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Keisuke Nakajou

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Koji Nishi; Ayaka Suenaga; Nao Uehara; Hiroshi Watanabe; Naoko Fukunaga; Mari Kikuchi; Hisakazu Komori; Toru Maruyama; Kazuaki Matsumoto; Shogo Misumi; Keisuke Nakajou; Masaki Otagiri
Characterization of the hepatic cellular uptake of α(1) -acid glycoprotein (AGP), part 1: a peptide moiety of human AGP is recognized by the hemoglobin β-chain on mouse liver parenchymal cells.
Yu Ishima; Toshiya Kai; Naohisa Katayama; Ulrich Kragh-Hansen; Toru Maruyama; Keisuke Nakajou; Kaori Watanabe; Fumika Yoshida; Takaaki Akaike; Masaki Otagiri
Cellular uptake mechanisms and responses to NO transferred from mono- and poly-S-nitrosated human serum albumin.
Shotaro Ikuta; Victor Chuang; Yu Ishima; Keisuke Nakajou; Masato Furukawa; Hiroshi Watanabe; Toru Maruyama; Masaki Otagiri
Albumin fusion of thioredoxin--the production and evaluation of its biological activity for potential therapeutic applications.

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All Publications

2012: Koji Nishi; Ayaka Suenaga; Nao Uehara; Hiroshi Watanabe; Naoko Fukunaga; Mari Kikuchi; Hisakazu Komori; Toru Maruyama; Kazuaki Matsumoto; Shogo Misumi; Keisuke Nakajou; Masaki Otagiri
Characterization of the hepatic cellular uptake of α(1) -acid glycoprotein (AGP), part 1: a peptide moiety of human AGP is recognized by the hemoglobin β-chain on mouse liver parenchymal cells.
Journal of pharmaceutical sciences 2012;101(4):1599-606.
2011: Yu Ishima; Toshiya Kai; Naohisa Katayama; Ulrich Kragh-Hansen; Toru Maruyama; Keisuke Nakajou; Kaori Watanabe; Fumika Yoshida; Takaaki Akaike; Masaki Otagiri
Cellular uptake mechanisms and responses to NO transferred from mono- and poly-S-nitrosated human serum albumin.
Free radical research 2011;45(10):1196-206.
2010: Shotaro Ikuta; Victor Chuang; Yu Ishima; Keisuke Nakajou; Masato Furukawa; Hiroshi Watanabe; Toru Maruyama; Masaki Otagiri
Albumin fusion of thioredoxin--the production and evaluation of its biological activity for potential therapeutic applications.
Journal of controlled release : official journal of the Controlled Release Society 2010;147(1):17-23.
2010: Kenshiro Hirata; Toru Maruyama; Hiroshi Watanabe; Hitoshi Maeda; Keisuke Nakajou; Yasunori Iwao; Yu Ishima; Hidemasa Katsumi; Mitsuru Hashida; Masaki Otagiri
Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics.
Journal of controlled release : official journal of the Controlled Release Society 2010;145(1):9-16.
2010: Naohisa Katayama; Keisuke Nakajou; Yu Ishima; Shotaro Ikuta; Jun-ichi Yokoe; Fumika Yoshida; Ayaka Suenaga; Toru Maruyama; Toshiya Kai; Masaki Otagiri
Nitrosylated human serum albumin (SNO-HSA) induces apoptosis in tumor cells.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2010;22(4):259-65.
2010: Kazuaki Matsumoto; Koji Nishi; Mari Kikuchi; Hiroshi Watanabe; Keisuke Nakajou; Hisakazu Komori; Daisuke Kadowaki; Ayaka Suenaga; Toru Maruyama; Masaki Otagiri
Receptor-mediated uptake of human alpha1-acid glycoprotein into liver parenchymal cells in mice.
Drug metabolism and pharmacokinetics 2010;25(1):101-7.
2008: Yasunori Iwao; Keisuke Nakajou; Ryoji Nagai; Kenichiro Kitamura; Makoto Anraku; Toru Maruyama; Masaki Otagiri
CD36 is one of important receptors promoting renal tubular injury by advanced oxidation protein products.
American journal of physiology. Renal physiology 2008;295(6):F1871-80.
2008: Naohisa Katayama; Keisuke Nakajou; Hisakazu Komori; Kunitoshi Uchida; Jun-Ichi Yokoe; Norikiyo Yasui; Hisashi Yamamoto; Toshiya Kai; Makoto Sato; Takenobu Nakagawa; Motohiro Takeya; Toru Maruyama; Masaki Otagiri
Design and evaluation of S-nitrosylated human serum albumin as a novel anticancer drug.
The Journal of pharmacology and experimental therapeutics 2008;325(1):69-76.
2007: Ryoji Nagai; Katsumi Mera; Keisuke Nakajou; Yukio Fujiwara; Yasunori Iwao; Hiroki Imai; Toshinori Murata; Masaki Otagiri
The ligand activity of AGE-proteins to scavenger receptors is dependent on their rate of modification by AGEs.
Biochimica et biophysica acta 2007;1772(11-12):1192-8.
2006: Ulrich Kragh-Hansen; Hiroshi Watanabe; Keisuke Nakajou; Yasunori Iwao; Masaki Otagiri
Chain length-dependent binding of fatty acid anions to human serum albumin studied by site-directed mutagenesis.
Journal of molecular biology 2006;363(3):702-12.
2006: Nahoko Nakano; Kaori Fukuhara-Takaki; Tadashi Jono; Keisuke Nakajou; Nobuaki ETO; Seikoh Horiuchi; Motohiro Takeya; Ryoji Nagai
Association of advanced glycation end products with A549 cells, a human pulmonary epithelial cell line, is mediated by a receptor distinct from the scavenger receptor family and RAGE.
Journal of biochemistry 2006;139(5):821-9.
2006: Yasunori Iwao; Makoto Anraku; Mikako Hiraike; Keiichi Kawai; Keisuke Nakajou; Toshiya Kai; Ayaka Suenaga; Masaki Otagiri
The structural and pharmacokinetic properties of oxidized human serum albumin, advanced oxidation protein products (AOPP).
Drug metabolism and pharmacokinetics 2006;21(2):140-6.
2005: Katsumi Mera; Makoto Anraku; Kenichiro Kitamura; Keisuke Nakajou; Toru Maruyama; Kimio Tomita; Masaki Otagiri
Oxidation and carboxy methyl lysine-modification of albumin: possible involvement in the progression of oxidative stress in hemodialysis patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2005;28(12):973-80.
2005: Katsumi Mera; Makoto Anraku; Kenichiro Kitamura; Keisuke Nakajou; Toru Maruyama; Masaki Otagiri
The structure and function of oxidized albumin in hemodialysis patients: Its role in elevated oxidative stress via neutrophil burst.
Biochemical and biophysical research communications 2005;334(4):1322-8.
2005: Keisuke Nakajou; Seikoh Horiuchi; Masakazu Sakai; Kenshiro Hirata; Makiko Tanaka; Motohiro Takeya; Toshiya Kai; Masaki Otagiri
CD36 is not involved in scavenger receptor-mediated endocytic uptake of glycolaldehyde- and methylglyoxal-modified proteins by liver endothelial cells.
Journal of biochemistry 2005;137(5):607-16.
2005: Keisuke Nakajou; Seikoh Horiuchi; Masakazu Sakai; Nozomu Haraguchi; M Tanaka; Motohiro Takeya; Masaki Otagiri
Renal clearance of glycolaldehyde- and methylglyoxal-modified proteins in mice is mediated by mesangial cells through a class A scavenger receptor (SR-A).
Diabetologia 2005;48(2):317-27.
2003: Keisuke Nakajou; Hiroshi Watanabe; Ulrich Kragh-Hansen; Toru Maruyama; Masaki Otagiri
The effect of glycation on the structure, function and biological fate of human serum albumin as revealed by recombinant mutants.
Biochimica et biophysica acta 2003;1623(2-3):88-97.
2001: Hiroshi Watanabe; Ulrich Kragh-Hansen; Sumio Tanase; Keisuke Nakajou; M Mitarai; Yasunori Iwao; Toru Maruyama; Masaki Otagiri
Conformational stability and warfarin-binding properties of human serum albumin studied by recombinant mutants.
The Biochemical journal 2001;357(Pt 1):269-74.
2000: Hiroshi Watanabe; Sumio Tanase; Keisuke Nakajou; Toru Maruyama; Ulrich Kragh-Hansen; Masaki Otagiri
Role of arg-410 and tyr-411 in human serum albumin for ligand binding and esterase-like activity.
The Biochemical journal 2000;349 Pt 3():813-9.