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Fred Naider

Research Profile

Chemicals & Drugs

Living Beings

Saccharomyces cerevisiae

Genes & Molecular Sequences

Amino Acid Sequences

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Procedures

High Pressure Liquid Chromatography

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Publications

TOP 3
Einat Schnur; Alexander Tsimanis; Yuri Zherdev; Boris Arshava; Fa-Xiang Ding; Naama Kessler; Victoria Kurbatska; Ainars Leonciks; Fred Naider; Eran Noah; Svetlana Rabinovich; Osnat Rosen; Tali Scherf; Jacob Anglister
NMR mapping of RANTES surfaces interacting with CCR5 using linked extracellular domains.
Adi Moseri; Fred Naider; Subramanyam Tantry; Fa-Xiang Ding; Jacob Anglister
Short communication: synergism between a CD4-mimic peptide and antibodies elicited by a constrained V3 peptide.
Elizabeth Mathew; Fred Naider; Fa-Xiang Ding; Mark E Dumont
Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast.

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All Publications

2013: Einat Schnur; Alexander Tsimanis; Yuri Zherdev; Boris Arshava; Fa-Xiang Ding; Naama Kessler; Victoria Kurbatska; Ainars Leonciks; Fred Naider; Eran Noah; Svetlana Rabinovich; Osnat Rosen; Tali Scherf; Jacob Anglister
NMR mapping of RANTES surfaces interacting with CCR5 using linked extracellular domains.
The FEBS journal 2013;280(9):2068-84.
2013: Adi Moseri; Fred Naider; Subramanyam Tantry; Fa-Xiang Ding; Jacob Anglister
Short communication: synergism between a CD4-mimic peptide and antibodies elicited by a constrained V3 peptide.
AIDS research and human retroviruses 2013;29(4):718-24.
2013: Elizabeth Mathew; Fred Naider; Fa-Xiang Ding; Mark E Dumont
Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast.
Protein engineering, design & selection : PEDS 2013;26(1):59-71.
2012: Xuan Shao; Fred Naider; Chao Zou; Oliver Zerbe
Comparison of fragments comprising the first two helices of the human Y4 and the yeast Ste2p G-protein-coupled receptors.
Biophysical journal 2012;103(4):817-26.
2012: M Seraj Uddin; Amanda Deyo; Heejung Kim; Fred Naider; Jeffrey M Becker
Identification of residues involved in homodimer formation located within a β-strand region of the N-terminus of a Yeast G protein-coupled receptor.
Journal of receptor and signal transduction research 2012;32(2):65-75.
2012: Zhanna Potetinova; Subramanyam Tantry; Boris Arshava; Jeffrey M Becker; Katrina E Caroccia; Leah S Cohen; Fred Naider
Large multiple transmembrane domain fragments of a G protein-coupled receptor: biosynthesis, purification, and biophysical studies.
Biopolymers 2012;98(5):485-500.
2012: Kyeong-Man Kim; Yong-Hun Lee; Fred Naider; M Seraj Uddin; Ayca Akal-Strader; Melinda Hauser; Jeffrey M Becker
Multiple regulatory roles of the carboxy terminus of Ste2p a yeast GPCR.
Pharmacological research : the official journal of the Italian Pharmacological Society 2012;65(1):31-40.
2011: L S Cohen; P Güntert; Boris Arshava; Jeffrey M Becker; Alexey Neumoin; O Zerbe; Fred Naider
Comparative NMR analysis of an 80-residue G protein-coupled receptor fragment in two membrane mimetic environments.
Biochimica et biophysica acta 2011;1808(11):2674-84.
2011: Jordan H Chill; Fred Naider
A solution NMR view of protein dynamics in the biological membrane.
Current opinion in structural biology 2011;21(5):627-33.
2011: George K E Umanah; Li-Yin Huang; Julianna M Maccarone; Fred Naider; Jeffrey M Becker
Changes in conformation at the cytoplasmic ends of the fifth and sixth transmembrane helices of a yeast G protein-coupled receptor in response to ligand binding.
Biochemistry 2011;50(32):6841-54.
2011: Einat Schnur; Boris Arshava; Inbal Ayzenshtat; Fa-Xiang Ding; Tatsuya Inui; Naama Kessler; Rina Levy; Fred Naider; Eran Noah; Yael Sagi; Hasmik Sargsyan; Tali Scherf; Jacob Anglister
The conformation and orientation of a 27-residue CCR5 peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide.
Journal of molecular biology 2011;410(5):778-97.
2011: Elizabeth Mathew; Anshika Bajaj; Sara M Connelly; Hasmik Sargsyan; Fa-Xiang Ding; Alexander G Hajduczok; Fred Naider; Mark E Dumont
Differential interactions of fluorescent agonists and antagonists with the yeast G protein coupled receptor Ste2p.
Journal of molecular biology 2011;409(4):513-28.
2011: Katrina E Caroccia; Leah S Cohen; Rima Estephan; Melinda Hauser; Boris Arshava; Jeffrey M Becker; Oliver Zerbe; Fred Naider
Expression and biophysical analysis of a triple-transmembrane domain-containing fragment from a yeast G protein-coupled receptor.
Biopolymers 2011;96(6):757-71.
2011: Daniel G Mullen; Kelly Kyro; Melinda Hauser; Martin Gustavsson; Gianluigi Veglia; Jeffery M Becker; Fred Naider; Mark D Distefano
Synthesis of a-factor peptide from Saccharomyces cerevisiae and photoactive analogues via Fmoc solid phase methodology.
Bioorganic & medicinal chemistry 2011;19(1):490-7.
2010: George K E Umanah; Liyin Huang; Fa-Xiang Ding; Boris Arshava; Adam R Farley; Andrew J Link; Fred Naider; Jeffrey M Becker
Identification of residue-to-residue contact between a peptide ligand and its G protein-coupled receptor using periodate-mediated dihydroxyphenylalanine cross-linking and mass spectrometry.
The Journal of biological chemistry 2010;285(50):39425-36.
2010: Subramanyam Tantry; Fa-Xiang Ding; Mark Dumont; Jeffrey M Becker; Fred Naider
Binding of fluorinated phenylalanine alpha-factor analogues to Ste2p: evidence for a cation-pi binding interaction between a peptide ligand and its cognate G protein-coupled receptor.
Biochemistry 2010;49(24):5007-15.
2010: Adi Moseri; Subramanyam Tantry; Yael Sagi; Boris Arshava; Fred Naider; Jacob Anglister
An optimally constrained V3 peptide is a better immunogen than its linear homolog or HIV-1 gp120.
Virology 2010;401(2):293-304.
2010: Leah S Cohen; Jeffrey M Becker; Fred Naider
Biosynthesis of peptide fragments of eukaryotic GPCRs in Escherichia coli by directing expression into inclusion bodies.
Journal of peptide science : an official publication of the European Peptide Society 2010;16(5):213-8.
2009: Heejung Kim; Byung-Kwon Lee; Fred Naider; Jeffrey M Becker
Identification of specific transmembrane residues and ligand-induced interface changes involved in homo-dimer formation of a yeast G protein-coupled receptor.
Biochemistry 2009;48(46):10976-87.
2009: Brenda Mester; Revital Manor; Amit Mor; Boris Arshava; Osnat Rosen; Fa-Xiang Ding; Fred Naider; Jacob Anglister
HIV-1 peptide vaccine candidates: selecting constrained V3 peptides with highest affinity to antibody 447-52D.
Biochemistry 2009;48(33):7867-77.
2009: Fred Naider; Jacob Anglister
Peptides in the treatment of AIDS.
Current opinion in structural biology 2009;19(4):473-82.
2009: Alexey Neumoin; Leah S Cohen; Boris Arshava; Subramanyam Tantry; Jeffrey M Becker; Oliver Zerbe; Fred Naider
Structure of a double transmembrane fragment of a G-protein-coupled receptor in micelles.
Biophysical journal 2009;96(8):3187-96.
2009: Amit Mor; Eugenia Segal; Brenda Mester; Boris Arshava; Osnat Rosen; Fa-Xiang Ding; Joseph Russo; Amnon Dafni; Fabian Schvartzman; Tali Scherf; Fred Naider; Jacob Anglister
Mimicking the structure of the V3 epitope bound to HIV-1 neutralizing antibodies.
Biochemistry 2009;48(15):3288-303.
2009: George K E Umanah; Cagdas Son; FaXiang Ding; Fred Naider; Jeffrey M Becker
Cross-linking of a DOPA-containing peptide ligand into its G protein-coupled receptor.
Biochemistry 2009;48(9):2033-44.
2009: George Umanah; Li-Yin Huang; Peter G Schultz; Fred Naider; Jeffrey M Becker
Incorporation of the unnatural amino acid p-benzoyl-L-phenylalanine (Bpa) into a G protein-coupled receptor in its native context.
Advances in experimental medicine and biology 2009;611():333-5.
2009: Fred Naider; Alexey Neumoin; Boris Arshava; Leah S Cohen; Jeffrey M Becker; Oliver Zerbe
Structural studies on large fragments of G protein coupled receptors.
Advances in experimental medicine and biology 2009;611():309-10.
2009: Leah S Cohen; Boris Arshava; Racha Estephan; Jacqueline Englander; Melinda Hauser; Jeffrey M Becker; Fred Naider
Expression of double transmembrane domain GPCR fragments for biophysical analysis.
Advances in experimental medicine and biology 2009;611():303-4.
2008: Chao Zou; Fred Naider; Oliver Zerbe
Biosynthesis and NMR-studies of a double transmembrane domain from the Y4 receptor, a human GPCR.
Journal of biomolecular NMR 2008;42(4):257-69.
2008: Eran Noah; Zohar Biron; Fred Naider; Boris Arshava; Jacob Anglister
The membrane proximal external region of the HIV-1 envelope glycoprotein gp41 contributes to the stabilization of the six-helix bundle formed with a matching N' peptide.
Biochemistry 2008;47(26):6782-92.
2008: Li-Yin Huang; George Umanah; Melinda Hauser; Cagdas Son; Boris Arshava; Fred Naider; Jeffrey M Becker
Unnatural amino acid replacement in a yeast G protein-coupled receptor in its native environment.
Biochemistry 2008;47(20):5638-48.
2008: Leah S Cohen; Boris Arshava; Rima Estephan; Jacqueline Englander; Heejung Kim; Melinda Hauser; Oliver Zerbe; Marco Ceruso; Jeffrey M Becker; Fred Naider
Expression and biophysical analysis of two double-transmembrane domain-containing fragments from a yeast G protein-coupled receptor.
Biopolymers 2008;90(2):117-30.
2007: Byung-Kwon Lee; Kyung-Sik Jung; Cagdas Son; Heejung Kim; Nathan C VerBerkmoes; Boris Arshava; Fred Naider; Jeffrey M Becker
Affinity purification and characterization of a G-protein coupled receptor, Saccharomyces cerevisiae Ste2p.
Protein expression and purification 2007;56(1):62-71.
2007: Houjian Cai; Melinda Hauser; Fred Naider; Jeffrey M Becker
Differential regulation and substrate preferences in two peptide transporters of Saccharomyces cerevisiae.
Eukaryotic cell 2007;6(10):1805-13.
2007: Alexey Neumoin; Boris Arshava; Jeff Becker; Oliver Zerbe; Fred Naider
NMR studies in dodecylphosphocholine of a fragment containing the seventh transmembrane helix of a G-protein-coupled receptor from Saccharomyces cerevisiae.
Biophysical journal 2007;93(2):467-82.
2007: Anshika Bajaj; Sara M Connelly; Austin U Gehret; Fred Naider; Mark E Dumont
Role of extracellular charged amino acids in the yeast alpha-factor receptor.
Biochimica et biophysica acta 2007;1773(6):707-17.
2007: Melinda Hauser; Sarah Kauffman; Byung-Kwon Lee; Fred Naider; Jeffrey M Becker
The first extracellular loop of the Saccharomyces cerevisiae G protein-coupled receptor Ste2p undergoes a conformational change upon ligand binding.
The Journal of biological chemistry 2007;282(14):10387-97.
2007: Fred Naider; Jeffrey M Becker; Yong-Hun Lee; Amnon Horovitz
Double-mutant cycle scanning of the interaction of a peptide ligand and its G protein-coupled receptor.
Biochemistry 2007;46(11):3476-81.
2007: Fred Naider
Synthesis, biosynthesis, and characterization of transmembrane domains of a G protein-coupled receptor.
Methods in molecular biology (Clifton, N.J.) 2007;386():95-121.
2006: Patricia Cano-Sanchez; Beatrice Severino; V V Sureshbabu; Joe Russo; Tatsuya Inui; Fa-Xiang Ding; Boris Arshava; Jeff Becker; Fred Naider
Effects of N- and C-terminal addition of oligolysines or native loop residues on the biophysical properties of transmembrane domain peptides from a G-protein coupled receptor.
Journal of peptide science : an official publication of the European Peptide Society 2006;12(12):808-22.
2006: Amy Wiles; Houjian Cai; Fred Naider; Jeffrey M Becker
Nutrient regulation of oligopeptide transport in Saccharomyces cerevisiae.
Microbiology (Reading, England) 2006;152(Pt 10):3133-45.
2006: Austin U Gehret; Anshika Bajaj; Fred Naider; Mark E Dumont
Oligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors.
The Journal of biological chemistry 2006;281(30):20698-714.
2006: Amy Wiles; Fred Naider; Jeffrey M Becker
Transmembrane domain prediction and consensus sequence identification of the oligopeptide transport family.
Research in microbiology 2006;157(4):395-406.
2006: Houjian Cai; Sarah Kauffman; Fred Naider; Jeffrey M Becker
Genomewide screen reveals a wide regulatory network for di/tripeptide utilization in Saccharomyces cerevisiae.
Genetics 2006;172(3):1459-76.
2006: Yong-Hun Lee; Fred Naider; Jeffrey M Becker
Interacting residues in an activated state of a G protein-coupled receptor.
The Journal of biological chemistry 2006;281(4):2263-72.
2006: Jacqueline Englander; Leah Cohen; Boris Arshava; Rima Estephan; Jeffrey M Becker; Fred Naider
Selective labeling of a membrane peptide with 15N-amino acids using cells grown in rich medium.
Biopolymers 2006;84(5):508-18.
2005: Zohar Biron; Sanjay Khare; Sabine R Quadt; Yehezkiel Hayek; Fred Naider; Jacob Anglister
The 2F5 epitope is helical in the HIV-1 entry inhibitor T-20.
Biochemistry 2005;44(41):13602-11.
2005: Rima Estephan; Jacqueline Englander; Boris Arshava; Karen L Samples; Jeffrey M Becker; Fred Naider
Biosynthesis and NMR analysis of a 73-residue domain of a Saccharomyces cerevisiae G protein-coupled receptor.
Biochemistry 2005;44(35):11795-810.
2005: Melinda Hauser; Sarah Kauffman; Fred Naider; Jeffrey M Becker
Substrate preference is altered by mutations in the fifth transmembrane domain of Ptr2p, the di/tri-peptide transporter of Saccharomyces cerevisiae.
Molecular membrane biology 2005;22(3):215-27.
2005: Agnieszka M Janiak; Hasmik Sargsyan; Joe Russo; Fred Naider; Melinda Hauser; Jeffrey M Becker
Functional expression of the Candida albicans alpha-factor receptor in Saccharomyces cerevisiae.
Fungal genetics and biology : FG & B 2005;42(4):328-38.
2005: Cagdas Son; Hasmik Sargsyan; G B Hurst; Fred Naider; Jeffrey M Becker
Analysis of ligand-receptor cross-linked fragments by mass spectrometry.
The journal of peptide research : official journal of the American Peptide Society 2005;65(3):418-26.
2005: Fred Naider; Sanjay Khare; Boris Arshava; Beatrice Severino; Joe Russo; Jeffrey M Becker
Synthetic peptides as probes for conformational preferences of domains of membrane receptors.
Biopolymers 2005;80(2-3):199-213.
2004: Anshika Bajaj; Andjelka Celić; Fa-Xiang Ding; Fred Naider; Jeffrey M Becker; Mark E Dumont
A fluorescent alpha-factor analogue exhibits multiple steps on binding to its G protein coupled receptor in yeast.
Biochemistry 2004;43(42):13564-78.
2004: Cagdas Son; Hasmik Sargsyan; Fred Naider; Jeffrey M Becker
Identification of ligand binding regions of the Saccharomyces cerevisiae alpha-factor pheromone receptor by photoaffinity cross-linking.
Biochemistry 2004;43(41):13193-203.
2004: Fred Naider; Jeffrey M Becker
The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors.
Peptides 2004;25(9):1441-63.
2004: Fred Naider; Rima Estephan; Jacqueline Englander; V V Suresh Babu; Enrique Arevalo; Karen Samples; Jeffrey M Becker
Sexual conjugation in yeast: A paradigm to study G-protein-coupled receptor domain structure.
Biopolymers 2004;76(2):119-28.
2003: Fred Naider; Fa-Xiang Ding; Nathan C VerBerkmoes; Boris Arshava; Jeffrey M Becker
Synthesis and biophysical characterization of a multidomain peptide from a Saccharomyces cerevisiae G protein-coupled receptor.
The Journal of biological chemistry 2003;278(52):52537-45.
2003: Yair Porat; Alex Stepensky; Fa-Xiang Ding; Fred Naider; Ehud Gazit
Completely different amyloidogenic potential of nearly identical peptide fragments.
Biopolymers 2003;69(2):161-4.
2003: Andjelka Celić; Negin P Martin; Cagdas Son; Jeffrey M Becker; Fred Naider; Mark E Dumont
Sequences in the intracellular loops of the yeast pheromone receptor Ste2p required for G protein activation.
Biochemistry 2003;42(10):3004-17.
2003: Enrique Arevalo; Rima Estephan; Jenifer Madeo; Boris Arshava; Mark Dumont; Jeffrey M Becker; Fred Naider
Biosynthesis and biophysical analysis of domains of a yeast G protein-coupled receptor.
Biopolymers 2003;71(4):516-31.
2002: Byung-Kwon Lee; Yong-Hun Lee; Melinda Hauser; Cagdas Son; Sanjay Khare; Fred Naider; Jeffrey M Becker
Tyr266 in the sixth transmembrane domain of the yeast alpha-factor receptor plays key roles in receptor activation and ligand specificity.
Biochemistry 2002;41(46):13681-9.
2002: Zohar Biron; Sanjay Khare; Abraham O Samson; Yehezkiel Hayek; Fred Naider; Jacob Anglister
A monomeric 3(10)-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41.
Biochemistry 2002;41(42):12687-96.
2002: Ayça Akal-Strader; Sanjay Khare; Dong Xu; Fred Naider; Jeffrey M Becker
Residues in the first extracellular loop of a G protein-coupled receptor play a role in signal transduction.
The Journal of biological chemistry 2002;277(34):30581-90.
2002: Boris Arshava; Irina Taran; Haibo Xie; Jeffrey M Becker; Fred Naider
High resolution NMR analysis of the seven transmembrane domains of a heptahelical receptor in organic-aqueous medium.
Biopolymers 2002;64(3):161-76.
2002: Fa-Xiang Ding; Byung-Kwon Lee; M Hauser; R Patri; Boris Arshava; Jeffrey M Becker; Fred Naider
Study of the binding environment of alpha-factor in its G protein-coupled receptor using fluorescence spectroscopy.
The journal of peptide research : official journal of the American Peptide Society 2002;60(1):65-74.
2002: Keith Henry; Sanjay Khare; Cagdas Son; V V Suresh Babu; Fred Naider; Jeffrey M Becker
Identification of a contact region between the tridecapeptide alpha-factor mating pheromone of Saccharomyces cerevisiae and its G protein-coupled receptor by photoaffinity labeling.
Biochemistry 2002;41(19):6128-39.
2002: Fa-Xiang Ding; David Schreiber; Nathan C VerBerkmoes; Jeffrey M Becker; Fred Naider
The chain length dependence of helix formation of the second transmembrane domain of a G protein-coupled receptor of Saccharomyces cerevisiae.
The Journal of biological chemistry 2002;277(17):14483-92.
2002: Serry Koh; Amy Wiles; Joshua S Sharp; Fred Naider; Jeffrey M Becker; Gary Stacey
An oligopeptide transporter gene family in Arabidopsis.
Plant physiology 2002;128(1):21-9.
2001: Byung-Kwon Lee; S Khare; Fred Naider; Jeffrey M Becker
Identification of residues of the Saccharomyces cerevisiae G protein-coupled receptor contributing to alpha-factor pheromone binding.
The Journal of biological chemistry 2001;276(41):37950-61.
2001: Kathleen G Valentine; SF Liu; Francesca M Marassi; Gianluigi Veglia; Stanley J Opella; Fa-Xiang Ding; S H Wang; Boris Arshava; Jeffrey M Becker; Fred Naider
Structure and topology of a peptide segment of the 6th transmembrane domain of the Saccharomyces cerevisae alpha-factor receptor in phospholipid bilayers.
Biopolymers 2001;59(4):243-56.
2001: Fa-Xiang Ding; Haibo Xie; Boris Arshava; Jeffrey M Becker; Fred Naider
ATR-FTIR study of the structure and orientation of transmembrane domains of the Saccharomyces cerevisiae alpha-mating factor receptor in phospholipids.
Biochemistry 2001;40(30):8945-54.
2001: Fa-Xiang Ding; Byung-Kwon Lee; M Hauser; L Davenport; Jeffrey M Becker; Fred Naider
Probing the binding domain of the Saccharomyces cerevisiae alpha-mating factor receptor with rluorescent ligands.
Biochemistry 2001;40(4):1102-8.
2001: Fred Naider; Boris Arshava; Fa-Xiang Ding; Enrique Arevalo; Jeffrey M Becker
Peptide fragments as models to study the structure of a G-protein coupled receptor: the alpha-factor receptor of Saccharomyces cerevisiae.
Biopolymers 2001;60(5):334-50.
2001: M Hauser; V Narita; A M Donhardt; Fred Naider; J M Becker
Multiplicity and regulation of genes encoding peptide transporters in Saccharomyces cerevisiae.
Molecular membrane biology 2001;18(1):105-12.
2000: Haibo Xie; Fa-Xiang Ding; D Schreiber; G Eng; SF Liu; Boris Arshava; Enrique Arevalo; Jeffrey M Becker; Fred Naider
Synthesis and biophysical analysis of transmembrane domains of a Saccharomyces cerevisiae G protein-coupled receptor.
Biochemistry 2000;39(50):15462-74.
2000: S Liu; Keith Henry; Byung-Kwon Lee; S H Wang; Boris Arshava; Jeffrey M Becker; Fred Naider
Position 13 analogs of the tridecapeptide mating pheromone from Saccharomyces cerevisiae: design of an iodinatable ligand for receptor binding.
The journal of peptide research : official journal of the American Peptide Society 2000;56(1):24-34.
2000: CM Sommers; Negin P Martin; A Akal-Strader; Jeffrey M Becker; Fred Naider; Mark E Dumont
A limited spectrum of mutations causes constitutive activation of the yeast alpha-factor receptor.
Biochemistry 2000;39(23):6898-909.
2000: H Xie; Jeffrey M Becker; Richard A Gibbs; Fred Naider
Structure, biological activity and membrane partitioning of analogs of the isoprenylated a-factor mating peptide of Saccharomyces cerevisiae.
The journal of peptide research : official journal of the American Peptide Society 2000;55(5):372-83.
2000: Melinda Hauser; A M Donhardt; D Barnes; Fred Naider; Jeffrey M Becker
Enkephalins are transported by a novel eukaryotic peptide uptake system.
The Journal of biological chemistry 2000;275(5):3037-41.
1999: Boris Arshava; M Breslav; O Antohi; Ruth E Stark; J R Garbow; Jeffrey M Becker; Fred Naider
Long-distance rotational echo double resonance measurements for the determination of secondary structure and conformational heterogeneity in peptides.
Solid state nuclear magnetic resonance 1999;14(2):117-36.
1998: M G Abel; Byung-Kwon Lee; Fred Naider; Jeffrey M Becker
Mutations affecting ligand specificity of the G-protein-coupled receptor for the Saccharomyces cerevisiae tridecapeptide pheromone.
Biochimica et biophysica acta 1998;1448(1):12-26.
1998: Boris Arshava; SF Liu; H Jiang; M Breslav; Jeffrey M Becker; Fred Naider
Structure of segments of a G protein-coupled receptor: CD and NMR analysis of the Saccharomyces cerevisiae tridecapeptide pheromone receptor.
Biopolymers 1998;46(6):343-57.
1998: Y L Zhang; H R Marepalli; H F Lu; Jeffrey M Becker; Fred Naider
Synthesis, biological activity, and conformational analysis of peptidomimetic analogues of the Saccharomyces cerevisiae alpha-factor tridecapeptide.
Biochemistry 1998;37(36):12465-76.
1998: M G Abel; Y L Zhang; H F Lu; Fred Naider; J M Becker
Structure-function analysis of the Saccharomyces cerevisiae tridecapeptide pheromone using alanine-scanned analogs.
The journal of peptide research : official journal of the American Peptide Society 1998;52(2):95-106.
1998: D Barnes; W Lai; M Breslav; Fred Naider; Jeffrey M Becker
PTR3, a novel gene mediating amino acid-inducible regulation of peptide transport in Saccharomyces cerevisiae.
Molecular microbiology 1998;29(1):297-310.
1998: M A Lubkowitz; D Barnes; M Breslav; A Burchfield; Fred Naider; Jeffrey M Becker
Schizosaccharomyces pombe isp4 encodes a transporter representing a novel family of oligopeptide transporters.
Molecular microbiology 1998;28(4):729-41.
1998: O Antohi; H R Marepalli; W Yang; Jeffrey M Becker; Fred Naider
Conformational analysis of cyclic analogues of the Saccharomyces cerevisiae alpha-factor pheromone.
Biopolymers 1998;45(1):21-34.
1997: Y L Zhang; H F Lu; Jeffrey M Becker; Fred Naider
Position one analogs of the Saccharomyces cerevisiae tridecapeptide pheromone.
The journal of peptide research : official journal of the American Peptide Society 1997;50(5):319-28.
1997: A L Dawe; Jeffrey M Becker; Y Jiang; Fred Naider; JT Eummer; Y Q Mu; Richard A Gibbs
Novel modifications to the farnesyl moiety of the a-factor lipopeptide pheromone from Saccharomyces cerevisiae: a role for isoprene modifications in ligand presentation.
Biochemistry 1997;36(40):12036-44.
1997: M A Lubkowitz; L Hauser; M Breslav; Fred Naider; Jeffrey M Becker
An oligopeptide transport gene from Candida albicans.
Microbiology (Reading, England) 1997;143 ( Pt 2)():387-96.
1997: Fred Naider; Jeffrey M Becker
Synthesis of prenylated peptides and peptide esters.
Biopolymers 1997;43(1):3-14.
1996: Y L Zhang; Jeffrey M Becker; Fred Naider
Electrophoretic behavior of L- and D-alanine-scanning analogs of a yeast tridecapeptide pheromone in a fused-silica capillary.
Analytical biochemistry 1996;241(2):220-7.
1996: M Breslav; A McKinney; Jeffrey M Becker; Fred Naider
Preparation of radiolabeled peptides via an iodine exchange reaction.
Analytical biochemistry 1996;239(2):213-7.
1996: Y L Zhang; A L Dawe; Y Jiang; Jeffrey M Becker; Fred Naider
A superactive peptidomimetic analog of a farnesylated dodecapeptide yeast pheromone.
Biochemical and biophysical research communications 1996;224(2):327-31.
1996: C B Xue; A McKinney; H F Lu; Y Jiang; Jeffrey M Becker; Fred Naider
Probing the functional conformation of the tridecapeptide mating pheromone of Saccharomyces cerevisiae through study of disulfide-constrained analogs.
International journal of peptide and protein research 1996;47(3):131-41.
1995: G A Caldwell; Fred Naider; Jeffrey M Becker
Fungal lipopeptide mating pheromones: a model system for the study of protein prenylation.
Microbiological reviews 1995;59(3):406-22.
1995: H Y Steiner; Fred Naider; Jeffrey M Becker
The PTR family: a new group of peptide transporters.
Molecular microbiology 1995;16(5):825-34.
1995: M A Basrai; M A Lubkowitz; J R Perry; D Miller; E Krainer; Fred Naider; Jeffrey M Becker
Cloning of a Candida albicans peptide transport gene.
Microbiology (Reading, England) 1995;141 ( Pt 5)():1147-56.
1995: M H Rao; W Yang; H Joshua; Jeffrey M Becker; Fred Naider
Studies on conformational consequences of i to i + 3 side-chain cyclization in model cyclic tetrapeptides.
International journal of peptide and protein research 1995;45(5):418-29.
1995: Y Jiang; M Breslav; R K Khare; A McKinney; Jeffrey M Becker; Fred Naider
Synthesis of alpha-factor analogues containing photoactivatable and labeling groups.
International journal of peptide and protein research 1995;45(2):106-15.
1995: W Yang; A McKinney; Jeffrey M Becker; Fred Naider
Systematic analysis of the Saccharomyces cerevisiae alpha-factor containing lactam constraints of different ring size.
Biochemistry 1995;34(4):1308-15.
1994: E Krainer; Ruth E Stark; Fred Naider; K Alagramam; Jeffrey M Becker
Direct observation of cell wall glucans in whole cells of Saccharomyces cerevisiae by magic-angle spinning 13C-NMR.
Biopolymers 1994;34(12):1627-35.
1994: J R Garbow; M Breslav; O Antohi; Fred Naider
Conformational analysis of the Saccharomyces cerevisiae tridecapeptide mating pheromone by 13C,15N rotational-echo double resonance nuclear magnetic resonance spectroscopy.
Biochemistry 1994;33(33):10094-9.
1994: G A Caldwell; S H Wang; C B Xue; Y Jiang; H F Lu; Fred Naider; Jeffrey M Becker
Molecular determinants of bioactivity of the Saccharomyces cerevisiae lipopeptide mating pheromone.
The Journal of biological chemistry 1994;269(31):19817-25.
1994: J S Gounarides; C B Xue; Jeffrey M Becker; Fred Naider
NMR investigation of cyclo7,10[C7,X9,C10,Nle12] analogues of the alpha-factor from Saccharomyces cerevisiae.
Biopolymers 1994;34(6):709-20.
1994: A P Reddy; M A Tallon; Jeffrey M Becker; Fred Naider
Biophysical studies on fragments of the alpha-factor receptor protein.
Biopolymers 1994;34(5):679-89.
1994: S H Wang; C B Xue; O Nielsen; J Davey; Fred Naider
Chemical synthesis of the M-factor mating pheromone from Schizosaccharomyces pombe.
Yeast (Chichester, England) 1994;10(5):595-601.
1994: G A Caldwell; S H Wang; Fred Naider; Jeffrey M Becker
Consequences of altered isoprenylation targets on a-factor export and bioactivity.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1275-9.
1994: J R Perry; M A Basrai; H Y Steiner; Fred Naider; Jeffrey M Becker
Isolation and characterization of a Saccharomyces cerevisiae peptide transport gene.
Molecular and cellular biology 1994;14(1):104-15.
1993: G A Caldwell; S H Wang; A L Dawe; Fred Naider; Jeffrey M Becker
Identification of a hyperactive mating pheromone of Saccharomyces cerevisiae.
Biochemical and biophysical research communications 1993;197(3):1173-8.
1993: Y Levin; R K Khare; G Abel; D Hill; E Eriotou-Bargiota; Jeffrey M Becker; Fred Naider
Histidine2 of the alpha-factor of Saccharomyces cerevisiae is not essential for binding to its receptor or for biological activity.
Biochemistry 1993;32(32):8199-206.
1993: M Tallon; D Ron; David Halle; Pietro Amodeo; Gabriella Saviano; Piero A Temussi; Zvi Selinger; Fred Naider; Michael Chorev
Synthesis, biological activity, and conformational analysis of [pGlu6,N-MePhe8,Aib9] substance P (6-11): a selective agonist for the NK-3 receptor.
Biopolymers 1993;33(6):915-26.
1993: J S Gounarides; M S Broido; Jeffrey M Becker; Fred Naider
Conformational analysis of [D-Ala9]alpha-factor and [L-Ala9]alpha-factor in solution and in the presence of lipid.
Biochemistry 1993;32(3):908-17.
1992: M A Basrai; H L Zhang; D Miller; Fred Naider; Jeffrey M Becker
Toxicity of oxalysine and oxalysine-containing peptides against Candida albicans: regulation of peptide transport by amino acids.
Journal of general microbiology 1992;138(11):2353-62.
1992: Fred Naider; J Gounarides; C B Xue; E Bargiota; Jeffrey M Becker
Studies on the yeast alpha-mating factor: a model for mammalian peptide hormones.
Biopolymers 1992;32(4):335-9.
1992: E Eriotou-Bargiota; C B Xue; Fred Naider; Jeffrey M Becker
Antagonistic and synergistic peptide analogues of the tridecapeptide mating pheromone of Saccharomyces cerevisiae.
Biochemistry 1992;31(2):551-7.
1992: H Zheng; H L Zhang; Jeffrey M Becker; Fred Naider; W R Farkas
The lysine analog L-oxalysine is an inhibitor of RNA synthesis.
The International journal of biochemistry 1992;24(1):145-9.
1991: J S Gounarides; M S Broido; C B Xue; Jeffrey M Becker; Fred Naider
The conformation of a-factor is not influenced by the S-prenylation of Cys12.
Biochemical and biophysical research communications 1991;181(3):1125-30.
1991: S Marcus; G A Caldwell; D Miller; C B Xue; Fred Naider; Jeffrey M Becker
Significance of C-terminal cysteine modifications to the biological activity of the Saccharomyces cerevisiae a-factor mating pheromone.
Molecular and cellular biology 1991;11(7):3603-12.
1991: C B Xue; Jeffrey M Becker; Fred Naider
Synthesis of S-alkyl and C-terminal analogs of the Saccharomyces cerevisiae a-factor. Influence of temperature on the stability of Fmoc and OFm groups toward HF.
International journal of peptide and protein research 1991;37(6):476-86.
1991: S Marcus; C B Xue; Fred Naider; Jeffrey M Becker
Degradation of a-factor by a Saccharomyces cerevisiae alpha-mating-type-specific endopeptidase: evidence for a role in recovery of cells from G1 arrest.
Molecular and cellular biology 1991;11(2):1030-9.
1991: E Krainer; Jeffrey M Becker; Fred Naider
Synthesis and biological evaluation of dipeptidyl and tripeptidyl polyoxin and nikkomycin analogues as anticandidal prodrugs.
Journal of medicinal chemistry 1991;34(1):174-80.
1990: S Marcus; G A Caldwell; C B Xue; Fred Naider; Jeffrey M Becker
Total in vitro maturation of the Saccharomyces cerevisiae a-factor lipopeptide mating pheromone.
Biochemical and biophysical research communications 1990;172(3):1310-6.
1990: C B Xue; Ariel Ewenson; Jeffrey M Becker; Fred Naider
Solution phase synthesis of Saccharomyces cerevisiae a-mating factor and its analogs.
International journal of peptide and protein research 1990;36(4):362-73.
1990: E Krainer; Fred Naider; Jeffrey M Becker
Conformational studies of nikkomycin X in aqueous solution.
Biopolymers 1990;29(8-9):1297-306.
1990: M A Basrai; Fred Naider; Jeffrey M Becker
Internalization of lucifer yellow in Candida albicans by fluid phase endocytosis.
Journal of general microbiology 1990;136(6):1059-65.
1990: Ariel Ewenson; S Marcus; Jeffrey M Becker; Fred Naider
Synthesis of biologically active analogs of the dodecapeptide a-factor mating pheromone of Saccharomyces cerevisiae.
International journal of peptide and protein research 1990;35(3):241-8.
1990: M A Castiglione-Morelli; F Lelj; Fred Naider; M Tallon; Teodorico Tancredi; Piero A Temussi
Conformation-activity relationship of sweet molecules. Comparison of aspartame and naphthimidazolesulfonic acids.
Journal of medicinal chemistry 1990;33(2):514-20.
1990: Fred Naider; A Yaron; Ariel Ewenson; M Tallon; C B Xue; J V Srinivasan; E Eriotou-Bargiota; Jeffrey M Becker
Synthetic probes for the alpha-factor receptor.
Biopolymers 1990;29(1):237-45.
1989: C B Xue; E Eriotou-Bargiota; D Miller; Jeffrey M Becker; Fred Naider
A covalently constrained congener of the Saccharomyces cerevisiae tridecapeptide mating pheromone is an agonist.
The Journal of biological chemistry 1989;264(32):19161-8.
1989: C B Xue; G A Caldwell; Jeffrey M Becker; Fred Naider
Total synthesis of the lipopeptide a-mating factor of Saccharomyces cerevisiae.
Biochemical and biophysical research communications 1989;162(1):253-7.
1989: Linda Jelicks; M S Broido; Jeffrey M Becker; Fred Naider
Interaction of the Saccharomyces cerevisiae alpha-factor with phospholipid vesicles as revealed by proton and phosphorus NMR.
Biochemistry 1989;28(10):4233-40.
1989: Fred Naider; Linda Jelicks; Jeffrey M Becker; M S Broido
Biologically significant conformation of the Saccharomyces cerevisiae alpha-factor.
Biopolymers 1989;28(1):487-97.
1988: S K Raths; Fred Naider; Jeffrey M Becker
Peptide analogues compete with the binding of alpha-factor to its receptor in Saccharomyces cerevisiae.
The Journal of biological chemistry 1988;263(33):17333-41.
1988: Linda Jelicks; Fred Naider; P Shenbagamurthi; Jeffrey M Becker; M S Broido
A type II beta-turn in a flexible peptide: proton assignment and conformational analysis of the alpha-factor from Saccharomyces cerevisiae in solution.
Biopolymers 1988;27(3):431-49.
1988: R K Khare; Jeffrey M Becker; Fred Naider
Synthesis and anticandidal properties of polyoxin L analogues containing alpha-amino fatty acids.
Journal of medicinal chemistry 1988;31(3):650-6.
1988: Jeffrey M Becker; S Marcus; J Tallock; D Miller; E Krainer; R K Khare; Fred Naider
Use of the chitin-synthesis inhibitor nikkomycin to treat disseminated candidiasis in mice.
The Journal of infectious diseases 1988;157(1):212-4.
1987: M A Tallon; P Shenbagamurthi; S Marcus; Jeffrey M Becker; Fred Naider
Synthesis and biological activity of amino terminus extended analogues of the alpha mating factor of Saccharomyces cerevisiae.
Biochemistry 1987;26(24):7767-74.
1987: Jeffrey M Becker; S Marcus; B Kundu; P Shenbagamurthi; Fred Naider
Towards determination of the structure of the Saccharomyces cerevisiae a-factor: an acylated pentadecapeptide blocks a-factor activity.
Molecular and cellular biology 1987;7(11):4122-4.
1987: E Krainer; R K Khare; Fred Naider; Jeffrey M Becker
Chemochromatography: its use for the separation of nikkomycins X and Z.
Analytical biochemistry 1987;160(1):233-9.
1986: P Shenbagamurthi; H A Smith; Jeffrey M Becker; Fred Naider
Synthesis and biological properties of chitin synthetase inhibitors resistant to cellular peptidases.
Journal of medicinal chemistry 1986;29(5):802-9.
1986: H A Smith; P Shenbagamurthi; Fred Naider; B Kundu; Jeffrey M Becker
Hydrophobic polyoxins are resistant to intracellular degradation in Candida albicans.
Antimicrobial agents and chemotherapy 1986;29(1):33-9.
1985: P Shenbagamurthi; B Kundu; S Raths; Jeffrey M Becker; Fred Naider
Biological activity and conformational isomerism in position 9 analogues of the des-1-tryptophan,3-beta-cyclohexylalanine-alpha-factor from Saccharomyces cerevisiae.
Biochemistry 1985;24(25):7070-6.
1985: P Shenbagamurthi; B Kundu; Jeffrey M Becker; Fred Naider
Synthesis and biological activity of N epsilon-acyl derivatives of a Saccharomyces cerevisiae mating pheromone.
International journal of peptide and protein research 1985;25(2):187-96.
1983: Fred Naider; P Shenbagamurthi; A S Steinfeld; H A Smith; C Boney; Jeffrey M Becker
Synthesis and biological activity of tripeptidyl polyoxins as antifungal agents.
Antimicrobial agents and chemotherapy 1983;24(5):787-96.
1983: P Shenbagamurthi; H A Smith; Jeffrey M Becker; A Steinfeld; Fred Naider
Design of anticandidal agents: synthesis and biological properties of analogues of polyoxin L.
Journal of medicinal chemistry 1983;26(10):1518-22.
1983: Jeffrey M Becker; N L Covert; P Shenbagamurthi; A S Steinfeld; Fred Naider
Polyoxin D inhibits growth of zoopathogenic fungi.
Antimicrobial agents and chemotherapy 1983;23(6):926-9.