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Junzo Nakamura
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64
Nishida, Koyo
61
Sasaki, Hitoshi
35
Nakashima, Mikiro
23
Mukai, Takahiro
13
Fumoto, Shintaro
12
Sakaeda, Toshiyuki
11
Kawakami, Shigeru
10
Nishi, Junya
9
Hirayama, Ryu
7
Kodama, Yukinobu
4
Kuma, Akiko
4
Fumoto, Shintaro
3
Arano, Yasushi
3
Horimoto, Tomomi
3
Saji, Hideo
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All Publications
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2009: Kurosaki Tomoaki; Kitahara Takashi; Kawakami Shigeru; Nishida Koyo; Nakamura Junzo; Teshima Mugen; Nakagawa Hiroo; Kodama Yukinobu; To Hideto; Sasaki Hitoshi
The development of a gene vector electrostatically assembled with a polysaccharide capsule.
Biomaterials 2009;30(26):4427-34.
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2009: Fumoto Shintaro; Tsuchimochi Mayumi; Nishi Junya; Ishii Hiroki; Kodama Yukinobu; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo; Nishida Koyo
Liver- and lobe-specific gene transfer following the continuous microinstillation of Plasmid DNA onto the liver surface in mice: effect of instillation speed.
Biological & pharmaceutical bulletin 2009;32(7):1298-302.
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2009: Fumoto Shintaro; Nishi Junya; Ishii Hiroki; Wang Xuan; Miyamoto Hirotaka; Yoshikawa Naoki; Nakashima Mikiro; Nakamura Junzo; Nishida Koyo
Rac-mediated macropinocytosis is a critical route for naked plasmid DNA transfer in mice.
Molecular pharmaceutics 2009;6(4):1170-9.
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2008: Fumoto Shintaro; Nishi Junya; Nakamura Junzo; Nishida Koyo
Gene therapy for gastric diseases.
Current gene therapy 2008;8(3):187-200.
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2008: Nishi Junya; Fumoto Shintaro; Ishii Hiroki; Kodama Yukinobu; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo; Nishida Koyo
Improved stomach selectivity of gene expression following microinstillation of plasmid DNA onto the gastric serosal surface in mice.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;69(2):633-9.
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2008: Kodama Yukinobu; Fumoto Shintaro; Nishi Junya; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo; Nishida Koyo
Absorption and distribution characteristics of 5-fluorouracil (5-FU) after an application to the liver surface in rats in order to reduce systemic side effects.
Biological & pharmaceutical bulletin 2008;31(5):1049-52.
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2008: Nakashima Mikiro; Nakamura Tadahiro; Teshima Mugen; To Hideto; Uematsu Masafumi; Kitaoka Takashi; Taniyama Kotaro; Nishida Koyo; Nakamura Junzo; Sasaki Hitoshi
Breakdown evaluation of corneal epithelial barrier caused by antiallergic eyedrops using an electrophysiologic method.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2008;24(1):43-51.
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2007: Fumoto Shintaro; Nakashima Yukiko; Nishida Koyo; Kodama Yukinobu; Nishi Junya; Nakashima Mikiro; Sasaki Hitoshi; Otsuka Noboru; Nakamura Junzo
Evaluation of enhanced peritoneum permeability in methylglyoxal-treated rats as a diagnostic method for peritoneal damage.
Pharmaceutical research 2007;24(10):1891-6.
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2007: Nishida Koyo; Okazaki Madoka; Sakamoto Ryuichi; Inaoka Natsuko; Miyake Hideaki; Fumoto Shintaro; Nakamura Junzo; Nakashima Mikiro; Sasaki Hitoshi; Kakumoto Mikio; Sakaeda Toshiyuki
Change in pharmacokinetics of model compounds with different elimination processes in rats during hypothermia.
Biological & pharmaceutical bulletin 2007;30(9):1763-7.
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2007: Nakamura Junzo; Fumoto Shintaro; Kawanami Rie; Kodama Yukinobu; Nishi Junya; Nakashima Mikiro; Sasaki Hitoshi; Nishida Koyo
Spleen-selective gene transfer following the administration of naked plasmid DNA onto the spleen surface in mice.
Biological & pharmaceutical bulletin 2007;30(5):941-5.
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2007: Nakamura Junzo; Fumoto Shintaro; Ariyoshi Kimiyo; Kodama Yukinobu; Nishi Junya; Nakashima Mikiro; Sasaki Hitoshi; Nishida Koyo
Unilateral lung-selective gene transfer following the administration of naked plasmid DNA onto the pulmonary pleural surface in mice.
Biological & pharmaceutical bulletin 2007;30(4):729-32.
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2006: Nakamura Junzo; Fumoto Shintaro; Shoji Keiko; Kodama Yukinobu; Nishi Junya; Nakashima Mikiro; Sasaki Hitoshi; Nishida Koyo
Stomach-selective gene transfer following the administration of naked plasmid DNA onto the gastric serosal surface in mice.
Biological & pharmaceutical bulletin 2006;29(10):2082-6.
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2005: Hirayama Ryu; Fumoto Shintaro; Nishida Koyo; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo
Effect of solution composition of plasmid DNA on gene transfection following liver surface administration in mice.
Biological & pharmaceutical bulletin 2005;28(11):2166-9.
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2005: Nishida Koyo; Kuma Akiko; Fumoto Shintaro; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo
Absorption characteristics of model compounds from the small intestinal serosal surface and a comparison with other organ surfaces.
The Journal of pharmacy and pharmacology 2005;57(8):1073-7.
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2005: Nishida Koyo; Fujiwara Rie; Kodama Yukinobu; Fumoto Shintaro; Mukai Takahiro; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo
Regional delivery of model compounds and 5-Fluorouracil to the liver by their application to the liver surface in rats: its implication for clinical use.
Pharmaceutical research 2005;22(8):1331-7.
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2005: Nakamura Junzo; Kobayashi Kazuko; Fumoto Shintaro; Nishi Junya; Mukai Takahiro; Nakashima Mikiro; Sasaki Hitoshi; Nishida Koyo
Stomach- and site-selective delivery of 5-fluorouracil following its application on the gastric serosal surface in rats.
Biological & pharmaceutical bulletin 2005;28(6):1049-53.
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2005: Nishida Koyo; Kamenosono Manabu; Kuma Akiko; Fumoto Shintaro; Mukai Takahiro; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo
Delivery advantage to the unilateral kidney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model.
Journal of drug targeting 2005;13(4):215-23.
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2005: Hirayama Ryu; Nishida Koyo; Fumoto Shintaro; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo
Unilateral kidney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice.
Biological & pharmaceutical bulletin 2005;28(1):181-4.
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2004: Nishida Koyo; Tomiyama Naoki; Mukai Takahiro; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo
Absorption characteristics of compounds with different molecular weights after application to the unilateral kidney surface in rats.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(3):705-11.
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2004: Hirayama Ryu; Nishida Koyo; Fumoto Shintaro; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo
Liver site-specific gene transfer following the administration of naked plasmid DNA to the liver surface in mice.
Biological & pharmaceutical bulletin 2004;27(10):1697-9.
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2004: Kawakami Shigeru; Harada Ayaka; Sakanaka Koji; Nishida Koyo; Nakamura Junzo; Sakaeda Toshiyuki; Ichikawa Nobuhiro; Nakashima Mikiro; Sasaki Hitoshi
In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits.
International journal of pharmaceutics 2004;278(2):255-62.
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2004: Nishida Koyo; Nose Seiichi; Kuma Akiko; Mukai Takahiro; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo
Absorption of phenolsulfonphthalein as a model across the mesenteric surface in rats to determine the drug absorption route after intraperitoneal administration.
The Journal of pharmacy and pharmacology 2004;56(5):683-7.
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2004: Mukai Takahiro; Mera Kunihiro; Nishida Koyo; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo
Pharmacokinetics of phenol red in rat models of liver damage prepared by liver targeting of carbon tetrachloride.
Biological & pharmaceutical bulletin 2004;27(4):595-7.
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2003: Nakamura Junzo; Horimoto Tomomi; Hirayama Ryu; Mukai Takahiro; Nakashima Mikiro; Sasaki Hitoshi; Nishida Koyo
Further studies on the kidney- and site-selective delivery of 5-fluorouracil following kidney surface application in rats.
Biological & pharmaceutical bulletin 2003;26(12):1761-4.
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2003: Nakamura Junzo; Horimoto Tomomi; Hirayama Ryu; Mukai Takahiro; Nakashima Mikiro; Sasaki Hitoshi; Nishida Koyo
Effect of the absorption enhancer saponin on the intrarenal distribution of 5-fluorouracil following its kidney surface application in rats.
Biological & pharmaceutical bulletin 2003;26(7):1049-51.
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2003: Nishida Koyo; Honda Tominori; Nakashima Mikiro; Sasaki Hitoshi; Nakamura Junzo
Influence of liver disease on phenolsulfonphthalein absorption from liver surface to examine possibility of direct liver surface application for drug targeting.
Biological & pharmaceutical bulletin 2003;26(7):988-93.
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2003: Hirayama Ryu; Kawakami Shigeru; Nishida Koyo; Nakashima Mikiro; Sasaki Hitoshi; Sakeda Toshiyuki; Nakamura Junzo
Development of the liver- and lobe-selective nonviral gene transfer following the instillation of naked plasmid DNA using catheter on the liver surface in mice.
Pharmaceutical research 2003;20(2):328-32.
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2002: Mukai Takahiro; Mera Kunihiro; Nishida Koyo; Nakashima Mikiro; Sasaki Hitoshi; Sakaeda Toshiyuki; Nakamura Junzo
A novel method for preparation of animal models of liver damage: liver targeting of carbon tetrachloride in rats.
Biological & pharmaceutical bulletin 2002;25(11):1494-7.
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2002: Kawakami Shigeru; Ohshima Nao; Hirayama Ryu; Al Masami Hi; Kitahara Takashi; Sakaeda Toshiyuki; Mukai Takahiro; Nishida Koyo; Nakamura Junzo; Nakashima Mikiro; Sasaki Hitoshi
Biodistribution and pharmacokinetics of O-palmitoyl tilisolol, a lipophilic prodrug of tilisolol, after intravenous administration in rats.
Biological & pharmaceutical bulletin 2002;25(8):1072-6.
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2002: Nishida Koyo; Nose Seiichi; Kuma Akiko; Mukai Takahiro; Kawakami Shigeru; Nakashima Mikiro; Sasaki Hitoshi; Sakaeda Toshiyuki; Nakamura Junzo
Absorption characteristics of model compounds with different molecular weights from the serosal caecal surface in rats.
The Journal of pharmacy and pharmacology 2002;54(7):1005-9.
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2002: Kawakami Shigeru; Horimoto Tomomi; Nishida Koyo; Hirayama Ryu; Mukai Takahiro; Nakashima Mikiro; Sasaki Hitoshi; Sakaeda Toshiyuki; Nakamura Junzo
Kidney- and site-selective delivery of 5-fluorouracil utilizing the absorption on the kidney surface in rats.
Biological & pharmaceutical bulletin 2002;25(7):928-30.
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2002: Kawakami Shigeru; Hirayama Ryu; Shoji Keiko; Kawanami Rie; Nishida Koyo; Nakashima Mikiro; Sasaki Hitoshi; Sakaeda Toshiyuki; Nakamura Junzo
Liver- and lobe-selective gene transfection following the instillation of plasmid DNA to the liver surface in mice.
Biochemical and biophysical research communications 2002;294(1):46-50.
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2002: Kawakami Shigeru; Yamashita Fumiyoshi; Nishida Koyo; Nakamura Junzo; Hashida Mitsuru
Glycosylated cationic liposomes for cell-selective gene delivery.
Critical reviews in therapeutic drug carrier systems 2002;19(2):171-90.
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2001: Kawakami S; Nishida K; Mukai T; Yamamura K; Kobayashi K; Sakaeda T; Nakamura J; Nakashima M; Sasaki H
Ocular absorption behavior of palmitoyl tilisolol, an amphiphilic prodrug of tilisolol, for ocular drug delivery.
Journal of pharmaceutical sciences 2001;90(12):2113-20.
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2001: Nishida K; Yoshida Y; Mukai T; Kawakami S; Sakaeda T; Nakashima M; Sasaki H; Nakamura J
Effect of instillation method on the absorption of phenolsulphonphthalein as a model drug from the liver and small intestinal serosal surface in rats.
The Journal of pharmacy and pharmacology 2001;53(10):1341-6.
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2001: Kawakami S; Nishida K; Mukai T; Yamamura K; Nakamura J; Sakaeda T; Nakashima M; Sasaki H
Controlled release and ocular absorption of tilisolol utilizing ophthalmic insert-incorporated lipophilic prodrugs.
Journal of controlled release : official journal of the Controlled Release Society 2001;76(3):255-63.
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2001: Kawakami S; Yamamura K; Mukai T; Nishida K; Nakamura J; Sakaeda T; Nakashima M; Sasaki H
Sustained ocular delivery of tilisolol to rabbits after topical administration or intravitreal injection of lipophilic prodrug incorporated in liposomes.
The Journal of pharmacy and pharmacology 2001;53(8):1157-61.
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2000: Nishida K; Nakakoga Y; Sato N; Kawakami S; Mukai T; Sasaki H; Sakaeda T; Nakamura J
Effect of viscous additives on drug absorption from the liver surface in rats using phenol red as a model.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2000;50(3):397-402.
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1999: Yamamura K; Sasaki H; Nakashima M; Ichikawa M; Mukai T; Nishida K; Nakamura J
Characterization of ocular pharmacokinetics of beta-blockers using a diffusion model after instillation.
Pharmaceutical research 1999;16(10):1596-601.
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1999: Nakamura J; Yoshida Y; Mera K; Mukai T; Nishida K; Sasaki H
Continuous microinstillation of phenol red on liver surface for liver site-selective delivery.
Biological & pharmaceutical bulletin 1999;22(7):713-5.
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1999: Mukai T; Arano Y; Nishida K; Sasaki H; Akizawa H; Ogawa K; Ono M; Saji H; Nakamura J
Species difference in radioactivity elimination from liver parenchymal cells after injection of radiolabeled proteins.
Nuclear medicine and biology 1999;26(3):281-9.
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1999: Mukai T; Arano Y; Nishida K; Sasaki H; Saji H; Nakamura J
In-vivo evaluation of indium-111-diethylenetriaminepentaacetic acid-labelling for determining the sites and rates of protein catabolism in mice.
The Journal of pharmacy and pharmacology 1999;51(1):15-20.
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1998: Mukai T; Arano Y; Nishida K; Sasaki H; Nakamura J; Saji H; Yokoyama A
Pharmacokinetic models to evaluate radiolabeling reagents for protein radiopharmaceuticals.
Nuclear medicine and biology 1998;25(1):31-6.
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1997: Nishida K; Sato N; Nakakoga Y; Mukai T; Sasaki H; Nakamura J
Effect of application volume and area on the absorption of phenol red, as a model drug, from the liver surface in rats.
The Journal of pharmacy and pharmacology 1997;49(10):976-80.
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1996: Nishida K; Sato N; Sasaki H; Nakamura J
Absorption characteristics of dextrans with different molecular weights from the liver surface membrane in rats: implications for targeting to the liver.
Journal of drug targeting 1996;4(3):141-50.
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1995: Nishida K; Amagishi H; Sasaki H; Nakamura J
Absorption of phenol red and bromphenol blue as model drugs from the peritoneal cavity around the liver surface in rats.
The Journal of pharmacy and pharmacology 1995;47(12A):1032-5.
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1995: Nishida K; Sato N; Sasaki H; Nakamura J
Effect of albumin on the absorption of phenol red, bromphenol blue and bromosulphonphthalein as model drugs from the liver surface membrane in rats.
Biological & pharmaceutical bulletin 1995;18(11):1548-50.
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1995: Sasaki H; Nagano T; Yamamura K; Nishida K; Nakamura J
Ophthalmic preservatives as absorption promoters for ocular drug delivery.
The Journal of pharmacy and pharmacology 1995;47(9):703-7.
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1995: Nishida K; Sato N; Sasaki H; Nakamura J
Mechanism for drug absorption from rat-liver surface membrane: effect of dose and transport inhibitors on the pharmacokinetics of phenol red.
The Journal of pharmacy and pharmacology 1995;47(3):227-31.
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1995: Sasaki H; Tei C; Nishida K; Nakamura J
Effect of ophthalmic preservatives on serum concentration and local irritation of ocularly applied insulin.
Biological & pharmaceutical bulletin 1995;18(1):169-71.
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1995: Sasaki H; Yamamura K; Tei C; Nishida K; Nakamura J
Ocular permeability of FITC-dextran with absorption promoter for ocular delivery of peptide drug.
Journal of drug targeting 1995;3(2):129-35.
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1994: Sasaki H; Tei C; Yamamura K; Nishida K; Nakamura J
Effect of preservatives on systemic delivery of insulin by ocular instillation in rabbits.
The Journal of pharmacy and pharmacology 1994;46(11):871-5.
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1994: Nishida K; Sato N; Sasaki H; Nakamura J
Absorption of organic anions as model drugs following application to rat liver surface in-vivo.
The Journal of pharmacy and pharmacology 1994;46(11):867-70.
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1994: Nishida K; Kido M; Sasaki H; Nakamura J
Pharmacokinetic analysis of in vivo metabolism of amino acid or dipeptide conjugates of salicylic acid in rabbit intestinal microorganisms.
Pharmaceutical research 1994;11(1):160-74.
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1993: Washio K; Makaya O; Sasaki H; Nishida K; Nakamura J; Shibasaki J
A new aspect of tolbutamide metabolism in the rabbit: the role of 1-butyl-3-(p-formylphenyl)sulphonylurea.
The Journal of pharmacy and pharmacology 1993;45(3):231-3.
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1992: Nakamura J; Kido M; Nishida K; Sasaki H
Effect of oral pretreatment with antibiotics on the hydrolysis of salicylic acid-tyrosine and salicylic acid-methionine prodrugs in rabbit intestinal microorganisms.
Chemical & pharmaceutical bulletin 1992;40(9):2572-5.
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1992: Nakamura J; Asai K; Nishida K; Sasaki H
A novel prodrug of salicylic acid, salicylic acid-glycylglycine conjugate, utilizing the hydrolysis in rabbit intestinal microorganisms.
The Journal of pharmacy and pharmacology 1992;44(9):713-6.
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1992: Nakamura J; Asai K; Nishida K; Sasaki H
A novel prodrug of salicylic acid, salicylic acid-glutamic acid conjugate utilizing hydrolysis in rabbit intestinal microorganisms.
Chemical & pharmaceutical bulletin 1992;40(8):2164-8.
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1992: Nakamura J; Katayama M; Nishida K; Sasaki H
An assessment of indomethacin-induced mucosal damage in vivo by measuring the metabolism of salicylamide in rabbit intestine.
Chemical & pharmaceutical bulletin 1992;40(5):1261-5.
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1992: Nakamura J; Katayama M; Nishida K; Sasaki H
An assessment of mucosal damage in vivo: effect of oral pretreatment with 5-fluorouracil on the intestinal first-pass metabolism of salicylamide in rabbits.
Chemical & pharmaceutical bulletin 1992;40(4):1011-5.
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1992: Nakamura J; Tagami C; Nishida K; Sasaki H
Development of a prodrug of salicylic acid, salicylic acid-L-alanine conjugate, utilizing hydrolysis by rabbit intestinal microorganisms.
The Journal of pharmacy and pharmacology 1992;44(4):295-9.
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1992: Nakamura J; Katayama M; Nishida K; Sasaki H
An assessment of salicylic acid-induced mucosal damage in vivo by measuring the metabolism of salicylamide in rabbit intestine.
Chemical & pharmaceutical bulletin 1992;40(3):815-8.
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1992: Nakamura J; Tagami C; Nishida K; Sasaki H
Unequal hydrolysis of salicylic acid-D-alanine and salicylic acid-L-alanine conjugate in rabbit intestinal microorganisms.
Chemical & pharmaceutical bulletin 1992;40(2):547-9.
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1991: Nakamura J; Katayama M; Kido M; Nishida K; Sasaki H
Decrease of gastrointestinal mucosal damage by salicyluric acid compared with salicylic acid in rabbits.
The Journal of pharmacy and pharmacology 1991;43(11):766-73.
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