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Angus Nairn

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.8 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Phenomena

Phosphorylation

Chemicals & Drugs

Living Beings

Genes & Molecular Sequences

Amino Acid Sequence

Concepts & Ideas

Molecular Sequence Data

Anatomy

Physiology

Signal Transduction

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Publications

TOP 3
Zhou Mingming; Rebholz Heike; Brocia Christine; Warner-Schmidt Jennifer L; Fienberg Allen A; Nairn Angus C; Greengard Paul; Flajolet Marc
Forebrain overexpression of CK1delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD.
Goffin Darren; Ali Afia B; Rampersaud Nazir; Harkavyi Alexander; Fuchs Celine; Whitton Peter S; Nairn Angus C; Jovanovic Jasmina N
Dopamine-dependent tuning of striatal inhibitory synaptogenesis.
Davidson Heather; Wilson Abigail; Gray Robert D; Horsley Alex; Pringle Ian A; McLachlan Gerry; Nairn Angus C; Stearns Cordelia; Gibson James; Holder Emma; Jones Lisa; Doherty Ann; Coles Rebecca; Sumner-Jones Stephanie G; Wasowicz Marguerite; Manvell Michelle; Griesenbach Uta; Hyde Stephen C; Gill Deborah R; Davies Jane; Collie D David S; Alton Eric W F W; Porteous David J; Boyd A Christopher
An immunocytochemical assay to detect human CFTR expression following gene transfer.

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All Publications

2010: Zhou Mingming; Rebholz Heike; Brocia Christine; Warner-Schmidt Jennifer L; Fienberg Allen A; Nairn Angus C; Greengard Paul; Flajolet Marc
Forebrain overexpression of CK1delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(9):4401-6.
2010: Goffin Darren; Ali Afia B; Rampersaud Nazir; Harkavyi Alexander; Fuchs Celine; Whitton Peter S; Nairn Angus C; Jovanovic Jasmina N
Dopamine-dependent tuning of striatal inhibitory synaptogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(8):2935-50.
2009: Davidson Heather; Wilson Abigail; Gray Robert D; Horsley Alex; Pringle Ian A; McLachlan Gerry; Nairn Angus C; Stearns Cordelia; Gibson James; Holder Emma; Jones Lisa; Doherty Ann; Coles Rebecca; Sumner-Jones Stephanie G; Wasowicz Marguerite; Manvell Michelle; Griesenbach Uta; Hyde Stephen C; Gill Deborah R; Davies Jane; Collie D David S; Alton Eric W F W; Porteous David J; Boyd A Christopher
An immunocytochemical assay to detect human CFTR expression following gene transfer.
Molecular and cellular probes 2009;23(6):272-80.
2009: Hansen Christian; Howlin Jillian; Tengholm Anders; Dyachok Oleg; Vogel Wolfgang F; Nairn Angus C; Greengard Paul; Andersson Tommy
Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.
The Journal of biological chemistry 2009;284(40):27533-43.
2009: Rebholz Heike; Nishi Akinori; Liebscher Sabine; Nairn Angus C; Flajolet Marc; Greengard Paul
CK2 negatively regulates Galphas signaling.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):14096-101.
2009: Wu Judy Qiju; Guo Jessie Yanxiang; Tang Wanli; Yang Chih-Sheng; Freel Christopher D; Chen Chen; Nairn Angus C; Kornbluth Sally
PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation.
Nature cell biology 2009;11(5):644-51.
2009: Sakuma Megumi; Tanaka Emi; Taru Hidenori; Tomita Susumu; Gandy Sam; Nairn Angus C; Nakaya Tadashi; Yamamoto Tohru; Suzuki Toshiharu
Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP.
Journal of neurochemistry 2009;109(2):465-75.
2009: McAvoy Thomas; Zhou Ming-ming; Greengard Paul; Nairn Angus C
Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3531-6.
2009: Endo Shogo; Shutoh Fumihiro; Dinh Tung Le; Okamoto Takehito; Ikeda Toshio; Suzuki Michiyuki; Kawahara Shigenori; Yanagihara Dai; Sato Yamato; Yamada Kazuyuki; Sakamoto Toshiro; Kirino Yutaka; Hartell Nicholas A; Yamaguchi Kazuhiko; Itohara Shigeyoshi; Nairn Angus C; Greengard Paul; Nagao Soichi; Ito Masao
Dual involvement of G-substrate in motor learning revealed by gene deletion.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3525-30.
2009: Kim Yong; Teylan Merilee A; Baron Matthew; Sands Adam; Nairn Angus C; Greengard Paul
Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2915-20.
2009: Hirunsatit Rungnapa; George Elizabeth D; Lipska Barbara K; Elwafi Hani M; Sander Lisa; Yrigollen Carolyn M; Gelernter Joel; Grigorenko Elena L; Lappalainen Jaakko; Mane Shrikant; Nairn Angus C; Kleinman Joel E; Simen Arthur A
Twenty-one-base-pair insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter activity.
Pharmacogenetics and genomics 2009;19(1):53-65.
2009: Cheng Lina; Pilder Stephen; Nairn Angus C; Ramdas Shandilya; Vijayaraghavan Srinivasan
PP1gamma2 and PPP1R11 are parts of a multimeric complex in developing testicular germ cells in which their steady state levels are reciprocally related.
PloS one 2009;4(3):e4861.
2008: Flajolet Marc; Wang Zhongfeng; Futter Marie; Shen Weixing; Nuangchamnong Nina; Bendor Jacob; Wallach Iwona; Nairn Angus C; Surmeier D James; Greengard Paul
FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity.
Nature neuroscience 2008;11(12):1402-9.
2008: Dancheck Barbara; Nairn Angus C; Peti Wolfgang
Detailed structural characterization of unbound protein phosphatase 1 inhibitors.
Biochemistry 2008;47(47):12346-56.
2008: Meyer Douglas A; Richer Edmond; Benkovic Stanley A; Hayashi Kanehiro; Kansy Janice W; Hale Carly F; Moy Lily Y; Kim Yong; O'Callaghan James P; Tsai Li-Huei; Greengard Paul; Nairn Angus C; Cowan Christopher W; Miller Diane B; Antich Pietro; Bibb James A
Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18561-6.
2008: Pulipparacharuvil Suprabha; Renthal William; Hale Carly F; Taniguchi Makoto; Xiao Guanghua; Kumar Arvind; Russo Scott J; Sikder Devanjan; Dewey Colleen M; Davis Maya M; Greengard Paul; Nairn Angus C; Nestler Eric J; Cowan Christopher W
Cocaine regulates MEF2 to control synaptic and behavioral plasticity.
Neuron 2008;59(4):621-33.
2008: Han Xiao-Jian; Lu Yun-Fei; Li Shun-Ai; Kaitsuka Taku; Sato Yasufumi; Tomizawa Kazuhito; Nairn Angus C; Takei Kohji; Matsui Hideki; Matsushita Masayuki
CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology.
The Journal of cell biology 2008;182(3):573-85.
2008: Flynn Maxfield P; Maizels Evelyn T; Karlsson Amelia B; McAvoy Thomas; Ahn Jung-Hyuck; Nairn Angus C; Hunzicker-Dunn Mary
Luteinizing hormone receptor activation in ovarian granulosa cells promotes protein kinase A-dependent dephosphorylation of microtubule-associated protein 2D.
Molecular endocrinology (Baltimore, Md.) 2008;22(7):1695-710.
2008: Stipanovich Alexandre; Valjent Emmanuel; Matamales Miriam; Nishi Akinori; Ahn Jung-Hyuck; Maroteaux Matthieu; Bertran-Gonzalez Jesus; Brami-Cherrier Karen; Enslen Hervé; Corbillé Anne-Gaëlle; Filhol Odile; Nairn Angus C; Greengard Paul; Hervé Denis; Girault Jean-Antoine
A phosphatase cascade by which rewarding stimuli control nucleosomal response.
Nature 2008;453(7197):879-84.
2008: Muly E Chris; Nairn Angus C; Greengard Paul; Rainnie Donald G
Subcellular distribution of the Rho-GEF Lfc in primate prefrontal cortex: effect of neuronal activation.
The Journal of comparative neurology 2008;508(6):927-39.
2008: Sung Jee Young; Engmann Olivia; Teylan Merilee A; Nairn Angus C; Greengard Paul; Kim Yong
WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(8):3112-6.
2007: Barbano Paolo E; Spivak Marina; Flajolet Marc; Nairn Angus C; Greengard Paul; Greengard Leslie
A mathematical tool for exploring the dynamics of biological networks.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19169-74.
2007: Krueger Dilja D; Nairn Angus C
Expression of PKC substrate proteins, GAP-43 and neurogranin, is downregulated by cAMP signaling and alterations in synaptic activity.
The European journal of neuroscience 2007;26(11):3043-53.
2007: Olausson Peter; Jentsch J David; Krueger Dilja D; Tronson Natalie C; Nairn Angus C; Taylor Jane R
Orbitofrontal cortex and cognitive-motivational impairments in psychostimulant addiction: evidence from experiments in the non-human primate.
Annals of the New York Academy of Sciences 2007;1121():610-38.
2007: Kimura Tohru; Allen Patrick B; Nairn Angus C; Caplan Michael J
Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase.
Molecular biology of the cell 2007;18(11):4508-18.
2007: Ju Tingting; Ragusa Michael J; Hudak Jebecka; Nairn Angus C; Peti Wolfgang
Structural characterization of the neurabin sterile alpha motif domain.
Proteins 2007;69(1):192-8.
2007: Piccoli Giovanni; Verpelli Chiara; Tonna Noemi; Romorini Stefano; Alessio Massimo; Nairn Angus C; Bachi Angela; Sala Carlo
Proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons.
Journal of proteome research 2007;6(8):3203-15.
2007: Andrade Erika C; Krueger Dilja D; Nairn Angus C
Recent advances in neuroproteomics.
Current opinion in molecular therapeutics 2007;9(3):270-81.
2007: Matsuzaki Hideo; Minabe Yoshio; Nakamura Kazuhiko; Suzuki Katsuaki; Iwata Yasuhide; Sekine Yoshimoto; Tsuchiya Kenji J; Sugihara Genichi; Suda Shiro; Takei Nori; Nakahara Daiichiro; Hashimoto Kenji; Nairn Angus C; Mori Norio; Sato Kohji
Disruption of reelin signaling attenuates methamphetamine-induced hyperlocomotion.
The European journal of neuroscience 2007;25(11):3376-84.
2007: Ahn Jung-Hyuck; Sung Jee Young; McAvoy Thomas; Nishi Akinori; Janssens Veerle; Goris Jozef; Greengard Paul; Nairn Angus C
The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9876-81.
2007: Nguyen Chan; Nishi Akinori; Kansy Janice W; Fernandez Joseph; Hayashi Kanehiro; Gillardon Frank; Hemmings Hugh C; Nairn Angus C; Bibb James A
Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5.
The Journal of biological chemistry 2007;282(22):16511-20.
2007: Uboha Nataliya V; Flajolet Marc; Nairn Angus C; Picciotto Marina R
A calcium- and calmodulin-dependent kinase Ialpha/microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite outgrowth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(16):4413-23.
2007: Flajolet Marc; He Gen; Heiman Myriam; Lin Angie; Nairn Angus C; Greengard Paul
Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):4159-64.
2007: Kelker Matthew S; Dancheck Barbara; Ju Tingting; Kessler Rene P; Hudak Jebecka; Nairn Angus C; Peti Wolfgang
Structural basis for spinophilin-neurabin receptor interaction.
Biochemistry 2007;46(9):2333-44.
2007: Ahn Jung-Hyuck; McAvoy Thomas; Rakhilin Sergey V; Nishi Akinori; Greengard Paul; Nairn Angus C
Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2979-84.
2007: Iizuka Akira; Sengoku Kumiko; Iketani Masumi; Nakamura Fumio; Sato Yasufumi; Matsushita Masayuki; Nairn Angus C; Takamatsu Ken; Goshima Yoshio; Takei Kohtaro
Calcium-induced synergistic inhibition of a translational factor eEF2 in nerve growth cones.
Biochemical and biophysical research communications 2007;353(2):244-50.
2007: Hotte Maïté; Thuault Sébastien; Dineley Kelly T; Hemmings Hugh C; Nairn Angus C; Jay Thérèse M
Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo.
Synapse (New York, N.Y.) 2007;61(1):24-8.
2006: Kanhema Tambudzai; Dagestad Grethe; Panja Debabrata; Tiron Adrian; Messaoudi Elhoucine; Håvik Bjarte; Ying Shui-Wang; Nairn Angus C; Sonenberg Nahum; Bramham Clive R
Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control.
Journal of neurochemistry 2006;99(5):1328-37.
2006: Hansen Christian; Greengard Paul; Nairn Angus C; Andersson Tommy; Vogel Wolfgang F
Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1.
Experimental cell research 2006;312(20):4011-8.
2006: Margolis Seth S; Perry Jennifer A; Forester Craig M; Nutt Leta K; Guo Yanxiang; Jardim Melanie J; Thomenius Michael J; Freel Christopher D; Darbandi Rashid; Ahn Jung-Hyuck; Arroyo Jason D; Wang Xiao-Fan; Shenolikar Shirish; Nairn Angus C; Dunphy William G; Hahn William C; Virshup David M; Kornbluth Sally
Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis.
Cell 2006;127(4):759-73.
2006: Csanády László; Nairn Angus C; Gadsby David C
Thermodynamics of CFTR channel gating: a spreading conformational change initiates an irreversible gating cycle.
The Journal of general physiology 2006;128(5):523-33.
2006: Krueger Dilja D; Howell Jessica L; Hebert Britni F; Olausson Peter; Taylor Jane R; Nairn Angus C
Assessment of cognitive function in the heterozygous reeler mouse.
Psychopharmacology 2006;189(1):95-104.
2006: Mense Martin; Vergani Paola; White Dennis M; Altberg Gal; Nairn Angus C; Gadsby David C
In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer.
The EMBO journal 2006;25(20):4728-39.
2006: Kim Yong; Sung Jee Young; Ceglia Ilaria; Lee Ko-Woon; Ahn Jung-Hyuck; Halford Jonathan M; Kim Amie M; Kwak Seung P; Park Jong Bae; Ho Ryu Sung; Schenck Annette; Bardoni Barbara; Scott John D; Nairn Angus C; Greengard Paul
Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology.
Nature 2006;442(7104):814-7.
2006: Braithwaite Steven P; Paul Surojit; Nairn Angus C; Lombroso Paul J
Synaptic plasticity: one STEP at a time.
Trends in neurosciences 2006;29(8):452-8.
2006: Sahin Bogachan; Shu Hongjun; Fernandez Joseph; El-Armouche Ali; Molkentin Jeffery D; Nairn Angus C; Bibb James A
Phosphorylation of protein phosphatase inhibitor-1 by protein kinase C.
The Journal of biological chemistry 2006;281(34):24322-35.
2006: Hotte Maïté; Thuault Sébastien; Lachaise Fabienne; Dineley Kelly T; Hemmings Hugh C; Nairn Angus C; Jay Thérèse M
D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex.
Behavioural brain research 2006;171(1):127-33.
2006: Zhang Y; Svenningsson P; Picetti R; Schlussman S D; Nairn A C; Ho A; Greengard P; Kreek M J
Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(10):2645-51.
2006: Rogers Jessica P; Beuscher Albert E; Flajolet Marc; McAvoy Thomas; Nairn Angus C; Olson Arthur J; Greengard Paul
Discovery of protein phosphatase 2C inhibitors by virtual screening.
Journal of medicinal chemistry 2006;49(5):1658-67.
2006: Zachariou Venetia; Sgambato-Faure Véronique; Sasaki Teresa; Svenningsson Per; Berton Olivier; Fienberg Allen A; Nairn Angus C; Greengard Paul; Nestler Eric J
Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(3):555-62.
2006: Lee Ko-Woon; Kim Yong; Kim Amie M; Helmin Kathryn; Nairn Angus C; Greengard Paul
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3399-404.
2006: Rosenberg Oren S; Deindl Sebastian; Comolli Luis R; Hoelz André; Downing Kenneth H; Nairn Angus C; Kuriyan John
Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II.
The FEBS journal 2006;273(4):682-94.
2006: Maus M; Torrens Y; Gauchy C; Bretin S; Nairn A C; Glowinski J; Premont J
2-Deoxyglucose and NMDA inhibit protein synthesis in neurons and regulate phosphorylation of elongation factor-2 by distinct mechanisms.
Journal of neurochemistry 2006;96(3):815-24.
2006: Scott Lena; Zelenin Sergey; Malmersjö Seth; Kowalewski Jacob M; Markus Eivor Zettergren; Nairn Angus C; Greengard Paul; Brismar Hjalmar; Aperia Anita
Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(3):762-7.
2005: Jin Mi; Bateup Helen; Padovan Júlio C; Greengard Paul; Nairn Angus C; Chait Brian T
Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry.
Analytical chemistry 2005;77(24):7845-51.
2005: Rosenberg Oren S; Deindl Sebastian; Sung Rou-Jia; Nairn Angus C; Kuriyan John
Structure of the autoinhibited kinase domain of CaMKII and SAXS analysis of the holoenzyme.
Cell 2005;123(5):849-60.
2005: Uematsu Ken; Futter Marie; Hsieh-Wilson Linda C; Higashi Hideho; Maeda Hisao; Nairn Angus C; Greengard Paul; Nishi Akinori
Regulation of spinophilin Ser94 phosphorylation in neostriatal neurons involves both DARPP-32-dependent and independent pathways.
Journal of neurochemistry 2005;95(6):1642-52.
2005: Bordelon Jill R; Smith Yoland; Nairn Angus C; Colbran Roger J; Greengard Paul; Muly E Chris
Differential localization of protein phosphatase-1alpha, beta and gamma1 isoforms in primate prefrontal cortex.
Cerebral cortex (New York, N.Y. : 1991) 2005;15(12):1928-37.
2005: Kozak J Ashot; Matsushita Masayuki; Nairn Angus C; Cahalan Michael D
Charge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels.
The Journal of general physiology 2005;126(5):499-514.
2005: Yeshao Wen; Gu Jiali; Peng Xianghong; Nairn Angus C; Nadler Jerry L
Elevated glucose activates protein synthesis in cultured cardiac myocytes.
Metabolism: clinical and experimental 2005;54(11):1453-60.
2005: Vergani P; Basso C; Mense M; Nairn A C; Gadsby D C
Control of the CFTR channel's gates.
Biochemical Society transactions 2005;33(Pt 5):1003-7.
2005: Hamada Miho; Hendrick Joseph P; Ryan Gregory R; Kuroiwa Mahomi; Higashi Hideho; Tanaka Masatoshi; Nairn Angus C; Greengard Paul; Nishi Akinori
Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons.
The Journal of pharmacology and experimental therapeutics 2005;315(2):872-8.
2005: Snyder Eric M; Nong Yi; Almeida Claudia G; Paul Surojit; Moran Timothy; Choi Eun Young; Nairn Angus C; Salter Michael W; Lombroso Paul J; Gouras Gunnar K; Greengard Paul
Regulation of NMDA receptor trafficking by amyloid-beta.
Nature neuroscience 2005;8(8):1051-8.
2005: Ryan Xiaozhou P; Alldritt Jacqueline; Svenningsson Per; Allen Patrick B; Wu Gang-Yi; Nairn Angus C; Greengard Paul
The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology.
Neuron 2005;47(1):85-100.
2005: Matsushita Masayuki; Kozak J Ashot; Shimizu Yoshio; McLachlin Derek T; Yamaguchi Hiroto; Wei Fan-Yan; Tomizawa Kazuhito; Matsui Hideki; Chait Brian T; Cahalan Michael D; Nairn Angus C
Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1.
The Journal of biological chemistry 2005;280(21):20793-803.
2005: Hilfiker Sabine; Benfenati Fabio; Doussau Frédéric; Nairn Angus C; Czernik Andrew J; Augustine George J; Greengard Paul
Structural domains involved in the regulation of transmitter release by synapsins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(10):2658-69.
2005: Futter Marie; Uematsu Ken; Bullock Stewart A; Kim Yong; Hemmings Hugh C; Nishi Akinori; Greengard Paul; Nairn Angus C
Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3489-94.
2005: Lee Sang Yoon; Voronov Sergey; Letinic Kresimir; Nairn Angus C; Di Paolo Gilbert; De Camilli Pietro
Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases.
The Journal of cell biology 2005;168(5):789-99.
2005: Vergani Paola; Lockless Steve W; Nairn Angus C; Gadsby David C
CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains.
Nature 2005;433(7028):876-80.
2005: Takahashi Satoru; Ohshima Toshio; Cho Andrew; Sreenath Taduru; Iadarola Michael J; Pant Harish C; Kim Yong; Nairn Angus C; Brady Roscoe O; Greengard Paul; Kulkarni Ashok B
Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1737-42.
2005: Csanády László; Seto-Young Donna; Chan Kim W; Cenciarelli Cristina; Angel Benjamin B; Qin Jun; McLachlin Derek T; Krutchinsky Andrew N; Chait Brian T; Nairn Angus C; Gadsby David C
Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA.
The Journal of general physiology 2005;125(2):171-86.
2005: Nishi Akinori; Watanabe Yasuo; Higashi Hideho; Tanaka Masatoshi; Nairn Angus C; Greengard Paul
Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(4):1199-204.
2005: Valjent Emmanuel; Pascoli Vincent; Svenningsson Per; Paul Surojit; Enslen Hervé; Corvol Jean-Christophe; Stipanovich Alexandre; Caboche Jocelyne; Lombroso Paul J; Nairn Angus C; Greengard Paul; Hervé Denis; Girault Jean-Antoine
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):491-6.
2005: Csanády László; Chan Kim W; Nairn Angus C; Gadsby David C
Functional roles of nonconserved structural segments in CFTR's NH2-terminal nucleotide binding domain.
The Journal of general physiology 2005;125(1):43-55.
2005: Svenningsson Per; Nairn Angus C; Greengard Paul
DARPP-32 mediates the actions of multiple drugs of abuse.
The AAPS journal 2005;7(2):E353-60.
2004: Rakhilin S V; Olson P A; Nishi A; Starkova N N; Fienberg A A; Nairn A C; Surmeier D J; Greengard P
A network of control mediated by regulator of calcium/calmodulin-dependent signaling.
Science (New York, N.Y.) 2004;306(5696):698-701.
2004: Sahin Bogachan; Kansy Janice W; Nairn Angus C; Spychala Jozef; Ealick Steven E; Fienberg Allen A; Greene Robert W; Bibb James A
Molecular characterization of recombinant mouse adenosine kinase and evaluation as a target for protein phosphorylation.
European journal of biochemistry / FEBS 2004;271(17):3547-55.
2004: Hamada Miho; Higashi Hideho; Nairn Angus C; Greengard Paul; Nishi Akinori
Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons.
Journal of neurochemistry 2004;90(5):1094-103.
2004: Grossman Stacie D; Futter Marie; Snyder Gretchen L; Allen Patrick B; Nairn Angus C; Greengard Paul; Hsieh-Wilson Linda C
Spinophilin is phosphorylated by Ca2+/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin.
Journal of neurochemistry 2004;90(2):317-24.
2004: Stedman Diann R; Uboha Nataliya V; Stedman Timothy T; Nairn Angus C; Picciotto Marina R
Cytoplasmic localization of calcium/calmodulin-dependent protein kinase I-alpha depends on a nuclear export signal in its regulatory domain.
FEBS letters 2004;566(1-3):275-80.
2004: Vary Thomas C; Nairn Angus C; Lang Charles H
Restoration of protein synthesis in heart and skeletal muscle after withdrawal of alcohol.
Alcoholism, clinical and experimental research 2004;28(4):517-25.
2004: Lin Ta-Hsien; Huang Yi-Choang; Chin Mei-ling; Chen Yi-chen; Jeng Hao-Hsuan; Lin Fang-Min; Shiao Ming-Shi; Horiuchi Atsuko; Greengard Paul; Nairn Angus C; Huang Hsien-bin
1H, 15N, and 13C resonance assignments of DARPP-32 (dopamine and cAMP-regulated phosphoprotein, Mr. 32,000)--a protein inhibitor of protein phosphatase-1.
Journal of biomolecular NMR 2004;28(4):413-4.
2004: Braz Julian C; Gregory Kimberly; Pathak Anand; Zhao Wen; Sahin Bogachan; Klevitsky Raisa; Kimball Thomas F; Lorenz John N; Nairn Angus C; Liggett Stephen B; Bodi Ilona; Wang Su; Schwartz Arnold; Lakatta Edward G; DePaoli-Roach Anna A; Robbins Jeffrey; Hewett Timothy E; Bibb James A; Westfall Margaret V; Kranias Evangelia G; Molkentin Jeffery D
PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Nature medicine 2004;10(3):248-54.
2004: Lee Sang Yoon; Wenk Markus R; Kim Yong; Nairn Angus C; De Camilli Pietro
Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):546-51.
2004: Williams Kenneth; Wu Terence; Colangelo Christopher; Nairn Angus C
Recent advances in neuroproteomics and potential application to studies of drug addiction.
Neuropharmacology 2004;47 Suppl 1():148-66.
2004: Nairn Angus C; Svenningsson Per; Nishi Akinori; Fisone Gilberto; Girault Jean-Antoine; Greengard Paul
The role of DARPP-32 in the actions of drugs of abuse.
Neuropharmacology 2004;47 Suppl 1():14-23.
2004: Svenningsson Per; Nishi Akinori; Fisone Gilberto; Girault Jean-Antoine; Nairn Angus C; Greengard Paul
DARPP-32: an integrator of neurotransmission.
Annual review of pharmacology and toxicology 2004;44():269-96.
2003: Fukui Ryuichi; Svenningsson Per; Matsuishi Toyojiro; Higashi Hideho; Nairn Angus C; Greengard Paul; Nishi Akinori
Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice.
Journal of neurochemistry 2003;87(6):1391-401.
2003: Flajolet Marc; Rakhilin Sergey; Wang Hong; Starkova Natalia; Nuangchamnong Nina; Nairn Angus C; Greengard Paul
Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):16006-11.
2003: Snyder Gretchen L; Galdi Stacey; Fienberg Allen A; Allen Patrick; Nairn Angus C; Greengard Paul
Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists.
Neuropharmacology 2003;45(6):703-13.
2003: Basso Claudia; Vergani Paola; Nairn Angus C; Gadsby David C
Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating.
The Journal of general physiology 2003;122(3):333-48.
2003: Sgambato Véronique; Minassian Raia; Nairn Angus C; Hyman Steven E
Regulation of ania-6 splice variants by distinct signaling pathways in striatal neurons.
Journal of neurochemistry 2003;86(1):153-64.
2003: Hoelz André; Nairn Angus C; Kuriyan John
Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II.
Molecular cell 2003;11(5):1241-51.
2003: Colby David A; Liu Wen; Sheppeck James E; Huang Hsien Bin; Nairn Angus C; Chamberlin A Richard
A new model of the tautomycin-PP1 complex that is not analogous to the corresponding okadaic acid structure.
Bioorganic & medicinal chemistry letters 2003;13(9):1601-5.
2003: Liu Wen; Sheppeck James E; Colby David A; Huang Hsien-Bin; Nairn Angus C; Chamberlin A Richard
The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity.
Bioorganic & medicinal chemistry letters 2003;13(9):1597-600.
2003: Yan Limei; Nairn Angus C; Palfrey H Clive; Brady Matthew J
Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells.
The Journal of biological chemistry 2003;278(20):18177-83.
2003: Kim Young-Mi; Watanabe Takuo; Allen Patrick B; Kim Young-Myoung; Lee Shin-Jeong; Greengard Paul; Nairn Angus C; Kwon Young-Guen
PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation.
The Journal of biological chemistry 2003;278(16):13819-28.
2003: Nishi Akinori; Liu Feng; Matsuyama Seiichiro; Hamada Miho; Higashi Hideho; Nairn Angus C; Greengard Paul
Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1322-7.
2003: Vergani Paola; Nairn Angus C; Gadsby David C
On the mechanism of MgATP-dependent gating of CFTR Cl- channels.
The Journal of general physiology 2003;121(1):17-36.
2003: Endo Shogo; Nairn Angus C; Greengard Paul; Ito Masao
Thr123 of rat G-substrate contributes to its action as a protein phosphatase inhibitor.
Neuroscience research 2003;45(1):79-89.
2003: Paul Surojit; Nairn Angus C; Wang Ping; Lombroso Paul J
NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling.
Nature neuroscience 2003;6(1):34-42.
2003: Hsieh-Wilson Linda C; Benfenati Fabio; Snyder Gretchen L; Allen Patrick B; Nairn Angus C; Greengard Paul
Phosphorylation of spinophilin modulates its interaction with actin filaments.
The Journal of biological chemistry 2003;278(2):1186-94.
2003: Watanabe Takuo; da Cruz e Silva Edgar F; Huang Hsien-Bin; Starkova Natalia; Kwon Young-Guen; Horiuchi Atsuko; Greengard Paul; Nairn Angus C
Preparation and characterization of recombinant protein phosphatase 1.
Methods in enzymology 2003;366():321-38.
2002: Vary Thomas C; Nairn Angus C; Deiter Gina; Lang Charles H
Differential effects of alcohol consumption on eukaryotic elongation factors in heart, skeletal muscle, and liver.
Alcoholism, clinical and experimental research 2002;26(12):1794-802.
2002: Liu Feng; Virshup David M; Nairn Angus C; Greengard Paul
Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors.
The Journal of biological chemistry 2002;277(47):45393-9.
2002: Alirezaei Mehrdad; Mordelet Elodie; Rouach Nathalie; Nairn Angus C; Glowinski Jacques; Prémont Joël
Zinc-induced inhibition of protein synthesis and reduction of connexin-43 expression and intercellular communication in mouse cortical astrocytes.
The European journal of neuroscience 2002;16(6):1037-44.
2002: Irwin Nina; Chao Steven; Goritchenko Luda; Horiuchi Atsuko; Greengard Paul; Nairn Angus C; Benowitz Larry I
Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12427-31.
2002: Lindskog Maria; Svenningsson Per; Pozzi Laura; Kim Yong; Fienberg Allen A; Bibb James A; Fredholm Bertil B; Nairn Angus C; Greengard Paul; Fisone Gilberto
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine.
Nature 2002;418(6899):774-8.
2002: Feschenko Marina S; Stevenson Elizabeth; Nairn Angus C; Sweadner Kathleen J
A novel cAMP-stimulated pathway in protein phosphatase 2A activation.
The Journal of pharmacology and experimental therapeutics 2002;302(1):111-8.
2002: Dousmanis Athanasios G; Nairn Angus C; Gadsby David C
Distinct Mg(2+)-dependent steps rate limit opening and closing of a single CFTR Cl(-) channel.
The Journal of general physiology 2002;119(6):545-59.
2002: Nishi Akinori; Bibb James A; Matsuyama Seiichiro; Hamada Miho; Higashi Hideho; Nairn Angus C; Greengard Paul
Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A.
Journal of neurochemistry 2002;81(4):832-41.
2002: Kranz James K; Lee Eun K; Nairn Angus C; Wand A Joshua
A direct test of the reductionist approach to structural studies of calmodulin activity: relevance of peptide models of target proteins.
The Journal of biological chemistry 2002;277(19):16351-4.
2002: Pastorino Lucia; Ikin Annat F; Nairn Angus C; Pursnani Amit; Buxbaum Joseph D
The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta).
Molecular and cellular neurosciences 2002;19(2):175-85.
2002: Lang Charles H; Frost Robert A; Nairn Angus C; MacLean David A; Vary Thomas C
TNF-alpha impairs heart and skeletal muscle protein synthesis by altering translation initiation.
American journal of physiology. Endocrinology and metabolism 2002;282(2):E336-47.
2002: Gauchy C; Nairn A C; Glowinski J; Prémont J
N-Methyl-D-aspartate receptor activation inhibits protein synthesis in cortical neurons independently of its ionic permeability properties.
Neuroscience 2002;114(4):859-67.
2002: Grossman Stacie D; Hsieh-Wilson Linda C; Allen Patrick B; Nairn Angus C; Greengard Paul
The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines.
Neuromolecular medicine 2002;2(1):61-9.
2001: Nairn A C; Greengard P
A novel cyclin provides a link between dopamine and RNA processing.
Neuron 2001;32(2):174-6.
2001: Jovanovic J N; Sihra T S; Nairn A C; Hemmings H C; Greengard P; Czernik A J
Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(20):7944-53.
2001: Liu F; Ma X H; Ule J; Bibb J A; Nishi A; DeMaggio A J; Yan Z; Nairn A C; Greengard P
Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11062-8.
2001: Chen Y; Matsushita M; Nairn A C; Damuni Z; Cai D; Frerichs K U; Hallenbeck J M
Mechanisms for increased levels of phosphorylation of elongation factor-2 during hibernation in ground squirrels.
Biochemistry 2001;40(38):11565-70.
2001: Everett A D; Stoops T D; Nairn A C; Brautigan D
Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes.
American journal of physiology. Heart and circulatory physiology 2001;281(1):H161-7.
2001: Huang H B; Chen Y C; Horiuchi A; Tsai L H; Liu H T; Chyan C L; Hsieh M J; Liu C K; Lin F M; Greengard P; Nairn A C; Shiao M S; Lin T H
Backbone 1H, 15N, and 13C resonance assignments of ARPP-19.
Journal of biomolecular NMR 2001;19(4):383-4.
2001: Dulubova I; Horiuchi A; Snyder G L; Girault J A; Czernik A J; Shao L; Ramabhadran R; Greengard P; Nairn A C
ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins.
Journal of neurochemistry 2001;77(1):229-38.
2001: Bibb J A; Nishi A; O'Callaghan J P; Ule J; Lan M; Snyder G L; Horiuchi A; Saito T; Hisanaga S; Czernik A J; Nairn A C; Greengard P
Phosphorylation of protein phosphatase inhibitor-1 by Cdk5.
The Journal of biological chemistry 2001;276(17):14490-7.
2001: Bibb J A; Chen J; Taylor J R; Svenningsson P; Nishi A; Snyder G L; Yan Z; Sagawa Z K; Ouimet C C; Nairn A C; Nestler E J; Greengard P
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.
Nature 2001;410(6826):376-80.
2001: Watanabe T; Huang H B; Horiuchi A; da Cruze Silva E F; Hsieh-Wilson L; Allen P B; Shenolikar S; Greengard P; Nairn A C
Protein phosphatase 1 regulation by inhibitors and targeting subunits.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3080-5.
2001: Alirezaei M; Marin P; Nairn A C; Glowinski J; Prémont J
Inhibition of protein synthesis in cortical neurons during exposure to hydrogen peroxide.
Journal of neurochemistry 2001;76(4):1080-8.
2001: Nairn A C; Matsushita M; Nastiuk K; Horiuchi A; Mitsui K; Shimizu Y; Palfrey H C
Elongation factor-2 phosphorylation and the regulation of protein synthesis by calcium.
Progress in molecular and subcellular biology 2001;27():91-129.
2000: Nishi A; Bibb J A; Snyder G L; Higashi H; Nairn A C; Greengard P
Amplification of dopaminergic signaling by a positive feedback loop.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12840-5.
2000: Csanády L; Chan K W; Seto-Young D; Kopsco D C; Nairn A C; Gadsby D C
Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains.
The Journal of general physiology 2000;116(3):477-500.
2000: Iijima K; Ando K; Takeda S; Satoh Y; Seki T; Itohara S; Greengard P; Kirino Y; Nairn A C; Suzuki T
Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5.
Journal of neurochemistry 2000;75(3):1085-91.
2000: Huang H B; Chen Y C; Tsai L H; Wang H; Lin F M; Horiuchi A; Greengard P; Nairn A C; Shiao M S; Lin T H
Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 -- a protein inhibitor of protein phosphatase-1.
Journal of biomolecular NMR 2000;17(4):359-60.
2000: Chan K W; Csanády L; Seto-Young D; Nairn A C; Gadsby D C
Severed molecules functionally define the boundaries of the cystic fibrosis transmembrane conductance regulator's NH(2)-terminal nucleotide binding domain.
The Journal of general physiology 2000;116(2):163-80.
2000: Paul S; Snyder G L; Yokakura H; Picciotto M R; Nairn A C; Lombroso P J
The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(15):5630-8.
2000: Caporaso G L; Bibb J A; Snyder G L; Valle C; Rakhilin S; Fienberg A A; Hemmings H C; Nairn A C; Greengard P
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia.
Neuropharmacology 2000;39(9):1637-44.
2000: Snyder G L; Allen P B; Fienberg A A; Valle C G; Huganir R L; Nairn A C; Greengard P
Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(12):4480-8.
2000: Bibb J A; Yan Z; Svenningsson P; Snyder G L; Pieribone V A; Horiuchi A; Nairn A C; Messer A; Greengard P
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6809-14.
2000: Connor J H; Frederick D; Huang H b; Yang J; Helps N R; Cohen P T; Nairn A C; DePaoli-Roach A; Tatchell K; Shenolikar S
Cellular mechanisms regulating protein phosphatase-1. A key functional interaction between inhibitor-2 and the type 1 protein phosphatase catalytic subunit.
The Journal of biological chemistry 2000;275(25):18670-5.
2000: Zelenina M; Christensen B M; Palmér J; Nairn A C; Nielsen S; Aperia A
Prostaglandin E(2) interaction with AVP: effects on AQP2 phosphorylation and distribution.
American journal of physiology. Renal physiology 2000;278(3):F388-94.
2000: Scheetz A J; Nairn A C; Constantine-Paton M
NMDA receptor-mediated control of protein synthesis at developing synapses.
Nature neuroscience 2000;3(3):211-6.
2000: Aggen J B; Nairn A C; Chamberlin R
Regulation of protein phosphatase-1.
Chemistry & biology 2000;7(1):R13-23.
1999: Bibb J A; Snyder G L; Nishi A; Yan Z; Meijer L; Fienberg A A; Tsai L H; Kwon Y T; Girault J A; Czernik A J; Huganir R L; Hemmings H C; Nairn A C; Greengard P
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.
Nature 1999;402(6762):669-71.
1999: Alirezaei M; Nairn A C; Glowinski J; Prémont J; Marin P
Zinc inhibits protein synthesis in neurons. Potential role of phosphorylation of translation initiation factor-2alpha.
The Journal of biological chemistry 1999;274(45):32433-8.
1999: Nishi A; Fisone G; Snyder G L; Dulubova I; Aperia A; Nairn A C; Greengard P
Regulation of Na+, K+-ATPase isoforms in rat neostriatum by dopamine and protein kinase C.
Journal of neurochemistry 1999;73(4):1492-501.
1999: Chung H; Nairn A C; Murata K; Brautigan D L
Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2.
Biochemistry 1999;38(32):10371-6.
1999: Greengard P; Allen P B; Nairn A C
Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade.
Neuron 1999;23(3):435-47.
1999: Nishi A; Snyder G L; Fienberg A A; Fisone G; Aperia A; Nairn A C; Greengard P
Requirement for DARPP-32 in mediating effect of dopamine D2 receptor activation.
The European journal of neuroscience 1999;11(7):2589-92.
1999: Ando K; Oishi M; Takeda S; Iijima K; Isohara T; Nairn A C; Kirino Y; Greengard P; Suzuki T
Role of phosphorylation of Alzheimer's amyloid precursor protein during neuronal differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(11):4421-7.
1999: Isohara T; Horiuchi A; Watanabe T; Ando K; Czernik A J; Uno I; Greengard P; Nairn A C; Suzuki T
Phosphorylation of the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein at Ser655 by a novel protein kinase.
Biochemical and biophysical research communications 1999;258(2):300-5.
1999: Nishi A; Snyder G L; Nairn A C; Greengard P
Role of calcineurin and protein phosphatase-2A in the regulation of DARPP-32 dephosphorylation in neostriatal neurons.
Journal of neurochemistry 1999;72(5):2015-21.
1999: Fienberg A A; Nordstedt C; Belting H G; Czernik A J; Nairn A C; Gandy S; Greengard P; Ruddle F H
Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6.
The Journal of experimental zoology 1999;285(1):76-84.
1999: Hsieh-Wilson L C; Allen P B; Watanabe T; Nairn A C; Greengard P
Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1.
Biochemistry 1999;38(14):4365-73.
1999: Matsushita M; Nairn A C
Inhibition of the Ca2+/calmodulin-dependent protein kinase I cascade by cAMP-dependent protein kinase.
The Journal of biological chemistry 1999;274(15):10086-93.
1999: Aggen J B; Humphrey J M; Gauss C M; Huang H B; Nairn A C; Chamberlin A R
The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity.
Bioorganic & medicinal chemistry 1999;7(3):543-64.
1999: Nishimoto G; Zelenina M; Li D; Yasui M; Aperia A; Nielsen S; Nairn A C
Arginine vasopressin stimulates phosphorylation of aquaporin-2 in rat renal tissue.
The American journal of physiology 1999;276(2 Pt 2):F254-9.
1999: Watanabe T; Sukegawa J; Sukegawa I; Tomita S; Iijima K; Oguchi S; Suzuki T; Nairn A C; Greengard P
A 127-kDa protein (UV-DDB) binds to the cytoplasmic domain of the Alzheimer's amyloid precursor protein.
Journal of neurochemistry 1999;72(2):549-56.
1999: Yan Z; Hsieh-Wilson L; Feng J; Tomizawa K; Allen P B; Fienberg A A; Nairn A C; Greengard P
Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin.
Nature neuroscience 1999;2(1):13-7.
1999: Gadsby D C; Nairn A C
Regulation of CFTR Cl- ion channels by phosphorylation and dephosphorylation.
Advances in second messenger and phosphoprotein research 1999;33():79-106.
1998: Gadsby D C; Dousmanis A G; Nairn A C
ATP hydrolysis cycles and the gating of CFTR Cl- channels.
Acta physiologica Scandinavica. Supplementum 1998;643():247-56.
1998: Matsushita M; Nairn A C
Characterization of the mechanism of regulation of Ca2+/ calmodulin-dependent protein kinase I by calmodulin and by Ca2+/calmodulin-dependent protein kinase kinase.
The Journal of biological chemistry 1998;273(34):21473-81.
1998: Greengard P; Nairn A C; Girault J A; Ouimet C C; Snyder G L; Fisone G; Allen P B; Fienberg A; Nishi A
The DARPP-32/protein phosphatase-1 cascade: a model for signal integration.
Brain research. Brain research reviews 1998;26(2-3):274-84.
1998: Allen P B; Kwon Y G; Nairn A C; Greengard P
Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit.
The Journal of biological chemistry 1998;273(7):4089-95.
1998: Desdouits F; Siciliano J C; Nairn A C; Greengard P; Girault J A
Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons.
The Biochemical journal 1998;330 ( Pt 1)():211-6.
1998: Desdouits-Magnen J; Desdouits F; Takeda S; Syu L J; Saltiel A R; Buxbaum J D; Czernik A J; Nairn A C; Greengard P
Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade.
Journal of neurochemistry 1998;70(2):524-30.
1997: Cheng X J; Höög J O; Nairn A C; Greengard P; Aperia A
Regulation of rat Na(+)-K(+)-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA.
The American journal of physiology 1997;273(6 Pt 1):C1981-6.
1997: Scheetz A J; Nairn A C; Constantine-Paton M
N-methyl-D-aspartate receptor activation and visual activity induce elongation factor-2 phosphorylation in amphibian tecta: a role for N-methyl-D-aspartate receptors in controlling protein synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14770-5.
1997: Gauss C M; Sheppeck J E; Nairn A C; Chamberlin R
A molecular modeling analysis of the binding interactions between the okadaic acid class of natural product inhibitors and the Ser-Thr phosphatases, PP1 and PP2A.
Bioorganic & medicinal chemistry 1997;5(9):1751-73.
1997: Belusa R; Wang Z M; Matsubara T; Sahlgren B; Dulubova I; Nairn A C; Ruoslahti E; Greengard P; Aperia A
Mutation of the protein kinase C phosphorylation site on rat alpha1 Na+,K+-ATPase alters regulation of intracellular Na+ and pH and influences cell shape and adhesiveness.
The Journal of biological chemistry 1997;272(32):20179-84.
1997: Marin P; Nastiuk K L; Daniel N; Girault J A; Czernik A J; Glowinski J; Nairn A C; Prémont J
Glutamate-dependent phosphorylation of elongation factor-2 and inhibition of protein synthesis in neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(10):3445-54.
1997: Suzuki T; Ando K; Isohara T; Oishi M; Lim G S; Satoh Y; Wasco W; Tanzi R E; Nairn A C; Greengard P; Gandy S E; Kirino Y
Phosphorylation of Alzheimer beta-amyloid precursor-like proteins.
Biochemistry 1997;36(15):4643-9.
1997: Kwon Y G; Huang H B; Desdouits F; Girault J A; Greengard P; Nairn A C
Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3536-41.
1997: Huang H B; Horiuchi A; Goldberg J; Greengard P; Nairn A C
Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor binding.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3530-5.
1997: Kwon Y G; Lee S Y; Choi Y; Greengard P; Nairn A C
Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2168-73.
1997: Oishi M; Nairn A C; Czernik A J; Lim G S; Isohara T; Gandy S E; Greengard P; Suzuki T
The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells.
Molecular medicine (Cambridge, Mass.) 1997;3(2):111-23.
1996: Marino M W; Dunbar J D; Wu L W; Ngaiza J R; Han H M; Guo D; Matsushita M; Nairn A C; Zhang Y; Kolesnick R; Jaffe E A; Donner D B
Inhibition of tumor necrosis factor signal transduction in endothelial cells by dimethylaminopurine.
The Journal of biological chemistry 1996;271(45):28624-9.
1996: Desdouits F; Buxbaum J D; Desdouits-Magnen J; Nairn A C; Greengard P
Amyloid alpha peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin, and calcineurin.
The Journal of biological chemistry 1996;271(40):24670-4.
1996: Logvinenko N S; Dulubova I; Fedosova N; Larsson S H; Nairn A C; Esmann M; Greengard P; Aperia A
Phosphorylation by protein kinase C of serine-23 of the alpha-1 subunit of rat Na+,K(+)-ATPase affects its conformational equilibrium.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9132-7.
1995: Goldberg J; Huang H B; Kwon Y G; Greengard P; Nairn A C; Kuriyan J
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
Nature 1995;376(6543):745-53.
1995: Picciotto M R; Zoli M; Bertuzzi G; Nairn A C
Immunochemical localization of calcium/calmodulin-dependent protein kinase I.
Synapse (New York, N.Y.) 1995;20(1):75-84.
1995: Desdouits F; Cohen D; Nairn A C; Greengard P; Girault J A
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase I in vitro and in vivo.
The Journal of biological chemistry 1995;270(15):8772-8.
1995: Desdouits F; Cheetham J J; Huang H B; Kwon Y G; da Cruz e Silva E F; Denefle P; Ehrlich M E; Nairn A C; Greengard P; Girault J A
Mechanism of inhibition of protein phosphatase 1 by DARPP-32: studies with recombinant DARPP-32 and synthetic peptides.
Biochemical and biophysical research communications 1995;206(2):652-8.
1995: Palfrey H C; Nairn A C
Calcium-dependent regulation of protein synthesis.
Advances in second messenger and phosphoprotein research 1995;30():191-223.
1994: Nairn A C; Picciotto M R
Calcium/calmodulin-dependent protein kinases.
Seminars in cancer biology 1994;5(4):295-303.
1994: Hwang T C; Nagel G; Nairn A C; Gadsby D C
Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4698-702.
1994: Suzuki T; Oishi M; Marshak D R; Czernik A J; Nairn A C; Greengard P
Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein.
The EMBO journal 1994;13(5):1114-22.
1994: Baukrowitz T; Hwang T C; Nairn A C; Gadsby D C
Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycle.
Neuron 1994;12(3):473-82.
1994: Fisone G; Cheng S X; Nairn A C; Czernik A J; Hemmings H C; Höög J O; Bertorello A M; Kaiser R; Bergman T; Jörnvall H
Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.
The Journal of biological chemistry 1994;269(12):9368-73.
1994: Gadsby D C; Hwang T C; Baukrowitz T; Nagel G; Horie M; Nairn A C
Regulation of CFTR channel gating.
The Japanese journal of physiology 1994;44 Suppl 2():S183-92.
1993: Gadsby D C; Hwang T C; Horie M; Nagel G; Nairn A C
Cardiac chloride channels: incremental regulation by phosphorylation/dephosphorylation.
Annals of the New York Academy of Sciences 1993;707():259-74.
1993: Picciotto M R; Czernik A J; Nairn A C
Calcium/calmodulin-dependent protein kinase I. cDNA cloning and identification of autophosphorylation site.
The Journal of biological chemistry 1993;268(35):26512-21.
1993: Gandy S E; Caporaso G L; Buxbaum J D; de Cruz Silva O; Iverfeldt K; Nordstedt C; Suzuki T; Czernik A J; Nairn A C; Greengard P
Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein.
Annals of the New York Academy of Sciences 1993;695():117-21.
1993: Mitsui K; Brady M; Palfrey H C; Nairn A C
Purification and characterization of calmodulin-dependent protein kinase III from rabbit reticulocytes and rat pancreas.
The Journal of biological chemistry 1993;268(18):13422-33.
1992: Gandy S E; Caporaso G L; Ramabhadran T V; Suzuki T; Buxbaum J D; Nordstedt C; Iverfeldt K; Czernik A J; Nairn A C; Greengard P
Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine.
Annals of the New York Academy of Sciences 1992;674():203-17.
1992: Nagel G; Hwang T C; Nastiuk K L; Nairn A C; Gadsby D C
The protein kinase A-regulated cardiac Cl- channel resembles the cystic fibrosis transmembrane conductance regulator.
Nature 1992;360(6399):81-4.
1992: Gandy S E; Buxbaum J D; Suzuki T; Ramabhadran T V; Caporaso G L; Nairn A C; Greengard P
The nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer beta/A4-amyloid precursor protein: some technical notes.
Neurobiology of aging 1992;13(5):601-3.
1992: Hemmings H C; Girault J A; Nairn A C; Bertuzzi G; Greengard P
Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.
Journal of neurochemistry 1992;59(3):1053-61.
1992: Picciotto M R; Cohn J A; Bertuzzi G; Greengard P; Nairn A C
Phosphorylation of the cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry 1992;267(18):12742-52.
1992: Hwang T C; Horie M; Nairn A C; Gadsby D C
Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance.
The Journal of general physiology 1992;99(4):465-89.
1991: Bertorello A M; Aperia A; Walaas S I; Nairn A C; Greengard P
Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11359-62.
1991: Greengard P; Jen J; Nairn A C; Stevens C F
Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons.
Science (New York, N.Y.) 1991;253(5024):1135-8.
1991: Gustafson E L; Girault J A; Hemmings H C; Nairn A C; Greengard P
Immunocytochemical localization of phosphatase inhibitor-1 in rat brain.
The Journal of comparative neurology 1991;310(2):170-88.
1991: Thelen M; Rosen A; Nairn A C; Aderem A
Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane.
Nature 1991;351(6324):320-2.
1991: Aperia A; Fryckstedt J; Svensson L; Hemmings H C; Nairn A C; Greengard P
Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2798-801.
1990: Hemmings H C; Nairn A C; Elliott J I; Greengard P
Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.
The Journal of biological chemistry 1990;265(33):20369-76.
1990: Thelen M; Rosen A; Nairn A C; Aderem A
Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5603-7.
1990: Horiuchi A; Williams K R; Kurihara T; Nairn A C; Greengard P
Purification and cDNA cloning of ARPP-16, a cAMP-regulated phosphoprotein enriched in basal ganglia, and of a related phosphoprotein, ARPP-19.
The Journal of biological chemistry 1990;265(16):9476-84.
1990: Brady M J; Nairn A C; Wagner J A; Palfrey H C
Nerve growth factor-induced down-regulation of calmodulin-dependent protein kinase III in PC12 cells involves cyclic AMP-dependent protein kinase.
Journal of neurochemistry 1990;54(3):1034-9.
1990: Nichols R A; Sihra T S; Czernik A J; Nairn A C; Greengard P
Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes.
Nature 1990;343(6259):647-51.
1990: Nairn A C
Role of Ca2+/calmodulin-dependent protein phosphorylation in signal transduction.
Advances in second messenger and phosphoprotein research 1990;24():202-5.
1989: Girault J A; Hemmings H C; Williams K R; Nairn A C; Greengard P
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.
The Journal of biological chemistry 1989;264(36):21748-59.
1989: Piomelli D; Wang J K; Sihra T S; Nairn A C; Czernik A J; Greengard P
Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8550-4.
1989: Meister B; Fryckstedt J; Schalling M; Cortés R; Hökfelt T; Aperia A; Hemmings H C; Nairn A C; Ehrlich M; Greengard P
Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):8068-72.
1989: Bahinski A; Nairn A C; Greengard P; Gadsby D C
Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes.
Nature 1989;340(6236):718-21.
1989: Rosen A; Nairn A C; Greengard P; Cohn Z A; Aderem A
Bacterial lipopolysaccharide regulates the phosphorylation of the 68K protein kinase C substrate in macrophages.
The Journal of biological chemistry 1989;264(16):9118-21.
1989: Mackie K; Sorkin B C; Nairn A C; Greengard P; Edelman G M; Cunningham B A
Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(6):1883-96.
1989: Hemmings H C; Nairn A C; McGuinness T L; Huganir R L; Greengard P
Role of protein phosphorylation in neuronal signal transduction.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(5):1583-92.
1989: Mackie K P; Nairn A C; Hampel G; Lam G; Jaffe E A
Thrombin and histamine stimulate the phosphorylation of elongation factor 2 in human umbilical vein endothelial cells.
The Journal of biological chemistry 1989;264(3):1748-53.
1989: Walaas S I; Nairn A C
Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanisms.
Journal of molecular neuroscience : MN 1989;1(2):117-27.
1988: Gorelick F S; Wang J K; Lai Y; Nairn A C; Greengard P
Autophosphorylation and activation of Ca2+/calmodulin-dependent protein kinase II in intact nerve terminals.
The Journal of biological chemistry 1988;263(33):17209-12.
1988: Thiel G; Czernik A J; Gorelick F; Nairn A C; Greengard P
Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6337-41.
1988: Nairn A C; Hemmings H C; Walaas S I; Greengard P
DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons.
Journal of neurochemistry 1988;50(1):257-62.
1988: Weeks G; Picciotto M; Nairn A C; Walaas S I; Greengard P
Purification and characterization of PCPP-260: a Purkinje cell-enriched cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.
Synapse (New York, N.Y.) 1988;2(1):89-96.
1987: Nairn A C; Palfrey H C
Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2.
The Journal of biological chemistry 1987;262(36):17299-303.
1987: Albert K A; Nairn A C; Greengard P
The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(20):7046-50.
1987: Nairn A C; Nichols R A; Brady M J; Palfrey H C
Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells.
The Journal of biological chemistry 1987;262(29):14265-72.
1987: Lai Y; Nairn A C; Gorelick F; Greengard P
Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5710-4.
1987: Thomas N E; Bramson H N; Nairn A C; Greengard P; Fry D C; Mildvan A S; Kaiser E T
Distinguishing among protein kinases by substrate specificities.
Biochemistry 1987;26(14):4471-4.

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