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Toshiro Nagasawa

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Mayuko Koshino; Daisuke Kudou; Yasushi Okoshi; Naoshi Obara; Seiichi Simizu; Harumi Y Mukai; Kazumi Suzukawa; Yuichi Hasegawa; Hiroshi Kojima; Toshiro Nagasawa; Shigeru Chiba
[Successful treatment with rituximab in a patient with refractory thrombotic thrombocytopenic purpura refractory to plasma exchange].
Y Kozuma; S Yuki; H Ninomiya; Toshiro Nagasawa; Hiroshi Kojima
Caspase activation is involved in early megakaryocyte differentiation but not in platelet production from megakaryocytes.
Taro Ishigaki; Kazuhiro Sudo; Takashi Hiroyama; Kenichi Miharada; Haruhiko Ninomiya; Shigeru Chiba; Toshiro Nagasawa; Yukio Nakamura
Human hematopoietic stem cells can survive in vitro for several months.

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2010: Mayuko Koshino; Daisuke Kudou; Yasushi Okoshi; Naoshi Obara; Seiichi Simizu; Harumi Y Mukai; Kazumi Suzukawa; Yuichi Hasegawa; Hiroshi Kojima; Toshiro Nagasawa; Shigeru Chiba
[Successful treatment with rituximab in a patient with refractory thrombotic thrombocytopenic purpura refractory to plasma exchange].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2010;51(2):127-31.
2009: Y Kozuma; S Yuki; H Ninomiya; Toshiro Nagasawa; Hiroshi Kojima
Caspase activation is involved in early megakaryocyte differentiation but not in platelet production from megakaryocytes.
Leukemia 2009;23(6):1080-6.
2009: Taro Ishigaki; Kazuhiro Sudo; Takashi Hiroyama; Kenichi Miharada; Haruhiko Ninomiya; Shigeru Chiba; Toshiro Nagasawa; Yukio Nakamura
Human hematopoietic stem cells can survive in vitro for several months.
Advances in hematology 2009;2009():936761.
2008: Naoshi Obara; Norio Suzuki; Kibom Kim; Toshiro Nagasawa; Shigehiko Imagawa; Masayuki Yamamoto
Repression via the GATA box is essential for tissue-specific erythropoietin gene expression.
Blood 2008;111(10):5223-32.
2008: Manabu Kusakabe; Kazumi Suzukawa; Toru Nanmoku; Naoshi Obara; Yasushi Okoshi; Harumi Y Mukai; Yuichi Hasegawa; Hiroshi Kojima; Yasushi Kawakami; Haruhiko Ninomiya; Toshiro Nagasawa
Detection of the STAT5B-RARA fusion transcript in acute promyelocytic leukemia with the normal chromosome 17 on G-banding.
European journal of haematology 2008;80(5):444-7.
2008: Kenichi Miharada; Takashi Hiroyama; Kazuhiro Sudo; Inaho Danjo; Toshiro Nagasawa; Yukio Nakamura
Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells.
Journal of cellular physiology 2008;215(2):526-37.
2008: Takashi Hiroyama; Kazuhiro Sudo; Naoko Aoki; Kenichi Miharada; Inaho Danjo; Tsuyoshi Fujioka; Toshiro Nagasawa; Yukio Nakamura
Human umbilical cord-derived cells can often serve as feeder cells to maintain primate embryonic stem cells in a state capable of producing hematopoietic cells.
Cell biology international 2008;32(1):1-7.
2007: Yukitaka Katsura; Kazumi Suzukawa; Toru Nanmoku; Noriko Nemoto; Takayuki Machino; Naoshi Obara; Yasushi Okoshi; Harumi Y Mukai; Yuichi Hasegawa; Hiroshi Kojima; Yasushi Kawakami; Toshiro Nagasawa
Myelodysplastic syndrome accompanied by basophilia and eosinophilia with t(5;12)(q31;p13).
Cancer genetics and cytogenetics 2007;178(1):85-8.
2007: Noriko Nemoto; Kazumi Suzukawa; Seiichi Shimizu; Atsushi Shinagawa; Naoko Takei; Tomohiko Taki; Yasuhide Hayashi; Hiroshi Kojima; Yasushi Kawakami; Toshiro Nagasawa
Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23).
Genes, chromosomes & cancer 2007;46(9):813-9.
2007: Takahisa Tarumoto; Shigehiko Imagawa; Makoto Kobayashi; Aki Hirayama; Keiya Ozawa; Toshiro Nagasawa
L-arginine administration reverses anemia associated with renal disease.
International journal of hematology 2007;86(2):126-9.
2007: Y Kozuma; Hiroshi Kojima; S Yuki; H Suzuki; Toshiro Nagasawa
Continuous expression of Bcl-xL protein during megakaryopoiesis is post-translationally regulated by thrombopoietin-mediated Akt activation, which prevents the cleavage of Bcl-xL.
Journal of thrombosis and haemostasis : JTH 2007;5(6):1274-82.
2007: Takayuki Machino; Yasushi Okoshi; S Kaneko; Naoshi Obara; Harumi Y Mukai; Kazumi Suzukawa; Yuichi Hasegawa; Yoriko Yamashita; Naoyoshi Mori; Hiroshi Kojima; Toshiro Nagasawa
Hepatosplenic alphabeta T-cell lymphoma successfully treated with allogeneic bone marrow transplantation.
Bone marrow transplantation 2007;39(8):513-4.
2007: Hidekazu Maruyama; Shigeyuki Watanabe; Taizo Kimura; Jingyan Liang; Toshiro Nagasawa; Masafumi Onodera; Kazutaka Aonuma; Iwao Yamaguchi
Granulocyte colony-stimulating factor prevents progression of monocrotaline-induced pulmonary arterial hypertension in rats.
Circulation journal : official journal of the Japanese Circulation Society 2007;71(1):138-43.
2006: Hideharu Muto; Shin Kaneko; Takayuki Machino; Yasushi Okoshi; Harumi Y Mukai; Kazumi Suzukawa; Yuichi Hasegawa; Shigehiko Imagawa; Hiroshi Kojima; Yukio Ishii; Shigemi Hitomi; Toshiro Nagasawa
Quinupristin/dalfopristin and voriconazole controlled Staphylococcus epidermidis pneumonia and chronic necrotizing aspergillosis in a patient with severe lung degradation consequent to multiple treatments for Hodgkin's lymphoma.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2006;12(6):391-5.
2006: Hiroshi Kojima; M Moroi; S M Jung; S Goto; N Tamura; Y Kozuma; Kazumi Suzukawa; Toshiro Nagasawa
Characterization of a patient with glycoprotein (GP) VI deficiency possessing neither anti-GPVI autoantibody nor genetic aberration.
Journal of thrombosis and haemostasis : JTH 2006;4(11):2433-42.
2006: Ken Matsumoto; Shigehiko Imagawa; Naoshi Obara; Norio Suzuki; Satoru Takahashi; Toshiro Nagasawa; Masayuki Yamamoto
2-Oxoglutarate downregulates expression of vascular endothelial growth factor and erythropoietin through decreasing hypoxia-inducible factor-1alpha and inhibits angiogenesis.
Journal of cellular physiology 2006;209(2):333-40.
2006: Kenichi Miharada; Takashi Hiroyama; Kazuhiro Sudo; Toshiro Nagasawa; Yukio Nakamura
Efficient enucleation of erythroblasts differentiated in vitro from hematopoietic stem and progenitor cells.
Nature biotechnology 2006;24(10):1255-6.
2006: Kazuhiro Sugiyama; Yuichi Hasegawa; Toshiro Nagasawa; Shigemi Hitomi
Exposure of medical staff to Strongyloides stercolaris from a patient with disseminated strongyloidiasis.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2006;12(4):217-9.
2006: Hiroshi Kojima; Yuna Katsuoka; Yukitaka Katsura; Sachie Suzuki; Kazumi Suzukawa; Yuichi Hasegawa; Toshiro Nagasawa
Successful treatment of a patient with POEMS syndrome by tandem high-dose chemotherapy with autologous CD34+ purged stem cell rescue.
International journal of hematology 2006;84(2):182-5.
2006: K Yamagata; Kojiro Onizawa; T Yanagawa; Yuichi Hasegawa; Hiroshi Kojima; Toshiro Nagasawa; H Yoshida
A prospective study to evaluate a new dental management protocol before hematopoietic stem cell transplantation.
Bone marrow transplantation 2006;38(3):237-42.
2006: Takashi Hiroyama; Kenichi Miharada; Naoko Aoki; Tsuyoshi Fujioka; Kazuhiro Sudo; Inaho Danjo; Toshiro Nagasawa; Yukio Nakamura
Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells.
Experimental hematology 2006;34(6):760-9.
2006: Naoko Takei; Kazumi Suzukawa; Harumi Y Mukai; Takayoshi Itoh; Yasushi Okoshi; Yasuhiro Yoda; Toshiro Nagasawa
Therapy-related acute myeloid leukemia 6 years after clonal detection of inv(11)(q21q23) and MLL gene rearrangement.
International journal of hematology 2006;83(3):247-51.
2006: Kenichi Miharada; Takashi Hiroyama; Kazuhiro Sudo; Toshiro Nagasawa; Yukio Nakamura
Refinement of cytokine use in the in vitro expansion of erythroid cells.
Human cell 2006;19(1):30-7.
2005: Kenichi Miharada; Takashi Hiroyama; Kazuhiro Sudo; Toshiro Nagasawa; Yukio Nakamura
Lipocalin 2 functions as a negative regulator of red blood cell production in an autocrine fashion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(13):1881-3.
2005: Atsushi Shinagawa; Hiroshi Kojima; Michael C Berndt; Shin Kaneko; Kazumi Suzukawa; Yuichi Hasegawa; Osamu Shigeta; Toshiro Nagasawa
Characterization of a myeloma patient with a life-threatening hemorrhagic diathesis: presence of a lambda dimer protein inhibiting shear-induced platelet aggregation by binding to the A1 domain of von Willebrand factor.
Thrombosis and haemostasis 2005;93(5):889-96.
2005: Shin Kaneko; Toshiro Nagasawa; Hiromitsu Nakauchi; Masafumi Onodera
An in vivo assay for retrovirally transduced human peripheral T lymphocytes using nonobese diabetic/severe combined immunodeficiency mice.
Experimental hematology 2005;33(1):35-41.
2005: Yasushi Okoshi; Satoko Tahara-Hanaoka; Chigusa Nakahashi; Shin-ichiro Honda; Akitomo Miyamoto; Hiroshi Kojima; Toshiro Nagasawa; Kazuko Shibuya; Akira Shibuya
Requirement of the tyrosines at residues 258 and 270 of MAIR-I in inhibitory effect on degranulation from basophilic leukemia RBL-2H3.
International immunology 2005;17(1):65-72.
2004: Yoko Nakano; Shigehiko Imagawa; Ken Matsumoto; Christian Stockmann; Naoshi Obara; Norio Suzuki; Takeshi Doi; Tatsuhiko Kodama; Satoru Takahashi; Toshiro Nagasawa; Masayuki Yamamoto
Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease.
Blood 2004;104(13):4300-7.
2004: Hiroshi Kojima; Yuichi Hasegawa; Kazumi Suzukawa; Harumi Y Mukai; Shin Kaneko; Toshitaka Kobayashi; Masaharu Kamoshita; Atsushi Shinagawa; Takuya Komeno; Tsunehiko Komatsu; Shoichi Mitsuhashi; Yasuhiro Kawachi; Yoriko Yamashita; Naoyoshi Mori; Toshiro Nagasawa
Clinicopathological features and prognostic factors of Japanese patients with "peripheral T-cell lymphoma, unspecified" diagnosed according to the WHO classification.
Leukemia research 2004;28(12):1287-92.
2004: Chikashi Yoshida; Kazumi Suzukawa; Yukitaka Katsura; Seiichi Shimizu; Harumi Y Mukai; Yuichi Hasegawa; Shigehiko Imagawa; Hiroshi Kojima; Toshiro Nagasawa
T-cell acute lymphoblastic leukemia with add(1)(p36) and del(12)(p11) following acute myelocytic leukemia with partial deletion of 9p.
Cancer genetics and cytogenetics 2004;150(1):62-5.
2004: Chikashi Yoshida; Hiroshi Kojima; Tatsuo Iijima; Yukitaka Katsura; Seiichi Shimizu; Kazumi Suzukawa; Harumi Y Mukai; Yuichi Hasegawa; Masato Abei; Toshiro Nagasawa
Association of non-alcoholic steatohepatitis (NASH) with chronic neutrophilic leukemia.
European journal of haematology 2004;72(3):225-8.
2004: Chikashi Yoshida; Hiroshi Kojima; Taro Ishigaki; Yukitaka Katsura; Shin Kaneko; Kazumi Suzukawa; Yuichi Hasegawa; Yasuhiro Kawachi; Fujio Otsuka; Toshiro Nagasawa
Association of pyoderma gangrenosum and sterile osteomyelitis in a patient having myelodysplastic syndrome with der(1;7)(q10;q10).
European journal of haematology 2004;72(2):149-53.
2004: Shigehiko Imagawa; Y Yamaguchi; K Ogawa; Naoshi Obara; Norio Suzuki; Masayuki Yamamoto; Toshiro Nagasawa
Interleukin-6 and tumor necrosis factor-alpha in patients with obstructive sleep apnea-hypopnea syndrome.
Respiration; international review of thoracic diseases 2004;71(1):24-9.
2003: Naoshi Obara; Shigehiko Imagawa; Yoko Nakano; Masayuki Yamamoto; Toshihiro Noguchi; Toshiro Nagasawa
Hematological aspects of a novel 9-aminoanthracycline, amrubicin.
Cancer science 2003;94(12):1104-6.
2003: Hiroshi Kojima; Hirotaka Kanada; Seiichi Shimizu; Emi Kasama; Kazuko Shibuya; Hiromitsu Nakauchi; Toshiro Nagasawa; Akira Shibuya
CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells.
The Journal of biological chemistry 2003;278(38):36748-53.
2003: Shigehiko Imagawa; Yoko Nakano; Naoshi Obara; Norio Suzuki; Takeshi Doi; Tatsuhiko Kodama; Toshiro Nagasawa; Masayuki Yamamoto
A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1742-4.
2003: Hiroshi Kojima; Seiichi Shimizu; Chikashi Yoshida; Yukitaka Katsura; Kazumi Suzukawa; Harumi Y Mukai; Yuichi Hasgawa; Shigehiko Imagawa; Naoyoshi Mori; Toshiro Nagasawa
Rapidly progressive Lennert's lymphoma terminating in fulminant hepatic failure.
Leukemia & lymphoma 2003;44(8):1409-12.
2003: Noriko Chikatsu; Hiroshi Kojima; Kazumi Suzukawa; Atsushi Shinagawa; Toshiro Nagasawa; Hiroaki Ozawa; Yoriko Yamashita; Naoyoshi Mori
ALK+, CD30-, CD20- large B-cell lymphoma containing anaplastic lymphoma kinase (ALK) fused to clathrin heavy chain gene (CLTC).
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2003;16(8):828-32.
2003: Harumi Y Mukai; Yasushi Okoshi; Seiichi Shimizu; Yukitaka Katsura; Naoko Takei; Yuichi Hasegawa; Hiroshi Kojima; Naoyoshi Mori; Toshiro Nagasawa
Successful treatment of a patient with subcutaneous panniculitis-like T-cell lymphoma with high-dose chemotherapy and total body irradiation.
European journal of haematology 2003;70(6):413-6.
2003: Naoshi Obara; Shigehiko Imagawa; Yoko Nakano; Norio Suzuki; Masayuki Yamamoto; Toshiro Nagasawa
Suppression of erythropoietin gene expression by cadmium depends on inhibition of HIF-1, not stimulation of GATA-2.
Archives of toxicology 2003;77(5):267-73.
2003: Yukitaka Katsura; Kazumi Suzukawa; Hiroshi Kojima; Chikashi Yoshida; Seiichi Shimizu; Harumi Y Mukai; Yuichi Hasegawa; Shigehiko Imagawa; Naoyoshi Mori; Toshiro Nagasawa
Cytotoxic T-cell lymphoma arising in Behçet disease.
International journal of hematology 2003;77(3):282-5.
2003: Seiichi Shimizu; Yuna Tamagawa; Hiroshi Kojima; Naoyoshi Mori; Michio Nagata; Masayuki Noguchi; Toshiro Nagasawa
Simultaneous development of lymphoplasmacytic lymphoma and diffuse large B-cell lymphoma--analyses of the clonal relatedness by sequencing CDR3 in immunoglobulin heavy chain genes.
European journal of haematology 2003;70(2):119-24.
2003: Hitoshi Horigome; Takashi Murakami; Takeshi Isobe; Toshiro Nagasawa; Akira Matsui
Soluble P-selectin and thrombomodulin-protein C-Protein S pathway in cyanotic congenital heart disease with secondary erythrocytosis.
Thrombosis research 2003;112(4):223-7.
2003: Hiroshi Kojima; Naoko Takei; Y Mukai; Yuichi Hasegawa; Kazumi Suzukawa; M Nagata; M Noguchi; Naoyoshi Mori; Toshiro Nagasawa
Hemophagocytic syndrome as the primary clinical symptom of Hodgkin's disease.
Annals of hematology 2003;82(1):53-6.
2002: Harumi Y Mukai; Yuichi Hasegawa; Hiroshi Kojima; Yasushi Okoshi; Naoko Takei; Yoriko Yamashita; Toshiro Nagasawa; Naoyoshi Mori
Nodal CD8 positive cytotoxic T-cell lymphoma: a distinct clinicopathological entity.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2002;15(11):1131-9.
2002: Hiroshi Kojima; M Abei; Naoko Takei; Y Mukai; Yuichi Hasegawa; T Iijima; Toshiro Nagasawa
Fatal reactivation of hepatitis B virus following cytotoxic chemotherapy for acute myelogenous leukemia: fibrosing cholestatic hepatitis.
European journal of haematology 2002;69(2):101-4.
2002: Yasushi Okoshi; Shigehiko Imagawa; Masato Higuchi; Chikashi Yoshida; Seiichi Shimizu; Harumi Y Mukai; Takuya Komeno; Yuichi Hasegawa; Haruhiko Ninomiya; Hiroshi Kojima; Toshiro Nagasawa
A patient with acquired pure red cell aplasia showing a positive antiglobulin test and the presence of inhibitor against erythroid precursors.
Internal medicine (Tokyo, Japan) 2002;41(7):589-92.
2002: Shigehiko Imagawa; Norio Suzuki; Ken Ohmine; Naoshi Obara; Harumi Y Mukai; Keiya Ozawa; Masayuki Yamamoto; Toshiro Nagasawa
GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter.
International journal of hematology 2002;75(4):376-81.
2002: Hitoshi Horigome; Yuji Hiramatsu; Osamu Shigeta; Toshiro Nagasawa; Akira Matsui
Overproduction of platelet microparticles in cyanotic congenital heart disease with polycythemia.
Journal of the American College of Cardiology 2002;39(6):1072-7.
2002: Shigehiko Imagawa; Takahisa Tarumoto; Norio Suzuki; Harumi Y Mukai; Yuichi Hasegawa; Masato Higuchi; Tomohiro Neichi; Keiya Ozawa; Masayuki Yamamoto; Toshiro Nagasawa
L-arginine rescues decreased erythropoietin gene expression by stimulating GATA-2 with L-NMMA.
Kidney international 2002;61(2):396-404.
2001: Shigehiko Imagawa; Y Yamaguchi; Masato Higuchi; Tomohiro Neichi; Yuichi Hasegawa; Harumi Y Mukai; Norio Suzuki; Masayuki Yamamoto; Toshiro Nagasawa
Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea--hypopnea syndrome.
Blood 2001;98(4):1255-7.
2001: Atsushi Shinagawa; Hiroshi Kojima; T Kobayashi; K Kawada; Toshiro Nagasawa
Lupus anticoagulant-like activity observed in a dimeric lambda protein produced by myeloma cells.
International journal of hematology 2001;73(4):526-31.
2001: Hiroshi Kojima; Atsushi Shinagawa; S Shimizu; H Kanada; Masahiko Hibi; T Hirano; Toshiro Nagasawa
Role of phosphatidylinositol-3 kinase and its association with Gab1 in thrombopoietin-mediated up-regulation of platelet function.
Experimental hematology 2001;29(5):616-22.
2001: Yasushi Okoshi; Seiichi Shimizu; Hiroshi Kojima; Naoshi Obara; Harumi Y Mukai; Takuya Komeno; Yuichi Hasegawa; Naoyoshi Mori; Toshiro Nagasawa
Detection of minimal residual disease in a patient having acute myelogenous leukemia with t(16;21)(p11;q22) treated by allogeneic bone marrow transplantation.
Acta haematologica 2001;105(1):45-8.
2001: T Urasaki; Jun Takasaki; Toshiro Nagasawa; Haruhiko Ninomiya
Pivotal role of 5-lipoxygenase in the activation of human eosinophils: platelet-activating factor and interleukin-5 induce CD69 on eosinophils through the 5-lipoxygenase pathway.
Journal of leukocyte biology 2001;69(1):105-12.
2000: Hiroshi Kojima; Harumi Y Mukai; Atsushi Shinagawa; Chikashi Yoshida; M Kamoshita; Takuya Komeno; Yuichi Hasegawa; Yoriko Yamashita; Naoyoshi Mori; Toshiro Nagasawa
Clinicopathological analyses of 5 Japanese patients with CD56+ primary cutaneous lymphomas.
International journal of hematology 2000;72(4):477-83.
2000: Haruhiko Ninomiya; Y Kawashima; Toshiro Nagasawa
Inhibition of complement-mediated haemolysis in paroxysmal nocturnal haemoglobinuria by heparin or low-molecular weight heparin.
British journal of haematology 2000;109(4):875-81.
2000: Hiroshi Kojima; A Bai; Harumi Y Mukai; M Hori; Takuya Komeno; Yuichi Hasegawa; Haruhiko Ninomiya; Naoyoshi Mori; Toshiro Nagasawa
Chronic myelomonocytic leukemia derived from a possible common progenitor of monocytes and natural killer cells.
Leukemia & lymphoma 2000;37(5-6):617-21.
2000: Harumi Y Mukai; Hiroshi Kojima; Kazumi Suzukawa; M Hori; Takuya Komeno; Yuichi Hasegawa; Haruhiko Ninomiya; Naoyoshi Mori; Toshiro Nagasawa
Nasal natural killer cell lymphoma in a post-renal transplant patient.
Transplantation 2000;69(7):1501-3.
2000: T Urasaki; Jun Takasaki; Toshiro Nagasawa; Haruhiko Ninomiya
Induction of the activation-related antigen CD69 on human eosinophils by type IIA phospholipase A2.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2000;49(4):177-83.
2000: Yuichi Hasegawa; A Bai; Hiroshi Kojima; Takuya Komeno; Haruhiko Ninomiya; Toshiro Nagasawa
Priming effects of macrophage colony-stimulating factor on monocytic leukemia cells in combination with chemotherapy: induction of programmed cell death in vivo.
Leukemia & lymphoma 2000;36(5-6):589-93.
2000: Y Hasegawa; Toshiro Nagasawa
[Thrombotic thrombocytopenic purpura].
Ryōikibetsu shōkōgun shirīzu 2000;(31):152-4.
2000: M Kamoshita; Toshiro Nagasawa
[Immune megakaryocytopenia].
Ryōikibetsu shōkōgun shirīzu 2000;(31):146-51.
2000: Susumu Nishimura; Satoru Takahashi; Takashi Kuroha; Naruyoshi Suwabe; Toshiro Nagasawa; Cecelia D Trainor; Masayuki Yamamoto
A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene.
Molecular and cellular biology 2000;20(2):713-23.
1999: Naoshi Obara; Y Ohkoshi; Harumi Y Mukai; Takuya Komeno; Yuichi Hasegawa; Hiroshi Kojima; Haruhiko Ninomiya; Toshiro Nagasawa
[T-cell prolymphocytic leukemia with CD4+8+25+ phenotype in a patient presenting with venous thrombosis in the lower leg].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1999;40(11):1187-92.
1999: Yuichi Hasegawa; T Itoh; Yuna Tamagawa; Takuya Komeno; Hiroshi Kojima; Haruhiko Ninomiya; Y Yatabe; Naoyoshi Mori; Toshiro Nagasawa
Non-Hodgkin's lymphoma followed by plasmacytoma, both arising in A thyroid gland with Hashimoto's disease.
Leukemia & lymphoma 1999;35(5-6):613-8.
1999: Y Ohkoshi; Haruhiko Ninomiya; Harumi Y Mukai; N Mochizuki; M Hori; Toshiro Nagasawa; T Jikuya; Y Saida
Pseudoaneurysm of the subclavian artery due to Xanthomonas pneumonia in a patient with acute myeloid leukemia: its rupture treated by transcatheter coil embolization.
Internal medicine (Tokyo, Japan) 1999;38(8):671-4.
1999: Harumi Y Mukai; Hiroshi Kojima; Kazumi Suzukawa; M Hori; Takuya Komeno; Yuichi Hasegawa; Haruhiko Ninomiya; Naoyoshi Mori; Toshiro Nagasawa
High-dose chemotherapy with peripheral blood stem cell rescue in blastoid natural killer cell lymphoma.
Leukemia & lymphoma 1999;32(5-6):583-8.
1999: A Bai; Hiroshi Kojima; M Hori; N Nara; Takuya Komeno; Yuichi Hasegawa; Haruhiko Ninomiya; T Abe; Toshiro Nagasawa
Priming with G-CSF effectively enhances low-dose Ara-C-induced in vivo apoptosis in myeloid leukemia cells.
Experimental hematology 1999;27(2):259-65.
1999: M Ino; Sohji Nagase; Toshiro Nagasawa; Akio Koyama; S Tachibana
The outer membrane protein I of Pseudomonas aeruginosa PAO1, a possible pollutant of dialysate in hemodialysis, induces cytokines in mouse bone marrow cells.
Nephron 1999;82(4):324-30.
1999: T Urasaki; Haruhiko Ninomiya; Jun Takasaki; Y Kawauchi; Toshiro Nagasawa; Yasuhiko Masuho
Cytosolic phospholipase A2, increased and activated in the eosinophils of patients with hypereosinophilic syndrome in vivo, is involved in the augmented release of leukotriene C4.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48(1):36-40.
1999: M Osada; Takuya Komeno; K Todokoro; M Takizawa; Hiroshi Kojima; Kazumi Suzukawa; Haruhiko Ninomiya; T Abe; Toshiro Nagasawa
Immature megakaryocytes undergo apoptosis in the absence of thrombopoietin.
Experimental hematology 1999;27(1):131-8.
1998: Kazumi Suzukawa; Hiroshi Kojima; Naoyoshi Mori; Harumi Y Mukai; M Hori; Takuya Komeno; Yuichi Hasegawa; Haruhiko Ninomiya; Toshiro Nagasawa
Anaplastic large-cell lymphoma of null-cell type with multiple bone involvement.
Annals of hematology 1998;77(6):287-90.
1998: Satoru Takahashi; Takuya Komeno; Naruyoshi Suwabe; Keigyou Yoh; Osamu Nakajima; Susumu Nishimura; Takashi Kuroha; Toshiro Nagasawa; Masayuki Yamamoto
Role of GATA-1 in proliferation and differentiation of definitive erythroid and megakaryocytic cells in vivo.
Blood 1998;92(2):434-42.
1998: Takashi Kuroha; Satoru Takahashi; Takuya Komeno; Ken Itoh; Toshiro Nagasawa; Masayuki Yamamoto
Ablation of Nrf2 function does not increase the erythroid or megakaryocytic cell lineage dysfunction caused by p45 NF-E2 gene disruption.
Journal of biochemistry 1998;123(3):376-9.
1998: Kazumi Suzukawa; Hiroshi Kojima; Toshiro Nagasawa
[Anaplastic large cell lymphoma].
Ryōikibetsu shōkōgun shirīzu 1998;(22 Pt 3):298-300.
1998: M Hori; Toshiro Nagasawa
[Intravascular lymphoma (IVL)].
Ryōikibetsu shōkōgun shirīzu 1998;(22 Pt 3):294-7.
1998: Toshiro Nagasawa
[Amegakaryocytic thrombocytopenia].
Ryōikibetsu shōkōgun shirīzu 1998;(21 Pt 2):342-6.
1998: Y Hasegawa; Toshiro Nagasawa
[Thrombocytopenia and neutropenia].
Ryōikibetsu shōkōgun shirīzu 1998;(21 Pt 2):329-31.
1997: Harumi Y Mukai; Haruhiko Ninomiya; Toshiro Nagasawa; T Abe
Elevated serum levels of eosinophil major basic protein in patients with myeloproliferative disorders without eosinophilia.
International journal of hematology 1997;66(2):197-202.
1997: Yuichi Hasegawa; Haruhiko Ninomiya; M Kamoshita; K Ohtani; T Kobayashi; Hiroshi Kojima; Toshiro Nagasawa; T Abe
Interstitial pneumonitis related to granulocyte colony-stimulating factor administration following chemotherapy for elderly patients with non-Hodgkin's lymphoma.
Internal medicine (Tokyo, Japan) 1997;36(5):360-4.
1997: Haruhiko Ninomiya; Yuichi Hasegawa; Toshiro Nagasawa; T Abe
Excess soluble urokinase-type plasminogen activator receptor in the plasma of patients with paroxysmal nocturnal hemoglobinuria inhibits cell-associated fibrinolytic activity.
International journal of hematology 1997;65(3):285-91.
1997: Atsushi Shinagawa; T Itoh; Takuya Komeno; T Komatsu; Yuichi Hasegawa; T Kobayashi; H Kozima; Haruhiko Ninomiya; Toshiro Nagasawa; T Abe
[Allopurinol induced pancytopenia in a patient with myeloproliferative disorder].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1997;38(1):64-71.
1996: Harumi Y Mukai; Hiroshi Kojima; K Todokoro; T Tahara; T Kato; Yuichi Hasegawa; T Kobayashi; Haruhiko Ninomiya; Toshiro Nagasawa; T Abe
Serum thrombopoietin (TPO) levels in patients with amegakaryocytic thrombocytopenia are much higher than those with immune thrombocytopenic purpura.
Thrombosis and haemostasis 1996;76(5):675-8.
1996: Takuya Komeno; Haruhiko Ninomiya; T Itoh; T Fujita; Toshiro Nagasawa; T Abe
Hemolytic anemia associated with myotonic muscular dystrophy.
Internal medicine (Tokyo, Japan) 1996;35(9):746-8.
1996: Takuya Komeno; K Ohtani; Yuichi Hasegawa; A Shinagawa; Harumi Y Mukai; T Komatsu; Toshiro Nagasawa; T Abe
[Appearance of cytoplasmic processes of megakaryocytes in the peripheral blood in a Munchausen syndrome with factitious anemia].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1996;37(9):848-52.
1996: T Hagiwara; Toshiro Nagasawa; H Nagahisa; M Takizawa; M Osada; T Abe
Expression of adhesion molecules on cytoplasmic processes of human megakaryocytes.
Experimental hematology 1996;24(6):690-5.
1996: Takuya Komeno; T Itoh; K Ohtani; M Kamoshita; Yuichi Hasegawa; M Hori; T Kobayashi; Toshiro Nagasawa; T Abe
Disseminated nontuberculous mycobacteriosis caused by mycobacterium kansasii in a patient with myelodysplastic syndrome.
Internal medicine (Tokyo, Japan) 1996;35(4):323-6.
1996: H Nagahisa; Y Nagata; T Ohnuki; M Osada; Toshiro Nagasawa; T Abe; Kazuo Todokoro
Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation.
Blood 1996;87(4):1309-16.
1996: Harumi Y Mukai; Haruhiko Ninomiya; S Mitsuhashi; Yuichi Hasegawa; Toshiro Nagasawa; T Abe
Thromboembolism in a patient with transient eosinophilia.
Annals of hematology 1996;72(2):93-5.
1996: T Kobayashi; Toshiro Nagasawa; S Mitsuhashi; Yuichi Hasegawa; Hiroshi Kojima; Haruhiko Ninomiya; Naoyoshi Mori; T Abe
Clinicopathological characteristics of primary Ki-1 anaplastic large cell lymphoma.
International journal of hematology 1996;63(1):41-50.
1996: T Ito; Hiroshi Kojima; K Otani; Takuya Komeno; S Mitsuhashi; Yuichi Hasegawa; T Kobayashi; Haruhiko Ninomiya; Toshiro Nagasawa; T Abe
Chronic neutrophilic leukemia associated with monoclonal gammopathy of undetermined significance.
Acta haematologica 1996;95(2):140-3.
1995: Takuya Komeno; Haruhiko Ninomiya; T Itoh; Yuichi Hasegawa; T Kobayashi; N Mori; Toshiro Nagasawa; T Abe
CD34-positive blastoma in a patient with idiopathic myelofibrosis.
Internal medicine (Tokyo, Japan) 1995;34(10):1035-7.
1995: Yuichi Hasegawa; Toshiro Nagasawa; M Kamoshita; Takuya Komeno; T Itoh; Haruhiko Ninomiya; T Abe
Effects of anti-platelet glycoprotein Ib and/or IIb/IIIa autoantibodies on the size of megakaryocytes in patients with immune thrombocytopenia.
European journal of haematology 1995;55(3):152-7.
1995: Toshiro Nagasawa; Yuichi Hasegawa; M Kamoshita; K Ohtani; Takuya Komeno; T Itoh; A Shinagawa; Hiroshi Kojima; Haruhiko Ninomiya; T Abe
Megakaryopoiesis in patients with cyclic thrombocytopenia.
British journal of haematology 1995;91(1):185-90.
1995: K Ohtani; Haruhiko Ninomiya; Yuichi Hasegawa; T Kobayashi; Hiroshi Kojima; Toshiro Nagasawa; T Abe
Clinical significance of elevated soluble interleukin-6 receptor levels in the sera of patients with plasma cell dyscrasias.
British journal of haematology 1995;91(1):116-20.
1995: Y Nagata; H Nagahisa; Y Aida; K Okutomi; Toshiro Nagasawa; Kazuo Todokoro
Thrombopoietin induces megakaryocyte differentiation in hematopoietic progenitor FDC-P2 cells.
The Journal of biological chemistry 1995;270(34):19673-5.
1995: Harumi Y Mukai; Haruhiko Ninomiya; K Ohtani; Toshiro Nagasawa; T Abe
Major basic protein binding to thrombomodulin potentially contributes to the thrombosis in patients with eosinophilia.
British journal of haematology 1995;90(4):892-9.
1995: Hiroshi Kojima; Takuya Komeno; A Shinagawa; Y Hasegawa; T Kobayashi; H Ninomiya; Toshiro Nagasawa; T Abe
CD3+, CD56+ large granular lymphocyte leukemia.
Blood 1995;85(12):3762.
1995: Toshiro Nagasawa; Yuichi Hasegawa; Takuya Komeno; T Itoh; Haruhiko Ninomiya; T Abe
Simultaneous measurements of megakaryocyte-associated IgG (MAIgG) and platelet-associated IgG (PAIgG) in chronic idiopathic thrombocytopenic purpura.
European journal of haematology 1995;54(5):314-20.
1995: S Mitsuhashi; Toshiro Nagasawa; M Kamoshita; K Otani; Yuichi Hasegawa; Hiroshi Kojima; Haruhiko Ninomiya; M Nakazawa; T Abe
[Minimally differentiated hypoplastic leukemia].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1995;36(2):115-20.
1995: M Kamoshita; K Suzukawa; T Kobayashi; Yuichi Hasegawa; Y Satoh; Haruhiko Ninomiya; Toshiro Nagasawa; T Abe
[von Recklinghausen's disease complicated by macroglobulinemia, malignant schwannoma and pheochromocytoma].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1995;36(1):59-62.
1994: Hiroshi Kojima; K Suzukawa; Y Yatabe; M Hori; Toshiro Nagasawa; T Abe
Establishment of a new natural killer (NK) cell line, TKS-1, from a patient with aggressive type of large granular lymphocyte (LGL) leukemia.
Leukemia 1994;8(11):1999-2004.
1994: M Hori; S Mitsuhashi; T Kobayashi; Toshiro Nagasawa; N Mori; M Miwa; T Abe
CD30-positive lymphoma in human T-cell leukaemia virus type 1 carrier without monoclonal integration of HTLV-1.
British journal of haematology 1994;88(2):419-20.
1994: M Hoshi; Toshiro Nagasawa; T Abe; T Satoh; Y Mitsui
Maturation of human megakaryocytic cell line (CMK-7) on the human umbilical vein endothelial cell (EC) monolayer.
International journal of hematology 1994;59(3):191-9.
1993: Hiroshi Kojima; M Hori; A Shibuya; Toshiro Nagasawa; M Miwa; T Abe
Successful treatment of a patient with adult T-cell leukemia by daily oral administration of low-dose etoposide. Decrease in the amount of HTLV-I proviral DNA revealed by the polymerase chain reaction method.
Cancer 1993;72(12):3614-7.
1993: S Mitsuhashi; Haruhiko Ninomiya; A Shibuya; Hiroshi Kojima; Toshiro Nagasawa; A Ohsaka; T Watanabe; S Kawachi; N Watanabe; H Ishida
[Effect of THP-CVP regimen for elderly patients with malignant lymphoma].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1993;34(12):1532-9.
1993: Y Sato; S Mituhashi; K Otani; M Kamoshita; Yuichi Hasegawa; Haruhiko Ninomiya; Toshiro Nagasawa; T Abe
[A study of hypoplastic myelodysplastic syndrome].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1993;34(11):1431-7.
1993: K Suzukawa; Haruhiko Ninomiya; S Mitsuhashi; I Anno; Toshiro Nagasawa; T Abe
Demonstration of the deposition of hemosiderin in the kidneys of patients with paroxysmal nocturnal hemoglobinuria by magnetic resonance imaging.
Internal medicine (Tokyo, Japan) 1993;32(9):686-90.
1993: K Shibuya; Haruhiko Ninomiya; Y Muraki; Toshiro Nagasawa; T Abe
Deficiency of glycosyl phosphatidylinositol-anchored proteins in polymorphonuclear leukocytes from patients with paroxysmal nocturnal hemoglobinuria with low-grade hemolysis.
International journal of hematology 1993;58(1-2):15-20.
1993: Haruhiko Ninomiya; Y Muraki; K Shibuya; Toshiro Nagasawa; T Abe
Induction of Fc gamma R-III (CD16) expression on neutrophils affected by paroxysmal nocturnal haemoglobinuria by administration of granulocyte colony-stimulating factor.
British journal of haematology 1993;84(3):497-503.
1993: Toshiro Nagasawa; H Yanagisawa; Yuichi Hasegawa; H Kanma; T Abe
Polycythemia associated with primary systemic amyloidosis: elevated levels of hemopoietic factors and cytokines.
American journal of hematology 1993;43(1):57-60.
1993: Toshiro Nagasawa
[Megakaryopoiesis in chronic myeloproliferative disorders].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1993;34(5):551-6.
1993: M Kamoshita; K Ohtani; Yuichi Hasegawa; Y Satoh; H Kozima; A Shibuya; Haruhiko Ninomiya; Toshiro Nagasawa; Y Matsunaga; T Abe
[Human parvovirus B19-induced aplastic crisis in an elderly man with intestinal hemorrhage].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1993;34(4):493-5.
1993: Yuichi Hasegawa; Toshiro Nagasawa; Hiroshi Kojima; A Shibuya; Haruhiko Ninomiya; T Abe
[Treatment of elderly patients with chronic idiopathic thrombocytopenic purpura].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1993;34(4):460-4.
1993: A Shibuya; Hiroshi Kojima; K Shibuya; K Nagayoshi; Toshiro Nagasawa; Hiromitsu Nakauchi
Enrichment of interleukin-2-responsive natural killer progenitors in human bone marrow.
Blood 1993;81(7):1819-26.
1992: T Kobayashi; Toshiro Nagasawa; T Abe; N Mori
[Morphological and immunohistochemical analysis of Ki-1 lymphoma].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1992;33(9):1183-90.
1992: T Kobayashi; Y Sato; Yuichi Hasegawa; Toshiro Nagasawa; Y Yoda; T Abe
Multiple myeloma complicated by congestive heart failure following first administration of recombinant alpha-interferon.
Internal medicine (Tokyo, Japan) 1992;31(7):936-40.
1992: A Shibuya; Y Muraki; Y Satoh; T Kobayashi; Hiroshi Kojima; Toshiro Nagasawa; T Abe; Junji Tomiyama; H Kudoh; Y Adachi
[Clinicopathological study of 6 cases of mantle zone lymphoma].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1992;33(6):770-5.
1992: Y Muraki; T Kobayashi; Hiroshi Kojima; A Shibuya; Toshiro Nagasawa; T Abe; N Mori
[Anorexia nervosa with neutropenia--response of neutrophils to G-CSF].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1992;33(3):328-32.
1991: Kazuo Todokoro; S Kuramochi; Toshiro Nagasawa; T Abe; Y Ikawa
Isolation of a cDNA encoding a potential soluble receptor for human erythropoietin.
Gene 1991;106(2):283-4.
1991: H Natsuda; Y Muraki; T Kobayashi; H Kozima; A Shibuya; Toshiro Nagasawa; T Abe
[Adult T cell lymphoma/leukemia with alopecia, huge tumors of scalp and wide destruction of cerebral bone].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1991;32(5):537-41.
1991: Toshiro Nagasawa; K Satoh; T Abe
Thrombopoietic factor enhances murine megakaryopoiesis induced by recombinant erythropoietin.
International journal of hematology 1991;54(2):159-64.
1990: K Satoh; Toshiro Nagasawa; T Abe
Simultaneous assay for megakaryocyte colony-stimulating factor and megakaryocyte potentiator and its application.
The Journal of laboratory and clinical medicine 1990;116(2):162-71.
1990: Toshiro Nagasawa; T Kobayashi; Y Satoh; H Yanagisawa; M Nakazawa; T Abe
[The relationship between responsiveness to splenectomy and clinical course after splenectomy in chronic idiopathic thrombocytopenic purpura (ITP)].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(7):922-8.
1990: T Hanada; I Ono; Toshiro Nagasawa
Childhood cyclic neutropenia treated with recombinant human granulocyte colony stimulating factor.
British journal of haematology 1990;75(1):135-7.
1990: Toshiro Nagasawa; T Orita; J Matsushita; M Tsuchiya; T Neichi; I Imazeki; N Imai; N Ochi; H Kanma; T Abe
Thrombopoietic activity of human interleukin-6.
FEBS letters 1990;260(2):176-8.
1990: Hiroshi Kojima; Yuichi Hasegawa; T Ikegami; Toshiro Nagasawa; T Abe
[Chronic myelogenous leukemia with marked thrombocytosis--comparison with essential thrombocythemia with Ph1 in its megakaryokinetics].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(1):35-40.
1989: Junji Tomiyama; Y Hasegawa; Toshiro Nagasawa; T Abe; H Horiguchi; T Ogata
Bacillus cereus septicemia associated with rhabdomyolysis and myoglobinuric renal failure.
Japanese journal of medicine 1989;28(2):247-50.
1988: A Shibuya; Haruhiko Ninomiya; M Nakazawa; Toshiro Nagasawa; Y Yoda; T Abe
Oxymetholone therapy in patients with familial antithrombin III deficiency.
Thrombosis and haemostasis 1988;60(3):495-7.
1988: Toshiro Nagasawa; T Neichi; K Satoh; M Nakazawa; T Abe
In vitro regulatory mechanisms for cytoplasmic maturation of murine megakaryocytes derived from colony-forming units megakaryocyte (CFU-M).
Experimental hematology 1988;16(8):667-73.
1988: T Hanada; K Koike; T Takeya; Toshiro Nagasawa; Y Matsunaga; H Takita
Human parvovirus B19-induced transient pancytopenia in a child with hereditary spherocytosis.
British journal of haematology 1988;70(1):113-5.
1987: T Hanada; K Saito; Toshiro Nagasawa; T Kabashima; S Nakahara; A Okuyama; H Takita
Intravenous gammaglobulin therapy for thromboneutropenic neonates of mothers with systemic lupus erythematosus.
European journal of haematology 1987;38(5):400-4.