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Peter Bell

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Luk Vandenberghe; Ru Xiao; Peter Bell; Jean Bennett; Rebecca Grant; Tim B Hopkins; Albert M Maguire; James M Wilson
AAV9 targets cone photoreceptors in the nonhuman primate retina.
Sadik H Kassim; William Lagor; Hui Li; Peter Bell; Jeffrey Billheimer; Frank Jacobs; Suryanarayan Somanathan; James M Wilson; Daniel J Rader
Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia.
Lili Wang; Peter Bell; Deirdre McMenamin; Huan Wang; James M Wilson
Hepatic gene transfer in neonatal mice by adeno-associated virus serotype 8 vector.

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All Publications

2013: Luk Vandenberghe; Ru Xiao; Peter Bell; Jean Bennett; Rebecca Grant; Tim B Hopkins; Albert M Maguire; James M Wilson
AAV9 targets cone photoreceptors in the nonhuman primate retina.
PloS one 2013;8(1):e53463.
2013: Sadik H Kassim; William Lagor; Hui Li; Peter Bell; Jeffrey Billheimer; Frank Jacobs; Suryanarayan Somanathan; James M Wilson; Daniel J Rader
Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia.
Human gene therapy 2013;24(1):19-26.
2012: Lili Wang; Peter Bell; Deirdre McMenamin; Huan Wang; James M Wilson
Hepatic gene transfer in neonatal mice by adeno-associated virus serotype 8 vector.
Human gene therapy 2012;23(5):533-9.
2012: Liqing Wang; H Yu; Mark L Batshaw; Peter Bell; D Jones; Jianping Lin; D McMenamin; Hiroki Morizono; H Wang; James M Wilson
Sustained correction of OTC deficiency in spf( ash) mice using optimized self-complementary AAV2/8 vectors.
Gene therapy 2012;19(4):404-10.
2012: Lili Wang; Hongwei Yu; Mark L Batshaw; Peter Bell; David Jones; Jianping Lin; Deirdre McMenamin; Hiroki Morizono; James M Wilson
Preclinical evaluation of a clinical candidate AAV8 vector for ornithine transcarbamylase (OTC) deficiency reveals functional enzyme from each persisting vector genome.
Molecular genetics and metabolism 2012;105(2):203-11.
2012: Wei Chieh Huang; Peter Bell; Artur Vahe Cideciyan; Dina Y Gewaily; Maria P Limberis; Forbes D Manson; Alejandro J Roman; Sam Sadigh; Sharon B Schwartz; Anand Swaroop; James M Wilson; Alan F Wright; Samuel G Jacobson
RPGR-associated retinal degeneration in human X-linked RP and a murine model.
Investigative ophthalmology & visual science 2012;53(9):5594-608.
2011: Lili Wang; Peter Bell; Roberto Calcedo; Jianping Lin; Alice Tarantal; James M Wilson
AAV8-mediated hepatic gene transfer in infant rhesus monkeys (Macaca mulatta).
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(11):2012-20.
2011: Peter Bell; Guangping Gao; Mark E Haskins; Robert J McCarter; Alice Tarantal; Lili Wang; Hongwei Yu; Yanqing Zhu; James M Wilson
Inverse zonation of hepatocyte transduction with AAV vectors between mice and non-human primates.
Molecular genetics and metabolism 2011;104(3):395-403.
2011: Lili Wang; Peter Bell; Roberto Calcedo; Rebecca L Grant; Jianping Lin; Don L Siegel; James M Wilson
Impact of pre-existing immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors.
Human gene therapy 2011;22(11):1389-401.
2011: Tomas S Aleman; Peter Bell; Artur Vahe Cideciyan; Wei Chieh Huang; Geoffrey K Aguirre; Maria P Limberis; Cristina L Mullins; Melani B Olivares; Alejandro J Roman; Sharon B Schwartz; Edwin M Stone; Alexander Sumaroka; Frank F Tsai; Luk H Vandenberghe; James M Wilson; Samuel G Jacobson
Human CRB1-associated retinal degeneration: comparison with the rd8 Crb1-mutant mouse model.
Investigative ophthalmology & visual science 2011;52(9):6898-910.
2011: Peter Bell; Roberto Calcedo; Shu-Jen Chen; Guangping Gao; Mark E Haskins; Meg M Sleeper; Luk Vandenberghe; Huan Wang; Lili Wang; Chick Weisse; Elanor Withnall; James M Wilson
Evaluation of adeno-associated viral vectors for liver-directed gene transfer in dogs.
Human gene therapy 2011;22(8):985-97.
2011: Ekaterina Breous; Suryanarayan Somanathan; Peter Bell; James M Wilson
Inflammation promotes the loss of adeno-associated virus-mediated transgene expression in mouse liver.
Gastroenterology 2011;141(1):348-57, 357.e1-3.
2011: Luk Vandenberghe; Lili Wang; James M Wilson; John H Wolfe; Ru Xiao; Roberto Calcedo; Michael J Castle; Cassia N Cearley; Rebecca Grant; Alexandra C Maguire; Albert M Maguire; Peter Bell; Jean Bennett
Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey.
Science translational medicine 2011;3(88):88ra54.
2010: Suryanarayan Somanathan; Ekaterina Breous; Peter Bell; James M Wilson
AAV vectors avoid inflammatory signals necessary to render transduced hepatocyte targets for destructive T cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(5):977-82.
2010: sadik kassim; Hui Li; Luk Vandenberghe; Christian Hinderer; Peter Bell; Dawn Marchadier; Aisha Wilson; Debra Cromley; Valeska Redon; Hongwei Yu; James M Wilson; Daniel J Rader
Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis.
PloS one 2010;5(10):e13424.
2010: Lili Wang; Roberto Calcedo; Huan Wang; Peter Bell; Rebecca Grant; Luk Vandenberghe; Julio Sanmiguel; Hiroki Morizono; Mark L Batshaw; James M Wilson
The pleiotropic effects of natural AAV infections on liver-directed gene transfer in macaques.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(1):126-34.
2010: Lili Wang; Huan Wang; Peter Bell; Robert J McCarter; Jianping He; Roberto Calcedo; Luk Vandenberghe; Hiroki Morizono; Mark L Batshaw; James M Wilson
Systematic evaluation of AAV vectors for liver directed gene transfer in murine models.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(1):118-25.
2009: Jianping Lin; Roberto Calcedo; Luk Vandenberghe; Peter Bell; Suryanarayan Somanathan; James M Wilson
A new genetic vaccine platform based on an adeno-associated virus isolated from a rhesus macaque.
Journal of virology 2009;83(24):12738-50.
2009: Guangping Gao; Qiang Wang; Roberto Calcedo; Lauren Mays; Peter Bell; Lili Wang; Luk Vandenberghe; Rebecca Grant; Julio Sanmiguel; Emma E Furth; James M Wilson
Adeno-associated virus-mediated gene transfer to nonhuman primate liver can elicit destructive transgene-specific T cell responses.
Human gene therapy 2009;20(9):930-42.
2009: Lauren E Mays; Luk Vandenberghe; Ru Xiao; Peter Bell; Hyun-Joo Nam; Mavis Agbandje-McKenna; James M Wilson
Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6051-60.
2007: Peter Bell; Luk Vandenberghe; Di Wu; Julie Johnston; Maria P Limberis; James M Wilson
A comparative analysis of novel fluorescent proteins as reporters for gene transfer studies.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007;55(9):931-9.
2007: Gary P Kobinger; Joanita Figueredo; Thomas Rowe; Yan Zhi; Guangping Gao; Julio Sanmiguel; Peter Bell; Nelson A Wivel; Lois A Zitzow; Douglas B Flieder; Robert Jeffrey Hogan; James M Wilson
Adenovirus-based vaccine prevents pneumonia in ferrets challenged with the SARS coronavirus and stimulates robust immune responses in macaques.
Vaccine 2007;25(28):5220-31.
2007: Gary P Kobinger; Maria P Limberis; Suri Somanathan; Gregory Schumer; Peter Bell; James M Wilson
Human immunodeficiency viral vector pseudotyped with the spike envelope of severe acute respiratory syndrome coronavirus transduces human airway epithelial cells and dendritic cells.
Human gene therapy 2007;18(5):413-22.
2006: Peter Bell; A David Moscioni; Robert J McCarter; Di Wu; Guangping Gao; Albert Hoang; Julio Sanmiguel; Xun Sun; Nelson A Wivel; Steven E Raper; Emma E Furth; Mark L Batshaw; James M Wilson
Analysis of tumors arising in male B6C3F1 mice with and without AAV vector delivery to liver.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(1):34-44.
2006: David Moscioni; Hiroki Morizono; Robert J McCarter; Adam Stern; Juan Cabrera-Luque; Albert Hoang; Julio Sanmiguel; Di Wu; Peter Bell; Guang-Ping Gao; Steven E Raper; James M Wilson; Mark L Batshaw
Long-term correction of ammonia metabolism and prolonged survival in ornithine transcarbamylase-deficient mice following liver-directed treatment with adeno-associated viral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(1):25-33.
2006: Reed F Johnson; Peter Bell; Ronald N Harty
Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology.
Virology journal 2006;3():31.
2006: Guangping Gao; You Lu; Roberto Calcedo; Rebecca L Grant; Peter Bell; Lili Wang; Joanita Figueredo; Martin Lock; James M Wilson
Biology of AAV serotype vectors in liver-directed gene transfer to nonhuman primates.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(1):77-87.
2005: Peter Bell; Lili Wang; Corinna Lebherz; Douglas B Flieder; Mark S Bove; Di Wu; Guang-Ping Gao; James M Wilson; Nelson A Wivel
No evidence for tumorigenesis of AAV vectors in a large-scale study in mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(2):299-306.
2005: Peter Bell; Maria P Limberis; Guangping Gao; Di Wu; Mark S Bove; Julio Sanmiguel; James M Wilson
An optimized protocol for detection of E. coli beta-galactosidase in lung tissue following gene transfer.
Histochemistry and cell biology 2005;124(1):77-85.
2004: Robert Jeffrey Hogan; Guangping Gao; Thomas Rowe; Peter Bell; Douglas B Flieder; Jason Paragas; Gary P Kobinger; Nelson A Wivel; Ronald G Crystal; Julie Boyer; Heinz Feldmann; Thomas G Voss; James M Wilson
Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1.
Journal of virology 2004;78(20):11416-21.
2004: Thomas Rowe; Guangping Gao; Robert Jeffrey Hogan; Ronald G Crystal; Thomas G Voss; Rebecca L Grant; Peter Bell; Gary P Kobinger; Nelson A Wivel; James M Wilson
Macaque model for severe acute respiratory syndrome.
Journal of virology 2004;78(20):11401-4.
2004: Takashi Irie; Jill Licata; Himangi R Jayakar; Michael A Whitt; Peter Bell; Ronald N Harty
Functional analysis of late-budding domain activity associated with the PSAP motif within the vesicular stomatitis virus M protein.
Journal of virology 2004;78(14):7823-7.
2004: Rita Sarkar; Renee Tetreault; Guangping Gao; Lili Wang; Peter Bell; Randy J Chandler; James M Wilson; Haig Kazazian
Total correction of hemophilia A mice with canine FVIII using an AAV 8 serotype.
Blood 2004;103(4):1253-60.
2003: Kasirajan Ayyanathan; Mark S Lechner; Peter Bell; Gerd G Maul; David C Schultz; Yoshihiko Yamada; Kazuhiro Tanaka; Kiyoyuki Torigoe; Frank J Rauscher
Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation.
Genes & development 2003;17(15):1855-69.
2002: Jeffrey D Dvorin; Peter Bell; Gerd G Maul; Masahiro Yamashita; Michael Emerman; Michael H Malim
Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import.
Journal of virology 2002;76(23):12087-96.
2001: Peter Bell; Luis J Montaner; Gerd G Maul
Accumulation and intranuclear distribution of unintegrated human immunodeficiency virus type 1 DNA.
Journal of virology 2001;75(16):7683-91.
2000: Peter Bell; Paul M Lieberman; Gerd G Maul
Lytic but not latent replication of epstein-barr virus is associated with PML and induces sequential release of nuclear domain 10 proteins.
Journal of virology 2000;74(24):11800-10.
2000: Qiyi Tang; Peter Bell; P Tegtmeyer; Gerd G Maul
Replication but not transcription of simian virus 40 DNA is dependent on nuclear domain 10.
Journal of virology 2000;74(20):9694-700.
2000: D Plehn-Dujowich; Peter Bell; Alexander M Ishov; C Baumann; Gerd G Maul
Non-apoptotic chromosome condensation induced by stress: delineation of interchromosomal spaces.
Chromosoma 2000;109(4):266-79.
2000: Peter Bell; Robert Brazas; D Ganem; Gerd G Maul
Hepatitis delta virus replication generates complexes of large hepatitis delta antigen and antigenomic RNA that affiliate with and alter nuclear domain 10.
Journal of virology 2000;74(11):5329-36.
2000: Gerd G Maul; Dmitri Negorev; Peter Bell; Alexander M Ishov
Review: properties and assembly mechanisms of ND10, PML bodies, or PODs.
Journal of structural biology 2000;129(2-3):278-87.