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Hirokazu Nagawa

Research Profile

Disorders

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Anatomy

Chemicals & Drugs

Physiology

Gene Expression Regulation, Neoplastic

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Kumiko Hongo; Manabu Kaneko; Kazushige Kawai; Joji Kitayama; Koji Murono; Hirokazu Nagawa; Takako Nirei; Kazuhito Sasaki; Eiji Sunami; Noriko Tada; Koki Takahashi; Nelson H Tsuno; Masaya Hiyoshi; Toshiaki Watanabe
Hypoxia enhances colon cancer migration and invasion through promotion of epithelial-mesenchymal transition.
Kumiko Hongo; Shinsuke Kazama; Hirokazu Nagawa; Eiji Sunami; Koki Takahashi; Nelson H Tsuno; Joji Kitayama
Immunohistochemical detection of CD133 is associated with tumor regression grade after chemoradiotherapy in rectal cancer.
Kumiko Hongo; Manabu Kaneko; Kazushige Kawai; Joji Kitayama; Takeshi Nishikawa; Kazuhito Sasaki; Yasutaka Shuno; Eiji Sunami; Koki Takahashi; Junichiro Tanaka; Nelson H Tsuno; Masaya Hiyoshi; Hirokazu Nagawa
CD133(-) cells, derived from a single human colon cancer cell line, are more resistant to 5-fluorouracil (FU) than CD133(+) cells, dependent on the β1-integrin signaling.

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All Publications

2013: Kumiko Hongo; Manabu Kaneko; Kazushige Kawai; Joji Kitayama; Koji Murono; Hirokazu Nagawa; Takako Nirei; Kazuhito Sasaki; Eiji Sunami; Noriko Tada; Koki Takahashi; Nelson H Tsuno; Masaya Hiyoshi; Toshiaki Watanabe
Hypoxia enhances colon cancer migration and invasion through promotion of epithelial-mesenchymal transition.
The Journal of surgical research 2013;182(1):75-84.
2012: Kumiko Hongo; Shinsuke Kazama; Hirokazu Nagawa; Eiji Sunami; Koki Takahashi; Nelson H Tsuno; Joji Kitayama
Immunohistochemical detection of CD133 is associated with tumor regression grade after chemoradiotherapy in rectal cancer.
Medical oncology (Northwood, London, England) 2012;29(4):2849-57.
2012: Kumiko Hongo; Manabu Kaneko; Kazushige Kawai; Joji Kitayama; Takeshi Nishikawa; Kazuhito Sasaki; Yasutaka Shuno; Eiji Sunami; Koki Takahashi; Junichiro Tanaka; Nelson H Tsuno; Masaya Hiyoshi; Hirokazu Nagawa
CD133(-) cells, derived from a single human colon cancer cell line, are more resistant to 5-fluorouracil (FU) than CD133(+) cells, dependent on the β1-integrin signaling.
The Journal of surgical research 2012;175(2):278-88.
2012: Toshiaki Watanabe; Shinsuke Kazama; Hirokazu Nagawa
A 1cm distal bowel margin is safe for rectal cancer after preoperative radiotherapy.
Hepato-gastroenterology 2012;59(116):1068-74.
2012: Hideyo Miyato; Joji Kitayama; Hirokazu Nagawa
Vagus nerve preservation results in visceral fat maintenance after distal gastrectomy.
Hepato-gastroenterology 2012;59(116):1299-301.
2012: Koji Yasuda; Kazushige Kawai; Hirokazu Nagawa; Eiji Sunami; Joji Kitayama
Laboratory blood data have a significant impact on tumor response and outcome in preoperative chemoradiotherapy for advanced rectal cancer.
Journal of gastrointestinal cancer 2012;43(2):236-43.
2012: Hideyo Miyato; Akio Hidemura; Hironori Ishigami; Shoichi Kaisaki; Joji Kitayama; Hirokazu Nagawa
Vagus nerve preservation selectively restores visceral fat volume in patients with early gastric cancer who underwent gastrectomy.
The Journal of surgical research 2012;173(1):60-7.
2012: Yumiko Satoh; Yasuhiro Seto; Hiroshi Uozaki; Yutaka Yatomi; Hiromitsu Yokota; Masashi Fukayama; Kentaro Kitano; Joji Kitayama; Kazuhiko Mori; Hirokazu Nagawa; Hiroki Sasaki; Daiya Takai
Analysis for the combination expression of CK20, FABP1 and MUC2 is sensitive for the prediction of peritoneal recurrence in gastric cancer.
Japanese journal of clinical oncology 2012;42(2):148-52.
2011: Shinsuke Kazama; Joji Kitayama; Ken Mori; Junken Aoki; Hirokazu Nagawa
Immunohistochemical detection of autotaxin (ATX)/lysophospholipase D (lysoPLD) in submucosal invasive colorectal cancer.
Journal of gastrointestinal cancer 2011;42(4):204-11.
2011: Hiroaki Nozawa; Shinsuke Saito; Eiji Sunami; Kentaro Yazawa; Takamitsu Kanazawa; Kazushige Kawai; Shinsuke Kazama; Joji Kitayama; Ken Mori; Hirokazu Nagawa
[FOLFOX as adjuvant chemotherapy after curative resection of distant metastatic lesions in patients with colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2011;38(10):1627-32.
2011: Koji Yasuda; Hirokazu Nagawa; Takako Nirei; Nelson Hirokazu Tsuno; Joji Kitayama
Intratumoral injection of interleukin-2 augments the local and abscopal effects of radiotherapy in murine rectal cancer.
Cancer science 2011;102(7):1257-63.
2011: Toshiaki Watanabe; Yoko Yamamoto; Tadashi Yokoyama; Keijiro Nozawa; Toshiaki Tanaka; Mamoru Watanabe; Yohichi Ajioka; Kiyoshi Eshima; Toshifumi Hibi; Hisae Iinuma; Hiroki Ikeuchi; Soichiro Ishihara; Takamitsu Kanazawa; Takashi Kobunai; Tsuyoshi Konishi; Keiji Matsuda; Tetsuichiro Muto; Hirokazu Nagawa
Predicting ulcerative colitis-associated colorectal cancer using reverse-transcription polymerase chain reaction analysis.
Clinical colorectal cancer 2011;10(2):134-41.
2011: Kazushige Kawai; Nelson H Tsuno; Joji Kitayama; Eiji Sunami; Koki Takahashi; Hirokazu Nagawa
Catechin inhibits adhesion and migration of peripheral blood B cells by blocking CD11b.
Immunopharmacology and immunotoxicology 2011;33(2):391-7.
2011: Baker S Habeeb; Joji Kitayama; Hirokazu Nagawa
Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells.
Cancer science 2011;102(5):999-1006.
2011: Soichiro Ishihara; Toshiaki Watanabe; Hirokazu Nagawa
Free colonic perforation in a patient with Crohn's disease and loop ileostomy: report of a case.
International surgery 2011;96(2):159-61.
2011: Mikiko Nagayoshi; Tetsushi Taguchi; Tsuyoshi Takato; Hiroyuki Koyama; Tetsuro Miyata; Hirokazu Nagawa
Enhanced neovascular formation in a novel hydrogel matrix consisting of citric Acid and collagen.
Annals of vascular diseases 2011;4(3):196-203.
2011: Yasutaka Shuno; Eiji Sunami; Nelson H Tsuno; Giichiro Tsurita; Keisuke Hata; Masaya Hiyoshi; Kazushige Kawai; Joji Kitayama; Tetsu Kojima; Masaru Shinozaki; Hirokazu Nagawa
Is surveillance endoscopy necessary after colectomy in ulcerative colitis?
ISRN gastroenterology 2011;2011():509251.
2011: Hiroaki Nozawa; Shinsuke Saito; Eiji Sunami; Kentaro Yazawa; Takamitsu Kanazawa; Kazushige Kawai; Shinsuke Kazama; Joji Kitayama; Ken Mori; Hirokazu Nagawa
FOLFOX as adjuvant chemotherapy after curative resection of distant metastases in patients with colorectal cancer.
Oncology 2011;80(1-2):84-91.
2011: K Yasuda; Hirokazu Nagawa; Takako Nirei; Eiji Sunami; Joji Kitayama
Density of CD4(+) and CD8(+) T lymphocytes in biopsy samples can be a predictor of pathological response to chemoradiotherapy (CRT) for rectal cancer.
Radiation oncology (London, England) 2011;6():49.
2011: Joji Kitayama; Koji Yasuda; Kazushige Kawai; Eiji Sunami; Hirokazu Nagawa
Circulating lymphocyte is an important determinant of the effectiveness of preoperative radiotherapy in advanced rectal cancer.
BMC cancer 2011;11():64.
2011: Toshiaki Watanabe; Takashi Kobunai; Hiroki Ikeuchi; Yoko Yamamoto; Keiji Matsuda; Soichiro Ishihara; Keijiro Nozawa; Hisae Iinuma; Takamitsu Kanazawa; Toshiaki Tanaka; Tadashi Yokoyama; Tsuyoshi Konishi; Kiyoshi Eshima; Yoichi Ajioka; Toshifumi Hibi; Mamoru Watanabe; Tetsuichiro Muto; Hirokazu Nagawa
RUNX3 copy number predicts the development of UC-associated colorectal cancer.
International journal of oncology 2011;38(1):201-7.
2011: Takao Kamei; Joji Kitayama; Hironori Yamaguchi; Daisuke Soma; Shigenobu Emoto; Tomohiro Konno; Kazuhiko Ishihara; Hironori Ishigami; Shoichi Kaisaki; Hirokazu Nagawa
Spatial distribution of intraperitoneally administrated paclitaxel nanoparticles solubilized with poly (2-methacryloxyethyl phosphorylcholine-co n-butyl methacrylate) in peritoneal metastatic nodules.
Cancer science 2011;102(1):200-5.
2011: Kazushige Kawai; Joji Kitayama; Nelson H Tsuno; Eiji Sunami; Hirokazu Nagawa
Hyperfibrinogenemia after preoperative chemoradiotherapy predicts poor response and poor prognosis in rectal cancer.
International journal of colorectal disease 2011;26(1):45-51.
2010: Soichiro Ishihara; Toshiaki Watanabe; Tomomichi Kiyomatsu; Koji Yasuda; Hirokazu Nagawa
Prognostic significance of response to preoperative radiotherapy, lymph node metastasis, and CEA level in patients undergoing total mesorectal excision of rectal cancer.
International journal of colorectal disease 2010;25(12):1417-25.
2010: Naoyuki Yoshikawa; Nelson H Tsuno; Yurai Okaji; Kazushige Kawai; Yasutaka Shuno; Hirokazu Nagawa; Noriko Oshima; Koki Takahashi
Isoprenoid geranylgeranylacetone inhibits human colon cancer cells through induction of apoptosis and cell cycle arrest.
Anti-cancer drugs 2010;21(9):850-60.
2010: Hiroharu Yamashita; Keisuke Hata; Hironori Yamaguchi; Giichiro Tsurita; Kanako Wake; Soichi Watanabe; Masao Taki; Shoogo Ueno; Hirokazu Nagawa
Short-term exposure to a 1439-MHz TDMA signal exerts no estrogenic effect in rats.
Bioelectromagnetics 2010;31(7):573-5.
2010: Takeshi Nishikawa; Nelson H Tsuno; Yurai Okaji; Eiji Sunami; Yasutaka Shuno; Kazuhito Sasaki; Kumiko Hongo; Manabu Kaneko; Masaya Hiyoshi; Kazushige Kawai; Joji Kitayama; Koki Takahashi; Hirokazu Nagawa
The inhibition of autophagy potentiates anti-angiogenic effects of sulforaphane by inducing apoptosis.
Angiogenesis 2010;13(3):227-38.
2010: Kensuke Otani; Joji Kitayama; Takao Kamei; Daisuke Soma; Hideyo Miyato; Toshimasa Yamauchi; Takashi Kadowaki; Hirokazu Nagawa
Adiponectin receptors are downregulated in human gastric cancer.
Journal of gastroenterology 2010;45(9):918-27.
2010: Toshiaki Watanabe; Takashi Kobunai; Yoko Yamamoto; Takamitsu Kanazawa; Tsuyoshi Konishi; Toshiaki Tanaka; Keiji Matsuda; Soichiro Ishihara; Keijiro Nozawa; Kiyoshi Eshima; Tetsuichiro Muto; Hirokazu Nagawa
Prediction of liver metastasis after colorectal cancer using reverse transcription-polymerase chain reaction analysis of 10 genes.
European journal of cancer (Oxford, England : 1990) 2010;46(11):2119-26.
2010: Yasutaka Shuno; Nelson H Tsuno; Yurai Okaji; Takeshi Tsuchiya; Daisuke Sakurai; Takeshi Nishikawa; Naoyuki Yoshikawa; Kazuhito Sasaki; Kumiko Hongo; Giichiro Tsurita; Eiji Sunami; Joji Kitayama; Katsushi Tokunaga; Koki Takahashi; Hirokazu Nagawa
Id1/Id3 knockdown inhibits metastatic potential of pancreatic cancer.
The Journal of surgical research 2010;161(1):76-82.
2010: Tsuyoshi Konishi; Toshiaki Watanabe; Hirokazu Nagawa; Masatoshi Oya; Masashi Ueno; Hiroya Kuroyanagi; Yoshiya Fujimoto; Takashi Akiyoshi; Toshiharu Yamaguchi; Tetsuichiro Muto
Treatment of colorectal carcinoids: A new paradigm.
World journal of gastrointestinal surgery 2010;2(5):153-6.
2010: Masahiro Kato; Joji Kitayama; Hironori Yamaguchi; Junichi Sanuki; Shoichi Kaisaki; Hirokazu Nagawa
[Three cases of metastatic breast cancer effectively treated with S-1 therapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(5):903-6.
2010: Tsuyoshi Konishi; Toshiaki Watanabe; Hirokazu Nagawa; Masatoshi Oya; Masashi Ueno; Hiroya Kuroyanagi; Yoshiya Fujimoto; Takashi Akiyoshi; Toshiharu Yamaguchi; Tetsuichiro Muto
Preoperative chemoradiation and extended pelvic lymphadenectomy for rectal cancer: Two distinct principles.
World journal of gastrointestinal surgery 2010;2(4):95-100.
2010: Takeshi Nishikawa; Nelson H Tsuno; Yasutaka Shuno; Kazuhito Sasaki; Kumiko Hongo; Yurai Okaji; Eiji Sunami; Joji Kitayama; Koki Takahashi; Hirokazu Nagawa
Antiangiogenic effect of a selective 5-HT4 receptor agonist.
The Journal of surgical research 2010;159(2):696-704.
2010: Kensuke Otani; Joji Kitayama; Koji Yasuda; Yasunori Nio; Masato Iwabu; Shinichi Okudaira; Junken Aoki; Toshimasa Yamauchi; Takashi Kadowaki; Hirokazu Nagawa
Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice.
Cancer letters 2010;288(2):177-82.
2010: Takeshi Nishikawa; Nelson H Tsuno; Yurai Okaji; Yasutaka Shuno; Kazuhito Sasaki; Kumiko Hongo; Eiji Sunami; Joji Kitayama; Koki Takahashi; Hirokazu Nagawa
Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells.
Annals of surgical oncology 2010;17(2):592-602.
2010: Hironori Ishigami; Joji Kitayama; Shoichi Kaisaki; Hironori Yamaguchi; Hiroharu Yamashita; Shigenobu Emoto; Hirokazu Nagawa
Phase I study of biweekly intravenous paclitaxel plus intraperitoneal cisplatin and paclitaxel for gastric cancer with peritoneal metastasis.
Oncology 2010;79(3-4):269-72.
2010: Kazuhito Sasaki; Nelson H Tsuno; Eiji Sunami; Giichiro Tsurita; Kazushige Kawai; Yurai Okaji; Takeshi Nishikawa; Yasutaka Shuno; Kumiko Hongo; Masaya Hiyoshi; Manabu Kaneko; Joji Kitayama; Koki Takahashi; Hirokazu Nagawa
Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells.
BMC cancer 2010;10():370.
2010: Joji Kitayama; K Yasuda; Kazushige Kawai; Eiji Sunami; Hirokazu Nagawa
Circulating lymphocyte number has a positive association with tumor response in neoadjuvant chemoradiotherapy for advanced rectal cancer.
Radiation oncology (London, England) 2010;5():47.
2010: Joji Kitayama; Hironori Ishigami; Shoichi Kaisaki; Akio Hidemura; Masahiro Kato; Kensuke Otani; Takao Kamei; Daisuke Soma; Hideyo Miyato; Hiroharu Yamashita; Hirokazu Nagawa
Weekly intravenous and intraperitoneal paclitaxel combined with S-1 for malignant ascites due to advanced gastric cancer.
Oncology 2010;78(1):40-6.
2010: Hiroshi Kawasaki; Joji Kitayama; Hironori Ishigami; Akio Hidemura; Shoichi Kaisaki; Hirokazu Nagawa
Solitary splenic metastasis from early gastric cancer: report of a case.
Surgery today 2010;40(1):60-3.
2010: Hironori Yamaguchi; Masahiro Ishimaru; Hiroyuki Suzuki; Hiroharu Yamashita; Kazuhito Hatanaka; Toshimasa Uekusa; Hirokazu Nagawa
Isolated abdominal wound recurrence after lymph-node dissection for appendiceal adenocarcinoma.
American journal of surgery 2010;199(1):e7-9.
2010: H Ishigami; Joji Kitayama; Shoichi Kaisaki; Akio Hidemura; M Kato; K Otani; T Kamei; D Soma; Hideyo Miyato; Hiroharu Yamashita; Hirokazu Nagawa
Phase II study of weekly intravenous and intraperitoneal paclitaxel combined with S-1 for advanced gastric cancer with peritoneal metastasis.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2010;21(1):67-70.
2009: Takeshi Nishikawa; Toshiaki Watanabe; Eiji Sunami; Nelson H Tsuno; Joji Kitayama; Hirokazu Nagawa
Prognostic value of peritoneal cytology and the combination of peritoneal cytology and peritoneal dissemination in colorectal cancer.
Diseases of the colon and rectum 2009;52(12):2016-21.
2009: Toshiaki Watanabe; Takashi Kobunai; Toshiaki Tanaka; Soichiro Ishihara; K Matsuda; Hirokazu Nagawa
Gene expression signature and the prediction of lymph node metastasis in colorectal cancer by DNA microarray.
Diseases of the colon and rectum 2009;52(12):1941-8.
2009: Toshiaki Tanaka; Toshiaki Watanabe; Joji Kitayama; Takamitsu Kanazawa; Yoshihiro Kazama; Junichiro Tanaka; Shinsuke Kazama; Hirokazu Nagawa
Chromosome 18q deletion as a novel molecular predictor for colorectal cancer with simultaneous hepatic metastasis.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2009;18(4):219-25.
2009: Daisuke Soma; Joji Kitayama; Tomohiro Konno; Kazuhiko Ishihara; Jun Yamada; Takao Kamei; Hironori Ishigami; Shoichi Kaisaki; Hirokazu Nagawa
Intraperitoneal administration of paclitaxel solubilized with poly(2-methacryloxyethyl phosphorylcholine-co n-butyl methacrylate) for peritoneal dissemination of gastric cancer.
Cancer science 2009;100(10):1979-85.
2009: Hideyo Miyato; Joji Kitayama; Hiroharu Yamashita; Daisuke Souma; Masahiro Asakage; Jun Yamada; Hirokazu Nagawa
Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines.
The Journal of surgical research 2009;155(1):40-7.
2009: Toshio Takayama; Tetsushi Taguchi; Hiroyuki Koyama; Matomo Sakari; Wataru Kamimura; Tsuyoshi Takato; Tetsuro Miyata; Hirokazu Nagawa
The growth of a vascular network inside a collagen-citric acid derivative hydrogel in rats.
Biomaterials 2009;30(21):3580-7.
2009: Daisuke Soma; Joji Kitayama; Hironori Ishigami; Shoichi Kaisaki; Hirokazu Nagawa
Different tissue distribution of paclitaxel with intravenous and intraperitoneal administration.
The Journal of surgical research 2009;155(1):142-6.
2009: Takuhei Hashimoto; Hiroyuki Koyama; Toshio Miyata; Akihiro Hosaka; Yasuhiko Tabata; Tsuyoshi Takato; Hirokazu Nagawa
Selective and sustained delivery of basic fibroblast growth factor (bFGF) for treatment of peripheral arterial disease: results of a phase I trial.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2009;38(1):71-5.
2009: Hiroharu Yamashita; Joji Kitayama; Hirokazu Nagawa
Chromoendoscopy with indigo carmine dye added to acetic acid in the diagnosis of gastric neoplasia.
Gastrointestinal endoscopy 2009;69(7):1407-8.
2009: Hiroharu Yamashita; Joji Kitayama; Masataka Taguri; Hirokazu Nagawa
Effect of preoperative hyperfibrinogenemia on recurrence of colorectal cancer without a systemic inflammatory response.
World journal of surgery 2009;33(6):1298-305.
2009: Takao Kamei; Joji Kitayama; Hiroharu Yamashita; Hirokazu Nagawa
Intraoperative blood loss is a critical risk factor for peritoneal recurrence after curative resection of advanced gastric cancer.
World journal of surgery 2009;33(6):1240-6.
2009: Naoyuki Yoshikawa; Jun Yamada; Nelson H Tsuno; Yurai Okaji; Kazushige Kawai; Takeshi Tsuchiya; Satomi Yoneyama; Junichiro Tanaka; Yasutaka Shuno; Takeshi Nishikawa; Hirokazu Nagawa; Noriko Oshima; Koki Takahashi
Plaunotol and geranylgeraniol induce caspase-mediated apoptosis in colon cancer.
The Journal of surgical research 2009;153(2):246-53.
2009: Shinichiro Koketsu; Tomomi Watanabe; Manabu Minami; Joji Kitayama; Yutaka J Kawamura; Hirokazu Nagawa
Preoperative evaluation of enterovesical fistula using magnetic resonance imaging: case report.
Hepato-gastroenterology 2009;56(91-92):696-8.
2009: Toshio Takayama; Tetsuro Miyata; Hirokazu Nagawa
True abdominal aortic aneurysm in Marfan syndrome.
Journal of vascular surgery 2009;49(5):1162-5.
2009: Takeshi Nishikawa; Nelson H Tsuno; Takeshi Tsuchiya; Satomi Yoneyama; Jun Yamada; Yasutaka Shuno; Yurai Okaji; Junichiro Tanaka; Joji Kitayama; Koki Takahashi; Hirokazu Nagawa
Sulforaphane stimulates activation of proapoptotic protein bax leading to apoptosis of endothelial progenitor cells.
Annals of surgical oncology 2009;16(2):534-43.
2009: Toshiaki Watanabe; Takashi Kobunai; Etsuko Sakamoto; Yoko Yamamoto; Tsuyoshi Konishi; Atsushi Horiuchi; Ryu Shimada; Toshinori Oka; Hirokazu Nagawa
Gene expression signature for recurrence in stage III colorectal cancers.
Cancer 2009;115(2):283-92.
2009: Go Urabe; Kota Yamamoto; Tetsuro Miyata; Atsuko Onozuka; Hirokazu Nagawa
Skin Perfusion Pressure is a Useful Tool for Evaluating Outcome of Ischemic Foot Ulcers with Conservative Therapy.
Annals of vascular diseases 2009;2(1):21-6.
2009: Hironori Ishigami; Joji Kitayama; Kensuke Otani; Takao Kamei; Daisuke Soma; Hideyo Miyato; Hiroharu Yamashita; Akio Hidemura; Shoichi Kaisaki; Hirokazu Nagawa
Phase I pharmacokinetic study of weekly intravenous and intraperitoneal paclitaxel combined with S-1 for advanced gastric cancer.
Oncology 2009;76(5):311-4.
2009: Jun Suzuki; Shinsuke Kazama; Joji Kitayama; Hiroshi Uozaki; Tetsuro Miyata; Hirokazu Nagawa
Signet ring cell carcinoma of the appendix manifesting as colonic obstruction and ovarian tumors: report of a case.
Surgery today 2009;39(3):235-40.
2009: Joji Kitayama; Masafumi Tabuchi; Giichiro Tsurita; Makoto Ishikawa; Kensuke Otani; Hirokazu Nagawa
Adiposity and gastrointestinal malignancy.
Digestion 2009;79 Suppl 1():26-32.
2008: Jun Yamada; Joji Kitayama; Nelson H Tsuno; Hiroharu Yamashita; Hideyo Miyato; Daisuke Soma; Kensuke Otani; Takao Kamei; Hironori Ishigami; Akio Hidemura; Shoichi Kaisaki; Koki Takahashi; Hirokazu Nagawa
Intra-peritoneal administration of paclitaxel with non-animal stabilized hyaluronic acid as a vehicle--a new strategy against peritoneal dissemination of gastric cancer.
Cancer letters 2008;272(2):307-15.
2008: Wei Zhang; Wei Tang; Yoshinori Inagaki; Ming Qiu; Huan-Li Xu; Xun Li; Yasuhiko Sugawara; Hirokazu Nagawa; Munehiro Nakata; Norihiro Kokudo
Positive KL-6 mucin expression combined with decreased membranous beta-catenin expression indicates worse prognosis in colorectal carcinoma.
Oncology reports 2008;20(5):1013-9.
2008: Hiroshi Suzuki; Giichiro Tsurita; Masaaki Akahane; Soichiro Ishihara; Joji Kitayama; Hirokazu Nagawa
Resovist-enhanced MRI for preoperative assessment of colorectal hepatic metastases: a case of multiple bile duct hamartomas associated with colon cancer.
Case reports in gastroenterology 2008;2(3):509-16.
2008: Daisuke Soma; Joji Kitayama; Hiroharu Yamashita; Hideyo Miyato; Makoto Ishikawa; Hirokazu Nagawa
Leptin augments proliferation of breast cancer cells via transactivation of HER2.
The Journal of surgical research 2008;149(1):9-14.
2008: Toshio Takayama; Tetsuro Miyata; Motoaki Shirakawa; Hirokazu Nagawa
Isolated spontaneous dissection of the splanchnic arteries.
Journal of vascular surgery 2008;48(2):329-33.
2008: Junichiro Tanaka; Toshiaki Watanabe; Takamitsu Kanazawa; Tomohiro Tada; Yoshihiro Kazama; Toshiaki Tanaka; Hirokazu Nagawa
Silencing of secreted frizzled-related protein genes in MSI colorectal carcinogenesis.
Hepato-gastroenterology 2008;55(85):1265-8.
2008: Keiichi Nakagawa; Hideomi Yamashita; Naoki Nakamura; Hiroshi Igaki; Masao Tago; Yoshio Hosoi; Toshimitsu Momose; Kuni Ohtomo; Tetsuichiro Muto; Hirokazu Nagawa
Preoperative radiation response evaluated by 18-fluorodeoxyglucose positron emission tomography predicts survival in locally advanced rectal cancer.
Diseases of the colon and rectum 2008;51(7):1055-60.
2008: Kota Yamamoto; Hideo Kimura; T Murayama; Takeshi Kashima; Y Kikuchi; T Akiyama; H Kawano; Toshio Miyata; Hirokazu Nagawa
Chronic expanding hematoma in combination with a pseudoaneurysm: a case report.
International angiology : a journal of the International Union of Angiology 2008;27(3):266-8.
2008: Masafumi Tabuchi; Joji Kitayama; Hirokazu Nagawa
Hyperglycemia and hypertriglyceridemia may associate with the adenoma-carcinoma transition in colorectal epithelial cells.
Journal of gastroenterology and hepatology 2008;23(6):985-7.
2008: Takeshi Tsuchiya; Nelson H Tsuno; Masahiro Asakage; Jun Yamada; Satomi Yoneyama; Yurai Okaji; Shin Sasaki; Joji Kitayama; Takuya Osada; Koki Takahashi; Hirokazu Nagawa
Apoptosis induction by p38 MAPK inhibitor in human colon cancer cells.
Hepato-gastroenterology 2008;55(84):930-5.
2008: Yusuke Kazama; Toshiaki Watanabe; Takamitsu Kanazawa; Junichiro Tanaka; Toshiaki Tanaka; Hirokazu Nagawa
Poorly differentiated colorectal adenocarcinomas show higher rates of microsatellite instability and promoter methylation of p16 and hMLH1: a study matched for T classification and tumor location.
Journal of surgical oncology 2008;97(3):278-83.
2008: Shin Sasaki; Takashi Kobunai; Joji Kitayama; Hirokazu Nagawa
DNA methylation and sensitivity to antimetabolites in cancer cell lines.
Oncology reports 2008;19(2):407-12.
2008: Yurai Okaji; Nelson H Tsuno; Minoru Tanaka; Satomi Yoneyama; Mika Matsuhashi; Joji Kitayama; Shinsuke Saito; Yutaka Nagura; Takeshi Tsuchiya; Jun Yamada; Junichiro Tanaka; Naoyuki Yoshikawa; Takeshi Nishikawa; Yasutaka Shuno; Tomoki Todo; Nobuhito Saito; Koki Takahashi; Hirokazu Nagawa
Pilot study of anti-angiogenic vaccine using fixed whole endothelium in patients with progressive malignancy after failure of conventional therapy.
European journal of cancer (Oxford, England : 1990) 2008;44(3):383-90.
2008: Takayuki Matsumoto; Yasushi Iwao; Masahiro Igarashi; Kenji Watanabe; Kazuo Otsuka; Toshiaki Watanabe; Bunei Iizuka; Nobuyuki Hida; Miwa Sada; Toshimi Chiba; Shin-ei Kudo; Nobuhide Oshitani; Hirokazu Nagawa; Yoichi Ajioka; Toshifumi Hibi
Endoscopic and chromoendoscopic atlas featuring dysplastic lesions in surveillance colonoscopy for patients with long-standing ulcerative colitis.
Inflammatory bowel diseases 2008;14(2):259-64.
2008: Soichiro Ishihara; Toshiaki Watanabe; Hirokazu Nagawa
Intraoperative colonoscopy for stapled anastomosis in colorectal surgery.
Surgery today 2008;38(11):1063-5.
2008: Kensuke Otani; Joji Kitayama; Shoichi Kaisaki; Hironori Ishigami; Akio Hidemura; Mitsuhiro Fujishiro; Masao Omata; Hirokazu Nagawa
Early gastric cancer shows different associations with adipose tissue volume depending on histological type.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2008;11(2):86-95.
2008: Naoya Murakami; Keiichi Nakagawa; Hideomi Yamashita; Hirokazu Nagawa
Palliative radiation therapy for advanced gastrointestinal cancer.
Digestion 2008;77 Suppl 1():29-35.
2008: Shuangta Xu; Joji Kitayama; Hiroharu Yamashita; Daisuke Souma; Hirokazu Nagawa
Nuclear translocation of HER-4/c-erbB-4 is significantly correlated with prognosis of esophageal squamous cell carcinoma.
Journal of surgical oncology 2008;97(1):44-50.
2008: Satomi Yoneyama; Kazushige Kawai; Nelson H Tsuno; Yurai Okaji; Masahiro Asakage; Takeshi Tsuchiya; Jun Yamada; Eiji Sunami; Takuya Osada; Joji Kitayama; Koki Takahashi; Hirokazu Nagawa
Epigallocatechin gallate affects human dendritic cell differentiation and maturation.
The Journal of allergy and clinical immunology 2008;121(1):209-14.
2008: Toshiaki Tanaka; Toshiaki Watanabe; Yusuke Kazama; Junichiro Tanaka; Takamitsu Kanazawa; Shinsuke Kazama; Hirokazu Nagawa
Loss of Smad4 protein expression and 18qLOH as molecular markers indicating lymph node metastasis in colorectal cancer--a study matched for tumor depth and pathology.
Journal of surgical oncology 2008;97(1):69-73.
2007: Junichiro Tanaka; Toshiaki Watanabe; Takamitsu Kanazawa; Tomohiro Tada; Yusuke Kazama; Toshiaki Tanaka; Hirokazu Nagawa
Left-Sided microsatellite unstable colorectal cancers show less frequent methylation of hMLH1 and CpG island methylator phenotype than right-sided ones.
Journal of surgical oncology 2007;96(7):611-8.
2007: Satomi Yoneyama; Yurai Okaji; Nelson H Tsuno; Kazushige Kawai; Hiroharu Yamashita; Takeshi Tsuchiya; Jun Yamada; Eiji Sunami; Takuya Osada; Joji Kitayama; Koki Takahashi; Hirokazu Nagawa
A study of dendritic and endothelial cell interactions in colon cancer in a cell line and small mammal model.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2007;33(10):1191-8.
2007: Soichiro Ishihara; Joji Kitayama; Hirokazu Nagawa
Clinical challenges and images in GI. Amoebic appendicitis.
Gastroenterology 2007;133(5):1412, 1747.
2007: Kouhei Fukushima; Hisao Fujii; Takehira Yamamura; Akira Sugita; Shingo Kameoka; Hirokazu Nagawa; Kitaro Futami; Toshiaki Watanabe; Katsuyoshi Hatakeyama; Toshio Sawada; Kazuhiko Yoshioka; Masato Kusunoki; Fumio Konishi; Masahiko Watanabe; Ken-Ichi Takahashi; Hitoshi Ogawa; Yuji Funayama; Toshifumi Hibi; Iwao Sasaki
Pouchitis atlas for objective endoscopic diagnosis.
Journal of gastroenterology 2007;42(10):799-806.
2007: Tomomichi Kiyomatsu; Toshiaki Watanabe; Tetsuichiro Muto; Hirokazu Nagawa
The 4-portal technique decreases adverse effects in preoperative radiotherapy for advanced rectal cancer: comparison between the 2-portal and the 4-portal techniques.
American journal of surgery 2007;194(4):542-8.
2007: Kota Yamamoto; Toshio Miyata; Hirokazu Nagawa
Good correlation between cerebral oxygenation measured using near infrared spectroscopy and stump pressure during carotid clamping.
International angiology : a journal of the International Union of Angiology 2007;26(3):262-5.
2007: Hideo Kagaya; Joji Kitayama; Akio Hidemura; Shoichi Kaisaki; Hironori Ishigami; Junko Takei; Takamitsu Kanazawa; Hirokazu Nagawa
Metastatic esophageal tumor from cecal carcinoma.
Japanese journal of clinical oncology 2007;37(8):628-31.
2007: Jun Yamada; Kazushige Kawai; Nelson H Tsuno; Joji Kitayama; Takeshi Tsuchiya; Satomi Yoneyama; Masahiro Asakage; Yurai Okaji; Koki Takahashi; Hirokazu Nagawa
Plaunotol induces apoptosis of gastric cancer cells.
Planta medica 2007;73(10):1068-73.
2007: Yoshiyuki Takimoto; Shoichi Maeda; Brian Taylor Slingsby; Kenji Harada; Takashi Nagase; Hirokazu Nagawa; Ryozo Nagai; Ryozo Naga; Akira Akabayashi
A template for informed consent forms in medical examination and treatment: an intervention study.
Medical science monitor : international medical journal of experimental and clinical research 2007;13(8):PH15-8.
2007: Tetsu Kojima; Toshiahi Watanabe; Keisuke Hata; Hirokazu Nagawa
Basic fibroblast growth factor enema improves experimental colitis in rats.
Hepato-gastroenterology 2007;54(77):1373-7.
2007: Ken Mori; Joji Kitayama; Junken Aoki; Yasuhiro Kishi; Dai Shida; Hiroharu Yamashita; Hiroyuki Arai; Hirokazu Nagawa
Submucosal connective tissue-type mast cells contribute to the production of lysophosphatidic acid (LPA) in the gastrointestinal tract through the secretion of autotaxin (ATX)/lysophospholipase D (lysoPLD).
Virchows Archiv : an international journal of pathology 2007;451(1):47-56.
2007: Daisuke Akagi; M Oba; Hiroyuki Koyama; Nobuhiro Nishiyama; S Fukushima; Toshio Miyata; Hirokazu Nagawa; Kazunori Kataoka
Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation.
Gene therapy 2007;14(13):1029-38.
2007: Makoto Ishikawa; Joji Kitayama; Toshimasa Yamauchi; Takashi Kadowaki; Toshiyuki Maki; Hideyo Miyato; Hiroharu Yamashita; Hirokazu Nagawa
Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.
Cancer science 2007;98(7):1120-7.
2007: Hiroaki Nozawa; Toshiaki Watanabe; Hirokazu Nagawa
Phosphorylation of ribosomal p70 S6 kinase and rapamycin sensitivity in human colorectal cancer.
Cancer letters 2007;251(1):105-13.
2007: Joji Kitayama; Hironori Ishigami; Makoto Ishikawa; Hiroharu Yamashita; Daisuke Soma; Hideyo Miyato; Hirokazu Nagawa
Hyaluronic acid is a useful tool for intraoperative sentinel node detection in gastric cancer surgery.
Surgery 2007;141(6):815-20.
2007: Yusuke Kazama; Toshiaki Watanabe; Takamitsu Kanazawa; Junichiro Tanaka; Toshiaki Tanaka; Hirokazu Nagawa
Microsatellite instability in poorly differentiated adenocarcinomas of the colon and rectum: relationship to clinicopathological features.
Journal of clinical pathology 2007;60(6):701-4.
2007: Tsuyoshi Konishi; Toshiaki Watanabe; Junji Kishimoto; Kenjiro Kotake; Tetsuichiro Muto; Hirokazu Nagawa
Prognosis and risk factors of metastasis in colorectal carcinoids: results of a nationwide registry over 15 years.
Gut 2007;56(6):863-8.
2007: Keiichi Itatani; Tetsuro Miyata; Takashi Komiyama; Kunihiro Shigematsu; Hirokazu Nagawa
An ex-situ arterial reconstruction for the treatment of an infected suprarenal abdominal aortic aneurysm involving visceral vessels.
Annals of vascular surgery 2007;21(3):380-3.
2007: Daisuke Akagi; H Arita; Takashi Komiyama; Shigeyuki Ishii; Kunihiro Shigematsu; Hirokazu Nagawa; Toshio Miyata
Objective assessment of nerve injury after greater saphenous vein stripping.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2007;33(5):625-30.
2007: Kota Yamamoto; Toshio Miyata; Hirokazu Nagawa
The high prevalence of colorectal neoplasms in preoperative patients with abdominal aortic aneurysm or peripheral artery disease.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2007;33(4):397-400.
2007: Hiroharu Yamashita; Joji Kitayama; Makoto Ishikawa; Hirokazu Nagawa
Tissue factor expression is a clinical indicator of lymphatic metastasis and poor prognosis in gastric cancer with intestinal phenotype.
Journal of surgical oncology 2007;95(4):324-31.
2007: Takashi Kobunai; Akio Ooyama; Shin Sasaki; Konstanty Wierzba; Teiji Takechi; Masakazu Fukushima; Toshiaki Watanabe; Hirokazu Nagawa
Changes to the dihydropyrimidine dehydrogenase gene copy number influence the susceptibility of cancers to 5-FU-based drugs: Data mining of the NCI-DTP data sets and validation with human tumour xenografts.
European journal of cancer (Oxford, England : 1990) 2007;43(4):791-8.
2007: Kota Yamamoto; Toshio Miyata; Atsuko Onozuka; Hiroyuki Koyama; H Ohtsu; Hirokazu Nagawa
Plantar flexion as an alternative to treadmill exercise for evaluating patients with intermittent claudication.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2007;33(3):325-9.
2007: Tsuyoshi Konishi; Toshiaki Watanabe; Hirokazu Nagawa
Impaction of a rectal foreign body: what is the final approach before surgery?
Diseases of the colon and rectum 2007;50(2):262-3; author reply 263.
2007: Toshiaki Watanabe; Takashi Kobunai; Etsuko Toda; Takamitsu Kanazawa; Yoshihiro Kazama; Junichiro Tanaka; Toshiaki Tanaka; Yoko Yamamoto; Keisuke Hata; Tetsu Kojima; Tadashi Yokoyama; Tsuyoshi Konishi; Yoshihiro Okayama; Yoshikazu Sugimoto; Toshinori Oka; Shin Sasaki; Yohichi Ajioka; Tetsuichiro Muto; Hirokazu Nagawa
Gene expression signature and the prediction of ulcerative colitis-associated colorectal cancer by DNA microarray.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(2 Pt 1):415-20.
2007: Takuya Hashimoto; Joji Kitayama; Akio Hidemura; Hironori Ishigami; Shoichi Kaizaki; Noriyoshi Fukushima; Tetsuro Miyata; Hirokazu Nagawa
Ume (Japanese apricot)-induced small bowel obstruction with chronic radiation enteritis.
Case reports in gastroenterology 2007;1(1):184-9.
2007: Shinsuke Kazama; Toshiaki Watanabe; Takamitsu Kanazawa; Kenji Hatano; Hirokazu Nagawa
Vascular endothelial growth factor-C (VEGF-C) is a more specific risk factor for lymph node metastasis than VEGF-D in submucosal colorectal cancer.
Hepato-gastroenterology 2007;54(73):71-6.
2007: Yoshinori Inagaki; Wei Tang; Qian Guo; Norihiro Kokudo; Yasuhiko Sugawara; Hirona Karako; Toshiro Konishi; Munehiro Nakata; Hirokazu Nagawa; Makuuchi Masatoshi
Sialoglycoconjugate expression in primary colorectal cancer and metastatic lymph node tissues.
Hepato-gastroenterology 2007;54(73):53-7.
2007: Shoichi Kaisaki; Joji Kitayama; Hironori Ishigami; Hirokazu Nagawa
Solitary nodal recurrence in the dorsal area of the thoracic aorta after a curative resection of esophageal cancer: report of two cases.
Surgery today 2007;37(3):243-7.
2007: Tsuyoshi Konishi; Toshiaki Watanabe; Tomomichi Kiyomatsu; Hirokazu Nagawa
Perioperative radiation for rectal cancer and sexual dysfunction after TME: cause and effect?
Annals of surgery 2007;245(1):155.
2006: T Tanaka; Tomomi Watanabe; Yusuke Kazama; Junichiro Tanaka; Takamitsu Kanazawa; Shinsuke Kazama; Hirokazu Nagawa
Chromosome 18q deletion and Smad4 protein inactivation correlate with liver metastasis: A study matched for T- and N- classification.
British journal of cancer 2006;95(11):1562-7.
2006: Daisuke Akagi; H Oshiro; Kota Yamamoto; Hideo Kimura; K Taniwaka; Hiroshi Shigematsu; Hirokazu Nagawa; Toshio Miyata
Popliteal venous aneurysm with repeated episodes of pulmonary embolism. Case report and literature review.
International angiology : a journal of the International Union of Angiology 2006;25(4):427-32.
2006: Kota Yamamoto; Toshio Miyata; Toshimitsu Momose; Mikiko Nagayoshi; Daisuke Akagi; Akihiro Hosaka; Takuya Miyahara; Shigeyuki Ishii; Hideo Kimura; Juno Deguchi; Kunihiro Shigematsu; Hiroshi Shigematsu; Hirokazu Nagawa
Reduced vascular reserve measured by stressed single photon emission computed tomography carries a high risk for stroke in patients with carotid stenosis.
International angiology : a journal of the International Union of Angiology 2006;25(4):385-8.
2006: Takeshi Tsuchiya; Toshiaki Watanabe; Tsuyoshi Konishi; Hirokazu Nagawa
Toxic megacolon associated with Crohn's disease.
Gastrointestinal endoscopy 2006;64(6):1012-3; discussion 1013.
2006: Ikuo Nagashima; Tadahiro Takada; Hirokazu Nagawa; Tetsuichiro Muto; Kota Okinaga
Proposal of a new and simple staging system of colorectal liver metastasis.
World journal of gastroenterology : WJG 2006;12(43):6961-5.
2006: Makoto Motoyoshi; Masanori Sugiyama; Yutaka Atomi; Wataru Kimura; Hirokazu Nagawa
Effect of a selective thromboxane A2 synthetase inhibitor on the systemic changes induced by circulating pancreatic phospholipase A2.
Journal of gastroenterology 2006;41(11):1094-8.
2006: Tsuyoshi Konishi; Toshiaki Watanabe; Junji Kishimoto; Hirokazu Nagawa
Elective colon and rectal surgery differ in risk factors for wound infection: results of prospective surveillance.
Annals of surgery 2006;244(5):758-63.
2006: Ikuo Nagashima; Tadahiro Takada; Miki Adachi; Hirokazu Nagawa; Tetsuichiro Muto; Kota Okinaga
Proposal of criteria to select candidates with colorectal liver metastases for hepatic resection: comparison of our scoring system to the positive number of risk factors.
World journal of gastroenterology : WJG 2006;12(39):6305-9.
2006: Toshiaki Watanabe; Takashi Kobunai; Etsuko Toda; Yoko Yamamoto; Takamitsu Kanazawa; Yoshihiro Kazama; Junichiro Tanaka; Toshiaki Tanaka; Tsuyosi Konishi; Yoshihiro Okayama; Yoshikazu Sugimoto; Toshinori Oka; Shin Sasaki; Tetsuichiro Muto; Hirokazu Nagawa
Distal colorectal cancers with microsatellite instability (MSI) display distinct gene expression profiles that are different from proximal MSI cancers.
Cancer research 2006;66(20):9804-8.
2006: Shin Sasaki; Toshiaki Watanabe; Takashi Kobunai; Hirokazu Nagawa
Effect of cystathionine beta-synthase variant 844ins68bp and methylenetetrahydrofolate reductase A1298C polymorphisms in xenografts on 5-FU efficacy and doubling time.
Cancer letters 2006;241(2):256-62.
2006: Makoto Ishikawa; Joji Kitayama; Hirokazu Nagawa
Expression pattern of leptin and leptin receptor (OB-R) in human gastric cancer.
World journal of gastroenterology : WJG 2006;12(34):5517-22.
2006: Takuya Miyahara; Tetsuro Miyata; Kunihiro Shigematsu; Juno Deguchi; Hideo Kimura; Shigeyuki Ishii; Hirokazu Nagawa
Clinical outcome and complications of temporary inferior vena cava filter placement.
Journal of vascular surgery 2006;44(3):620-4.
2006: Joji Kitayama; Tetsuro Morota; Shoichi Kaisaki; Hiroshi Nakayama; Hironori Ishigami; Hiroharu Yamashita; Makoto Ishikawa; Ko Shibata; Shinichi Takamoto; Hirokazu Nagawa
Complete coverage of in situ aortograft by total omental pedicle flap as the most reliable treatment of aortoesophageal fistula.
American journal of surgery 2006;192(1):130-4.
2006: T Watanabe; Tomomichi Kiyomatsu; T Kanazawa; Yusuke Kazama; T Kojima; J Tanaka; T Tanaka; Hirokazu Nagawa
Weekly oxaliplatin and preoperative radiotherapy as a new neoadjuvant therapy for locally-advanced rectal cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(7):1173; author reply 1173-4.
2006: Toshiaki Watanabe; Takamitsu Kanazawa; Yoshihiro Kazama; Junichiro Tanaka; Toshiaki Tanaka; Soichiro Ishihara; Hirokazu Nagawa; Piero Benatti; Maurizio Ponz de Leon; Roberta Gafá; Roberta Gafà; Daniela Barana; Cristina Oliani
Adjuvant chemotherapy in colorectal cancer patients with microsatellite instability.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(12):3866-7; author reply 3867.
2006: Daisuke Akagi; Shigeyuki Ishii; Takeshi Kitagawa; Hirokazu Nagawa; Tetsuro Miyata
Popliteal arterial aneurysm associated with Klippel-Trénaunay syndrome: case report and literature review.
Journal of vascular surgery 2006;43(6):1287-9.
2006: Tetsu Kojima; Toshiaki Watanabe; Keisuke Hata; Masaru Shinozaki; Tadashi Yokoyama; Hirokazu Nagawa
Cytomegalovirus infection in ulcerative colitis.
Scandinavian journal of gastroenterology 2006;41(6):706-11.
2006: Masaru Shinozaki; Toshiaki Watanabe; Hajime Sato; Hirokazu Nagawa
Chronic colitis promotes tumor development.
Oncology reports 2006;15(6):1485-90.
2006: Masahiro Asakage; Nelson H Tsuno; Joji Kitayama; Kazushige Kawai; Yurai Okaji; Kentaro Yazawa; Shoichi Kaisaki; Takuya Osada; Toshiaki Watanabe; Koki Takahashi; Hirokazu Nagawa
Early-outgrowth of endothelial progenitor cells can function as antigen-presenting cells.
Cancer immunology, immunotherapy : CII 2006;55(6):708-16.
2006: Tsuyoshi Konishi; Sei Sasaki; Tomomi Watanabe; Joji Kitayama; Hirokazu Nagawa
Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-kappaB and upregulation of BCL-2 and BCL-XL.
Oncogene 2006;25(22):3160-9.
2006: Tsuyoshi Konishi; Toshiaki Watanabe; Keita Morikane; Kazuhiko Fukatsu; Joji Kitayama; Naoyuki Umetani; Junji Kishimoto; Hirokazu Nagawa
Prospective surveillance effectively reduced rates of surgical site infection associated with elective colorectal surgery at a university hospital in Japan.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2006;27(5):526-8.
2006: Shin Sasaki; Toshiaki Watanabe; Takashi Kobunai; Tsuyoshi Konishi; Hideki Nagase; Yoshikazu Sugimoto; Toshinori Oka; Hirokazu Nagawa
hRFI overexpressed in HCT116 cells modulates Bcl-2 family proteins when treated with 5-fluorouracil.
Oncology reports 2006;15(5):1293-8.
2006: Yurai Okaji; Nelson H Tsuno; Shinsuke Saito; Satomi Yoneyama; M Tanaka; Hirokazu Nagawa; Koki Takahashi
Vaccines targeting tumour angiogenesis--a novel strategy for cancer immunotherapy.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2006;32(4):363-70.
2006: Ken Mori; Joji Kitayama; Dai Shida; Hiroharu Yamashita; Toshiaki Watanabe; Hirokazu Nagawa
Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.
The Journal of surgical research 2006;132(1):56-61.
2006: Akihiro Hosaka; Tetsuro Miyata; Hiroshi Shigematsu; Juno Deguchi; Hideo Kimura; Hirokazu Nagawa; Osamu Sato; Takehiko Sakimoto; Tomoyuki Mochizuki
Spontaneous mesenteric hemorrhage associated with Ehlers-Danlos syndrome.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2006;10(4):583-5.
2006: Toshiaki Watanabe; Yasuhiro Komuro; Tomomichi Kiyomatsu; Takamitsu Kanazawa; Yusuke Kazama; Junichiro Tanaka; Toshiaki Tanaka; Yoko Yamamoto; Masatoshi Shirane; Tetsuichiro Muto; Hirokazu Nagawa
Prediction of sensitivity of rectal cancer cells in response to preoperative radiotherapy by DNA microarray analysis of gene expression profiles.
Cancer research 2006;66(7):3370-4.
2006: Tsuyoshi Konishi; Toshiaki Watanabe; Hirokazu Nagawa
Formalin application in the treatment of chronic radiation-induced hemorrhagic proctitis induces acute deterioration of mucosal blood flow.
Diseases of the colon and rectum 2006;49(4):530-1; author reply 531-2.
2006: Hironori Yamaguchi; Makoto Ishikawa; Kazuhito Hatanaka; Toshimasa Uekusa; Masahiro Ishimaru; Hirokazu Nagawa
Occult breast cancer presenting as axillary metastases.
Breast (Edinburgh, Scotland) 2006;15(2):259-62.
2006: Tatsuya Ohnishi; Toshiaki Watanabe; Hiroaki Nozawa; Hirokazu Nagawa
Telomerase subunit immunoreactivity and recurrence in colorectal cancer.
Hepato-gastroenterology 2006;53(68):188-91.
2006: Makoto Motoyoshi; Shintaro Nomura; Toshiyuki Watanabe; Kennoki Kyo; Haruko Watanabe; Seiji Negishi; Hirokazu Nagawa
Biliary cystadenocarcinoma presenting as recurrent cholangitis.
Surgery 2006;139(3):448-50.
2006: Toshiaki Watanabe; Takamitsu Kanazawa; Yoshihiro Kazama; Junichiro Tanaka; Toshiaki Tanaka; Soichiro Ishihara; Hirokazu Nagawa
SMAD4 levels and allelic imbalance in 18q21 in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(5):1654; author reply 1654-5.
2006: Yusuke Kazama; Toshiaki Watanabe; Takamitsu Kanazawa; Shinsuke Kazama; Tomohiro Tada; Junichiro Tanaka; Hirokazu Nagawa
Mucinous colorectal cancers with chromosomal instability: a biologically distinct and aggressive subtype.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2006;15(1):30-4.
2006: Kota Yamamoto; Toshio Miyata; Mikiko Nagayoshi; Daisuke Akagi; Akihiro Hosaka; Takuya Miyahara; Shigeyuki Ishii; Kunihiro Shigematsu; Hiroshi Shigematsu; Hirokazu Nagawa
Carotid endarterectomy may reduce the high stroke rate for patients with the disease of abdominal aorta and peripheral arteries.
International angiology : a journal of the International Union of Angiology 2006;25(1):35-9.
2006: Takuya Miyahara; Hiroyuki Koyama; Tetsuro Miyata; Hiroshi Shigematsu; Jun-Ichiro Inoue; Tsuyoshi Takato; Hirokazu Nagawa
Inflammatory responses involving tumor necrosis factor receptor-associated factor 6 contribute to in-stent lesion formation in a stent implantation model of rabbit carotid artery.
Journal of vascular surgery 2006;43(3):592-600.
2006: Tsuyoshi Konishi; Toshiaki Watanabe; Junji Kishimoto; Hirokazu Nagawa
Risk factors for anastomotic leakage after surgery for colorectal cancer: results of prospective surveillance.
Journal of the American College of Surgeons 2006;202(3):439-44.
2006: Yurai Okaji; Nelson H Tsuno; Joji Kitayama; Daisuke Sakurai; Naoyuki Tsuchiya; Shinsuke Saito; Kenji Takegami; Takeshi Tsuchiya; Kazushige Kawai; Kentaro Yazawa; Masahiro Asakage; Satomi Yoneyama; Jun Yamada; Katsushi Tokunaga; Koki Takahashi; Hirokazu Nagawa
Effects of down-regulating the Id genes in human colorectal cancer cells on early steps of haematogenous metastasis.
European journal of cancer (Oxford, England : 1990) 2006;42(5):668-73.
2006: Masafumi Tabuchi; Joji Kitayama; Hirokazu Nagawa
Hypertriglyceridemia is positively correlated with the development of colorectal tubular adenoma in Japanese men.
World journal of gastroenterology : WJG 2006;12(8):1261-4.
2006: Tsuyoshi Konishi; Toshiaki Watanabe; Tetsuichiro Muto; Kenjiro Kotake; Hirokazu Nagawa
Difference in incidence of colorectal cancer between men and women in Asia.
The lancet oncology 2006;7(2):104-5.
2006: Shinsuke Kazama; Tomomi Watanabe; Y Ajioka; Takamitsu Kanazawa; Hirokazu Nagawa
Tumour budding at the deepest invasive margin correlates with lymph node metastasis in submucosal colorectal cancer detected by anticytokeratin antibody CAM5.2.
British journal of cancer 2006;94(2):293-8.
2006: Qian Guo; Wei Tang; Yoshinori Inagaki; Yutaka Midorikawa; Norihiro Kokudo; Yasuhiko Sugawara; Munehiro Nakata; Toshiro Konishi; Hirokazu Nagawa; Makuuchi Masatoshi
Clinical significance of subcellular localization of KL-6 mucin in primary colorectal adenocarcinoma and metastatic tissues.
World journal of gastroenterology : WJG 2006;12(1):54-9.
2006: Akihiro Sako; Joji Kitayama; Makoto Ishikawa; Hiroharu Yamashita; Hirokazu Nagawa
Impact of immunohistochemically identified lymphatic invasion on nodal metastasis in early gastric cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2006;9(4):295-302.
2006: Toshiaki Watanabe; Eiji Sunami; Keisuke Hata; Hirokazu Nagawa
One-stage completely laparoscopic restorative proctocolectomy for ulcerative colitis complicated with sigmoid colon cancer--a case report.
Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy 2006;15(4):253-6.
2006: Masahiro Asakage; Nelson H Tsuno; Joji Kitayama; Takeshi Tsuchiya; Satomi Yoneyama; Jun Yamada; Yurai Okaji; Shoichi Kaisaki; Takuya Osada; Koki Takahashi; Hirokazu Nagawa
Sulforaphane induces inhibition of human umbilical vein endothelial cells proliferation by apoptosis.
Angiogenesis 2006;9(2):83-91.
2006: Hiroharu Yamashita; Joji Kitayama; Nobuko Kanno; Yutaka Yatomi; Hirokazu Nagawa
Hyperfibrinogenemia is associated with lymphatic as well as hematogenous metastasis and worse clinical outcome in T2 gastric cancer.
BMC cancer 2006;6():147.
2006: Hiroharu Yamashita; Masahiro Ishimaru; Hironori Yamaguchi; Haruo Yamauchi; Arishige Sugiura; Joji Kitayama; Hirokazu Nagawa
Massive postoperative polyuria following total gastrectomy for gastric cancer.
Journal of anesthesia 2006;20(1):36-9.
2006: Toshiaki Watanabe; Takamitsu Kanazawa; Yoshihiro Kazama; Junichiro Tanaka; Toshiaki Tanaka; Hirokazu Nagawa
Microsatellite instability in adenoma as a possible marker to identify HNPCC patients.
The American journal of gastroenterology 2006;101(1):204.
2006: Makoto Ishikawa; Joji Kitayama; Shoichi Kaisaki; Hiroyuki Okamoto; Tetsuro Miyata; Masaaki Akahane; Hirokazu Nagawa
Image of the month: left gastric aneurysm.
Gastroenterology 2006;130(1):7, 288.
2006: Tsuyoshi Konishi; Toshiaki Watanabe; Hirokazu Nagawa
Pelvic drainage should be a routine for TME with or without radiation.
Annals of surgery 2006;243(1):141-2; author reply 142.
2006: Hiroharu Yamashita; Joji Kitayama; Dai Shida; Makoto Ishikawa; Kotaro Hama; Junken Aoki; Hiroyuki Arai; Hirokazu Nagawa
Differential expression of lysophosphatidic acid receptor-2 in intestinal and diffuse type gastric cancer.
Journal of surgical oncology 2006;93(1):30-5.
2006: Hiroharu Yamashita; Joji Kitayama; Dai Shida; Hironori Yamaguchi; Ken Mori; Makoto Osada; Shinya Aoki; Yutaka Yatomi; Yoh Takuwa; Hirokazu Nagawa
Sphingosine 1-phosphate receptor expression profile in human gastric cancer cells: differential regulation on the migration and proliferation.
The Journal of surgical research 2006;130(1):80-7.
2006: Akihiro Sako; Joji Kitayama; Dai Shida; Rika Suzuki; Teruyuki Sakai; Hideo Ohta; Hirokazu Nagawa
Lysophosphatidic acid (LPA)-induced vascular endothelial growth factor (VEGF) by mesothelial cells and quantification of host-derived VEGF in malignant ascites.
The Journal of surgical research 2006;130(1):94-101.
2005: Toshiaki Watanabe; Takamitsu Kanazawa; Yoshihiro Kazama; Junichiro Tanaka; Toshiaki Tanaka; Soichiro Ishihara; Hirokazu Nagawa
TP53 mutation and microsatellite instability status for the prediction of survival in adjuvant-treated colon cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(35):9031-2; author reply 9032-3.
2005: Yusuke Kazama; Toshiaki Watanabe; Masaaki Akahane; Naoki Yoshioka; Kuni Ohtomo; Hirokazu Nagawa
Crohn's disease with life-threatening hemorrhage from terminal ileum: successful control by superselective arterial embolization.
Journal of gastroenterology 2005;40(12):1155-7.
2005: Takuya Miyahara; Toshio Miyata; Kunihiro Shigematsu; Hiroshi Shigematsu; Hiroyuki Koyama; Hiroyuki Okamoto; T Nakazawa; Hirokazu Nagawa
Persistent sciatic artery in a patient with extracranial internal carotid artery aneurysm and infrarenal abdominal aortic aneurysm. A case report.
International angiology : a journal of the International Union of Angiology 2005;24(4):391-4.
2005: Takuya Miyahara; Toshio Miyata; Hiroshi Shigematsu; Kunihiro Shigematsu; Hiroyuki Okamoto; T Nakazawa; Hirokazu Nagawa
Long-term results of combined iliac endovascular intervention and infrainguinal surgical revascularization for treatment of multilevel arterial occlusive disease.
International angiology : a journal of the International Union of Angiology 2005;24(4):340-8.
2005: T Saito; Y Hosoi; Atsuko Onozuka; Takashi Komiyama; Toshio Miyata; Hiroshi Shigematsu; Hirokazu Nagawa
Impaired ambulatory venous function in lymphedema assessed by near-infrared spectroscopy.
International angiology : a journal of the International Union of Angiology 2005;24(4):336-9.
2005: Peng Yu; Takuya Hatakeyama; Haruo Aramoto; Tetsuro Miyata; Hiroshi Shigematsu; Hirokazu Nagawa; Robert W Hobson; Walter N Durán
Mitogen-activated protein kinases regulate platelet-activating factor-induced hyperpermeability.
Microcirculation (New York, N.Y. : 1994) 2005;12(8):637-43.
2005: Takeshi Tsuchiya; Yurai Okaji; Nelson H Tsuno; Daisuke Sakurai; Naoyuki Tsuchiya; Kazushige Kawai; Kentaro Yazawa; Masahiro Asakage; Jun Yamada; Satomi Yoneyama; Joji Kitayama; Takuya Osada; Toshiaki Watanabe; Katsushi Tokunaga; Koki Takahashi; Hirokazu Nagawa
Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer.
Cancer science 2005;96(11):784-90.
2005: Keiichi Kawai; Toshiaki Watanabe; Hiroyuki Nakayama; Ic Roberts-Thomson; Hirokazu Nagawa
Images of interest. Gastrointestinal: small bowel inflammation and ulcerative colitis.
Journal of gastroenterology and hepatology 2005;20(11):1791.
2005: Makoto Ishikawa; Joji Kitayama; Shoichi Kaizaki; Hiroshi Nakayama; Hironori Ishigami; Shin Fujii; Hiroyuki Suzuki; Tomomi Inoue; Akihiro Sako; Masahiro Asakage; Hiroharu Yamashita; Kenji Hatono; Hirokazu Nagawa
Prospective randomized trial comparing Billroth I and Roux-en-Y procedures after distal gastrectomy for gastric carcinoma.
World journal of surgery 2005;29(11):1415-20; discussion 1421.
2005: Akihiro Hosaka; Tetsuro Miyata; Toshimitsu Momose; Tatsu Nakazawa; Hiroshi Shigematsu; Hirokazu Nagawa
Evaluation of cerebral hypoperfusion by nuclear medicine imaging in a patient with Takayasu's arteritis.
Annals of vascular surgery 2005;19(6):917-20.
2005: Dai Shida; Joji Kitayama; Ken Mori; Toshiaki Watanabe; Hirokazu Nagawa
Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells.
Cancer research 2005;65(20):9159-63.
2005: Masahiro Asakage; Nelson H Tsuno; Joji Kitayama; Jun Yamada; Takeshi Tsuchiya; Satomi Yoneyama; Koki Takahashi; Hirokazu Nagawa
[The effect of cimetidine mainly increases CD4+ cells of peripheral blood T lymphocytes].
Gan to kagaku ryoho. Cancer & chemotherapy 2005;32(11):1576-7.
2005: Hanako Ohmatsu; Hidehisa Saeki; Hideki Fujita; Keiko Toyoma; Makoto Sugaya; Akihiko Asahina; Shigeo Masuda; Hisamaru Hirai; Toshiaki Watanabe; Hirokazu Nagawa; Kunihiko Tamaki
Mycosis fungoides associated with intestinal mucosa-associated lymphoid tissue lymphoma.
International journal of dermatology 2005;44(10):878-80.
2005: Hiroharu Yamashita; Joji Kitayama; Hirokazu Nagawa
Hyperfibrinogenemia is a useful predictor for lymphatic metastasis in human gastric cancer.
Japanese journal of clinical oncology 2005;35(10):595-600.
2005: Tadahiko Masaki; Hiroyoshi Matsuoka; Masanori Sugiyama; Nobutsugu Abe; Atsuhiko Sakamoto; Toshiaki Watanabe; Hirokazu Nagawa; Yutaka Atomi
Tumor budding and evidence-based treatment of T2 rectal carcinomas.
Journal of surgical oncology 2005;92(1):59-63.
2005: Kenji Takegami; Yukio Kaneko; Toshiaki Watanabe; Shunsuke Watanabe; Toshiyuki Maruyama; Yoichiro Matsumoto; Hirokazu Nagawa
Heating and coagulation volume obtained with high-intensity focused ultrasound therapy: comparison of perflutren protein-type A microspheres and MRX-133 in rabbits.
Radiology 2005;237(1):132-6.
2005: Dai Shida; Joji Kitayama; Hironori Yamaguchi; Hiroharu Yamashita; Ken Mori; Toshiaki Watanabe; Hirokazu Nagawa
Lysophosphatidic acid transactivates both c-Met and epidermal growth factor receptor, and induces cyclooxygenase-2 expression in human colon cancer LoVo cells.
World journal of gastroenterology : WJG 2005;11(36):5638-43.
2005: Sei Sasaki; Tomomi Watanabe; Takashi Kobunai; Tsuyoshi Konishi; Joji Kitayama; Hirokazu Nagawa
High hRFI expression correlates with resistance to fluoropyrimidines in human colon cancer cell lines and in xenografts.
Journal of experimental & clinical cancer research : CR 2005;24(3):397-403.
2005: Hirokazu Tsuno; Yurai Okaji; Minoru Tanaka; Hirokazu Nagawa; Koki Takahashi
[Development of a novel anti-cancer therapy based on targeting of tumor microvessel endothelial cells].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 9():527-33.
2005: Makoto Ishikawa; Joji Kitayama; Shoichi Kaizaki; Akihiro Sako; Kazunari Nakao; Masashi Sugawara; Hirokazu Nagawa
Diagnosis of nasopharyngeal carcinoma metastatic to mediastinal lymph nodes by endoscopic ultrasonography-guided fine-needle aspiration biopsy.
Acta oto-laryngologica 2005;125(9):1014-7.
2005: Tsuyoshi Konishi; Toshiaki Watanabe; Yoshiki Takei; Tetsu Kojima; Hirokazu Nagawa
Confined progression of cap polyposis along the anastomotic line, implicating the role of inflammatory responses in the pathogenesis.
Gastrointestinal endoscopy 2005;62(3):446-7; discussion 447.
2005: Akihiro Hosaka; Tetsuro Miyata; Haruo Aramoto; Hiroshi Shigematsu; Tatsu Nakazawa; Hiroyuki Okamoto; Kunihiro Shigematsu; Hirokazu Nagawa
Clinical implication of plasma level of soluble fibrin monomer-fibrinogen complex in patients with abdominal aortic aneurysm.
Journal of vascular surgery 2005;42(2):200-5.
2005: Tsuyoshi Konishi; Shin Sasaki; Toshiaki Watanabe; Joji Kitayama; Hirokazu Nagawa
Exogenous expression of hRFI induces multidrug resistance through escape from apoptosis in colorectal cancer cells.
Anticancer research 2005;25(4):2737-41.
2005: Akihiro Hosaka; Tetsuro Miyata; Hiroshi Shigematsu; Kunihiro Shigematsu; Hiroyuki Okamoto; Shigeyuki Ishii; Takuya Miyahara; Kota Yamamoto; Daisuke Akagi; Mikiko Nagayoshi; Hirokazu Nagawa
Long-term outcome after surgical treatment of arterial lesions in Behçet disease.
Journal of vascular surgery 2005;42(1):116-21.
2005: Yasuhiro Komuro; Toshiaki Watanabe; Yoshio Hosoi; Yoshihisa Matsumoto; Keiichi Nakagawa; Norio Suzuki; Hirokazu Nagawa
Prognostic significance of Ku70 protein expression in patients with advanced colorectal cancer.
Hepato-gastroenterology 2005;52(64):995-8.
2005: Yasuhiro Komuro; Toshiaki Watanabe; Giichiro Tsurita; Tetsuichiro Muto; Hirokazu Nagawa
Expression pattern of telomerase reverse transcriptase in rectal carcinoma predicts tumor radiosensitivity, local recurrence and disease-free survival.
Hepato-gastroenterology 2005;52(64):985-9.
2005: Kazushige Kawai; Nelson H Tsuno; Mika Matsuhashi; Joji Kitayama; Takuya Osada; Jun Yamada; Takeshi Tsuchiya; Satomi Yoneyama; Toshiaki Watanabe; Koki Takahashi; Hirokazu Nagawa
CD11b-mediated migratory property of peripheral blood B cells.
The Journal of allergy and clinical immunology 2005;116(1):192-7.
2005: Yukio Kaneko; Toshiyuki Maruyama; Kenji Takegami; Toshiaki Watanabe; Hiroshi Mitsui; Kazuyuki Hanajiri; Hirokazu Nagawa; Yoichiro Matsumoto
Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.
European radiology 2005;15(7):1415-20.
2005: Hironori Yamaguchi; Hiroharu Yamashita; Haruo Yamauchi; Takashi Suzuki; Masahiro Ishimaru; Hirokazu Nagawa
Intestinal perforation caused by stagnated press-through packages.
Surgery 2005;137(6):661-2.
2005: Yusuke Kazama; Toshiaki Watanabe; Takamitsu Kanazawa; Tomohiro Tada; Junichiro Tanaka; Hirokazu Nagawa
Mucinous carcinomas of the colon and rectum show higher rates of microsatellite instability and lower rates of chromosomal instability: a study matched for T classification and tumor location.
Cancer 2005;103(10):2023-9.
2005: Yasuhiro Komuro; Toshiaki Watanabe; Giichiro Tsurita; Tetsuichiro Muto; Hirokazu Nagawa
Evaluating the combination of molecular prognostic factors in tumor radiosensitivity in rectal cancer.
Hepato-gastroenterology 2005;52(63):666-71.
2005: Masahiro Asakage; Joji Kitayama; Nelson H Tsuno; Yasuhiro Komuro; Shoichi Kaisaki; Nobukazu Hori; Hirokazu Nagawa; Nelson H Tsuno; Nobukazu Hori; Koki Takahashi
Primary malignant melanoma of the esophagus treated by esophagectomy and adjuvant dendritic-cell therapy.
Journal of gastroenterology 2005;40(5):545-6.
2005: Tsuyoshi Konishi; Shin Sasaki; Toshiaki Watanabe; Joji Kitayama; Hirokazu Nagawa
Overexpression of hRFI (human ring finger homologous to inhibitor of apoptosis protein type) inhibits death receptor-mediated apoptosis in colorectal cancer cells.
Molecular cancer therapeutics 2005;4(5):743-50.
2005: Toshiaki Watanabe; Hirokazu Nagawa
[Epidemiology of ulcerative colitis--comparison between Japan and western countries].
Nihon rinsho. Japanese journal of clinical medicine 2005;63(5):750-6.
2005: Makoto Ishikawa; Joji Kitayama; Shin Fujii; Hironori Ishigami; Shoichi Kaizaki; Hirokazu Nagawa
Recurrent intramucosal gastric carcinoma with extensive invasion to duodenal mucosa after endoscopic mucosal resection: a case report.
The American surgeon 2005;71(4):366-8.
2005: Hirokatsu Kinoshita; Akio Yanagisawa; Toshiaki Watanabe; Hirokazu Nagawa; Masatoshi Oya; Yo Kato; Tetsuichiro Muto
Increase in the frequency of K-ras codon 12 point mutation in colorectal carcinoma in elderly males in Japan: the 1990s compared with the 1960s.
Cancer science 2005;96(4):218-20.
2005: Kazushige Kawai; Nelson H Tsuno; Joji Kitayama; Yurai Okaji; Kentaro Yazawa; Masahiro Asakage; Hiroharu Yamashita; Toshiaki Watanabe; Koki Takahashi; Hirokazu Nagawa
Anti-angiogenic properties of plaunotol.
Anti-cancer drugs 2005;16(4):401-7.
2005: Kenji Takegami; Yukio Kaneko; Toshiaki Watanabe; Toshiyuki Maruyama; Yoichiro Matsumoto; Hirokazu Nagawa
Erythrocytes, as well as microbubble contrast agents, are important factors in improving thermal and therapeutic effects of high-intensity focused ultrasound.
Ultrasound in medicine & biology 2005;31(3):385-90.
2005: Dai Shida; Joji Kitayama; Hironori Yamaguchi; Hiroharu Yamashita; Ken Mori; Toshiaki Watanabe; Hirokazu Nagawa
Lysophospholipids transactivate HER2/neu (erbB-2) in human gastric cancer cells.
Biochemical and biophysical research communications 2005;327(3):907-14.
2005: Kentaro Yazawa; Nelson H Tsuno; Joji Kitayama; Kazushige Kawai; Yurai Okaji; Masahiro Asakage; Eiji Sunami; Shoichi Kaisaki; Nobukazu Hori; Toshiaki Watanabe; Koki Takahashi; Hirokazu Nagawa
Selective inhibition of cyclooxygenase (COX)-2 inhibits endothelial cell proliferation by induction of cell cycle arrest.
International journal of cancer. Journal international du cancer 2005;113(4):541-8.
2005: Kentaro Yazawa; Nelson H Tsuno; Joji Kitayama; Kazushige Kawai; Yurai Okaji; Masahiro Asakage; Eiji Sunami; Shoichi Kaisaki; Nobukazu Hori; Toshiaki Watanabe; Koki Takahashi; Hirokazu Nagawa
Selective inhibition of cyclooxygenase-2 inhibits colon cancer cell adhesion to extracellular matrix by decreased expression of beta1 integrin.
Cancer science 2005;96(2):93-9.
2005: Akihiro Sako; Joji Kitayama; Tomomi Inoue; Shoichi Kaizaki; Hirokazu Nagawa; Hiroyuki Suzuki
Black oesophagus--cause?
Gut 2005;54(2):192, 227.
2005: Makoto Ishikawa; Joji Kitayama; Shinsuke Kazama; Takeyuki Hiramatsu; Kenji Hatano; Hirokazu Nagawa
Plasma adiponectin and gastric cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):466-72.
2005: Makoto Ishikawa; Joji Kitayama; Kimitoshi Kohno; Hirokazu Nagawa
The expression pattern of UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetyl-galactosaminyl transferase-3 in squamous cell carcinoma of the esophagus.
Pathobiology : journal of immunopathology, molecular and cellular biology 2005;72(3):139-45.
2005: Lian-Wen Yuan; Wei Tang; Norihiro Kokudo; Yasuji Seyama; Ya-Zhou Shi; Hirona Karako; Bin Zhao; Yasuhiko Sugawara; Hirokazu Nagawa; Makuuchi Masatoshi
Disruption of pRb-p16INK4 pathway: a common event in ampullary carcinogenesis.
Hepato-gastroenterology 2005;52(61):55-9.
2005: Ikuo Nagashima; Tadahiro Takada; Kota Okinaga; Hirokazu Nagawa
A scoring system for the assessment of the risk of mortality after partial hepatectomy in patients with chronic liver dysfunction.
Journal of hepato-biliary-pancreatic surgery 2005;12(1):44-8.
2005: Tsuyoshi Konishi; Toshiaki Watanabe; Joji Kitayama; Junji Shibahara; Hirokazu Nagawa
Endoscopic and histopathologic findings after formalin application for hemorrhage caused by chronic radiation-induced proctitis.
Gastrointestinal endoscopy 2005;61(1):161-4.
2005: Kazushige Kawai; Nelson H Tsuno; Joji Kitayama; Yurai Okaji; Kentaro Yazawa; Masahiro Asakage; Shin Sasaki; Toshiaki Watanabe; Koki Takahashi; Hirokazu Nagawa
Epigallocatechin gallate induces apoptosis of monocytes.
The Journal of allergy and clinical immunology 2005;115(1):186-91.
2005: Keisuke Hata; Hironori Yamaguchi; Giichiro Tsurita; Soichi Watanabe; Kanako Wake; Masao Taki; Shoogo Ueno; Hirokazu Nagawa
Short term exposure to 1439 MHz pulsed TDMA field does not alter melatonin synthesis in rats.
Bioelectromagnetics 2005;26(1):49-53.
2004: Dai Shida; Joji Kitayama; Hironori Yamaguchi; Kotaro Hama; Junken Aoki; Hiroyuki Arai; Hiroharu Yamashita; Ken Mori; Akihiro Sako; Tsuyoshi Konishi; Toshiaki Watanabe; Teruyuki Sakai; Rika Suzuki; Hideo Ohta; Yoh Takuwa; Hirokazu Nagawa
Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells.
Experimental cell research 2004;301(2):168-78.
2004: Kota Yamamoto; Takashi Komiyama; Toshio Miyata; T Kitagawa; Toshimitsu Momose; Hiroshi Shigematsu; Hirokazu Nagawa
Contralateral stenosis as a risk factor for carotid endarterectomy measured by near infrared spectroscopy.
International angiology : a journal of the International Union of Angiology 2004;23(4):388-93.
2004: Katsuyuki Hoshina; Toshio Miyata; T Hatakeyama; Hiroshi Shigematsu; Hirokazu Nagawa
Hemodynamic influence of peripheral vascular occlusive disease on abdominal aortic aneurysms.
International angiology : a journal of the International Union of Angiology 2004;23(4):373-8.
2004: Yurai Okaji; Nelson H Tsuno; Joji Kitayama; Shinsuke Saito; Tsuyoshi Takahashi; Kazushige Kawai; Kentaro Yazawa; Masahiro Asakage; Takeshi Tsuchiya; Daisuke Sakurai; Naoyuki Tsuchiya; Katsushi Tokunaga; Koki Takahashi; Hirokazu Nagawa
A novel method for isolation of endothelial cells and macrophages from murine tumors based on Ac-LDL uptake and CD16 expression.
Journal of immunological methods 2004;295(1-2):183-93.
2004: Toshiaki Watanabe; Tomomichi Kiyomatsu; Takamitsu Kanazawa; Tomohiro Tada; Yasuhiro Komuro; Giichiro Tsurita; Tetsuichiro Muto; Hirokazu Nagawa
Chemoradiotherapy for rectal cancer: current status and perspectives.
International journal of clinical oncology 2004;9(6):475-83.
2004: Akihiro Hosaka; Hiroyuki Koyama; Toshihiro Kushibiki; Yasuhiko Tabata; Nobuhiro Nishiyama; Tetsuro Miyata; Hiroshi Shigematsu; Tsuyoshi Takato; Hirokazu Nagawa
Gelatin hydrogel microspheres enable pinpoint delivery of basic fibroblast growth factor for the development of functional collateral vessels.
Circulation 2004;110(21):3322-8.
2004: Dai Shida; Joji Kitayama; Hironori Yamaguchi; Hiroharu Yamashita; Ken Mori; Toshiaki Watanabe; Yutaka Yatomi; Hirokazu Nagawa
Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells.
FEBS letters 2004;577(3):333-8.
2004: T Tada; Tomomi Watanabe; Takamitsu Kanazawa; Shinsuke Kazama; Shinichiro Koketsu; Hirokazu Nagawa
Genetic characterization of colorectal cancers in young patients based on chromosomal loss and microsatellite instability.
Scandinavian journal of gastroenterology 2004;39(11):1134-40.
2004: Shinichiro Koketsu; Toshiaki Watanabe; Shinsuke Kazama; Soichiro Ishihara; Yasuhiro Komuro; Hirokazu Nagawa
What types of colorectal cancer overexpress the MAGE protein?
Hepato-gastroenterology 2004;51(60):1648-52.
2004: Shin Sasaki; Joji Kitayama; Toshiaki Watanabe; Tsuyoshi Konishi; Hirokazu Nagawa
Diffuse expression of hRFI is correlated with blood vessel invasion in gastric carcinoma.
Japanese journal of clinical oncology 2004;34(10):584-7.
2004: Kenji Takegami; Yukio Kaneko; Toshiaki Watanabe; Toshiyuki Maruyama; Yoichiro Matsumoto; Hirokazu Nagawa
Polyacrylamide gel containing egg white as new model for irradiation experiments using focused ultrasound.
Ultrasound in medicine & biology 2004;30(10):1419-22.
2004: Takuya Miyahara; Hiroyuki Koyama; Tetsuro Miyata; Hiroshi Shigematsu; Jun-Ichiro Inoue; Tsuyoshi Takato; Hirokazu Nagawa
Inflammatory signaling pathway containing TRAF6 contributes to neointimal formation via diverse mechanisms.
Cardiovascular research 2004;64(1):154-64.
2004: Dai Shida; Toshiaki Watanabe; Junken Aoki; Kotaro Hama; Joji Kitayama; Hirofumi Sonoda; Yasuhiro Kishi; Hironori Yamaguchi; Shin Sasaki; Akihiro Sako; Tsuyoshi Konishi; Hiroyuki Arai; Hirokazu Nagawa
Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer.
Laboratory investigation; a journal of technical methods and pathology 2004;84(10):1352-62.
2004: Sei Sasaki; Tomomi Watanabe; Tsuyoshi Konishi; Joji Kitayama; Hirokazu Nagawa
Effects of expression of hRFI on adenoma formation and tumor progression in colorectal adenoma-carcinoma sequence.
Journal of experimental & clinical cancer research : CR 2004;23(3):507-12.
2004: Hirokatsu Kinoshita; Toshiaki Watanabe; Akio Yanagisawa; Hirokazu Nagawa; Yo Kato; Tetsuichiro Muto
Pathological changes of advanced lower-rectal cancer by preoperative radiotherapy.
Hepato-gastroenterology 2004;51(59):1362-6.
2004: Makoto Ishikawa; Joji Kitayama; Shinsuke Kazama; Hirokazu Nagawa
The expression pattern of vascular endothelial growth factor C and D in human esophageal normal mucosa, dysplasia and neoplasia.
Hepato-gastroenterology 2004;51(59):1319-22.
2004: Katsuyuki Hoshina; Hiroyuki Koyama; Tetsuro Miyata; Hiroshi Shigematsu; Tsuyoshi Takato; Ronald L Dalman; Hirokazu Nagawa
Aortic wall cell proliferation via basic fibroblast growth factor gene transfer limits progression of experimental abdominal aortic aneurysm.
Journal of vascular surgery 2004;40(3):512-8.
2004: Toshiaki Watanabe; Takamitsu Kanazawa; Tomohiro Tada; Yoshihiro Kazama; Keisuke Hata; Hirokazu Nagawa
Chemotherapy and survival in colorectal cancer patients with and without microsatellite instability: can MSI be a prognostic marker?
Gastroenterology 2004;127(2):688-9; author reply 689-90.
2004: Yoshio Hosoi; Toshiaki Watanabe; Keiichi Nakagawa; Yoshihisa Matsumoto; Atsushi Enomoto; Akinori Morita; Hirokazu Nagawa; Norio Suzuki
Up-regulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer.
International journal of oncology 2004;25(2):461-8.
2004: Makoto Ishikawa; Joji Kitayama; Hirokazu Nagawa
Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(13):4325-31.
2004: Masahiro Asakage; Nelson H Tsuno; Joji Kitayama; Kazushige Kawai; Yurai Okaji; Kentaro Yazawa; Shoichi Kaisaki; Koki Takahashi; Hirokazu Nagawa
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (pravastatin) inhibits endothelial cell proliferation dependent on G1 cell cycle arrest.
Anti-cancer drugs 2004;15(6):625-32.
2004: Shinichiro Koketsu; Toshiaki Watanabe; Nobukazu Hori; Naoyuki Umetani; Yutaka Takazawa; Hirokazu Nagawa
Hemophagocytic syndrome caused by fulminant ulcerative colitis and cytomegalovirus infection: report of a case.
Diseases of the colon and rectum 2004;47(7):1250-3; discussion 1253-5.
2004: Yasuhiro Komuro; Toshiaki Watanabe; Takamitsu Kanazawa; Tomohiro Tada; Kazuhiko Fukatsu; Akihiro Hosaka; Keisuke Hata; Hirokazu Nagawa
A case of adrenal metastasis from rectal carcinoma without lung metastasis: evaluation for alteration of loss of heterozygosity and immunohistochemical expression.
Journal of gastroenterology 2004;39(6):594-5.
2004: Kazushige Kawai; Nelson H Tsuno; Joji Kitayama; Yurai Okaji; Kentaro Yazawa; Masahiro Asakage; Nobukazu Hori; Toshiaki Watanabe; Koki Takahashi; Hirokazu Nagawa
Epigallocatechin gallate attenuates adhesion and migration of CD8+ T cells by binding to CD11b.
The Journal of allergy and clinical immunology 2004;113(6):1211-7.
2004: Toshiaki Watanabe; Hirokazu Nagawa
Sphincter preservation in locally advanced rectal cancer due to the addition of continuous infusion 5-FU to preoperative radiation therapy or advances in surgical techniques?
International journal of radiation oncology, biology, physics 2004;59(2):618; author reply 618.
2004: Akihiro Sako; Joji Kitayama; Hiroyuki Koyama; Hikaru Ueno; Hiroaki Uchida; Hirofumi Hamada; Hirokazu Nagawa
Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer.
Cancer research 2004;64(10):3624-8.
2004: Akihiro Sako; Joji Kitayama; Shoichi Kaisaki; Hirokazu Nagawa
Hyperlipidemia is a risk factor for lymphatic metastasis in superficial esophageal carcinoma.
Cancer letters 2004;208(1):43-9.
2004: Shinichiro Koketsu; Toshiaki Watanabe; Hirokazu Nagawa
Expression of DNA repair protein: MYH, NTH1, and MTH1 in colorectal cancer.
Hepato-gastroenterology 2004;51(57):638-42.
2004: Makoto Ishikawa; Joji Kitayama; Hiroshi Nariko; Kimitoshi Kohno; Hirokazu Nagawa
The expression pattern of UDP-N-acetyl-alpha-d-galactosamine: polypeptide N-acetylgalactosaminyl transferase-3 in early gastric carcinoma.
Journal of surgical oncology 2004;86(1):28-33.
2004: Shinsuke Kazama; Joji Kitayama; Toshiaki Watanabe; Hirokazu Nagawa
Expression pattern of vascular endothelial growth factor-C in human colorectal normal mucosa and neoplastic mucosa.
Hepato-gastroenterology 2004;51(56):391-5.
2004: Y Komuro; Toshiaki Watanabe; Hirokazu Nagawa
Multiple confluent telangiectatic lesions following radiation treatment for prostate cancer.
Endoscopy 2004;36(3):252.
2004: Yasuhiro Komuro; Toshiaki Watanabe; Giichiro Tsurita; Tetsuichiro Muto; Hirokazu Nagawa
Survivin expression in ovarian carcinoma: correlation with apoptotic markers and prognosis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(2):264.
2004: Joji Kitayama; K Hatano; Shoichi Kaisaki; H Suzuki; S Fujii; Hirokazu Nagawa
Hyperlipidaemia is positively correlated with lymph node metastasis in men with early gastric cancer.
The British journal of surgery 2004;91(2):191-8.
2004: Joji Kitayama; Dai Shida; Akihiro Sako; Makoto Ishikawa; Kotaro Hama; Junken Aoki; Hiroyuki Arai; Hirokazu Nagawa
Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma.
Breast cancer research : BCR 2004;6(6):R640-6.
2004: Tsuyoshi Konishi; Toshiaki Watanabe; Joji Kitayama; Junji Shibahara; Takehiko Hiramatsu; Kosuke Hara; Ken Kuriki; Hirokazu Nagawa
Successfully treated idiopathic rectosigmoid perforation 7 years after renal transplantation.
Journal of gastroenterology 2004;39(5):484-9.
2004: Ikuo Nagashima; Tadahiro Takada; Keiji Matsuda; Miki Adachi; Hirokazu Nagawa; Tetsuichiro Muto; Kota Okinaga
A new scoring system to classify patients with colorectal liver metastases: proposal of criteria to select candidates for hepatic resection.
Journal of hepato-biliary-pancreatic surgery 2004;11(2):79-83.
2004: Kenji Takegami; Yoneei Kawaguchi; Hiroshi Nakayama; Yoshiro Kubota; Hirokazu Nagawa
Preoperative grading system for predicting operative conditions in laparoscopic cholecystectomy.
Surgery today 2004;34(4):331-6.
2004: Keisuke Hata; Toshiaki Watanabe; Toru Motoi; Hirokazu Nagawa
Pitfalls of pit pattern diagnosis in ulcerative colitis-associated dysplasia.
Gastroenterology 2004;126(1):374-6.
2004: Yurai Okaji; Nelson H Tsuno; Joji Kitayama; Shinsuke Saito; Tsuyoshi Takahashi; Kazushige Kawai; Kentaro Yazawa; Masahiro Asakage; Nobukazu Hori; Toshiaki Watanabe; Yoichi Shibata; Koki Takahashi; Hirokazu Nagawa
Vaccination with autologous endothelium inhibits angiogenesis and metastasis of colon cancer through autoimmunity.
Cancer science 2004;95(1):85-90.
2004: Masao Iida; Johji Imura; Teruhito Furuichi; Toshio Sawada; Hirokazu Nagawa; Takahiro Fujimori
Alteration of the AT motif binding factor-1 expression in alpha-fetoprotein producing gastric cancer: is it an event for differentiation and proliferation of the tumors?
Oncology reports 2004;11(1):3-7.
2003: Keisuke Hata; Toshiaki Watanabe; Yutaka J Kawamura; Hironori Ishigami; Takamitsu Kanazawa; Tomohiro Tada; Bin Zhao; Shinichiro Koketsu; Hirokazu Nagawa
K-ras mutation and loss of heterozygosity at 17p with beta-catenin accumulation in intramucosal carcinoma of the ileostomy in familial adenomatous polyposis: a case report.
Digestive diseases and sciences 2003;48(12):2310-4.
2003: Yasuhiro Komuro; Toshiaki Watanabe; Joji Kitayama; Hironori Yamaguchi; Nelson H Tsuno; Hirokazu Nagawa
The Immunohistochemical expression of endothelial cell differentiation gene-2 receptor in human colorectal adenomas.
Hepato-gastroenterology 2003;50(54):1770-3.
2003: Tomohiro Tada; Toshiaki Watanabe; Shinsuke Kazama; Takamitsu Kanazawa; Keisuke Hata; Yasuhiro Komuro; Hirokazu Nagawa
Reduced p16 expression correlates with lymphatic invasion in colorectal cancers.
Hepato-gastroenterology 2003;50(54):1756-60.
2003: Shinichiro Koketsu; Toshiaki Watanabe; Tomohiro Tada; Takamitsu Kanazawa; Eiji Ueda; Hirokazu Nagawa
Sporadic colorectal cancer in elderly people.
Hepato-gastroenterology 2003;50(54):1749-52.
2003: Hiroaki Nozawa; Toshiaki Watanabe; Tatsuya Ohnishi; Tomohiro Tada; Giichiro Tsurita; Shin Sasaki; Joji Kitayama; Hirokazu Nagawa
Detection of cancer cells in mesenteric vein and peripheral vessels by measuring telomerase activity in patients with colorectal cancer.
Surgery 2003;134(5):791-8.
2003: Kazushige Kawai; Nelson H Tsuno; Joji Kitayama; Yurai Okaji; Kentaro Yazawa; Masahiro Asakage; Nobukazu Hori; Toshiaki Watanabe; Koki Takahashi; Hirokazu Nagawa
Epigallocatechin gallate, the main component of tea polyphenol, binds to CD4 and interferes with gp120 binding.
The Journal of allergy and clinical immunology 2003;112(5):951-7.
2003: Akihiro Sako; Joji Kitayama; Hironori Yamaguchi; Shoichi Kaisaki; Hiroyuki Suzuki; Kazuhiko Fukatsu; Shin Fujii; Hirokazu Nagawa
Vascular endothelial growth factor synthesis by human omental mesothelial cells is augmented by fibroblast growth factor-2: possible role of mesothelial cell on the development of peritoneal metastasis.
The Journal of surgical research 2003;115(1):113-20.
2003: K Hata; Tomomi Watanabe; Shinsuke Kazama; K Suzuki; M Shinozaki; Takashi Yokoyama; K Matsuda; Tetsuichiro Muto; Hirokazu Nagawa
Earlier surveillance colonoscopy programme improves survival in patients with ulcerative colitis associated colorectal cancer: results of a 23-year surveillance programme in the Japanese population.
British journal of cancer 2003;89(7):1232-6.
2003: Keisuke Hata; Tomomi Watanabe; Masaru Shinozaki; Hirokazu Nagawa
Patients with extraintestinal manifestations have a higher risk of developing pouchitis in ulcerative colitis: multivariate analysis.
Scandinavian journal of gastroenterology 2003;38(10):1055-8.
2003: Hironori Yamaguchi; Joji Kitayama; Noriko Takuwa; Kayo Arikawa; Isao Inoki; Kazuhiko Takehara; Hirokazu Nagawa; Yoh Takuwa
Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells.
The Biochemical journal 2003;374(Pt 3):715-22.
2003: S Saito; Joji Kitayama; Z X Jin; Nelson H Tsuno; Shoichi Kaisaki; Y Seto; Hirokazu Nagawa
Beta-chemokine, macrophage inflammatory protein-1beta (MIP-1beta), is highly expressed in diffuse type human gastric cancers.
Journal of experimental & clinical cancer research : CR 2003;22(3):453-9.
2003: Shin Sasaki; Toshiaki Watanabe; Tsuyoshi Konishi; Hirokazu Nagawa
[Expression of hRFI in digestive system cancer].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 7():242-6.
2003: Shin Sasaki; Toshiaki Watanabe; Hirokazu Nagawa
[Genetics of colon carcinogenesis].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 7():72-4.
2003: Kayo Arikawa; Noriko Takuwa; Hironori Yamaguchi; Naotoshi Sugimoto; Joji Kitayama; Hirokazu Nagawa; Kazuhiko Takehara; Yoh Takuwa
Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity.
The Journal of biological chemistry 2003;278(35):32841-51.
2003: Takamitsu Kanazawa; Toshiaki Watanabe; Hirokazu Nagawa
Does early polypoid colorectal cancer with depression have a pathway other than adenoma-carcinoma sequence?
Tumori 2003;89(4):408-11.
2003: Yasuhiro Komuro; Toshiaki Watanabe; Nelson H Tsuno; Joji Kitayama; Naohito Inagaki; Miwa Nishida; Hirokazu Nagawa
The usefulness of immunohistochemical evaluation of dihydropyrimidine dehydrogenase for rectal cancer treated with preoperative radiotherapy.
Hepato-gastroenterology 2003;50(52):906-11.
2003: Yasuhiro Komuro; Tomomi Watanabe; Yoshio Hosoi; Yoshihisa Matsumoto; Keiichi Nakagawa; S Saito; Soichiro Ishihara; Shinsuke Kazama; Nelson H Tsuno; Joji Kitayama; Norio Suzuki; Giichiro Tsurita; Tetsuichiro Muto; Hirokazu Nagawa
Prediction of tumor radiosensitivity in rectal carcinoma based on p53 and Ku70 expression.
Journal of experimental & clinical cancer research : CR 2003;22(2):223-8.
2003: Akio Hidemura; Hideaki Saito; Kazuhiko Fukatsu; Shigeo Ikeda; Joji Kitayama; Takeaki Matsuda; Hirokazu Nagawa
Patients with postoperative infections have sticky neutrophils before operation.
Shock (Augusta, Ga.) 2003;19(6):497-502.
2003: Woodae Kang; Hideaki Saito; Kazuhiko Fukatsu; Hirokazu Nagawa; Shigeo Ikeda
Brief refeeding rapidly reverses dietary restriction-induced nuclear factor-kappaB downregulation in peritoneal resident cells.
JPEN. Journal of parenteral and enteral nutrition 2003;27(3):193-7; discussion 197.
2003: Hironori Yamaguchi; Giichiro Tsurita; Shoogo Ueno; Soichi Watanabe; Kanako Wake; Masao Taki; Hirokazu Nagawa
1439 MHz pulsed TDMA fields affect performance of rats in a T-maze task only when body temperature is elevated.
Bioelectromagnetics 2003;24(4):223-30.
2003: Hiroaki Uchida; Nobusada Shinoura; Joji Kitayama; Toshiaki Watanabe; Hirokazu Nagawa; Hirofumi Hamada
5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells.
The journal of gene medicine 2003;5(4):287-99.
2003: Dai Shida; Joji Kitayama; Hironori Yamaguchi; Yurai Okaji; Nelson H Tsuno; Toshiaki Watanabe; Yoh Takuwa; Hirokazu Nagawa
Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1.
Cancer research 2003;63(7):1706-11.
2003: Tadahiko Masaki; Hiroyoshi Matsuoka; Masanori Sugiyama; Nobutsugu Abe; Toshiyuki Mori; Yutaka Atomi; Toshiaki Watanabe; Hirokazu Nagawa; Tetsuichiro Muto
Budding as a useful determinant of the optimal treatment for T1 rectal carcinomas.
Hepato-gastroenterology 2003;50(50):388-91.
2003: Akio Hidemura; Hideaki Saito; Kazuhiko Fukatsu; Takeaki Matsuda; Joji Kitayama; Shigeo Ikeda; Woodae Kang; Hirokazu Nagawa
Oral administration of Bifidobacterium longum culture condensate in a diet-restricted murine peritonitis model enhances polymorphonuclear neutrophil recruitment into the local inflammatory site.
Nutrition (Burbank, Los Angeles County, Calif.) 2003;19(3):270-4.
2003: Masahiro Kato; Joji Kitayama; Shinsuke Kazama; Hirokazu Nagawa
Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma.
Breast cancer research : BCR 2003;5(5):R144-50.
2003: Kenji Takegami; Yoneei Kawaguchi; Hiroshi Nakayama; Yoshiro Kubota; Hirokazu Nagawa
Minilaparotomy approach to colon cancer.
Surgery today 2003;33(6):414-20.
2003: Kenji Takegami; Yonei Kawaguchi; Hiroshi Nakayama; Yoshiro Kubota; Hirokazu Nagawa
Impact of a clinical pathway and standardization of treatment for acute appendicitis.
Surgery today 2003;33(5):336-41.
2003: Shinsuke Saito; Nelson H Tsuno; Eiji Sunami; Nobukazu Hori; Joji Kitayama; Shinsuke Kazama; Yurai Okaji; Kazushige Kawai; Takamitsu Kanazawa; Toshiaki Watanabe; Yoichi Shibata; Hirokazu Nagawa
Expression of platelet-derived endothelial cell growth factor in inflammatory bowel disease.
Journal of gastroenterology 2003;38(3):229-37.
2003: Tomohiro Takenoue; Yoshinao Yamada; Seiichiro Miyagawa; Hirokazu Nagawa
Intussusception up to splenic flexure by cecal carcinoma in an adult: report of a case.
Hepato-gastroenterology 2003;50(49):95-8.
2003: Makoto Ishikawa; Joji Kitayama; Shinsuke Kazama; Hirokazu Nagawa
Expression of vascular endothelial growth factor C and D (VEGF-C and -D) is an important risk factor for lymphatic metastasis in undifferentiated early gastric carcinoma.
Japanese journal of clinical oncology 2003;33(1):21-7.
2003: Koji Sawada; Tetsuichiro Muto; Takashi Shimoyama; Masamichi Satomi; Toshio Sawada; Hirokazu Nagawa; Nobuo Hiwatashi; Hitoshi Asakura; Toshifumi Hibi
Multicenter randomized controlled trial for the treatment of ulcerative colitis with a leukocytapheresis column.
Current pharmaceutical design 2003;9(4):307-21.
2002: S Fujii; Joji Kitayama; Shoichi Kaisaki; Sei Sasaki; Y Seto; O Tominaga; Nelson H Tsuno; Naoyuki Umetani; H Yokota; K Kitamura; Takashi Tsuruo; Hirokazu Nagawa
Carcinoembryonic antigen mRNA in abdominal cavity as a useful predictor of peritoneal recurrence of gastric cancer with serosal exposure.
Journal of experimental & clinical cancer research : CR 2002;21(4):547-53.
2002: Takamitsu Kanazawa; Toshiaki Watanabe; Shinsuke Kazama; Toshihiro Tada; Shinichiro Koketsu; Hirokazu Nagawa
Poorly differentiated adenocarcinoma and mucinous carcinoma of the colon and rectum show higher rates of loss of heterozygosity and loss of E-cadherin expression due to methylation of promoter region.
International journal of cancer. Journal international du cancer 2002;102(3):225-9.
2002: Hiroshi Yasuhara; Shuji Naka; Hironobu Yanagie; Hirokazu Nagawa
Influence of diabetes on persistent nonhealing ischemic foot ulcer in end-stage renal disease.
World journal of surgery 2002;26(11):1360-4.
2002: Yasuhiro Komuro; Toshiaki Watanabe; Yoshio Hosoi; Yoshihisa Matsumoto; Keiichi Nakagawa; Nelson H Tsuno; Shinsuke Kazama; Joji Kitayama; Norio Suzuki; Hirokazu Nagawa
The expression pattern of Ku correlates with tumor radiosensitivity and disease free survival in patients with rectal carcinoma.
Cancer 2002;95(6):1199-205.
2002: Shogo Kikuchi; Toshifusa Nakajima; Osamu Kobayashi; Tatsuo Yamazaki; Masahiro Kikuichi; Kiyoshi Mori; Shinsuke Oura; Hideaki Watanabe; Hirokazu Nagawa; Reiji Otani; Naoyuki Okamoto; Michiko Kurosawa; Haruyuki Anzai; Toshiro Konishi; Shunji Futagawa; Noboru Mizobuchi; Oichiro Kobori; Ruriko Kaise; Yutaka Inaba; Osamu Wada
U-shaped effect of drinking and linear effect of smoking on risk for stomach cancer in Japan.
Japanese journal of cancer research : Gann 2002;93(9):953-9.
2002: Shin Sasaki; Tatsuya Nakamura; Hirofumi Arakawa; Masaki Mori; Toshiaki Watanabe; Hirokazu Nagawa; Carlo M Croce
Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer.
Oncogene 2002;21(32):5024-30.
2002: Toshiaki Watanabe; Giichiro Tsurita; Tetsuichiro Muto; Toshio Sawada; Koki Sunouchi; Yoshiki Higuchi; Yasuhiro Komuro; Takamitsu Kanazawa; Takeru Iijima; Michiko Miyaki; Hirokazu Nagawa
Extended lymphadenectomy and preoperative radiotherapy for lower rectal cancers.
Surgery 2002;132(1):27-33.
2002: H Nakayama; Joji Kitayama; Hirokazu Nagawa
Rat gastric adenocarcinoma cell line BV9 avidly adheres to lymphatic endothelium under lymphatic flow condition.
Journal of experimental & clinical cancer research : CR 2002;21(2):289-94.
2002: Eiji Ueda; Tomomi Watanabe; Naoyuki Umetani; Hironori Ishigami; Sei Sasaki; Hirokazu Nagawa
Microsatellite instability of cancers and concomitant adenomas in synchronous multiple colorectal cancer patients.
Journal of experimental & clinical cancer research : CR 2002;21(2):149-54.
2002: Tatsuaki Ishiguro; Hironori Yamaguchi; Hirokazu Nagawa
The formulated growth of early gastric cancer.
Hepato-gastroenterology 2002;49(45):887-8.
2002: H Hasebe; K Sato; Hironobu Yanagie; Yasutaka Takeda; Y Nonaka; T A Takahashi; Masazumi Eriguchi; Hirokazu Nagawa
Bcl-2, Bcl-xL and c-FLIP(L) potentially regulate the susceptibility of human peripheral blood monocyte-derived dendritic cells to cell death at different developmental stages.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2002;56(3):144-51.
2002: Hiroaki Nozawa; Hajime Tsukui; Koichiro Nishida; Kazuhiro Yakumaru; Hirokazu Nagawa; Takayoshi Sekikawa
Dihydropyrimidine dehydrogenase expression in preoperative biopsy and surgically resected specimens of gastric carcinoma.
Cancer chemotherapy and pharmacology 2002;49(4):267-73.
2002: Hiroaki Uchida; Nobusada Shinoura; Joji Kitayama; Toshiaki Watanabe; Hirokazu Nagawa; Hirofumi Hamada
Caspase-8 gene transduction augments radiation-induced apoptosis in DLD-1 cells.
Biochemical and biophysical research communications 2002;292(2):347-54.
2002: Takuya Osada; Hirokazu Nagawa; Tsuyoshi Takahashi; Nelson H Tsuno; Joji Kitayama; Yoichi Shibata
Dendritic cells cultured in anti-CD40 antibody-immobilized plates elicit a highly efficient peptide-specific T-cell response.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2002;25(2):176-84.
2002: Tatsuaki Ishiguro; Chizuru Ishiguro; Goichi Ishiguro; Hirokazu Nagawa
Midazolam sedation for upper gastrointestinal endoscopy: comparison between the states of patients in partial and complete amnesia.
Hepato-gastroenterology 2002;49(44):438-40.
2002: Shinsuke Kazama; Yoichi Ajioka; Hidenobu Watanabe; Toshiaki Watanabe; Hirokazu Nagawa
Histogenesis and morphogenesis of depressed-type early colorectal carcinoma.
Pathology international 2002;52(2):119-25.
2002: Shinsuke Kazama; Yoichi Ajioka; Hidenobu Watanabe; Toshiaki Watanabe; Hirokazu Nagawa
Not infrequent K-ras mutations in depressed-type early colorectal carcinomas larger than 10 mm.
Japanese journal of cancer research : Gann 2002;93(2):178-83.
2002: Takuya Osada; Joji Kitayama; Hirokazu Nagawa
Cholesterol granuloma of the breast mimicking carcinoma: report of a case.
Surgery today 2002;32(11):981-4.
2002: Eiji Sunami; Nelson H Tsuno; Joji Kitayama; Shinsuke Saito; Takuya Osada; Hironori Yamaguchi; Shigeru Tomozawa; Takashi Tsuruo; Yoichi Shibata; Hirokazu Nagawa
Decreased synthesis of matrix metalloproteinase-7 and adhesion to the extracellular matrix proteins of human colon cancer cells treated with troglitazone.
Surgery today 2002;32(4):343-50.
2002: Eiji Ueda; Joji Kitayama; Yasuyuki Seto; Toru Motoi; Hirokazu Nagawa
Postoperative complications after local resection of the stomach.
Surgery today 2002;32(4):305-9.
2002: Keisuke Hata; Nobutaka Tanaka; Yukihiro Nomura; Ikuo Wada; Hirokazu Nagawa
Early appendiceal adenocarcinoma. A review of the literature with special reference to optimal surgical procedures.
Journal of gastroenterology 2002;37(3):210-4.
2001: Ayako Tateishi; H Mitsui; T Oki; J Morishita; H Maekawa; Naoya Yahagi; T Maruyama; M Ichinose; S Ohnishi; Yasushi Shiratori; M Minami; S Koutetsu; N Hori; Toshiaki Watanabe; Hirokazu Nagawa; Masao Omata
Extensive mesenteric vein and portal vein thrombosis successfully treated by thrombolysis and anticoagulation.
Journal of gastroenterology and hepatology 2001;16(12):1429-33.
2001: T Osada; Hirokazu Nagawa; Joji Kitayama; Nelson H Tsuno; Soichiro Ishihara; Masaru Takamizawa; Yoichi Shibata
Peripheral blood dendritic cells, but not monocyte-derived dendritic cells, can augment human NK cell function.
Cellular immunology 2001;213(1):14-23.
2001: H Maekawa; Naomi Tanaka; N Hashimoto; H Yamada; Hiroshi Mitsui; H Ikeda; Toshiyuki Maruyama; Masatomo Mori; Hirokazu Nagawa; Satoshi Kimura
Esophageal smooth muscle tumor in a 25-year-old woman with congenital malformations.
Journal of gastroenterology 2001;36(10):700-3.
2001: J Yano HKitayama; K Hatano; Nelson H Tsuno; T Osada; Tomomi Watanabe; Takashi Tsuruo; Tetsuichiro Muto; Hirokazu Nagawa
Clustered cancer cells show a distinct adhesion behavior from single cell form under physiological shear conditions.
Journal of experimental & clinical cancer research : CR 2001;20(3):407-12.
2001: Hirokazu Nagawa; Tetsuichiro Muto; Koki Sunouchi; Yoshiki Higuchi; Giichiro Tsurita; Tomomi Watanabe; Toshio Sawada
Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy.
Diseases of the colon and rectum 2001;44(9):1274-80.
2001: Hiroshi Yasuhara; N Ohara; Hirokazu Nagawa
Influence of gender on intraluminal thrombus of abdominal aortic aneurysms.
American journal of surgery 2001;182(1):89-92.
2001: Tomohiro Takenoue; Yoshinao Yamada; Seiichiro Miyagawa; Yoshimitsu Akiyama; Hirokazu Nagawa
Krukenberg tumor from gastric mucosal carcinoma without lymphatic or venous invasion: report of a case.
Hepato-gastroenterology 2001;48(40):1211-4.
2001: J Kitayama; T Inoue; Hirokazu Nagawa; Hideaki Saito
[Perioperative risk factors and its evaluation in the operation for gastric cancer of aged patients].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 4():604-10.
2001: K Hata; Joji Kitayama; M Shinozaki; Y Komuro; Tomomi Watanabe; T Takano; S Iwase; Hirokazu Nagawa
Intestinal perforation due to metastasis of breast carcinoma, with special reference to chemotherapy: a case report.
Japanese journal of clinical oncology 2001;31(4):162-4.
2001: T Ishiguro; Hirokazu Nagawa
Inadvertent endoscopic application of a hemoclip to the splenic artery through a perforated gastric ulcer.
Gastrointestinal endoscopy 2001;53(3):378-9.
2001: Takuya Osada; Hirokazu Nagawa; Tadahiko Masaki; Nelson H Tsuno; Eiji Sunami; Tomomi Watanabe; Tetsuichiro Muto; Y Shibata
Thoracic empyema associated with recurrent colon cancer: report of a case and review of the literature.
Diseases of the colon and rectum 2001;44(2):291-4.
2001: T Ishiguro; Hirokazu Nagawa
ATF3 gene regulates cell form and migration potential of HT29 colon cancer cells.
Oncology research 2001;12(8):343-6.
2001: Eiji Ueda; Tomomi Watanabe; Hironori Ishigami; Naoyuki Umetani; Sei Sasaki; Shinichiro Koketsu; Hirokazu Nagawa
Microsatellite instability of colorectal cancer and adenoma in synchronous multiple colorectal cancer patients with associated extracolonic malignancies.
Surgery today 2001;31(5):405-9.
2001: Naoyuki Umetani; Tetsuichiro Muto; Yutaka J Kawamura; Tsutomu Watanabe; T Nakajima; Hirokazu Nagawa
Superficial depressed early carcinoma that developed into protuberant advanced carcinoma in the transverse colon.
Journal of gastroenterology 2001;36(1):48-51.
2000: S Ishihara; Tomomi Watanabe; Naoyuki Umetani; S Yamagata; Tadahiko Masaki; Hirokazu Nagawa; Tetsuichiro Muto
Small advanced colorectal cancers: clinicopathological characteristics and pathogenetic origin.
Japanese journal of clinical oncology 2000;30(11):504-9.
2000: Naoyuki Umetani; Tomomi Watanabe; Sei Sasaki; Hirokazu Nagawa
Rectosigmoidal adenomatous polyposis: a novel entity of polyposis? Report of a case.
Diseases of the colon and rectum 2000;43(10):1439-43.
2000: M Shinozaki; Tomomi Watanabe; Y Kubota; Toshio Sawada; Hirokazu Nagawa; Tetsuichiro Muto
High proliferative activity is associated with dysplasia in ulcerative colitis.
Diseases of the colon and rectum 2000;43(10 Suppl):S34-9.
2000: T Ishiguro; Hirokazu Nagawa; M Naito; Takashi Tsuruo
Inhibitory effect of ATF3 antisense oligonucleotide on ectopic growth of HT29 human colon cancer cells.
Japanese journal of cancer research : Gann 2000;91(8):833-6.
2000: Marcelo Eidi Nita; Suzane Kioko Ono-Nita; Nelson H Tsuno; O Tominaga; Tomohiro Takenoue; Eiji Sunami; Joji Kitayama; Yusuke Nakamura; Hirokazu Nagawa
Bcl-X(L) antisense sensitizes human colon cancer cell line to 5-fluorouracil.
Japanese journal of cancer research : Gann 2000;91(8):825-32.
2000: Shogo Kikuchi; T Nakajima; Osamu Kobayashi; T Yamazaki; M Kikuichi; Kiyoshi Mori; S Oura; H Watanabe; Hirokazu Nagawa; R Otani; N Okamoto; Michiko Kurosawa; H Anzai; T Kubo; T Konishi; Shunji Futagawa; Noboru Mizobuchi; O Kobori; R Kaise; T Sato; Yutaka Inaba; Osamu Wada
Effect of age on the relationship between gastric cancer and Helicobacter pylori. Tokyo Research Group of Prevention for Gastric Cancer.
Japanese journal of cancer research : Gann 2000;91(8):774-9.
2000: Shigeru Tomozawa; Nelson H Tsuno; Eiji Sunami; K Hatano; Joji Kitayama; Takuya Osada; Shinsuke Saito; Takashi Tsuruo; Yoichi Shibata; Hirokazu Nagawa
Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer.
British journal of cancer 2000;83(3):324-8.
2000: Joji Kitayama; Akio Hidemura; Hiroaki Saito; Hirokazu Nagawa
Shear stress affects migration behavior of polymorphonuclear cells arrested on endothelium.
Cellular immunology 2000;203(1):39-46.
2000: Y Seto; T Ishida; Hirokazu Nagawa; Michio Kaminishi
Vascular invasion of early gastric cancer at resection line.
International surgery 2000;85(3):216-8.
2000: H Nakayama; Joji Kitayama; Tetsuichiro Muto; Hirokazu Nagawa
Characterization of intracellular cytokine profile of CD4(+) T cells in peripheral blood and tumor-draining lymph nodes of patients with gastrointestinal cancer.
Japanese journal of clinical oncology 2000;30(7):301-5.
2000: Giichiro Tsurita; Hirokazu Nagawa; Shoogo Ueno; Soichi Watanabe; Masao Taki
Biological and morphological effects on the brain after exposure of rats to a 1439 MHz TDMA field.
Bioelectromagnetics 2000;21(5):364-71.
2000: Naoyuki Umetani; Sei Sasaki; Tomomi Watanabe; Hironori Ishigami; Eiji Ueda; Hirokazu Nagawa
Diagnostic primer sets for microsatellite instability optimized for a minimal amount of damaged DNA from colorectal tissue samples.
Annals of surgical oncology 2000;7(4):276-80.
2000: T Ishiguro; Hirokazu Nagawa; M Naito; T Tsuruo
Analysis of novel metastasis-associated gene TI-227.
Japanese journal of cancer research : Gann 2000;91(4):390-4.
2000: Tomohiro Takenoue; Hirokazu Nagawa; K Matsuda; S Fujii; Marcelo Eidi Nita; K Hatano; Joji Kitayama; Takashi Tsuruo; Tetsuichiro Muto
Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method.
Annals of surgical oncology 2000;7(3):193-8.
2000: Tomohiro Takenoue; Joji Kitayama; Y Takei; Naoyuki Umetani; K Matsuda; Marcelo Eidi Nita; K Hatano; Takashi Tsuruo; Hirokazu Nagawa
Characterization of dihydropyrimidine dehydrogenase on immunohistochemistry in colon carcinoma, and correlation between immunohistochemical score and protein level or messenger RNA expression.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(3):273-9.
2000: Bin Zhao; Wataru Kimura; N Futakawa; Hideki Abe; Joji Kitayama; Hirokazu Nagawa; Makuuchi Masatoshi
Significance of thymidine phosphorylase/platelet-derived endothelial cell growth factor in carcinoma of the papilla of Vater.
Japanese journal of cancer research : Gann 2000;91(3):331-6.
2000: K Matsuda; Tadahiko Masaki; Tomomi Watanabe; Joji Kitayama; Hirokazu Nagawa; Tetsuichiro Muto; Y Ajioka
Clinical significance of MUC1 and MUC2 mucin and p53 protein expression in colorectal carcinoma.
Japanese journal of clinical oncology 2000;30(2):89-94.
2000: Joji Kitayama; S Ikeda; K Kumagai; Hiroaki Saito; Hirokazu Nagawa
Alpha 6 beta 1 integrin (VLA-6) mediates leukocyte tether and arrest on laminin under physiological shear flow.
Cellular immunology 2000;199(2):97-103.
2000: T Ishiguro; Hirokazu Nagawa
Expression of the ATF3 gene on cell lines and surgically excised specimens.
Oncology research 2000;12(4):181-3.
2000: Nobuyuki Matsuhashi; Ayako Nakajima; K Watanabe; Yukiko Komeno; A Suzuki; S Ohnishi; Masao Omata; K Kondo; Y Usui; Junichi Iwadare; Tsutomu Watanabe; Hirokazu Nagawa; Tetsuichiro Muto
Tacrolimus in corticosteroid-resistant ulcerative colitis.
Journal of gastroenterology 2000;35(8):635-40.
2000: Yutaka J Kawamura; H Uchida; Tsutomu Watanabe; Hirokazu Nagawa
Early feeding after oncological colorectal surgery in Japanese patients.
Journal of gastroenterology 2000;35(7):524-7.
2000: Eiji Sunami; Nelson H Tsuno; Takuya Osada; Shinsuke Saito; Joji Kitayama; Shigeru Tomozawa; Takashi Tsuruo; Yoichi Shibata; Tetsuichiro Muto; Hirokazu Nagawa
MMP-1 is a prognostic marker for hematogenous metastasis of colorectal cancer.
The oncologist 2000;5(2):108-14.
2000: Joji Kitayama; Nelson H Tsuno; Eiji Sunami; Takuya Osada; T Muto; Hirokazu Nagawa
E-selectin can mediate the arrest type of adhesion of colon cancer cells under physiological shear flow.
European journal of cancer (Oxford, England : 1990) 2000;36(1):121-7.
2000: Shinsuke Saito; Nelson H Tsuno; Hirokazu Nagawa; Eiji Sunami; J Zhengxi; Takuya Osada; Joji Kitayama; Yoichi Shibata; T Tsuruo; T Muto
Expression of platelet-derived endothelial cell growth factor correlates with good prognosis in patients with colorectal carcinoma.
Cancer 2000;88(1):42-9.
1999: Hirokazu Nagawa; Tetsuichiro Muto
[Molecular biology in the development of colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26(14):2147-53.
1999: Shigeru Tomozawa; Hirokazu Nagawa; Nelson H Tsuno; K Hatano; Takuya Osada; Joji Kitayama; Eiji Sunami; Marcelo Eidi Nita; S Ishihara; H Yano; Takashi Tsuruo; Yoichi Shibata; Tetsuichiro Muto
Inhibition of haematogenous metastasis of colon cancer in mice by a selective COX-2 inhibitor, JTE-522.
British journal of cancer 1999;81(8):1274-9.
1999: Tomohiro Takenoue; Yoshinao Yamada; Seiichiro Miyagawa; Yoshimitsu Akiyama; K Koyama; Hirokazu Nagawa
Cisplatin-5-fluorouracil therapy with remarkable effect and 5-year survival for paraaortic lymph node metastases of rectal carcinoma in females: a case report.
Japanese journal of clinical oncology 1999;29(11):582-6.
1999: K Matsuda; Tadahiko Masaki; S Ishii; Hideomi Yamashita; Tomomi Watanabe; Hirokazu Nagawa; Tetsuichiro Muto; Yasunobu Hirata; Kenjiro Kimura; Somei Kojima
Possible associations of rectal carcinoma with Schistosoma japonicum infection and membranous nephropathy: a case report with a review.
Japanese journal of clinical oncology 1999;29(11):576-81.
1999: M Shinozaki; Tetsuji Sawada; Tomomi Watanabe; Hironori Ishigami; Hirokazu Nagawa
[Influencing factors on occurrence and relapse in ulcerative colitis].
Nihon rinsho. Japanese journal of clinical medicine 1999;57(11):2420-5.
1999: M Shinozaki; Tetsuichiro Muto; K Suzuki; K Matsuda; T Yokoyama; Tomomi Watanabe; T Masaki; Hiroshi Sato; S Araki; Hirokazu Nagawa
Chronic active desease refext cancer riski in ulcreative collitis.
Japanese journal of cancer research : Gann 1999;90(10):1066-70.
1999: Giichiro Tsurita; Shoogo Ueno; Nelson H Tsuno; Hirokazu Nagawa; Tetsuichiro Muto
Effects of exposure to repetitive pulsed magnetic stimulation on cell proliferation and expression of heat shock protein 70 in normal and malignant cells.
Biochemical and biophysical research communications 1999;261(3):689-94.
1999: Joji Kitayama; Hirokazu Nagawa; Nelson H Tsuno; Takuya Osada; K Hatano; Eiji Sunami; Hiroaki Saito; Tetsuichiro Muto
Laminin mediates tethering and spreading of colon cancer cells in physiological shear flow.
British journal of cancer 1999;80(12):1927-34.
1999: Joji Kitayama; N Tuno; H Nakayama; Yoichi Shibata; Tetsuichiro Muto; Hirokazu Nagawa
Functional down-regulation of beta1 and beta2 integrins of lamina propria lymphocytes (LPL) and tumor-infiltrating lymphocytes (TIL) in colorectal cancer patients.
Annals of surgical oncology 1999;6(5):500-6.
1999: Marcelo Eidi Nita; Hirokazu Nagawa; O Tominaga; Nelson H Tsuno; K Hatano; Joji Kitayama; Takashi Tsuruo; C E Domene; Tetsuichiro Muto
p21Waf1/Cip1 expression is a prognostic marker in curatively resected esophageal squamous cell carcinoma, but not p27Kip1, p53, or Rb.
Annals of surgical oncology 1999;6(5):481-8.
1999: Joji Kitayama; Hirokazu Nagawa; H Nakayama; N Tuno; Yoichi Shibata; Tetsuichiro Muto
Functional expression of beta1 and beta2 integrins on tumor infiltrating lymphocytes (TILs) in colorectal cancer.
Journal of gastroenterology 1999;34(3):327-33.
1999: Yasuyuki Seto; Hirokazu Nagawa; Y Muto; Shoichi Kaizaki; Joji Kitayama; Tetsuichiro Muto
Preliminary report on local resection with lymphadenectomy for early gastric cancer.
The British journal of surgery 1999;86(4):526-8.
1999: Yasuyuki Seto; Hirokazu Nagawa; Joji Kitayama; Tetsuichiro Muto
Exposure and dissection of the root of the right gastric artery during gastric surgery.
Surgery today 1999;29(11):1229-30.
1999: Tomohiro Takenoue; Wataru Kimura; G Ishimaru; N Futakawa; I Han; T Inoue; H Shinkai; Bin Zhao; Y Wada; Hirokazu Nagawa; Tetsuichiro Muto
Giant solid cystic tumor of the pancreas with a fibrous septum caused by extracapsular growth in middle-aged woman: report of a case.
Surgery today 1999;29(11):1172-6.
1999: Y Seto; Hirokazu Nagawa; Masatomo Mori; Takashi Tsuruo; Tetsuichiro Muto
Effect of 5-fluorouracil on gastrointestinal carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats.
Digestive diseases and sciences 1999;44(1):75-8.
1999: Shin-Ya Sameshima; K Sakai; Hirokazu Nagawa; Nelson H Tsuno; Joji Kitayama; Tetsuichiro Muto
Correlation of the therapeutic effect of activated tumor-draining lymph node cells with specific interferon-gamma production in vitro.
Surgery today 1999;29(1):55-62.
1998: S Fujii; O Tominaga; Hirokazu Nagawa; Nelson H Tsuno; Marcelo Eidi Nita; Takashi Tsuruo; Tetsuichiro Muto
Quantitative analysis of the cyclin expression in human esophageal cancer cell lines.
Journal of experimental & clinical cancer research : CR 1998;17(4):491-6.
1998: Marcelo Eidi Nita; O Tominaga; Hirokazu Nagawa; Takashi Tsuruo; Tetsuichiro Muto
Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
Hepato-gastroenterology 1998;45(24):2117-22.
1998: Marcelo Eidi Nita; Hirokazu Nagawa; O Tominaga; Nelson H Tsuno; S Fujii; Sei Sasaki; Chuan-gang Fu; Tomohiro Takenoue; Takashi Tsuruo; Tetsuichiro Muto
5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins.
British journal of cancer 1998;78(8):986-92.
1998: Sei Sasaki; Tadahiko Masaki; Naoyuki Umetani; M Shinozaki; T Yokoyama; M Ono; Hirokazu Nagawa; Tetsuichiro Muto
Microsatellite instability is associated with the macroscopic configuration of neoplasms in patients with multiple colorectal adenomas.
Japanese journal of clinical oncology 1998;28(7):427-30.
1998: W S Tsai; Hirokazu Nagawa; Shoichi Kaizaki; T Tsuruo; Tetsuichiro Muto
Inhibitory effects of n-3 polyunsaturated fatty acids on sigmoid colon cancer transformants.
Journal of gastroenterology 1998;33(2):206-12.
1998: O Tominaga; Marcelo Eidi Nita; Hirokazu Nagawa; Tetsuichiro Muto
Screening for APC mutations based on detection of truncated APC proteins.
Digestive diseases and sciences 1998;43(2):306-10.
1998: Yasuyuki Seto; Hirokazu Nagawa; Shoichi Kaizaki; Hiroshi Nakayama; Tetsuichiro Muto
Complete dissection of the lymph nodes located along and at the roots of the left gastroepiploic vessels during distal gastrectomy.
Surgery today 1998;28(11):1221-3.
1998: Chuan-gang Fu; O Tominaga; Hirokazu Nagawa; Marcelo Eidi Nita; T Masaki; G Ishimaru; Y Higuchi; Takashi Tsuruo; Tetsuichiro Muto
Role of p53 and p21/WAF1 detection in patient selection for preoperative radiotherapy in rectal cancer patients.
Diseases of the colon and rectum 1998;41(1):68-74.
1997: Tetsuichiro Muto; Hirokazu Nagawa; Tomomi Watanabe; Tadahiko Masaki; Toshio Sawada
Colorectal carcinogenesis: historical review.
Diseases of the colon and rectum 1997;40(10 Suppl):S80-5.
1997: O Tominaga; Marcelo Eidi Nita; Hirokazu Nagawa; S Fujii; Takashi Tsuruo; Tetsuichiro Muto
Expressions of cell cycle regulators in human colorectal cancer cell lines.
Japanese journal of cancer research : Gann 1997;88(9):855-60.
1997: Hirokazu Nagawa; Yasuyuki Seto; O Kobori; Tetsuichiro Muto
An experience of treatment for patients with thoracic esophageal cancer invading adjacent organs.
Japanese journal of clinical oncology 1997;27(4):248-50.
1997: Y Seto; Hirokazu Nagawa; Tetsuichiro Muto
Results of extended lymph node dissection for gastric cancer cases with N2 lymph node metastasis.
International surgery 1997;82(3):257-61.
1997: Yasuyuki Seto; Hirokazu Nagawa; Tetsuichiro Muto
Intra-operative diagnosis of N2 lymph node metastasis of gastric cancer.
Hepato-gastroenterology 1997;44(15):838-41.
1997: Yasuyuki Seto; Hirokazu Nagawa; Tetsuichiro Muto
Prognostic significance of non-gastric malignancy after treatment of early gastric cancer.
The British journal of surgery 1997;84(3):418-21.
1997: Hirokazu Nagawa; Yasuyuki Seto; Takashi Nakatsuka; Shoichi Kaizaki; Tetsuichiro Muto
Microvascular anastomosis for additional blood flow in reconstruction after intrathoracic esophageal carcinoma surgery.
American journal of surgery 1997;173(2):131-3.
1997: Yasuyuki Seto; Hirokazu Nagawa; Tetsuichiro Muto
Impact of lymph node metastasis on survival with early gastric cancer.
World journal of surgery 1997;21(2):186-89; discussion 190.
1997: W S Tsai; Hirokazu Nagawa; Tetsuichiro Muto
Differential effects of polyunsaturated fatty acids on chemosensitivity of NIH3T3 cells and its transformants.
International journal of cancer. Journal international du cancer 1997;70(3):357-61.
1996: Chuan-gang Fu; Tetsuichiro Muto; T Masaki; Hirokazu Nagawa
Zonal adult Hirschsprung's disease.
Gut 1996;39(5):765-7.
1996: Yasuyuki Seto; Hirokazu Nagawa; Tetsuichiro Muto
Treatment of multiple early gastric cancer.
Japanese journal of clinical oncology 1996;26(3):134-8.
1995: Hirokazu Nagawa; S Yamagata; Tetsuichiro Muto
[Precancerous lesion in colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1995;22(14):2043-7.
1995: Hirokazu Nagawa; Shoichi Kaizaki; Yasuyuki Seto; O Tominaga; Tetsuichiro Muto
The relationship of macroscopic shape of superficial esophageal carcinoma to depth of invasion and regional lymph node metastasis.
Cancer 1995;75(5):1061-4.
1994: Hirokazu Nagawa; Tetsuichiro Muto
[Cancer of the small intestine].
Nihon rinsho. Japanese journal of clinical medicine 1994;Suppl 6():231-3.
1994: Joji Kitayama; Hirokazu Nagawa; H Yasuhara; Nelson H Tsuno; W Kimura; Y Shibata; T Muto
Suppressive effect of basic fibroblast growth factor on transendothelial emigration of CD4(+) T-lymphocyte.
Cancer research 1994;54(17):4729-33.
1994: Hirokazu Nagawa; O Kobori; Tetsuichiro Muto
Prediction of pulmonary complications after transthoracic oesophagectomy.
The British journal of surgery 1994;81(6):860-2.
1994: Joji Kitayama; Nelson H Tsuno; H Yasuhara; Hirokazu Nagawa; W Kimura; A Kuroda; Yoichi Shibata; Takeo Juji; Tetsuichiro Muto
Lysis of endothelial cells by autologous lymphokine-activated killer cells.
Cancer immunology, immunotherapy : CII 1994;38(5):317-22.
1994: T Sano; O Kobori; Hirokazu Nagawa; Tetsuichiro Muto
The macroscopic diagnosis of lymph node metastasis from early gastric cancer.
Surgery today 1994;24(1):37-9.
1994: Hirokazu Nagawa; Tetsuichiro Muto
[Cancer of the small intestine].
Ryōikibetsu shōkōgun shirīzu 1994;(6):231-3.
1993: Hirokazu Nagawa; Nelson H Tsuno; H Saito; Tetsuichiro Muto
Ileal obstruction due to metastatic liposarcoma: a case report.
Gastroenterologia Japonica 1993;28(5):706-11.
1993: Joji Kitayama; Y Atomi; Hirokazu Nagawa; A Kuroda; T Mutoh; M Minami; Takeo Juji
Functional analysis of TCR gamma delta+ T cells in tumour-infiltrating lymphocytes (TIL) of human pancreatic cancer.
Clinical and experimental immunology 1993;93(3):442-7.
1993: T Sano; O Kobori; S Kuroki; Hirokazu Nagawa; Tetsuichiro Muto
Effect of experimental hypochlorhydria on the histological differentiation of adenocarcinomas in the canine stomach.
Japanese journal of cancer research : Gann 1993;84(5):495-500.
1993: Nelson H Tsuno; Tetsuichiro Muto; Yoshinobu Kubota; T Sawada; Hirokazu Nagawa
Morphometric analysis of colonic adenomatous polyps.
Japanese journal of cancer research : Gann 1993;84(3):310-4.