endothelium].
Nihon rinsho. Japanese journal of clinical medicine 1999;57(7):1514-8.
1999: Y Ito; S Imai; G Ui; M Nakano; K Imai; H Kamiyama; F Naganuma; K Matsui; N Ohashi; Ryozo Nagai
A Na+-H+ exchange inhibitor (SM-20550) protects from microvascular deterioration and myocardial injury after reperfusion.
European journal of pharmacology 1999;374(3):355-66.
1999: J Kiraku; Tetsuya Nakamura; T Sugiyama; N Takahashi; Makoto Kuro-o; J Fujii; Ryozo Nagai
Dietary salt loading increases nitric oxide synthesis in transgenic mice overexpressing sodium-proton exchanger.
Japanese journal of pharmacology 1999;80(2):181-3.
1999: Tomoyuki Yokoyama; Kenichi Sekiguchi; Toru Tanaka; Koichi Tomaru; Masashi Arai; Takahiro Suzuki; Ryozo Nagai
Angiotensin II and mechanical stretch induce production of tumor necrosis factor in cardiac fibroblasts.
The American journal of physiology 1999;276(6 Pt 2):H1968-76.
1999: Wataru Okumura; Tsutomu Iwasaki; T Ueda; Ryotaro Seki; A Miyajima; Takashi Hatori; H Sato; Takuji Toyama; Takahiro Suzuki; K Matsubara; H Otake; K Aoyagi; Tomio Inoue; Keigo Endo; Ryozo Nagai
[Usefulness of 18F-FDG PET for diagnosis of cardiac sarcoidosis].
Kaku igaku. The Japanese journal of nuclear medicine 1999;36(4):341-8.
1999: M Tanehata; Hitoshi Adachi; Shigeru Oshima; Koichi Taniguchi; H Itoh; Akira Hasegawa; Ryozo Nagai
The time from anaerobic threshold (AT) to respiratory compensation point reflects the rate of aerobic and anaerobic metabolism after the AT in chronic heart failure patients.
Japanese circulation journal 1999;63(4):274-7.
1999: Hironosuke Sakamoto; Tetsuo Sakamaki; T Tani; Y Sugai; Tetsuya Nakamura; Z Ono; Tsugiyasu Kanda; Masahiko Kurabayashi; Ryozo Nagai
"White coat effect" induced by therapist's presence during speech therapy for stroke rehabilitation: a single case study.
Archives of physical medicine and rehabilitation 1999;80(4):470-2.
1999: Takuji Toyama; Y Aihara; Tsutomu Iwasaki; Akira Hasegawa; Takahiro Suzuki; Ryozo Nagai; Keigo Endo; Hiroshi Hoshizaki; Shigeru Oshima; Koichi Taniguchi
Cardiac sympathetic activity estimated by 123I-MIBG myocardial imaging in patients with dilated cardiomyopathy after beta-blocker or angiotensin-converting enzyme inhibitor therapy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(2):217-23.
1999: K Kaneko; Tsugiyasu Kanda; Y Yamauchi; Akira Hasegawa; T Iwasaki; Masazumi Arai; Takahiro Suzuki; Isao Kobayashi; Ryozo Nagai
C-Reactive protein in dilated cardiomyopathy.
Cardiology 1999;91(4):215-9.
1999: Hiroyuki Sumino; Tsugiyasu Kanda; T Nakamura; Tetsuo Sakamaki; Hironosuke Sakamoto; K Sato; Shoichi Tange; Shuichi Ichikawa; Ryozo Nagai
Steroid therapy is effective in a young patient with an inflammatory abdominal aortic aneurysm.
Journal of medicine 1999;30(1-2):67-74.
1999: Tsugiyasu Kanda; Hiroto Koike; Masazumi Arai; Janet E Wilson; Christopher M Carthy; Dawei Yang; Bruce M McManus; Ryozo Nagai; Isao Kobayashi
Increased severity of viral myocarditis in mice lacking lymphocyte maturation.
International journal of cardiology 1999;68(1):13-22.
1999: Tomoyuki Yokoyama; Masashi Arai; Kenichi Sekiguchi; Toru Tanaka; Tsugiyasu Kanda; Takahiro Suzuki; Ryozo Nagai
Tumor necrosis factor-alpha decreases the phosphorylation levels of phospholamban and troponin I in spontaneously beating rat neonatal cardiac myocytes.
Journal of molecular and cellular cardiology 1999;31(1):261-73.
1999: Tsugiyasu Kanda; M Nakano; Tomoyuki Yokoyama; Y Hoshino; F Okajima; Toru Tanaka; Yuichiro Saito; Ryozo Nagai; Isao Kobayashi
Heat stress aggravates viral myocarditis in mice.
Life sciences 1999;64(2):93-101.
1999: Tetsuya Nakamura; R Igarashi; Toshiaki Kurashina; Yuichiro Saito; J Hoshino; Hiroyuki Sumino; Hironosuke Sakamoto; Ryozo Nagai
Lecithinized superoxide dismutase induces vasodilation; evidence of direct contribution of superoxide anions to modulating vascular tone.
Life sciences 1999;64(4):PL65-70.
1998: Tetsuya Nakamura; Toshiaki Kurashina; Yuichiro Saito; Hiroyuki Sumino; Nobuhiro Akuzawa; H Aizawa; Hironosuke Sakamoto; Z Ono; Ryozo Nagai
ET(A) receptor antagonist ameliorates nephrosclerosis and left ventricular hypertrophy induced in rat by prolonged inhibition of nitric oxide synthesis.
Hypertension research : official journal of the Japanese Society of Hypertension 1998;21(4):251-7.
1998: J Hoshino; Tetsuya Nakamura; Toshiaki Kurashina; Yuichiro Saito; Hiroyuki Sumino; Z Ono; Hironosuke Sakamoto; K Kowase; Ryozo Nagai
Antagonism of ANG II type 1 receptors protects the endothelium during the early stages of renal hypertension in rats.
The American journal of physiology 1998;275(6 Pt 2):R1950-7.
1998: M Tanehata; Hitoshi Adachi; Shigeru Oshima; Koichi Taniguchi; H Itoh; Akira Hasegawa; Ryozo Nagai
Improved oxygen utilization during mild exercise in heart failure.
Japanese circulation journal 1998;62(10):741-4.
1998: T Itoh; Toshihiro Tanaka; Ryozo Nagai; K Kikuchi; Seishi Ogawa; S Okada; S Yamagata; K Yano; Yoshio Yazaki; Yusuke Nakamura
Genomic organization and mutational analysis of KVLQT1, a gene responsible for familial long QT syndrome.
Human genetics 1998;103(3):290-4.
1998: H Aizawa; Yuichiro Saito; Tetsuya Nakamura; M Inoue; T Imanari; Yoshio Ohyama; Y Matsumura; Hiroaki Masuda; S Oba; Naobumi Mise; Kenjiro Kimura; A Hasegawa; Masahiko Kurabayashi; Makoto Kuro-o; Yo-ichi Nabeshima; Ryozo Nagai
Downregulation of the Klotho gene in the kidney under sustained circulatory stress in rats.
Biochemical and biophysical research communications 1998;249(3):865-71.
1998: Takahiro Suzuki; D Hayashi; Tadashi Yamazaki; T Mizuno; Y Kanda; Issei Komuro; Masahiko Kurabayashi; K Yamaoki; K Mitani; H Hirai; Ryozo Nagai; Yoshio Yazaki
Elevated B-type natriuretic peptide levels after anthracycline administration.
American heart journal 1998;136(2):362-3.
1998: Yuichiro Saito; T Yamagishi; Tetsuya Nakamura; Yoshio Ohyama; H Aizawa; Tatsuo Suga; Y Matsumura; Hiroaki Masuda; Masahiko Kurabayashi; Makoto Kuro-o; Yo-ichi Nabeshima; Ryozo Nagai
Klotho protein protects against endothelial dysfunction.
Biochemical and biophysical research communications 1998;248(2):324-9.
1998: T Matsuse; Eijiro Ohga; S Teramoto; Masashi Fukayama; Ryozo Nagai; Seikoh Horiuchi; Y Ouchi
Immunohistochemical localisation of advanced glycation end products in pulmonary fibrosis.
Journal of clinical pathology 1998;51(7):515-9.
1998: Hironosuke Sakamoto; Tetsuo Sakamaki; Tsugiyasu Kanda; Y Ito; Hiroyuki Sumino; H Masuda; Y Ohyama; Z Ono; Masahiko Kurabayashi; Isao Kobayashi; Ryozo Nagai
The somatostatin analog, octreotide, inhibits in vitro outgrowth of smooth muscle cells from canine coronary and carotid atherosclerotic plaque tissues.
Research communications in molecular pathology and pharmacology 1998;101(1):25-34.
1998: Takahiro Suzuki; Ryozo Nagai; Yoshio Yazaki
Mechanisms of transcriptional regulation of gene expression in smooth muscle cells.
Circulation research 1998;82(12):1238-42.
1998: M Inoue; Tsugiyasu Kanda; Masazumi Arai; B M McManus; Takahiro Suzuki; Isao Kobayashi; Ryozo Nagai
Impaired expression of atrial natriuretic peptide in diabetic rats with myocardial infarction.
Research communications in molecular pathology and pharmacology 1998;100(3):327-38.
1998: T Iwami; Tetsuya Nakamura; N Niwamae; T Yamagishi; Toshihiro Utsugi; Ryozo Nagai
Pre-clinical Cushing's syndrome with body weight loss and normal circadian rhythm of blood pressure.
Internal medicine (Tokyo, Japan) 1998;37(6):528-33.
1998: Takashi Hatori; Tsutomu Iwasaki; Ryotaro Seki; T Yamagishi; Takuji Toyama; Y Kaneko; Akira Hasegawa; Ryozo Nagai
[Technetium-99m (V) dimercaptosuccinic acid myocardial scintigraphy in a 74-year-old woman with congestive heart failure].
Journal of cardiology 1998;31(6):381-4.
1998: Nobuhiro Akuzawa; Tetsuya Nakamura; Toshiaki Kurashina; Yuichiro Saito; J Hoshino; Hironosuke Sakamoto; Hiroyuki Sumino; Z Ono; Ryozo Nagai
Antihypertensive agents prevent nephrosclerosis and left ventricular hypertrophy induced in rats by prolonged inhibition of nitric oxide synthesis.
American journal of hypertension 1998;11(6 Pt 1):697-707.
1998: Akira Matsumori; N Ohashi; Koji Hasegawa; Shigetake Sasayama; T Eto; T Imaizumi; T Izumi; K Kawamura; M Kawana; A Kimura; A Kitabatake; Masunori Matsuzaki; Ryozo Nagai; H Tanaka; M Hiroe; M Hori; H Inoko; Y Seko; M Sekiguchi; K Shimotohno; Y Sugishita; N Takeda; K Takihara; Mari Tanaka; M Yokoyama
Hepatitis C virus infection and heart diseases: a multicenter study in Japan.
Japanese circulation journal 1998;62(5):389-91.
1998: Toshiyuki Takahashi; Tsugiyasu Kanda; H Sumino; M Inoue; K Sato; T Sakamaki; I Kobayashi; A Iwamoto; Ryozo Nagai
Type V phosphodiesterase inhibition modulates endogenous immunoreactivities of endothelin-1 and endothelial nitric oxide synthase in pulmonary arteries in rats with monocrotaline-induced pulmonary hypertension.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1998;197(6):319-28.
1998: T Itoh; Toshihiro Tanaka; Ryozo Nagai; T Kamiya; T Sawayama; T Nakayama; Hitonobu Tomoike; Harumizu Sakurada; Yoshio Yazaki; Yusuke Nakamura
Genomic organization and mutational analysis of HERG, a gene responsible for familial long QT syndrome.
Human genetics 1998;102(4):435-9.
1998: Tadashi Yamazaki; Issei Komuro; Sumiyo Kudoh; Yunzeng Zou; Ryozo Nagai; Ryuichi Aikawa; Hiroki Uozumi; Yoshio Yazaki
Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy.
Circulation research 1998;82(4):430-7.
1998: T Shiraki-Iida; H Aizawa; Y Matsumura; S Sekine; A Iida; Hideharu Anazawa; Ryozo Nagai; Makoto Kuro-o; Yo-ichi Nabeshima
Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein.
FEBS letters 1998;424(1-2):6-10.
1998: Ryozo Nagai; Y i Hoshino
[Molecular genetics of cardiovascular diseases].
Rinsho byori. The Japanese journal of clinical pathology 1998;46(3):249-57.
1998: Tsutomu Iwasaki; T Iwasaki; Noboru Oriuchi; Katsuaki Endou; Takahiro Suzuki; H Katoh; Ryozo Nagai
[Radioimmunoimaging of aortic dissection and acute bowel infarction with radiolabeled [correction of radioiodinated] murine antismooth muscle myosin antibody.
Journal of cardiology 1998;31(3):182-3.
1998: Masashi Arai; Koichi Tomaru; Takako Takizawa; Kenichi Sekiguchi; Tomoyuki Yokoyama; Takahiro Suzuki; Ryozo Nagai
Sarcoplasmic reticulum genes are selectively down-regulated in cardiomyopathy produced by doxorubicin in rabbits.
Journal of molecular and cellular cardiology 1998;30(2):243-54.
1998: H Sumino; K Sato; T Sakamaki; H Masuda; T Nakamura; Tsugiyasu Kanda; Ryozo Nagai
Decreased basal production of nitric oxide in patients with heart disease.
Chest 1998;113(2):317-22.
1998: Tsugiyasu Kanda; Shinya Kogure; M Nara; S Tsukui; Toshihiro Utsugi; Shoichi Tomono; Shoji Kawazu; Ryozo Nagai; Isao Kobayashi
Combination of OK432 and human interferon-alpha for treating viral-induced diabetes mellitus in mice.
European journal of pharmacology 1998;342(2-3):297-302.
1998: Y Matsumura; H Aizawa; T Shiraki-Iida; Ryozo Nagai; Makoto Kuro-o; Yo-ichi Nabeshima
Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein.
Biochemical and biophysical research communications 1998;242(3):626-30.
1998: Kenichi Tamama; Tsugiyasu Kanda; M Osada; Ryozo Nagai; Takahiro Suzuki; Isao Kobayashi
Detection of left ventricular enlargement by electrocariography.
Journal of medicine 1998;29(3-4):231-6.
1998: Toshiyuki Takahashi; Tsugiyasu Kanda; M Inoue; H Sumino; I Kobayashi; A Iwamoto; Ryozo Nagai
Endothelin converting enzyme inhibitor protects development of right ventricular overload and medial thickening of pulmonary arteries in rats with monocrotaline-induced pulmonary hypertension.
Life sciences 1998;63(10):PL137-43.
1998: Tsugiyasu Kanda; Toshihiro Utsugi; Shoji Kawazu; Janet E Wilson; Dawei Yang; A Suarez; Bruce M McManus; Ryozo Nagai; Isao Kobayashi
Induction of virus-induced IDDM in virus resistant mice without lymphocyte maturation.
Life sciences 1998;63(1):33-40.
1998: Naobumi Mise; Kenjiro Kimura; Ryozo Nagai; Shigeyoshi Ohba; Naoe Suzuki; Kazuhisa Miyashita; Arinobu Tojo; Atsuo Goto; Masao Omata
Mesangial expression of a nonmuscle myosin heavy chain, SMemb, is associated with glomerular sclerosis and renal prognosis in IgA nephropathy.
Nephron 1998;78(3):284-9.
1998: H Aizawa; Akira Hasegawa; Masashi Arai; F Naganuma; M Hatori; Tsugiyasu Kanda; T Suzuki; K Murata; Y Satoh; Susumu Ishikawa; Yasuo Morishita; Ryozo Nagai
Bilateral coronary ostial stenosis and aortic regurgitation due to syphilitic aortitis.
Internal medicine (Tokyo, Japan) 1998;37(1):56-9.
1998: Tetsuya Nakamura; A M Alberola; F J Salazar; Yuichiro Saito; Toshiaki Kurashina; Joey P Granger; Ryozo Nagai
Effects of renal perfusion pressure on renal interstitial hydrostatic pressure and Na+ excretion: role of endothelium-derived nitric oxide.
Nephron 1998;78(1):104-11.
1998: T Yamazaki; Issei Komuro; Yunzeng Zou; Sumiyo Kudoh; Ichiro Shiojima; T Mizuno; Yukio Hiroi; Ryozo Nagai; Yoshio Yazaki
Efficient inhibition of the development of cardiac remodeling by a long-acting calcium antagonist amlodipine.
Hypertension 1998;31(1):32-8.
1997: Makoto Kuro-o; Y Matsumura; H Aizawa; H Kawaguchi; T Suga; T Utsugi; Y Ohyama; Masahiko Kurabayashi; T Kaname; E Kume; H Iwasaki; A Iida; T Shiraki-Iida; S Nishikawa; Ryozo Nagai; Yo-ichi Nabeshima
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
Nature 1997;390(6655):45-51.
1997: Ichiro Manabe; Masahiko Kurabayashi; Yoshiharu Shimomura; Makoto Kuro-o; Nobukazu Watanabe; Masahiko Watanabe; M Aikawa; Takahiro Suzuki; Yoshio Yazaki; Ryozo Nagai
Isolation of the embryonic form of smooth muscle myosin heavy chain (SMemb/NMHC-B) gene and characterization of its 5'-flanking region.
Biochemical and biophysical research communications 1997;239(2):598-605.
1997: K Kowase; Tetsuya Nakamura; Wataru Okumura; Ei-ichi Okamoto; E Yamaguchi; H Sato; Masashi Arai; S Imai; Akira Hasegawa; Ryozo Nagai
Novel deletion on the short arm of chromosome 17 in a patient with multiple cardiac anomalies.
Japanese circulation journal 1997;61(10):882-5.
1997: Satoko Yamada; Hidekazu Nishigori; H Onda; T Utsugi; T Yanagawa; T Maruyama; Kazumichi Onigata; K Nagashima; Ryozo Nagai; A Morikawa; Toshiyuki Takeuchi; Jun Takeda
Identification of mutations in the hepatocyte nuclear factor (HNF)-1 alpha gene in Japanese subjects with IDDM.
Diabetes 1997;46(10):1643-7.
1997: Tetsuya Nakamura; Yuichiro Saito; T Kato; Hiroyuki Sumino; J Hoshino; Z Ono; Tetsuo Sakamaki; Ryozo Nagai
Flow-mediated vasodilation of a conduit artery in relation to downstream peripheral tissue blood flow during reactive hyperemia in humans.
Japanese circulation journal 1997;61(9):772-80.
1997: Yoshie Sawada; Masayuki Suda; H Yokoyama; Tsugiyasu Kanda; T Sakamaki; Shigeyasu Tanaka; Ryozo Nagai; S Abe; Toshiyuki Takeuchi
Stretch-induced hypertrophic growth of cardiocytes and processing of brain-type natriuretic peptide are controlled by proprotein-processing endoprotease furin.
The Journal of biological chemistry 1997;272(33):20545-54.
1997: Akinori Kimura; H Harada; J E Park; Hirofumi Nishi; M Satoh; Megumi Takahashi; Shitoshi Hiroi; Taishi Sasaoka; N Ohbuchi; Takeyuki Nakamura; T Koyanagi; T H Hwang; J A Choo; K S Chung; A Hasegawa; Ryozo Nagai; O Okazaki; H Nakamura; M Matsuzaki; T Sakamoto; H Toshima; Y Koga; T Imaizumi; T Sasazuki
Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy.
Nature genetics 1997;16(4):379-82.
1997: Hironosuke Sakamoto; Tetsuo Sakamaki; Tsugiyasu Kanda; Y Hirao; Y Ohyama; K Ogishi; M Negishi; H Masuda; Hiroyuki Sumino; Yoshie Sawada; Z Ono; Isao Kobayashi; Ryozo Nagai
Immunosuppressive drugs inhibit the production of interleukin-6 and interleukin-8 in cultured cardiac myxoma cells.
Research communications in molecular pathology and pharmacology 1997;97(1):60-6.
1997: K Kaneko; Tsugiyasu Kanda; Tomoyuki Yokoyama; Y Nakazato; T Iwasaki; Isao Kobayashi; Ryozo Nagai
Expression of interleukin-6 in the ventricles and coronary arteries of patients with myocardial infarction.
Research communications in molecular pathology and pharmacology 1997;97(1):3-12.
1997: Tatsuya Iso; Masashi Arai; A Wada; K Kogure; Takahiro Suzuki; Ryozo Nagai
Humoral factor(s) produced by pressure overload enhance cardiac hypertrophy and natriuretic peptide expression.
The American journal of physiology 1997;273(1 Pt 2):H113-8.
1997: M Aikawa; Yasunari Sakomura; M Ueda; Kenjiro Kimura; Ichiro Manabe; Sugao Ishiwata; N Komiyama; H Yamaguchi; Yoshio Yazaki; Ryozo Nagai
Redifferentiation of smooth muscle cells after coronary angioplasty determined via myosin heavy chain expression.
Circulation 1997;96(1):82-90.
1997: Takahiro Suzuki; Tsugiyasu Kanda; H Nagaoka; S Kubota; T Iizuka; Ryozo Nagai; Isao Kobayashi
Predictive value of left ventricular response to exercise in patients with dilated cardiomyopathy--assessment by radionuclide ventriculography.
Angiology 1997;48(6):497-502.
1997: Tetsuya Nakamura; Yoshio Ohyama; Hiroaki Masuda; Toshiaki Kurashina; Yuichiro Saito; T Kato; Hiroyuki Sumino; K Sato; Tetsuo Sakamaki; A Sasaki; Ryozo Nagai
Chronic blockade of nitric oxide synthesis increases urinary endothelin-1 excretion.
Journal of hypertension 1997;15(4):373-81.
1997: Nobuhiro Akuzawa; Tetsuya Nakamura; A Tanaka; S Ikeda; T Fukuda; Tetsuo Sakamaki; Ryozo Nagai
Transient hypertension due to adrenal hemorrhage in a patient with von Recklinghausen's disease.
Internal medicine (Tokyo, Japan) 1997;36(4):289-92.
1997: H Sato; Takuji Toyama; Y Kaneko; Ryozo Nagai; Katsumi Tomiyoshi; Tomio Inoue; Keigo Endo; N Ota; N Kanazawa; Takahiro Suzuki
[The usefulness of 18F-FDG SPECT imaging in evaluating myocardial viability].
Kaku igaku. The Japanese journal of nuclear medicine 1997;34(3):137-43.
1997: H Nagaoka; Naoki Isobe; S Kubota; T Iizuka; S Imai; Takahiro Suzuki; Ryozo Nagai
Comparison of adenosine, dobutamine, and exercise radionuclide ventriculography in the detection of coronary artery disease.
Cardiology 1997;88(2):180-8.
1997: Toshihiro Tanaka; Ryozo Nagai; Hitonobu Tomoike; S Takata; K Yano; K Yabuta; N Haneda; O Nakano; A Shibata; T Sawayama; H Kasai; Yoshio Yazaki; Yusuke Nakamura
Four novel KVLQT1 and four novel HERG mutations in familial long-QT syndrome.
Circulation 1997;95(3):565-7.
1997: Akira Hasegawa; M Hatori; M Amano; T Iijima; Hitoshi Adachi; E Yamaguchi; T Fukuda; K Murata; Ryozo Nagai
Adequacy of pacing rate during exercise in rate responsive ventricular pacing.
Pacing and clinical electrophysiology : PACE 1997;20(2 Pt 1):307-12.
1997: Yoshie Sawada; M Inoue; Tsugiyasu Kanda; T Sakamaki; Shigeyasu Tanaka; N Minamino; Ryozo Nagai; Toshiyuki Takeuchi
Co-elevation of brain natriuretic peptide and proprotein-processing endoprotease furin after myocardial infarction in rats.
FEBS letters 1997;400(2):177-82.
1997: Hiroyuki Sumino; Tsugiyasu Kanda; Isao Kobayashi; Hironosuke Sakamoto; K Sato; Tetsuo Sakamaki; Toshio Fukuda; Shuichi Ichikawa; Ryozo Nagai
Reduced serum T3 level in a patient with nodular goiter and cardiac myxoma.
Journal of medicine 1997;28(5-6):319-24.
1997: Y Seta; Tsugiyasu Kanda; Tomoyuki Yokoyama; Isao Kobayashi; Takahiro Suzuki; Ryozo Nagai
Effect of amrinone on murine viral myocarditis.
Research communications in molecular pathology and pharmacology 1997;95(1):57-66.
1997: Chiaki Ishii; Shoji Kawazu; Toshihiro Utsugi; Y Ito; T Ohno; N Kato; Shoichi Tomono; Ryozo Nagai; Kajuro Komeda
Change of plasma 1,5-anhydro-D-glucitol levels after the onset of diabetes in spontaneous diabetes prone BB/Wor/(/)Tky rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1997;29(1):9-11.
1996: J Suzuki; M Isobe; M Aikawa; M Kawauchi; Ichiro Shiojima; N Kobayashi; Arinobu Tojo; T Suzuki; K Kimura; Toshiro Nishikawa; T Sakai; M Sekiguchi; Y Yazaki; Ryozo Nagai
Nonmuscle and smooth muscle myosin heavy chain expression in rejected cardiac allografts. A study in rat and monkey models.
Circulation 1996;94(5):1118-24.
1996: Masashi Arai; T Suzuki; Ryozo Nagai
Sarcoplasmic reticulum genes are upregulated in mild cardiac hypertrophy but downregulated in severe cardiac hypertrophy induced by pressure overload.
Journal of molecular and cellular cardiology 1996;28(8):1583-90.
1996: K Kimura; Naoe Suzuki; Shigeyoshi Ohba; Ryozo Nagai; J Hiroi; Naobumi Mise; Arinobu Tojo; A Nagaoka; Yasunobu Hirata; Atsuo Goto; Y Yazaki; Masao Omata
Hypertensive glomerular damage as revealed by the expression of alpha-smooth muscle actin and non-muscle myosin.
Kidney international. Supplement 1996;55():S169-72.
1996: Takuji Toyama; Hiroshi Hoshizaki; N Isobe; S Ohshima; Koichi Taniguchi; Y Suzuki; T Suzuki; Ryozo Nagai; Keigo Endo
[The regional wall motion and the myocardial fatty acid metabolism at hibernating myocardium].
Kaku igaku. The Japanese journal of nuclear medicine 1996;33(6):607-15.
1996: M Watanabe; Yasunari Sakomura; Masahiko Kurabayashi; Ichiro Manabe; M Aikawa; Makoto Kuro-o; T Suzuki; Y Yazaki; Ryozo Nagai
Structure and characterization of the 5'-flanking region of the mouse smooth muscle myosin heavy chain (SM1/2) gene.
Circulation research 1996;78(6):978-89.
1996: K Sato; Hiroyuki Sumino; Tetsuo Sakamaki; H Sakamoto; T Nakamura; Z Ono; Ryozo Nagai
Lack of inhibitory effect of dexamethasone on exhalation of nitric oxide by healthy humans.
Internal medicine (Tokyo, Japan) 1996;35(5):356-61.
1996: J Hiroi; K Kimura; M Aikawa; Arinobu Tojo; Y Suzuki; T Nagamatsu; Masao Omata; Y Yazaki; Ryozo Nagai
Expression of a nonmuscle myosin heavy chain in glomerular cells differentiates various types of glomerular disease in rats.
Kidney international 1996;49(5):1231-41.
1996: Tsugiyasu Kanda; J E McManus; Ryozo Nagai; S Imai; T Suzuki; Dawei Yang; Bruce M McManus; Isao Kobayashi
Modification of viral myocarditis in mice by interleukin-6.
Circulation research 1996;78(5):848-56.
1996: H Nagaoka; S Kubota; T Iizuka; S Imai; Ryozo Nagai
Relation between depressed cardiac response to exercise and autonomic nervous activity in mildly symptomatic patients with idiopathic dilated cardiomyopathy.
Chest 1996;109(4):925-32.
1996: T Suzuki; H Katoh; M Watanabe; Masahiko Kurabayashi; K Hiramori; S Hori; M Nobuyoshi; H Tanaka; K Kodama; H Sato; Shin Suzuki; Y Tsuchio; Y Yazaki; Ryozo Nagai
Novel biochemical diagnostic method for aortic dissection. Results of a prospective study using an immunoassay of smooth muscle myosin heavy chain.
Circulation 1996;93(6):1244-9.
1996: T Nakajima; Y Kaneko; Y Taniguchi; Ryozo Nagai
[Long QT syndrome].
Nihon rinsho. Japanese journal of clinical medicine 1996;54(3):776-81.
1996: T Suzuki; H S Kim; Masahiko Kurabayashi; H Hamada; H Fujii; M Aikawa; M Watanabe; N Watanabe; Yasunari Sakomura; Y Yazaki; Ryozo Nagai
Preferential differentiation of P19 mouse embryonal carcinoma cells into smooth muscle cells. Use of retinoic acid and antisense against the central nervous system-specific POU transcription factor Brn-2.
Circulation research 1996;78(3):395-404.
1996: T Takahashi; Tsugiyasu Kanda; M Inoue; T Suzuki; Isao Kobayashi; K Kodama; Ryozo Nagai
A selective type V phosphodiesterase inhibitor, E4021, protects the development of right ventricular overload and medial thickening of pulmonary arteries in a rat model of pulmonary hypertension.
Life sciences 1996;59(23):PL 371-7.
1996: T Takahashi; Tsugiyasu Kanda; S Imai; T Suzuki; Isao Kobayashi; Ryozo Nagai
Amlodipine inhibits the development of right ventricular hypertrophy and medial thickening of pulmonary arteries in a rat model of pulmonary hypertension.
Research communications in molecular pathology and pharmacology 1996;91(1):17-32.
1996: Tsugiyasu Kanda; Hironosuke Sakamoto; Bruce M McManus; Tetsuo Sakamaki; Ryozo Nagai; T Suzuki; Isao Kobayashi
Interleukin-6 secreted from human myxoma reduces murine viral myocarditis.
Life sciences 1996;58(20):1705-12.
1996: T Suzuki; M Aikawa; Makoto Kuro-o; M Watanabe; K Kimura; Y Yazaki; Ryozo Nagai
Presence of contractile-type smooth muscle cells in the endocardium.
Cardiology 1996;87(1):23-7.
1996: E Okamoto; T Suzuki; M Aikawa; K Imataka; J Fujii; Makoto Kuro-o; K Nakahara; A Hasegawa; Y Yazaki; Ryozo Nagai
Diversity of the synthetic-state smooth-muscle cells proliferating in mechanically and hemodynamically injured rabbit arteries.
Laboratory investigation; a journal of technical methods and pathology 1996;74(1):120-8.
1995: Tetsuo Sakamaki; K Sato; M Mochida; Y Saito; Y Oyama; Ryozo Nagai; M Ikeno; T Ishikawa
Synthetic N omega-hydroxy-L-arginine causes endothelium-dependent vascular relaxation both in vitro and in vivo.
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 1995;31(6):439-43.
1995: Y Oyama; Tetsuo Sakamaki; H Masuda; Hiroyuki Sumino; M Mochida; K Sakamoto; T Nakamura; K Sato; Z Ono; Ryozo Nagai
[Effect of lipopolysaccharide on nitric oxide synthase family (neural NOS, endothelial NOS and inducible NOS)].
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 1995;31(6):435-6.
1995: Y Suzuki; Takuji Toyama; Tsugiyasu Kanda; J Tsukagoshi; N Isobe; H Nagaoka; S Kubota; T Iizuka; S Imai; Ryozo Nagai
[Prognostic significance of 123I-metaiodobenzylguanidine scintigraphy in dilated cardiomyopathy].
Kaku igaku. The Japanese journal of nuclear medicine 1995;32(11):1207-15.
1995: Yoshinori Seko; Masahiko Azuma; Hideo Yagita; K Okumura; H Hirai; Ryozo Nagai; Y Yazaki
Perforin-positive leukemic cell infiltration in the heart of a patient with T-cell prolymphocytic leukemia.
Internal medicine (Tokyo, Japan) 1995;34(8):782-4.
1995: K Kimura; Ryozo Nagai; T Sakai; M Aikawa; Makoto Kuro-o; N Kobayashi; Isao Shirato; Tadashi Inagami; M Oshi; Naoe Suzuki
Diversity and variability of smooth muscle phenotypes of renal arterioles as revealed by myosin isoform expression.
Kidney international 1995;48(2):372-82.
1995: Yukiko Kurihara; Hiroki Kurihara; Hiromi Oda; Koji Maemura; Ryozo Nagai; T Ishikawa; Y Yazaki
Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1.
The Journal of clinical investigation 1995;96(1):293-300.
1995: Issei Komuro; Tadashi Yamazaki; Y Katoh; Kazuyuki Tobe; Takashi Kadowaki; Ryozo Nagai; Y Yazaki
Protein kinase cascade activated by mechanical stress in cardiocytes: possible involvement of angiotensin II.
European heart journal 1995;16 Suppl C():8-11.
1995: Ryozo Nagai; Makoto Kuro-o; M Aikawa; M Watanabe; T Suzuki; Y Yazaki
[Smooth muscle myosin heavy chain expression in the arterial wall; a new viewpoint for vascular pathology].
Rinsho byori. The Japanese journal of clinical pathology 1995;43(4):337-41.
1995: Ryozo Nagai; K Miyazawa
[Molecular biology in cardiovascular medicine].
Rinsho byori. The Japanese journal of clinical pathology 1995;43(4):335-6.
1995: M Aikawa; H S Kim; Makoto Kuro-o; Ichiro Manabe; M Watanabe; H Yamaguchi; Y Yazaki; Ryozo Nagai
Phenotypic modulation of smooth muscle cells during progression of human atherosclerosis as determined by altered expression of myosin heavy chain isoforms.
Annals of the New York Academy of Sciences 1995;748():578-85.
1995: M Aikawa; H Yamaguchi; Y Yazaki; Ryozo Nagai
Smooth muscle phenotypes in developing and atherosclerotic human arteries demonstrated by myosin expression.
Journal of atherosclerosis and thrombosis 1995;2(1):14-23.
1995: Makoto Kuro-o; K Hanaoka; Yukio Hiroi; T Noguchi; Y Fujimori; S Takewaki; M Hayasaka; H Katoh; A Miyagishi; Ryozo Nagai
Salt-sensitive hypertension in transgenic mice overexpressing Na(+)-proton exchanger.
Circulation research 1995;76(1):148-53.
1994: T Morita; Hiroki Kurihara; Koji Maemura; Masao Yoshizumi; Ryozo Nagai; Y Yazaki
Role of Ca2+ and protein kinase C in shear stress-induced actin depolymerization and endothelin 1 gene expression.
Circulation research 1994;75(4):630-6.
1994: Koji Maemura; Hiroki Kurihara; Yukiko Kurihara; Ryozo Nagai; Y Yazaki
Isolation and characterization of vascular endothelial cells derived from mice lacking endothelin-1.
Biochemical and biophysical research communications 1994;201(2):538-45.
1994: Yukiko Kurihara; Hiroki Kurihara; H Suzuki; T Kodama; Koji Maemura; Ryozo Nagai; Hiromi Oda; Tomoyuki Kuwaki; WH Cao; N Kamada
Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1.
Nature 1994;368(6473):703-10.
1994: T Suzuki; Ryozo Nagai; T Yamazaki; Ichiro Shiojima; Koji Maemura; K Yamaoki; N Tanaka; T Machida; Yutaka Kotsuka; Akira Furuse
Rapid growth of intracranial aneurysms secondary to cardiac myxoma.
Neurology 1994;44(3 Pt 1):570-1.
1994: T Suzuki; Ryozo Nagai; Hiroki Kurihara; Yukiko Kurihara; Tadashi Yamazaki; E Ho; Koji Maemura; Ichiro Shiojima; K Yamaoki; Akira Furuse
Stenotic bicuspid aortic valve associated with a ventricular septal defect in an adult presenting with congestive heart failure: a rare observation.
European heart journal 1994;15(3):402-3.
1994: S Takewaki; K Okuzumi; Ichiro Manabe; M Tanimura; K Miyamura; K Nakahara; Y Yazaki; A Ohkubo; Ryozo Nagai
Nucleotide sequence comparison of the mycobacterial dnaJ gene and PCR-restriction fragment length polymorphism analysis for identification of mycobacterial species.
International journal of systematic bacteriology 1994;44(1):159-66.
1993: T Morita; Masao Yoshizumi; Hiroki Kurihara; Koji Maemura; Ryozo Nagai; Y Yazaki
Shear stress increases heparin-binding epidermal growth factor-like growth factor mRNA levels in human vascular endothelial cells.
Biochemical and biophysical research communications 1993;197(1):256-62.
1993: H S Kim; M Aikawa; K Kimura; Makoto Kuro-o; K Nakahara; T Suzuki; H Katoh; E Okamoto; Y Yazaki; Ryozo Nagai
Ductus arteriosus. Advanced differentiation of smooth muscle cells demonstrated by myosin heavy chain isoform expression in rabbits.
Circulation 1993;88(4 Pt 1):1804-10.
1993: Tadashi Yamazaki; Kazuyuki Tobe; E Hoh; Koji Maemura; T Kaida; Issei Komuro; H Tamemoto; Takashi Kadowaki; Ryozo Nagai; Y Yazaki
Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes.
The Journal of biological chemistry 1993;268(16):12069-76.
1993: Makoto Kuro-o; Ryozo Nagai; Y Yazaki; K Hanaoka; Y Nabeshima
[Production of transgenic mice overexpressing rabbit Na+/H+ antiporter].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(6):1524-9.
1993: S Takewaki; Ryozo Nagai
[Activation of Na(+)-H+ antiporter gene expression during vascular smooth muscle proliferation and cardiac hypertrophy].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(6):1518-23.
1993: Ryozo Nagai
[Molecular basis for heart failure].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(5):1217-21.
1993: M Isobe; K Yamaoki; T Sugiyama; Yoshinori Seko; Masao Yoshizumi; Ryozo Nagai; Y Yazaki
Right ventricular inflow obstruction due to giant hematoma formed by chronic constrictive pericarditis.
Internal medicine (Tokyo, Japan) 1993;32(4):346-9.
1993: Ryozo Nagai; T Yamazaki; Ichiro Shiojima; Y Yazaki
[Molecular basis for cardiac functions].
Rinsho byori. The Japanese journal of clinical pathology 1993;41(4):409-14.
1993: Y Yazaki; Issei Komuro; Tadashi Yamazaki; Kazuyuki Tobe; Koji Maemura; Takashi Kadowaki; Ryozo Nagai
Role of protein kinase system in the signal transduction of stretch-mediated protooncogene expression and hypertrophy of cardiac myocytes.
Molecular and cellular biochemistry 1993;119(1-2):11-6.
1993: S Takewaki; K Okuzumi; H Ishiko; K Nakahara; A Ohkubo; Ryozo Nagai
Genus-specific polymerase chain reaction for the mycobacterial dnaJ gene and species-specific oligonucleotide probes.
Journal of clinical microbiology 1993;31(2):446-50.
1993: T Morita; Hiroki Kurihara; Masao Yoshizumi; Koji Maemura; Takao Sugiyama; Ryozo Nagai; Y Yazaki
Human polymorphonuclear leukocytes have dual effects on endothelin-1: the induction of endothelin-1 mRNA expression in vascular endothelial cells and modification of the endothelin-1 molecule.
Heart and vessels 1993;8(1):1-6.
1993: T Yamazaki; Yoshinori Seko; Ryozo Nagai; Y Yazaki
[Roles of cell-adhesion molecules in myocardial reperfusion injury].
Japanese circulation journal 1993;57 Suppl 4():1344-6.
1992: K Nakahara; H Nishimura; Makoto Kuro-o; S Takewaki; M Iwase; A Ohkubo; Y Yazaki; Ryozo Nagai
Identification of three types of PDGF-A chain gene transcripts in rabbit vascular smooth muscle and their regulated expression during development and by angiotensin II.
Biochemical and biophysical research communications 1992;184(2):811-8.
1992: Ichiro Shiojima; Issei Komuro; K Ieki; Ryozo Nagai; Y Yazaki
[Molecular mechanism of diastolic dysfunction in pressure overload cardiac hypertrophy].
Japanese circulation journal 1992;56 Suppl 5():1268-72.
1991: Ryozo Nagai; Y Yazaki
[Biochemical diagnosis for acute myocardial infarction; myosin light chain].
Rinsho byori. The Japanese journal of clinical pathology 1991;39(11):1161-5.
1991: Makoto Kuro-o; Ryozo Nagai; K Nakahara; H Katoh; R C Tsai; H Tsuchimochi; Y Yazaki; A Ohkubo; F Takaku
cDNA cloning of a myosin heavy chain isoform in embryonic smooth muscle and its expression during vascular development and in arteriosclerosis.
The Journal of biological chemistry 1991;266(6):3768-73.
1990: Ryozo Nagai; S Takewaki; A Wada; K Okuzumi; A Tobita; A Ohkubo
[Rapid detection and identification of mycobacterial DNA by PCR].
Rinsho byori. The Japanese journal of clinical pathology 1990;38(11):1247-53.
1990: M Isobe; Ryozo Nagai; F Takaku; T Yamaguchi; Y Yazaki
[Reduction of myocardial infarct size by early intracoronary thrombolysis as assessed by serum cardiac myosin light chains and left ventricular function].
Journal of cardiology 1990;20(3):521-30.
1989: Makoto Kuro-o; Ryozo Nagai; H Tsuchimochi; H Katoh; Y Yazaki; A Ohkubo; F Takaku
Developmentally regulated expression of vascular smooth muscle myosin heavy chain isoforms.
The Journal of biological chemistry 1989;264(31):18272-5.
1989: M Isobe; Ryozo Nagai; K Yamaoki; H Nakaoka; F Takaku; Y Yazaki
Quantification of myocardial infarct size after coronary reperfusion by serum cardiac myosin light chain II in conscious dogs.
Circulation research 1989;65(3):684-94.
1989: M Isobe; Ryozo Nagai; F Takaku; Y Yazaki
Infarct sizing after reperfusion by two-dimensional echocardiography and serum cardiac myosin light chain II in conscious dogs: dissociation between early left ventricular wall motion and ultimate infarct size.
Japanese circulation journal 1989;53(9):1100-7.
1989: Hiroki Kurihara; K Yamaoki; Ryozo Nagai; Masao Yoshizumi; F Takaku; H Satoh; J Inui; Y Yazaki
Endothelin: a potent vasoconstrictor associated with coronary vasospasm.
Life sciences 1989;44(25):1937-43.
1989: Hiroki Kurihara; Masao Yoshizumi; Takao Sugiyama; K Yamaoki; Ryozo Nagai; F Takaku; H Satoh; J Inui; M Yanagisawa; T Masaki
The possible role of endothelin-1 in the pathogenesis of coronary vasospasm.
Journal of cardiovascular pharmacology 1989;13 Suppl 5():S132-7; discussion S142.
1987: M Isobe; Ryozo Nagai; S Ueda; H Tsuchimochi; H Nakaoka; F Takaku; T Yamaguchi; K Machii; M Nobuyoshi; Y Yazaki
Quantitative relationship between left ventricular function and serum cardiac myosin light chain I levels after coronary reperfusion in patients with acute myocardial infarction.
Circulation 1987;76(6):1251-61.