Nisar Malek

Research Profile

Living Beings

Disorders

Chemicals & Drugs

Anatomy

Physiology

Phenomena

RNA Interference

Procedures

Co-author Network

Publications

TOP 3
Vindhya Palagani; Mona El Khatib; Till Krech; Michael P Manns; Nisar P Malek; Ruben R Plentz
Decrease of CD44-positive Cells Correlates with Tumor Response to Chemotherapy in Patients with Gastrointestinal Cancer.
Murielle P Serres; Uta Kossatz; Yong Chi; James M Roberts; Nisar P Malek; Arnaud Besson
p27(Kip1) controls cytokinesis via the regulation of citron kinase activation.
M Knüppel; S Kubicka; A Vogel; N P Malek; M Schneider; F Papendorf; T Greten; J Wedemeyer; A Schneider
Combination of conservative and interventional therapy strategies for intra- and extrahepatic cholangiocellular carcinoma: a retrospective survival analysis.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Nisar Malek (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Vindhya Palagani; Mona El Khatib; Till Krech; Michael P Manns; Nisar P Malek; Ruben R Plentz
Decrease of CD44-positive Cells Correlates with Tumor Response to Chemotherapy in Patients with Gastrointestinal Cancer.
Anticancer research 2012;32(5):1747-55.
2012: Murielle P Serres; Uta Kossatz; Yong Chi; James M Roberts; Nisar P Malek; Arnaud Besson
p27(Kip1) controls cytokinesis via the regulation of citron kinase activation.
The Journal of clinical investigation 2012;122(3):844-58.
2012: M Knüppel; S Kubicka; A Vogel; N P Malek; M Schneider; F Papendorf; T Greten; J Wedemeyer; A Schneider
Combination of conservative and interventional therapy strategies for intra- and extrahepatic cholangiocellular carcinoma: a retrospective survival analysis.
Gastroenterology research and practice 2012;2012():190708.
2011: Antje Brauckhoff; Mona Malz; Darjus Tschaharganeh; Nisar Malek; Achim Weber; Marc-Oliver Riener; Christopher Soll; Jana Samarin; Michaela Bissinger; Jan Schmidt; et al.
Nuclear expression of the ubiquitin ligase seven in absentia homolog (SIAH)-1 induces proliferation and migration of liver cancer cells.
Journal of hepatology 2011;55(5):1049-57.
2011: Thomas von Hahn; Sandra Ciesek; Gerd Wegener; Ruben R Plentz; Tobias J Weismüller; Heiner Wedemeyer; Michael P Manns; Tim F Greten; Nisar P Malek
Epidemiological trends in incidence and mortality of hepatobiliary cancers in Germany.
Scandinavian journal of gastroenterology 2011;46(9):1092-8.
2011: Norman Woller; Sarah Knocke; Bettina Mundt; Engin Gürlevik; Nina Strüver; Arnold Kloos; Bita Boozari; Peter Schache; Michael P Manns; Nisar P Malek; et al.
Virus-induced tumor inflammation facilitates effective DC cancer immunotherapy in a Treg-dependent manner in mice.
The Journal of clinical investigation 2011;121(7):2570-82.
2010: Ietidal E Mohamed; Stefan Kehraus; Anja Krick; Gabriele M König; Gerhard Kelter; Armin Maier; Heinz-Herbert Fiebig; Markus Kalesse; Nisar P Malek; Harald Gross
Mode of action of epoxyphomalins A and B and characterization of related metabolites from the marine-derived fungus Paraconiothyrium sp.
Journal of natural products 2010;73(12):2053-6.
2010: Uta Kossatz; Kai Breuhahn; Benita Wolf; Matthias Hardtke-Wolenski; Ludwig Wilkens; Doris Steinemann; Stephan Singer; Felicitas Brass; Stefan Kubicka; Brigitte Schlegelberger; et al.
The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells.
The Journal of clinical investigation 2010;120(11):3820-33.
2010: N P Malek; A Vogel; M P Manns
[Multimodality treatment for hepatocellular carcinoma].
Der Internist 2010;51(11):1374-81.
2010: Nisar P Malek
CUX1 mediates tumour cell survival: implications for future therapies?
Gut 2010;59(8):1014-5.
2010: Leila Bülow; Irina Nickeleit; Anna-Katharina Girbig; Tobias Brodmann; Andreas Rentsch; Ulrike Eggert; Florenz Sasse; Heinrich Steinmetz; Ronald Frank; Teresa Carlomagno; et al.
Synthesis and biological characterization of argyrin F.
ChemMedChem 2010;5(6):832-6.
2010: Benjamin Stauch; Bernd Simon; Teodora Basile; Gisbert Schneider; Nisar P Malek; Markus Kalesse; Teresa Carlomagno
Elucidation of the structure and intermolecular interactions of a reversible cyclic-peptide inhibitor of the proteasome by NMR spectroscopy and molecular modeling.
Angewandte Chemie (International ed. in English) 2010;49(23):3934-8.
2010: Florian Kühnel; Engin Gürlevik; Thomas C Wirth; Nina Strüver; Nisar P Malek; Martina Müller-Schilling; Michael P Manns; Amancio Carnero; Lars Zender; Stefan Kubicka
Targeting of p53-transcriptional dysfunction by conditionally replicating adenovirus is not limited by p53-homologues.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(5):936-46.
2009: Laura Elisa Buitrago-Molina; Deepika Pothiraju; Jutta Lamlé; Silke Marhenke; Uta Kossatz; Kai Breuhahn; Michael P Manns; Nisar Malek; Arndt Vogel
Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage.
Hepatology (Baltimore, Md.) 2009;50(2):500-9.
2009: Engin Gürlevik; Norman Woller; Peter Schache; Nisar P Malek; Thomas C Wirth; Lars Zender; Michael P Manns; Stefan Kubicka; Florian Kühnel
p53-dependent antiviral RNA-interference facilitates tumor-selective viral replication.
Nucleic acids research 2009;37(12):e84.
2009: P Schache; E Gürlevik; N Strüver; N Woller; N Malek; L Zender; M Manns; T Wirth; F Kühnel; S Kubicka
VSV virotherapy improves chemotherapy by triggering apoptosis due to proteasomal degradation of Mcl-1.
Gene therapy 2009;16(7):849-61.
2009: Ramakrishna Edukulla; Edukulla Ramakrishna; Norman Woller; Bettina Mundt; Sarah Knocke; Engin Gürlevik; Michael Saborowski; Nisar Malek; Michael P Manns; Thomas Wirth; et al.
Antitumoral immune response by recruitment and expansion of dendritic cells in tumors infected with telomerase-dependent oncolytic viruses.
Cancer research 2009;69(4):1448-58.
2009: T F Greten; F Korangy; M P Manns; N P Malek
Molecular therapy for the treatment of hepatocellular carcinoma.
British journal of cancer 2009;100(1):19-23.
2009: T F Greten; M P Manns; N Malek
[Sorafenib for the treatment of HCC--the beginning of a new era in the treatment of HCC].
Zeitschrift für Gastroenterologie 2009;47(1):55-60.
2008: Irina Nickeleit; Steffen Zender; Florenz Sasse; Robert Geffers; Gudrun Brandes; Inga Sörensen; Heinrich Steinmetz; Stefan Kubicka; Teresa Carlomagno; Dirk Menche; et al.
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition.
Cancer cell 2008;14(1):23-35.
2007: Uta Kossatz; Nisar P Malek
p27: tumor suppressor and oncogene ...?
Cell research 2007;17(10):832-3.
2007: Timm D Kirchhoff; Joerg S Bleck; Arne Dettmer; Ajay Chavan; Herbert Rosenthal; Sonja Merkesdal; Bernd Frericks; Lars Zender; Nisar P Malek; Tim F Greten; et al.
Transarterial chemoembolization using degradable starch microspheres and iodized oil in the treatment of advanced hepatocellular carcinoma: evaluation of tumor response, toxicity, and survival.
Hepatobiliary & pancreatic diseases international : HBPD INT 2007;6(3):259-66.
2007: Justina D McEvoy; Uta Kossatz; Nisar Malek; Jeffrey D Singer
Constitutive turnover of cyclin E by Cul3 maintains quiescence.
Molecular and cellular biology 2007;27(10):3651-66.
2007: Irina Nickeleit; Steffen Zender; Uta Kossatz; Nisar P Malek
p27kip1: a target for tumor therapies?
Cell division 2007;2():13.
2007: N P Malek; T Greten; S Kubicka
[Systemic treatment of liver and biliary tumors].
Der Internist 2007;48(1):46-9.
2006: Uta Kossatz; Jörg Vervoorts; Irina Nickeleit; Holly A Sundberg; J Simon C Arthur; Michael P Manns; Nisar P Malek
C-terminal phosphorylation controls the stability and function of p27kip1.
The EMBO journal 2006;25(21):5159-70.
2006: Inke Timmerbeul; Carrie M Garrett-Engele; Uta Kossatz; Xueyan Chen; Eduardo Firpo; Viktor Grünwald; Kenji Kamino; Ludwig Wilkens; Ulrich Lehmann; Jan Buer; et al.
Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(38):14009-14.
2006: Arne Dettmer; Timm-D Kirchhoff; Michael Gebel; Lars Zender; Nisar-P Malek; Bernhard Panning; Ajay Chavan; Herbert Rosenthal; Stefan Kubicka; Susanne Krusche; et al.
Combination of repeated single-session percutaneous ethanol injection and transarterial chemoembolisation compared to repeated single-session percutaneous ethanol injection in patients with non-resectable hepatocellular carcinoma.
World journal of gastroenterology : WJG 2006;12(23):3707-15.
2006: Silvia M Sanz-González; Raquel Melero-Fernández de Mera; Nisar P Malek; Vicente Andrés
Atheroma development in apolipoprotein E-null mice is not regulated by phosphorylation of p27(Kip1) on threonine 187.
Journal of cellular biochemistry 2006;97(4):735-43.
2005: J Wedemeyer; N P Malek; M P Manns; M J Bahr
[Molecular therapy in gastroenterology and hepatology].
Der Internist 2005;46(8):861-2, 864-8, 870-2.
2005: André Lechel; Ande Satyanarayana; Zhenyu Ju; Ruben R Plentz; Sonja Schaetzlein; Cornelia Rudolph; Ludwig Wilkens; Stephanie U Wiemann; Gabriele Saretzki; Nisar P Malek; et al.
The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo.
EMBO reports 2005;6(3):275-81.
2005: Timm Kirchhoff; Lars Zender; Sonja Merkesdal; Bernd Frericks; Nisar Malek; Joerg Bleck; Stefan Kubicka; Stefan Baus; Ajay Chavan; Michael-P Manns; et al.
Initial experience from a combination of systemic and regional chemotherapy in the treatment of patients with nonresectable cholangiocellular carcinoma in the liver.
World journal of gastroenterology : WJG 2005;11(8):1091-5.
2005: Lars Zender; Sebastian Hütker; Bettina Mundt; Morlen Waltemathe; Christian Klein; Christian Trautwein; Nisar P Malek; Michael Peter Manns; Florian Kühnel; Stefan Kubicka
NFkappaB-mediated upregulation of bcl-xl restrains TRAIL-mediated apoptosis in murine viral hepatitis.
Hepatology (Baltimore, Md.) 2005;41(2):280-8.
2004: Uta Kossatz; Nils Dietrich; Lars Zender; Jan Buer; Michael P Manns; Nisar P Malek
Skp2-dependent degradation of p27kip1 is essential for cell cycle progression.
Genes & development 2004;18(21):2602-7.
2004: Florian Kühnel; Corinna Fritsch; Sabine Krause; Bettina Mundt; Thomas Wirth; Yasmin Paul; Nisar Peter Malek; Lars Zender; Michael Peter Manns; Stefan Kubicka
Doxycycline regulation in a single retroviral vector by an autoregulatory loop facilitates controlled gene expression in liver cells.
Nucleic acids research 2004;32(3):e30.
2003: Lars Zender; Sebastian Hutker; Christian Liedtke; Hans Ludger Tillmann; Steffen Zender; Bettina Mundt; Morlen Waltemathe; Thomas Gosling; Peer Flemming; Nisar Peter Malek; et al.
Caspase 8 small interfering RNA prevents acute liver failure in mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7797-802.
2003: S Kubicka; N P Malek; L Zender
[Hepatocellular carcinoma--a chemosensitive tumor?].
Deutsche medizinische Wochenschrift (1946) 2003;128 Suppl 2():S115-7.
2000: C T Bock; N P Malek; H L Tillmann; M P Manns; C Trautwein
The enhancer I core region contributes to the replication level of hepatitis B virus in vivo and in vitro.
Journal of virology 2000;74(5):2193-202.
2000: J Plümpe; N P Malek; C T Bock; T Rakemann; M P Manns; C Trautwein
NF-kappaB determines between apoptosis and proliferation in hepatocytes during liver regeneration.
American journal of physiology. Gastrointestinal and liver physiology 2000;278(1):G173-83.
1998: C Trautwein; T Rakemann; N P Malek; J Plümpe; G Tiegs; M P Manns
Concanavalin A-induced liver injury triggers hepatocyte proliferation.
The Journal of clinical investigation 1998;101(9):1960-9.
1998: N P Malek; J Pluempe; S Kubicka; M P Manns; C Trautwein
Molecular mechanisms of TNF receptor-mediated signaling.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;147():97-106.
1997: N P Malek; J Casper; L H Looijenga; T Strohmeyer; H J Schmoll; A Nordheim; R Janknecht
Quantification of additional short arms of chromosome 12 in germ cell tumours using the polymerase chain reaction.
European journal of cancer (Oxford, England : 1990) 1997;33(9):1488-94.
1996: N P Malek; K Ocran; U J Tietge; H Maschek; K F Gratz; C Trautwein; S Wagner; M P Manns
A case of the yellow nail syndrome associated with massive chylous ascites, pleural and pericardial effusions.
Zeitschrift für Gastroenterologie 1996;34(11):763-6.