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Akira Naganuma

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Gi-Wook Hwang; Jin-Yong Lee; Fujio Mastuyama; Tsutomu Takahashi; Akira Naganuma
Deletion of the ubiquitin-conjugating enzyme Ubc2 confers resistance to methylmercury in budding yeast by promoting Whi2 degradation.
Naoko Kubota; Takashi Fukuda; Yasuhiro Furuichi; Yasutaka Inayoshi; Kenta Iwai; Kazuhiro Kataoka; Michinori Kohara; Akira Naganuma; Akio Nomoto; Naoko Satoh; Akira Shimamoto; Hiroshi Tomoda; Shusuke Kuge
HSC90 is required for nascent hepatitis C virus core protein stability in yeast cells.
Gi-Wook Hwang; Yukiyoshi Kimura; Jin-Yong Lee; Tsutomu Takahashi; Akira Naganuma
Identification of deubiquitinating enzymes involved in methylmercury toxicity in Saccharomyces cerevisiae.

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2013: Gi-Wook Hwang; Jin-Yong Lee; Fujio Mastuyama; Tsutomu Takahashi; Akira Naganuma
Deletion of the ubiquitin-conjugating enzyme Ubc2 confers resistance to methylmercury in budding yeast by promoting Whi2 degradation.
The Journal of toxicological sciences 2013;38(2):301-3.
2012: Naoko Kubota; Takashi Fukuda; Yasuhiro Furuichi; Yasutaka Inayoshi; Kenta Iwai; Kazuhiro Kataoka; Michinori Kohara; Akira Naganuma; Akio Nomoto; Naoko Satoh; Akira Shimamoto; Hiroshi Tomoda; Shusuke Kuge
HSC90 is required for nascent hepatitis C virus core protein stability in yeast cells.
FEBS letters 2012;586(16):2318-25.
2012: Gi-Wook Hwang; Yukiyoshi Kimura; Jin-Yong Lee; Tsutomu Takahashi; Akira Naganuma
Identification of deubiquitinating enzymes involved in methylmercury toxicity in Saccharomyces cerevisiae.
The Journal of toxicological sciences 2012;37(6):1287-90.
2012: Gi-Wook Hwang; Yousuke Ogiwara; Tsutomu Takahashi; Akira Naganuma
Ubiquitin-conjugating enzyme Cdc34 mediates methylmercury resistance in Saccharomyces cerevisiae by increasing Whi2 degradation.
The Journal of toxicological sciences 2012;37(6):1283-6.
2012: Jin-Yong Lee; Gi-Wook Hwang; Min-Seok Kim; Tsutomu Takahashi; Akira Naganuma
Methylmercury induces a brain-specific increase in chemokine CCL4 expression in mice.
The Journal of toxicological sciences 2012;37(6):1279-82.
2012: Min-Seok Kim; Jin-Yong Lee; Gi-Wook Hwang; Tsutomu Takahashi; Akira Naganuma
Methylmercury induces CCL2 expression through activation of NF-κB in human 1321N1 astrocytes.
The Journal of toxicological sciences 2012;37(6):1275-8.
2012: Aya Yokomakura; Seong-Eun Oh; Kazuo Ohuchi; Tsutomu Takahashi; JangJa Hong; Gi-Wook Hwang; Jin-Yong Lee; Nariyasu Mano; Akira Naganuma
Increased production of reactive oxygen species by the vacuolar-type (H(+))-ATPase inhibitors bafilomycin A1 and concanamycin A in RAW 264 cells.
The Journal of toxicological sciences 2012;37(5):1045-8.
2011: Daisuke Saigusa; Masatoshi Shibuya; Yoshihisa Tomioka; Hiroyuki Yamakoshi; Yoshiharu Iwabuchi; Daisuke Jinno; Yoshihiro Mimaki; Akira Naganuma; Yasushi Ohizumi; Akihito Yokosuka; Tohru Yamakuni
High-performance liquid chromatography with photodiode array detection for determination of nobiletin content in the brain and serum of mice administrated the natural compound.
Analytical and bioanalytical chemistry 2011;400(10):3635-41.
2011: Gi-Wook Hwang; Jin-Yong Lee; Katsunori Ryoke; Fujio Matsuyama; Jong-Mu Kim; Tsutomu Takahashi; Akira Naganuma
Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercury.
The Journal of toxicological sciences 2011;36(3):389-91.
2011: Tsutomu Takahashi; Shohei Satake; Ken-ichiro Hirose; Gi-Wook Hwang; Akira Naganuma
A screening for essential cell growth-related genes involved in arsenite toxicity in Saccharomyces cerevisiae.
The Journal of toxicological sciences 2011;36(6):859-61.
2011: Tsutomu Takahashi; Shigehiro Yoneda; Gi-Wook Hwang; Takuro Masuda; Shingo Nakashima; Akira Naganuma
Overexpression of CLN1, CLN2, or ERG13 increases resistance to adriamycin in Saccharomyces cerevisiae.
The Journal of toxicological sciences 2011;36(6):855-7.
2011: Gi-Wook Hwang; Jin-Yong Lee; Katsunori Ryoke; Tsutomu Takahashi; Akira Naganuma
siRNA-mediated silencing of the gene for heat shock transcription factor 1 causes hypersensitivity to methylmercury in HEK293 cells.
The Journal of toxicological sciences 2011;36(6):851-3.
2011: Gi-Wook Hwang; Ke Du; Tsutomu Takahashi; Akira Naganuma
Inhibition of F-box protein FBXO6 gene expression by RNA interference enhances cadmium toxicity in HEK293 cells.
The Journal of toxicological sciences 2011;36(6):847-9.
2011: Yoshihisa Tomioka; Noriyasu Hirasawa; Akira Naganuma
[Education for six-years graduate school of pharmaceutical sciences: a case of Tohoku University].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2011;131(6):933-8.
2010: Gi-Wook Hwang; Seong-Eun Oh; Tsutomu Takahashi; Jin-Yong Lee; Akira Naganuma
siRNA-mediated knockdown of the melanocortin 2 receptor accessory protein 2 (MRAP2) gene confers resistance to methylmercury on HEK293 cells.
The Journal of toxicological sciences 2010;35(6):947-50.
2010: Tsutomu Takahashi; Toomi Yano; Junxuan Zhu; Gi-Wook Hwang; Akira Naganuma
Overexpression of FAP7, MIG3, TMA19, or YLR392c confers resistance to arsenite on Saccharomyces cerevisiae.
The Journal of toxicological sciences 2010;35(6):945-6.
2010: Gi-Wook Hwang; Katsunori Ryoke; Tsutomu Takahashi; Akira Naganuma
Silencing of the gene for homeobox protein HOXB13 by siRNA confers resistance to methylmercury on HEK293 cells.
The Journal of toxicological sciences 2010;35(6):941-4.
2010: Gi-Wook Hwang; Mayumi Tobita; Tsutomu Takahashi; Shusuke Kuge; Kayoko Kita; Akira Naganuma
siRNA-mediated AMPKalpha1 subunit gene PRKAA1 silencing enhances methylmercury toxicity in HEK293 cells.
The Journal of toxicological sciences 2010;35(4):601-4.
2009: Jin-Yong Lee; Gi-Wook Hwang; Akira Naganuma
Rip1 enhances methylmercury toxicity through production of reactive oxygen species (ROS) in budding yeast.
The Journal of toxicological sciences 2009;34(6):715-7.
2009: Tsutomu Takahashi; Ken-ichiro Hirose; Emi Mizutani; Akira Naganuma
Dysfunctional nascent polypeptide-associated complex (NAC) activity in ribosomes enhances adriamycin toxicity in budding yeast.
The Journal of toxicological sciences 2009;34(6):703-8.
2009: Gi-Wook Hwang; Kanae Sasaki; Tsutomu Takahashi; Reiko Yamamoto; Akira Naganuma
Overexpression of Ycg1 or Ydr520c confers resistance to cadmium in Saccharomyces cerevisiae.
The Journal of toxicological sciences 2009;34(4):441-3.
2009: Gi-Wook Hwang; Naomi Wada; Shusuke Kuge; Akira Naganuma
Overexpression of the novel F-box protein Ymr258c confers resistance to methylmercury in Saccharomyces cerevisiae.
The Journal of toxicological sciences 2009;34(4):413-6.
2009: Tsuyoshi Tachibana; Shoko Okazaki; Asako Murayama; Akira Naganuma; Akio Nomoto; Shusuke Kuge
A major peroxiredoxin-induced activation of Yap1 transcription factor is mediated by reduction-sensitive disulfide bonds and reveals a low level of transcriptional activation.
The Journal of biological chemistry 2009;284(7):4464-72.
2008: Kiyoshi Shibuya; Noriko Nishimura; Junko S Suzuki; Chiharu Tohyama; Akira Naganuma; Masahiko Satoh
Role of metallothionein as a protective factor against radiation carcinogenesis.
The Journal of toxicological sciences 2008;33(5):651-5.
2008: Kiyoshi Shibuya; Junko S Suzuki; Hideaki Kito; Akira Naganuma; Chiharu Tohyama; Masahiko Satoh
Protective role of metallothionein in bone marrow injury caused by X-irradiation.
The Journal of toxicological sciences 2008;33(4):479-84.
2008: Gi-Wook Hwang; Takemitsu Furuchi; Akira Naganuma
The ubiquitin-conjugating enzymes, Ubc4 and Cdc34, mediate cadmium resistance in budding yeast through different mechanisms.
Life sciences 2008;82(23-24):1182-5.
2007: Gi-Wook Hwang; Tatsuya Hayashi; Kayoko Kita; Tsutomu Takahashi; Shusuke Kuge; Akira Naganuma
siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells.
The Journal of toxicological sciences 2007;32(5):581-3.
2007: Gi-Wook Hwang; Takemitsu Furuchi; Akira Naganuma
Ubiquitin-conjugating enzyme Cdc34 mediates cadmium resistance in budding yeast through ubiquitination of the transcription factor Met4.
Biochemical and biophysical research communications 2007;363(3):873-8.
2007: Shoko Okazaki; Tsuyoshi Tachibana; Akira Naganuma; Nariyasu Mano; Shusuke Kuge
Multistep disulfide bond formation in Yap1 is required for sensing and transduction of H2O2 stress signal.
Molecular cell 2007;27(4):675-88.
2007: Naoko Kubota; Akira Naganuma; Shusuke Kuge
DNA microarray analysis of transcriptional responses of yeast cells to expression of core protein of hepatitis C virus.
The Journal of toxicological sciences 2007;32(2):201-4.
2007: Akiko Kimura; Kazuaki Ohashi; Akira Naganuma
Cisplatin upregulates Saccharomyces cerevisiae genes involved in iron homeostasis through activation of the iron insufficiency-responsive transcription factor Aft1.
Journal of cellular physiology 2007;210(2):378-84.
2006: Gi-Wook Hwang; Yosuke Ishida; Akira Naganuma
Identification of F-box proteins that are involved in resistance to methylmercury in Saccharomyces cerevisiae.
FEBS letters 2006;580(30):6813-8.
2006: Tsutomu Takahashi; Takemitsu Furuchi; Akira Naganuma
Endocytic Ark/Prk kinases play a critical role in adriamycin resistance in both yeast and mammalian cells.
Cancer research 2006;66(24):11932-7.
2006: Gi-Wook Hwang; Akira Naganuma
DNA microarray analysis of transcriptional responses of human neuroblastoma IMR-32 cells to methylmercury.
The Journal of toxicological sciences 2006;31(5):537-8.
2006: Kayoko Kita; Nobuhiko Miura; Minoru Yoshida; Kentaro Yamazaki; Takayoshi Ohkubo; Yutaka Imai; Akira Naganuma
Potential effect on cellular response to cadmium of a single-nucleotide A --> G polymorphism in the promoter of the human gene for metallothionein IIA.
Human genetics 2006;120(4):553-60.
2006: Akiko Kimura; Kazuaki Ohashi; Reiko Yamamoto; Akira Naganuma
Cisplatin-induced expression of iron-retaining genes FIT2 and FIT3 in Saccharomyces cerevisiae.
The Journal of toxicological sciences 2006;31(3):287-90.
2005: Gi-Wook Hwang; Daisuke Sasaki; Akira Naganuma
Overexpression of Rad23 confers resistance to methylmercury in saccharomyces cerevisiae via inhibition of the degradation of ubiquitinated proteins.
Molecular pharmacology 2005;68(4):1074-8.
2005: Gi-Wook Hwang; Yuko Furuoya; Ayano Hiroshima; Takemitsu Furuchi; Akira Naganuma
Overexpression of Bop3 confers resistance to methylmercury in Saccharomyces cerevisiae through interaction with other proteins such as Fkh1, Rts1, and Msn2.
Biochemical and biophysical research communications 2005;330(2):378-85.
2005: Shoko Okazaki; Akira Naganuma; Shusuke Kuge
Peroxiredoxin-mediated redox regulation of the nuclear localization of Yap1, a transcription factor in budding yeast.
Antioxidants & redox signaling 2005;7(3-4):327-34.
2005: Tsutomu Takahashi; Takemitsu Furuchi; Akira Naganuma
A novel role for Bsd2 in the resistance of yeast to adriamycin.
Journal of cellular physiology 2005;202(1):100-4.
2004: Takemitsu Furuchi; Katsushi Nitta; Tsutomu Takahashi; Akira Naganuma
Overexpression of Ssl2p confers resistance to adriamycin and actinomycin D in Saccharomyces cerevisiae.
Biochemical and biophysical research communications 2004;314(3):844-8.
2004: Takemitsu Furuchi; Tsutomu Takahashi; Shogo Tanaka; Katsushi Nitta; Akira Naganuma
Functions of yeast helicase Ssl2p that are essential for viability are also involved in protection from the toxicity of adriamycin.
Nucleic acids research 2004;32(8):2578-85.
2004: Yukihiro Kondo; Seiichiro Himeno; Masahiko Satoh; Akira Naganuma; Taiji Nishimura; Nobumasa Imura
Citrate enhances the protective effect of orally administered bismuth subnitrate against the nephrotoxicity of cis-diamminedichloroplatinum.
Cancer chemotherapy and pharmacology 2004;53(1):33-8.
2003: Kazuaki Ohashi; Kazuki Kajiya; Sachiko Inaba; Tatsuya Hasegawa; Yoshiyuki Seko; Takemitsu Furuchi; Akira Naganuma
Copper(II) protects yeast against the toxicity of cisplatin independently of the induction of metallothionein and the inhibition of platinum uptake.
Biochemical and biophysical research communications 2003;310(1):148-52.
2002: Gi-Wook Hwang; Takemitsu Furuchi; Akira Naganuma
A ubiquitin-proteasome system is responsible for the protection of yeast and human cells against methylmercury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):709-11.
2002: Takemitsu Furuchi; Gi-Wook Hwang; Akira Naganuma
Overexpression of the ubiquitin-conjugating enzyme Cdc34 confers resistance to methylmercury in Saccharomyces cerevisiae.
Molecular pharmacology 2002;61(4):738-41.
2002: Akira Naganuma; Takemitsu Furuchi; Nobuhiko Miura; Gi-Wook Hwang; Shusuke Kuge
Investigation of intracellular factors involved in methylmercury toxicity.
The Tohoku journal of experimental medicine 2002;196(2):65-70.
2002: Shinichi Miyairi; Akira Naganuma
Metallothionein determination by isocratic HPLC with fluorescence derivatization.
Methods in molecular biology (Clifton, N.J.) 2002;186():273-83.
2001: K Ikeda; K Miura; Seiichiro Himeno; Nobumasa Imura; Akira Naganuma
Glutathione content is correlated with the sensitivity of lines of PC12 cells to cisplatin without a corresponding change in the accumulation of platinum.
Molecular and cellular biochemistry 2001;219(1-2):51-6.
2001: Takemitsu Furuchi; H Ishikawa; Nobuhiko Miura; M Ishizuka; K Kajiya; Shusuke Kuge; Akira Naganuma
Two nuclear proteins, Cin5 and Ydr259c, confer resistance to cisplatin in Saccharomyces cerevisiae.
Molecular pharmacology 2001;59(3):470-4.
2000: Nobuhiko Miura; Akira Naganuma
Metallothionein mediates gene expression of 3.1 mRNA (PTZ17) related to epileptic seizure.
FEBS letters 2000;479(3):146-8.
2000: Masahiko Satoh; Akira Naganuma; Nobumasa Imura
Modulation of adriamycin toxicity by tissue-specific induction of metallothionein synthesis in mice.
Life sciences 2000;67(6):627-34.
2000: Akira Naganuma; Nobuhiko Miura; S Kaneko; T Mishina; S Hosoya; Shinichi Miyairi; Takemitsu Furuchi; Shusuke Kuge
GFAT as a target molecule of methylmercury toxicity in Saccharomyces cerevisiae.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(7):968-72.
2000: H Toyoda; T Mizushima; M Satoh; N Iizuka; A Nomoto; H Chiba; Masaharu Mita; Akira Naganuma; Seiichiro Himeno; Nobumasa Imura
HeLa cell transformants overproducing mouse metallothionein show in vivo resistance to cis-platinum in nude mice.
Japanese journal of cancer research : Gann 2000;91(1):91-8.
1999: Nobuhiko Miura; Y Matsumoto; Shinichi Miyairi; S Nishiyama; Akira Naganuma
Protective effects of triterpene compounds against the cytotoxicity of cadmium in HepG2 cells.
Molecular pharmacology 1999;56(6):1324-8.
1999: Nobuhiko Miura; S Kaneko; S Hosoya; Takemitsu Furuchi; K Miura; Shusuke Kuge; Akira Naganuma
Overexpression of L-glutamine:D-fructose-6-phosphate amidotransferase provides resistance to methylmercury in Saccharomyces cerevisiae.
FEBS letters 1999;458(2):215-8.
1999: T Yasuno; T Matsumura; T Shikata; J Inazawa; T Sakabe; S Tsuchida; T Takahata; Shinichi Miyairi; Akira Naganuma; Tadashi Sawada
Establishment and characterization of a cisplatin-resistant human neuroblastoma cell line.
Anticancer research 1999;19(5B):4049-57.
1999: I Asahi; N Miura; Yukako Yamabe; H Toyoda; Nobumasa Imura; M Koyama; Akira Naganuma
PF1070A, a novel and potent inducer of the synthesis of metallothionein.
Biochemistry 1999;38(32):10415-23.
1999: Shinichi Miyairi; K Maeda; T Oe; T Kato; Akira Naganuma
Effect of metal ions on the stable adduct formation of 16alpha-hydroxyestrone with a primary amine via the Heyns rearrangement.
Steroids 1999;64(4):252-8.
1999: Toshiko Tanaka-Kagawa; J Kitahara; Y Seko; H Toyoda; Nobumasa Imura; Akira Naganuma
Reduced sensitivity of HeLa cells to cis-platinum by simultaneous overexpression of copper, zinc-superoxide dismutase and catalase.
Biochemical pharmacology 1999;57(5):545-8.
1998: N Miura; M Satoh; Nobumasa Imura; Akira Naganuma
Protective effect of bismuth nitrate against injury to the bone marrow by gamma-irradiation in mice: possible involvement of induction of metallothionein synthesis.
The Journal of pharmacology and experimental therapeutics 1998;286(3):1427-30.
1998: I Nakagawa; M Suzuki; Nobumasa Imura; Akira Naganuma
Involvement of oxidative stress in paraquat-induced metallothionein synthesis under glutathione depletion.
Free radical biology & medicine 1998;24(9):1390-5.
1998: Shinichi Miyairi; S Shibata; Akira Naganuma
Determination of metallothionein by high-performance liquid chromatography with fluorescence detection using an isocratic solvent system.
Analytical biochemistry 1998;258(2):168-75.
1998: Y Okazaki; N Miura; M Satoh; Nobumasa Imura; Akira Naganuma
Metallothionein-mediated resistance to multiple drugs can be induced by several anticancer drugs in mice.
Biochemical and biophysical research communications 1998;245(3):815-8.
1998: T Oe; T Ohyagi; Akira Naganuma
Determination of gamma-glutamylglutathione and other low-molecular-mass biological thiol compounds by isocratic high-performance liquid chromatography with fluorimetric detection.
Journal of chromatography. B, Biomedical sciences and applications 1998;708(1-2):285-9.
1998: Toshiko Tanaka-Kagawa; M Suzuki; Akira Naganuma; N Yamanaka; Nobumasa Imura
Strain difference in sensitivity of mice to renal toxicity of inorganic mercury.
The Journal of pharmacology and experimental therapeutics 1998;285(1):335-41.
1998: Akira Naganuma; K Miura; Toshiko Tanaka-Kagawa; J Kitahara; Y Seko; H Toyoda; Nobumasa Imura
Overexpression of manganese-superoxide dismutase prevents methylmercury toxicity in HeLa cells.
Life sciences 1998;62(12):PL157-61.
1997: T Urano; Nobumasa Imura; Akira Naganuma
Inhibitory effect of selenium on biliary secretion of methyl mercury in rats.
Biochemical and biophysical research communications 1997;239(3):862-7.
1997: Akira Naganuma
[Metallothionein].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(5):1091-5.
1995: I Nakagawa; M Suzuki; Takahiro Yanagiya; Nobumasa Imura; Akira Naganuma
Effect of glutathione depletion on metallothionein synthesis induced by paraquat in mice.
The Tohoku journal of experimental medicine 1995;177(3):249-62.
1995: I Nakagawa; M Suzuki; Nobumasa Imura; Akira Naganuma
Enhancement of paraquat toxicity by glutathione depletion in mice in vivo and in vitro.
The Journal of toxicological sciences 1995;20(5):557-64.
1995: I Nakagawa; E Nishi; Akira Naganuma; Nobumasa Imura
Effect of preinduction of metallothionein synthesis on clastogenicity of anticancer drugs in mice.
Mutation research 1995;348(1):37-43.
1993: M Satoh; D M Kloth; S A Kadhim; Joseph L Chin; Akira Naganuma; Nobumasa Imura; M George Cherian
Modulation of both cisplatin nephrotoxicity and drug resistance in murine bladder tumor by controlling metallothionein synthesis.
Cancer research 1993;53(8):1829-32.
1993: Toshiko Tanaka-Kagawa; Akira Naganuma; Nobumasa Imura
Tubular secretion and reabsorption of mercury compounds in mouse kidney.
The Journal of pharmacology and experimental therapeutics 1993;264(2):776-82.
1992: T Tanaka; Akira Naganuma; Nobumasa Imura
Routes for renal transport of methylmercury in mice.
European journal of pharmacology 1992;228(1):9-14.
1992: M Satoh; Akira Naganuma; Nobumasa Imura
Effect of preinduction of metallothionein on paraquat toxicity in mice.
Archives of toxicology 1992;66(2):145-8.
1992: M Satoh; Akira Naganuma; Nobumasa Imura
Effect of coadministration of selenite on the toxicity and antitumor activity of cis-diamminedichloroplatinum (II) given repeatedly to mice.
Cancer chemotherapy and pharmacology 1992;30(6):439-43.
1991: T Tanaka; Akira Naganuma; K Kobayashi; Nobumasa Imura
An explanation for strain and sex differences in renal uptake of methylmercury in mice.
Toxicology 1991;69(3):317-29.
1990: T Tanaka; Akira Naganuma; Nobumasa Imura
Role of gamma-glutamyltranspeptidase in renal uptake and toxicity of inorganic mercury in mice.
Toxicology 1990;60(3):187-98.
1990: T Urano; A Iwasaki; S Himeno; Akira Naganuma; Nobumasa Imura
Absorption of methylmercury compounds from rat intestine.
Toxicology letters 1990;50(2-3):159-64.
1989: M Satoh; N Miura; Akira Naganuma; N Matsuzaki; E Kawamura; Nobumasa Imura
Prevention of adverse effects of gamma-ray irradiation after metallothionein induction by bismuth subnitrate in mice.
European journal of cancer & clinical oncology 1989;25(12):1727-31.
1989: M Satoh; Akira Naganuma; Nobumasa Imura
Optimum schedule of selenium administration to reduce lethal and renal toxicities of cis-diamminedichloroplatinum in mice.
Journal of pharmacobio-dynamics 1989;12(4):246-53.
1988: M Satoh; Akira Naganuma; Nobumasa Imura
Involvement of cardiac metallothionein in prevention of adriamycin induced lipid peroxidation in the heart.
Toxicology 1988;53(2-3):231-7.
1988: T Urano; Akira Naganuma; Nobumasa Imura
Species differences in biliary excretion of methylmercury--role of non-protein sulfhydryls in bile.
Research communications in chemical pathology and pharmacology 1988;62(2):339-51.
1988: T Urano; Akira Naganuma; Nobumasa Imura
Methylmercury-cysteinylglycine constitutes the main form of methylmercury in rat bile.
Research communications in chemical pathology and pharmacology 1988;60(2):197-210.
1988: N Nishikido; Y Satoh; I Iwai; M Ishii; Akira Naganuma; Nobumasa Imura
Specific alteration of the form of selenium in fetal liver on maternal methylmercury treatment.
Toxicology and applied pharmacology 1988;92(3):497-9.
1988: Akira Naganuma; M Satoh; Nobumasa Imura
Specific reduction of toxic side effects of adriamycin by induction of metallothionein in mice.
Japanese journal of cancer research : Gann 1988;79(3):406-11.
1988: N Nishikido; Y Satoh; Akira Naganuma; Nobumasa Imura
Effect of maternal selenium deficiency on the teratogenicity of methylmercury.
Toxicology letters 1988;40(2):153-7.
1988: Akira Naganuma; N Oda-Urano; T Tanaka; Nobumasa Imura
Possible role of hepatic glutathione in transport of methylmercury into mouse kidney.
Biochemical pharmacology 1988;37(2):291-6.
1988: M Satoh; Akira Naganuma; Nobumasa Imura
Metallothionein induction prevents toxic side effects of cisplatin and adriamycin used in combination.
Cancer chemotherapy and pharmacology 1988;21(2):176-8.
1987: N Nishikido; K Furuyashiki; Akira Naganuma; T Suzuki; Nobumasa Imura
Maternal selenium deficiency enhances the fetolethal toxicity of methyl mercury.
Toxicology and applied pharmacology 1987;88(3):322-8.
1987: Nobumasa Imura; Akira Naganuma; M Satoh; Y Koyama
Induction of renal metallothionein allows increasing dose of an extensively used antitumor drug, cis-diamminedichloroplatinum.
Experientia. Supplementum 1987;52():655-60.