FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Kjell Någren

Research Profile

Chemicals & Drugs

Procedures

Anatomy

Disorders

Alzheimer's Disease

Concepts & Ideas

Co-author Network

Publications

TOP 3
L Tuominen; J Viikari; C R Cloninger; Jarmo Hietala; Jussi Hirvonen; E Isometsä; P Laine; T Melartin; Kjell Någren; O Raitakari; J Salo; L Keltikangas-Järvinen
Temperament, character and serotonin activity in the human brain: a positron emission tomography study based on a general population cohort.
Anne Roivainen; Johanna Virtanen; Markku Kallajoki; Harry Kujari; Rauli Leino; Kjell Någren; Alexandru Naum; Heimo Nurmi; Heikki Nuutinen; Jari Ovaska; Riitta Parkkola; Peter Roberts; Marko Seppänen
Characterization of hepatic tumors using [11C]metomidate through positron emission tomography: comparison with [11C]acetate.
Agneta Nordberg; Aren Okello; Daniela Perani; Juha Rinne; Noora Scheinin; Koen Van Laere; Rik Vandenberghe; Mathieu Vandenbulcke; Ove Almkvist; David J Brooks; Stephen F Carter; Alexander Drzezga; Paul Edison; Anton Forsberg; Valentina Garibotto; Timo Grimmer; Rainer Hinz; Elke Kalbe; Mira Karrasch; Bengt Långström; Isabelle Miederer; Kjell Någren; Natalie Nelissen; Karl Herholz
A European multicentre PET study of fibrillar amyloid in Alzheimer's disease.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Kjell Någren (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: L Tuominen; J Viikari; C R Cloninger; Jarmo Hietala; Jussi Hirvonen; E Isometsä; P Laine; T Melartin; Kjell Någren; O Raitakari; J Salo; L Keltikangas-Järvinen
Temperament, character and serotonin activity in the human brain: a positron emission tomography study based on a general population cohort.
Psychological medicine 2013;43(4):881-94.
2013: Anne Roivainen; Johanna Virtanen; Markku Kallajoki; Harry Kujari; Rauli Leino; Kjell Någren; Alexandru Naum; Heimo Nurmi; Heikki Nuutinen; Jari Ovaska; Riitta Parkkola; Peter Roberts; Marko Seppänen
Characterization of hepatic tumors using [11C]metomidate through positron emission tomography: comparison with [11C]acetate.
EJNMMI research 2013;3(1):13.
2013: Agneta Nordberg; Aren Okello; Daniela Perani; Juha Rinne; Noora Scheinin; Koen Van Laere; Rik Vandenberghe; Mathieu Vandenbulcke; Ove Almkvist; David J Brooks; Stephen F Carter; Alexander Drzezga; Paul Edison; Anton Forsberg; Valentina Garibotto; Timo Grimmer; Rainer Hinz; Elke Kalbe; Mira Karrasch; Bengt Långström; Isabelle Miederer; Kjell Någren; Natalie Nelissen; Karl Herholz
A European multicentre PET study of fibrillar amyloid in Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2013;40(1):104-14.
2013: Lisa Mosconi; John Murray; Kjell Någren; Elizabeth Pirraglia; Juha O Rinne; Noora Scheinin; Wai Hon Tsui; Shankar Vallabhajosula; Tapio Viljanen; Schantel Williams; Lidia Glodzik; Stanley J Goldsmith; Yi Li; Pauline McHugh; Megan Cummings; Mony J de Leon
Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents.
Neurobiology of aging 2013;34(1):22-34.
2012: Marco Bucci; Manuela Cabiati; Silvia Del Ry; Ronald Borra; Juhani Knuuti; Romina Maggio; Kjell Någren; Pirjo Nuutila; Lionel H Opie; Uberto Pagotto; Jussi P Pärkkä; Riitta Parkkola; Sara Rigazio; Markku Taittonen; Helena Tuunanen; Tapio Viljanen; Patricia Iozzo
Trimetazidine reduces endogenous free fatty acid oxidation and improves myocardial efficiency in obese humans.
Cardiovascular therapeutics 2012;30(6):333-41.
2012: Nora Hagelberg; Jarmo Hietala; Sargo Aalto; Kjell Någren; Antti Pertovaara; Ullamari Pesonen; Harry Scheinin; Lauri Tuominen; Ilkka K Martikainen
Striatal μ-opioid receptor availability predicts cold pressor pain threshold in healthy human subjects.
Neuroscience letters 2012;521(1):11-4.
2012: Lauri Tuominen; Jorma Viikari; Jussi Hirvonen; Erkki Isometsä; Liisa Keltikangas-Järvinen; Pauliina Laine; Tarja Melartin; Kjell Någren; Olli Raitakari; Johanna Salo; Jarmo Hietala
Temperament trait Harm Avoidance associates with μ-opioid receptor availability in frontal cortex: a PET study using [(11)C]carfentanil.
NeuroImage 2012;61(3):670-6.
2012: Jussi Koivunen; Kjell Någren; Sargo Aalto; Semi Helin; Mira Karrasch; Noora M Scheinin; Tero Vahlberg; Matti Viitanen; Juha O Rinne
Cognitive decline and amyloid accumulation in patients with mild cognitive impairment.
Dementia and geriatric cognitive disorders 2012;34(1):31-7.
2011: Jussi Hirvonen; Jaana Kajander; Sargo Aalto; Jarmo Hietala; Juha Markkula; Kjell Någren; Helena Rasi-Hakala; Jouko K Salminen; Hasse Karlsson
Effects of antidepressant drug treatment and psychotherapy on striatal and thalamic dopamine D2/3 receptors in major depressive disorder studied with [11C]raclopride PET.
Journal of psychopharmacology (Oxford, England) 2011;25(10):1329-36.
2011: Marco Bucci; Silvia Del Ry; Daniela Giannessi; Ronald Borra; Juhani Knuuti; Romina Maggio; Kjell Någren; Pirjo Nuutila; Vesa Oikonen; Riitta Parkkola; Sara Rigazio; Markku Taittonen; Helena Tuunanen; Tapio Viljanen; Patricia Iozzo
Human obesity is characterized by defective fat storage and enhanced muscle fatty acid oxidation, and trimetazidine gradually counteracts these abnormalities.
American journal of physiology. Endocrinology and metabolism 2011;301(1):E105-12.
2011: Eduard Maron; Kjell Någren; David J Nutt; Jakov Shlik; Jari Tiihonen; Innar Tõru; Lauri Tuominen; Veiko Vasar; Semi Helin; Jussi Hirvonen; Ville Lumme; Jarmo Hietala
Gender differences in brain serotonin transporter availability in panic disorder.
Journal of psychopharmacology (Oxford, England) 2011;25(7):952-9.
2011: A Östberg; J Virta; Juha O Rinne; Vesa Oikonen; P Luoto; Kjell Någren; E Arponen; Olli Tenovuo
Cholinergic dysfunction after traumatic brain injury: preliminary findings from a PET study.
Neurology 2011;76(12):1046-50.
2011: J Koivunen; N Scheinin; J R Virta; Sargo Aalto; T Vahlberg; Kjell Någren; Semi Helin; Riitta Parkkola; Matti Viitanen; Juha O Rinne
Amyloid PET imaging in patients with mild cognitive impairment: a 2-year follow-up study.
Neurology 2011;76(12):1085-90.
2011: Kati Alakurtti; Sargo Aalto; Jarkko J Johansson; Kjell Någren; Terhi Tuokkola; Vesa Oikonen; Matti Laine; Juha O Rinne
Reproducibility of striatal and thalamic dopamine D2 receptor binding using [11C]raclopride with high-resolution positron emission tomography.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(1):155-65.
2010: Chiara Felicini; Kjell Någren; Andrea Berton; Giancarlo Pascali; Piero A Salvadori
Development of an automated modular system for the synthesis of [11C]acetate.
Nuclear medicine communications 2010;31(12):1033-9.
2010: Pekka Jokinen; Noora Scheinin; Sargo Aalto; Kjell Någren; Nina Savisto; Riitta Parkkola; Johanna Rokka; Merja Haaparanta; Matias Röyttä; Juha O Rinne
[(11)C]PIB-, [(18)F]FDG-PET and MRI imaging in patients with Parkinson's disease with and without dementia.
Parkinsonism & related disorders 2010;16(10):666-70.
2010: Anders Ettrup; Mikael Palner; Nic Gillings; Martin A Santini; Martin Hansen; Birgitte Kornum; Lars K Rasmussen; Kjell Någren; Jacob Madsen; Mikael Begtrup; Gitte Moos Knudsen
Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(11):1763-70.
2010: Veronica Fagerholm; Kirsi K Mikkola; Tamiko Ishizu; Eveliina Arponen; Saila Kauhanen; Kjell Någren; Olof Solin; Pirjo Nuutila; Merja Haaparanta
Assessment of islet specificity of dihydrotetrabenazine radiotracer binding in rat pancreas and human pancreas.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(9):1439-46.
2010: Patricia Iozzo; Marco Bucci; Anne Roivainen; Kjell Någren; Mikko J Järvisalo; Jan Kiss; Letizia Guiducci; Barbara Fielding; Alexandru Naum; Ronald Borra; Kirsi Virtanen; Timo Savunen; Piero A Salvadori; Ele Ferrannini; Juhani Knuuti; Pirjo Nuutila
Fatty acid metabolism in the liver, measured by positron emission tomography, is increased in obese individuals.
Gastroenterology 2010;139(3):846-56, 856.e1-6.
2010: Anna Karmi; Patricia Iozzo; Antti Viljanen; Jussi Hirvonen; Barbara A Fielding; Kirsi Virtanen; Vesa Oikonen; Jukka Kemppainen; Tapio Viljanen; Letizia Guiducci; Merja Haaparanta-Solin; Kjell Någren; Olof Solin; Pirjo Nuutila
Increased brain fatty acid uptake in metabolic syndrome.
Diabetes 2010;59(9):2171-7.
2010: Kjell Någren; Christer Halldin; Juha O Rinne
Radiopharmaceuticals for positron emission tomography investigations of Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2010;37(8):1575-93.
2010: Pauliina Luoto; Iina Laitinen; Sami Suilamo; Kjell Någren; Anne Roivainen
Human dosimetry of carbon-11 labeled N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide extrapolated from whole-body distribution kinetics and radiometabolism in rats.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2010;12(4):435-42.
2010: Ville Lumme; Mika M Hirvonen; Tuula Ilonen; Jussi Hirvonen; Kjell Någren; Jarmo Hietala
Cortical dopamine D2/D3 receptors and verbal memory in man.
NeuroImage 2010;51(2):918-22.
2010: Iina E K Laitinen; Pauliina Luoto; Kjell Någren; Päivi M Marjamäki; Johanna M U Silvola; Sanna Hellberg; V Jukka O Laine; Seppo Ylä-Herttuala; Juhani Knuuti; Anne Roivainen
Uptake of 11C-choline in mouse atherosclerotic plaques.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(5):798-802.
2010: Mika M Hirvonen; Kjell Någren; Juha O Rinne; Ullamari Pesonen; Tero Vahlberg; Nora Hagelberg; Jarmo Hietala
COMT Val158Met genotype does not alter cortical or striatal dopamine D2 receptor availability in vivo.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2010;12(2):192-7.
2010: Lisa Mosconi; Juha O Rinne; Wai H Tsui; Valentina Berti; Yi Li; Huiyu Wang; John Murray; Noora Scheinin; Kjell Någren; Schantel Williams; Lidia Glodzik; Susan De Santi; Shankar Vallabhajosula; Mony J de Leon
Increased fibrillar amyloid-{beta} burden in normal individuals with a family history of late-onset Alzheimer's.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(13):5949-54.
2010: Hasse Karlsson; Jussi Hirvonen; Jaana Kajander; Juha Markkula; H Rasi-Hakala; Jouko K Salminen; Kjell Någren; Sargo Aalto; Jarmo Hietala
Research letter: Psychotherapy increases brain serotonin 5-HT1A receptors in patients with major depressive disorder.
Psychological medicine 2010;40(3):523-8.
2010: Jussi Hirvonen; Anne Roivainen; Jere Virta; Semi Helin; Kjell Någren; Juha O Rinne
Human biodistribution and radiation dosimetry of 11C-(R)-PK11195, the prototypic PET ligand to image inflammation.
European journal of nuclear medicine and molecular imaging 2010;37(3):606-12.
2010: Koen Van Laere; Andrea Varrone; Jan Booij; Thierry Vander Borght; Flavio Nobili; Ozlem L Kapucu; Zuzana Walker; Kjell Någren; Klaus Tatsch; Jacques Darcourt
EANM procedure guidelines for brain neurotransmission SPECT/PET using dopamine D2 receptor ligands, version 2.
European journal of nuclear medicine and molecular imaging 2010;37(2):434-42.
2010: Jacques Darcourt; Jan Booij; Klaus Tatsch; Andrea Varrone; Thierry Vander Borght; Ozlem L Kapucu; Kjell Någren; Flavio Nobili; Zuzana Walker; Koen Van Laere
EANM procedure guidelines for brain neurotransmission SPECT using (123)I-labelled dopamine transporter ligands, version 2.
European journal of nuclear medicine and molecular imaging 2010;37(2):443-50.
2010: Juha O Rinne; Kjell Någren
Positron emission tomography in at risk patients and in the progression of mild cognitive impairment to Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;19(1):291-300.
2009: Andrea Varrone; Susanne Asenbaum; Thierry Vander Borght; Jan Booij; Flavio Nobili; Kjell Någren; Jacques Darcourt; Ozlem L Kapucu; Klaus Tatsch; Peter Bartenstein; Koen Van Laere
EANM procedure guidelines for PET brain imaging using [18F]FDG, version 2.
European journal of nuclear medicine and molecular imaging 2009;36(12):2103-10.
2009: Ozlem L Kapucu; Flavio Nobili; Andrea Varrone; Jan Booij; Thierry Vander Borght; Kjell Någren; Jacques Darcourt; Klaus Tatsch; Koen Van Laere
EANM procedure guideline for brain perfusion SPECT using 99mTc-labelled radiopharmaceuticals, version 2.
European journal of nuclear medicine and molecular imaging 2009;36(12):2093-102.
2009: Harry Vilkman; Jaana Kajander; Sargo Aalto; Tero Vahlberg; Kjell Någren; Topias Allonen; Erkka Syvälahti; Jarmo Hietala
The effects of lorazepam on extrastriatal dopamine D(2/3)-receptors-A double-blind randomized placebo-controlled PET study.
Psychiatry research 2009;174(2):130-7.
2009: N M Scheinin; Sargo Aalto; J Koikkalainen; J Lötjönen; Mira Karrasch; N Kemppainen; M Viitanen; Kjell Någren; S Helin; Mika Scheinin; J O Rinne
Follow-up of [11C]PIB uptake and brain volume in patients with Alzheimer disease and controls.
Neurology 2009;73(15):1186-92.
2009: Mika M Hirvonen; Aki Laakso; Kjell Någren; Juha O Rinne; Tiina Pohjalainen; Jarmo Hietala
C957T polymorphism of dopamine D2 receptor gene affects striatal DRD2 in vivo availability by changing the receptor affinity.
Synapse (New York, N.Y.) 2009;63(10):907-12.
2009: Sargo Aalto; Noora M Scheinin; Nina M Kemppainen; Kjell Någren; Marita Kailajärvi; Mika Leinonen; Mika Scheinin; Juha O Rinne
Reproducibility of automated simplified voxel-based analysis of PET amyloid ligand [11C]PIB uptake using 30-min scanning data.
European journal of nuclear medicine and molecular imaging 2009;36(10):1651-60.
2009: Ilkka K Martikainen; Jussi Hirvonen; Ullamari Pesonen; Nora Hagelberg; Heikki Laurikainen; Heikki Tuikkala; Jaana Kajander; Kjell Någren; Jarmo Hietala; Antti Pertovaara
Differential associations between brain 5-HT(1A) receptor binding and response to pain versus touch.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(7):821-30.
2009: Mika M Hirvonen; Ville Lumme; Jussi Hirvonen; Ullamari Pesonen; Kjell Någren; Tero Vahlberg; Harry Scheinin; Jarmo Hietala
C957T polymorphism of the human dopamine D2 receptor gene predicts extrastriatal dopamine receptor availability in vivo.
Progress in neuro-psychopharmacology & biological psychiatry 2009;33(4):630-6.
2009: J Hirvonen; Marita E H Kailajärvi; T Haltia; S Koskimies; Kjell Någren; P Virsu; Vesa Oikonen; Hannu Sipilä; P Ruokoniemi; K Virtanen; Mika Scheinin; Juha O Rinne
Assessment of MAO-B occupancy in the brain with PET and [11C]-L-deprenyl-D2: a dose-finding study with a novel MAO-B inhibitor, EVT 301.
Clinical pharmacology and therapeutics 2009;85(5):506-12.
2009: Anne Roivainen; Kjell Någren; Jussi Hirvonen; Vesa Oikonen; Pauliina Virsu; Tuula Tolvanen; Juha O Rinne
Whole-body distribution and metabolism of [N-methyl-11C](R)-1-(2-chlorophenyl)-N-(1-methylpropyl)-3-isoquinolinecarboxamide in humans; an imaging agent for in vivo assessment of peripheral benzodiazepine receptor activity with positron emission tomography.
European journal of nuclear medicine and molecular imaging 2009;36(4):671-82.
2009: Sargo Aalto; Jussi Hirvonen; Valtteri Kaasinen; Nora Hagelberg; Jaana Kajander; Kjell Någren; Timo Seppälä; Juha O Rinne; Harry Scheinin; Jarmo Hietala
The effects of d-amphetamine on extrastriatal dopamine D2/D3 receptors: a randomized, double-blind, placebo-controlled PET study with [11C]FLB 457 in healthy subjects.
European journal of nuclear medicine and molecular imaging 2009;36(3):475-83.
2009: Jussi Hirvonen; Sargo Aalto; Nora Hagelberg; Anu Maksimow; Kimmo Ingman; Vesa Oikonen; Jussi Virkkala; Kjell Någren; Harry Scheinin
Measurement of central mu-opioid receptor binding in vivo with PET and [11C]carfentanil: a test-retest study in healthy subjects.
European journal of nuclear medicine and molecular imaging 2009;36(2):275-86.
2009: Paula Lindholm; M Lapela; Kjell Någren; Pertti Lehikoinen; Heikki Minn; Sirkku Jyrkkiö
Preliminary study of carbon-11 methionine PET in the evaluation of early response to therapy in advanced breast cancer.
Nuclear medicine communications 2009;30(1):30-6.
2009: Iina Laitinen; Päivi Marjamäki; Kjell Någren; Jukka Laine; Ian Wilson; Pia Leppänen; Seppo Ylä-Herttuala; Anne Roivainen; Juhani Knuuti
Uptake of inflammatory cell marker [11C]PK11195 into mouse atherosclerotic plaques.
European journal of nuclear medicine and molecular imaging 2009;36(1):73-80.
2008: Olli Tenovuo; Nina Kemppainen; Sargo Aalto; Kjell Någren; Juha O Rinne
Posterior cortical atrophy: a rare form of dementia with in vivo evidence of amyloid-beta accumulation.
Journal of Alzheimer's disease : JAD 2008;15(3):351-5.
2008: Ilkka Heinonen; Sergey Nesterov; Kaisa Liukko; Jukka Kemppainen; Kjell Någren; Matti Luotolahti; Pauliina Virsu; Vesa Oikonen; Pirjo Nuutila; Urho M Kujala; Heikki Kainulainen; Robert Boushel; Juhani Knuuti; Kari K Kalliokoski
Myocardial blood flow and adenosine A2A receptor density in endurance athletes and untrained men.
The Journal of physiology 2008;586(Pt 21):5193-202.
2008: Ville Leinonen; Irina Alafuzoff; Sargo Aalto; Timo Suotunen; S Savolainen; Kjell Någren; Tero Tapiola; Tuula Pirttilä; Jaakko Rinne; Juha E Jääskeläinen; Hilkka Soininen; Juha O Rinne
Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh Compound B.
Archives of neurology 2008;65(10):1304-9.
2008: Helena Tuunanen; Erik Engblom; Alexandru Naum; Kjell Någren; Mika Scheinin; Birger Hesse; K E Juhani Airaksinen; Pirjo Nuutila; Patricia Iozzo; Heikki Ukkonen; Lionel Henry Opie; Juhani Knuuti
Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy.
Circulation 2008;118(12):1250-8.
2008: Lauri T Haltia; Juha O Rinne; Semi Helin; Riitta Parkkola; Kjell Någren; Valtteri Kaasinen
Effects of intravenous placebo with glucose expectation on human basal ganglia dopaminergic function.
Synapse (New York, N.Y.) 2008;62(9):682-8.
2008: Sara Rigazio; Hanna-Riikka Lehto; Helena Tuunanen; Kjell Någren; Mikko Kankaanpaa; Claudia Simi; Ronald Borra; Alexandru G Naum; Riitta Parkkola; Juhani Knuuti; Pirjo Nuutila; Patricia Iozzo
The lowering of hepatic fatty acid uptake improves liver function and insulin sensitivity without affecting hepatic fat content in humans.
American journal of physiology. Endocrinology and metabolism 2008;295(2):E413-9.
2008: Jussi Koivunen; A Verkkoniemi; Sargo Aalto; A Paetau; J-P Ahonen; Matti Viitanen; Kjell Någren; J Rokka; Merja Haaparanta; Hannu Kalimo; Juha O Rinne
PET amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease.
Brain : a journal of neurology 2008;131(Pt 7):1845-53.
2008: Elina Salmi; Sargo Aalto; Jussi Hirvonen; Jaakko W Långsjö; Anu Maksimow; Vesa Oikonen; Liisa Metsähonkala; Jussi Virkkala; Kjell Någren; Harry Scheinin
Measurement of GABAA receptor binding in vivo with [11C]flumazenil: a test-retest study in healthy subjects.
NeuroImage 2008;41(2):260-9.
2008: Jussi Hirvonen; Hasse Karlsson; Jaana Kajander; Antti Lepola; Juha Markkula; Helena Rasi-Hakala; Kjell Någren; Jouko K Salminen; Jarmo Hietala
Decreased brain serotonin 5-HT1A receptor availability in medication-naive patients with major depressive disorder: an in-vivo imaging study using PET and [carbonyl-11C]WAY-100635.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2008;11(4):465-76.
2008: Teemu Kalliokoski; Pirjo Nuutila; Kirsi A Virtanen; Patricia Iozzo; Marco Bucci; Erkki Svedström; Anne Roivainen; Kjell Någren; Tapio Viljanen; Heikki Minn; Juhani Knuuti; Tapani Rönnemaa; Olli Simell
Pancreatic glucose uptake in vivo in men with newly diagnosed type 1 diabetes.
The Journal of clinical endocrinology and metabolism 2008;93(5):1909-14.
2008: Jussi Hirvonen; Hasse Karlsson; Jaana Kajander; Juha Markkula; Helena Rasi-Hakala; Kjell Någren; Jouko K Salminen; Jarmo Hietala
Striatal dopamine D2 receptors in medication-naive patients with major depressive disorder as assessed with [11C]raclopride PET.
Psychopharmacology 2008;197(4):581-90.
2008: Jussi Hirvonen; Jarkko Johansson; Mika Teräs; Vesa Oikonen; Ville Lumme; Pauliina Virsu; Anne Roivainen; Kjell Någren; Christer Halldin; Lars Farde; Jarmo Hietala
Measurement of striatal and extrastriatal dopamine transporter binding with high-resolution PET and [11C]PE2I: quantitative modeling and test-retest reproducibility.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(5):1059-69.
2008: Anne M Remes; Lauri Laru; Hannu Tuominen; Sargo Aalto; Nina Kemppainen; H Mononen; Kjell Någren; Riitta Parkkola; Juha O Rinne
Carbon 11-labeled pittsburgh compound B positron emission tomographic amyloid imaging in patients with APP locus duplication.
Archives of neurology 2008;65(4):540-4.
2008: Jere R Virta; Tuula Tolvanen; Kjell Någren; Anna Brück; Anne Roivainen; Juha O Rinne
1-11C-methyl-4-piperidinyl-N-butyrate radiation dosimetry in humans by dynamic organ-specific evaluation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(3):347-53.
2008: Jussi Koivunen; T Pirttilä; Nina Kemppainen; S Aalto; S-K Herukka; A M Jauhianen; T Hänninen; M Hallikainen; Kjell Någren; Juha O Rinne; Hilkka Soininen
PET amyloid ligand [11C]PIB uptake and cerebrospinal fluid beta-amyloid in mild cognitive impairment.
Dementia and geriatric cognitive disorders 2008;26(4):378-83.
2008: Elina Salmi; Ruut M Laitio; Sargo Aalto; Anu Maksimow; Jaakko W Långsjö; Kaike K Kaisti; Riku Aantaa; Vesa Oikonen; Liisa Metsähonkala; Kjell Någren; Esa R Korpi; Harry Scheinin
Xenon does not affect gamma-aminobutyric acid type A receptor binding in humans.
Anesthesia and analgesia 2008;106(1):129-34, table of contents.
2008: Nina Kemppainen; Sargo Aalto; Mira Karrasch; Kjell Någren; Nina Savisto; Vesa Oikonen; Matti Viitanen; Riitta Parkkola; Juha O Rinne
Cognitive reserve hypothesis: Pittsburgh Compound B and fluorodeoxyglucose positron emission tomography in relation to education in mild Alzheimer's disease.
Annals of neurology 2008;63(1):112-8.
2007: Ville Lumme; Sargo Aalto; Tuula Ilonen; Kjell Någren; Jarmo Hietala
Dopamine D2/D3 receptor binding in the anterior cingulate cortex and executive functioning.
Psychiatry research 2007;156(1):69-74.
2007: Ilkka K Martikainen; Jussi Hirvonen; Jaana Kajander; Nora Hagelberg; Heikki Mansikka; Kjell Någren; Jarmo Hietala; Antti Pertovaara
Correlation of human cold pressor pain responses with 5-HT(1A) receptor binding in the brain.
Brain research 2007;1172():21-31.
2007: Lauri T Haltia; Juha O Rinne; Harri Merisaari; Ralph P Maguire; Eriika Savontaus; Semi Helin; Kjell Någren; Valtteri Kaasinen
Effects of intravenous glucose on dopaminergic function in the human brain in vivo.
Synapse (New York, N.Y.) 2007;61(9):748-56.
2007: Miikka Korja; Valtteri Kaasinen; Salla Lamusuo; Riitta Parkkola; Kjell Någren; Reijo J Marttila
Substantial thalamostriatal dopaminergic defect in Unverricht-Lundborg disease.
Epilepsia 2007;48(9):1768-73.
2007: Nina Kemppainen; Sargo Aalto; Ian wilson; Kjell Någren; Semi Helin; Anna Brück; Vesa Oikonen; Marita E H Kailajärvi; Mika Scheinin; Matti Viitanen; Riitta Parkkola; Juha O Rinne
PET amyloid ligand [11C]PIB uptake is increased in mild cognitive impairment.
Neurology 2007;68(19):1603-6.
2007: Jarna C Hannukainen; Tuula Janatuinen; Jyri O Toikka; Mikko J Järvisalo; Olli Heinonen; Jukka Kapanen; Kjell Någren; Pirjo Nuutila; Urho M Kujala; Jaakko Kaprio; Juhani Knuuti; Kari K Kalliokoski
Myocardial and peripheral vascular functional adaptation to exercise training.
Scandinavian journal of medicine & science in sports 2007;17(2):139-47.
2007: Noora M Scheinin; Tuula Tolvanen; Ian wilson; Eveliina M Arponen; Kjell Någren; Juha O Rinne
Biodistribution and radiation dosimetry of the amyloid imaging agent 11C-PIB in humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(1):128-33.
2007: Jussi Hirvonen; Jaana Kajander; Topias Allonen; Vesa Oikonen; Kjell Någren; Jarmo Hietala
Measurement of serotonin 5-HT1A receptor binding using positron emission tomography and [carbonyl-(11)C]WAY-100635-considerations on the validity of cerebellum as a reference region.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(1):185-95.
2006: Helena Tuunanen; Erik Engblom; Alexandru Naum; Kjell Någren; Birger Hesse; K E Juhani Airaksinen; Pirjo Nuutila; Patricia Iozzo; Heikki Ukkonen; Lionel Henry Opie; Juhani Knuuti
Free fatty acid depletion acutely decreases cardiac work and efficiency in cardiomyopathic heart failure.
Circulation 2006;114(20):2130-7.
2006: Nina Kemppainen; Sargo Aalto; Ian wilson; Kjell Någren; Semi Helin; Anna Brück; Vesa Oikonen; Marita E H Kailajärvi; Mika Scheinin; Matti Viitanen; Riitta Parkkola; Juha O Rinne
Voxel-based analysis of PET amyloid ligand [11C]PIB uptake in Alzheimer disease.
Neurology 2006;67(9):1575-80.
2006: Helena Tuunanen; Erik Engblom; Alexandru Naum; Mika Scheinin; Kjell Någren; Juhani Airaksinen; Pirjo Nuutila; Patricia Iozzo; Heikki Ukkonen; Juhani Knuuti
Decreased myocardial free fatty acid uptake in patients with idiopathic dilated cardiomyopathy: evidence of relationship with insulin resistance and left ventricular dysfunction.
Journal of cardiac failure 2006;12(8):644-52.
2006: Jussi Hirvonen; Theo G M van Erp; Jukka Huttunen; Sargo Aalto; Kjell Någren; Matti O Huttunen; Jouko Lönnqvist; Jaakko Kaprio; Tyrone D Cannon; Jarmo Hietala
Brain dopamine d1 receptors in twins discordant for schizophrenia.
The American journal of psychiatry 2006;163(10):1747-53.
2006: Tuula Tolvanen; Kjell Någren; Meixiang Yu; Eija Sutinen; Katja Havu-Aurén; Sirkku Jyrkkiö; Markku R Asola; Eira Kotoneva; Pirjo Nuutila; Heikki Minn
Human radiation dosimetry of [11C]MeAIB, a new tracer for imaging of system A amino acid transport.
European journal of nuclear medicine and molecular imaging 2006;33(10):1178-84.
2006: Letizia Guiducci; Mikko J Järvisalo; Jan Kiss; Kjell Någren; Antti Viljanen; Alexandru Naum; Amalia Gastaldelli; Timo Savunen; Juhani Knuuti; Piero A Salvadori; Ele Ferrannini; Pirjo Nuutila; Patricia Iozzo
[11C]palmitate kinetics across the splanchnic bed in arterial, portal and hepatic venous plasma during fasting and euglycemic hyperinsulinemia.
Nuclear medicine and biology 2006;33(4):521-8.
2006: Jussi Hirvonen; Theo G M van Erp; Jukka Huttunen; Kjell Någren; Matti O Huttunen; Sargo Aalto; Jouko Lönnqvist; Jaakko Kaprio; Tyrone D Cannon; Jarmo Hietala
Striatal dopamine D1 and D2 receptor balance in twins at increased genetic risk for schizophrenia.
Psychiatry research 2006;146(1):13-20.
2005: Kimmo Ingman; Nora Hagelberg; Sargo Aalto; Kjell Någren; Auni Juhakoski; Sakari Karhuvaara; Antero Kallio; Vesa Oikonen; Jarmo Hietala; Harry Scheinin
Prolonged central mu-opioid receptor occupancy after single and repeated nalmefene dosing.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(12):2245-53.
2005: Sargo Aalto; Jouni A Ihalainen; Jussi Hirvonen; Jaana Kajander; Harry Scheinin; Heikki Tanila; Kjell Någren; Harry Vilkman; Lars ´Gustafsson; Erkka Syvälahti; Jarmo Hietala
Cortical glutamate-dopamine interaction and ketamine-induced psychotic symptoms in man.
Psychopharmacology 2005;182(3):375-83.
2005: Elina Salmi; Jaakko W Långsjö; Sargo Aalto; Kjell Någren; Liisa Metsähonkala; Kaike K Kaisti; Esa R Korpi; Jarmo Hietala; Harry Scheinin
Subanesthetic ketamine does not affect 11C-flumazenil binding in humans.
Anesthesia and analgesia 2005;101(3):722-5, table of contents.
2005: Jussi Hirvonen; Theo G M van Erp; Jukka Huttunen; Sargo Aalto; Kjell Någren; Matti O Huttunen; Jouko Lönnqvist; Jaakko Kaprio; Jarmo Hietala; Tyrone D Cannon
Increased caudate dopamine D2 receptor availability as a genetic marker for schizophrenia.
Archives of general psychiatry 2005;62(4):371-8.
2005: Ilkka K Martikainen; Nora Hagelberg; Heikki Mansikka; Jarmo Hietala; Kjell Någren; Harry Scheinin; Antti Pertovaara
Association of striatal dopamine D2/D3 receptor binding potential with pain but not tactile sensitivity or placebo analgesia.
Neuroscience letters 2005;376(3):149-53.
2005: Sargo Aalto; Anna Brück; Matti Laine; Kjell Någren; Juha O Rinne
Frontal and temporal dopamine release during working memory and attention tasks in healthy humans: a positron emission tomography study using the high-affinity dopamine D2 receptor ligand [11C]FLB 457.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(10):2471-7.
2004: Anne Roivainen; Juha Rinne; Jere Virta; Tarja Järvenpää; Satu Salomäki; Miexiang Yu; Kjell Någren
Biodistribution and blood metabolism of 1-11C-methyl-4-piperidinyl n-butyrate in humans: an imaging agent for in vivo assessment of butyrylcholinesterase activity with PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(12):2032-9.
2004: Jani Penttilä; Jaana Kajander; Sargo Aalto; Jussi Hirvonen; Kjell Någren; Tuula Ilonen; Erkka Syvälahti; Jarmo Hietala
Effects of fluoxetine on dopamine D2 receptors in the human brain: a positron emission tomography study with [11C]raclopride.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2004;7(4):431-9.
2004: M Hirvonen; Aki Laakso; Kjell Någren; Juha O Rinne; Tiina Pohjalainen; Jarmo Hietala
C957T polymorphism of the dopamine D2 receptor (DRD2) gene affects striatal DRD2 availability in vivo.
Molecular psychiatry 2004;9(12):1060-1.
2004: Elina Salmi; Kaike K Kaisti; Liisa Metsähonkala; Vesa Oikonen; Sargo Aalto; Kjell Någren; Susanna Hinkka; Jarmo Hietala; Esa R Korpi; Harry Scheinin
Sevoflurane and propofol increase 11C-flumazenil binding to gamma-aminobutyric acidA receptors in humans.
Anesthesia and analgesia 2004;99(5):1420-6; table of contents.
2004: Valtteri Kaasinen; Sargo Aalto; Kjell Någren; Juha O Rinne
Insular dopamine D2 receptors and novelty seeking personality in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2004;19(11):1348-51.
2004: Antti Pertovaara; Ilkka K Martikainen; Nora Hagelberg; Heikki Mansikka; Kjell Någren; Jarmo Hietala; Harry Scheinin
Striatal dopamine D2/D3 receptor availability correlates with individual response characteristics to pain.
The European journal of neuroscience 2004;20(6):1587-92.
2004: Heikki Minn; Anna Salonen; Johan Friberg; Anne Roivainen; Tapio Viljanen; Jaakko W Långsjö; Jorma Salmi; Matti Välimäki; Kjell Någren; Pirjo Nuutila
Imaging of adrenal incidentalomas with PET using (11)C-metomidate and (18)F-FDG.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(6):972-9.
2004: Nora Hagelberg; Sargo Aalto; Jaana Kajander; Vesa Oikonen; Susanna Hinkka; Kjell Någren; Jarmo Hietala; Harry Scheinin
Alfentanil increases cortical dopamine D2/D3 receptor binding in healthy subjects.
Pain 2004;109(1-2):86-93.
2004: Jari Tiihonen; Anna Keski-Rahkonen; Mari Löppönen; Maria Muhonen; Jaana Kajander; Topias Allonen; Kjell Någren; Jarmo Hietala; Aila Rissanen
Brain serotonin 1A receptor binding in bulimia nervosa.
Biological psychiatry 2004;55(8):871-3.
2004: Valtteri Kaasinen; Sargo Aalto; Kjell Någren; Juha O Rinne
Expectation of caffeine induces dopaminergic responses in humans.
The European journal of neuroscience 2004;19(8):2352-6.
2004: Valtteri Kaasinen; Sargo Aalto; Kjell Någren; Juha O Rinne
Dopaminergic effects of caffeine in the human striatum and thalamus.
Neuroreport 2004;15(2):281-5.
2004: Juha O Rinne; Christer Hublin; Kjell Någren; Hans Helenius; Markku Partinen
Unchanged striatal dopamine transporter availability in narcolepsy: a PET study with [11C]-CFT.
Acta neurologica Scandinavica 2004;109(1):52-5.
2003: Jussi Hirvonen; Sargo Aalto; V Lumme; Kjell Någren; Jaana Kajander; Harry Vilkman; Nora Hagelberg; Vesa Oikonen; Jarmo Hietala
Measurement of striatal and thalamic dopamine D2 receptor binding with 11C-raclopride.
Nuclear medicine communications 2003;24(12):1207-14.
2003: Nora Hagelberg; Heli Forssell; Sargo Aalto; Juha O Rinne; Harry Scheinin; Tero Taiminen; Kjell Någren; Olli Eskola; Satu Jääskeläinen
Altered dopamine D2 receptor binding in atypical facial pain.
Pain 2003;106(1-2):43-8.
2003: Kjell Någren
PET and knockout mice in drug discovery.
Drug discovery today 2003;8(19):876.
2003: Meixiang Yu; Kjell Någren; Y Iris Chen; Eli Livni; David R Elmaleh; Alan P Kozikowski; Xukui Wang; Kimmo Jokivarsi; Anna-Liisa Brownell
Radiolabeling and biodistribution of methyl 2-(methoxycarbonyl)-2-(methylamino) bicyclo[2.1.1] -hexane -5-carboxylate, a potential neuroprotective drug.
Life sciences 2003;73(12):1577-85.
2003: Nina Kemppainen; Matti Laine; M P Laakso; Valtteri Kaasinen; Kjell Någren; Tero Vahlberg; Timo Kurki; Juha O Rinne
Hippocampal dopamine D2 receptors correlate with memory functions in Alzheimer's disease.
The European journal of neuroscience 2003;18(1):149-54.
2003: Nora Hagelberg; Heli Forssell; Juha O Rinne; Harry Scheinin; Tero Taiminen; Sargo Aalto; Sinikka Luutonen; Kjell Någren; Satu Jääskeläinen
Striatal dopamine D1 and D2 receptors in burning mouth syndrome.
Pain 2003;101(1-2):149-54.
2003: Juha O Rinne; Valtteri Kaasinen; Tarja Järvenpää; Kjell Någren; Anne Roivainen; Meixiang Yu; Vesa Oikonen; Timo Kurki
Brain acetylcholinesterase activity in mild cognitive impairment and early Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2003;74(1):113-5.
2003: Eija Sutinen; Sirkku Jyrkkiö; Kalle Alanen; Kjell Någren; Heikki Minn
Uptake of [N-methyl-11C]alpha-methylaminoisobutyric acid in untreated head and neck cancer studied by PET.
European journal of nuclear medicine and molecular imaging 2003;30(1):72-7.
2002: Johan Sandell; Meixiang Yu; Patrick Emond; Lucette Garreau; Sylvie Chalon; Kjell Någren; Denis Guilloteau; Christer Halldin
Synthesis, radiolabeling and preliminary biological evaluation of radiolabeled 5-methyl-6-nitroquipazine, a potential radioligand for the serotonin transporter.
Bioorganic & medicinal chemistry letters 2002;12(24):3611-3.
2002: Sargo Aalto; Jussi Hirvonen; Jaana Kajander; Harry Scheinin; Kjell Någren; Harry Vilkman; Lars ´Gustafsson; Erkka Syvälahti; Jarmo Hietala
Ketamine does not decrease striatal dopamine D2 receptor binding in man.
Psychopharmacology 2002;164(4):401-6.
2002: Valtteri Kaasinen; Kjell Någren; Tarja Järvenpää; Anne Roivainen; Meixiang Yu; Vesa Oikonen; Timo Kurki; Juha O Rinne
Regional effects of donepezil and rivastigmine on cortical acetylcholinesterase activity in Alzheimer's disease.
Journal of clinical psychopharmacology 2002;22(6):615-20.
2002: Markku R Asola; Kirsi A Virtanen; Pauliina Peltoniemi; Kjell Någren; Meixiang Yu; Kari Mattila; Sirkku Jyrkkiö; Kaj Metsärinne; Pirjo Nuutila; Juhani Knuuti
Amino acid uptake in the skeletal muscle measured using [11C]methylaminoisobutyrate (MEAIB) and PET.
European journal of nuclear medicine and molecular imaging 2002;29(11):1485-91.
2002: Meri Utriainen; Liisa Metsähonkala; Toivo T Salmi; Tapio Utriainen; Hannu Kalimo; Helena Pihko; Anne Mäkipernaa; Arja H Harila-Saari; Sirkku Jyrkkiö; Jukka Laine; Kjell Någren; Heikki Minn
Metabolic characterization of childhood brain tumors: comparison of 18F-fluorodeoxyglucose and 11C-methionine positron emission tomography.
Cancer 2002;95(6):1376-86.
2002: Nora Hagelberg; Ilkka K Martikainen; Heikki Mansikka; Susanna Hinkka; Kjell Någren; Jarmo Hietala; Harry Scheinin; Antti Pertovaara
Dopamine D2 receptor binding in the human brain is associated with the response to painful stimulation and pain modulatory capacity.
Pain 2002;99(1-2):273-9.
2002: Johan Sandell; Christer Halldin; Judith Sovago; Yuan-Hwa Chou; Balázs Gulyás; Meixiang Yu; Patrick Emond; Kjell Någren; Denis Guilloteau; Lars Farde
PET examination of [(11)C]5-methyl-6-nitroquipazine, a radioligand for visualization of the serotonin transporter.
Nuclear medicine and biology 2002;29(6):651-6.
2002: Nora Hagelberg; Jaana Kajander; Kjell Någren; Susanna Hinkka; Jarmo Hietala; Harry Scheinin
Mu-receptor agonism with alfentanil increases striatal dopamine D2 receptor binding in man.
Synapse (New York, N.Y.) 2002;45(1):25-30.
2002: Juha O Rinne; HM Ruottinen; Kjell Någren; Laura E Aberg; Pirkko Santavuori
Positron emission tomography shows reduced striatal dopamine D1 but not D2 receptors in juvenile neuronal ceroid lipofuscinosis.
Neuropediatrics 2002;33(3):138-41.
2002: Valtteri Kaasinen; Nina Kemppainen; Kjell Någren; Hans Helenius; Timo Kurki; Juha O Rinne
Age-related loss of extrastriatal dopamine D(2) -like receptors in women.
Journal of neurochemistry 2002;81(5):1005-10.
2002: Mikko Pietilä; Kimmo Malminiemi; Risto Vesalainen; Tuomas Jartti; Mika Teräs; Kjell Någren; Pertti Lehikoinen; Liisa-Maria Voipio-Pulkki
Exercise training in chronic heart failure: beneficial effects on cardiac (11)C-hydroxyephedrine PET, autonomic nervous control, and ventricular repolarization.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2002;43(6):773-9.
2002: Juha O Rinne; M Laine; Valtteri Kaasinen; MK Norvasuo-Heilä; Kjell Någren; Hans Helenius
Striatal dopamine transporter and extrapyramidal symptoms in frontotemporal dementia.
Neurology 2002;58(10):1489-93.
2001: Jussi Hirvonen; Kjell Någren; Jaana Kajander; Jarmo Hietala
Measurement of cortical dopamine d1 receptor binding with 11C[SCH23390]: a test-retest analysis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(10):1146-50.
2001: Eija Sutinen; Sirkku Jyrkkiö; Tove Grönroos; Merja Haaparanta; Pertti Lehikoinen; Kjell Någren
Biodistribution of [11C] methylaminoisobutyric acid, a tracer for PET studies on system A amino acid transport in vivo.
European journal of nuclear medicine 2001;28(7):847-54.
2001: Mikko Pietilä; Kimmo Malminiemi; Heikki Ukkonen; Markku Saraste; Kjell Någren; Pertti Lehikoinen; Liisa-Maria Voipio-Pulkki
Reduced myocardial carbon-11 hydroxyephedrine retention is associated with poor prognosis in chronic heart failure.
European journal of nuclear medicine 2001;28(3):373-6.
2001: Heikki Ukkonen; Juhani Knuuti; C Katoh; H Iida; Hannu Sipilä; Pertti Lehikoinen; Kjell Någren; Liisa-Maria Voipio-Pulkki
Use of [11C]acetate and [15O]O2 PET for the assessment of myocardial oxygen utilization in patients with chronic myocardial infarction.
European journal of nuclear medicine 2001;28(3):334-9.
2001: Juhani Knuuti; Teemu Takala; Kjell Någren; Hannu Sipilä; Anu K Turpeinen; M I J Uusitupa; Pirjo Nuutila
Myocardial fatty acid oxidation in patients with impaired glucose tolerance.
Diabetologia 2001;44(2):184-7.
2001: Valtteri Kaasinen; Kjell Någren; Jarmo Hietala; Lars Farde; Juha O Rinne
Sex differences in extrastriatal dopamine d(2)-like receptors in the human brain.
The American journal of psychiatry 2001;158(2):308-11.
2000: O Langer; Christer Halldin; Y Chou; Johan Sandell; Carl-Gunnar Swahn; Kjell Någren; Roberto Perrone; Francesco Berardi; Marcello Leopoldo; Lars Farde
Carbon-11 pb-12: an attempt to visualize the dopamine d(4) receptor in the primate brain with positron emission tomography.
Nuclear medicine and biology 2000;27(8):707-14.
2000: Harry Vilkman; Jaana Kajander; Kjell Någren; Vesa Oikonen; Erkka Syvälahti; Jarmo Hietala
Measurement of extrastriatal D2-like receptor binding with [11C]FLB 457--a test-retest analysis.
European journal of nuclear medicine 2000;27(11):1666-73.
2000: Heikki Ukkonen; Markku Saraste; Juha Akkila; Juhani Knuuti; M Karanko; H Iida; Pertti Lehikoinen; Kjell Någren; Lasse Lehtonen; Liisa-Maria Voipio-Pulkki
Myocardial efficiency during levosimendan infusion in congestive heart failure.
Clinical pharmacology and therapeutics 2000;68(5):522-31.
2000: Valtteri Kaasinen; Harry Vilkman; Jarmo Hietala; Kjell Någren; Hans Helenius; H Olsson; Lars Farde; J Rinne
Age-related dopamine D2/D3 receptor loss in extrastriatal regions of the human brain.
Neurobiology of aging 2000;21(5):683-8.
2000: Vesa Oikonen; Topias Allonen; Kjell Någren; Jaana Kajander; Jarmo Hietala
Quantification of [Carbonyl-(11)C]WAY-100635 binding: considerations on the cerebellum.
Nuclear medicine and biology 2000;27(5):483-6.
2000: Salla Lamusuo; Asla Pitkänen; Leena Jutila; Aarne Ylinen; Kaarina Partanen; Reetta Kälviäinen; HM Ruottinen; Vesa Oikonen; Kjell Någren; Pertti Lehikoinen; Matti Vapalahti; Pauli Vainio; Juha O Rinne
[11 C]Flumazenil binding in the medial temporal lobe in patients with temporal lobe epilepsy: correlation with hippocampal MR volumetry, T2 relaxometry, and neuropathology.
Neurology 2000;54(12):2252-60.
2000: Valtteri Kaasinen; Kjell Någren; Jarmo Hietala; Vesa Oikonen; Harry Vilkman; Lars Farde; Christer Halldin; Juha O Rinne
Extrastriatal dopamine D2 and D3 receptors in early and advanced Parkinson's disease.
Neurology 2000;54(7):1482-7.
2000: Valtteri Kaasinen; HM Ruottinen; Kjell Någren; Pertti Lehikoinen; Vesa Oikonen; Juha O Rinne
Upregulation of putaminal dopamine D2 receptors in early Parkinson's disease: a comparative PET study with [11C] raclopride and [11C]N-methylspiperone.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(1):65-70.
1999: Risto Vesalainen; Mikko Pietilä; Kari U O Tahvanainen; Tuomas Jartti; Mika Teräs; Kjell Någren; Pertti Lehikoinen; Risto Huupponen; Heikki Ukkonen; Markku Saraste; Juhani Knuuti; Liisa-Maria Voipio-Pulkki
Cardiac positron emission tomography imaging with [11C]hydroxyephedrine, a specific tracer for sympathetic nerve endings, and its functional correlates in congestive heart failure.
The American journal of cardiology 1999;84(5):568-74.
1999: Tiina Pohjalainen; Kjell Någren; Erkka Syvälahti; Jarmo Hietala
The dopamine D2 receptor 5'-flanking variant, -141C Ins/Del, is not associated with reduced dopamine D2 receptor density in vivo.
Pharmacogenetics 1999;9(4):505-9.
1999: Hanna Kanerva; Harry Vilkman; Kjell Någren; O Kilkku; M Kuoppamäki; Erkka Syvälahti; Jarmo Hietala
Brain 5-HT2A receptor occupancy of deramciclane in humans after a single oral administration--a positron emission tomography study.
Psychopharmacology 1999;145(1):76-81.
1999: Jarmo Hietala; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; Erkka Syvälahti
Measurement of striatal D2 dopamine receptor density and affinity with [11C]-raclopride in vivo: a test-retest analysis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(2):210-7.
1998: JM Nuutinen; S Leskinen; Paula Lindholm; Karl-Ove Söderström; Kjell Någren; Sakke Huhtala; Heikki Minn
Use of carbon-11 methionine positron emission tomography to assess malignancy grade and predict survival in patients with lymphomas.
European journal of nuclear medicine 1998;25(7):729-35.
1998: Tiina Pohjalainen; Juha O Rinne; Kjell Någren; Erkka Syvälahti; Jarmo Hietala
Sex differences in the striatal dopamine D2 receptor binding characteristics in vivo.
The American journal of psychiatry 1998;155(6):768-73.
1998: Tiina Pohjalainen; Juha O Rinne; Kjell Någren; Pertti Lehikoinen; K Anttila; Erkka Syvälahti; Jarmo Hietala
The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers.
Molecular psychiatry 1998;3(3):256-60.
1998: Juha O Rinne; N Sahlberg; HM Ruottinen; Kjell Någren; Pertti Lehikoinen
Striatal uptake of the dopamine reuptake ligand [11C]beta-CFT is reduced in Alzheimer's disease assessed by positron emission tomography.
Neurology 1998;50(1):152-6.
1997: S Leskinen; K Pulkki; Juhani Knuuti; Olli A Kirvelä; Pertti Lehikoinen; Kjell Någren; Ulla Ruotsalainen; Mika Teräs; U Wegelius; Eeva Salminen
Transport of carbon-11-methionine is enhanced by insulin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(12):1967-70.
1997: Jarmo Hietala; M Kuoppamäki; Kjell Någren; Pertti Lehikoinen; Erkka Syvälahti
Effects of lorazepam administration on striatal dopamine D2 receptor binding characteristics in man--a positron emission tomography study.
Psychopharmacology 1997;132(4):361-5.
1997: Heikki Ukkonen; Markku Saraste; Juha Akkila; Juhani Knuuti; Pertti Lehikoinen; Kjell Någren; Lasse Lehtonen; Liisa-Maria Voipio-Pulkki
Myocardial efficiency during calcium sensitization with levosimendan: a noninvasive study with positron emission tomography and echocardiography in healthy volunteers.
Clinical pharmacology and therapeutics 1997;61(5):596-607.
1997: Tiina Pohjalainen; A Cravchik; Pablo V Gejman; J Rinne; Kjell Någren; Erkka Syvälahti; Jarmo Hietala
Antagonist binding characteristics of the Ser311-->Cys variant of human dopamine D2 receptor in vivo and in vitro.
Biochemical and biophysical research communications 1997;232(1):143-6.
1996: Juha O Rinne; C Hublin; M Partinen; HM Ruottinen; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; A Laihinen
Striatal dopamine D1 receptors in narcolepsy: a PET study with [11C]NNC 756.
Journal of sleep research 1996;5(4):262-4.
1996: Jari Tiihonen; M Kuoppamäki; Kjell Någren; Jörgen Bergman; E Eronen; Erkka Syvälahti; Jarmo Hietala
Serotonergic modulation of striatal D2 dopamine receptor binding in humans measured with positron emission tomography.
Psychopharmacology 1996;126(4):277-80.
1996: Kjell Någren; Christer Halldin; Carl-Gunnar Swahn; T Suhara; Lars Farde
[11C]metaraminol, a false neurotransmitter: preparation, metabolite studies and positron emission tomography examination in monkey.
Nuclear medicine and biology 1996;23(3):221-7.
1995: M Lapela; S Leskinen-Kallio; M Varpula; Seija Grénman; T Salmi; Kalle Alanen; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; Mika Teräs
Metabolic imaging of ovarian tumors with carbon-11-methionine: a PET study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(12):2196-200.
1995: Kjell Någren; Christer Halldin; L Müller; Carl-Gunnar Swahn; Pertti Lehikoinen
Comparison of [11C]methyl triflate and [11C]methyl iodide in the synthesis of PET radioligands such as [11C]beta-CIT and [11C]beta-CFT.
Nuclear medicine and biology 1995;22(8):965-79.
1995: Lars Farde; Christer Halldin; Kjell Någren; Per Karlsson; Carl-Gunnar Swahn; T Suhara
PET examination of the monkey heart with high specific radioactivity [11C]norepinephrine and [11C]metaraminol.
Nuclear medicine and biology 1995;22(8):1053-6.
1995: Carl-Gunnar Swahn; Christer Halldin; Kjell Någren; Lars Farde
An HPLC-method for determination of ligand metabolism during PET studies with [11C]metaraminol and [11C]norepinephrine.
Nuclear medicine and biology 1995;22(8):1045-8.
1995: Kjell Någren; Christer Halldin; Carl-Gunnar Swahn; K O Schoeps; O Langer; M Mitterhauser; I Zolle
Some new methods for the synthesis of cardiac neurotransmission PET radiotracers.
Nuclear medicine and biology 1995;22(8):1037-43.
1995: Juha O Rinne; A Laihinen; Kjell Någren; HM Ruottinen; Ulla Ruotsalainen; UK Rinne
PET examination of the monoamine transporter with [11C]beta-CIT and [11C]beta-CFT in early Parkinson's disease.
Synapse (New York, N.Y.) 1995;21(2):97-103.
1995: Juha O Rinne; A Laihinen; HM Ruottinen; Ulla Ruotsalainen; Kjell Någren; Pertti Lehikoinen; Vesa Oikonen; UK Rinne
Increased density of dopamine D2 receptors in the putamen, but not in the caudate nucleus in early Parkinson's disease: a PET study with [11C]raclopride.
Journal of the neurological sciences 1995;132(2):156-61.
1995: Paula Lindholm; S Leskinen; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; Mika Teräs; Heikki Joensuu
Carbon-11-methionine PET imaging of malignant melanoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(10):1806-10.
1995: Juha O Rinne; C Hublin; M Partinen; HM Ruottinen; Ulla Ruotsalainen; Kjell Någren; Pertti Lehikoinen; A Laihinen
Positron emission tomography study of human narcolepsy: no increase in striatal dopamine D2 receptors.
Neurology 1995;45(9):1735-8.
1995: A O Laihinen; Juha O Rinne; Kjell Någren; Pertti Lehikoinen; Vesa Oikonen; Ulla Ruotsalainen; HM Ruottinen; UK Rinne
PET studies on brain monoamine transporters with carbon-11-beta-CIT in Parkinson's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(7):1263-7.
1995: Paula Lindholm; S Leskinen-Kallio; Reidar Grénman; Pertti Lehikoinen; Kjell Någren; Mika Teräs; Ulla Ruotsalainen; Heikki Joensuu
Evaluation of response to radiotherapy in head and neck cancer by positron emission tomography and [11C]methionine.
International journal of radiation oncology, biology, physics 1995;32(3):787-94.
1995: Kjell Någren; L Müller; Christer Halldin; Carl-Gunnar Swahn; Pertti Lehikoinen
Improved synthesis of some commonly used PET radioligands by the use of [11C]methyl triflate.
Nuclear medicine and biology 1995;22(2):235-9.
1994: A O Laihinen; Juha O Rinne; HM Ruottinen; Kjell Någren; Pertti Lehikoinen; Vesa Oikonen; Ulla Ruotsalainen; UK Rinne
PET studies on dopamine D1 receptors in the human brain with carbon-11-SCH 39166 and carbon-11-NNC 756.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(12):1916-20.
1994: Jarmo Hietala; C West; Erkka Syvälahti; Kjell Någren; Pertti Lehikoinen; Pirkko Sonninen; Ulla Ruotsalainen
Striatal D2 dopamine receptor binding characteristics in vivo in patients with alcohol dependence.
Psychopharmacology 1994;116(3):285-90.
1994: M Lapela; S Leskinen-Kallio; M Varpula; S Grenman; Kalle Alanen; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; Mika Teräs; Heikki Joensuu
Imaging of uterine carcinoma by carbon-11-methionine and PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(10):1618-23.
1994: Kjell Någren; K O Schoeps; Christer Halldin; Carl-Gunnar Swahn; Lars Farde
Selective synthesis of racemic 1-11C-labelled norepinephrine, octopamine, norphenylephrine and phenylethanolamine using [11C]nitromethane.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1994;45(4):515-21.
1994: Lars Farde; Christer Halldin; Kjell Någren; T Suhara; Per Karlsson; K O Schoeps; Carl-Gunnar Swahn; D Bone
Positron emission tomography shows high specific uptake of racemic carbon-11 labelled norepinephrine in the primate heart.
European journal of nuclear medicine 1994;21(4):345-7.
1994: Paula Lindholm; S Leskinen-Kallio; Olli A Kirvelä; Kjell Någren; Pertti Lehikoinen; Kari Pulkki; O Peltola; Ulla Ruotsalainen; Mika Teräs; Heikki Joensuu
Head and neck cancer: effect of food ingestion on uptake of C-11 methionine.
Radiology 1994;190(3):863-7.
1994: Jarmo Hietala; Erkka Syvälahti; K Vuorio; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; V Räkköläinen; Ville Lehtinen; U Wegelius
Striatal D2 dopamine receptor characteristics in neuroleptic-naive schizophrenic patients studied with positron emission tomography.
Archives of general psychiatry 1994;51(2):116-23.
1993: Paula Lindholm; S Leskinen-Kallio; Heikki Minn; Jörgen Bergman; Merja Haaparanta; Pertti Lehikoinen; Kjell Någren; Ulla Ruotsalainen; Mika Teräs; Heikki Joensuu
Comparison of fluorine-18-fluorodeoxyglucose and carbon-11-methionine in head and neck cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(10):1711-6.
1993: K O Schoeps; Christer Halldin; Kjell Någren; Carl-Gunnar Swahn; Per Karlsson; Håkan Hall; Lars Farde
Preparation of [1-11C]dopamine, [1-11C]p-tyramine and [1-11C]m-tyramine. Autoradiography and PET examination of [1-11C]dopamine in primates.
Nuclear medicine and biology 1993;20(5):669-78.
1993: Juha O Rinne; A Laihinen; UK Rinne; Kjell Någren; Jörgen Bergman; Ulla Ruotsalainen
PET study on striatal dopamine D2 receptor changes during the progression of early Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1993;8(2):134-8.
1993: R Huovinen; S Leskinen-Kallio; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; Mika Teräs
Carbon-11-methionine and PET in evaluation of treatment response of breast cancer.
British journal of cancer 1993;67(4):787-91.
1993: Juha O Rinne; Jarmo Hietala; Ulla Ruotsalainen; E Säkö; A Laihinen; Kjell Någren; Pertti Lehikoinen; Vesa Oikonen; Erkka Syvälahti
Decrease in human striatal dopamine D2 receptor density with age: a PET study with [11C]raclopride.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(2):310-4.
1992: Christer Halldin; Kjell Någren; Carl-Gunnar Swahn; B Långström; H Nybäck
(S)- and (R)-[11C]nicotine and the metabolite (R/S)-[11C]cotinine. Preparation, metabolite studies and in vivo distribution in the human brain using PET.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992;19(8):871-80.
1992: S Leskinen-Kallio; R Huovinen; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; Mika Teräs; Heikki Joensuu
[11C]methionine quantitation in cancer PET studies.
Journal of computer assisted tomography 1992;16(3):468-74.
1992: S Leskinen-Kallio; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; Mika Teräs; Heikki Joensuu
Carbon-11-methionine and PET is an effective method to image head and neck cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1992;33(5):691-5.
1991: S Leskinen-Kallio; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; Heikki Joensuu
Uptake of 11C-methionine in breast cancer studied by PET. An association with the size of S-phase fraction.
British journal of cancer 1991;64(6):1121-4.
1991: S Leskinen-Kallio; Ulla Ruotsalainen; Kjell Någren; Mika Teräs; Heikki Joensuu
Uptake of carbon-11-methionine and fluorodeoxyglucose in non-Hodgkin's lymphoma: a PET study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(6):1211-8.
1991: T Takahashi; Kjell Någren; K Aho
Convenient synthesis of DL-[1-11C]alanine.
Acta radiologica. Supplementum 1991;376():96-7.
1991: Juha O Rinne; A Laihinen; Kjell Någren; Jörgen Bergman; Merja Haaparanta; Olof Solin; Ulla Ruotsalainen; UK Rinne
Positron emission tomography of brain dopamine D-1 receptors with 11C-SCH 23390 in Parkinson's disease.
Acta radiologica. Supplementum 1991;376():152.
1991: A Laihinen; Juha O Rinne; Kjell Någren; Jörgen Bergman; Merja Haaparanta; Olof Solin; Ulla Ruotsalainen; UK Rinne
Positron emission tomography of brain dopamine D-2 receptors with 11C-raclopride in early Parkinson's disease.
Acta radiologica. Supplementum 1991;376():151.
1991: Liisa-Maria Voipio-Pulkki; U Ruotsalainen; Pirjo Nuutila; Kjell Någren
Myocardial 11C-palmitate kinetics in patients with coronary heart disease. Effect of non-insulin dependent diabetes mellitus.
Acta radiologica. Supplementum 1991;376():142-3.
1991: Per Hartvig; A Waldenström; G Wikström; Tomasz Zielinski; H J Martinussen; J Carlsten; Liisa-Maria Voipio-Pulkki; Hans Lundqvist; P Bjurling; Kjell Någren
Metabolism of [1-11C]palmitate in the diabetic heart studied in a porcine model using positron emission tomography.
Acta radiologica. Supplementum 1991;376():137-8.
1990: Juha O Rinne; A Laihinen; Kjell Någren; Jörgen Bergman; Olof Solin; Merja Haaparanta; Ulla Ruotsalainen; UK Rinne
PET demonstrates different behaviour of striatal dopamine D-1 and D-2 receptors in early Parkinson's disease.
Journal of neuroscience research 1990;27(4):494-9.
1990: UK Rinne; A Laihinen; Juha O Rinne; Kjell Någren; Jörgen Bergman; Ulla Ruotsalainen
Positron emission tomography demonstrates dopamine D2 receptor supersensitivity in the striatum of patients with early Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1990;5(1):55-9.
1990: Bengt Långström; Gunnar Antoni; P Bjurling; Karl-Johan Fasth; A D Gee; Kjell Någren; J Ulin
Synthesis of compounds of interest for positron emission tomography with particular reference to synthetic strategies for 11C labeling.
Acta radiologica. Supplementum 1990;374():147-51.
1989: Per Hartvig; A Waldenström; G Wikström; Tomasz Zielinski; H J Martinussen; J Carslsten; Liisa-Maria Voipio-Pulkki; Hans Lundqvist; P Bjurling; Kjell Någren
The diabetic heart: a porcine model evaluated with positron emission tomography using 1-11C-palmitate and 3-11C-pyruvate.
Diabetes research (Edinburgh, Scotland) 1989;12(1):1-5.
1988: R d'Argy; R Paul; L Frankenberg; C G Stålnacke; Hans Lundqvist; L Kangas; Christer Halldin; Kjell Någren; D Roeda; Merja Haaparanta
Comparative double-tracer whole-body autoradiography: uptake of 11C-, 18F- and 3H-labeled compounds in rat tumors.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1988;15(5):577-85.