Hiroyuki Nakanishi

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Okabe Noriko; Shimizu Kazuya; Ozaki-Kuroda Kumi; Nakanishi Hiroyuki; Morimoto Koji; Takeuchi Masakazu; Katsumaru Hironobu; Murakami Fujio; Takai Yoshimi
Contacts between the commissural axons and the floor plate cells are mediated by nectins.
Okabe Noriko; Ozaki-Kuroda Kumi; Nakanishi Hiroyuki; Shimizu Kazuya; Takai Yoshimi
Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo.
Kawabe Hiroshi; Sakisaka Toshiaki; Yasumi Masato; Shingai Tatsushi; Izumi Genkichi; Nagano Fumiko; Deguchi-Tawarada Maki; Takeuchi Masakazu; Nakanishi Hiroyuki; Takai Yoshimi
A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in Ca(2+)-dependent exocytosis of neurotransmitter.

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2004: Okabe Noriko; Shimizu Kazuya; Ozaki-Kuroda Kumi; Nakanishi Hiroyuki; Morimoto Koji; Takeuchi Masakazu; Katsumaru Hironobu; Murakami Fujio; Takai Yoshimi
Contacts between the commissural axons and the floor plate cells are mediated by nectins.
Developmental biology 2004;273(2):244-56.
2004: Okabe Noriko; Ozaki-Kuroda Kumi; Nakanishi Hiroyuki; Shimizu Kazuya; Takai Yoshimi
Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;230(1):174-86.
2003: Kawabe Hiroshi; Sakisaka Toshiaki; Yasumi Masato; Shingai Tatsushi; Izumi Genkichi; Nagano Fumiko; Deguchi-Tawarada Maki; Takeuchi Masakazu; Nakanishi Hiroyuki; Takai Yoshimi
A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in Ca(2+)-dependent exocytosis of neurotransmitter.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(6):537-46.
2003: Tanaka Yoshinari; Nakanishi Hiroyuki; Kakunaga Shigeki; Okabe Noriko; Kawakatsu Tomomi; Shimizu Kazuya; Takai Yoshimi
Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes: analysis with the N-cadherin dominant negative mutant.
Molecular biology of the cell 2003;14(4):1597-609.
2003: Honda Tomoyuki; Shimizu Kazuya; Kawakatsu Tomomi; Yasumi Masato; Shingai Tatsushi; Fukuhara Atsunori; Ozaki-Kuroda Kumi; Irie Kenji; Nakanishi Hiroyuki; Takai Yoshimi
Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E-cadherin-based cell-cell adhesion.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(1):51-63.
2003: Takai Yoshimi; Nakanishi Hiroyuki
Nectin and afadin: novel organizers of intercellular junctions.
Journal of cell science 2003;116(Pt 1):17-27.
2002: Tanaka Yoshinari; Irie Kenji; Hirota Takeshi; Sakisaka Toshiaki; Nakanishi Hiroyuki; Takai Yoshimi
Ectodomain shedding of nectin-1alpha by SF/HGF and TPA in MDCK cells.
Biochemical and biophysical research communications 2002;299(3):472-8.
2002: Fukuhara Atsunori; Irie Kenji; Nakanishi Hiroyuki; Takekuni Kyoji; Kawakatsu Tomomi; Ikeda Wataru; Yamada Akio; Katata Tatsuo; Honda Tomoyuki; Sato Tatsuhiro; Shimizu Kazuya; Ozaki Harunobu; Horiuchi Hisanori; Kita Toru; Takai Yoshimi
Involvement of nectin in the localization of junctional adhesion molecule at tight junctions.
Oncogene 2002;21(50):7642-55.
2002: Fukuhara Atsunori; Irie Kenji; Yamada Akio; Katata Tatsuo; Honda Tomoyuki; Shimizu Kazuya; Nakanishi Hiroyuki; Takai Yoshimi
Role of nectin in organization of tight junctions in epithelial cells.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(10):1059-72.
2002: Ohtsuka Toshihisa; Takao-Rikitsu Etsuko; Inoue Eiji; Inoue Marie; Takeuchi Masakazu; Matsubara Kaho; Deguchi-Tawarada Maki; Satoh Keiko; Morimoto Koji; Nakanishi Hiroyuki; Takai Yoshimi
Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1.
The Journal of cell biology 2002;158(3):577-90.
2002: Ozaki-Kuroda Kumi; Nakanishi Hiroyuki; Ohta Hiroshi; Tanaka Hiromitsu; Kurihara Hidetake; Mueller Steffen; Irie Kenji; Ikeda Wataru; Sakai Tatsuo; Wimmer Eckard; Nishimune Yoshitake; Takai Yoshimi
Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions.
Current biology : CB 2002;12(13):1145-50.
2002: Peng Ying-Feng; Mandai Kenji; Nakanishi Hiroyuki; Ikeda Wataru; Asada Masanori; Momose Yumiko; Shibamoto Sayumi; Yanagihara Kazuyoshi; Shiozaki Hitoshi; Monden Morito; Takeichi Masatoshi; Takai Yoshimi
Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line.
Oncogene 2002;21(26):4108-19.
2002: Momose Yumiko; Honda Tomoyuki; Inagaki Maiko; Shimizu Kazuya; Irie Kenji; Nakanishi Hiroyuki; Takai Yoshimi
Role of the second immunoglobulin-like loop of nectin in cell-cell adhesion.
Biochemical and biophysical research communications 2002;293(1):45-9.
2002: Yamamoto Yasunori; Mandai Kenji; Okabe Noriko; Hoshino Takashi; Nakanishi Hiroyuki; Takai Yoshimi
Localization of mLin-7 at nectin-based cell-cell junctions.
Oncogene 2002;21(16):2545-54.
2002: Kim Yongman; Ikeda Wataru; Nakanishi Hiroyuki; Tanaka Yoshinari; Takekuni Kyouji; Itoh Shinsuke; Monden Morito; Takai Yoshimi
Association of frabin with specific actin and membrane structures.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(4):413-20.
2002: Nagano Fumiko; Kawabe Hiroshi; Nakanishi Hiroyuki; Shinohara Masahiko; Deguchi-Tawarada Maki; Takeuchi Masakazu; Sasaki Takuya; Takai Yoshimi
Rabconnectin-3, a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein family.
The Journal of biological chemistry 2002;277(12):9629-32.
2002: Mizoguchi Akira; Nakanishi Hiroyuki; Kimura Kazushi; Matsubara Kaho; Ozaki-Kuroda Kumi; Katata Tatsuo; Honda Tomoyuki; Kiyohara Yoshimoto; Heo Kyun; Higashi Mikito; Tsutsumi Tomonari; Sonoda Satomi; Ide Chizuka; Takai Yoshimi
Nectin: an adhesion molecule involved in formation of synapses.
The Journal of cell biology 2002;156(3):555-65.
2002: Nakanishi Hiroyuki; Sasaki Takuya; Takai Yoshimi
Isolation of regulatory proteins for the Rab3 subfamily GTPases.
Methods in molecular biology (Clifton, N.J.) 2002;189():143-56.
2001: Kawabe H; Nakanishi H; Asada M; Fukuhara A; Morimoto K; Takeuchi M; Takai Y
Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells.
The Journal of biological chemistry 2001;276(51):48350-5.
2001: Kodama A; Matozaki T; Shinohara M; Fukuhara A; Tachibana K; Ichihashi M; Nakanishi H; Takai Y
Regulation of Ras and Rho small G proteins by SHP-2.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(10):869-76.
2001: Ikeda W; Nakanishi H; Takekuni K; Itoh S; Takai Y
Identification of splicing variants of Frabin with partly different functions and tissue distribution.
Biochemical and biophysical research communications 2001;286(5):1066-72.
2001: Ikeda W; Nakanishi H; Tanaka Y; Tachibana K; Takai Y
Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation.
Oncogene 2001;20(27):3457-63.
2001: Yokoyama S; Tachibana K; Nakanishi H; Yamamoto Y; Irie K; Mandai K; Nagafuchi A; Monden M; Takai Y
alpha-catenin-independent recruitment of ZO-1 to nectin-based cell-cell adhesion sites through afadin.
Molecular biology of the cell 2001;12(6):1595-609.
2001: Shinohara M; Kodama A; Matozaki T; Fukuhara A; Tachibana K; Nakanishi H; Takai Y
Roles of cell-cell adhesion-dependent tyrosine phosphorylation of Gab-1.
The Journal of biological chemistry 2001;276(22):18941-6.
2001: Sakisaka T; Taniguchi T; Nakanishi H; Takahashi K; Miyahara M; Ikeda W; Yokoyama S; Peng Y F; Yamanishi K; Takai Y
Requirement of interaction of nectin-1alpha/HveC with afadin for efficient cell-cell spread of herpes simplex virus type 1.
Journal of virology 2001;75(10):4734-43.
2001: Nakanishi H; Takai Y
Purification and properties of Rab3 GDP/GTP exchange protein.
Methods in enzymology 2001;329():59-67.
2000: Tachibana K; Nakanishi H; Mandai K; Ozaki K; Ikeda W; Yamamoto Y; Nagafuchi A; Tsukita S; Takai Y
Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteins.
The Journal of cell biology 2000;150(5):1161-76.
2000: Kikyo M; Matozaki T; Kodama A; Kawabe H; Nakanishi H; Takai Y
Cell-cell adhesion-mediated tyrosine phosphorylation of nectin-2delta, an immunoglobulin-like cell adhesion molecule at adherens junctions.
Oncogene 2000;19(35):4022-8.
2000: Nishioka H; Mizoguchi A; Nakanishi H; Mandai K; Takahashi K; Kimura K; Satoh-Moriya A; Takai Y
Localization of l-afadin at puncta adhaerentia-like junctions between the mossy fiber terminals and the dendritic trunks of pyramidal cells in the adult mouse hippocampus.
The Journal of comparative neurology 2000;424(2):297-306.
2000: Ono Y; Nakanishi H; Nishimura M; Kakizaki M; Takahashi K; Miyahara M; Satoh-Horikawa K; Mandai K; Takai Y
Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac.
Oncogene 2000;19(27):3050-8.
2000: Satoh-Horikawa K; Nakanishi H; Takahashi K; Miyahara M; Nishimura M; Tachibana K; Mizoguchi A; Takai Y
Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities.
The Journal of biological chemistry 2000;275(14):10291-9.
2000: Miyahara M; Nakanishi H; Takahashi K; Satoh-Horikawa K; Tachibana K; Takai Y
Interaction of nectin with afadin is necessary for its clustering at cell-cell contact sites but not for its cis dimerization or trans interaction.
The Journal of biological chemistry 2000;275(1):613-8.
1999: Asakura T; Nakanishi H; Sakisaka T; Takahashi K; Mandai K; Nishimura M; Sasaki T; Takai Y
Similar and differential behaviour between the nectin-afadin-ponsin and cadherin-catenin systems during the formation and disruption of the polarized junctional alignment in epithelial cells.
Genes to cells : devoted to molecular & cellular mechanisms 1999;4(10):573-81.
1999: Ikeda W; Nakanishi H; Miyoshi J; Mandai K; Ishizaki H; Tanaka M; Togawa A; Takahashi K; Nishioka H; Yoshida H; Mizoguchi A; Nishikawa S; Takai Y
Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis.
The Journal of cell biology 1999;146(5):1117-32.
1999: Umikawa M; Obaishi H; Nakanishi H; Satoh-Horikawa K; Takahashi K; Hotta I; Matsuura Y; Takai Y
Association of frabin with the actin cytoskeleton is essential for microspike formation through activation of Cdc42 small G protein.
The Journal of biological chemistry 1999;274(36):25197-200.
1999: Takahashi K; Nakanishi H; Miyahara M; Mandai K; Satoh K; Satoh A; Nishioka H; Aoki J; Nomoto A; Mizoguchi A; Takai Y
Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein.
The Journal of cell biology 1999;145(3):539-49.
1999: Mandai K; Nakanishi H; Satoh A; Takahashi K; Satoh K; Nishioka H; Mizoguchi A; Takai Y
Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions.
The Journal of cell biology 1999;144(5):1001-17.
1999: Sakisaka T; Nakanishi H; Takahashi K; Mandai K; Miyahara M; Satoh A; Takaishi K; Takai Y
Different behavior of l-afadin and neurabin-II during the formation and destruction of cell-cell adherens junction.
Oncogene 1999;18(8):1609-17.
1998: Oishi H; Sasaki T; Nagano F; Ikeda W; Ohya T; Wada M; Ide N; Nakanishi H; Takai Y
Localization of the Rab3 small G protein regulators in nerve terminals and their involvement in Ca2+-dependent exocytosis.
The Journal of biological chemistry 1998;273(51):34580-5.
1998: Ohtsuka T; Nakanishi H; Ikeda W; Satoh A; Momose Y; Nishioka H; Takai Y
Nexilin: a novel actin filament-binding protein localized at cell-matrix adherens junction.
The Journal of cell biology 1998;143(5):1227-38.
1998: Obaishi H; Nakanishi H; Mandai K; Satoh K; Satoh A; Takahashi K; Miyahara M; Nishioka H; Takaishi K; Takai Y
Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase.
The Journal of biological chemistry 1998;273(30):18697-700.
1998: Ide N; Hata Y; Hirao K; Irie M; Deguchi M; Yao I; Satoh A; Wada M; Takahashi K; Nakanishi H; Takai Y
Interaction of rat lin-10 with brain-enriched F-actin-binding protein, neurabin-II/spinophilin.
Biochemical and biophysical research communications 1998;244(1):258-62.
1998: Satoh A; Nakanishi H; Obaishi H; Wada M; Takahashi K; Satoh K; Hirao K; Nishioka H; Hata Y; Mizoguchi A; Takai Y
Neurabin-II/spinophilin. An actin filament-binding protein with one pdz domain localized at cadherin-based cell-cell adhesion sites.
The Journal of biological chemistry 1998;273(6):3470-5.
1998: Asakura T; Sasaki T; Nagano F; Satoh A; Obaishi H; Nishioka H; Imamura H; Hotta K; Tanaka K; Nakanishi H; Takai Y
Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae.
Oncogene 1998;16(1):121-30.
1997: Nakanishi H; Obaishi H; Satoh A; Wada M; Mandai K; Satoh K; Nishioka H; Matsuura Y; Mizoguchi A; Takai Y
Neurabin: a novel neural tissue-specific actin filament-binding protein involved in neurite formation.
The Journal of cell biology 1997;139(4):951-61.
1997: Mandai K; Nakanishi H; Satoh A; Obaishi H; Wada M; Nishioka H; Itoh M; Mizoguchi A; Aoki T; Fujimoto T; Matsuda Y; Tsukita S; Takai Y
Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction.
The Journal of cell biology 1997;139(2):517-28.
1997: Fukui K; Sasaki T; Imazumi K; Matsuura Y; Nakanishi H; Takai Y
Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins.
The Journal of biological chemistry 1997;272(8):4655-8.
1997: Wada M; Nakanishi H; Satoh A; Hirano H; Obaishi H; Matsuura Y; Takai Y
Isolation and characterization of a GDP/GTP exchange protein specific for the Rab3 subfamily small G proteins.
The Journal of biological chemistry 1997;272(7):3875-8.
1997: Sasaki T; Shirataki H; Nakanishi H; Takai Y
Rab3A-rabphilin-3A system in neurotransmitter release.
Advances in second messenger and phosphoprotein research 1997;31():279-94.
1996: Kato M; Sasaki T; Ohya T; Nakanishi H; Nishioka H; Imamura M; Takai Y
Physical and functional interaction of rabphilin-3A with alpha-actinin.
The Journal of biological chemistry 1996;271(50):31775-8.
1996: Takai Y; Sasaki T; Shirataki H; Nakanishi H
Rab3A small GTP-binding protein in Ca(2+)-dependent exocytosis.
Genes to cells : devoted to molecular & cellular mechanisms 1996;1(7):615-32.
1996: Matsuda S; Nakanishi H; Sasaki T; Takai Y
A membrane-associated GDP/GTP exchange protein specific for Rho small GTP-binding protein - partial purification and characterization from rat brain.
Oncogene 1996;12(4):915-20.
1995: Araki K; Nakanishi H; Hirano H; Kato M; Sasaki T; Takai Y
Purification and characterization of Rab GDI beta from rat brain.
Biochemical and biophysical research communications 1995;211(1):296-305.
1995: Mizuno T; Nakanishi H; Takai Y
Purification and properties of Rac2 from human leukemia cells.
Methods in enzymology 1995;256():15-25.

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Hiroyuki Nakanishi

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