FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Taku Nagao

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Myocardium

Concepts & Ideas

Disorders

Blood Pressure

Co-author Network

Publications

TOP 3
Motohiro Nishida; Yoji Sato; Aya Uemura; Yusuke Narita; Hidetoshi Tozaki-Saitoh; Michio Nakaya; Tomomi Ide; Kazuhiro Suzuki; Kazuhide Inoue; Taku Nagao; Hitoshi Kurose
P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis.
Naoya Onohara; Motohiro Nishida; Ryuji Inoue; Hiroyuki Kobayashi; Hideki Sumimoto; Yoji Sato; Yasuo Mori; Taku Nagao; Hitoshi Kurose
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.
Hidetoshi Tozaki-Saitoh; Schuichi Koizumi; Yoji Sato; Makoto Tsuda; Taku Nagao; Kazuhide Inoue
Retinoic acids increase P2X2 receptor expression through the 5'-flanking region of P2rx2 gene in rat phaeochromocytoma PC-12 cells.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Taku Nagao (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2008: Motohiro Nishida; Yoji Sato; Aya Uemura; Yusuke Narita; Hidetoshi Tozaki-Saitoh; Michio Nakaya; Tomomi Ide; Kazuhiro Suzuki; Kazuhide Inoue; Taku Nagao; Hitoshi Kurose
P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis.
The EMBO journal 2008;27(23):3104-15.
2006: Naoya Onohara; Motohiro Nishida; Ryuji Inoue; Hiroyuki Kobayashi; Hideki Sumimoto; Yoji Sato; Yasuo Mori; Taku Nagao; Hitoshi Kurose
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.
The EMBO journal 2006;25(22):5305-16.
2006: Hidetoshi Tozaki-Saitoh; Schuichi Koizumi; Yoji Sato; Makoto Tsuda; Taku Nagao; Kazuhide Inoue
Retinoic acids increase P2X2 receptor expression through the 5'-flanking region of P2rx2 gene in rat phaeochromocytoma PC-12 cells.
Molecular pharmacology 2006;70(1):319-28.
2005: Tomomi Fujii; Naoya Onohara; Yoshiko Maruyama; Shihori Tanabe; Hiroyuki Kobayashi; Masashi Fukutomi; Yuichi Nagamatsu; Naoki Nishihara; Ryuji Inoue; Hideki Sumimoto; Futoshi Shibasaki; Taku Nagao; Motohiro Nishida; Hitoshi Kurose
Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts.
The Journal of biological chemistry 2005;280(24):23041-7.
2005: Motohiro Nishida; Shihori Tanabe; Yoshiko Maruyama; Supachoke Mangmool; Kyoji Urayama; Yuichi Nagamatsu; Shuichi Takagahara; Justin H Turner; Tohru Kozasa; Hiroyuki Kobayashi; Yoji Sato; Toru Kawanishi; Ryuji Inoue; Taku Nagao; Hitoshi Kurose
G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes.
The Journal of biological chemistry 2005;280(18):18434-41.
2003: Keiichiro Tashiro; Taku Nagao; Hitoshi Kurose; Hidenori Ichijo; Tetsuro Urushidani
Role of Rho in rabbit parietal cell.
Journal of cellular physiology 2003;197(3):409-17.
2003: Hajime Takamatsu; Taku Nagao; Hidenori Ichijo; Satomi Adachi-Akahane
L-type Ca2+ channels serve as a sensor of the SR Ca2+ for tuning the efficacy of Ca2+-induced Ca2+ release in rat ventricular myocytes.
The Journal of physiology 2003;552(Pt 2):415-24.
2003: Jun Matsukawa; Kazuhisa Nakayama; Taku Nagao; Hidenori Ichijo; Tetsuro Urushidani
Role of ADP-ribosylation factor 6 (ARF6) in gastric acid secretion.
The Journal of biological chemistry 2003;278(38):36470-5.
2003: Shinji Yamaguchi; Boris S Zhorov; Katsuro Yoshioka; Taku Nagao; Hidenori Ichijo; Satomi Adachi-Akahane
Key roles of Phe1112 and Ser1115 in the pore-forming IIIS5-S6 linker of L-type Ca2+ channel alpha1C subunit (CaV 1.2) in binding of dihydropyridines and action of Ca2+ channel agonists.
Molecular pharmacology 2003;64(2):235-48.
2003: Hiroyuki Kobayashi; Takashi Miwa; Taku Nagao; Satomi Adachi-Akahane
Negative modulation of L-type Ca2+ channels via beta-adrenoceptor stimulation in guinea-pig detrusor smooth muscle cells.
European journal of pharmacology 2003;470(1-2):9-15.
2003: Masafumi Hagiwara; Satomi Adachi-Akahane; Taku Nagao
High-affinity binding of [3H]DTZ323 to the diltiazem-binding site of L-type Ca2+ channels.
European journal of pharmacology 2003;466(1-2):63-71.
2003: Ken Arai; Yoshiko Maruyama; Motohiro Nishida; Shihori Tanabe; Shuichi Takagahara; Tohru Kozasa; Yasuo Mori; Taku Nagao; Hitoshi Kurose
Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation.
Molecular pharmacology 2003;63(3):478-88.
2002: Yoshiko Maruyama; Motohiro Nishida; Yoshiyuki Sugimoto; Shihori Tanabe; Justin H Turner; Tohru Kozasa; Teiji Wada; Taku Nagao; Hitoshi Kurose
Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy.
Circulation research 2002;91(10):961-9.
2002: Haruko Futagawa; Hiroaki Takahashi; Taku Nagao; Satomi Adachi-Akahane
A carbamate-type cholinesterase inhibitor 2-sec-butylphenyl N-methylcarbamate insecticide blocks L-type Ca2+ channel in guinea pig ventricular myocytes.
Japanese journal of pharmacology 2002;90(1):12-20.
2002: Yoshiyuki Sugimoto; Reiko Fujisawa; Ryuji Tanimura; Anne-Laure Lattion; Susanna Cotecchia; Gozoh Tsujimoto; Taku Nagao; Hitoshi Kurose
Beta(1)-selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [(-)-RO363] differentially interacts with key amino acids responsible for beta(1)-selective binding in resting and active states.
The Journal of pharmacology and experimental therapeutics 2002;301(1):51-8.
2002: Yoshiko Mizukawa; Tomohiro Nishizawa; Taku Nagao; Ken Kitamura; Tetsuro Urushidani
Cellular distribution of parchorin, a chloride intracellular channel-related protein, in various tissues.
American journal of physiology. Cell physiology 2002;282(4):C786-95.
2002: Motohiro Nishida; Kevin L Schey; Shuichi Takagahara; Kenji Kontani; Toshiaki Katada; Yasuteru Urano; Tetsuo Nagano; Taku Nagao; Hitoshi Kurose
Activation mechanism of Gi and Go by reactive oxygen species.
The Journal of biological chemistry 2002;277(11):9036-42.
2002: Motohiro Nishida; Shuichi Takagahara; Yoshiko Maruyama; Yoshiyuki Sugimoto; Taku Nagao; Hitoshi Kurose
G beta gamma counteracts G alpha(q) signaling upon alpha(1)-adrenergic receptor stimulation.
Biochemical and biophysical research communications 2002;291(4):995-1000.
2002: Masafumi Isogaya; Taku Nagao; Hitoshi Kurose
Enhanced cAMP response of naturally occurring mutant of human beta3-adrenergic receptor.
Japanese journal of pharmacology 2002;88(3):314-8.
2002: Ryuichi Sato; Kenji Sakamoto; Jun Yamazaki; Taku Nagao
Differences in protective profiles of diltiazem isomers in ischemic and reperfused guinea pig hearts.
European journal of pharmacology 2002;434(3):125-31.
2001: N Omi; Taku Nagao; Tetsuro Urushidani
Phosphatidylinositol is essential determinant for K+ permeability involved in gastric proton pumping.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(3):G786-97.
2001: T Shiina; K i Arai; Ken Arai; Norihiro Yoshida; Tatsuya Haga; Taku Nagao; Hitoshi Kurose
Clathrin box in G protein-coupled receptor kinase 2.
The Journal of biological chemistry 2001;276(35):33019-26.
2001: K Akagi; Taku Nagao; Tetsuro Urushidani
Reconstitution of acid secretion in digitonin-permeabilized rabbit gastric glands. Identification of cytosolic regulatory factors.
The Journal of biological chemistry 2001;276(30):28171-8.
2001: K Hamada; Jun Yamazaki; Taku Nagao
Diltiazem ameliorates contractile dysfunction without shortening of action potential duration in ischemic heart of anesthetized dogs.
Japanese journal of pharmacology 2001;86(2):251-3.
2001: Junichi Takada; Setsuro Ibayashi; Taku Nagao; Hiroaki Ooboshi; Takanari Kitazono; Masatoshi Fujishima
Bradykinin mediates the acute effect of an angiotensin-converting enzyme inhibitor on cerebral autoregulation in rats.
Stroke; a journal of cerebral circulation 2001;32(5):1216-9.
2001: T Shiina; Taku Nagao; Hitoshi Kurose
Low affinity of beta1-adrenergic receptor for beta-arrestins explains the resistance to agonist-induced internalization.
Life sciences 2001;68(19-20):2251-7.
2001: Y Muto; Taku Nagao; Maki K Yamada; Katsuhiko Mikoshiba; Tetsuro Urushidani
A proposed mechanism for the potentiation of cAMP-mediated acid secretion by carbachol.
American journal of physiology. Cell physiology 2001;280(1):C155-65.
2000: Sachiko Yamaguchi; Yasushi Okamura; Taku Nagao; Satomi Adachi-Akahane
Serine residue in the IIIS5-S6 linker of the L-type Ca2+ channel alpha 1C subunit is the critical determinant of the action of dihydropyridine Ca2+ channel agonists.
The Journal of biological chemistry 2000;275(52):41504-11.
2000: Y Maruyama; Taku Nagao; Hitoshi Kurose
[Simplified method for gene transfer and expression by recombinant adenoviruses].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2000;116(6):359-70.
2000: Motohiro Nishida; Yoshiko Maruyama; R Tanaka; Kenji Kontani; Taku Nagao; Hitoshi Kurose
G alpha(i) and G alpha(o) are target proteins of reactive oxygen species.
Nature 2000;408(6811):492-5.
2000: Jiro Kitayama; Takanari Kitazono; Setsuro Ibayashi; Masanori Wakisaka; Y Watanabe; Masahiro Kamouchi; Taku Nagao; Masatoshi Fujishima
Role of phosphatidylinositol 3-kinase in acetylcholine-induced dilatation of rat basilar artery.
Stroke; a journal of cerebral circulation 2000;31(10):2487-93.
2000: Hiroyuki Kobayashi; Satomi Adachi-Akahane; Taku Nagao
Involvement of BK(Ca) channels in the relaxation of detrusor muscle via beta-adrenoceptors.
European journal of pharmacology 2000;404(1-2):231-8.
2000: T Shiina; A Kawasaki; Taku Nagao; Hitoshi Kurose
Interaction with beta-arrestin determines the difference in internalization behavor between beta1- and beta2-adrenergic receptors.
The Journal of biological chemistry 2000;275(37):29082-90.
2000: Kenji Sakamoto; M Ishikawa; K Koga; Tetsuro Urushidani; Taku Nagao
Energy preserving effect of l-cis diltiazem in isolated ischemic and reperfused guinea pig hearts: a 31P-NMR study.
Japanese journal of pharmacology 2000;83(3):225-32.
2000: T Nishizawa; Taku Nagao; Takeshi Iwatsubo; JG Forte; Tetsuro Urushidani
Molecular cloning and characterization of a novel chloride intracellular channel-related protein, parchorin, expressed in water-secreting cells.
The Journal of biological chemistry 2000;275(15):11164-73.
2000: Kimitoshi Sakamoto; Tetsuro Urushidani; Taku Nagao
Translocation of HSP27 to sarcomere induced by ischemic preconditioning in isolated rat hearts.
Biochemical and biophysical research communications 2000;269(1):137-42.
2000: Setsuro Ibayashi; Taku Nagao; Takanari Kitazono; Hiroaki Ooboshi; J Kitayama; Seizo Sadoshima; Masatoshi Fujishima
Calcium antagonist isradipine reduces metabolic alterations in acute cerebral ischemia in spontaneously hypertensive rats.
Neurochemical research 2000;25(3):349-55.
1999: K Akagi; Taku Nagao; Tetsuro Urushidani
Correlation between Ca(2+) oscillation and cell proliferation via CCK(B)/gastrin receptor.
Biochimica et biophysica acta 1999;1452(3):243-53.
1999: M Nishida; Tetsuro Urushidani; Kenji Sakamoto; Taku Nagao
L-cis diltiazem attenuates intracellular Ca(2+) overload by metabolic inhibition in guinea pig myocytes.
European journal of pharmacology 1999;385(2-3):225-30.
1999: Masafumi Isogaya; Yoshiyuki Sugimoto; R Tanimura; R Tanaka; Hideo Kikkawa; Taku Nagao; Hitoshi Kurose
Binding pockets of the beta(1)- and beta(2)-adrenergic receptors for subtype-selective agonists.
Molecular pharmacology 1999;56(5):875-85.
1999: K Nishioka; Taku Nagao; Tetsuro Urushidani
Correlation between acid secretion and proton pump activity during inhibition by the proton pump inhibitors omeprazole and pantoprazole.
Biochemical pharmacology 1999;58(8):1349-59.
1999: Hitoshi Kurose; M Nishida; Taku Nagao
[beta gamma subunit of heterotrimeric G protein as a new target molecule for drug development].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1999;114 Suppl 1():75P-80P.
1999: A Takesono; J Zahner; K J Blumer; Taku Nagao; Hitoshi Kurose
Negative regulation of alpha2-adrenergic receptor-mediated Gi signalling by a novel pathway.
The Biochemical journal 1999;343 Pt 1():77-85.
1999: Chiyuki Akiyama; Taku Nagao; Hitoshi Kurose
Analysis of domain responsible for desensitization of beta1-adrenergic receptor.
Japanese journal of pharmacology 1999;81(1):12-20.
1999: T Sato; H Kobayashi; Taku Nagao; Hitoshi Kurose
Ser203 as well as Ser204 and Ser207 in fifth transmembrane domain of the human beta2-adrenoceptor contributes to agonist binding and receptor activation.
British journal of pharmacology 1999;128(2):272-4.
1999: K Akagi; Taku Nagao; Tetsuro Urushidani
Responsiveness of beta-escin-permeabilized rabbit gastric gland model: effects of functional peptide fragments.
The American journal of physiology 1999;277(3 Pt 1):G736-44.
1999: Motohiro Nishida; Taku Nagao; Hitoshi Kurose
Activation of Rac1 increases c-Jun NH(2)-terminal kinase activity and DNA fragmentation in a calcium-dependent manner in rat myoblast cell line H9c2.
Biochemical and biophysical research communications 1999;262(2):350-4.
1999: M Nishida; Kenji Sakamoto; Tetsuro Urushidani; Taku Nagao
Treatment with l-cis diltiazem before reperfusion reduces infarct size in the ischemic rabbit heart in vivo.
Japanese journal of pharmacology 1999;80(4):319-25.
1999: R Sato; Jun Yamazaki; Taku Nagao
Temporal differences in actions of calcium channel blockers on K+ accumulation, cardiac function, and high-energy phosphate levels in ischemic guinea pig hearts.
The Journal of pharmacology and experimental therapeutics 1999;289(2):831-9.
1999: Y Sugita; Taku Nagao; Tetsuro Urushidani
Nonspecific effects of the pharmacological probes commonly used to analyze signal transduction in rabbit parietal cells.
European journal of pharmacology 1999;365(1):77-89.
1999: Taku Nagao
[Pharmacological evaluation of the development candidate].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1999;113(1):15-8.
1998: Kimitoshi Sakamoto; Tetsuro Urushidani; Taku Nagao
Translocation of HSP27 to cytoskeleton by repetitive hypoxia-reoxygenation in the rat myoblast cell line, H9c2.
Biochemical and biophysical research communications 1998;251(2):576-9.
1998: S Kanda; Satomi Adachi-Akahane; Taku Nagao
Functional interaction between benzothiazepine- and dihydropyridine binding sites of cardiac L-type Ca2+ channels.
European journal of pharmacology 1998;358(3):277-87.
1998: Hitoshi Kurose; E Takikawa; S Akahane; R Tanaka; Taku Nagao
[Functional analysis of G protein-coupled receptor kinase (beta ARK1) by intracellular immunization].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1998;112 Suppl 1():68P-72P.
1998: K Akagi; K Hasebe; K Watanabe; Taku Nagao; Tetsuro Urushidani
Gastric acid secretion is augmented by the replacement of extracellular Na+ with K+ or other ions.
Japanese journal of pharmacology 1998;78(2):147-59.
1998: Masafumi Isogaya; Y Yamagiwa; S Fujita; Yoshiyuki Sugimoto; Taku Nagao; Hitoshi Kurose
Identification of a key amino acid of the beta2-adrenergic receptor for high affinity binding of salmeterol.
Molecular pharmacology 1998;54(4):616-22.
1998: J Yamazaki; Kota Sato; F Ohara; Taku Nagao
Direct activation of endothelial NO pathway by Ba2+ in canine coronary artery.
British journal of pharmacology 1998;124(6):1149-58.
1998: K Hamada; J Yamazaki; Taku Nagao
Shortening of action potential duration is not prerequisite for cardiac protection by ischemic preconditioning or a KATP channel opener.
Journal of molecular and cellular cardiology 1998;30(7):1369-79.
1998: Kenji Sakamoto; Jun Yamazaki; Taku Nagao
5-hydroxydecanoate selectively reduces the initial increase in extracellular K+ in ischemic guinea-pig heart.
European journal of pharmacology 1998;348(1):31-5.
1998: K Toyoda; Koji Fujii; Setsuro Ibayashi; Takanari Kitazono; Taku Nagao; H Takaba; Masatoshi Fujishima
Attenuation and recovery of brain stem autoregulation in spontaneously hypertensive rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(3):305-10.
1998: Takanari Kitazono; Setsuro Ibayashi; Taku Nagao; Koji Fujii; T Kagiyama; Masatoshi Fujishima
Role of tyrosine kinase in dilator responses of rat basilar artery in vivo.
Hypertension 1998;31(3):861-5.
1998: K Hamada; Jun Yamazaki; Taku Nagao
Shortening of monophasic action potential duration during hyperkalemia and myocardial ischemia in anesthetized dogs.
Japanese journal of pharmacology 1998;76(2):149-54.
1998: Kota Sato; Jun Yamazaki; Taku Nagao
Modulatory role of endothelial calcium level in vascular tension of canine depolarized coronary arteries.
The American journal of physiology 1998;274(2 Pt 2):H494-9.
1998: Takanari Kitazono; Setsuro Ibayashi; Taku Nagao; T Kagiyama; Jiro Kitayama; Masatoshi Fujishima
Role of tyrosine kinase in serotonin-induced constriction of the basilar artery in vivo.
Stroke; a journal of cerebral circulation 1998;29(2):494-7; discussion 498.
1998: H Cai; H Yao; Setsuro Ibayashi; G Zhao; Takanari Kitazono; Taku Nagao; Masatoshi Fujishima
Effects of long-acting angiotensin-converting enzyme inhibitor, imidapril, on the lower limit of cerebral blood flow autoregulation in hypertensive rats.
European journal of pharmacology 1998;341(1):73-7.
1998: Hitoshi Kurose; Masafumi Isogaya; Hideo Kikkawa; Taku Nagao
Domains of beta1 and beta2 adrenergic receptors to bind subtype selective agonists.
Life sciences 1998;62(17-18):1513-7.
1998: Hideo Kikkawa; Masafumi Isogaya; Taku Nagao; Hitoshi Kurose
The role of the seventh transmembrane region in high affinity binding of a beta 2-selective agonist TA-2005.
Molecular pharmacology 1998;53(1):128-34.
1998: K Doi; Taku Nagao; K Kawakubo; Setsuro Ibayashi; K Aoyagi; Y Yano; C Yamamoto; K Kanamoto; Mitsuo Iida; Seizo Sadoshima; Masatoshi Fujishima
Calcitonin gene-related peptide affords gastric mucosal protection by activating potassium channel in Wistar rat.
Gastroenterology 1998;114(1):71-6.
1997: Tetsuro Urushidani; Taku Nagao
[Signal transduction and intracellular recruitment of gastric proton pump in the parietal cell].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1997;110(6):303-13.
1997: K Toyoda; Koji Fujii; Setsuro Ibayashi; Taku Nagao; Takanari Kitazono; Masatoshi Fujishima
Role of nitric oxide in regulation of brain stem circulation during hypotension.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(10):1089-96.
1997: Kenji Sakamoto; Jun Yamazaki; Taku Nagao
Diltiazem inhibits the late increase in extracellular potassium by maintaining glycolytic ATP synthesis during myocardial ischemia.
Journal of cardiovascular pharmacology 1997;30(4):424-30.
1997: K Akagi; Taku Nagao; Tetsuro Urushidani
Calcium oscillations in single cultured Chinese hamster ovary cells stably transfected with a cloned human cholecystokinin (CCK)B receptor.
Japanese journal of pharmacology 1997;75(1):33-42.
1997: K Toyoda; Koji Fujii; Setsuro Ibayashi; Takanari Kitazono; Taku Nagao; Masatoshi Fujishima
Role of ATP-sensitive potassium channels in brain stem circulation during hypotension.
The American journal of physiology 1997;273(3 Pt 2):H1342-6.
1997: Y Muto; Taku Nagao; Tetsuro Urushidani
The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell.
The Journal of pharmacology and experimental therapeutics 1997;282(3):1379-88.
1997: H Takaba; Taku Nagao; Hiroshi Yao; Takanari Kitazono; Setsuro Ibayashi; Masatoshi Fujishima
An ATP-sensitive potassium channel activator reduces infarct volume in focal cerebral ischemia in rats.
The American journal of physiology 1997;273(2 Pt 2):R583-6.
1997: Hideo Kikkawa; Hitoshi Kurose; Masafumi Isogaya; Y Sato; Taku Nagao
Differential contribution of two serine residues of wild type and constitutively active beta2-adrenoceptors to the interaction with beta2-selective agonists.
British journal of pharmacology 1997;121(6):1059-64.
1997: Tetsuro Urushidani; Y Muto; Taku Nagao; X Yao; JG Forte
ME-3407, a new antiulcer agent, inhibits acid secretion by interfering with redistribution of H(+)-K(+)-ATPase.
The American journal of physiology 1997;272(5 Pt 1):G1122-34.
1997: Junko Kurokawa; Satomi Adachi-Akahane; Taku Nagao
Effects of a novel, potent benzothiazepine Ca2+ channel antagonist, DTZ323, on guinea-pig ventricular myocytes.
European journal of pharmacology 1997;325(2-3):229-36.
1997: Y Sato; Hitoshi Kurose; Taku Nagao
Relationship between desensitization and downregulation of beta-adrenoceptors in cardiac tissues after prolonged in vivo infusion of T-0509, a beta 1-adrenoceptor agonist.
Japanese journal of pharmacology 1997;73(4):325-32.
1997: M Hagiwara; Satomi Adachi-Akahane; Taku Nagao
High-affinity binding of DTZ323, a novel derivative of diltiazem, to rabbit skeletal muscle L-type Ca++ channels.
The Journal of pharmacology and experimental therapeutics 1997;281(1):173-9.
1997: Tetsuro Urushidani; Taku Nagao
Ca2+-dependent membrane bound protein fraction from rabbit gastric mucosa contains a protein whose histidyl residue is phosphorylated.
Biochimica et biophysica acta 1997;1356(1):71-83.
1997: Junko Kurokawa; Satomi Adachi-Akahane; Taku Nagao
1,5-benzothiazepine binding domain is located on the extracellular side of the cardiac L-type Ca2+ channel.
Molecular pharmacology 1997;51(2):262-8.
1997: S Kanda; Junko Kurokawa; Satomi Adachi-Akahane; Taku Nagao
Diltiazem derivatives modulate the dihydropyridine-binding to intact rat ventricular myocytes.
European journal of pharmacology 1997;319(1):101-7.
1997: Takanari Kitazono; Setsuro Ibayashi; Taku Nagao; Koji Fujii; Masatoshi Fujishima
Role of Ca(2+)-activated K+ channels in acetylcholine-induced dilatation of the basilar artery in vivo.
British journal of pharmacology 1997;120(1):102-6.
1996: Y Sato; Hitoshi Kurose; Masafumi Isogaya; Taku Nagao
Molecular characterization of pharmacological properties of T-0509 for beta-adrenoceptors.
European journal of pharmacology 1996;315(3):363-7.
1996: Hiroaki Shimokawa; H Yasutake; Koji Fujii; M K Owada; R Nakaike; Yoshihiro Fukumoto; T Takayanagi; Taku Nagao; Kensuke Egashira; Masatoshi Fujishima; Akira Takeshita
The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation.
Journal of cardiovascular pharmacology 1996;28(5):703-11.
1996: T Kusayama; Jun Yamazaki; Taku Nagao
Flow dependence of nitric oxide-mediated pressure change in rat mesenteric beds with different tonus.
European journal of pharmacology 1996;312(3):301-7.
1996: H Takaba; Taku Nagao; Setsuro Ibayashi; Takanari Kitazono; Koji Fujii; Masatoshi Fujishima
Altered cerebrovascular response to a potassium channel opener in hypertensive rats.
Hypertension 1996;28(1):143-6.
1996: Yusuke Ohya; M Setoguchi; Koji Fujii; Taku Nagao; Isao Abe; Masatoshi Fujishima
Impaired action of levcromakalim on ATP-sensitive K+ channels in mesenteric artery cells from spontaneously hypertensive rats.
Hypertension 1996;27(6):1234-9.
1996: Jun Yamazaki; Tetsuro Urushidani; Taku Nagao
Barium activates rat cerebellar nitric oxide synthase.
Japanese journal of pharmacology 1996;70(4):351-4.
1996: K Shimasue; Tetsuro Urushidani; M Hagiwara; Taku Nagao
Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel.
European journal of pharmacology 1996;296(3):347-50.
1996: Taku Nagao; Setsuro Ibayashi; Seizo Sadoshima; Koji Fujii; K Fujii; Yusuke Ohya; Masatoshi Fujishima
Distribution and physiological roles of ATP-sensitive K+ channels in the vertebrobasilar system of the rabbit.
Circulation research 1996;78(2):238-43.
1995: Y Sato; Satomi Adachi-Akahane; P Prados; K Imai; Taku Nagao
Desensitization and selective down-regulation of rat cardiac beta 1-adrenoceptors by prolonged in vivo infusion of T-0509, a beta 1-adrenoceptor full agonist.
Japanese journal of pharmacology 1995;69(4):343-50.
1995: K Ohashi; Jun Yamazaki; Taku Nagao
Contractions and relaxations accompanied by endothelial nitric oxide production induced in the porcine coronary artery by Ca2+, Ba2+ and Sr2+.
European journal of pharmacology 1995;285(2):165-71.
1995: Y Kitagawa; Satomi Adachi-Akahane; Taku Nagao
Determination of beta-adrenoceptor subtype on rat isolated ventricular myocytes by use of highly selective beta-antagonists.
British journal of pharmacology 1995;116(1):1635-43.
1995: Seizo Sadoshima; Setsuro Ibayashi; Koji Fujii; Taku Nagao; H Sugimori; Masatoshi Fujishima
Inhibition of acetylcholinesterase modulates the autoregulation of cerebral blood flow and attenuates ischemic brain metabolism in hypertensive rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(5):845-51.
1995: H Tagami; Jun Yamazaki; Taku Nagao
Differential effects of selective beta 1-agonist stimulation on epi- and endocardial oxygen tension in anesthetized dogs.
Biological & pharmaceutical bulletin 1995;18(7):951-6.
1995: Jun Yamazaki; F Ohara; Y Harada; Taku Nagao
Barium and strontium can substitute for calcium in stimulating nitric oxide production in the endothelium of canine coronary arteries.
Japanese journal of pharmacology 1995;68(1):25-32.
1994: Hirofumi Tsuga; Kimihiko Kameyama; Tatsuya Haga; Hitoshi Kurose; Taku Nagao
Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2.
The Journal of biological chemistry 1994;269(51):32522-7.
1994: S Ikeda; Y Amano; Satomi Adachi-Akahane; Taku Nagao
Binding of [3H](+)-PN200-110 to aortic membranes from normotensive and spontaneously hypertensive rats.
European journal of pharmacology 1994;264(2):223-6.
1994: R Okuyama; Satomi Adachi-Akahane; Taku Nagao
Differential potentiation by depolarization of the effects of calcium antagonists on contraction and Ca2+ current in guinea-pig heart.
British journal of pharmacology 1994;113(2):451-6.
1994: T Kusayama; J Oka; H Yabana; Satomi Adachi-Akahane; Taku Nagao
Binding of a catechol derivative of denopamine (T-0509) and N-tert-butylnoradrenaline (Colterol) to beta 1- and beta 2-adrenoceptors.
Biological & pharmaceutical bulletin 1994;17(8):1023-7.
1994: Jun Yamazaki; T Sugimoto; H Yabana; Taku Nagao
Hemodynamic and coronary vasodilative properties of a selective and full beta 1-adrenoceptor agonist, T-0509, in comparison with isoproterenol in anesthesized dogs.
Journal of cardiovascular pharmacology 1994;24(2):209-15.
1994: K Imai; S Higashidate; P R Prados; Tomofumi Santa; Satomi Adachi-Akahane; Taku Nagao
Relation between blood pressure and plasma catecholamine concentration after administration of calcium antagonists to rats.
Biological & pharmaceutical bulletin 1994;17(7):907-10.
1994: H Sugimori; Setsuro Ibayashi; K Irie; Hiroaki Ooboshi; Taku Nagao; Koji Fujii; Seizo Sadoshima; Masatoshi Fujishima
Cerebral hemodynamics in hypertensive patients compared with normotensive volunteers. A transcranial Doppler study.
Stroke; a journal of cerebral circulation 1994;25(7):1384-9.
1994: Seizo Sadoshima; Taku Nagao; Setsuro Ibayashi; Masatoshi Fujishima
Inhibition of angiotensin-converting enzyme modulates the autoregulation of regional cerebral blood flow in hypertensive rats.
Hypertension 1994;23(6 Pt 1):781-5.
1994: Hitoshi Kurose; Taku Nagao
[Regulation of G proteins by receptors].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1994;103(6):273-84.
1994: Taku Nagao; Seizo Sadoshima; Setsuro Ibayashi; Y Takeya; Masatoshi Fujishima
Increase in extracranial atherosclerotic carotid lesions in patients with brain ischemia in Japan. An angiographic study.
Stroke; a journal of cerebral circulation 1994;25(4):766-70.
1994: P Prados; S Higashidate; K Imai; Y Sato; Taku Nagao
Sensitive determination of (-)-isoproterenol and (-)-(R)-1-(3,4- dihydroxyphenyl)-2-[(3,4-dimethoxyphenethyl)amino] ethanol (T-0509), a cardiotonic agent, in rat plasma utilizing a fully automated catecholamine analyser.
Biomedical chromatography : BMC 1994;8(1):49-51.
1994: S Higashidate; K Imai; P Prados; Satomi Adachi-Akahane; Taku Nagao
Relations between blood pressure and plasma norepinephrine concentrations after administration of diltiazem to rats: HPLC-peroxyoxalate chemiluminescence determination on an individual basis.
Biomedical chromatography : BMC 1994;8(1):19-21.
1993: H Watanabe; M Tateyama; Taku Nagao; S Ohta; Masaaki Hirobe; Hiraku Ono
Methamphetamine antagonistic property of (+)- and (-)-4-phenyltetrahydroisoquinoline in rat anococcygeus muscle.
European journal of pharmacology 1993;243(2):155-61.
1993: M Tateyama; Taku Nagao; S Ohta; Masaaki Hirobe; Hiraku Ono
4-Phenyltetrahydroisoquinoline, but not nomifensine or cocaine, inhibits methamphetamine-induced dopamine release.
European journal of pharmacology 1993;240(1):51-6.
1993: M Tateyama; S Ohta; Taku Nagao; Masaaki Hirobe; Hiraku Ono
Inhibitory effect of 4-phenyltetrahydroisoquinoline on locomotion and dopamine release induced by micro-injection of methamphetamine into the nucleus accumbens of the rat.
Neuropharmacology 1993;32(8):761-6.
1993: N Kamijo; Taku Nagao; Hiraku Ono
Depression of the monosynaptic reflex by apomorphine or bromocriptine is not mediated by D1/D2 receptors.
Neuropharmacology 1993;32(8):777-83.
1993: H Sugimori; Setsuro Ibayashi; Hiroaki Ooboshi; Taku Nagao; Koji Fujii; Seizo Sadoshima; Masatoshi Fujishima
[Age-related changes in intracranial artery velocity measured by transcranial Doppler sonography in normotensive, hypertensive and diabetic patients].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 1993;30(7):610-6.
1993: H Hashitani; G Chen; H Ono; N Seki; Y Li; Taku Nagao; H Suzuki
Electrophysiological comparison of the effects of MCI-154 on smooth muscles between mesenteric artery and vein of dogs.
General pharmacology 1993;24(2):333-40.
1993: M Tateyama; S Ohta; Taku Nagao; Masaaki Hirobe; Hiraku Ono
Effect of 4-phenyl-1,2,3,4-tetrahydroisoquinoline on ambulation induced by injection of methamphetamine into the nucleus accumbens in rats.
Neuropharmacology 1993;32(3):243-8.
1993: Satomi Adachi-Akahane; Y Amano; R Okuyama; Taku Nagao
Quaternary diltiazem can act from both sides of the membrane in ventricular myocytes.
Japanese journal of pharmacology 1993;61(3):263-6.
1993: Hiroshi Yao; Taku Nagao; Hiroaki Ooboshi; T Matsumoto; M Hirano; Tatsuo Nakahara; Seizo Sadoshima; Hideyuki Uchimura; Masatoshi Fujishima
Ischemia-induced changes in brain monoamine metabolism in aged spontaneously hypertensive rats.
Gerontology 1993;39(3):128-35.
1992: M Satoh; S Ohta; Taku Nagao; Masaaki Hirobe; H Fukuda; Hiraku Ono
Amphetamine-antagonistic property of 4-phenyltetrahydroisoquinoline: effect on noradrenaline release in spinal cord slices.
Japanese journal of pharmacology 1992;60(2):121-5.
1992: Jun Yamazaki; H Fukuda; Taku Nagao; Hiraku Ono
5-HT2/5-HT1C receptor-mediated facilitatory action on unit activity of ventral horn cells in rat spinal cord slices.
European journal of pharmacology 1992;220(2-3):237-42.
1992: Taku Nagao; Seizo Sadoshima; T Ishitsuka; K Kusuda; O Shiokawa; Setsuro Ibayashi; Masatoshi Fujishima
Effects of acute superior cervical ganglionectomy on cerebral blood flow and metabolism in stroke-prone spontaneously hypertensive rats subjected to cerebral ischaemia.
Clinical and experimental pharmacology & physiology 1992;19(7):489-93.
1992: Jun Yamazaki; Hiraku Ono; Taku Nagao
Stimulatory and inhibitory effects of serotonergic hallucinogens on spinal mono- and polysynaptic reflex pathways in the rat.
Neuropharmacology 1992;31(7):635-42.
1992: T Koga; Y Takata; K Kobayashi; Koji Fujii; Taku Nagao; Masatoshi Fujishima
Age-related changes in P2-purinergic receptors on vascular smooth muscle and endothelium.
Hypertension 1992;19(3):286-9.
1992: S Adachi; J Oka; Taku Nagao; H Fukuda
Cyclic AMP analog activates Na(+)-dependent inward currents in dissociated frog motoneurons.
Brain research 1992;573(2):349-52.
1992: S Adachi; J Oka; Taku Nagao; H Fukuda
Activation of beta-adrenergic receptor induces Na(+)-dependent inward currents in acutely dissociated motoneurons of bullfrog spinal cord.
Brain research 1992;571(1):79-88.
1991: Hiraku Ono; Y Hasebe; M Satoh; Taku Nagao; S Ohta; Masaaki Hirobe; H Fuduka
Amphetamine-antagonistic properties of 4-phenyl-1,2,3,4- tetrahydroisoquinoline: inhibition of spinal reflex-enhancing effects of methamphetamine, phenylethylamine and nomifensine.
Brain research 1991;564(2):319-22.
1991: S Ikeda; J Oka; Taku Nagao
Effects of four diltiazem stereoisomers on binding of d-cis-[3H]diltiazem and (+)-[3H]PN200-110 to rabbit T-tubule calcium channels.
European journal of pharmacology 1991;208(3):199-205.
1991: Jun Yamazaki; N Fujita; Taku Nagao
NG-monomethyl-L-arginine-induced pressor response at developmental and established stages in spontaneously hypertensive rats.
The Journal of pharmacology and experimental therapeutics 1991;259(1):52-7.
1991: Taku Nagao; Seizo Sadoshima; Masahiro Kamouchi; Masatoshi Fujishima
Cromakalim dilates rat cerebral arteries in vitro.
Stroke; a journal of cerebral circulation 1991;22(2):221-4.
1989: K Komori; Taku Nagao; G L Zhang; J K Ibengwe; M Fujioka; H Suzuki
Bunazosin, an alpha 1-adrenoceptor blocker, differentially releases co-transmitters in dog mesenteric vessels.
European journal of pharmacology 1989;164(1):111-20.
1989: O Shiokawa; Seizo Sadoshima; Y Okada; Taku Nagao; Masatoshi Fujishima
Alpha- and beta-adrenergic receptors of noradrenergic innervation modulate the lower limits of cerebral and cerebellar blood flow autoregulation in spontaneously hypertensive rats.
Gerontology 1989;35(2-3):106-12.
1988: N Seki; Taku Nagao; K Komori; H Suzuki
Alpha and beta adrenoceptor blocking action of carvedilol in the canine mesenteric artery and vein.
The Journal of pharmacology and experimental therapeutics 1988;246(3):1116-22.
1988: Hiroshi Yao; Seizo Sadoshima; T Ishitsuka; Taku Nagao; Masatoshi Fujishima; T Tsutsumi; Hideyuki Uchimura
Massive striatal dopamine release in acute cerebral ischemia in rats.
Experientia 1988;44(6):506-8.
1988: Taku Nagao; H Suzuki
Effects of alpha, beta-methylene ATP on electrical responses produced by ATP and nerve stimulation in smooth muscle cells of the guinea-pig mesenteric artery.
General pharmacology 1988;19(6):799-805.
1987: Taku Nagao; H Suzuki
Modulation by noradrenaline and yohimbine of noradrenergic transmission in the guinea-pig mesenteric artery.
European journal of pharmacology 1987;144(3):287-97.
1987: Taku Nagao; H Suzuki
Non-neural electrical responses of smooth muscle cells of the rabbit basilar artery to electrical field stimulation.
The Japanese journal of physiology 1987;37(3):497-513.