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Norimichi Nakahata

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Toshihiro Goto; Masaki Saito; Jun Sukegawa; Teruyuki Yanagisawa; Ayano Chiba; Norimichi Nakahata
Suppression of adenylyl cyclase-mediated cAMP production by plasma membrane associated cytoskeletal protein 4.1G.
Yutaro Obara; Yoshimi Yanagihata; Tomohiro Abe; Laila Dafik; Kuniaki Ishii; Norimichi Nakahata
Gα(h)/transglutaminase-2 activity is required for maximal activation of adenylylcyclase 8 in human and rat glioma cells.
Shinji Goto; Takahiro Moriya; Yutaro Obara; Masaki Saito; Norimichi Nakahata
Involvement of lipid rafts in multiple signal transductions mediated by two isoforms of thromboxane A₂ receptor: dependency on receptor isoforms and downstream signaling types.

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2013: Toshihiro Goto; Masaki Saito; Jun Sukegawa; Teruyuki Yanagisawa; Ayano Chiba; Norimichi Nakahata
Suppression of adenylyl cyclase-mediated cAMP production by plasma membrane associated cytoskeletal protein 4.1G.
Cellular signalling 2013;25(3):690-7.
2013: Yutaro Obara; Yoshimi Yanagihata; Tomohiro Abe; Laila Dafik; Kuniaki Ishii; Norimichi Nakahata
Gα(h)/transglutaminase-2 activity is required for maximal activation of adenylylcyclase 8 in human and rat glioma cells.
Cellular signalling 2013;25(3):589-97.
2012: Shinji Goto; Takahiro Moriya; Yutaro Obara; Masaki Saito; Norimichi Nakahata
Involvement of lipid rafts in multiple signal transductions mediated by two isoforms of thromboxane A₂ receptor: dependency on receptor isoforms and downstream signaling types.
European journal of pharmacology 2012;693(1-3):15-24.
2012: Satoshi Nishino; Yukio Numata; Koji Ohtomo; Tadahiro Sato; Norimichi Nakahata; Masatake Kurita
Divergent effects of lithium and sodium valproate on brain-derived neurotrophic factor (BDNF) production in human astrocytoma cells at therapeutic concentrations.
Progress in neuro-psychopharmacology & biological psychiatry 2012;39(1):17-22.
2012: Natsumi Mizuno; Noriyasu Hirasawa; Tokiko Suzuki; Norimichi Nakahata
Hetero-oligomerization between adenosine A₁ and thromboxane A₂ receptors and cellular signal transduction on stimulation with high and low concentrations of agonists for both receptors.
European journal of pharmacology 2012;677(1-3):5-14.
2012: Punnee Nusuetrong; Yoshiteru Oshima; Masaki Saito; Haruhisa Kikuchi; Takahiro Moriya; Norimichi Nakahata
Apoptotic effects of satratoxin H is mediated through DNA double-stranded break in PC12 cells.
The Journal of toxicological sciences 2012;37(4):803-12.
2011: Tokiko Suzuki; Takahiro Moriya; Hiroyasu Nakata; Yutaro Obara; Norimichi Nakahata
Functional interaction between purinergic receptors: effect of ligands for A2A and P2Y12 receptors on P2Y1 receptor function.
FEBS letters 2011;585(24):3978-84.
2011: Toshiki Chiba; Sanae Ueno; Yutaro Obara; Norimichi Nakahata
A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells.
The Journal of pharmacy and pharmacology 2011;63(5):636-47.
2011: Yutaro Obara; Wataru Nemoto; Susumu Kohno; Tomiyasu Murata; Norio Kaneda; Norimichi Nakahata
Basic fibroblast growth factor promotes glial cell-derived neurotrophic factor gene expression mediated by activation of ERK5 in rat C6 glioma cells.
Cellular signalling 2011;23(4):666-72.
2011: Koichiro Mori; Yutaro Obara; Takahiro Moriya; Satoshi Inatomi; Norimichi Nakahata
Effects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice.
Biomedical research (Tokyo, Japan) 2011;32(1):67-72.
2011: Yutaro Obara; Sanae Ueno; Yoshimi Yanagihata; Norimichi Nakahata
Lysophosphatidylinositol causes neurite retraction via GPR55, G13 and RhoA in PC12 cells.
PloS one 2011;6(8):e24284.
2011: Daisaku Kobayashi; Miho Kusama; Masaaki Onda; Norimichi Nakahata
The effect of pantothenic acid deficiency on keratinocyte proliferation and the synthesis of keratinocyte growth factor and collagen in fibroblasts.
Journal of pharmacological sciences 2011;115(2):230-4.
2010: Koichiro Mori; Haruhisa Kikuchi; Yutaro Obara; Masaya Iwashita; Yoshihito Azumi; Satomi Kinugasa; Satoshi Inatomi; Yoshiteru Oshima; Norimichi Nakahata
Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2010;17(14):1082-5.
2010: Koji Ando; Yutaro Obara; Jun Sugama; Atsushi Kotani; Nobuyuki Koike; Satoko Ohkubo; Norimichi Nakahata
P2Y2 receptor-Gq/11 signaling at lipid rafts is required for UTP-induced cell migration in NG 108-15 cells.
The Journal of pharmacology and experimental therapeutics 2010;334(3):809-19.
2010: Shizuko Akiyama; Hidenobu Ohta; Shimpei Watanabe; Takahiro Moriya; Aya Hariu; Norimichi Nakahata; Hiroshi Chisaka; Tadashi Matsuda; Yoshitaka Kimura; Shigeru Tsuchiya; Hajime Tei; Kunihiro Okamura; Nobuo Yaegashi
The uterus sustains stable biological clock during pregnancy.
The Tohoku journal of experimental medicine 2010;221(4):287-98.
2010: Masatake Kurita; Satoshi Nishino; Norimichi Nakahata
[Brain-derived neurotrophic factor (BDNF)].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 7():131-3.
2010: Takashi Katura; Takahiro Moriya; Norimichi Nakahata
15-Deoxy-delta 12,14-prostaglandin J2 biphasically regulates the proliferation of mouse hippocampal neural progenitor cells by modulating the redox state.
Molecular pharmacology 2010;77(4):601-11.
2010: Yutaro Obara; Norimichi Nakahata
The signaling pathway leading to extracellular signal-regulated kinase 5 (ERK5) activation via G-proteins and ERK5-dependent neurotrophic effects.
Molecular pharmacology 2010;77(1):10-6.
2010: Masaki Saito; Hiroyuki Tanaka; Masako Sasaki; Hitoshi Kurose; Norimichi Nakahata
Involvement of aquaporin in thromboxane A2 receptor-mediated, G 12/13/RhoA/NHE-sensitive cell swelling in 1321N1 human astrocytoma cells.
Cellular signalling 2010;22(1):41-6.
2009: Kotomi Uchiyama; Masaki Saito; Masako Sasaki; Yutaro Obara; Shigeki Higashiyama; Norimichi Nakahata
Thromboxane A2 receptor-mediated epidermal growth factor receptor transactivation: involvement of PKC-delta and PKC-epsilon in the shedding of epidermal growth factor receptor ligands.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;38(5):504-11.
2009: Shin-ichi Tokue; Masako Sasaki; Norimichi Nakahata
Thromboxane A2-induced signal transduction is negatively regulated by KIAA1005 that directly interacts with thromboxane A2 receptor.
Prostaglandins & other lipid mediators 2009;89(1-2):8-15.
2009: Yuiko Nasu; Masaya Iwashita; Masaki Saito; Shinji Fushiya; Norimichi Nakahata
Inhibitory effects of Atractylodis lanceae rhizoma and Poria on collagen- or thromboxane A2-induced aggregation in rabbit platelets.
Biological & pharmaceutical bulletin 2009;32(5):856-60.
2008: Koichiro Mori; Yutaro Obara; Mitsuru Hirota; Yoshihito Azumi; Satomi Kinugasa; Satoshi Inatomi; Norimichi Nakahata
Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells.
Biological & pharmaceutical bulletin 2008;31(9):1727-32.
2008: G N Bastos; T Moriya; F Inui; T Katura; Norimichi Nakahata
Involvement of cyclooxygenase-2 in lipopolysaccharide-induced impairment of the newborn cell survival in the adult mouse dentate gyrus.
Neuroscience 2008;155(2):454-62.
2008: Yutaro Obara; Yumiko Okano; Sachiko Ono; Arata Yamauchi; Tomohiro Hoshino; Hitoshi Kurose; Norimichi Nakahata
Betagamma subunits of G(i/o) suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced.
Cellular signalling 2008;20(7):1275-83.
2008: Punnee Nusuetrong; Thitima Pengsuparp; Duangdeun Meksuriyen; Masaaki Tanitsu; Haruhisa Kikuchi; Michinao Mizugaki; Ken-ichi Shimazu; Yoshiteru Oshima; Norimichi Nakahata; Makoto Yoshida
Satratoxin H generates reactive oxygen species and lipid peroxides in PC12 cells.
Biological & pharmaceutical bulletin 2008;31(6):1115-20.
2008: Norimichi Nakahata
Thromboxane A2: physiology/pathophysiology, cellular signal transduction and pharmacology.
Pharmacology & therapeutics 2008;118(1):18-35.
2007: Yutaro Obara; Asami Haganuma; Shinsuke Murakami; Toshiki Chiba; Koichiro Mori; Osamu Nakagawasai; Takeshi Tadano; Haruhisa Kikuchi; Yoshiteru Oshima; Norimichi Nakahata
5,19-cyclo-9beta,10xi-androstane-3,17-dione promotes neurotrophic factor biosynthesis in 1321N1 human astrocytoma cells and improves passive avoidance learning impairment.
Brain research 2007;1184():57-64.
2007: Daisaku Kobayashi; Satoko Ohkubo; Norimichi Nakahata
Cooperation of calcineurin and ERK for UTP-induced IL-6 production in HaCaT keratinocytes.
European journal of pharmacology 2007;573(1-3):249-52.
2007: Jun Sugama; jiangzhou yu; Mark M Rasenick; Norimichi Nakahata
Mastoparan inhibits beta-adrenoceptor-G(s) signaling by changing the localization of Galpha(s) in lipid rafts.
Cellular signalling 2007;19(11):2247-54.
2007: Masaya Iwashita; Nobuaki Oka; Satoko Ohkubo; Masaki Saito; Norimichi Nakahata
Piperlongumine, a constituent of Piper longum L., inhibits rabbit platelet aggregation as a thromboxane A(2) receptor antagonist.
European journal of pharmacology 2007;570(1-3):38-42.
2007: Masaya Iwashita; Masaki Saito; Yasunaga Yamaguchi; Ryoji Takagaki; Norimichi Nakahata
Inhibitory effect of ethanol extract of Piper longum L. on rabbit platelet aggregation through antagonizing thromboxane A2 receptor.
Biological & pharmaceutical bulletin 2007;30(7):1221-5.
2007: Masako Sasaki; Jun Sukegawa; Katsutoshi Miyosawa; Teruyuki Yanagisawa; Satoko Ohkubo; Norimichi Nakahata
Low expression of cell-surface thromboxane A2 receptor beta-isoform through the negative regulation of its membrane traffic by proteasomes.
Prostaglandins & other lipid mediators 2007;83(4):237-49.
2007: Norimichi Nakahata; Masaki Saito
[Regulation of G protein-coupled receptor function by its binding proteins].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2007;127(1):3-14.
2007: Norimichi Nakahata
[Novel functions and regulatory mechanisms of G protein-coupled receptors].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2007;127(1):1-2.
2007: Makoto Yoshida; Yukari Sato; Tokuro Shimura; Satoko Ohkubo; Shigeyoshi Honma; Takao Tanaka; Tadashi Kurimoto; Norimichi Nakahata
Distinct effects of z-335, a new thromboxane A2 receptor antagonist, on rabbit platelets and aortic smooth muscle.
Pharmacology 2007;79(1):50-6.
2006: Daisaku Kobayashi; Satoko Ohkubo; Norimichi Nakahata
Contribution of extracellular signal-regulated kinase to UTP-induced interleukin-6 biosynthesis in HaCaT keratinocytes.
Journal of pharmacological sciences 2006;102(4):368-76.
2006: Shigeyoshi Honma; Manami Saika; Satoko Ohkubo; Hitoshi Kurose; Norimichi Nakahata
Thromboxane A2 receptor-mediated G12/13-dependent glial morphological change.
European journal of pharmacology 2006;545(2-3):100-8.
2006: Masaki Saito; Megumi Hori; Yutaro Obara; Yasushi Ohizumi; Satoko Ohkubo; Norimichi Nakahata
Neurotrophic factor production in human astrocytoma cells by 2,5,6-tribromogramine via activation of epsilon isoform of protein kinase C.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;28(4):263-71.
2006: Yasufumi Toriniwa; Xiaochuan Lv; Yasuo Kodama; Yasushi Ohizumi; Makoto Yoshida; Norimichi Nakahata
Participation of epoxygenase activation in saikogenin D-induced inhibition of prostaglandin E(2) synthesis.
The Journal of pharmacy and pharmacology 2006;58(6):859-66.
2006: Katsutoshi Miyosawa; Masako Sasaki; Satoko Ohkubo; Norimichi Nakahata
Different pathways for activation of extracellular signal-regulated kinase through thromboxane A2 receptor isoforms.
Biological & pharmaceutical bulletin 2006;29(4):719-24.
2006: Masako Sasaki; Katsutoshi Miyosawa; Satoko Ohkubo; Norimichi Nakahata
Physiological significance of thromboxane A(2) receptor dimerization.
Journal of pharmacological sciences 2006;100(4):263-70.
2005: Masaki Saito; Maki Sugai; Yuriko Katsushima; Teruyuki Yanagisawa; Jun Sukegawa; Norimichi Nakahata
Increase in cell-surface localization of parathyroid hormone receptor by cytoskeletal protein 4.1G.
The Biochemical journal 2005;392(Pt 1):75-81.
2005: Jun Sugama; Satoko Ohkubo; Masanori Atsumi; Norimichi Nakahata
Mastoparan changes the cellular localization of Galphaq/11 and Gbeta through its binding to ganglioside in lipid rafts.
Molecular pharmacology 2005;68(5):1466-74.
2005: Haruhisa Kikuchi; Yoshinori Saito; Jun'ichi Sekiya; Yumiko Okano; Masaki Saito; Norimichi Nakahata; Yuzuru Kubohara; Yoshiteru Oshima
Isolation and synthesis of a new aromatic compound, brefelamide, from dictyostelium cellular slime molds and its inhibitory effect on the proliferation of astrocytoma cells.
The Journal of organic chemistry 2005;70(22):8854-8.
2005: Yutaro Obara; Hitoshi Kurose; Norimichi Nakahata
Thromboxane A2 promotes interleukin-6 biosynthesis mediated by an activation of cyclic AMP-response element-binding protein in 1321N1 human astrocytoma cells.
Molecular pharmacology 2005;68(3):670-9.
2005: Punnee Nusuetrong; Makoto Yoshida; Masa-aki Tanitsu; Haruhisa Kikuchi; Michinao Mizugaki; Ken-ichi Shimazu; Thitima Pengsuparp; Duangdeun Meksuriyen; Yoshiteru Oshima; Norimichi Nakahata
Involvement of reactive oxygen species and stress-activated MAPKs in satratoxin H-induced apoptosis.
European journal of pharmacology 2005;507(1-3):239-46.
2004: Shin-ya Saito; Sachie Kamiyama; Mayumi Oda; Norimichi Nakahata; Yasushi Ohizumi
Inhibitory effect of Mao-Bushi-Saishin-to on prostaglandin E2 synthesis in C6 rat glioma cells.
Biological & pharmaceutical bulletin 2004;27(7):1133-5.
2004: Shin-ya Saito; Yukiko Maruyama; Sachie Kamiyama; Norimichi Nakahata; Yasushi Ohizumi
Ephedrae herba in Mao-Bushi-Saishin-To inhibits IgE-mediated histamine release and increases cAMP content in RBL-2H3 cells.
Journal of pharmacological sciences 2004;95(1):41-6.
2004: Haruhisa Kikuchi; Yasuhiro Miyagawa; Yuko Sahashi; Satoshi Inatomi; Asami Haganuma; Norimichi Nakahata; Yoshiteru Oshima
Novel spirocyclic trichothecanes, spirotenuipesine A and B, isolated from entomopathogenic fungus, Paecilomyces tenuipes.
The Journal of organic chemistry 2004;69(2):352-6.
2003: Maki Sugai; Masaki Saito; Izumi Sukegawa; Yuriko Katsushima; Yoshitaka Kinouchi; Norimichi Nakahata; Tooru Shimosegawa; Teruyuki Yanagisawa; Jun Sukegawa
PTH/PTH-related protein receptor interacts directly with Tctex-1 through its COOH terminus.
Biochemical and biophysical research communications 2003;311(1):24-31.
2003: Norimichi Nakahata; Satoko Ohkubo
[Lipid rafts and their analytical methods].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2003;122(5):419-25.
2003: Yasuo Kodama; Lv Xiaochuan; Chikako Tsuchiya; Yasushi Ohizumi; Makoto Yoshida; Norimichi Nakahata
Dual effect of saikogenin D: in vitro inhibition of prostaglandin E2 production and elevation of intracellular free Ca2+ concentration in C6 rat glioma cells.
Planta medica 2003;69(8):765-7.
2003: Yutaka Hirata; Masanori Atsumi; Yasushi Ohizumi; Norimichi Nakahata
Mastoparan binds to glycogen phosphorylase to regulate sarcoplasmic reticular Ca2+ release in skeletal muscle.
The Biochemical journal 2003;371(Pt 1):81-8.
2003: Norimichi Nakahata; Chikako Tsuchiya; Keigo Nakatani; Yasushi Ohizumi; Satoko Ohkubo
Baicalein inhibits Raf-1-mediated phosphorylation of MEK-1 in C6 rat glioma cells.
European journal of pharmacology 2003;461(1):1-7.
2002: Minori MiTSUI-SAITO; Satoko Ohkubo; Yutaro Obara; Teruyuki Yanagisawa; Jun'Ichi Kobayashi; Yasushi Ohizumi; Norimichi Nakahata
Theonezolide A, a novel marine macrolide, induces drastic shape change in rabbit platelets by reorganization of microtubules.
Thrombosis research 2002;108(2-3):133-8.
2002: Keigo Nakatani; Masanori Atsumi; Tsutomu Arakawa; Kenji Oosawa; Susumu Shimura; Norimichi Nakahata; Yasushi Ohizumi
Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant.
Biological & pharmaceutical bulletin 2002;25(9):1137-41.
2002: Keigo Nakatani; Norimichi Nakahata; Tsutomu Arakawa; Hideyuki Yasuda; Yasushi Ohizumi
Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells.
Biochemical pharmacology 2002;63(1):73-9.
2001: Keigo Nakatani; Norimichi Nakahata; S Tsurufuji; Yasushi Ohizumi
Preconditioning of 3T3 cells by fresh medium together with genistein enhances prostaglandin E(2) release.
European journal of pharmacology 2001;432(2-3):135-42.
2001: Haruhisa Kikuchi; Y Saito; J Komiya; Yoshiaki Takaya; S Honma; Norimichi Nakahata; A Ito; Yoshiteru Oshima
Furanodictine A and B: amino sugar analogues produced by cellular slime mold Dictyostelium discoideum showing neuronal differentiation activity.
The Journal of organic chemistry 2001;66(21):6982-7.
2001: Yutaro Obara; H Kobayashi; T Ohta; Yasushi Ohizumi; Norimichi Nakahata
Scabronine G-methylester enhances secretion of neurotrophic factors mediated by an activation of protein kinase C-zeta.
Molecular pharmacology 2001;59(5):1287-97.
2000: Yutaro Obara; Norimichi Nakahata; Y Mizushina; F Sugawara; K Sakaguchi; Yasushi Ohizumi
Differentiation of rat pheochromocytoma cells by fomitellic acids, specific DNA polymerase inhibitors.
Life sciences 2000;67(13):1659-65.
2000: Yutaka Hirata; Norimichi Nakahata; Yasushi Ohizumi
Identification of a 97-kDa mastoparan-binding protein involving in Ca(2+) release from skeletal muscle sarcoplasmic reticulum.
Molecular pharmacology 2000;57(6):1235-42.
2000: H Kobayashi; S Honma; Norimichi Nakahata; Yasushi Ohizumi
Involvement of phosphatidylcholine-specific phospholipase C in thromboxane A2-induced activation of mitogen-activated protein kinase in astrocytoma cells.
Journal of neurochemistry 2000;74(5):2167-73.
2000: Minori MiTSUI-SAITO; Norimichi Nakahata; Yasushi Ohizumi
Inhibition of microtubule polymerization by SK&F 96365, a blocker of receptor-linked Ca2+ entry.
Japanese journal of pharmacology 2000;82(3):269-71.
2000: Norimichi Nakahata; H Takano; Yasushi Ohizumi
Thromboxane A2 receptor-mediated tonic contraction is attributed to an activation of phosphatidylcholine-specific phospholipase C in rabbit aortic smooth muscles.
Life sciences 2000;66(5):PL 71-6.
1999: R Kyo; Norimichi Nakahata; Y Kodama; Y Nakai; M Kubo; Yasushi Ohizumi
Antagonism of saikosaponin-induced prostaglandin E2 release by baicalein in C6 rat glioma cells.
Biological & pharmaceutical bulletin 1999;22(12):1385-7.
1999: Norimichi Nakahata; Y Harada; M Tsuji; K Kon-ya; Y Shizuri; Yasushi Ohizumi
Structure-activity relationship of gramine derivatives in Ca(2+) release from sarcoplasmic reticulum.
European journal of pharmacology 1999;382(2):129-32.
1999: Kimihiro Matsunaga; K Nakatani; M Murakami; Norimichi Nakahata; Yasushi Ohizumi
[Goniodomin A induces modulation of actomyosin ATPase activity mediated through conformational change of actin].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1999;114 Suppl 1():220P-224P.
1999: Norimichi Nakahata; R Kyo; M Kutsuwa; Yasushi Ohizumi
[Inhibition of mitogen-activated protein kinase cascade by baicalein, a flavonoid of natural origin].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1999;114 Suppl 1():215P-219P.
1999: Norimichi Nakahata; T Yaginuma; Yasushi Ohizumi
Maitotoxin-induced phosphoinositide hydrolysis is dependent on extracellular but not intracellular Ca2+ in human astrocytoma cells.
Japanese journal of pharmacology 1999;81(2):240-3.
1999: Norimichi Nakahata; S Ohkubo; E Ito; M Nakano; K Terao; Yasushi Ohizumi
Comparison of maitotoxin with thromboxane A2 in rabbit platelet activation.
Toxicon : official journal of the International Society on Toxinology 1999;37(10):1375-89.
1999: S Honma; Norimichi Nakahata; H Kobayashi; S Ikeda; N Takeda; Yasushi Ohizumi
Decrease in thromboxane A2 receptor expression by differentiation with dibutyryl cyclic AMP in 1321N1 human astrocytoma cells.
Prostaglandins & other lipid mediators 1999;58(1):51-62.
1999: Yutaro Obara; M Takahashi; Norimichi Nakahata; Yasushi Ohizumi
Maitotoxin-induced nerve growth factor production accompanied by the activation of a voltage-insensitive Ca2+ channel in C6-BU-1 glioma cells.
British journal of pharmacology 1999;127(7):1577-82.
1999: Norimichi Nakahata; H Takano; Yasushi Ohizumi
Thromboxane A2-induced phosphatidylcholine hydrolysis in porcine vascular smooth muscle cells.
European journal of pharmacology 1999;374(1):157-60.
1999: Yutaro Obara; Norimichi Nakahata; T Kita; Yoshiaki Takaya; H Kobayashi; Shinzo Hosoi; Fumiyuki Kiuchi; T Ohta; Yoshiteru Oshima; Yasushi Ohizumi
Stimulation of neurotrophic factor secretion from 1321N1 human astrocytoma cells by novel diterpenoids, scabronines A and G.
European journal of pharmacology 1999;370(1):79-84.
1998: Norimichi Nakahata; S Honma; H Kobayashi; Yasushi Ohizumi
[Thromboxane A2 receptor-mediated signal transduction in glial cells].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1998;112 Suppl 1():113P-117P.
1998: K Tsukii; Norimichi Nakahata; S Tsurufuji; Yasushi Ohizumi
Ca2+-independent synergistic augmentation of O2- production by FMLP and PMA in HL-60 cells.
Canadian journal of physiology and pharmacology 1998;76(10-11):1024-32.
1998: R Kyo; Norimichi Nakahata; I Sakakibara; M Kubo; Yasushi Ohizumi
Effects of Sho-saiko-to, San'o-shashin-to and Scutellariae Radix on intracellular Ca2+ mobilization in C6 rat glioma cells.
Biological & pharmaceutical bulletin 1998;21(10):1067-71.
1998: R Kyo; Norimichi Nakahata; I Sakakibara; M Kubo; Yasushi Ohizumi
Baicalin and baicalein, constituents of an important medicinal plant, inhibit intracellular Ca2+ elevation by reducing phospholipase C activity in C6 rat glioma cells.
The Journal of pharmacy and pharmacology 1998;50(10):1179-82.
1998: Keigo Nakatani; Norimichi Nakahata; Y Hamada; S Tsurufuji; Yasushi Ohizumi
Medium change amplifies mitogen-activated protein kinase-mediated prostaglandin E2 synthesis in Swiss 3T3 fibroblasts.
European journal of pharmacology 1998;356(1):91-100.
1998: M Kutsuwa; Norimichi Nakahata; K Hayashi; M Kubo; Yasushi Ohizumi
A comparative study of Kakkon-to and Keishi-to on prostaglandin E(2) release from rabbit astrocytes.
Phytomedicine : international journal of phytotherapy and phytopharmacology 1998;5(4):275-82.
1998: K Mizuno; Norimichi Nakahata; E Ito; M Murakami; K Yamaguchi; Yasushi Ohizumi
Goniodomin A, an antifungal polyether macrolide, increases the filamentous actin content of 1321N1 human astrocytoma cells.
The Journal of pharmacy and pharmacology 1998;50(6):645-8.
1998: K Mizuno; Norimichi Nakahata; Yasushi Ohizumi
Characterization of mastoparan-induced histamine release from RBL-2H3 cells.
Toxicon : official journal of the International Society on Toxinology 1998;36(3):447-56.
1998: Norimichi Nakahata; M Kutsuwa; R Kyo; M Kubo; K Hayashi; Yasushi Ohizumi
Analysis of inhibitory effects of scutellariae radix and baicalein on prostaglandin E2 production in rat C6 glioma cells.
The American journal of Chinese medicine 1998;26(3-4):311-23.
1998: MC Rho; Norimichi Nakahata; Yasushi Ohizumi
Two distinct effects of 12S-hydroxyeicosatetraenoic acid on platelet aggregation by zooxanthellatoxin-A and ionomycin.
Japanese journal of pharmacology 1998;76(1):117-20.
1997: Norimichi Nakahata; MC Rho; Yasushi Ohizumi
[Effect of zooxanthellatoxin-A, an unique marine product, on arachidonic acid cascade in rabbit platelets].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1997;110 Suppl 1():189P-194P.
1997: MC Rho; Norimichi Nakahata; H Nakamura; A Murai; Yasushi Ohizumi
Involvement of phospholipase C-gamma2 in activation of mitogen-activated protein kinase and phospholipase A2 by zooxanthellatoxin-A in rabbit platelets.
The Journal of pharmacology and experimental therapeutics 1997;282(1):496-504.
1997: MC Rho; Norimichi Nakahata; H Nakamura; A Murai; Yasushi Ohizumi
Tyrphostin 23 blocks phosphorylation of p42 but not p38 mitogen-activated protein kinase by zooxanthellatoxin-A.
European journal of pharmacology 1997;319(2-3):375-8.